Journal articles: 'Triple-store'

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Leida, Marcello, and Andrej Chu. "Zeus: a distributed triple store for proactive SPARQL queries." International Journal of Business Process Integration and Management 7, no. 1 (2014): 34. http://dx.doi.org/10.1504/ijbpim.2014.060601.

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Morsey, Mohamed, Jens Lehmann, Sören Auer, and Axel-Cyrille Ngonga Ngomo. "Usage-Centric Benchmarking of RDF Triple Stores." Proceedings of the AAAI Conference on Artificial Intelligence 26, no. 1 (2021): 2134–40. http://dx.doi.org/10.1609/aaai.v26i1.8448.

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A central component in many applications is the underlying data management layer. In Data-Web applications, the central component of this layer is the triple store. It is thus evident that finding the most adequate store for the application to develop is of crucial importance for individual projects as well as for data integration on the Data Web in general. In this paper, we propose a generic benchmark creation procedure for SPARQL, which we apply to the DBpedia knowledge base. In contrast to previous approaches, our benchmark is based on queries that were actually issued by humans and applications against existing RDF data not resembling a relational schema. In addition, our approach does not only take the query string but also the features of the queries into consideration during the benchmark generation process. Our generic procedure for benchmark creation is based on query-log mining, SPARQL feature analysis and clustering. After presenting the method underlying our benchmark generation algorithm, we use the generated benchmark to compare the popular triple store implementations Virtuoso, Sesame, Jena-TDB, and BigOWLIM.

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Abburu, Sunitha, and Suresh Babu Golla. "Effective Partitioning and Multiple RDF Indexing for Database Triple Store." Engineering Journal 19, no. 5 (2015): 139–54. http://dx.doi.org/10.4186/ej.2015.19.5.139.

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Mariani, J. A. "Oggetto: An Object Oriented Database Layered on a Triple Store." Computer Journal 35, no. 2 (1992): 108–18. http://dx.doi.org/10.1093/comjnl/35.2.108.

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Cui, Hong, Kenneth Yang Jiang, and Partha Pratim Sanyal. "From text to RDF triple store: An application for biodiversity literature." Proceedings of the American Society for Information Science and Technology 47, no. 1 (2010): 1–2. http://dx.doi.org/10.1002/meet.14504701415.

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Amare, Samson Yohannes, Getu Tadele Taye, Tesfit Gebremeskel Gebreslassie, Ruduan Plug, and Mirjam van Reisen. "Realizing health data interoperability in low connectivity settings: The case of VODAN-Africa." FAIR Connect 1, no. 1 (2023): 55–61. http://dx.doi.org/10.3233/fc-221510.

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VODAN Africa has produced FAIR data in low resource settings. Federated machine actionable data is available in a triple store for visiting. Interoperability facets (I1–I3) were followed to achieve semantic interoperability. Vertical interoperability was also realized with DHIS2.

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Alocci, Davide, Julien Mariethoz, Oliver Horlacher, Jerven T. Bolleman, Matthew P. Campbell, and Frederique Lisacek. "Property Graph vs RDF Triple Store: A Comparison on Glycan Substructure Search." PLOS ONE 10, no. 12 (2015): e0144578. http://dx.doi.org/10.1371/journal.pone.0144578.

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Dau, Frithjof. "Towards Scalingless Generation of Formal Contexts from an Ontology in a Triple Store." International Journal of Conceptual Structures and Smart Applications 1, no. 1 (2013): 18–38. http://dx.doi.org/10.4018/ijcssa.2013010102.

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The EU-funded research project CUBIST investigates how Formal Concept Analysis can be applied as a Visual Analytics tool on top of information stored in a Triple Store (TS). This paper provides first steps for utilizing SPARQL in order to generate formal contexts out of the data in the TS, where the emphasis is put on using object-properties between individuals. Thus it complements FcaBedrock, which will be used in CUBIST as well and focuses on the scaling of datatype-properties between individuals and literals. It is discussed how the approaches of this paper and FcaBedrock can be combined.

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Saldías, María Paz, Pablo Cruz, Ian Silva, et al. "The Cytoplasmic Region of SARAF Reduces Triple-Negative Breast Cancer Metastasis through the Regulation of Store-Operated Calcium Entry." International Journal of Molecular Sciences 24, no. 6 (2023): 5306. http://dx.doi.org/10.3390/ijms24065306.

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Triple-negative breast cancer has a poor prognosis and is non-responsive to first-line therapies; hence, new therapeutic strategies are needed. Enhanced store-operated Ca2+ entry (SOCE) has been widely described as a contributing factor to tumorigenic behavior in several tumor types, particularly in breast cancer cells. SOCE-associated regulatory factor (SARAF) acts as an inhibitor of the SOCE response and, therefore, can be a potential antitumor factor. Herein, we generated a C-terminal SARAF fragment to evaluate the effect of overexpression of this peptide on the malignancy of triple-negative breast cancer cell lines. Using both in vitro and in vivo approaches, we showed that overexpression of the C-terminal SARAF fragment reduced proliferation, cell migration, and the invasion of murine and human breast cancer cells by decreasing the SOCE response. Our data suggest that regulating the activity of the SOCE response via SARAF activity might constitute the basis for further alternative therapeutic strategies for triple-negative breast cancer.

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Hitz-Gamper, Benedikt Simon, Oliver Neumann, and Matthias Stürmer. "Balancing control, usability and visibility of linked open government data to create public value." International Journal of Public Sector Management 32, no. 5 (2019): 451–66. http://dx.doi.org/10.1108/ijpsm-02-2018-0062.

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Purpose Linked data is a technical standard to structure complex information and relate independent sets of data. Recently, governments have started to use this technology for bridging separated data “(silos)” by launching linked open government data (LOGD) portals. The purpose of this paper is to explore the role of LOGD as a smart technology and strategy to create public value. This is achieved by enhancing the usability and visibility of open data provided by public organizations. Design/methodology/approach In this study, three different LOGD governance modes are deduced: public agencies could release linked data via a dedicated triple store, via a shared triple store or via an open knowledge base. Each of these modes has different effects on usability and visibility of open data. Selected case studies illustrate the actual use of these three governance modes. Findings According to this study, LOGD governance modes present a trade-off between retaining control over governmental data and potentially gaining public value by the increased use of open data by citizens. Originality/value This study provides recommendations for public sector organizations for the development of their data publishing strategy to balance control, usability and visibility considering also the growing popularity of open knowledge bases such as Wikidata.

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MARX, EDGARD, TOMMASO SORU, SAEEDEH SHEKARPOUR, SÖREN AUER, AXEL-CYRILLE NGONGA NGOMO, and KARIN BREITMAN. "TOWARDS AN EFFICIENT RDF DATASET SLICING." International Journal of Semantic Computing 07, no. 04 (2013): 455–77. http://dx.doi.org/10.1142/s1793351x13400151.

