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1

Vasant, B. Kadam. "Phytochemical Profile of Trigonella foenum graecum Linn." International Journal of Pharmaceutics & Pharmacology 2, no. 2 (2018): 1–4. https://doi.org/10.31531/2581-3080.1000130.

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<em>The seasonal variation of protein, amino acids and alkaloids has been investigated in leaves, stem, roots and seeds of Trigonella foenum graecum. The leaves of Trigonella foenum graecum showed high level of protein content during summer season (5.131 mg/g dry wt.)&nbsp; than monsoon (4.563 mg/g dry wt.) and winter (4.637 mg/g dry wt.) season. Comparative account of amino acid content of leaves of Trigonella foenum graecum showed higher level in summer season (0.914 mg/g dry wt.) and lowest amount of amino acid content in the leaves during monsoon (0.832 mg/g dry/wt.) season. The leaves of&
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2

Susilawati, Putu, Bagus Komang Satriyasa, and I. Gusti Ayu Widianti. "Pemberian Ekstrak Etanol Biji Klabet (Trigonella foenum-graecum L.) Menurunkan Kualitas Spermatozoa Mencit (Mus musculus) Dewasa Muda." Metamorfosa: Journal of Biological Sciences 9, no. 2 (2022): 318. http://dx.doi.org/10.24843/metamorfosa.2022.v09.i02.p11.

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Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol Biji Klabet (Trigonella foenum-graecum Linn.) dapat menurunkan kualitas spermatozoa mencit (Mus musculus) dewasa muda sebagai bahan kontrasepsi pria alami. Penelitian ini merupakan penelitian eksperimental dengan menggunakan rancangan penelitian post-test only control group design. Sampel penelitian ini terdiri dari 36 ekor mencit (Mus musculus) jantan galur Swiss Webster usia 2-3 bulan dengan berat badan 20-30 gram yang dibagi menjadi dua kelompok secara acak. Kelompok kontrol (P0) diberikan CMC Na 0,3% sebanyak 0,5 ml dan kel
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3

B Kadam, Vasant. "Phytochemical Profile of Trigonella foenum graecum Linn." International Journal of Pharmaceutics & Pharmacology 2, no. 2 (2018): 1–4. http://dx.doi.org/10.31531/2581-3080.1000130.

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4

Thorat, R. M., and D. D. Gaikwad. "Pharmacognostical and Phytophysicochemical investigations of Trigonella foenum – graecum Linn." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 138–45. http://dx.doi.org/10.22270/jddt.v9i3-s.2810.

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Fenugreek (Trigonella foenum-graecum L.), plant is distributed throughout the world and which belongs to the family Fabacecae. The fenugreek seed contains active constituents such as Carbohydrates, Proteins, Alkaloids, Flavonoids, Free amino acids, Saponins, Glycosides, Vitamins, Minerals, Mucilage, Fixed Oils &amp; Volatile Oils etc. It has been commonly used as a traditional food and medicine. Fenugreek is known to have hypoglycemic, and hypocholesterolaemic effects, Anti-inflammatory effects. Fenugreek has potential for curing diseases and also as a source for preparing raw materials of pha
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5

Kapoor*, Madhu Kanta, and Sasikumar S. "Comparative foliar studies in saline sand and fresh water soil - grown Trigonella foenum - graecum Linn. plants." International Journal of Bioassays 6, no. 03 (2017): 5304. http://dx.doi.org/10.21746/ijbio.2017.03.004.

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Vegetable markets in Mumbai sell “methi” at two stages of growth, the full grown vegetative to flowering stage and another at two cotyledonary-leaves stage. The latter are commonly grown in the sandy beaches of Mumbai whereas the former are the regular soil-grown ones. The beach grown Trigonella foenum-graecum L. plants are watered with saline beach- well waters whereas the soil-grown ones are watered with regular fresh water. The research work focused on studying the impact of this difference in growing conditions on many growth parameters, viz., morphology, anatomy and biochemical analyses o
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6

Agustini, Kurnia, Wahono Sumaryono, and R. Micho Widyanto. "Activity of Trigonella foenum-graecum on Some Cell Lines." Indonesian Journal of Cancer Chemoprevention 2, no. 2 (2011): 234. http://dx.doi.org/10.14499/indonesianjcanchemoprev2iss2pp234-241.

