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Journal articles on the topic 'Triphala'

Author: Grafiati

Published: 3 June 2025

Last updated: 19 July 2025

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1

Agrawal, Isha. "Evaluation of Triphala Churna by different physicochemical parameters." African Journal of Biological Sciences 6, Si3 (2024): 650–58. http://dx.doi.org/10.48047/afjbs.6.si3.2024.650-658.

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Triphala, a revered herbal blend within Ayurvedic tradition, has attracted widespread interest for its multifaceted roles in promoting digestive health, detoxification, and overall well- being, alongside its prevalent inclusion in diverse Ayurvedic formulations. This study undertakes a detailed examination of individual Triphala fruit and Triphala Churna, employing a range of pharmaceutical parameters to evaluate its quality, safety, and potential health benefits comprehensively. Through scrutiny of key parameters such as phytochemical composition, physical and chemical properties, and microbi

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2

Panya, Aussara, Kanyaluck Jantakee, Suthida Punwong, et al. "Triphala in Traditional Ayurvedic Medicine Inhibits Dengue Virus Infection in Huh7 Hepatoma Cells." Pharmaceuticals 14, no. 12 (2021): 1236. http://dx.doi.org/10.3390/ph14121236.

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Traditional Triphala (three fruits), consisting of Phyllanthus emblica, Terminalia chebula, and Terminalia bellirica, presents a broad range of biological activities. However, its ability to inhibit dengue virus (DENV) infection has not been reported yet. Herein, the authors investigated the efficiency of three different Triphala formulations and its individual extract constituents to inhibit DENV infection. Treatment with T. bellirica extract or Triphala formulated with a high ratio of T. bellirica extract showed remarkable efficiency in significantly lowering DENV infection in Vero cells. Th

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3

kaur, Paramjeet, Amit Kumar Shukla, and Archna Mishra. "Role of Triphalaand Madhuin Oral Hygiene:A Clinical Study." International Research Journal of Ayurveda & Yoga 05, no. 08 (2022): 70–80. http://dx.doi.org/10.47223/irjay.2022.5809.

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Introduction: Dental caries and periodontal diseases are among the most important global oral health problems. In Ayurveda, Katu, Tikta and Kashaya Rasas are described for Dantadhawana. Most of the products available in the market are sweet in taste which favor the growth bacteria in of oral cavity whereas the Rasas mentioned in Ayurveda are supposed to suppress the growth of bacterial activity and resulting adverse effects on gums and teeth, thus the proposed formulation (Triphala, Madhu) is supposed to promote oral hygiene and restrict chances of gum and teeth disorders. Materials and method

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Phimarn, Wiraphol, Bunleu Sungthong, and Hiroyuki Itabe. "Effects of Triphala on Lipid and Glucose Profiles and Anthropometric Parameters: A Systematic Review." Journal of Evidence-Based Integrative Medicine 26 (January 1, 2021): 2515690X2110110. http://dx.doi.org/10.1177/2515690x211011038.

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Aim. The efficacy of triphala on lipid profile, blood glucose and anthropometric parameters and its safety were assessed. Methods. Databases such as PubMed, ScienceDirect, Web of Science, and Thai Library Integrated System (ThaiLIS) were systematically searched to review current evidence of randomized controlled trials (RCT) on triphala. RCTs investigating the safety and efficacy of triphala on lipid profile, blood glucose and anthropometric parameters were included. Study selection, data extraction, and quality assessment were performed independently by 2 authors. Results. Twelve studies on a

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Alwadhi, Anshul. "Triphala: A Wonder Drug of Ayurveda." International Journal of Health Sciences and Research 11, no. 7 (2021): 314–16. http://dx.doi.org/10.52403/ijhsr.20210743.

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Triphala is used in the traditional Indian system of medicine. Triphala is composed of three fruits namely Haritaki, Vibhitaki, Amalaki. The fruit of three together called Triphala. It is widely prescribed Ayurvedic drug and is used in various diseases. Triphala is a traditional Ayurvedic formula that tones and supports normal function to the bowel. This three fruit formula is simply a bowel toner, designed to store the muscular function and contractibility of the intestinal wall. It is used as an anti oxidant and possesses various beneficial properties. Key words: Triphala, Ayurveda, Charak S

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Ozah, Biplob. "Triphala: A useful therapeutic supplement during COVID-19 pandemic." Journal of Drug Delivery and Therapeutics 10, no. 4 (2020): 219–20. http://dx.doi.org/10.22270/jddt.v10i4.4153.

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In this communication, efforts have been made to point out two different aspects: the clinical symptoms of COVID-19 and several therapeutic effects of ‘Triphala’. The ‘Triphala’ have been acting as ‘one formula therapy’ since the time of the Ayurveda, and the COVID-19 is not an exception. The relationship between the pre- and post-symptom of COVID-19 and the therapeutic activity of ‘Triphala’ gives us a ray of hope to use Triphala as an anti-corona therapeutic supplement during the pandemic as well as in near future. Keywords: COVID-19, Triphala, Ayurveda, Therapeutic activity

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7

Patel, Hinal, Foram Patel, Vinit Jani, et al. "Anti-pathogenic potential of a classical ayurvedic formulation- Triphala." F1000Research 8 (July 18, 2019): 1126. http://dx.doi.org/10.12688/f1000research.19787.1.

