Relevant bibliographies by topics / Trihydroxyflavone

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Trihydroxyflavone'

Author: Grafiati
Published: 5 June 2025
Last updated: 15 July 2025

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Journal articles on the topic "Trihydroxyflavone"

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Lotulung, Puspa D. N., Sofa Fajriah, Andini Sundowo, and Euis Filaila. "ANTI DIABETIC FLAVANONE COMPOUND FROM THE LEAVES OF Artocarpus communis." Indonesian Journal of Chemistry 9, no. 3 (2010): 505–8. http://dx.doi.org/10.22146/ijc.21524.

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The Flavanone compound with anti diabetic activity was isolated from ethyl acetate extract of Artocarpus communis leaves using column chromatography techniques. The structure of the flavanone compound was elucidated on the basic of spectroscopic evidence and comparison to published values. This compound, 8-geranyl-4,5,7-trihydroxyflavone, showed strong anti diabetic activity on α-glucosidase inhibition assay with IC50 18.120 µg mL-1. Keywords: Artocarpus communis, 8-geranyl-4,5,7-trihydroxyflavone, anti diabetic activity
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Wang, Qing-Hu, Jie-Si Wu, Rong-Jun Wu, Na-Ren-Chao-Ke-Tu Han, and Na-Yin-Tai Dai. "Anti-inflammatory effect and isolation of phenylethanoid and acylated flavone glycosides from Panzeria alaschanica." Zeitschrift für Naturforschung B 70, no. 6 (2015): 379–84. http://dx.doi.org/10.1515/znb-2014-0253.

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AbstractThe phytochemical study of the EtOAc extract from Panzeria alaschanica resulted in the isolation of two new acylated flavone glycosides, 5,7,4′-trihydroxyflavone-7-O-(6″-O-[E]-coumaroyl)-β-glucopyranoside (1) and 5,7,4′-trihydroxyflavone-7-O-(2″,6″-O-[E]-dicoumaroyl)-β-glucopyranoside (2), as well as of a known phenylethanoid (verbascoside, 3). The structure of the isolated compounds was elucidated by spectroscopic methods, including ultraviolet spectrophotometry, infrared absorption spectroscopy, electrospray ionization mass spectrometry and 1D nuclear magnetic resonance spectroscopy,
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Dung, Nguyen Thi, Pham Thi Ninh, Nguyen Thi Luu, et al. "Phytochemical study of Euphorbia cyathophora collected in Dan Phuong, Hanoi and its antidengue activity against DENV1‐4 virus serotypes." Vietnam Journal of Chemistry 61, no. 3 (2023): 371–77. http://dx.doi.org/10.1002/vjch.202300123.

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AbstractThe ethanol extract from the leaves and twigs of Euphorbia cyathophora showed antiviral activity against four dengue virus serotypes (DENV1‐4), with PRNT50 values of 15.625‐62.5 μg/mL. Eight compounds including germanicol acetate (1), cymbopogone (2), 1‐heptacosanol (3), ethyl α‐L‐arabinofuranoside (4), quercetin (5), 3‐acetoxy‐5,7,3’,4’‐tetrahydroxyflavone (6), 3‐acetoxy‐5,7,4’‐trihydroxyflavone (7), 4’‐acetoxy‐3,5,7‐trihydroxyflavone (8) were isolated from this extract. Compounds 2‐8 were isolated for the first time from Euphorbia cyathophora. Antiviral activity evaluation of compoun
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Gupta, Anusha, Shiv Verma, and Sanjay Gupta. "Abstract 962: Activation of natural killer cells by small molecule inhibits growth of BCG-resistant bladder cancer cells." Cancer Research 85, no. 8_Supplement_1 (2025): 962. https://doi.org/10.1158/1538-7445.am2025-962.

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Abstract Bacillus Calmette-Guérin (BCG) is the standard treatment for non-muscle invasive bladder cancer (NMIBC) patients, but resistance declines its efficacy, emphasizing the need for alternative therapies. BCG therapy triggers a specific cytotoxic immune response by activating and expanding CD56/natural killer (NK) cells and T cells, which effectively target and eliminate bladder cancer cells. This priming of NK and T cells by BCG leads to the release of cytokines such as interferon-gamma (IFNγ) and tumor necrosis factor-alpha (TNFα), which stimulate adaptive immunity and enhance tumor cell
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Gabrielska, Janina, Jan Oszmiańsk, Romuald Żyłka, and Małgorzata Komorowska. "Antioxidant Activity of Flavones from Scutellaria baicalensis in Lecithin Liposomes." Zeitschrift für Naturforschung C 52, no. 11-12 (1997): 817–23. http://dx.doi.org/10.1515/znc-1997-11-1215.