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Trigonella foenum-graecum (TFG) is one of medicinal plants contains some steroidal sapogenin such as diosgenin, yamogenin, gitogenin, tigogenin and trigoneoside, also alkaloid trigonellin, which is have many activity as antidiabetic, estrogenic and also as anti cancer. This experiment was done to explore the activity of some extract of TFG on some cell lines such as MCF7 (Human Breast Cancer Cell-line), T47D (Human Breast Cancer Cell-line), PC3 (Human Prostate Cell-line) and SKOV (Human Ovarian Carcinoma Cell-line). This assay was done using MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetraz
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7

Chourasiya, Anand, Rakesh Kumar Sahu, and Mohd Azaz Khan. "Anti-Anemic and Haemopoietic Evaluation of Trigonella foenum-graecum (Fenugreek) in Rodent Model." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 332–37. http://dx.doi.org/10.22270/jddt.v9i4-s.3335.

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The health benefits and medicinal properties of herbal food products are known since antiquity. Fenugreek, Trigonella foenum-graecum Linn (T. foenum-graecum, Fabaceae), a seed spice used to enhance flavor, color and texture of food is employed for medicinal purposes in many traditional systems. Ethno botanical survey of T. foenum-graecum revealed the seeds of the plant to be useful in anemia. The objective of this study was to study the ant-anemic effect of hydroalcoholic extract of seeds of T. foenum-graecum against phenylhydrazine induced anemic rat model. The hydroalcoholic extracts of seed
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8

Nahar, Nilufar, and AKM Ahsan Habib. "Soluble dietary fibers from Trigonella foenum graecum Linn. seed and their structures." Journal of Bangladesh Academy of Sciences 38, no. 1 (2014): 19–26. http://dx.doi.org/10.3329/jbas.v38i1.20201.

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Soluble dietary fibers of Trigonella foenum graecum Linn. seed were isolated and fractionatedinto neutral and acidic parts. Structures of both the fractions were determined by sugar analysis andhigh resolution 2D NMR spectroscopic studies including total correlation (TOCSY) spectroscopy.Main chain of the neutral SDF fraction was found to be a galactomannan composed of mannoseand galactose (~1 : 1.5 ratio) having 1,3-? linkages between each other. Terminal mannose residuewas linked to galactose residue of the main chain at its 4 position by ?-linkage. The acidic SDF wasa rhamnogalacturonan, in
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9

S, Srivatchava, R. Priyadharshini, and Palati Sinduja. "Comparative Study on Effect Of Fenugreek Seed Supplementation On WBC, Platelets Among Females Between 18-20 Years: A Parallel Randomized Clinical Trial." Cuestiones de Fisioterapia 54, no. 3 (2025): 3132–44. https://doi.org/10.48047/jbhwps23.

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Introduction: White blood cells are a heterogenous group of nucleated cells whose normal value is between 4,000-10,000/cubic mm. Fenugreek (Trigonella foenum-graecum Linn.), a short-living annual medicinal plant belonging to the Fabaceae family with different versatile uses such as herb,spice, food and medicine. It is considered to be one of the oldest Ayurvedic and Chinese medicine. Various studies were done to prove the pharmaceutical uses of fenugreek. Inorder to avoid the ill effects of the disorders and their synthetic drugs, the pharmaceutical effects of natural products are studied.
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10

Pundarikakshudu, Kilambi, DeepakH Shah, AashishH Panchal, and GordhanbhaiC Bhavsar. "Anti-inflammatory activity of fenugreek (Trigonella foenum-graecum Linn) seed petroleum ether extract." Indian Journal of Pharmacology 48, no. 4 (2016): 441. http://dx.doi.org/10.4103/0253-7613.186195.

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11

Assad, Tahira, Rafeeq Alam Khan, and Muhammad Ali Rajput. "Effect of Trigonella foenum-graecum Linn. seeds methanol extract on learning and memory." Metabolic Brain Disease 33, no. 4 (2018): 1275–80. http://dx.doi.org/10.1007/s11011-018-0235-1.