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Over the last years, a considerable amount of structured data has been published on the Web as Linked Open Data (LOD). Despite recent advances, consuming and using Linked Open Data within an organization is still a substantial challenge. Many of the LOD datasets are quite large and despite progress in Resource Description Framework (RDF) data management their loading and querying within a triple store is extremely time-consuming and resource-demanding. To overcome this consumption obstacle, we propose a process inspired by the classical Extract-Transform-Load (ETL) paradigm. In this article, we focus particularly on the selection and extraction steps of this process. We devise a fragment of SPARQL Protocol and RDF Query Language (SPARQL) dubbed SliceSPARQL, which enables the selection of well-defined slices of datasets fulfilling typical information needs. SliceSPARQL supports graph patterns for which each connected subgraph pattern involves a maximum of one variable or Internationalized resource identifier (IRI) in its join conditions. This restriction guarantees the efficient processing of the query against a sequential dataset dump stream. Furthermore, we evaluate our slicing approach on three different optimization strategies. Results show that dataset slices can be generated an order of magnitude faster than by using the conventional approach of loading the whole dataset into a triple store.

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Wei, Shuxian, Siyuan Liu, Shoufu Cao, et al. "Theoretical Investigation of the Fusion Process of Mono-Cages to Tri-Cages with CH4/C2H6 Guest Molecules in sI Hydrates." Molecules 26, no. 23 (2021): 7071. http://dx.doi.org/10.3390/molecules26237071.

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Owing to a stable and porous cage structure, natural gas hydrates can store abundant methane and serve as a potentially natural gas resource. However, the microscopic mechanism of how hydrate crystalline grows has not been fully explored, especially for the structure containing different guest molecules. Hence, we adopt density functional theory (DFT) to investigate the fusion process of structure I hydrates with CH4/C2H6 guest molecules from mono-cages to triple-cages. We find that the volume of guest molecules affects the stabilities of large (51262, L) and small (512, s) cages, which are prone to capture C2H6 and CH4, respectively. Mixed double cages (small cage and large cage) with the mixed guest molecules have the highest stability and fusion energy. The triangular triple cages exhibit superior stability because of the three shared faces, and the triangular mixed triple cages (large-small-large) structure with the mixed guest molecules shows the highest stability and fusion energy in the triple-cage fusion process. These results can provide theoretical insights into the growth mechanism of hydrates with other mono/mixed guest molecules for further development and application of these substances.

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González-Montaña, Luis. "Semantic-based methods for morphological descriptions: An applied example for Neotropical species of genus Lepidocyrtus Bourlet, 1839 (Collembola: Entomobryidae)." Biosystematics and Ecology 1 (November 11, 2021): e71620. https://doi.org/10.1553/biosystecol.1.e71620.

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The production of semantic annotations has gained renewed attention due to the development of anatomical ontologies and the documentation of morphological data. Two methods are proposed in this production, differing in their methodological and philosophical approaches: class-based method and instance-based method. The first, the semantic annotations are established as class expressions, while in the second, the annotations incorporate individuals. An empirical evaluation of the above methods was applied in the morphological description of Neotropical species of the genus Lepidocyrtus (Collembola: Entomobryidae: Lepidocyrtinae). The semantic annotations are expressed as RDF triple, which is a language most flexible than the Entity-Quality syntax used commonly in the description of phenotypes. The morphological descriptions were built in Protégé 5.4.0 and stored in an RDF store created with Fuseki Jena. The semantic annotations based on RDF triple increase the interoperability and integration of data from diverse sources, e.g., museum data. However, computational challenges are present, which are related with the development of semi-automatic methods for the generation of RDF triple, interchanging between texts and RDF triple, and the access by non-expert users.

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Baek and Kim. "Optimum Design and Energy Performance of Hybrid Triple Glazing System with Vacuum and Carbon Dioxide Filled Gap." Sustainability 11, no. 19 (2019): 5543. http://dx.doi.org/10.3390/su11195543.

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This study develops a hybrid triple glazing technology that combines vacuum and carbon dioxide (CO2) gaps to help store CO2 in buildings. We determine the optimal thickness of glazing and calculate its thermal transmission (U-value). The amount of energy saved by using the proposed glazing system is then compared with that when using conventional insulating gases (air, argon, and krypton). Therm & Window, a modeling and analysis program for glazing, and EnergyPlus, a building environment and energy evaluation program, were used for the analysis. The optimal thickness determined for the vacuum and CO2 sections is 6.2 mm and 19 mm, respectively. The latter section comprises a 15-mm CO2 gap and 4 mm of glass. The total thickness of the glazing is 25.2 mm and the U-value is 0.259 W/m2∙K. The energy performance of the triple glazing using vacuum and CO2 gaps is between that of glazing using vacuum and air and that using vacuum and krypton gas gaps. Further, its performance is comparable to that of triple glazing using vacuum and argon gas gaps. Therefore, the hybrid triple glazing proposed in this paper represents an advanced glazing technique that can absorb CO2 and reduce energy consumption in buildings.

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Istiqomah, Chairunnisa, Heny Hendrayati, and Mokh Adib Sultan. "Analysis of Business Development In Laptopin.Id Store Through The Triple Layered Business Model Canvas Approach." Business Innovation and Entrepreneurship Journal 5, no. 2 (2023): 124–35. https://doi.org/10.35899/biej.v5i2.657.

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Digitalization forces people to be able to utilize technology in their daily activities. Laptops are a supporting tool for doing work to learning. The used laptop business is booming with prices that are much cheaper than new laptops. With intense competition, a business model is needed so that the business can continue to survive and develop. The purpose of this research is to project the Laptop in business model which will produce the best strategy for decision-making considerations in the context of developing an ongoing business using the Triple Layered Business Model Canvas. The method used in this research is a descriptive method with a case study approach. The steps taken are (1) SWOT Analysis Formulation, (2) Triple Layered Business Model Canvas Strategy Formulation, and (3) PMIA Method. Where this research finds that businesses are in a growth and build position through an integrative strategy by working on the B2B market, in mapping the business model 3 aspects can help Laptop in to create business value, namely (1) economic aspects, by creating consumer forums to create loyal consumers (2) environmental aspects, processing electronic waste through third parties and (3) social aspects, providing opportunities for persons with disabilities to become part of the shop employees. Decision-making on the TLBMC Laptop in elements using the PMIA (Plus Minus Implication Analysis) method gives a total PMIA score sequentially from largest to smallest, namely the economic layer +39, the environmental layer +33, and the social layer +29. These results indicate that the current decision-making in Laptop in business development is appropriate and feasible to continue.

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Bu, Kai, Hai Jun Liu, Hui Xu, and Zhao Lin Sun. "Large Capacity Cache Design Based on Emerging Non-Volatile Memory." Applied Mechanics and Materials 513-517 (February 2014): 918–21. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.918.

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A triple-level-cell (TLC) STT-RAM architecture was proposed basing on parallel MLC MTJ and serial MLC MTJ. A TLC STT-RAM cell can store three bit which will offer higher capacity density compared with SLC STT-RAM. The write process is also analyzed that it contains three types of basic states transitions. Through mapping soft, medium and hard domains to three individual cache lines, the access to soft lines can perform as accessing SLC STT-RAM-based cache. The amount of three-step operations is also much reduced. .

