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Journal articles on the topic 'Trihexyphenidyl – analysis'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Priescisila, Indri Riza, and Mahmudah Mahmudah. "Hubungan Faktor Lingkungan dengan Penggunaan Trihexyphenidyl pada Remaja di BNN Kota Surabaya." Jurnal Biometrika dan Kependudukan 5, no. 1 (2017): 70. http://dx.doi.org/10.20473/jbk.v5i1.2016.70-79.

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Drugs abuse is increase every years. One of the type of medicines that often abused by teenager is trihexyphenidyl or commonly called pills koplo. The use of a drug was infl uenced some of factors, such as environment (schools, family, and their peers). The purpose of this research to fi nd out the relationship between environment factors with the use of trihexyphenidyl by teenager in BNN Surabaya City. The research was observational research by design cross sectional. Technique sampling the research is simple random sampling, from teenager was 12-21 years and used trihexyphenidyl who performs

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2

Radić, Josip, Maša Buljac, Boštjan Genorio, Ema Gričar, and Mitja Kolar. "A Novel Reduced Graphene Oxide Modified Carbon Paste Electrode for Potentiometric Determination of Trihexyphenidyl Hydrochloride in Pharmaceutical and Biological Matrices." Sensors 21, no. 9 (2021): 2955. http://dx.doi.org/10.3390/s21092955.

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A novel promising carbon paste electrode with excellent potentiometric properties was prepared for the analysis of trihexyphenidyl hydrochloride (THP), the acetylcholine receptor and an anticholinergic drug in real samples. It contains 10.2% trihexyphenidy-tetraphenylborate ionic pair as the electroactive material, with the addition of 3.9% reduced graphene oxide and 0.3% of anionic additive into the paste, which consists of 45.0% dibutylphthalate as the solvent mediator and 40.6% graphite. Under the optimized experimental conditions, the electrode showed a Nernstian slope of 58.9 ± 0.2 mV/dec

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3

Martin-Molins, C., P. Sibille, N. Milan, and M. H. Ghysel-Laporte. "Hair analysis report: Trihexyphenidyl, an antiparkinsonian agent facilitating assaults." Toxicologie Analytique et Clinique 31, no. 2 (2019): S82—S83. http://dx.doi.org/10.1016/j.toxac.2019.03.132.

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4

Dinakaran, Sathis Kumar, Santhos Kumar, David Banji, Harani Avasarala, and Venkateshwar Rao. "Formulation and evaluation of bi-layer floating tablets of ziprasidone HCl and trihexyphenidyl HCl." Brazilian Journal of Pharmaceutical Sciences 47, no. 3 (2011): 545–53. http://dx.doi.org/10.1590/s1984-82502011000300012.

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The purpose of this research study was to establish ziprasidone HCl NR 40 mg and trihexyphenidyl HCl SR 4mg in the form of bi-layer sustained release floating tablets. The tablets were prepared using sodium HPMC K4M / HPMC K15M as bio-adhesive polymers and sodium bicarbonate acting as a floating layer. Tablets were evaluated based on different parameters such as thickness, hardness, friability, weight variation, in vitro dissolution studies, content of active ingredient and IR studies. The physico-chemical properties of the finished product complied with the specifications. In vitro release fr

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5

Romeo, Domenico M., Alessandro Specchia, Alfonso Fasano, et al. "Treatment of Dystonia Using Trihexyphenidyl in Costello Syndrome." Brain Sciences 10, no. 7 (2020): 450. http://dx.doi.org/10.3390/brainsci10070450.

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Costello syndrome (CS), a rare syndrome with multisystemic involvement inherited as a dominant trait, is characterized by developmental delay, coarse facial appearance, cardiac defects including hypertrophic cardiomyopathy, skin abnormalities, brain complications, and a predisposition to certain malignancies. The musculoskeletal system is particularly affected in CS, with peculiar orthopedic anomalies that impact posture and gait. Dystonia has been recently documented to contribute to abnormal postures and musculoskeletal anomalies characterizing CS, suggesting the possible use of pharmacologi

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6

Shetti, P., and A. Venkatachalam. "Stability Indicating HPLC Method for Simultaneous Quantification of Trihexyphenidyl Hydrochloride, Trifluoperazine Hydrochloride and Chlorpromazine Hydrochloride from Tablet Formulation." E-Journal of Chemistry 7, s1 (2010): S299—S313. http://dx.doi.org/10.1155/2010/529386.

