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Journal articles on the topic 'Trigeminal complex'

Author: Grafiati

Published: 24 February 2024

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1

Brown, Jeffrey A. "The Trigeminal Complex." Neurosurgery Clinics of North America 8, no. 1 (1997): 1–10. http://dx.doi.org/10.1016/s1042-3680(18)30333-4.

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Mehnert, Jan, Hauke Basedau, Lisa-Marie Sturm, Trine Nielsen, Rigmor Højland Jensen, and Arne May. "Functional brainstem representations of the human trigeminal cervical complex." Cephalalgia 43, no. 5 (2023): 033310242311748. http://dx.doi.org/10.1177/03331024231174862.

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Background The human in-vivo functional somatotopy of the three branches of the trigeminal (V1, V2, V3) and greater occipital nerve in brainstem and also in thalamus and insula is still not well understood. Methods After preregistration (clinicaltrials.gov: NCT03999060), we mapped the functional representations of this trigemino-cervical complex non-invasively in 87 humans using high-resolution protocols for functional magnetic resonance imaging during painful electrical stimulation in two separate experiments. The imaging protocol and analysis was optimized for the lower brainstem and upper s

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3

BALYAZINA, E. V., T. A. ISAKHANOVA, and N. A. ALEKSEEVA. "CLASSICAL TRIGEMINAL NEURALGIA COMPLEX THERAPY." Kubanskij nauchnyj medicinskij vestnik 1, no. 2 (2017): 21–24. http://dx.doi.org/10.25207/1608-6228-2017-2-21-24.

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4

Clement, M. E., and R. B. McCall. "Characterization of midline medulla role in the trigeminal depressor response." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 256, no. 5 (1989): R1111—R1120. http://dx.doi.org/10.1152/ajpregu.1989.256.5.r1111.

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The purpose of the present investigation was to determine the role of the midline medulla in mediating the trigeminal depressor response. Previously we found that lesions of the midline medulla abolished the decrease in blood pressure resulting from electrical stimulation of the spinal trigeminal complex. Electrical stimulation (5 Hz) of the spinal trigeminal tract elicited a decrease in arterial blood pressure that was associated with an inhibition of sympathetic nerve activity recorded from the inferior cardiac nerve of anesthetized cats. The effect of single shocks applied to the trigeminal

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Chávez, Gabriela-del-Rocío Chávez, Antonio A. F. De Salles, Timothy D. Solberg, Alessandra Pedroso, Dulce Espinoza, and Pablo Villablanca. "Three-dimensional Fast Imaging Employing Steady-state Acquisition Magnetic Resonance Imaging for Stereotactic Radiosurgery of Trigeminal Neuralgia." Neurosurgery 56, no. 3 (2005): E628. http://dx.doi.org/10.1227/01.neu.0000154709.44776.50.

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Abstract OBJECTIVE: The aim of this study was to demonstrate the use and applications of the three-dimensional fast imaging employing steady-state acquisition (3-D-FIESTA) magnetic resonance imaging sequence in targeting and planning for stereotactic radiosurgery of trigeminal neuralgia. METHODS: A 3-D-FIESTA sequence for visualization of cranial nerves in the cranial base was added to the routine magnetic resonance imaging scan to enhance the treatment planning for trigeminal neuralgia. T1-weighted images, 1 mm thick, were directly compared with the FIESTA sequence for the exact visualization

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6

Visconti, Ciro, Leone Leone, Michele Mario Zarrelli, and Alfredo Del Gaudio. "Cervical Spinal Dorsal Root Stimulation in Trigeminal Neuralgia." Pain Medicine Case Reports 5, no. 8 (2021): 379–83. http://dx.doi.org/10.36076/pmcr.2021.5.8.

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BACKGROUND: The treatment of trigeminal neuralgia is a challenge especially for cases refractory to the common standard of care. Neurostimulation for pain relief has been used over the years with different targets and modalities. Few reports exist about the stimulation of high cervical spinal dorsal roots to treat trigeminal pain. CASE REPORT: We report a case of a refractory secondary trigeminal neuralgia that was progressively resistant to various treatments. A trial for upper cervical spinal dorsal root stimulation provided immediate good facial pain relief, evoking paresthesias only in the

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Gaydhanker, Anuradha Prasanna, and Prasanna Shravan Gaydhanker. "A study on trigeminal nerve: Does superior cerebellar artery causes trigeminal neuralgia." Indian Journal of Clinical Anatomy and Physiology 9, no. 3 (2022): 174–78. http://dx.doi.org/10.18231/j.ijcap.2022.037.