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A classical ayurvedic polyherbal formulation namely Triphala was assessed for its anti-pathogenic potential against five different pathogenic bacteria. Virulence of four of them towards the model host Caenorhabditis elegans was attenuated (by 18-45%) owing to pre-treatment with Triphala (≤20 µg/ml). Triphala could also exert significant therapeutic effect on worms already infected with Chromobacterium violaceum, Serratia marcescens or Staphylococcus aureus. Prophylactic use of Triphala allowed worms to score 14-41% better survival in face of subsequent pathogen challenge. Repeated exposure to

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8

Tsering, Jokyab, and Xianda Hu. "Triphala Suppresses Growth and Migration of Human Gastric Carcinoma Cells In Vitro and in a Zebrafish Xenograft Model." BioMed Research International 2018 (December 10, 2018): 1–6. http://dx.doi.org/10.1155/2018/7046927.

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Objectives. Triphala is an extensively prescribed traditional medicinal formula with potential therapeutic effects on various malignancies such as breast, colon, pancreas, prostate, ovarian, cervical, endometrial, and lymphatic cancer as well as melanoma. This study aimed to investigate Triphala for antitumor activities against gastric cancers. Methods. In vitro tumor growth and migration of human gastric cancer cells were examined using the CCK-8 and Transwell assays, respectively. In vivo tumor progression was studied in a zebrafish xenograft model. The anticancer activity of Triphala was qu

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9

Zhao, Yuhang, Min Wang, Jokyab Tsering, et al. "An Integrated Study on the Antitumor Effect and Mechanism of Triphala Against Gynecological Cancers Based on Network Pharmacological Prediction and In Vitro Experimental Validation." Integrative Cancer Therapies 17, no. 3 (2018): 894–901. http://dx.doi.org/10.1177/1534735418774410.

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Objectives. Triphala is a herbal medicine that has been widely used for treating a variety of ailments. This study aims to systematically analyze the antitumor effects of Triphala on gynecological cancers. Methods. The antineoplastic activities of Triphala on gynecological cancers were analyzed using network pharmacology-based strategies. Afterward, the human ovarian cancer cell line SK-OV-3, cervical cancer cell line HeLa, and endometrial cancer cell line HEC-1-B were selected for experimetal valification. Results. Network pharmacology analysis suggested that Triphala could comprehensively in

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10

Jumpa-Ngern, Piracha, Tullayakorn Plengsuriyakarn, Wiratchanee Mahavorasirikul, and Kesara Na-Bangchang. "Potential Inhibitory and Inducing Effects of Triphala Formulation on Cytochrome P450 Enzymes." Trends in Sciences 19, no. 18 (2022): 5819. http://dx.doi.org/10.48048/tis.2022.5819.

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Triphala formulation is one of the most common traditional medicines used for several health conditions. The study aimed to investigate the inhibitory and inducing potentials of Triphala formulation, including its active compounds gallic acid and ellagic acid, on cytochrome P450 (CYP450) enzymes. The inhibitory effects of Triphala formulation, gallic acid and ellagic acid on the 5 major human CYP450 enzymes were evaluated using a bioluminescent CYP450 inhibition assay. Evaluation of inducing effect of Triphala formulation on CYP1A2 and CYP3A1 mRNA expression following daily oral doses of 1,000

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11

Ghimire, Alizza, Pratima Bhattarai, and Promish Adhikari. "A Review on the Ingredients of Triphala (Harro, Barro and Amala)." Kalika Journal of Multidisciplinary Studies 5, no. 1 (2023): 143–56. http://dx.doi.org/10.3126/kjms.v5i1.60917.

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Triphala is a poly-herbal formula made up of three equal proportions of herbal fruits, Harro, Barro, and Amala, found in tropical and sub-tropical regions of Asia. This study aimed to review the phytochemicals, potential uses, and constituents of Triphala using PRISMA standards. Data was collected from well-known bibliometric information sources. All the obtained information was analysed systematically and represented in a tabular and descriptive form. The result shows that the main chemical constituents of Triphala include Vitamin C, carotene, nicotinic acid, riboflavin, tannins, tannins, ant

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Shanker, Shyam Sundar, Krishna Santosh Kumar, Sharmila Hussain, Annapoorni Hariharan та Tamizhselvi Ramasamy. "TNF-α, An Inflammatory Path, Rerouted Through Alternate Medicinal Channels". Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4514—S4516. https://doi.org/10.4103/jpbs.jpbs_1058_24.

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ABSTRACT Introduction: This study emphasizes the efficacy of triphala as a therapeutic agent over inflammatory condition in hydrogen sulfide (H2 S) mediated inflammatory path in the presence of titanium (Ti) discs. Materials and method: In the presence of triphala extracts, lipopolysaccharidetreated macrophages showed reduction in production of inflammatory mediators and intercellular free radicals (ROS) and downregulation of mRNA in TNF. Results: Thus in the presence of propargylglycine, reduction of TNFα by triphala in the H2 S inhibited group showed that the mechanism of action of triphala

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Ning, Wanchen, Simin Li, Jokyab Tsering, et al. "Protective Effect of Triphala against Oxidative Stress-Induced Neurotoxicity." BioMed Research International 2021 (April 7, 2021): 1–11. http://dx.doi.org/10.1155/2021/6674988.