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12

Agustini, Kurnia, Firdayani Firdayani, and Churiyah Churiyah. "Cytotoxic Activity on MCF-7 Cells and in Silico Study of Sapogenin Steroids From Trigonella foenum-graecum L." Indonesian Journal of Cancer Chemoprevention 6, no. 1 (2017): 1. http://dx.doi.org/10.14499/indonesianjcanchemoprev6iss1pp1-6.

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Trigonella foenum-graecum (TFG) is one of medicinal plants containing several steroidal sapogenins, such as diosgenin, yamogenin, gitogenin, tigogenin and trigoneoside, and also alkaloid trigonellin and some flavonoids such as vitexin, isovitexin, orientin, isoorientin, which has many activities, such as antidiabetic, estrogenic, and also anticancer. As phytoestrogen, TFG was predicted to have potency as Selective Estrogen Receptor Modulators (SERMs) which is used for hormonal-dependent breast cancer treatment. This experiment was carried out to investigate interaction of some sapogenin steroi
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13

Zahra, Kaenat, Abdullah ., and Razia Shaheen. "Hulba (Trigonella foenum graecum Linn.): the blessed medicinal herb of Unani System of Medicine." American Journal of PharmTech Research 9, no. 6 (2019): 267–77. http://dx.doi.org/10.46624/ajptr.2019.v9.i6.023.

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14

Kasaye, Tamiru. "Utilization of Fenugreek (Trigonella foenum-graecum Linn) to Develop Value Added Biscuits and Breads." European Journal of Nutrition & Food Safety 5, no. 5 (2015): 602–3. http://dx.doi.org/10.9734/ejnfs/2015/20986.

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15

Daman, Janhavi Jatin, Radiya Pacha-Gupta, and Nandita Mangalore. "Maltase Inhibitory Activity of Aqueous Extracts of Zingiber officinale Rosc. and Trigonella foenum-graecum Linn." Pharmacognosy Journal 10, no. 2 (2018): 226–29. http://dx.doi.org/10.5530/pj.2018.2.39.

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16

Suresh, K. Mohankumar, and R. McFarlane James. "Effect of Aqueous Extracts of some Ayurvedic Medicinal Plants on Tissues Involved in Glucose Homeostasis in vitro." International Journal of Diabetology & Vascular Disease Research 3, no. 6 (2015): 105–7. https://doi.org/10.19070/2328-353X-1500021.

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Aqueous extracts of some antidiabetic Ayurvedic plant treatments such as Trigonella foenum-graecum Linn (TFG), Pterocarpus&nbsp;marsupium Roxb (PM), Gymnema sylvestre R.Br (GS) and Curcuma longa Linn (CL) were tested for their biological&nbsp;effects on glucose uptake by mouse muscle tissue and insulin secretion from mouse pancreas under both basal and hyperglycemic culture conditions. The results indicate that none of these treatments have a significant effect on either glucose uptake&nbsp;by muscle or insulin secretion from the pancreas under basal conditions. Under hyperglycemic conditions
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17

John, Biby Sara, Sophia D, Ramamurthy V, and Mathew Joe Prasad. "Chemopreventive Activities of Trigonella foenum graecum Against Hepatocellular Carcinoma Cell Line." International Journal of Zoological Investigations 9, no. 2 (2023): 1188–97. http://dx.doi.org/10.33745/ijzi.2023.v09i02.132.

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18

Hanafi, Noorul Izzati, Noor Hafizoh Saidan, Maizan Mohamed, et al. "REVIEW: ISCHEMIC HEART DISEASE AND THE POTENTIAL ROLE OF FENUGREEK (TRIGONELLA FOENUM GRAECUM LINN.) IN CARDIOPROTECTION." Jurnal Teknologi 84, no. 2 (2022): 183–97. http://dx.doi.org/10.11113/jurnalteknologi.v84.17542.