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Our brain is the most complex organ in our body which conducts various complex functions and this level of complexity is operated by different structures of the brain. The complexity of relaying information between brain and different parts of the body is conducted by 12 pairs of cranial nerves. Out of 12 pairs of cranial nerves, the most complex and largest nerve is know as trigeminal nerve which is responsible for sensation of face and motor functions such as biting and chewing. Sometimes due to offendation of this nerve typically by Superior Cerebellar Artery leads to most excruciating pain

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Igawa, Kaori, Hideki Funahashi, Yu Miyahara, et al. "Distribution of hemokinin-1 in the rat trigeminal ganglion and trigeminal sensory nuclear complex." Archives of Oral Biology 79 (July 2017): 62–69. http://dx.doi.org/10.1016/j.archoralbio.2017.03.004.

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Jones, Lauren M., SooHyun Lee, Jason C. Trageser, Daniel J. Simons, and Asaf Keller. "Precise Temporal Responses in Whisker Trigeminal Neurons." Journal of Neurophysiology 92, no. 1 (2004): 665–68. http://dx.doi.org/10.1152/jn.00031.2004.

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The ability of rats using their whiskers to perform fine tactile discrimination rivals that of humans using their fingertips. Rats must perform these discriminations rapidly and accurately while palpating the environment with their whiskers. This suggests that whisker-derived inputs produce a robust and reliable code, capable of capturing complex, high-frequency information. The first neural representation of whisker-derived stimulus information is in primary afferent neurons of the trigeminal ganglion. Here we demonstrate that there is a continuum of direction-dependent response profiles in t

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10

Rigoard, Philippe, Maxime Billot, Maarten Moens, et al. "Evaluation of External Trigeminal Nerve Stimulation to Prevent Cerebral Vasospasm after Subarachnoid Hemorrhage Due to Aneurysmal Rupture: A Randomized, Double-Blind Proof-of-Concept Pilot Trial (TRIVASOSTIM Study)." International Journal of Environmental Research and Public Health 20, no. 10 (2023): 5836. http://dx.doi.org/10.3390/ijerph20105836.

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Cerebral vasospasm remains the most frequent and devastating complication after subarachnoid aneurysmal hemorrhage because of secondary cerebral ischemia and its sequelae. The underlying pathophysiology involves vasodilator peptide release (such as CGRP) and nitric oxide depletion at the level of the precapillary sphincters of the cerebral (internal carotid artery network) and dural (external carotid artery network) arteries, which are both innervated by craniofacial autonomic afferents and tightly connected to the trigeminal nerve and trigemino-cervical nucleus complex. We hypothesized that t

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Gajski, Domagoj, Alicia Dennis, and Kenan Arnautović. "Microsurgical Decompression of Trigeminal Neuralgia Caused by Simultaneous Double Arterial (SCA and AICA) and Petrosal Vein Complex Compression." Journal of Neurological Surgery Part B: Skull Base 79, S 05 (2018): S428—S430. http://dx.doi.org/10.1055/s-0038-1669968.

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Trigeminal neuralgia is a chronic pain disorder affecting the face. In approximately 80% of cases, it is most commonly caused, when the root entry zone (REZ) of the trigeminal nerve is compressed by the superior cerebellar artery (SCA). The etiology of the remaining 20% of cases is distributed among venous, arteriovenous malformations, posterior fossa tumors, multiple sclerosis plaque compressions, and other pathologies. Combinations of those compressive factors are very rare.1 2 3 4 Herein, we present a video clip of microvascular decompression (MVD) in a 73-year-old female, who has failed co

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Terrier, Louis‐Marie, Nouchine Hadjikhani, Stéphane Velut, et al. "The trigeminal system: The meningovascular complex— A review." Journal of Anatomy 239, no. 1 (2021): 1–11. http://dx.doi.org/10.1111/joa.13413.

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13

Jacquin, Mark F., Nicolas L. Chiaia, John H. Haring, and Robert W. Rhoades. "Intersubnuclear Connections within the Rat Trigeminal Brainstem Complex." Somatosensory & Motor Research 7, no. 4 (1990): 399–420. http://dx.doi.org/10.3109/08990229009144716.