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Nys, G. A., J. P. Kasprzyk, P. Hallot, and R. Billen. "TOWARDS AN ONTOLOGY FOR THE STRUCTURING OF REMOTE SENSING OPERATIONS SHARED BY DIFFERENT PROCESSING CHAINS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4 (September 19, 2018): 483–90. http://dx.doi.org/10.5194/isprs-archives-xlii-4-483-2018.

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Abstract. This paper proposes an ontology to structure and describe processing chains in the remote sensing field. These chains are made up of elementary elements (operations) organized in collections. The collection notion, including information about order and repeatability of the elements, is widely defined by using the relations between their constituting items and relations to the whole data store. Applications of the ontology are illustrated with web services provided by a platform for users and providers of processing chains. A graphical interface facilitates data integration in a RDF triple store. Thanks to the management of metadata (ISO19115-3), relevant information can be requested by intelligent search engines. Graph analysis, errors management and consistency rules are computed in order to gather coherent information from the different sources. Results of these analyses are then used by machine learning algorithms for new knowledge discovery.

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Lee Moon-Ho and Choi Sung Pil. "Research on Minimizing Access to RDF Triple Store for Efficiency in Constructing Massive Bibliographic Linked Data." Journal of Korean Library and Information Science Society 48, no. 3 (2017): 233–57. http://dx.doi.org/10.16981/kliss.48.3.201709.233.

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Ratnam, Joseline, Barbara Zdrazil, Daniela Digles, et al. "The Application of the Open Pharmacological Concepts Triple Store (Open PHACTS) to Support Drug Discovery Research." PLoS ONE 9, no. 12 (2014): e115460. http://dx.doi.org/10.1371/journal.pone.0115460.

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Karampiperis, Pythagoras, Nikos Manouselis, and Stasinos Konstantopoulos. "Using a POWDER Triple Store for Boosting the Real-time Performance of Global Agricultural Data Infrastructures." Procedia Computer Science 9 (2012): 1578–87. http://dx.doi.org/10.1016/j.procs.2012.04.173.

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Garrido-Morgado, Álvaro, and Óscar González-Benito. "Applying the triple coherence line to in-store marketing plans to increase private label market share." Journal of Retailing and Consumer Services 77 (March 2024): 103642. http://dx.doi.org/10.1016/j.jretconser.2023.103642.

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Tao, Chen, Rongrong Shan, Hui Li, Dongsheng Wang, and Wei Liu. "An Agglomerative-adapted Partition Approach for Large-scale Graphs." International Journal of Librarianship 4, no. 1 (2019): 3. http://dx.doi.org/10.23974/ijol.2019.vol4.1.106.

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In recent years, an increasing number of knowledge bases have been built using linked data, thus datasets have grown substantially. It is neither reasonable to store a large amount of triple data in a single graph, nor appropriate to store RDF in named graphs by class URIs, because many joins can cause performance problems between graphs. This paper presents an agglomerative-adapted approach for large-scale graphs, which is also a bottom-up merging process. The proposed algorithm can partition triples data in three levels: blank nodes, associated nodes, and inference nodes. Regarding blank nodes and classes/nodes involved in reasoning rules, it is better to store with an optimal neighbor node in the same partition instead of splitting into separate partitions. The process of merging associated nodes needs to start with the node in the smallest cost and then repeat it until the final number of partitions is met. Finally, the feasibility and rationality of the merging algorithm are analyzed in detail through bibliographic cases. In summary, the partitioning methods proposed in this paper can be applied in distributed storage, data retrieval, data export, and semantic reasoning of large-scale triples graphs. In the future, we will research the automation setting of the number of partitions with machine learning algorithms.

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Yue, Lili, Liuqing Wang, Yangchun Du, et al. "Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells." Cells 9, no. 2 (2020): 275. http://dx.doi.org/10.3390/cells9020275.

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Being the largest the Ca2+ store in mammalian cells, endoplasmic reticulum (ER)-mediated Ca2+ signalling often involves both Ca2+ release via inositol 1, 4, 5-trisphosphate receptors (IP3R) and store operated Ca2+ entries (SOCE) through Ca2+ release activated Ca2+ (CRAC) channels on plasma membrane (PM). IP3Rs are functionally coupled with CRAC channels and other Ca2+ handling proteins. However, it still remains less well defined as to whether IP3Rs could regulate ER-mediated Ca2+ signals independent of their Ca2+ releasing ability. To address this, we generated IP3Rs triple and double knockout human embryonic kidney (HEK) cell lines (IP3Rs-TKO, IP3Rs-DKO), and systemically examined ER Ca2+ dynamics and CRAC channel activity in these cells. The results showed that the rate of ER Ca2+ leakage and refilling, as well as SOCE were all significantly reduced in IP3Rs-TKO cells. And these TKO effects could be rescued by over-expression of IP3R3. Further, results showed that the diminished SOCE was caused by NEDD4L-mediated ubiquitination of Orai1 protein. Together, our findings indicate that IP3R3 is one crucial player in coordinating ER-mediated Ca2+ signalling.

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Rabab, Kaneez E., Paul J. Buchanan, Grace Colley, et al. "TP53 Mutation-Specific Dysregulation of Store-Operated Calcium Entry and Apoptotic Sensitivity in Triple-Negative Breast Cancer." Cancers 17, no. 10 (2025): 1614. https://doi.org/10.3390/cancers17101614.

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Background: Triple-negative breast cancer (TNBC) is an aggressive subtype lacking estrogen, progesterone, and HER2 receptors, and is associated with poor prognosis and limited targeted therapeutic options. TP53 mutations occur in the majority of TNBC cases, disrupting p53’s role in DNA repair and apoptosis. Beyond gene regulation, p53 also influences calcium signalling through store-operated calcium entry (SOCE), a critical pathway for cell survival and death. However, the impact of different TP53 mutation types on calcium signalling remains unclear. Methods: Calcium channel gene expression was analysed using publicly available TNBC datasets. Calcium channel expression and SOCE activity were assessed in TNBC cell lines with different TP53 mutations using quantitative PCR and calcium imaging (Fura-2AM). Cell proliferation was measured using acid phosphatase assays, while apoptosis was evaluated through caspase 3/7 activation using the Incucyte live-cell fluorescent imager. The p53 reactivator COTI-2 was tested for its ability to restore TP53 function and modulate calcium signalling. Results: Analysis revealed significant downregulation of CACNA1D in TP53-mutant TNBCs. TNBC cell lines harbouring frameshift and stop TP53 mutations exhibited reduced SOCE, lower CACNA1D expression, and resistance to thapsigargin-induced apoptosis compared to wild-type cells. In contrast, cells with the TP53 R273H missense mutation demonstrated similar calcium signalling and proliferation to TP53 wild-type cels. COTI-2 treatment restored CACNA1D expression and SOCE in frameshift and stop mutant cells, enhancing apoptotic sensitivity. Combined treatment with COTI-2 and thapsigargin resulted in a synergistic increase in apoptosis. Conclusions: This study identifies a novel link between TP53 mutation type and calcium signalling in TNBC. Reactivating mutant p53 with COTI-2 restores calcium-mediated apoptosis, supporting combination strategies targeting both TP53 dysfunction and calcium signalling.