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Background. Oxidative stress is implicated in the progression of many neurological diseases, which could be induced by various chemicals, such as hydrogen peroxide (H2O2) and acrylamide. Triphala is a well-recognized Ayurvedic medicine that possesses different therapeutic properties (e.g., antihistamine, antioxidant, anticancer, anti-inflammatory, antibacterial, and anticariogenic effects). However, little information is available regarding the neuroprotective effect of Triphala on oxidative stress. Materials and Methods. An in vitro H2O2-induced SH-SY5Y cell model and an in vivo acrylamide-in

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14

Dineshkumar, Thayalan, Nirmala Anandan, Krishnan Rajkumar, and Indumathi Nandhakumar. "Immunomodulatory effects of Triphala and its constituents in oral squamous cell carcinoma and oral precancer." Journal of Oral and Maxillofacial Pathology 28, no. 4 (2024): 657–64. https://doi.org/10.4103/jomfp.jomfp_53_24.

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Abstract Oral squamous cell carcinoma shows increased occurrence in those who consume tobacco products, alcohol, betel quid, and areca nut, and is also considered to occur due to genetic alteration. Though there are numerous advancements in treatment, survival remains a question with late diagnosis. Hence, there are continuous inventions of new drugs. The introduction of Ayurveda in the therapy has paved the way for the longevity of the patients affected. One such introduction is the use of Triphala. The current study aims to review the anti-oxidant, anti-proliferative, anti-microbial, and apo

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Phimarn, Wiraphol, Pawich Paktipat, Chatmanee Taengthonglang, Kritsanee Saramunee, and Bunleu Sungthong. "A meta-analysis and meta-regression study of the effects of Triphala on anthropometric parameters." Journal of Herbmed Pharmacology 11, no. 4 (2022): 475–82. http://dx.doi.org/10.34172/jhp.2022.54.

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Triphala is a medicinal plant that can improve anthropometric parameters. Although Triphala is widely used, especially in India and Thailand, its efficacy is still controversial. Consequently, the purpose of this meta-analysis and meta-regression analysis was to assess the safety of Triphala and its effects on anthropometric parameters. A comprehensive review and meta-analysis of randomized controlled trials assessing the safety of Triphala and its effects on anthropometric parameters were conducted by searching PubMed, ScienceDirect, Web of Science, and ThaiLIS databases. Two authors independ

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Devram Mane, Dr Kartiki, and Dr Akbar Walandkar. "The Role of Triphala Kwatha in the Management of NonHealing Ulcers." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 1849–52. https://doi.org/10.35629/4494-100318491852.

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Non-healing ulcers, commonly corresponding to Dushta Vrana in Ayurvedic literature, remain a significant clinical challenge due to impaired wound healing mechanisms. Triphala, a classical polyherbal Ayurvedic formulation consisting of Haritaki (Terminalia chebula), Bibhitaki (Terminalia bellirica), and Amalaki (Emblica officinalis), has long been valued for its woundcleansing (Shodhana) and healing (Ropana) properties. This review evaluates the pharmacological actions, traditional uses, and clinical potential of Triphala Kwatha (decoction) in the treatment of chronic, non-healing ulcers, based

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ARORA, JYOTI, SIMRAN JIT, NUTAN RANI, DEEPAK KUMAR, SABA ZULFIQAR, and SANDIPANA CHAKRABORTY AND NISHA VASHISHTA. "Antimicrobial Finishing of Textiles by Application of Triphala, an Ayurvedic Medicine." JOURNAL OF ENVIRONMENT AND BIO-SCIENCE 39, no. 01 (2025): 81. https://doi.org/10.59467/jebs.2025.39.81.

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Triphala is frequently employed in herbal formulations due to its antibacterial, antioxidant, anti-inflammatory, and antitumor effects. Compounds of phenols, flavonoids, tannins, alkaloids, terpenoids, and glycosides provide Triphala its antibacterial qualities. In this study, these antimicrobial properties have been explored for textile finishing. Textiles manufactured using natural antimicrobial agents correspond to regulatory standards and are environmentally sustainable, non-toxic, and non-carcinogenic. Current research utilized 25% (w/v) aqueous extract of Triphala for antibacterial treat

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Saini, Neha, Abhinav C. Singhal, Aditi S. Jain, Jayesh Tiwari, and Pratik Surana. "Antibacterial Efficacy of Neem, Triphala, Green Tea, and Combination of Neem with Triphala Extract against Enterococcus faecalis: An in vitro Study." International Journal of Experimental Dental Science 6, no. 2 (2017): 65–67. http://dx.doi.org/10.5005/jp-journals-10029-1158.

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ABSTRACT Introduction The main objective of root canal treatment is to disinfect the entire root canal system, and irrigation is an important step in reducing the bacterial load from the root canal system. However, irrigants currently used in the field of endodontics have their share of limitations, and the search for an ideal root canal irrigant continues. The use of herbal extracts as endodontic irrigants is today gaining popularity. Aims and objectives To evaluate and compare the antimicrobial potential of herbal extracts, such as neem (Azadirachta indica), triphala (Terminalia chebula), gr

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Mahajan, Darshna, and Sapna Jain. "Antimicrobial analysis of Triphala and comparison with its individual constituents." Indian Journal of Pharmaceutical and Biological Research 3, no. 03 (2015): 55–60. http://dx.doi.org/10.30750/ijpbr.3.3.9.