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14

LaVail, Jennifer H., Junni Zhan, and Todd P. Margolis. "HSV (Type 1) infection of the trigeminal complex." Brain Research 514, no. 2 (1990): 181–88. http://dx.doi.org/10.1016/0006-8993(90)91414-c.

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Chen, QiLiang, Dae Ik Yi, Josiah Nathan Joco Perez, et al. "The Molecular Basis and Pathophysiology of Trigeminal Neuralgia." International Journal of Molecular Sciences 23, no. 7 (2022): 3604. http://dx.doi.org/10.3390/ijms23073604.

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Trigeminal neuralgia (TN) is a complex orofacial pain syndrome characterized by the paroxysmal onset of pain attacks in the trigeminal distribution. The underlying mechanism for this debilitating condition is still not clearly understood. Decades of basic and clinical evidence support the demyelination hypothesis, where demyelination along the trigeminal afferent pathway is a major driver for TN pathogenesis and pathophysiology. Such pathological demyelination can be triggered by physical compression of the trigeminal ganglion or another primary demyelinating disease, such as multiple sclerosi

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Du, Rose, Devin K. Binder, Van Halbach, Nancy Fischbein, and Nicholas M. Barbaro. "Trigeminal Neuralgia in a Patient with a Dural Arteriovenous Fistula in Meckel's Cave: Case Report." Neurosurgery 53, no. 1 (2003): 216–21. http://dx.doi.org/10.1227/01.neu.0000069535.42897.1f.

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Abstract OBJECTIVE AND IMPORTANCE Trigeminal neuralgia is often the result of vascular compression at the root entry zone of the trigeminal nerve. We report a case of trigeminal neuralgia in a patient with a dural arteriovenous fistula in Meckel's cave. Endovascular closure of the fistula resulted in elimination of the patient's pain at the gasserian ganglion level. CLINICAL PRESENTATION A 77-year-old woman was referred for treatment of trigeminal neuralgia after failed conservative treatment, including multiple gasserian ganglion blocks. Magnetic resonance imaging of the brain suggested a vas

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Tanashyan, M. M., M. Yu Maksimova, S. Yu Ivanov, E. M. Musaeva, and P. A. Fedin. "Trigeminal neuropathy following orthognathic surgery." Neurology, Neuropsychiatry, Psychosomatics 12, no. 4 (2020): 37–42. http://dx.doi.org/10.14412/2074-2711-2020-4-37-42.

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Traumatic trigeminal neuropathy occupies a special place in the pain continuum. The clarification of genesis and clinical and neurophysiological findings makes it possible to perform differentiation treatment.Objective: to evaluate the clinical and neurophysiological efficiency of repetitive magnetic stimulation (RMS) and vitamin B complex therapy for traumatic trigeminal neuropathy.Patients and methods. The investigation enrolled 36 patients (26 women and 10 men) aged 25 to 35 years with inferior alveolar neuropathy following bilateral sagittal split osteotomy. The DN4 questionnaire was used

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Fu, Jia, Guo Mu, Ling Qiu, Jiaomei Zhao та Cehua Ou. "c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia". Molecular Pain 16 (січень 2020): 174480692093085. http://dx.doi.org/10.1177/1744806920930855.

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Trigeminal neuralgia is a common neuropathic pain in the head and face. The pathogenesis of trigeminal neuralgia is complex, and so far, the pathogenesis of trigeminal neuralgia involving peripheral and central nervous inflammation theory has not been explained clearly. The loss of dopamine neurons in striatum may play an important role in the development of trigeminal nerve, but the reason is not clear. C-Abl is a nonreceptor tyrosine kinase, which can be activated abnormally in the environment of neuroinflammation and cause neuron death. We found that in the rat model of infraorbital nerve l

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Furuta, Takahiro, Elena Timofeeva, Keiko Okamoto-Furuta, Martin Deschenes, Kouichi Nakamura, and Takeshi Kaneko. "Inhibitory input from the interpolar nucleus of the spinal trigeminal complex to the principal trigeminal nucleus." Neuroscience Research 58 (January 2007): S160. http://dx.doi.org/10.1016/j.neures.2007.06.661.