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Ischemic heart disease, often known as coronary heart disease (CHD), is a term for heart disorders caused by narrowing heart arteries (coronary arteries) that provide blood to the heart's muscles. The body is prone to heart attacks when there is less oxygen supply (hypoxia) to the heart resulting a major cell death in the heart tissues. Cardiovascular disease (CVD) is the leading cause of death worldwide. Over the last few decades, the potential therapeutic effects of herbs and other types of complementary medicines for managing risk factors for CVD have gotten a lot of attention. Fenugreek (T
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19

Osman Magdoleen G, Daffalla H M, Ahmad Magda M M, Ali Kauther Sir el-khatim, Saleh Salma A, and Hamza Abdelhalim A. "Total phenolic content, antioxidant and antimicrobial activities of seeds and callus of Trigonella foenum-graecum Linn." GSC Biological and Pharmaceutical Sciences 10, no. 3 (2020): 001–9. http://dx.doi.org/10.30574/gscbps.2020.10.3.0033.

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20

Pawar, Vinod S., and Shivakumar Hugar. "Adaptogenic activity of Trigonella foenum graecum (Linn) seeds in rodents exposed to anoxia and immobilization stress." Asian Pacific Journal of Tropical Biomedicine 2, no. 1 (2012): S208—S211. http://dx.doi.org/10.1016/s2221-1691(12)60161-0.

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21

Puri, D., K. M. Prabhu, and P. S. Murthy. "Antidiabetic Effect of GII Compound Purified from Fenugreek (Trigonella foenum graecum Linn) Seeds in Diabetic Rabbits." Indian Journal of Clinical Biochemistry 27, no. 1 (2011): 21–27. http://dx.doi.org/10.1007/s12291-011-0151-1.

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22

Osman, Magdoleen G., H. M. Daffalla, Magda M. M. Ahmad, Kauther Sir el-khatim Ali, Salma A. Saleh, and Abdelhalim A. Hamza. "Total phenolic content, antioxidant and antimicrobial activities of seeds and callus of Trigonella foenum-graecum Linn." GSC Biological and Pharmaceutical Sciences 10, no. 3 (2020): 001–9. https://doi.org/10.5281/zenodo.4279455.

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Development of an efficient system for callus induction on different explants of fenugreek. Comparing phenolic, antioxidant and antimicrobial activities of seed and calli of different fenugreek explants. Fenugreek is a well-known medicinal plant for pharmaceutical and nutraceutical properties.&nbsp; For callus induction, three explants were used viz. hypocotyl, root, and cotyledons. The explants were cultured on MS medium supplemented with 2, 4-D, NAA and TDZ in different concentrations (0.5-6 mg/L). Antioxidant activity using DPPH and Folin-ciocalteu assays, and antimicrobial activity of call
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23

John, Biby Sara, Ramamurthy V, and Mathew Joe Prasad. "Anticancer Activities of Trigonella foenum-graecum against Pancreatic Ductal Adenocarcinoma Cell Line." International Journal of Zoological Investigations 10, no. 2 (2024): 1330–34. https://doi.org/10.33745/ijzi.2024.v10i02.135.

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24

Bhandari, Uma, and Parveen Kumar. "Protective effect of Trigonella foenum-graecum Linn. on monosodium glutamate-induced dyslipidemia and oxidative stress in rats." Indian Journal of Pharmacology 45, no. 2 (2013): 136. http://dx.doi.org/10.4103/0253-7613.108288.

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25

Bansode, Twinkle, Amit Gupta, Sushama Chaphalkar, and B. Salalkar. "Integrating In-silico and In-vitro Approaches to Screen the Antidiabetic Drug from Trigonella foenum graecum Linn." International Journal of Biochemistry Research & Review 14, no. 3 (2016): 1–10. http://dx.doi.org/10.9734/ijbcrr/2016/29875.

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26

Premanath, Ramya, N. Lakshmidevi, K. Jayashree, and R. N. Suresh. "Evaluation of anti-diabetic effect of Trigonella foenum graecum Linn. Leaf extract in streptozotocin induced diabetic rats." International Journal of Diabetes in Developing Countries 32, no. 3 (2012): 138–44. http://dx.doi.org/10.1007/s13410-012-0081-3.

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27

Rose, Beena P. K., Anita K. Patel, and Asha K V. "A REVIEW ON METHIKA (TRIGONELLA FOENUM GRAECUM LINN): A WIDELY USED DRUG IN POSTNATAL CARE IN KERALA, INDIA." International Journal of Research in Ayurveda and Pharmacy 11, no. 3 (2020): 61–63. http://dx.doi.org/10.7897/2277-4343.110361.