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Mehmood, Safdar, Jinshun Bi, Mengxin Liu, and Yu Zhang. "Simulation of Gallium Nitride/Aluminum Nitride-Based Triple Barrier Quantum Region for ULTRARAM Application." Journal of Nanoelectronics and Optoelectronics 18, no. 8 (2023): 897–904. http://dx.doi.org/10.1166/jno.2023.3468.

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ULTRARAM is a low-power, high-speed, nonvolatile compound semiconductor memory device that uses triple barrier resonance tunneling (TBRT) to store electrical charge in a floating gate. Using a self-consistent solution of Schrödinger-Poisson equations, we investigated the electrical properties, transmission spectra, and electron dynamics across GaN/AlN TBRT region for the ULTRARAM application. The simulation results show that GaN/AlN exhibits tunable electrical properties by using a TBRT region of variable thickness. Successive optimization and testing of various thicknesses significantly altered the transmission across multiple barriers and localization of electrons in the quantum wells. The program/erase (P/E) operation of GaN/AlN-based ULTRARAM in a triple barrier structure is accomplished at less than 2 V. The device’s excellent nonvolatility is due to the conduction band offset (CBO) of GaN/AlN heterostructure providing a large energy barrier (2.1 eV), which prevents electrons from escaping from the floating gate. Because of the low voltage operation and small capacitance, the switching energy consumption is much lower than that of a standard floating gate Flash.

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Saputro, Ronggo Bayu, Kurnia Paranita Kartika, and Wahyu Dwi Puspitasari. "Implementation of the Triple Exponential Smoothing Method for Predicting Helmet Sales." JOINCS (Journal of Informatics, Network, and Computer Science) 5, no. 2 (2022): 30–34. http://dx.doi.org/10.21070/joincs.v5i2.1607.

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Helmet stock at the Trend Helmet store is very important to prepare, because it is for the readiness of goods to be sold in the future. Therefore, it is necessary to do forecasting to find out the estimated stock in the future. The method that can be used to predict the stock of goods for several periods at once is Triple Exponential Smoothing. Helmet stock forecasting results with Cargloss helmet sales data obtained a forecast for 2022. Alpha, beta and gamma used in this study were 0.3. Cargloss helmet sales forecast results in January as many as 379, February as many as 449, March as many as 431, April as many as 500, May as many as 483, June as many as 552, July as many as 534, August as many as 604, September as many as 586, October as many as 656, November as many as 638 , December as many as 707. The results of the calculation of accuracy with Mean Absolute Percentage Error with Alpha, Beta and Gamma values of 0.3 are 44.4%. Based on the value of Mean Absolute Percentage Error helmet sales forecasting with Triple Exponential Smoothing method is feasible to use.

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Tauscher, H. "CREATING AND MAINTAINING IFC–CITYGML CONVERSION RULES." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences IV-4/W8 (September 23, 2019): 115–22. http://dx.doi.org/10.5194/isprs-annals-iv-4-w8-115-2019.

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Abstract. We employ a triple graph grammar to enable configurable conversion from IFC to CityGML. In this paper, we present the mathematical framework behind the graph transformation approach as well as an application to create, store and maintain transformation rules implementing this framework. Particular emphasis is put on how the approach enables graphical representation and static analysis of rules and rulesets, both in the theoretical framework and prototypical implementation. Even if various publications and tools for general graph transformation do already exist, we hope that the BIM–GIS community will benefit from a domain-specific introduction to the theory and dedicated software tools.

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Jardin, Isaac, Jose Lopez, Gines Salido, and Juan Rosado. "Store-Operated Ca2+ Entry in Breast Cancer Cells: Remodeling and Functional Role." International Journal of Molecular Sciences 19, no. 12 (2018): 4053. http://dx.doi.org/10.3390/ijms19124053.

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Breast cancer is the most common type of cancer in women. It is a heterogeneous disease that ranges from the less undifferentiated luminal A to the more aggressive basal or triple negative breast cancer molecular subtype. Ca2+ influx from the extracellular medium, but more specifically store-operated Ca2+ entry (SOCE), has been reported to play an important role in tumorigenesis and the maintenance of a variety of cancer hallmarks, including cell migration, proliferation, invasion or epithelial to mesenchymal transition. Breast cancer cells remodel the expression and functional role of the molecular components of SOCE. This review focuses on the functional role and remodeling of SOCE in breast cancer cells. The current studies suggest the need to deepen our understanding of SOCE in the biology of the different breast cancer subtypes in order to develop new and specific therapeutic strategies.

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Usharani, Chava, P. Venkata Krishna, Praveena Akki, V. Saritha, and Gitanjali J. "Secure Communication Model for Dynamic Task Offloading in Multi-Cloud Environment." International Journal on Recent and Innovation Trends in Computing and Communication 10, no. 10 (2022): 155–60. http://dx.doi.org/10.17762/ijritcc.v10i10.5744.

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As the data is increasing day-by-day, the mobile device storage space is not sufficient to store the complete information and also the computation capacity also is a limited resource which is not sufficient for performing all the required computations. Hence, cloud computing technology is used to overcome these limitations of the mobile device. But security is the main concern in the cloud server. Hence, secure communication model for dynamic task offloading in multi-cloud environment is proposed in this paper. Cloudlet also is used in this model. Triple DES with 2 keys is used during the communication process between the mobile device and cloudlet. Triple DES with 3 keys is used by the cloudlet while offloading the data to cloud server. AES is used by the mobile device while offloading the data to the cloud server. Computation time, communication time, average running time, and energy consumed by the mobile device are the parameters which are used to evaluate the performance of the proposed system, SCM_DTO. The performance of the proposed system, SCM_DTO is compared with ECDH-SAHE and is proved to be performing better.

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Wang, J., and J. Xiao. "Exact Finite Element Formulation of Frenet Formula of Curve in Geospatial Database." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-4 (April 23, 2014): 291–95. http://dx.doi.org/10.5194/isprsarchives-xl-4-291-2014.

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Directly using the difference form of Frenet formula will cause the three basic vectors losing their orthogonal features rapidly. As the analytic form is exact for infinite short length region, for finite length segregation, the omitted items should be retrieved to get high precision. Based on the unit orthogonal transformation in geometrical field theory, the Frenet formula is reformed for finite length region. Then, for given triple at the initial end of curve, using the curve parameters of curvature and torsion, the exact finite element formulation of Frenet formula is obtained to get the triples at any length position until the end point of curve. This method can be used as a high-precision technology for the measure, store, and retrieve of complicated curve.

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Cole, Tim, and Torsten Hahmann. "Geographies of the Holocaust: Experiments in GIS, QSR, and Graph Representations." International Journal of Humanities and Arts Computing 13, no. 1-2 (2019): 39–52. http://dx.doi.org/10.3366/ijhac.2019.0230.

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This article responds to the widespread and oft-noted challenges digital humanists face in working with data that is uncertain and characterised by complex narratives. Using an example drawn from the vast archives of post-war interviews with Holocaust survivors, it draws on approaches developed in Qualitative Spatial Representation (QSR) to explore how two key spatial aspects of survivor's narratives – their uncertain wartime trajectories and the slippage in scales as these are retold – can be represented. Spatial information in narratives tends to not provide the exact coordinates necessary to store the information in geospatial databases. Instead, narratives rely much more on often less precise qualitative spatial relations such as ‘near’, ‘next to’, ‘at the corner of’ without precise geometric interpretations. Given that relational databases are ill-equipped to store this kind of relational spatial knowledge from natural language sources, the article argues for a need for digital humanists to return to first principles and reconsider database design. Descriptive triple-based graph representations, which have been devised to accommodate this kind of highly irregular, semi-structured relational knowledge, have the potential to work with, rather than against, the grain of the narrative sources that underlie the work of much of the digital humanities.