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20

Ito, G., Y. Suekawa, M. Watanabe, et al. "P2X7receptor in the trigeminal sensory nuclear complex contributes to tactile allodynia/hyperalgesia following trigeminal nerve injury." European Journal of Pain 17, no. 2 (2012): 185–99. http://dx.doi.org/10.1002/j.1532-2149.2012.00174.x.

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21

Zhu, Zhenghong, Heather R. Bowman, Helen A. Baghdoyan, and Ralph Lydic. "Morphine Increases Acetylcholine Release in the Trigeminal Nuclear Complex." Sleep 31, no. 12 (2008): 1629–37. http://dx.doi.org/10.1093/sleep/31.12.1629.

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22

Satoh, Toru, Keisuke Onoda, and Isao Date. "PREOPERATIVE SIMULATION FOR MICROVASCULAR DECOMPRESSION IN PATIENTS WITH IDIOPATHIC TRIGEMINAL NEURALGIA." Neurosurgery 60, no. 1 (2007): 104–14. http://dx.doi.org/10.1227/01.neu.0000249213.34838.c9.

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Abstract OBJECTIVE Precise assessment of the complex nerve-vessel relationship at the root entry zone of the trigeminal nerve is useful for planning microvascular decompression in patients with idiopathic trigeminal neuralgia. We have applied a fusion imaging technique of three-dimensional (3-D) magnetic resonance cisternography and co-registered 3-D magnetic resonance angiography (MRA) that allows virtual reality for the preoperative simulation of the neurovascular conflict at the trigeminal nerve root entry zone. METHODS Fusion images of 3-D magnetic resonance cisternograms and angiograms we

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23

Shulman, H. M. "Alcoholization of the Hasser's node and sensory root from temporal access in trigeminal neuralgia." Kazan medical journal 67, no. 5 (1986): 339–42. http://dx.doi.org/10.17816/kazmj70694.

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Trigeminal neuralgia is one of the most severe and common forms of facial pain syndrome. Its etiology is varied. Most researchers characterize trigeminal neuralgia as a complex process in which the focus of irritation in the afferent part of the nerve causes changes in the stem and subcortical structures in the form of foci of pathological activity manifested by paroxysms.

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Ishi, Yukitomo, Katsuyuki Asaoka, Taku Sugiyama, et al. "Case Report: Trigeminal Neuralgia Caused by a Minute Meningioma with Hyperostosed Suprameatal Tubercle." Case Reports in Neurology 7, no. 2 (2015): 167–72. http://dx.doi.org/10.1159/000438856.

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Cerebellopontine angle tumors might occasionally provoke trigeminal neuralgia but are usually large enough to be diagnosed radiographically. We present a case of trigeminal neuralgia caused by a very small meningioma covering the suprameatal tubercle that displayed hyperostosis at the entrance of Meckel's cave and was not obvious on routine magnetic resonance (MR) images. A 72-year-old woman with intractable trigeminal neuralgia in the left V3 territory was referred to our institution. Preoperative imaging studies revealed that the left trigeminal nerve was medially distorted at the entrance o

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Streit, W. J., B. A. Schulte, D. J. Balentine, and S. S. Spicer. "Histochemical localization of galactose-containing glycoconjugates in sensory neurons and their processes in the central and peripheral nervous system of the rat." Journal of Histochemistry & Cytochemistry 33, no. 10 (1985): 1042–52. http://dx.doi.org/10.1177/33.10.4045182.

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We studied the distribution of sugar residues in the oligosaccharide chains of complex carbohydrates in tissue sections of rat spinal cord, brainstem, and sensory ganglia using twelve lectin-horseradish peroxidase conjugates. Glycoconjugates containing terminal galactose residues were localized apparently in the Golgi apparatus in a population of predominantly small B-type neurons in spinal and trigeminal ganglia. Large A-type neurons rarely showed reactivity with galactose-binding lectins. A cells stained for glycoconjugates with N-glycosidically linked oligosaccharides and glycogen. The cent

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Komatsu, Fuminari, Mika Komatsu, Antonio Di Ieva, and Manfred Tschabitscher. "Endoscopic approaches to the trigeminal nerve and clinical consideration for trigeminal schwannomas: a cadaveric study." Journal of Neurosurgery 117, no. 4 (2012): 690–96. http://dx.doi.org/10.3171/2012.7.jns11730.