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A new, simple, precise, rapid, selective and stability indicating reversed-phase high performance liquid chromatographic (HPLC) method has been developed and validated for simultaneous quantification of trihexyphenidyl hydrochloride, trifluoperazine hydrochloride and chlorpromazine hydrochloride from combined tablet formulation. The method is based on reverse-phase using C-18 (250×4.6) mm, 5 μm particle size column. The separation is achieved using isocratic elution by methanol and ammonium acetate buffer (1% w/v, pH 6.5) in the ratio of 85:15 v/v, pumped at flow rate 1.0 mL/min and UV detecti

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7

Ben-Pazi, Hilla. "Trihexyphenidyl Improves Motor Function in Children with Dystonic Cerebral Palsy: A Retrospective Analysis." Journal of Child Neurology 26, no. 7 (2011): 810–16. http://dx.doi.org/10.1177/0883073810392582.

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8

Rahaya, Anggie, and Noor Cahaya. "STUDI RETROSPEKTIF PENGGUNAAN TRIHEXYFENIDIL PADA PASIEN SKIZOFRENIA RAWAT INAP YANG MENDAPAT TERAPI ANTIPSKOTIK DI RUMAH SAKIT JIWA SAMBANG LIHUM." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 2, no. 2 (2016): 124–31. http://dx.doi.org/10.22487/j24428744.2016.v2.i2.5986.

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Trihexyphenidyl (THP) is used to treat symptoms of Parkinson's disease or involuntary movements due to the side effects of certain psychiatric drugs. It can also decrease other side effects such as muscle stiffness/rigidity (extrapyramidal syndrome or EPS). EPS were an unavoidable consequence of effective antipsychotic therapy. EPS reduce beneficial effects of antipsychotic treatment on the negative, cognitive, and mood symptom domains, while increasing the risk of tardive dyskinesia and reducing compliance. The purpose of this research was to analyze the percentage use of THP and the pattern

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9

Jawanjal, Pradip M., Pritam B. Patil, Jayesh Patil, Mrunal Waghulde, and Jietndra B. Naik. "Development of Graphene Oxide-Trihexyphenidyl Hydrochloride Nanohybrid and Release behavior." Current Environmental Engineering 6, no. 2 (2019): 134–40. http://dx.doi.org/10.2174/2212717806666190313153239.

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Background: The demand of an efficient nanocarrier in drug delivery, graphene and its derivatives are emerging as a rising star due to its remarkable chemical and structural properties. Objective: Graphene oxide (GO) has high surface area and ability to load high amount of aromatic drugs. Hence, the objective of the research was to load Trihexyphenidyl hydrochloride (THP), antiparkinsonian drug on GO ultrasonically by π-π stacking interaction. Methods: GO was synthesized by the modified Hummer method. The conjugation of GOTHP was generated by using Design-Expert Software and release study of G

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10

Vargas-Toscano, Andres, Dilaware Khan, Ann-Christin Nickel, et al. "Robot technology identifies a Parkinsonian therapeutics repurpose to target stem cells of glioblastoma." CNS Oncology 9, no. 2 (2020): CNS58. http://dx.doi.org/10.2217/cns-2020-0004.