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Bereta, K., G. Xiao, and M. Koubarakis. "ANSWERING GEOSPARQL QUERIES OVER RELATIONAL DATA." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W2 (July 5, 2017): 43–50. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w2-43-2017.

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In this paper we present the system Ontop-spatial that is able to answer GeoSPARQL queries on top of geospatial relational databases, performing on-the-fly GeoSPARQL-to-SQL translation using ontologies and mappings. GeoSPARQL is a geospatial extension of the query language SPARQL standardized by OGC for querying geospatial RDF data. Our approach goes beyond relational databases and covers all data that can have a relational structure even at the logical level. Our purpose is to enable GeoSPARQL querying on-the-fly integrating multiple geospatial sources, without converting and materializing original data as RDF and then storing them in a triple store. This approach is more suitable in the cases where original datasets are stored in large relational databases (or generally in files with relational structure) and/or get frequently updated.

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Pasek, Matthew. "Elements of life: The role of phosphorus in abiogenesis." Biochemist 36, no. 6 (2014): 9–12. http://dx.doi.org/10.1042/bio03606009.

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The element phosphorus performs several key roles in modern-day biochemistry. These include acting as a store of chemical energy in phosphate anhydride bonds such as ATP, linking together nucleosides as part of DNA and RNA, and separating cells from the outside environment as phospholipid membranes. Phosphorus is critical to these roles broadly due to capacity for a triple negative charge at high pH. At physiological pH, the charge on phosphate is typically -1 or -2, and the spare hydroxy group(s) may link to one or two organic compounds, forming a molecule with a net negative charge. This negative charge helps to ensure molecular stability in water by fending off hydrolysis of key bonds, increases solubility and inhibits diffusion, and provides a recognition element for binding as a molecular substrate to enzymes.

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Lee, Keon Jin, Jin Seok Woo, Ji-Hye Hwang, et al. "STIM1 negatively regulates Ca2+ release from the sarcoplasmic reticulum in skeletal myotubes." Biochemical Journal 453, no. 2 (2013): 187–200. http://dx.doi.org/10.1042/bj20130178.

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STIM1 (stromal interaction molecule 1) mediates SOCE (store-operated Ca2+ entry) in skeletal muscle. However, the direct role(s) of STIM1 in skeletal muscle, such as Ca2+ release from the SR (sarcoplasmic reticulum) for muscle contraction, have not been identified. The times required for the maximal expression of endogenous STIM1 or Orai1, or for the appearance of puncta during the differentiation of mouse primary skeletal myoblasts to myotubes, were all different, and the formation of puncta was detected with no stimulus during differentiation, suggesting that, in skeletal muscle, the formation of puncta is a part of the differentiation. Wild-type STIM1 and two STIM1 mutants (Triple mutant, missing Ca2+-sensing residues but possessing the intact C-terminus; and E136X, missing the C-terminus) were overexpressed in the myotubes. The wild-type STIM1 increased SOCE, whereas neither mutant had an effect on SOCE. It was interesting that increases in the formation of puncta were observed in the Triple mutant as well as in wild-type STIM1, suggesting that SOCE-irrelevant puncta could exist in skeletal muscle. On the other hand, overexpression of wild-type or Triple mutant, but not E136X, attenuated Ca2+ releases from the SR in response to KCl [evoking ECC (excitation–contraction coupling) via activating DHPR (dihydropyridine receptor)] in a dominant-negative manner. The attenuation was removed by STIM1 knockdown, and STIM1 was co-immunoprecipitated with DHRP in a Ca2+-independent manner. These results suggest that STIM1 negatively regulates Ca2+ release from the SR through the direct interaction of the STIM1 C-terminus with DHPR, and that STIM1 is involved in both ECC and SOCE in skeletal muscle.

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Vaisman, Alejandro, and Kevin Chentout. "Mapping Spatiotemporal Data to RDF: A SPARQL Endpoint for Brussels." ISPRS International Journal of Geo-Information 8, no. 8 (2019): 353. http://dx.doi.org/10.3390/ijgi8080353.

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This paper describes how a platform for publishing and querying linked open data for the Brussels Capital region in Belgium is built. Data are provided as relational tables or XML documents and are mapped into the RDF data model using R2RML, a standard language that allows defining customized mappings from relational databases to RDF datasets. In this work, data are spatiotemporal in nature; therefore, R2RML must be adapted to allow producing spatiotemporal Linked Open Data.Data generated in this way are used to populate a SPARQL endpoint, where queries are submitted and the result can be displayed on a map. This endpoint is implemented using Strabon, a spatiotemporal RDF triple store built by extending the RDF store Sesame. The first part of the paper describes how R2RML is adapted to allow producing spatial RDF data and to support XML data sources. These techniques are then used to map data about cultural events and public transport in Brussels into RDF. Spatial data are stored in the form of stRDF triples, the format required by Strabon. In addition, the endpoint is enriched with external data obtained from the Linked Open Data Cloud, from sites like DBpedia, Geonames, and LinkedGeoData, to provide context for analysis. The second part of the paper shows, through a comprehensive set of the spatial extension to SPARQL (stSPARQL) queries, how the endpoint can be exploited.

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Sanchez-Collado, Jose, Jose J. Lopez, Carlos Cantonero, et al. "Orai2 Modulates Store-Operated Ca2+ Entry and Cell Cycle Progression in Breast Cancer Cells." Cancers 14, no. 1 (2021): 114. http://dx.doi.org/10.3390/cancers14010114.

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Breast cancer is a heterogeneous disease from the histological and molecular expression point of view, and this heterogeneity determines cancer aggressiveness. Store-operated Ca2+ entry (SOCE), a major mechanism for Ca2+ entry in non-excitable cells, is significantly remodeled in cancer cells and plays an important role in the development and support of different cancer hallmarks. The store-operated CRAC (Ca2+ release-activated Ca2+) channels are predominantly comprised of Orai1 but the participation of Orai2 and Orai3 subunits has been reported to modulate the magnitude of Ca2+ responses. Here we provide evidence for a heterogeneous expression of Orai2 among different breast cancer cell lines. In the HER2 and triple negative breast cancer cell lines SKBR3 and BT20, respectively, where the expression of Orai2 was greater, Orai2 modulates the magnitude of SOCE and sustain Ca2+ oscillations in response to carbachol. Interestingly, in these cells Orai2 modulates the activation of NFAT1 and NFAT4 in response to high and low agonist concentrations. Finally, we have found that, in cells with high Orai2 expression, Orai2 knockdown leads to cell cycle arrest at the G0-G1 phase and decreases apoptosis resistance upon cisplatin treatment. Altogether, these findings indicate that, in breast cancer cells with a high Orai2 expression, Orai2 plays a relevant functional role in agonist-evoked Ca2+ signals, cell proliferation and apoptosis resistance.