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Object The course of the trigeminal nerve straddles multiple fossae and is known to be very complex. Comprehensive anatomical knowledge and skull base techniques are required for surgical management of trigeminal schwannomas. The aims of this study were to become familiar with the endoscopic anatomy of the trigeminal nerve and to develop a minimally invasive surgical strategy for the treatment of trigeminal schwannomas. Methods Ten fresh cadavers were studied using 5 endoscopic approaches with the aid of 4-mm 0° and 30° endoscopes to identify surgical landmarks associated with the trigeminal n

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Sade, Burak, and Joung H. Lee. "Significance of the tentorial alignment in approaching the trigeminal nerve and the ventral petrous region through the suboccipital retrosigmoid technique." Journal of Neurosurgery 107, no. 5 (2007): 932–36. http://dx.doi.org/10.3171/jns-07/11/0932.

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Object In this study, the authors aimed to identify the factors that would predict the operative distance between the trigeminal nerve (fifth cranial nerve) and the acousticofacial nerve complex (seventh–eighth cranial nerves) preoperatively when approaching the cerebellopontine angle (CPA) through the suboccipital retrosigmoid approach. Methods In 40 consecutive patients who underwent microvascular decompression of the trigeminal nerve via a sub-occipital retrosigmoid approach for trigeminal neuralgia, the following three parameters were assessed on preoperative magnetic resonance images: 1)

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Davis, Karen D., and Jonathan O. Dostrovsky. "Effect of trigeminal subnucleus caudalis cold block on the cerebrovascular-evoked responses of rostral trigeminal complex neurons." Neuroscience Letters 94, no. 3 (1988): 303–8. http://dx.doi.org/10.1016/0304-3940(88)90035-3.

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Gushchina, M. B., A. V. Tereshchenko, D. S. Afanasyeva, E. V. Erokhina, and S. K. Demyanchenko. "A clinical case of complex treatment for paralytic lagophthalmos complicated by neurotrophic keratopathy." Modern technologies in ophtalmology, no. 6 (October 29, 2023): 52–59. http://dx.doi.org/10.25276/2312-4911-2022-6-52-59.

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Introduction. Combined leisure of facial and trigeminal nerves causes paralytic lagophthalmos and severe neurotrophic keratopathy that can lead to significant loss of vision. Material and methods. This article describes a clinical case of step-by-step complex surgical treatment in paralytic lagophthalmos accompanied by neuropathic keratopathy complicated by fistula of corneal graft. Results. The performed three stepped surgeries to improve lagophthalmos and corneal nerve supply resulted in subcompensation of lagophthalmos and restoration of corneal sensitivity up to the low limit. This was acc

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Banczerowski, Péter, Gábor Czigléczki, and István Nyáry. "Long-term effectiveness of an ad hoc tailored titanium implant as a spacer for microvascular decompression in the treatment of trigeminal neuralgia caused by megadolichoectatic basilar artery anomaly: 9-year follow-up." Journal of Neurosurgery 121, no. 6 (2014): 1492–96. http://dx.doi.org/10.3171/2014.8.jns132445.

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An enlarged, elongated, ectatic, and sclerotic aberration of the vertebrobasilar system is known as a megadolichoectatic basilar artery (BA) anomaly. The anomaly is often involved in the pathological process of trigeminal neuralgia by compressing and distorting the trigeminal nerve. First-line medical treatment includes drug therapy, but a second-line surgical procedure could be effective in medication-resistant cases. The authors report the case of a 65-year-old man with a 12-year history of progressing trigeminal neuralgia who underwent microvascular decompression after the first-line drug t

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Meyerson, B. A., and S. Håkanson. "Suppression of Pain in Trigeminal Neuropathy by Electric Stimulation of the Gasserian Ganglion." Neurosurgery 18, no. 1 (1986): 59–66. http://dx.doi.org/10.1227/00006123-198601000-00010.