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Abstract Trihydroxyflavones of Scutellaria baicalensis, Antioxidant Activity, Liposome, Peroxidation, MDA The antioxidant effect of a trihydroxyflavone extract from Scutellaria baicalensis on oxida­ tion induced by ultraviolet light, was studied with phosphatidylcholine liposome membrane. Also, as standards, the antioxidative activity of baicalin, wogonin, baicalein and butylated hydroxytoluene (BHT) was investigated. Comparison of the protective effects of thecom­pounds studied against photoinduced lipid peroxidation in lecithin liposome membranes showed that: (1) the inhibitory effect of tho
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Tomás-Lorente, Francisco, Manuela M. Garcia-Grau, and Francisco A. Tomás-Barberán. "Flavonoids from Vicia faba Seed Exudates." Zeitschrift für Naturforschung C 45, no. 9-10 (1990): 1070–72. http://dx.doi.org/10.1515/znc-1990-9-1022.

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Abstract From the seed exudates of Vicia faba L. (cv. Muchamiel) the flavonoid aglycones 7,3′,4′-trihydroxyflavone, 7,4′-dihydroxyflavone, quercetin and kaempferol, and the flavonoid glycosides quercetin 7-glucoside and kaempferol 7-glucoside were identified. This is the first time that the flavonoids present in Vicia seed exudates are described. The study of the flavonoids present in legume seed and root exudates is especially important since these substances may act as chemical signals activating or inhibiting Rhizobium nodulation genes. In fact, the activating effect on Rhizobium nod genes
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Avdeeva, Elena, Elvira Shults, Marina Skorokhodova, et al. "Flavonol Glycosides from Saussurea controversa and Their Efficiency in Experimental Osteomyelitis." Planta Medica International Open 5, no. 01 (2018): e24-e29. http://dx.doi.org/10.1055/s-0044-100799.

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AbstractFive flavonoids were isolated from leaves of Saussurea controversa, one new flavonoid (5), three described for the first time from the genus Saussurea (1, 2, and 4), and one described previously (3). A number of flavonol glycosides can be easily isolated from the butanol fraction of the ethanol extract from S. controversa. As a result of separating these using column chromatography on silica gel and microcrystalline cellulose, five glycosides of quercetin were isolated in the proportional relationship of 2 (1): 8 (2): 10 (3): 1 (4): 4 (5). The structure of these substances was determin
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Zheng, Hongling, Xin Yang, Qiuyu Zhang, Joanne Yi Hui Toy, and Dejian Huang. "Food Grade Synthesis of Hetero-Coupled Biflavones and 3D-Quantitative Structure–Activity Relationship (QSAR) Modeling of Antioxidant Activity." Antioxidants 14, no. 6 (2025): 742. https://doi.org/10.3390/antiox14060742.

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Biflavonoids are a unique subclass of dietary polyphenolic compounds known for their diverse bioactivities. Despite these benefits, these biflavonoids remain largely underexplored due to their limited natural availability and harsh conditions required for their synthesis, which restricts broader research and application in functional foods and nutraceuticals. To address this gap, we synthesized a library of rare biflavonoids using a radical–nucleophile coupling reaction previously reported by our group. The food grade coupling reaction under weakly alkaline water at room temperature led to iso
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Wu, Baojian, Shuxing Zhang, and Ming Hu. "Evaluation of 3,3′,4′-Trihydroxyflavone and 3,6,4′-Trihydroxyflavone (4′-O-Glucuronidation) as the in Vitro Functional Markers for Hepatic UGT1A1." Molecular Pharmaceutics 8, no. 6 (2011): 2379–89. http://dx.doi.org/10.1021/mp200300w.

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Jaipetch, Thaworn, Sakchai Hongthong, Samreang Bunteang, et al. "A New Ellagic Acid From the Leaves and Twigs of Irvingia malayana." Natural Product Communications 14, no. 5 (2019): 1934578X1984816. http://dx.doi.org/10.1177/1934578x19848164.