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Triphala, a well known ayurvedic formulation is used against number of ailments since ancient times. It consists of Emblica officinalis, Terminalia chebula and Terminalia bellerica in equal proportion. Triphala as a whole and its three individual constituents show specific antimicrobial activity against certain bacteria and fungi. Antimicrobial activity of aqueous extract of triphala and its constituents was studied against P.aeruginasa, E.coli , B.subtilis, K. pneumoniae and S.aureus by cup-plate method. Triphala was found strongly bactericidal against P. aeruginosa with 1.8 cm of inhibitory

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Sato, Vilasinee Hirunpanich, Bunleu Sungthong, Narawat Nuamnaichati, Prasob-orn Rinthong, Supachoke Mangmool, and Hitoshi Sato. "In Vivo and In Vitro Evidence for the Antihyperuricemic, Anti-inflammatory and Antioxidant Effects of a Traditional Ayurvedic Medicine, Triphala." Natural Product Communications 12, no. 10 (2017): 1934578X1701201. http://dx.doi.org/10.1177/1934578x1701201028.

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The objectives of the present study were to demonstrate the antihyperuricemic effect of triphala, a formulation of traditional Ayurvedic medicine, in potassium oxonate-induced hyperuricemic mice in vivo, and to examine its inhibitor effects on xanthine oxidase (XOD), inflammatory mediators and DPPH radicals in vitro. The water extract of triphala was determined to contain the total phenolics and total flavonoids of 317.6 ± 9.2 mg GAE/g and 7.73 ± 0.26 mg QE/g, respectively. Oral administrations of triphala significantly reduced the plasma uric acid levels of potassium oxonate-induced hyperuric

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Krishna Murthy, Snehal D. Jagadale, Solunke R. S., Shete R. V., and Priyanka Nangare. "Antidiabetic potential of Triphala Guggul - an ayurvedic formulation in alloxan-induced diabetes animal model." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 315–22. http://dx.doi.org/10.26452/ijrps.v11i1.1823.

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The purpose of this study was to evaluate the potential antidiabetic drug Triphala guggul (TG), an indigenous polyherbal Ayurvedic formulation in an alloxan-induced diabetes rat model. Diabetes mellitus was induced in rats. The rats were divided into nine groups, including the groups of normal control which received the vehicle, the standard group (Glibenclamide) and rats with induced diabetes were treated with the tablet of Triphala guggul and Triphala guggul churna in doses of 100, 200, 400 mg/kg body weight, respectively. They were administered orally for 28 days on a single dose. Blood was

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Mayuresh Joshi and Prerna Khanchandani. "A Systematic Review of Triphala Churna: A Focus on Ingredient Synergism and its Implications for Human Health." International Journal of Scientific Research in Science and Technology 11, no. 6 (2024): 791–800. https://doi.org/10.32628/ijsrst24114329.

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Triphala Churna, a revered Ayurvedic formulation, has gained global recognition for its multifaceted health benefits. This review delves into the traditional uses and modern scientific evidence supporting the therapeutic potential of Triphala Churna and its constituent fruits: Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula). Amalaki, rich in vitamin C and antioxidants, exhibits potent anti-inflammatory and immune-boosting properties. Bibhitaki possesses anti-inflammatory, antimicrobial, and hepatoprotective actions. Haritaki demonstrates laxat

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Singh, M. P., S. Vashisht, V. Chawla, and P. Kumari. "WOUND HEALING ACTIVITY OF TRIPHALA IN EXPERIMENTALLY INDUCED DIABETIC RATS." INDIAN DRUGS 54, no. 04 (2017): 70–75. http://dx.doi.org/10.53879/id.54.04.10832.

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Aim of the present study was to explore the wound healing potential of Triphala extract. Triphala ointment (15% w/w) was used in the study for excision wound model. For dead space wound model Triphala extract (200 mg/kg) was administered orally. Extract of Triphala topically applied in excision wound model was found to possess wound healing property. On day 11th, the extract treated animals showed wound contraction to the extent of 87.63% and 94.77%, compared with control group of animals. In dead space wound model, oral administration of the extract was found to increase the wet and dry granu

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Ravindra B., Malabadi, Kolkar Kiran P., Meti Neelambika T., and Chalannavar Raju K. "Triphala: An Indian Ayurvedic herbal formulation for coronavirus (SARS-CoV-2) disease (Covid-19)." International Journal of Current Research in Biosciences and Plant Biology 8, no. 08 (2021): 18–30. http://dx.doi.org/10.20546/ijcrbp.2021.808.003.

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This review paper updated the significance and pharmaceutical effects of Triphala as an alternative traditional herbal Indian folk medicine used as a immunity booster during the recent outbreak of coronavirus-2 (SARS-CoV-2) mutants, Delta (B.1.617.2) and Delta Plus (AY.1). The current outbreak of coronavirus-2 mutants, Delta (B.1.617.2) and Delta Plus (AY.1) is wreaking havoc in India. The new epicentre of the highest number of corona viral mutant infection cases and death rate has been recorded in Indonesia. The hallmark of the coronavirus disease is the cytokine storm, a massive cytokine and

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Desai, Maniti, Meghna Adhvaryu, Rishee K. Kalariya, and Rajkumar B. K. "Molecular Authentication of Polyherbal Formulation - Triphala Churna." Journal of Advances in Biology & Biotechnology 27, no. 11 (2024): 1269–83. http://dx.doi.org/10.9734/jabb/2024/v27i111713.