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Jardin, Isaac, Raquel Diez-Bello, Jose Lopez, et al. "TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure." Cancers 10, no. 9 (2018): 331. http://dx.doi.org/10.3390/cancers10090331.

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Transient receptor potential channels convey signaling information from a number of stimuli to a wide variety of cellular functions, mainly by inducing changes in cytosolic Ca2+ concentration. Different members of the TRPC, TRPM and TRPV subfamilies have been reported to play a role in tumorigenesis. Here we show that the estrogen receptor positive and triple negative breast cancer cell lines, MCF7 and MDA-MB-231, respectively, exhibit enhanced expression of the TRPC6 channel as compared to the non-tumoral MCF10A cell line. In vitro TRPC6 knockdown using shRNA impaired MCF7 and MDA-MB-231 cell proliferation, migration and invasion detected by BrdU incorporation, wound healing and Boyden chamber assays, respectively. Using RNAi-mediated TRPC6 silencing as well as overexpression of the pore-dead dominant-negative TRPC6 mutant we have found that TRPC6 plays a relevant role in the activation of store-operated Ca2+ entry in the breast cancer cell lines but not in non-tumoral breast cells. Finally, we have found that TRPC6 interacts with Orai1 and Orai3 in MCF7 and MDA-MB-231 cells and is required for the translocation of Orai1 and Orai3 to the plasma membrane in MDA-MB-231 and MCF7 cells, respectively, upon Ca2+ store depletion. These findings introduce a novel mechanism for the modulation of Ca2+ influx and the development of different cancer hallmarks in breast cancer cells.

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Cantonero, Carlos, Pedro Javier Camello, Carmen Abate, et al. "NO1, a New Sigma 2 Receptor/TMEM97 Fluorescent Ligand, Downregulates SOCE and Promotes Apoptosis in the Triple Negative Breast Cancer Cell Lines." Cancers 12, no. 2 (2020): 257. http://dx.doi.org/10.3390/cancers12020257.

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(1) Background: The structure of the Sigma 2 receptor/TMEM97 (σ2RTMEM97) has recently been reported. (2, 3) Methods and results: We used genetic and biochemical approaches to identify the molecular mechanism downstream of σ2R/TMEM97. The novel σ2R/TMEM97 fluorescent ligand, NO1, reduced the proliferation and survival of the triple negative breast cancer cell lines (TNBC: MDA-MB-231 and MDA-MB-468 cell lines), due to NO1-induced apoptosis. Greater bioaccumulation and faster uptake of NO1 in MDA-MB-231 cells compared to MCF10A or MCF7 cell lines were also shown. Accordingly, elevated σ2R/TMEM97 expression was confirmed by Western blotting. In contrast to NO1, other σ2R/TMEM97 ligands, such as SM21 and PB28, enhanced MDA-MB-231 cell proliferation and migration. Store-operated calcium entry (SOCE) is crucial for different cancer hallmarks. Here, we show that NO1, but not other σ2R/TMEM97 ligands, reduced SOCE in MDA-MB-231 cells. Similarly, TMEM97 silencing in MDA-MB-231 cells also impaired SOCE. NO1 administration downregulated STIM1-Orai1 interaction, probably by impairing the positive regulatory effect of σ2R/TMEM97 on STIM1, as we were unable to detect interaction with Orai1. (4) Conclusion: σ2R/TMEM97 is a key protein for the survival of triple negative breast cancer cells by promoting SOCE; therefore, NO1 may become a good pharmacological tool to avoid their proliferation.

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B. Kala and D. Arulanantham. "Multi-Bit Error Resilient FPGA Cram with Minimum TTD." International Research Journal on Advanced Engineering Hub (IRJAEH) 2, no. 06 (2024): 1551–57. http://dx.doi.org/10.47392/irjaeh.2024.0212.

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In harsh environments such as space, radiation and charged particles cause Single-Event and Multi-bit Effects, faults occurring randomly on any electronic component. These must be mitigated to ensure device functionality. Modern mitigation methods, such as triple modular redundancy, are very effective against Single Event Transients (SETs), but incur a minimum of 3× cost in area. Single-Event Upsets (SEUs) affect sequential elements and are regularly repaired using memory scrubbing. Scrubbing is a slow serial process, going through every memory word looking for errors to repair. It involves a non-negligible Time to Detect (TTD) before repair, during which other events can occur and compromise the system. Field Programmable Gate Arrays (FPGAs) rely heavily on sequential elements to store their configuration; thus, FPGA’s SEU detection time is critical to ensuring design integrity in harsh conditions. It is required a robust error correction code (ECC) to protect electronic devices from MCUs. The proposed work describes the conception, implementation and evaluation of new algorithm using matrix code for the detection and correction of multiple errors in FPGA configuration memories. The combined architecture with multiple bit segment with parity bits helps in locating and correcting double-triple bit errors. The proposed Method allows asynchronous MEU detection and replaces scrubbing variable time to detect with a fixed TTD. The IMECCC based on Matrix code reduces FPGA’s TTD compared to existing method.

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Vogt, Lars, and Roman Baum. "Using Named Graphs and Knowledge Graph Template Patterns for Efficiently Organizing FAIR Anatomy Data and Metadata." Biodiversity Information Science and Standards 3 (June 19, 2019): e37205. https://doi.org/10.3897/biss.3.37205.

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Currently, morphological data and metadata are still mostly published as unstructured free texts, which lack semantic transparency, cannot be parsed by computers, and do not comply with the FAIR (Findable, Accessible, Interoperable, Reusable; Wilkinson et al. (2016) data principles, thus hampering their reuse by non-experts and their integration across many fields in the life sciences. With an ever-increasing amount of available ontologies and the development of adequate semantic technology, however, a solution to this problem becomes available. Instead of free text descriptions, morphological data and metadata can be recorded, stored, and communicated through the Web in the form of Resource Description Framework (RDF) triple statements that use the 'Subject – Property – Object' syntax of RDF and URIs of ontology classes and properties as well as URIs for individual entities as terminology. Since a given URI can take the 'Subject' position in one and the 'Object' position in another RDF statement, several triples can be linked to form a highly formalized and structured directed graph (semantic graph). After introducing an instance-based approach of recording morphological descriptions and their accompanying metadata as semantic knowledge graphs (i.e. Anatomy Knowledge Graphs), we propose a knowledge graph template pattern for each type of anatomical observation and a pattern for documenting metadata. The use of template patterns for knowledge graphs provides Interoperability and Reusability of comparable anatomical observations and of their accompanying metadata and a means to meaningfully visualize information contained in semantic graphs in a user-friendly HTML representation. Stored in a tuple store, Anatomy Knowledge Graphs become Findable and Accessible through the store's SPARQL endpoint. As a consequence, anatomy data and metadata documented as Anatomy Knowledge Graphs in a tuple store are FAIR. Finally, we suggest a general scheme of how to efficiently organize Anatomy Knowledge Graphs in a tuple store framework based on instances of named graphs, with each individual named graph instantiating an ontology class that relates to a particular type of observation (e.g., weight measurement named graph class). A named graph is a fourth element in an RDF statement ('Subject – Property – Object – Named Graph'), turning the triple into a quadruple. All RDF statements that share the same URI in the 'Named Graph' position belong to the same named graph. The use of named graph resources allows meaningful fragmentation of the contents of an Anatomy Knowledge Graph (Fig. 1), which in turn enables subsequent specification of all kinds of data views for managing and accessing morphological data and metadata. This scheme has been implemented in the description module of the prototype for semantic Morph∙D∙Base.

