Relevant bibliographies by topics / Triazolothiadiazine

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Academic literature on the topic 'Triazolothiadiazine'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Triazolothiadiazine"

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Mostafa, Mohamed S., Ibrahim Ali M. Radini, Naglaa M. Abd El-Rahman, and Rizk E. Khidre. "Synthetic Methods and Pharmacological Potentials of Triazolothiadiazines: A Review." Molecules 29, no. 6 (2024): 1326. http://dx.doi.org/10.3390/molecules29061326.

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This review article examines the synthetic pathways for triazolothiadiazine derivatives, such as triazolo[3,4-b]thiadiazines, triazolo[5,1-b]thiadiazines, and triazolo[4,3-c]thiadiazines, originating from triazole derivatives, thiadiazine derivatives, or thiocarbohydrazide. The triazolothiadiazine derivatives exhibit several biological actions, including antibacterial, anticancer, antiviral, antiproliferative, analgesic, anti-inflammatory, and antioxidant properties. The review article aims to assist researchers in creating new biologically active compounds for designing target-oriented triazo
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2

Hassanien, Abu Zeid Abd El-Baset. "Phthalazinone in Heterocyclic Synthesis: Synthesis of Some s-Triazole, s-Triazolothiadiazine, s-Triazolothiadiazine, and s-Triazolothiadiazole Derivatives as Pharmaceutical Interest." Phosphorus, Sulfur, and Silicon and the Related Elements 178, no. 9 (2003): 1987–97. http://dx.doi.org/10.1080/10426500390228666.

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3

Bhat, Mashooq Ahmad, Abdul Arif Khan, Shahanavaj Khan, and Abdullah Al-Dhfyan. "Synthesis of New [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazines and Study of Their Anti-Candidaland Cytotoxic Activities." Journal of Chemistry 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/897141.

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New triazolothiadiazine derivatives5a–hwere synthesized from 4-amino-3-(4-pyridyl)-5-mercapto-4H-1,2,4-triazole (3) with substituted aryl hydrazonoyl chlorides4a–h. The compounds were testedin vitroagainst elevenCandidaspecies and compared with standard drug ketoconazole. Among these compounds, the compounds bearingp-chlorophenyl5e,p-methoxyphenyl5c, phenyl5a,andp-sulphonamidophenyl5gsubstituents on triazolothiadiazine system were found to be the most effective derivatives againstCandidaspecies. Compound5ewas the most effective compound againstC. parapsilosis(ATCC 22019),C. albicans(ATCC 66027
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Abdelhameed, Reda M., Hassan A. El-Sayed, Mahmoud El-Shahat, Ahmed A. El-Sayed, and Osama M. Darwesh. "Novel Triazolothiadiazole and Triazolothiadiazine Derivatives Containing Pyridine Moiety: Design, Synthesis, Bactericidal and Fungicidal Activities." Current Bioactive Compounds 14, no. 2 (2018): 169–79. http://dx.doi.org/10.2174/1573407213666170127095158.

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Aychiluhim, Tewodros Birhanu, and Vedula Rajeswar Rao. "Efficient, One-Pot Synthesis of Triazolothiadiazinyl-pyrazolone and Pyrazolyl-triazolothiadiazine Derivatives via Multicomponent Reaction." Synthetic Communications 44, no. 10 (2014): 1422–29. http://dx.doi.org/10.1080/00397911.2012.721917.

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Hussein, Mostafa A., Refaat M. Shaker, Mohammed A. Ameen, and Mohammed F. Mohammed. "Synthesis, anti-inflammatory, analgesic, and antibacterial activities of some triazole, triazolothiadiazole, and triazolothiadiazine derivatives." Archives of Pharmacal Research 34, no. 8 (2011): 1239–50. http://dx.doi.org/10.1007/s12272-011-0802-z.

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Tang, Zhiren, Yang Peng, and Fangming Liu. "Design and synthesis of novel quinoline derivatives bearing oxadiazole, isoxazoline, triazolothiadiazole, triazolothiadiazine, and piperazine moieties." Journal of Heterocyclic Chemistry 57, no. 6 (2020): 2330–38. http://dx.doi.org/10.1002/jhet.3907.

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8

Khan, Imtiaz, Shahid Hameed, Najim A. Al-Masoudi, Nabeel A. Abdul-Reda, and Jim Simpson. "New triazolothiadiazole and triazolothiadiazine derivatives as kinesin Eg5 and HIV inhibitors: synthesis, QSAR and modeling studies." Zeitschrift für Naturforschung B 70, no. 1 (2015): 47–58. http://dx.doi.org/10.1515/znb-2014-0162.

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AbstractA new series of fused 1,2,4-triazoles, namely 6-aryl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 3a–h and 4a–f as well as 6-aryl-3-(furan-2-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines 5a–h, were synthesized by the condensation of 4-amino-5-(furan-2-yl)-4H-1,2,4-triazole-3-thiol (2) with substituted aromatic acids and phenacyl bromides, respectively. The structures of the newly synthesized compounds were established using spectroscopic analysis, while that of 3e was confirmed independently by a single-crystal X-ray structure determination. The compounds were evaluated
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Aychiluhim, Tewodros Birhanu, and Vedula Rajeswar Rao. "ChemInform Abstract: Efficient, One-Pot Synthesis of Triazolothiadiazinyl-pyrazolone and Pyrazolyl-triazolothiadiazine Derivatives via Multicomponent Reaction." ChemInform 45, no. 42 (2014): no. http://dx.doi.org/10.1002/chin.201442195.

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10

Appell, Michael, David L. Compton, and Kervin O. Evans. "Predictive Quantitative Structure–Activity Relationship Modeling of the Antifungal and Antibiotic Properties of Triazolothiadiazine Compounds." Methods and Protocols 4, no. 1 (2020): 2. http://dx.doi.org/10.3390/mps4010002.

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Predictive models were developed using two-dimensional quantitative structure activity relationship (QSAR) methods coupled with B3LYP/6-311+G** density functional theory modeling that describe the antimicrobial properties of twenty-four triazolothiadiazine compounds against Aspergillus niger, Aspergillus flavus and Penicillium sp., as well as the bacteria Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. B3LYP/6-311+G** density functional theory calculations indicated the triazolothiadiazine derivatives possess only modest variation between the frontier or
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Book chapters on the topic "Triazolothiadiazine"

1

Hazarika, Biki, Lal Ropuia, and Ved Prakash Singh. "Biological Relevance and Applications of Triazolothiadiazole Exploring Interactions, Synthesis, and Mechanisms." In Advances in Bioinformatics and Biomedical Engineering. IGI Global, 2024. http://dx.doi.org/10.4018/979-8-3693-7520-4.ch002.

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Fused sulfur heterocycles, such as triazolothiadiazoles, contain four nitrogen atoms and one sulfur atom as heteroatoms in their structure. These elements impart electron-donating and electron-withdrawing properties, influencing the reactivity and chemical behaviour of the compounds. Such effects contribute to various chemical interactions, including coordination with metals and hydrogen bonding. For example, in drug discovery, these interactions play a role in binding with proteins through non-covalent interactions. Additionally, the electronic properties of this heterocycle can interact with
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Journal articles
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