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Aim: The present study aims to design a molecular authentication protocol for the renowned polyherbal formulation Triphala with the help of recent advances in the DNA barcoding technology. Purpose of Work: In recent decades, ayurvedic polyherbal medications have gained immense popularity worldwide. The quality of some of these herbal products has raised serious concerns regarding their authenticity and safety. The therapeutically potent original herbal species component of the polyherbal formulations are often substituted with cheaper or easily available adulterants or sometimes omitted entire

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Panomsuk, Suwannee, Songsriwittaya Kamolporn, Chanmeesri Natnaree, Boonyatulanont Paroch, and Nuntharatanapong Nopparat. "Development of Triphala Extract-Loaded Mucoadhesive Films for Aphthous Ulcers." Key Engineering Materials 901 (October 8, 2021): 92–97. http://dx.doi.org/10.4028/www.scientific.net/kem.901.92.

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Triphala is a traditional Thai herbal formulation containing dried fruits of Phyllanthus emblica, Terminalia bellirica, and Terminalia chebula. It has wound healing, antioxidant and anti-inflammatory activities. The objective of this research was to formulate mucoadhesive films containing Triphala extract for aphthous ulcers treatment. The films were formulated using hydroxypropyl methylcellulose, HPMC, (5, 8, 10% w/w) as a film-forming polymer and glycerin (5% w/w) as a plasticizer. Triphala extract (2.5, 5, 10% w/w) was incorporated into the film during the film preparation. The films were t

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Raja, B. Kumara, and Kavitha Devi. "Role of Triphala in Oral Health: A Systematic Review and Meta-Analysis." Journal of Indian Association of Public Health Dentistry 21, no. 2 (2023): 108–17. http://dx.doi.org/10.4103/jiaphd.jiaphd_199_21.

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Aim: Critically assessed reviews on the effectiveness of Triphala for the promotion of oral health are hard to come by. As a result, the goal of this study was to conduct a systematic evaluation of the existing literature to determine the impact of Triphala on oral health. Materials and Methods: PubMed, PubMed Central, Campbell systematic review, Cochrane, Embase, Google Scholar, and Scopus were used to perform a systematic review of the literature. This review includes only randomized control trials (RCTs) comparing Triphala to chlorhexidine (CHX) or placebo. To perform risk of bias and meta-

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Suryavanshi, Sachin V., Mayuresh S. Garud, Kalyani Barve, Veeranjaneyulu Addepalli, Sachin V. Utpat та Yogesh A. Kulkarni. "Triphala Ameliorates Nephropathy via Inhibition of TGF-β1 and Oxidative Stress in Diabetic Rats". Pharmacology 105, № 11-12 (2020): 681–91. http://dx.doi.org/10.1159/000508238.

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<b><i>Introduction:</i></b> Advanced glycation end products, oxidative stress, and TGF-β expression play a crucial role in pathophysiology of diabetic nephropathy. Inhibition of oxidative stress and TGF-β expression by natural traditional medicines may give an economic and safe alternative treatment option. Triphala churna, a traditional medicine, has been proved to have potent antioxidant activity, and individual components of it have shown significant antidiabetic activity. Hence, the present study was designed to study the effect of Triphala churna in diabetic nephro

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Biradar, Yogesh S., Sheetal Jagatap, K. R. Khandelwal, and Smita S. Singhania. "Exploring of Antimicrobial Activity of TriphalaMashi—AnAyurvedicFormulation." Evidence-Based Complementary and Alternative Medicine 5, no. 1 (2008): 107–13. http://dx.doi.org/10.1093/ecam/nem002.

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TriphalaMashiis an ayurvedic formulation that was prepared in our lab. Aqueous and alcoholic extracts of both Triphala and TriphalaMashiwere used, to evaluate antimicrobial activity. Comparative phytochemical profile of Triphala and TriphalaMashiwas done by preliminary phytochemical screening, total phenolic content and thin layer chromatography (TLC). Antimicrobial activity includes isolation of pathogens from clinical samples, its characterization, testing its multiple drug resistance against standard antibiotics and antimicrobial activity of aqueous and alcoholic extracts of both Triphala a

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Revathi, Sundaramoorthy, V. Gopal, and G. Jeyabalan. "ACUTE TOXICITY AND IN-VIVO LAXATIVE STUDIES OF THE TRIPHALA EXTRACT IN EXPERIMENTAL ANIMALS." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 341–47. http://dx.doi.org/10.22270/jddt.v9i4.3170.

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Triphala has been extensively used in traditional medicine for laxative, antidiabetic, expectorant, astringent, anti-aging etc. The acute toxicity of methanolic extracts of Triphala in 300 mg, 600 mg, and 1000 mg/kg has not yet been studied. The current studies were done by employing Swiss Albino mice as experimental animal. The methanolic extracts of Triphala were considered safe up to a dose of 1000 mg/kg when evaluated for acute oral toxicity in accordance with the OECD (Organization for Economic Cooperation and Development) guidelines. The results of acute toxicity showed no signs of toxic

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Kumar, Sandhya, and Satish Pai. "Characterisation of Phenolics to comprehend ‘Gunantaradhana (Qualitative transformation)’ of Madhu (Honey) with special reference to Gallic and Tannic acid components." JOURNAL OF RESEARCH IN TRADITIONAL MEDICINE 9, no. 2 (2023): 44. http://dx.doi.org/10.5455/jrtm.2023/172145.