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28

Bhaumik, C., and P. P. C. Datta. "THE EFFECT OF N, P AND K DEFICIENCY ON TISSUE DIFFERENTIATION AND DIOSGENIN CONTENT IN TRIGONELLA FOENUM-GRAECUM LINN." Acta Horticulturae, no. 188 (June 1986): 221–24. http://dx.doi.org/10.17660/actahortic.1986.188.27.

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29

Kumar, Tarun, PShyamasakhi Devi, Priyotosh Banerjee, and NMeena Devi. "ANTICONVULSANT EFFECT OF ETHANOLIC EXTRACT OF TRIGONELLA FOENUM GRAECUM LINN. AND SODIUM VALPROATE - A COMPARATIVE STUDY IN ALBINO MICE." International Journal of Advanced Research 5, no. 11 (2017): 350–54. http://dx.doi.org/10.21474/ijar01/5776.

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30

Vats, V., J. K. Grover, and S. S. Rathi. "Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats." Journal of Ethnopharmacology 79, no. 1 (2002): 95–100. http://dx.doi.org/10.1016/s0378-8741(01)00374-9.

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31

Singh, M., P. Mahala, T. V. Yadav, and B. L. Kakraliya. "Influence of Brassinolide in Mitigating the Adverse Effect of Drought on Yield Attributes in Fenugreek (Trigonella foenum-graecum Linn) Genotypes." International Journal of Current Microbiology and Applied Sciences 7, no. 06 (2018): 1475–78. http://dx.doi.org/10.20546/ijcmas.2018.706.175.

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32

Hameed, Saleha, Ali Imran, Mehr un Nisa, et al. "Characterization of extracted phenolics from black cumin (Nigella sativa linn), coriander seed (Coriandrum sativum L.), and fenugreek seed (Trigonella foenum-graecum)." International Journal of Food Properties 22, no. 1 (2019): 714–26. http://dx.doi.org/10.1080/10942912.2019.1599390.

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33

Ghayur, Muhammad Nabeel, Mohnad Abdalla, Asaad Khalid, Saeed Ahmad, and Anwarul Hassan Gilani. "Trigonella foenum-graecum Methanolic Extract on Isolated Smooth Muscles and Acetylcholinesterase Enzyme: An In Vitro and Mechanistic In Silico Investigation." BioMed Research International 2022 (April 5, 2022): 1–12. http://dx.doi.org/10.1155/2022/4849464.

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Background and Objective. Trigonella foenum-graecum Linn., also called fenugreek, is a popular medicinal plant cultivated all over the globe. Fenugreek seeds are known for their many medicinal properties. We present our findings on the effect of a 70% aqueous methanolic fenugreek seed extract (Tfg.Cr) on isolated GI smooth muscles (rabbit jejunum and rat ileum) and the effect of extract and its constituent diosgenin on acetylcholinesterase (AChE) enzyme. Results. When tested on the baseline of isolated tissues, Tfg.Cr was devoid of any activity (stimulant or relaxant) till 10 mg/ml. This is an
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Ali, Nada M., Mazin A. Zamzami, and Samir M. Khoja. "Regulation of hepatic and mucosal 6-phosphofructo-1-kinase activity by trigonella foenum-graecum linn (fenugreek) seeds of streptozotocin-induced diabetic rats." Journal of Diabetes Research and Clinical Metabolism 2, no. 1 (2013): 18. http://dx.doi.org/10.7243/2050-0866-2-18.

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35

Nimbalkar, Vikram V., Ravina P. Shelke, Urmila E. Kadu, and Pandurang M. Gaikwad. "PROTECTIVE EFFECT OF DIOSGENIN AGAINST CARBON TETRACHLORIDE AND CISPLATIN INDUCED HEPATOTOXICITY IN RATS." International Journal of Clinical and Biomedical Research 4, no. 3 (2018): 50–56. http://dx.doi.org/10.31878/ijcbr.2018.43.11.