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Aim: Glioblastoma is a heterogeneous lethal disease, regulated by a stem-cell hierarchy and the neurotransmitter microenvironment. The identification of chemotherapies targeting individual cancer stem cells is a clinical need. Methodology: A robotic workstation was programmed to perform a drug concentration to cell-growth analysis on an in vitro model of glioblastoma stem cells (GSCs). Mode-of-action analysis of the selected top substance was performed with manual repetition assays and acquisition of further parameters. Results: We identified 22 therapeutic potential substances. Three suggeste

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11

Sidharta, Emilia, Ivon Sindu Wijaya, and Hanny Cahyadi. "Confusion, difficulty concentrating, and slow response induced by ropinirole therapy in an elderly patient with secondary Parkinsonism: a case report." Jurnal Ilmiah Farmasi 16, no. 2 (2020): 112–17. http://dx.doi.org/10.20885/jif.vol16.iss2.art3.

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Background: Ropinirole is a therapy that is widely used in patients with Parkinson's disease or Restless Leg Syndrome (RLS). Some research journals show that the long-term use of ropinirole can cause side effects. But unfortunately, there are no published studies from Indonesia that show the side effects of ropinirole.. Objective: To report a case of several side effects induced by ropinirole therapy Method : Assessment methods used were time series data collection followed by causality analysis using Naranjo Scale. Results: This case reports several side effects such as confusion, difficulty

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12

YOKOGAWA, KOICHI, EMI NAKASHIMA, FUJIO ICHIMURA, and TSUKINAKA YAMANA. "Simultaneous microdetermination of biperiden, haloperidol, and trihexyphenidyl in plasma and its application to pharmacokinetic analysis after concomitant intravenous administration of the drugs to rabbits." CHEMICAL & PHARMACEUTICAL BULLETIN 33, no. 10 (1985): 4581–86. http://dx.doi.org/10.1248/cpb.33.4581.

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13

Khalilova, N. Sh, N. V. Korableva, V. A. Vetrova, M. U. Abdullayeva, and Z. U. Usmonaliyeva. "EXPERT RESEARCH OF MICROQUANTITIES NARCOTIC, PSYCHOTROPIC SUBSTANCES AND PRECURSORS." Theory and Practice of Forensic Science and Criminalistics 18 (December 26, 2018): 332–51. http://dx.doi.org/10.32353/khrife.2018.38.

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While investigating and prosecuting criminal cases related to illegal drug trade, psychotropic substances and precursors, microobjects found at the scene of crime, as well as on items related to a crime and its participants, assume ever greater evidentiary. In expert practice, narcotic drugs and psychotropic substances often appear as research objects, that are rarely individual compounds. At that greatest difficulties arise while research of substances that are multicomponent systems and mixtures containing a large number of impurity and ballast substances, as well as low concentrations of ac

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14

Munjely, Elza Joy, Bindu Latha Nair R., and Varghese P. Punnoose. "Drug utilization pattern in Schizophrenia." International Journal of Basic & Clinical Pharmacology 8, no. 7 (2019): 1572. http://dx.doi.org/10.18203/2319-2003.ijbcp20192652.

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Background: Pharmacotherapy is the mainstay of treatment in schizophrenia. The economic impact of this illness is wide ranging, long lasting and huge. The emergence of newer antipsychotics has changed the prescribing pattern. Purpose of this study is to determine the prescription pattern of antipsychotic drugs and to analyse the drug utilization in patients with schizophrenia based on WHO prescribing indicators.Methods: A descriptive study was conducted for a period of 1-year duration at inpatient Department of Psychiatry of a Government Medical College in Kerala, India among 230 schizophrenic

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15

You, Peng, Julie Strychowsky, Karan Gandhi, and Breanna A. Chen. "Anticholinergic treatment for sialorrhea in children: A systematic review." Paediatrics & Child Health, August 27, 2021. http://dx.doi.org/10.1093/pch/pxab051.

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Abstract Background Sialorrhea in children can be associated with adverse physical and social effects. Treatment using anticholinergic medications has been shown to offer symptomatic relief, but there is no consensus regarding which treatment is the most efficacious. Objective To examine the effectiveness of anticholinergic medications for sialorrhea in children. Methods A systematic review was carried out in Medline, EMBASE, Cochrane, Scopus, and the Web of Science from inception until April 29, 2020. Studies reporting original data on the efficacy of anticholinergic medications in the manage

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