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Abstract Lesions of the peripheral part of the trigeminal nerve may cause trigeminal neuropathy associated with severe pain. Such pain usually does not respond to carbamazepine and analgesics, and it is continuous and lacks the characteristic paroxysmal character of tic douloureux. These patients often present with complex changes of facial sensibility in the form of dysesthesia, hyperalgesia, and allodynia. The pain sometimes responds favorably to transcutaneous nerve stimulation, but direct stimulation of the trigeminal ganglion and rootlets via an implanted electrode provides a greater like

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Dong, Willie K., Eric H. Chudler, and Yoriko Kawakami. "Tooth pulp-evoked potentials in the trigeminal brainstem nuclear complex." Brain Research 529, no. 1-2 (1990): 131–42. http://dx.doi.org/10.1016/0006-8993(90)90820-2.

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Boissonade, Fiona M., Keith A. Sharkey, and Gregory E. Lucier. "Trigeminal nuclear complex of the ferret: Anatomical and Immunohistochemical studies." Journal of Comparative Neurology 329, no. 3 (1993): 291–312. http://dx.doi.org/10.1002/cne.903290302.

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Ide, Linda S., and H. P. Killackey. "Fine structural survey of the rat's brainstem sensory trigeminal complex." Journal of Comparative Neurology 235, no. 2 (1985): 145–68. http://dx.doi.org/10.1002/cne.902350202.

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Covell, David A., and Drew M. Noden. "Embryonic development of the chick primary trigeminal sensory-motor complex." Journal of Comparative Neurology 286, no. 4 (1989): 488–503. http://dx.doi.org/10.1002/cne.902860407.

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Mahajan, Abhishek, Nilesh P. Sable, Richa Vaish, Aliasgar Moiyadi, Supreeta Arya, and Anil Keith D’Cruz. "Multicompartmental Trigeminal Schwannomas: Dumbbell Tumors Revisited." Journal of Global Oncology 2, no. 6 (2016): 431–35. http://dx.doi.org/10.1200/jgo.2016.006122.

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Multicompartmental trigeminal schwannomas (MTSs) are a rare and complex but treatable group of tumors. Herein, we describe the clinicoradiologic presentation of two patients with MTS. The two illustrated distinct case reports highlight the role of imaging and the outcome of two different types of MTS. The Discussion summarizes the literature to date, which will help the reader diagnose these tumors in a timely manner and manage them appropriately.

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Bruti, G., C. Mostardini, A. Pierallini, V. Villani, C. Modini, and R. Cerbo. "Neurovascular Headache and Occipital Neuralgia Secondary to Bleeding of Bulbocervical Cavernoma." Cephalalgia 27, no. 9 (2007): 1074–79. http://dx.doi.org/10.1111/j.1468-2982.2007.01363.x.

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It has recently been suggested that the trigeminocervical complex plays a crucial role in the pathophysiology of neck discomfort that accompanies migraine attacks. Clinical and neurophysiological data have shown that pain within the occipital area may be transmitted by the first trigeminal branch, which supports an anatomical and functional link between cervical and trigeminal modulation of peripheral afferents. We describe a patient with an acute symptomatic migraine attack and chronic occipital neuralgia, both due to bleeding of a bulbocervical cavernoma. The clinical presentation is also di

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Yokota, T., N. Koyama, and N. Matsumoto. "Somatotopic distribution of trigeminal nociceptive neurons in ventrobasal complex of cat thalamus." Journal of Neurophysiology 53, no. 6 (1985): 1387–400. http://dx.doi.org/10.1152/jn.1985.53.6.1387.

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Recordings were made from single thalamic units in the urethan-chloralose anesthetized cat. Altogether 2,905 trigeminal single units having a receptive field in the contralateral trigeminal integument were isolated from the somatosensory part of nucleus ventralis posteromedialis, or VPM proper. Each isolated unit was tested for responses to a series of mechanical stimuli. The stimuli included brushing the skin, touch, pressure, noxious pinch, and pinpricks. The majority of VPM proper units responded with the greatest discharge frequency to gentle mechanical stimulation: either hair movement or

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Van der Cruyssen, Frederic, and Constantinus Politis. "Neurophysiological aspects of the trigeminal sensory system: an update." Reviews in the Neurosciences 29, no. 2 (2018): 115–23. http://dx.doi.org/10.1515/revneuro-2017-0044.