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Background: Activation of hepatic stellate cells (HSC) plays central role in the development of liver fibrosis. In HSC activation, the transforming growth factor-β1 (TGF-β1) is considered to be the main stimuli factor. Diosgenin are the steroidal saponin and found in Trigonella foenum graecum Linn (Fenugreek) and some other species of Dioscorea. Diosgenin attenuates HSC activation by inhibiting transforming growth factor-β. Aim: In present study an attempt was made to explore the effect of diosgenin on liver fibrosis. Methods: Liver fibrosis was induced in rats by carbon tetrachloride (CCl4) 1
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Nursanti, Okta, Dayu Liandra, Ginayanti Hadisoebroto, and Dytha Andri Deswati. "MOLEKULER DOCKING TERHADAP RESEPTOR PEROXISOME PROLIFERATOR-ACTIVED RECEPTOR-GAMMA (PPAR-y) SEBAGAI ANTIDIABETES." Medical Sains : Jurnal Ilmiah Kefarmasian 8, no. 1 (2023): 315–24. http://dx.doi.org/10.37874/ms.v8i1.521.

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Diabetes mellitus (DM) merupakan penyakit kronik yang muncul baik ketika pancreas tidak mampu memproduksi cukup insulin ataupun ketika tubuh tidak dapat menggunakan insulin yang diproduksi secara efektif tanaman atau tumbuhan telah banyak digunakan oleh masyarakat sebagai pencegah serta pengobatan penyakit diabetes dan juga sebagai suplemen kesehatan. Di dalam nya terkandung senyawa-senyawa yang dapat berperan sebagai obat antidiabetes. Salah satu reseptor yang berperan dalam pengobatan diabetes adalah Peroxisome Proliferator-Actived Receptor-Gamma (PPAR-y) yang bertanggung jawab terhadap sens
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37

Journal, Baghdad Science. "Study of Cytotoxic Effect of Aqueous Extract Fenugreek(Trigonella Foenum Graecum L.S) Seeds and The New Complexes of Rh (?) and Pd (?) on Cancer Cell Lines." Baghdad Science Journal 9, no. 2 (2018): 289–95. http://dx.doi.org/10.21123/bsj.9.2.289-295.

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The effect of the aqueous extract of fenugreek seeds (Trigonella Foenum Graecum L.), Rhodium complex (?) with formula [RhL2CLH2O].1 1/2 ETOH and palladium (?) [pdl2].2ETOH,where L=2-hydroxy phenyl piperonalidine was studied on two cancer cell lines. The first cell line was intestine cancer of female albino mice (L20B), the second one was Rhabdomysarcomas (RD)cell line in human. The activity of the new complexes and the aqueous extract was compared to the well-known anticancer drug (cis-platin) by utilizing the in vitro system. The cell lines were treated with four concentrations of cis-platin
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Zahra, Kaenat, Dr Abdull, and Dr Razia Shaheen. "Clinical Efficacy of Hulba (Trigonella foenum graecum Linn.) and Dry Cupping (Hijamat Bila Shurt) in the Management of Primary Dysmenorrhoea (Usre Tams Ibtidae) ’." American Journal of PharmTech Research 9, no. 6 (2019): 175–90. http://dx.doi.org/10.46624/ajptr.2019.v9.i6.014.

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39

Journal, Baghdad Science. "Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines." Baghdad Science Journal 10, no. 2 (2013): 368–76. http://dx.doi.org/10.21123/bsj.10.2.368-376.

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This study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extracts were compared with the known anticancer drug Cis-platinum(Cis-Pt) as a positive control. The phytochemical tests were used for screening the active compounds in plants. The inhibition activity assay was used as a parameter of the cytotoxic effect of these extracts. Cancer cell lines were treated
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40

Hussain, Jinan, Iman Hashim, Farooq Ibrahem Mohammed, Ashgan Salman, and Noora Saad. "Comparison of The Effect of Aqueous Extracts of two Plants, Origanum Vulgare L. and Fenugreek Seeds with Anticancer Drug Cis-Platin on the Growth of Cancer Cell Lines." Baghdad Science Journal 10, no. 2 (2013): 368–76. http://dx.doi.org/10.21123/bsj.2013.10.2.368-376.