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Background: Madhu (honey) has been used as a remedy for diseases such as Prameha (diabetes). Medoroga (dyslipidaemia) and Sthoulya (obesity) are rooted in the principle of "Yogavahitva” or synergism. Kaiyadeva Nighantu speculates on honey's potential after Samskara or processing to obtain specific outcomes. Differences in activities of Madhu mixed and processed with Triphala Kashaya are attributed to polyphenols, among which, Tannic and Gallic acids are significant. Objective: The present study is aimed at identifying Phenolic components in Madhu in the form of Samyoga and Samskara with Tripha

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Intatham, Supaporn, Weerakit Taychaworaditsakul, Parirat Khonsung, et al. "Safety Evaluation for Acute and Chronic Oral Toxicity of Maha Pigut Triphala Contains Three Medicinal Fruits in Sprague-Dawley Rats." Biology 13, no. 12 (2024): 1005. https://doi.org/10.3390/biology13121005.

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Maha Pigut Triphala is the herbal mixture of three fruits consisting of T. bellirica, T. chebula, and E. officinalis also known as P. emblica. Humans regularly eat the fresh fruits of these plants on a daily basis. Maha Pigut Triphala is one of the widely known herbal medicinal formulas used in traditional Thai medicine. Besides studying pharmacological properties, attention should also be paid to the safety and toxicity studies of herbal medicines. The objective of the present study was to evaluate the acute and chronic oral toxicity of Maha Pigut Triphala (2:1:3) in Sprague-Dawley rats. A si

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Sundaramoorthy, Revathi, V. Gopal, and G. Jeyabalan. "Formulation and Evaluation of Floating Tablets of Sitagliptin with Extract of Triphala." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 38–47. http://dx.doi.org/10.22270/jddt.v9i4-a.3278.

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The aim of the present work is to formulate, optimize and evaluate hydrodynamically balanced antidiabetic system incorporated with sitagliptin and phytochemical constituents of Triphala extract for the treatment of constipation associated with diabetes. The Triphala churna of two different ratios, 1:1:1 (TC1) and 1:2:4 (TC2) were subjected to hot percolation using Soxhlet apparatus using methanol as solvent. The floating matrix tablets of Sitagliptin with methanolic Triphala extract was prepared by wet granulation technique using HPMC K4M as polymer, starch/honey as binder and sodium bicarbona

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Rawat, Neelam, Yadevendra Yadav, Shuchi Mitra, Usha Sharma, and Khem Chand Sharma. "ANTI-INFLAMMATORY AND ANTI-MICROBIAL ACTION OF TRIPHALA GUGGULU: A REVIEW." International Journal of Research in Ayurveda and Pharmacy 13, no. 04 (2022): 121–30. http://dx.doi.org/10.7897/2277-4343.1304101.

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Triphala Guggulu, an Ayurvedic herbal formulation, consists of dried powder of fruits of three plants commonly known as Triphala: Emblica officinalis Gaertn. (Euphorbiaceae), Terminalia bellerica Roxb. (Combretaceae) and Terminalia chebula Retz. (Combretaceae) along with Piper longum Linn. (Piperaceae), combined with the oleo-gum resin of Commiphora wightii Arnott. Bhandari (Burseraceae). It is mentioned in the Ayurvedic Formulary of India (AFI) taken from Sharngadhar Samhita for several therapeutic uses. This formulation is indicated in the treatment of Bhagandara (fissure-in-ano), Gulma (Ben

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Dhivya, L. S., M. Haritha, G. V. Anjana, and D. Priya. "<i>In Silico</i> Screening of Triphala Churna against Bacterial Agents." Journal of Natural Remedies 22, no. 2 (2022): 221. http://dx.doi.org/10.18311/jnr/2022/28664.

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Triphala Churna consisting Triphala and its constituents have been revealed to have antibacterial properties against human pathogens. The phenolic ring of phytochemicals has been confirmed to be toxic against microorganisms and hence responsible for antibacterial effect. It has also been found to possess antimicrobial, anti-inflammatory, anti-oxidant, and other properties. The objective of this project is to investigate which bioactive compounds of Triphala churna have antibacterial action and can protect humans from infection. The majority of the molecules in phytochemical examination were po

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N. Mahajan, K., A. K. Singhai, and G. P. Vadnere. "Investigation on Anticataract Activity of Triphala Ghrita." E-Journal of Chemistry 8, no. 3 (2011): 1438–43. http://dx.doi.org/10.1155/2011/571627.

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Lab prepared Triphala ghrita was studied for its possible anticataract activity on galactose induced cataract in Swiss albino rats. Administration of Triphala ghrita at a dose of 216 mg/200 g, 1080 mg/200 g and 2160 mg/200 g of rat orally offered significant dose dependent protection against galactose induced cataract and delayed the onset and progression of cataract. It was seen that the dose of 1080 mg of Triphala ghrita did not show stage II cataract in 14 days and stage III in 21 days. It did not show even stage III and stage IV cataract after 30 days whereas group B and group C showed sta

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Kalva, Sireesha, Neha Andhi, Ramya Sree Yenni, P. Sai Ganesh, A. Madhu, and M. Nihal. "Investigation of Anti Inflammatory Activity of Triphala Hydrogels in Carrageenan Induced Paw Edema Model." Asian Journal of Pharmaceutical Research and Development 11, no. 5 (2023): 12–20. http://dx.doi.org/10.22270/ajprd.v11i5.1315.