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A phytochemical investigation of the leaves and twigs of Irvingia malayana led to the isolation of a new 3,3′,4′-tri- O-methylellagic acid-6″-acetoxy-4- O-β-glucoside (1), along with 3,3′,4′-tri- O-methylellagic acid (2), 3,3′-di- O-methylellagic acid-4- O-β-xyloside (3), 3,3′,4′-tri- O-methylellagic acid-4-β -O-glucoside (4), friedelin (5), friedelinol (6), methyl-3,4,5-trihydroxybenzoate (7), 5,7,4′-trihydroxyflavone-8- C-β-glucopyranoside (8), 5,7,3′,4′-tetrahydroxyflavone-8- C-β-glucopyranoside (9), and 5,3′,4′-trihydroxyflavone-6- C-β-glucopyranoside (10). Their structures were elucidated
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Dissertations / Theses on the topic "Trihydroxyflavone"

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Huang, Kai-ming, and 黃凱民. "In vitro anti-inflammatory effect of 4’,5,7-Trihydroxyflavone in the Helicobacter pylori-infected gastric adenocarcinoma cells." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/y6m95m.

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碩士<br>國立中興大學<br>食品暨應用生物科技學系所<br>99<br>Helicobacter pylori has been classified as a group I carcinogen by WHO in 1994. Cag A+ H. pylori infection results in serious gastric epithelial cell inflammation, atrophic gastritis, and then progresses to gastric cancer. 4’,5,7- trihydroxyflavone, one of flavonoids, abounds in fruits and vegetables, especially in basil, cilantro, and parsley. As reported, 4’,5,7-trihydroxyflavone exhibited anti-inflammatory, anti-cancer, and anti-oxidative activities. In this study, we investigated in vitro effect of 4’,5,7- trihydroxyflavone on the H. pylori-induced inf
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Wang, An-Ming, and 王安民. "The regulatory effects of the 5,7,2’-trihydroxyflavone and 5,7-dimethoxyflavone on the endogenous CBF1-dependent Notch signaling." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/55207611246335526017.

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碩士<br>臺北醫學大學<br>細胞及分子生物研究所<br>95<br>Notch signal pathway plays the critical roles in cell proliferation, differentiation, and apoptosis. In the prevailing model for Notch signaling, the activated Notch receptors enhance the expression of their target genes via both CBF1-dependent and -independent pathways. Deregulated expression of Notch receptors, ligands, and their targets is observed in numerous malignancies. Recently, the platform to screen the drugs modulating the endogenous Notch signal pathway had been established. In the present study, 5,7,2’-trihydroxyflavone and 5,7-dimethoxyflav
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Liu, Pi-Ying, and 劉璧瑩. "Relaxant effects of 3,7,4'-Trihydroxyflavones in Isolated Guinea Pig Trachea and Their Structure-Activity Relationship." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/53947777070911075929.

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碩士<br>台北醫學大學<br>醫學研究所<br>83<br>Fisetin, kaempferol, quercetin, myricetin and morin are 3,7,4'-trihydroxyflavone derivatives. Fisetin, kaempferol and quercetin dose-dependently relaxed histamine (30 μM)-, carbachol(0.2 μM) -and isotonic KCl(17.5 mM)-induced precontractions in isolated guinea-pig trachea. It showed the ability of kaempferol or quercetin on tracheal relaxation was less than that of fisetin. but larger than that of myricetin or morin, as a result of comparison among their IC50 values. It shows if the proton at position of 5, 2' or 5' is substituted by OH group, the relaxant ac
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Book chapters on the topic "Trihydroxyflavone"

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"3,7,4′-Trihydroxyflavone." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_275.

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"Genistein (4,5,7-trihydroxyflavone)." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_6744.

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"Baicalin (5,6,7-Trihydroxyflavone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_259.

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"Norwogonin (5,7,8-Trihydroxyflavone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_260.

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"Apigenin (5,7,4′-Trihydroxyflavone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_262.

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"5,7,2′-Trihydroxyflavone (2′-Hydroxychrysin)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_261.

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"3′,4′,7-Trihydroxyflavone." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_263.

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"5,8,2′-Trihydroxyflavone-7-O-glucuronopyranoside." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_397.

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"5,6,2′-Trihydroxyflavone-7-O-glucuronide (Ikonnikoside I)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_392.

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"Dihydrobaicalein (5,6,7-Trihydroxyflavanone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0535-1_525.

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Conference papers on the topic "Trihydroxyflavone"

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Santos, Isabela, Hélio M. T. Albuquerque, Artur M. S. Silva, Eduarda Fernandes, and José Miguel P. Ferreira de Oliveira. "In Vitro Cytotoxicity of 7,3′,4′-Trihydroxyflavones in Lung Fibroblasts." In ECMC 2022. MDPI, 2022. http://dx.doi.org/10.3390/ecmc2022-13254.

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