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This study involved the effect of the aqueous extracts of two plants, Origanum vulgare L.(1), Trigonella Foenum Graecum L. (Fenugreek) seeds(2) on the growth of cancer cell lines. Rhabdomyo sarcomas (RD) of human cell line and female intestine cells of Albino mice (L20B) in vitro System. These extracts were compared with the known anticancer drug Cis-platinum(Cis-Pt) as a positive control. The phytochemical tests were used for screening the active compounds in plants. The inhibition activity assay was used as a parameter of the cytotoxic effect of these extracts. Cancer cell lines were treated
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Tiwari, Gaurav, and Ruchi Tiwari. "Assessment of Nutraceutical Potential of Herbs for Promoting Hair Growth: Formulation Considerations of Herbal Hair Oil." Open Dermatology Journal 15, no. 1 (2021): 78–83. http://dx.doi.org/10.2174/1874372202115010078.

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Background: Hair loss is a relatively common occurrence that causes concern in people of all ages. In most cases, hair loss is permanent, but it can lead to alopecia. Hair root activation is necessary to improve hair development and prevent hair loss. Herbal cosmetics are increasingly widely used by the general public due to the concept of fewer adverse effects and a higher level of safety and security. Objective: The primary goal of this study is to prepare and evaluate herbal hair oil made from fresh components of various plants. Methods: Herbs were acquired from Pranveer Singh Institute of
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Agustini, Kurnia, Michael Wink, Wahono Sumaryono, Frans Suyatna, and Nurjati Chairani Siregar. "TRIGONELLA FOENUM-GRAECUM L. EXHIBITS ESTROGENIC EFFECT THROUGH PRESENILIN 2 GENE EXPRESSION IN THE BREAST CANCER CELL LINE MCF-7." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 438. http://dx.doi.org/10.22159/ajpcr.2018.v12i1.29340.

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Objective: The objective of this study is to investigate the estrogenic and antiestrogenic activity of Fenugreek seeds, Trigonella foenum-graecum L. in the estrogen-dependent breast cancer cell line, MCF-7, including its effect on the expression of estrogen-dependent presenilin 2 (pS2) gene.Methods: An activity guided fractionation was carried out with extracts from fenugreek seeds in MCF-7 cells. Cytotoxic activity assays were conducted with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay. Most fractions were also tested also tested in media with estradiol 10 nM We also analy
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Wink, Michael, Wahono Sumaryono, Frans Suyatna, and Nurjati Chairani Siregar. "TRIGONELLA FOENUM-GRAECUM L. EXHIBITS ESTROGENIC EFFECT THROUGH PRESENILIN 2 GENE EXPRESSION IN THE BREAST CANCER CELL LINE MCF-7." Asian Journal of Pharmaceutical and Clinical Research 12, no. 1 (2019): 438. http://dx.doi.org/10.22159/ajpcr.2019.v12i1.29340.

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Objective: The objective of this study is to investigate the estrogenic and antiestrogenic activity of Fenugreek seeds, Trigonella foenum-graecum L. in the estrogen-dependent breast cancer cell line, MCF-7, including its effect on the expression of estrogen-dependent presenilin 2 (pS2) gene.Methods: An activity guided fractionation was carried out with extracts from fenugreek seeds in MCF-7 cells. Cytotoxic activity assays were conducted with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assay. Most fractions were also tested also tested in media with estradiol 10 nM We also analy
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44

Kartal, Sevtap, Zeynep Baturay, and Lale Efe. "Effect of Planting Times on the Yield and Quality of Fenugreek (Trigonella Foenum-Graecum L.) Under the Conditions of Kahramanmaraş." Turkish Journal of Agriculture - Food Science and Technology 11, no. 2 (2023): 296–302. http://dx.doi.org/10.24925/turjaf.v11i2.296-302.5662.

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This study was performed in the 2013-2014 cultivation season with the purpose of determining the most suitable planting season of fenugreek under the ecological conditions of Kahramanmaraş. The trial was established in two different cultivation periods as winter and spring at the Eastern Mediterranean Transition Zone Agricultural Research Station in according to factorial randomized block design with three replications. In the study, the Gürarslan fenugreek variety as well as Candicate Line-1 and Genotype-1 fenugreek genotypes were used as material. In the study, features such as plant height,
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Chadchan, Kailash S., Swastika N. Das, Jameel G. Jargar, and Kusal K. Das. "A Comparative Study on Anti-diabetic Effects of Aqueous Trigonella foenum graecum, Hibiscus cannabinus Linn, and Cicer arietinum extracts on Alloxan Induced Diabetic Male Albino Rats." Journal of Young Pharmacists 9, no. 2 (2017): 230–33. http://dx.doi.org/10.5530/jyp.2017.9.45.