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Inflammation is a reaction of a living vascularized tissue to an injury, conventional or synthetic drugs used in the treatment of inflammatory diseases are inadequate, it sometimes has serious stroke effects. So, number of herbal medicines are recommended for the treatment of inflammation that has no side effects. Hence our study focused to investigate bioactive compounds for anti-inflammatory activity. Folk medicine and ethnopharmacological data can provide a broad range of plants with promising anti-inflammatory activity. Triphala, an ayurvedic formula composed of three different plants. Ter

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Shanker, Shyam Sundar, Tiasha Dasgupta, Sharmila Hussain, H. Annapoorni, and Ramasamy Tamizhselvi. "Protective Effect of Triphala Mediated by H2S Signaling Pathway in LPS-Induced RAW Macrophages." Journal of Pharmacy and Bioallied Sciences 16, Suppl 5 (2024): S4511—S4513. https://doi.org/10.4103/jpbs.jpbs_1059_24.

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ABSTRACT Introduction: MacrophagesHydrogen sulfide (H2 S), an endogenously produced gasotransmitter, is a wellknown inflammatory agent production successfully controlled with triphala in macrophages. Materials and method: The ELISA analysis revealed that triphala extracts suppress the protein expression of NFκB (p65) and downregulation of the CSE gene expression. Moreover, in the presence of propargylglycine (PAG) the expression of NFκB and CSE gene was further reduced. Results: These results suggest that triphala could be a potent antiinflammatory effect that could be used for the treatment o

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Pamnani, Vikas S., and Sunita D. Ram. "SUGANDHI TRIPHALA: AN OVERVIEW." International Ayurvedic Medical Journal p8, no. 02 (2024): 131–33. http://dx.doi.org/10.46607/iamj04p8022024.

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The term Triphala is famous in Ayurveda literature. The word Triphala is commonly used for Haritaki, Vibhitaki, and Amalaki. But Sugandhi Triphala has three powerful ingredients, Jatiphala, Puga, and Lavanga, and they have been used for centuries in various cultures for their numerous health benefits and culinary uses. These ingredients, also known as nutmeg, Betel nut, and cloves, respectively, are rich in flavor and possess medicinal properties that make them highly sought after. It is astringent, Madhura in Vipaka, and valuable in Vibandha. It acts on Vata kapha dosha.

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Garasia, Jaynika S., Mandip Goyal, Harisha C. R., and Vinay J. Shukla. "Pharmacognostical and pharmaceutical analysis of Triphala Kajjali tablet-an ayurvedic herbomineral formulation for metabolic syndrome." International Journal of Advances in Medicine 8, no. 2 (2021): 195. http://dx.doi.org/10.18203/2349-3933.ijam20210263.

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Background: Triphala is one of the most easily available and commonly used medicine which contains fine powder of three fruits viz. Terminalia chebula Retz. (Haritaki), Terminalia bellerica Roxb. (Bibhitaki) and Embilica officinalis Gaertn. (Amalaki) and is indicated as one of the drugs for management of disorders of Kapha and Meda. Due to bitter and astringent taste of Triphala in the powder form is a major complaint of the patients. So, to discover that form of Triphala, which is easy to take, effective in low dose, has long shelf life and simple to dispense is the need. For assurance of qua

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Chandran, Keerthana, Dinesh Sridhar, Bindu Meera John, Srilekha Jayakumar, Karthikeyan Arumugam, and Prashanth Ponnusamy. "Comparison of antimicrobial efficacy of green tea extract and Triphala as root canal irrigants against Fusobacterium nucleatum using real-time polymerase chain reaction – An in vitro study." Endodontology 36, no. 1 (2024): 44–48. http://dx.doi.org/10.4103/endo.endo_80_23.

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Aim: Fusobacterium nucleatum has gained attention in the endodontic literature as it is a predominant microorganism in primary, secondary, and persistent root canal infections. Current irrigants have lot of drawbacks and are unlikely to predictably achieve a bacteria-free root canal system, which can lead to these failures. Herbal alternatives are now gaining popularity in the field of endodontics, paving a new way in the disinfection of root canals. The aim of this study is to evaluate the antimicrobial efficacy of green tea extract and Triphala as root canal irrigants against F. nucleatum us

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Phetkate, Pratya, Tanawan Kummalue, Yaowalak U-pratya, and Somboon Kietinun. "Significant Increase in Cytotoxic T Lymphocytes and Natural Killer Cells by Triphala: A Clinical Phase I Study." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/239856.

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Background. Searching for drugs or herbal formulations to improve the immunity of HIV/AIDS positive people is an important issue for researchers in this field. Triphala, a Thai herbal formulation, is reported to have immunomodulatory effects in mice. However, it has not yet been investigated for immunostimulatory and side effects in healthy human volunteers.Objective. To evaluate the immunostimulatory and side effects of Triphala in a clinical phase I study.Materials and Methods. All volunteers took Triphala, 3 capsules per day for 2 weeks. Complete physical examination, routine laboratory ana

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Pamnani, Vikas S., and Sunita D. Ram. "Triphala and Its Types: An Analytical Overview." International Research Journal of Ayurveda & Yoga 06, no. 12 (2023): 85–88. http://dx.doi.org/10.47223/irjay.2023.61215.

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Triphala is a traditional Ayurvedic herbal formulation that has been used for centuries in India. It is composed of three fruits: Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), and Haritaki (Terminalia chebula). Triphala is renowned for its numerous health benefits and is considered a cornerstone of Ayurvedic medicine. It is considered as good as rasayana, for cosmetics purpose to improve skin and hair quality, and for diabetic wound management. It is used as a general health promoter which facilitates nourishment to all dhatu. This paper aims to provide an analytical overvie

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Wiwanitkit, Viroj. "Anticataract potential of Triphala." Journal of Ayurveda and Integrative Medicine 2, no. 2 (2011): 51. http://dx.doi.org/10.4103/0975-9476.82513.