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AbstractThe trigeminal system is one of the most complex cranial nerve systems of the human body. Research on it has vastly grown in recent years and concentrated more and more on molecular mechanisms and pathophysiology, but thorough reviews on this topic are lacking, certainly on the normal physiology of the trigeminal sensory system. Here we review the current literature on neurophysiology of the trigeminal nerve from peripheral receptors up to its central projections toward the somatosensory cortex. We focus on the most recent scientific discoveries and describe historical relevant researc

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Culoso, Ashley, Cynthia Lowe, and Craig Evinger. "Sex, blinking, and dry eye." Journal of Neurophysiology 123, no. 2 (2020): 831–42. http://dx.doi.org/10.1152/jn.00635.2019.

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Blinking sustains the corneal tear film generated by sexually dimorphic lacrimal and meibomian glands. Our study examines whether trigeminal control of blinking is also sexually dimorphic by investigating trigeminal reflex blinking, associative blink modification, and spontaneous blinking in male and female rats before and after unilateral dry eye caused by exorbital gland removal. Before gland removal, female rats exhibited a lower threshold for evoking trigeminal reflex blinks, a weaker effect of associative blink modification, and longer-duration spontaneous blinks than males. Spontaneous b

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Kanaev, R., A. Kydyrbaeva, and Ch Niyazbekov. "Comprehensive Treatment of Patients With Classical Trigeminal Neuralgia." Bulletin of Science and Practice, no. 9 (September 15, 2023): 151–58. http://dx.doi.org/10.33619/2414-2948/94/18.

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Trigeminal neuralgia is a chronic disease characterized by short paroxysms of intense excruciating shooting pains in the innervation zone of one or more branches of the trigeminal nerve. Trigeminal neuralgia is a common disease, it occurs with a frequency of 4-5 to 30-50 cases per 100,000 population — according to reports, about 15,000 new patients are diagnosed in the United States annually. The practical social severity of trigeminal neuralgia is high — the severity of pain attacks leads to a significant disruption of the flow of the normal rhythm of life of patients. Among the conservative

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Storer, RJ, DC Immke, R. Yin, and PJ Goadsby. "Large Conductance Calcium-Activated Potassium Channels (BKCa) Modulate Trigeminovascular Nociceptive Transmission." Cephalalgia 29, no. 12 (2009): 1242–58. http://dx.doi.org/10.1111/j.1468-2982.2009.01849.x.

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Migraine is a common, disabling, neurological problem whose acute management would benefit from the development of purely neurally acting therapies. The trigeminocervical complex is pivotal in nociceptive signaling in migraine, and is an accepted target for putative antimigraine agents. Whole-cell patch-clamp or extracellular recordings were made of trigeminal neurons identified in rat brainstem slices. Bath application of the large conductance calcium-activated potassium (BKCa) channel opener NS1619 caused a dramatic decrease of cell firing that could be reversed by the co-application of iber

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Son, Byung-chul. "Referred Trigeminal Facial Pain from Occipital Neuralgia Occurring Much Earlier than Occipital Neuralgia." Case Reports in Neurological Medicine 2020 (August 24, 2020): 1–6. http://dx.doi.org/10.1155/2020/8834865.

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We report a very rare case in which a patient believed to have auriculotemporal neuralgia due to the repeated recurrence of paroxysmal stabbing pain in the preauricular temporal region for four years developed occipital neuralgia, which finally improved with decompression of the greater occipital nerve (GON). The pain of occipital neuralgia has been suggested to be referred to the frontoorbital (V1) region through trigeminocervical interneuronal connections in the trigeminal spinal nucleus. However, the reports of such cases are very rare. In occipital neuralgia, the pain referred to the ipsil

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Susanti, Restu. "SUNCT, A RARE TRIGEMINAL PAIN." Collaborative Medical Journal (CMJ) 3, no. 2 (2020): 53–62. http://dx.doi.org/10.36341/cmj.v3i2.1264.

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Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) are a subset of short-lasting unilateral neuralgiform headache attacks. SUNCT is a condition that is rarely encountered and is characterized by typical moderate to severe neuralgia pain located in the first division area of the trigeminal nerve that can be felt in any part of the head. SUNCT can be primary and secondary. Typical SUNCT symptoms include severe unilateral headache with autonomic symptoms with bilateral conjunctival injection and lacrimation with an attack frequency more than 60

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Amendano, Brigette, Suzanne Spriggs, and Ian Cost. "A comparative description of the maxillary and mandibular divisions of the trigeminal nerve in birds." Journal of the Pennsylvania Academy of Science 95, no. 2 (2021): 121–34. http://dx.doi.org/10.5325/jpennacadscie.95.2.0121.