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İnanan, Burak Evren, and Mahir Kanyılmaz. "Kakule, Ayçiçeği ve Çemen Otu Tohumları Ekstraktlarının Sazan Balığı (Cyprinus carpio L.) Sperm Motilitesine ve Oksidatif Strese In Vitro Etkileri." Turkish Journal of Agriculture - Food Science and Technology 8, no. 1 (2020): 214. http://dx.doi.org/10.24925/turjaf.v8i1.214-219.2974.

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The aim of the present study is to assess the effects Fenugreek (Trigonella foenum-graecum, Fabaceae), sunflower (Helianthus annuus, Asteraceae), green cardamom (Elettaria cardamomum, Zingiberaceae) and seed extracts, which they belonged to three different plant families, on common carp (Cyprinus carpio L.) spermatozoa motility parameters and oxidative stress conditions. For this reason, sperm samples treated with seed extracts at the ratios of 0.1%, %0.5, 1%, and 2%, were incubated at 4°C and sampled at 2nd and 48th hours. Among sperm motility parameters, curvilinear velocity (VCL), average p
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Gupta, Piyush, Nagendra Chauhan, and Anupam Pathak. "Effect of <i>Trigonella foenum-graecum</i> Linn. (seeds) and <i>Butea monosperma</i> Lam. (flowers) on chemotherapy-induced alopecia." Spatula DD - Peer Reviewed Journal on Complementary Medicine and Drug Discovery 3, no. 3 (2013): 121. http://dx.doi.org/10.5455/spatula.20130909073404.

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Rehan S., Ahmad, Dutta Sumana, and Shamsi Intikhab Alam. "A Systematic Investigation of Trigonelline, Diosgenin, Protodioscin, and Dioscin from Trigonella foenum-graecum (fenugreek seeds) has Anti-cancer and Antioxidant Properties Without Side Effects." International Journal of Zoological Investigations 08, no. 02 (2022): 404–18. http://dx.doi.org/10.33745/ijzi.2022.v08i02.050.

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Systematic review and meta-analysis criteria were used to plan and conduct this systematic review (PRISMA). Different literature of reviews explicit that Fibers, flavonoids, polysaccharides, and saponins are the principal chemical components of Trigonella foenum-graecum. Some of the components may have mitogenic actions, which result in immune-competent cells being restored. Some of these ingredients are also antioxidants and may have immune-stimulant characteristics. In vitro, the extract from the seeds of the fenugreek seed was found to be cytotoxic to numerous cancers, including T-cell lymp
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Naik, Archana, Chhaya Gadgoli, Nikita Patil, and Ruchira Salunkhe. "Simultaneous Estimation for Diosgenin, Charantin and Hydroxychalcone from Herbal Antidiabetic Formulation using Validated HPTLC Method." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 03 (2023): 612–17. http://dx.doi.org/10.25258/ijpqa.14.3.26.

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Most antidiabetic polyherbal preparations contain Trigonella foenum-graecum, Momordica charantia and Cinnamomum zeylanicum as active components. Although all ingredients are popular as antidiabetic agents, but the analytical method is not available for simultaneous estimation of marker compounds from herbal formulations due to several challenges. Hence, the HPTLC method was developed for simultaneous estimation of three active phytoconstituents viz. diosgenin, charantin and hydroxychalcone in polyherbal formulation. The stationary phase of the optimized HPTLC method is silica gel 60 GF254 and
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Paul, Santanu, and Debarupa Hajra. "Study of glucose uptake enhancing potential of fenugreek (Trigonella foenum graecum) leaves extract on 3T3 L1 cells line and evaluation of its antioxidant potential." Pharmacognosy Research 10, no. 4 (2018): 347. http://dx.doi.org/10.4103/pr.pr_50_18.

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