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Deka, Purabi, and Arun Kumar. "PHARMACOLOGICAL EVALUATION OF TRIPHALA CHURNA INSTREPTOZOTOCIN (I. C. V.) INDUCED DEMENTIA IN RATS." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 3 (2018): 97. http://dx.doi.org/10.22159/ijpps.2018v10i3.22795.

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Objective: The objective of the study was to investigate the memory improving activity of Triphala Churna hydro-methanolic fruit extract on learning and memory functions in Streptozotocin (I. C. V) induced dementia in rats by using morris water maze and elevated plus maze.Methods: A total of 42 albino wistar rats weighing 80-100 g were randomized into 7 equal groups as follows: Normal control group received normal saline (1 ml/kg p. o.) for 24 d, STZ treated group (3 mg/kg, i. c. v) were administered in two dosage regimen i.e. on first day and third day.), Standard group: Streptozotocin (3 mg/

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Singh, Arjun, Himanshu Sharma, Bhavana Srivastava, and Ravindra Singh. "Markers Assessment in Triphala (Batch-I, II & III) and its Ingredients from Different Geographical Locations of India through TPC, TFC, HPLC & HPTLC." Current Traditional Medicine 6, no. 2 (2020): 106–20. http://dx.doi.org/10.2174/2215083805666190725125251.

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Background: Relations among markers, quality assessment and standardization of classical preparations like Triphala an Ayurvedic potent formulation are necessary for the selectivity as well as acceptability of genuine plant drugs and formulation. Objective: Qualitative and quantitative evaluations of three batches of in-house Triphala along with its ingredients collected from three different locations of India with respect to assess the six active markers. Method: Phytochemical studies, spectrophotometric estimations (TPC & TFC), chromatographic (HPLC & HPTLC) methods were developed fo

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Sonu, Jacob, Raju Minu, S. Soniya, and Jose Jomol. "Chemical Profiling and In-Vitro Anti-inflammatory Activity of Formulated Herbal Drugs." Journal of Advances in Pharmaceutical Sciences 3, no. 1 (2025): 17–26. https://doi.org/10.5281/zenodo.15062655.

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<em>Chemical profiling is a technique used to analyzing and identifying the chemical components in a sample. This suggests that the drying pre-treatment process enhanced the retention and diversity of bioactive compounds in the herbal compress, potentially leading to improved therapeutic efficacy [1]. Chemical profiling of medicinal plants involves extracting and testing chemicals from the herbal drug to determine their biological activity It careful as a challenging analytical task because of the chemical complexity of these extracts. Chemical profiling of medicinal plants involves extracting

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Yadav, Vishnu. "Development of Quality Control Parameters for Herbal Churna." International journal of therapeutic innovation 2, no. 2 (2024): 111–13. http://dx.doi.org/10.55522/ijti.v2i2.0025.

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To evaluate the quality of medications by measuring the quantity of their active ingredients, standardization of herbal formulation is crucial. The standardization of triphala powder Amalaki (Emblica officinalis), Haritaki (Terminalia chebula), and Bibhitaki (Terminalia belerica) is the subject of this paper. Four commercially available samples of triphala powder were obtained for this study and standardized based on the organoleptic characteristics, physical attributes, physico-chemical properties, preliminary phytochemical analysis, and thin-layer chromatography (TLC) methods as per the guid

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Karthick Raja Namasivayam, S., K. G. P. Avinash, K. Samrat, et al. "Antinociceptive activity of marine derived chitosan coated triphala extract against formalin-induced zebrafish pain model." Journal of Environmental Biology 44, no. 1 (2023): 64–72. http://dx.doi.org/10.22438/jeb/44/1/mrn-5026.

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Aim: The present study aimed to evaluate the antinociceptive effect of Triphala extract coated with marine derived chitosan against the formalin-induced adult zebrafish (Danio rerio) model. Methodology: Marine derived chitosan was extracted from Aspergillus niger and the extracted chitosan was coated witha commercial formulation of Triphala by a simple dispersion method. The prepared formulation was administrated to formalin-induced zebra fish model followed by studying changes in various behavioural parameters like swimming pattern, dark-light cycle pattern, antioxidants which include catalas

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More, Tejaswini M., Anil Deshmukh, Rohan Bargal, and Rekha Jori. "Comparative Clinical study of Triphala Ghrita Aschyotan and Alcaftadine (0.25%) eye drop in the management of Vataj Abhishyanada w.s.r. to Simple Allergic Conjunctivitis." International Journal of Ayurvedic Medicine 13, no. 4 (2023): 910–14. http://dx.doi.org/10.47552/ijam.v13i4.3026.

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Sushrutacharya has described the 76 types of eye diseases in his classical text ‘Sushrut Samhita’. One Chapter of eye diseases known as Sarvagata Roga which includes ‘Netraabhishyanda’. Vataja Abhishyanda is characterized by Nistodan (Pricking pain), Sangharsha (foreign body sensation), Shishirashruta (watery discharge), Alpa Shopha (mild chemosis), Vishushka Bhava (feeling of dryness), Parushya (dryness), and so on, which are very similar to most of the signs and symptoms of Simple Allergic Conjunctivitis. Based on the similarities of signs and symptoms, Vataja Abhishyanda can be co-related w

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