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Adlany, Nizar, Said Salim Dahda, and Moh Jufriyanto. "Implementasi Seven Tools Of Quality Di Industri Kecil Triple X Produksi Tas." JATI EMAS (Jurnal Aplikasi Teknik dan Pengabdian Masyarakat) 6, no. 2 (2022): 9. http://dx.doi.org/10.36339/je.v6i2.569.

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Bags are accessories that are often used by students and workers to store their belongings. In Indonesia, there are many bag craftsmen and they have various qualities. Triple X SME is a small micro business and is classified as a bag production house industry. Maintaining quality consistency is a problem that occurs along the bag production line. Quality problems if not resolved will result in an increase in the cost of making the bag. Then the seven tools (7QC) one of the proven methods in dealing with this and as a result of the seven quality control instruments (7QC) reducing the number of manufacturing-related errors. These devices have proven to be quite useful in terms of increasing output and improving quality. As this case study can show, when 7QC techniques are used in a small business, they help deal with the problems experienced by the SME. During the first six months of the project, production lines are inspected, faults are categorized, and 7QC tools are implemented effectively and problems found exactly. As important as any tool in finding the root cause of a problem is, a cause and effect diagram is the most important.

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Gmür, Reto, and Donat Agosti. "Synospecies, an application to reflect changes in taxonomic names based on a triple store based on taxonomic data liberated from publication." Biodiversity Information Science and Standards 5 (September 23, 2021): e75641. https://doi.org/10.3897/biss.5.75641.

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Taxonomic treatments, sections of publications documenting the features or distribution of a related group of organisms (called a "taxon", plural "taxa") in ways adhering to highly formalized conventions, and published in scientific journals, shape our understanding of global biodiversity (Catapano 2019).Treatments are the building blocks of the evolving scientific consensus on taxonomic entities. The semantics of these treatments and their relationships are highly structured: taxa are introduced, merged, made obsolete, split, renamed, associated with specimens and so on. Plazi makes this content available in machine-readable form using Resource Description Framework (RDF) . RDF is the standard model for Linked Data and the Semantic Web. RDF can be exchanged in different formats (aka concrete syntaxes) such as RDF/XML or Turtle. The data model describes graph structures and relies on Internationalized Resource Identifiers (IRIs) , ontologies such as Darwin Core basic vocabulary are used to assign meaning to the identifiers. For Synospecies, we unite all treatments into one large knowledge graph, modelling taxonomic knowledge and its evolution with complete references to quotable treatments. However, this knowledge graph expresses much more than any individual treatment could convey because every referenced entity is linked to every other relevant treatment. On synospecies.plazi.org, we provide a user-friendly interface to find the names and treatments related to a taxon. An advanced mode allows execution of queries using the SPARQL query language.

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Osei-Asibey, Ryan Kusi, Faustina Dufie Wireko-Manu, Robert Aidoo, Stanley Boakye-Achampong, Felix Charles Mills-Robertson, and Dieudonne Baributsa. "Farmers’ Perception of the Use and Benefits of Cowpea Storage Methods in Northern Ghana." Sustainability 14, no. 9 (2022): 5129. http://dx.doi.org/10.3390/su14095129.

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Insect infestation during the storage of cowpea is a major challenge among smallholder farmers in sub-Saharan Africa (SSA). Farmers use various postharvest storage methods to deal with insect pests, including insecticides, which may result in health and environmental hazards. Four hundred (400) cowpea farmers were interviewed on their perceptions and preference of different storage methods in Northern Ghana. About 58% of farmers applied insecticides, 50% used ash, and 42% used hermetic triple-layer bags (Purdue Improved Crop Storage, PICS) to store cowpea. Most farmers (85.6%) preferred the PICS technology for its effectiveness (compared to insecticides, ash, and botanicals). Reasons for the non-use of PICS bags included unavailability (39.5%) and high price (11.7%). Farmers perceived that storing cowpea in PICS bags lowered pesticide-related health risks for both farmers and consumers. Thus, there is a need to improve the availability and affordability of PICS bags in Northern Ghana.

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Osei-Asibey, Ryan Kusi, Faustina Dufie Wireko-Manu, Robert Aidoo, Stanley Boakye-Achampong, Felix Charles Mills-Robertson, and Dieudonne Baributsa. "Farmers’ Perception of the Use and Benefits of Cowpea Storage Methods in Northern Ghana." Sustainability 14, no. 9 (2022): 5129. http://dx.doi.org/10.3390/su14095129.

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Insect infestation during the storage of cowpea is a major challenge among smallholder farmers in sub-Saharan Africa (SSA). Farmers use various postharvest storage methods to deal with insect pests, including insecticides, which may result in health and environmental hazards. Four hundred (400) cowpea farmers were interviewed on their perceptions and preference of different storage methods in Northern Ghana. About 58% of farmers applied insecticides, 50% used ash, and 42% used hermetic triple-layer bags (Purdue Improved Crop Storage, PICS) to store cowpea. Most farmers (85.6%) preferred the PICS technology for its effectiveness (compared to insecticides, ash, and botanicals). Reasons for the non-use of PICS bags included unavailability (39.5%) and high price (11.7%). Farmers perceived that storing cowpea in PICS bags lowered pesticide-related health risks for both farmers and consumers. Thus, there is a need to improve the availability and affordability of PICS bags in Northern Ghana.

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Yoo, Choong-Shik. "Barochemistry to Multifunctional High Energy Density Solid: Extended Phases of N2, CO, and N2+CO at High Pressures." MRS Advances 2, no. 48 (2017): 2581–86. http://dx.doi.org/10.1557/adv.2017.382.

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ABSTRACTMany simple diatomic and triatomic molecules such as N2 and CO2 have the potential to form extended “polymeric” solids under extreme conditions, which can store a large sum of chemical energy in its three-dimensional network structures made of strong covalent bonds. Diatomic nitrogen is particularly of interest because of the uniquely large energy difference between that of the single bond (160 kJ/mol) and that of the triple bond (954 kJ/mol). As such, the transformation of a singly bonded polymeric nitrogen back to triply-bonded diatomic nitrogen molecules can release nearly 5 times the energy of TNT without any negative environmental impact. In this paper, we will describe our recent research efforts to synthesize novel extended phases of isoelectronic systems of N2 and CO, as well as those of N2+CO mixtures to lower the transition pressures and enhance the stability of recovered products at ambient condition.

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Liao, XiFeng. "Frameworks for Developing a 6G Communication Network to Intensify the Modern Vocational Education System." International Journal of Information and Communication Technology Education 20, no. 1 (2023): 1–19. http://dx.doi.org/10.4018/ijicte.335119.

