Relevant bibliographies by topics / Triazolopyridine derivatives

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Academic literature on the topic 'Triazolopyridine derivatives'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Triazolopyridine derivatives"

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Flefel, Eman M., Walaa I. El-Sofany, Mahmoud El-Shahat, Arshi Naqvi, and Eman Assirey. "Synthesis, Molecular Docking and in Vitro Screening of Some Newly Synthesized Triazolopyridine, Pyridotriazine and Pyridine–Pyrazole Hybrid Derivatives." Molecules 23, no. 10 (2018): 2548. http://dx.doi.org/10.3390/molecules23102548.

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A series of novel pyridine and fused pyridine derivatives have been prepared starting from 6-(3,4-dimethylphenyl)-2-hydrazinyl-4-(thiophen-2-yl)-pyridine-3-carbonitrile 1 which on treatment with appropriate formic acid, acetic acid/ acetic anhydride, benzoyl chloride and/or carbon disulfide afforded the corresponding triazolopyridine derivatives 2–5. Also, treatment of hydrazide 1 with diethyloxalate, chloroacetyl chloride, chloroacetic acid and/or 1,2-dichloroethane yielded the corresponding pyridotriazine derivatives 7–10. Further transformation of compound 1 with a different active methylen
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2

Ryu, Hwani, Ky-Youb Nam, Hyo Jeong Kim, et al. "Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor." International Journal of Molecular Sciences 22, no. 14 (2021): 7330. http://dx.doi.org/10.3390/ijms22147330.

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More than 80% of colorectal cancer patients have adenomatous polyposis coli (APC) mutations, which induce abnormal WNT/β-catenin activation. Tankyrase (TNKS) mediates the release of active β-catenin, which occurs regardless of the ligand that translocates into the nucleus by AXIN degradation via the ubiquitin-proteasome pathway. Therefore, TNKS inhibition has emerged as an attractive strategy for cancer therapy. In this study, we identified pyridine derivatives by evaluating in vitro TNKS enzyme activity and investigated N-([1,2,4]triazolo[4,3-a]pyridin-3-yl)-1-(2-cyanophenyl)piperidine-4-carb
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3

Shashi Nayana, M. Ravi, Y. Nataraja Sekhar, N. Siva Kumari, S. K. Mahmood, and Muttineni Ravikumar. "CoMFA and docking studies on triazolopyridine oxazole derivatives as p38 MAP kinase inhibitors." European Journal of Medicinal Chemistry 43, no. 6 (2008): 1261–69. http://dx.doi.org/10.1016/j.ejmech.2007.07.010.

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4

Liu, Jing-Ying, Hong-En Zhang, Cheng Wang, et al. "Design, synthesis, and antitumor evaluation of triazolopyridine derivatives as novel inhibitors for BRD4." European Journal of Medicinal Chemistry 285 (March 2025): 117272. https://doi.org/10.1016/j.ejmech.2025.117272.

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5

Juan, S. Gómez-Jeria, and J. Valenzuela-Hueichaqueo Nahuel. "The relationships between electronic structure and human A1 adenosine receptor binding affinity in a series of triazolopyridine derivatives." Chemistry Research Journal 5, no. 4 (2020): 226–36. https://doi.org/10.5281/zenodo.13142828.

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<strong>Abstract </strong>Some triazolopyridine derivatives present a good binding affinity for the human adenosine A<sub>1</sub> receptor. In this paper we present the results of the examination of the relationships between the electronic structure of these molecules and the A<sub>1</sub> receptor binding affinity. The Klopman-Peradejordi-G&oacute;mez method was employed. A statistically significant equation, involving four local atomic reactivity indices, was obtained. Starting from the QSAR results we built the 2D-pharemacophore including the suggested interactions with the binding site. On
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6

Bandaru, N. V. M. Rao, Ashna Fathima, Vandana Joshi, et al. "Design, synthesis, and biological evaluation of substituted benzyl-triazolopyridine derivatives as non-hydroxamate based HDAC8 inhibitors." European Journal of Medicinal Chemistry Reports 13 (April 2025): 100255. https://doi.org/10.1016/j.ejmcr.2025.100255.

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7

Guba, Wolfgang, Matthias Nettekoven, Bernd Püllmann, Claus Riemer, and Sébastien Schmitt. "Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?" Bioorganic & Medicinal Chemistry Letters 14, no. 12 (2004): 3307–12. http://dx.doi.org/10.1016/j.bmcl.2004.03.104.

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8

Sachdeva, Tanisha, May Lee Low, Chun‐Wai Mai, Siew Lee Cheong, Yun Khoon Liew, and Marilyn Daisy Milton. "Design, Synthesis and Characterisation of Novel Phenothiazine‐Based Triazolopyridine Derivatives: Evaluation of Anti‐Breast Cancer Activity on Human Breast Carcinoma." ChemistrySelect 4, no. 43 (2019): 12701–7. http://dx.doi.org/10.1002/slct.201903203.

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9

Tian, Chenyu, Guo Zhang, Ziyi Xia, Nanjun Chen, Shengyong Yang, and Linli Li. "Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model." European Journal of Medicinal Chemistry 231 (March 2022): 114122. http://dx.doi.org/10.1016/j.ejmech.2022.114122.

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10

Chiassai, Leonardo, Rafael Ballesteros-Garrido, Maria Paz Clares, Enrique García-España, Rafael Ballesteros, and Belén Abarca. "Combining Amines and 3-(2-Pyridyl)-[1,2,3]Triazolo[1,5-a]pyridine: An Easy Access to New Functional Polynitrogenated Ligands." Synthesis 51, no. 21 (2019): 4034–42. http://dx.doi.org/10.1055/s-0037-1611901.

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Triazolopyridine-pyridine amine ligands are easily obtained by means of either thermal- or copper(II)-mediated reactions. Starting from a readily accessible iodo derivative of triazolopyridine-pyridine and different amines, this new family of compounds combines aromatic and aliphatic nitrogen atoms with promising coordinating properties. Furthermore, chemical derivatization of a new triazolopyridine-pyridine diamine compound, N1-[6-([1,2,3]triazolo[1,5-a]pyridin-3-yl)pyridin-2-yl]ethan-1,2-diamine, allows the preparation of several remote-pyridine-containing ligands.
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Dissertations / Theses on the topic "Triazolopyridine derivatives"

1

Yang, Chia-Jung, and 楊佳容. "Investigation of triazolopyridine derivatives in organic light emitting devices." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/67654710397119536840.

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碩士<br>國立中山大學<br>光電工程學系研究所<br>104<br>In this thesis, we developed and analyzed the PhOLED based on triazolopyridine derivatives, TRP-01、TRP-02、TRP-03 and TRP-04. The triplet energy of TRP series was about 2.5 eV, so green PhOLEDs were developed by using the TRP series as the host of green emitter fac-tris(2-phenylpyridinato-N, C2’) iridium (III) [Ir(ppy)3] with triplet energy gap about 2.34 eV. In the fourth chapter, the effect of concentration of guest material on device performance was discussed first. The optimization parameters of devices was then discussed. TRP-02 shows the best device per
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