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Abstract For many animals, touch is one of the most crucial senses, as it allows an animal to assess its surroundings, develop properly, and socialize. Remote touch is an essential part of avian survival, as it allows some families of birds to identify prey through changes in pressure. Some birds possess a sensitive bill tip organ filled with a large number of mechanoreceptors to perform remote touch sensation. This implies that they possess a complex trigeminal nerve system. The trigeminal nerve has three divisions (ophthalmic, V1; maxillary, V2; and mandibular, V3) that supply somatosensory

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Danilov, O. D., V. I. Shepitko, O. S. Yakushko, E. V. Stetsuk, and N. V. Boruta. "MORPHOLOGICAL CHARACTERISTICS OF THE TRIGEMINAL NODE OF RATS WHEN CRYOPRESERVED PLACENTA IS INTRODUCED." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 22, no. 3-4 (2022): 152–56. http://dx.doi.org/10.31718/2077-1096.22.3.4.152.

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Cryopreserved placenta preparations have a unique composition of biologically active substances, which determines their multifaceted effect. The aim of our study was to investigate the morphological features of the trigeminal node of rats when cryopreserved placenta was injected. The conducted experimental study showed that a single subcutaneous injection of cryopreserved placenta causes a reaction of the vessels of the microcirculatory bed of the trigeminal node of rats in the first two weeks of observation in the form of an expansion of the diameter of arterioles, capillaries and venul

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Holland, G. R. "Experimental Trigeminal Nerve Injury." Critical Reviews in Oral Biology & Medicine 7, no. 3 (1996): 237–58. http://dx.doi.org/10.1177/10454411960070030301.

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The successful reinnervation of peripheral targets after injury varies with the axonal population of the nerve that is injured and the extent of the dislocation of its central component from the peripheral endoneurial tube. Larger-diameter axons such as those supplying mechanoreceptors recover more readily than narrower axons such as those supplying taste. A complex, bi-directional interaction between lingual epithelium and sprouting nerve results in the redifferentiation of taste buds after denervation. Dentin and the dental pulp provide a strong attraction to sprouting nerves and will become

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Carrasco, Carmen A., David Rojas-Salazar, Renato Chiorino, Juan C. Venega, and Nelson Wohllk. "MELANOTIC NONPSAMMOMATOUS TRIGEMINAL SCHWANNOMA AS THE FIRST MANIFESTATION OF CARNEY COMPLEX." Neurosurgery 59, no. 6 (2006): E1334—E1335. http://dx.doi.org/10.1227/01.neu.0000245608.07570.d2.

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Abstract OBJECTIVE Melanotic schwannoma is a rare neoplasm, classifiable as a peripheral nerve sheath tumor, and differentiated from a typical schwannoma by heavy pigmentation. Psammoma bodies can be visualized in more than 50% of melanotic schwannomas. Half of patients with such “psammomatous melanotic schwannomas” have Carney complex, a dominantly transmitted autosomal disorder. Most recently, the tumor suppressor gene, PRKAR1A, coding for the Type 1α regulatory subunit of protein kinase A was found to be mutated in approximately half of the known Carney complex families. Although cranial sc

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Menon, Nandita, and Anil Kishen. "Nociceptor–Macrophage Interactions in Apical Periodontitis: How Biomolecules Link Inflammation with Pain." Biomolecules 13, no. 8 (2023): 1193. http://dx.doi.org/10.3390/biom13081193.

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Periradicular tissues have a rich supply of peripheral afferent neurons, also known as nociceptive neurons, originating from the trigeminal nerve. While their primary function is to relay pain signals to the brain, these are known to be involved in modulating innate and adaptive immunity by initiating neurogenic inflammation (NI). Studies have investigated neuroanatomy and measured the levels of biomolecules such as cytokines and neuropeptides in human saliva, gingival crevicular fluid, or blood/serum samples in apical periodontitis (AP) to validate the possible role of trigeminal nociceptors

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Bates, Carolyn A., and Herbert P. Killackey. "The organization of the neonatal rat's brainstem trigeminal complex and its role in the formation of central trigeminal patterns." Journal of Comparative Neurology 240, no. 3 (1985): 265–87. http://dx.doi.org/10.1002/cne.902400305.

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