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A modern technology-supported vocational educational system significantly affects the quality of vocational training and contributes to the innovation and economic development of the regional area. The visualization literature analysis was adopted with the purpose of exploring the theoretical framework for developing a 6G-assisted network to realize the multi-party participation in the modern government-industry-education Integration system. The literature review showed the network should involve all cooperation entities into the communication system to intensify all coordination guided by the triple helix theory, should be strong enough to store all kinds of resources to support the optimized sharing, be efficient to track student training processes and learning data to provide scientific evaluation to student development in personal qualities and competencies, be supportive to develop a cooperating culture to form a healthy ecosystem in which all enterprises actively participate and invest in vocational education.

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Lawrence, Brian, and Juan Carlos Melgar. "Harvest, Handling, and Storage Recommendations for Improving Postharvest Quality of Blackberry Cultivars." HortTechnology 28, no. 5 (2018): 578–83. http://dx.doi.org/10.21273/horttech04062-18.

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Maintaining shelf life and postharvest quality of blackberries (Rubus subgenus Rubus) from harvest to consumer is challenging for growers and packers due to several postharvest issues including fresh weight (FW) loss, red drupelet reversion, and fruit leakiness. The time of day blackberries are harvested, the time from harvest to cold storage, and the time in cold storage are factors that may alter the incidence and severity of these postharvest problems. In this experiment, blackberries from 10 cultivars were picked at two different times (7:00–7:30 am and 10:00–10:30 am), delivered to cold storage either immediately or following a 90-minute delay, and evaluated after 1 or 2 weeks in cold storage for FW loss, red drupelet reversion, and leakiness. The response of blackberry postharvest quality to time of harvest, delay to cold storage, and storage length was cultivar-specific. In summary, time of harvest, delay to cold storage or storage length did not affect cultivars Arapaho and Ouachita. Different harvest times did not affect FW or incidence of reddening, but increased leakiness in ‘Chester’ and ‘Triple Crown’; thus, these two cultivars should be preferably harvested early in the morning. Our recommendation for ‘Chester’, ‘Triple Crown’, ‘Osage’, ‘Prime-Ark® Traveler’, and ‘Von’ is to store the fruit of these cultivars as soon as possible. Limiting cold storage to 1 week maintained postharvest quality for at least one attribute of most cultivars (all but Arapaho and Ouachita) compared with 2 weeks of storage.

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M. Al Assaf, Maen, Mohammad Qatawneh, and AlaaAldin AlRadhi. "Linear algorithm for data retrieval performance optimization in self-encryption hybrid data centers." Bulletin of Electrical Engineering and Informatics 14, no. 3 (2025): 2288–99. https://doi.org/10.11591/eei.v14i3.9320.

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Contemporary data centers implement hybrid storage systems that consist of layers from solid-state drives (SSDs) and hard disk drives (HDDs). Due to their high data retrieval speed, SSDs layer is used to store important data blocks that have features like high frequency of access. To boost their security level, many of such systems implement self-encryption algorithms like advanced encryption standard (AES), Blowfish, and triple data encryption standard (3DES) with different key sizes that vary in their complexity and their decryption latency whenever a block is requested for read. Frequently accessed data blocks with increased decryption latencies are better to be migrated to the SSDs layer to decrease their retrieval latency. In this paper, we introduce a linear complexity algorithm hybrid self-encryption storage data migration (HSESM) that migrates important data blocks that requires long decryption latencies from the HDDs layer to the SSDs one. Performance evaluation shows that HSESM data migration process can reduce data blocks read latencies in 13.71%-23.61% under worst-case scenarios.

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Jardin, Isaac, Joel Nieto-Felipe, Sandra Alvarado, et al. "SARAF and EFHB Modulate Store-Operated Ca2+ Entry and Are Required for Cell Proliferation, Migration and Viability in Breast Cancer Cells." Cancers 13, no. 16 (2021): 4160. http://dx.doi.org/10.3390/cancers13164160.

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Breast cancer is among the most common malignancies in women. From the molecular point of view, breast cancer can be grouped into different categories, including the luminal (estrogen receptor positive (ER+)) and triple negative subtypes, which show distinctive features and, thus, are sensitive to different therapies. Breast cancer cells are strongly dependent on Ca2+ influx. Store-operated Ca2+ entry (SOCE) has been found to support a variety of cancer hallmarks including cell viability, proliferation, migration, and metastasis. The Ca2+ channels of the Orai family and the endoplasmic reticulum Ca2+ sensor STIM1 are the essential components of SOCE, but the extent of Ca2+ influx is fine-tuned by several regulatory proteins, such as the STIM1 modulators SARAF and EFHB. Here, we show that the expression and/or function of SARAF and EFHB is altered in breast cancer cells and both proteins are required for cell proliferation, migration, and viability. EFHB expression is upregulated in luminal and triple negative breast cancer (TNBC) cells and is essential for full SOCE in these cells. SARAF expression was found to be similar in breast cancer and pre-neoplastic breast epithelial cells, and SARAF knockdown was found to result in enhanced SOCE in pre-neoplastic and TNBC cells. Interestingly, silencing SARAF expression in ER+ MCF7 cells led to attenuation of SOCE, thus suggesting a distinctive role for SARAF in this cell type. Finally, we used a combination of approaches to show that molecular knockdown of SARAF and EFHB significantly attenuates the ability of breast cancer cells to proliferate and migrate, as well as cell viability. In aggregate, SARAF and EFHB are required for the fine modulation of SOCE in breast cancer cells and play an important role in the maintenance of proliferation, migration, and viability in these cells.

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Achour, Mohamad, Mohamad Toufaily, Ludovic Avril, Gilles Betis, and Nisrine Makhoul. "Evaluating Environmental Impacts of Urban Development Strategies: A Case Study of the Fontaine d’Ouche District." Applied Sciences 14, no. 22 (2024): 10740. http://dx.doi.org/10.3390/app142210740.

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Life cycle assessment (LCA) is a methodology used to analyze the environmental impacts of a product. Initially, it was applied to buildings only, but recently, it has also been applied to entire neighborhood. This expansion from individual buildings to the neighborhood scale requires additional inputs, such as the impacts of public spaces, transportation, public network systems, and roads. Additionally, conducting an LCA for a neighborhood requires software tools to simulate the neighborhood and databases to store the environmental impacts of all the components integrated into the neighborhood. This paper presents an LCA case study of a neighborhood in Dijon, France. The study aims to analyze the thermal impacts of buildings and the neighborhood with single-, double-, and triple-pane windows. The second part of the study involves two LCA studies using the 1996 version of ecoinvent. The first study is a continuation of the thermal simulation analysis, while the second study compares concrete, masonry, and timber-based construction designs for the neighborhoods. The results show that the heating demands inside the buildings are substantially reduced when transitioning from single- to triple-pane, while the cooling demands show the opposite effect. Furthermore, doubling the width of double-pane windows resulted in less profound environmental damage for the construction, use, and demolition phases compared to single-pane windows, with only the renovation phase being more damaging. Additionally, the comparison between different construction scenarios shows that the timber-based variant is slightly advantageous from an environmental point of view compared to the concrete and masonry designs.

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Journal articles on the topic 'Triple-store'

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