Academic literature on the topic 'Trisubstituted'

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Journal articles on the topic "Trisubstituted"

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Mohrle, Hans, Thomas Platzek, Romanus Wille, and Detlef Wendisch. "Trisubstituted Cyclohexanes / Trisubstituted Cyclohexanes." Zeitschrift für Naturforschung B 40, no. 4 (1985): 524–33. http://dx.doi.org/10.1515/znb-1985-0415.

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C-Tertiarv vinylketones or the corresponding masked vinylketone derivatives react with pyrrolidin-2-one in the system sodium hydride.dimethylsulfoxide to substituted cyclohexanes of the 1,3.5- and sometimes additionally of the 1,2.4-type. Only acetophenone Mannich bases bear­ing a p-hydroxy or a dimethylamino group failed in cyclization.
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Arora, Pragi, Jagdeep Dua, and Jitender Singh. "Synthesis of some new 1,3,5-trisubstituted pyrazoles as antioxidant and antiinflammatory agents." Journal of Drug Delivery and Therapeutics 9, no. 2-s (2019): 343–47. http://dx.doi.org/10.22270/jddt.v9i2-s.2722.

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A series of some new 1,3,5-trisubstituted pyrazoles was synthesized by the reaction of α-β dibromochalcones with phenylhydrazine hydrochloride. α-β-Dibromochalcones were prepared by the regioselective bromination of respective chalcones with tetrabutylammonium tribromide. The synthesized trisubstituted pyrazoles were evaluated for their anti-inflammatory and antioxidant properties. Keywords: α-β-Dibromochalcones, 1,3,5-Trisubstituted pyrazoles, Tetrabutylammonium tribromide, Anti-inflammatory and antioxidant activities
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Morávková, Zuzana, Jiří Podešva, Valeriia Shabikova, Sabina Abbrent, and Miroslava Dušková-Smrčková. "Hydrogen Bonding of Trialkyl-Substituted Urea in Organic Environment." Molecules 30, no. 7 (2025): 1410. https://doi.org/10.3390/molecules30071410.

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Urea groups appear in many biomolecules and polymers. They have a significant impact on the properties of the materials because of their inherent strength and for their ability to participate in hydrogen bonds. Typically, in classical urea-based polymer materials, the urea groups occur in their N,N′-disubstituted state. Recently, bis-aspartates have been introduced as a novel type of hindered amine resins providing, upon crosslinking with (poly)isocyanates, the polyurea–polyaspartate thermosets (PU-ASPE) for coatings, sealants, polyelectrolytes, and other applications. These materials contain
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Gülten, Ş. "The Ugi Four-Component Reaction: Application in the synthesis of bis-hydantoins." Bulgarian Chemical Communications 56, no. D1 (2024): 13–18. http://dx.doi.org/10.34049/bcc.56.d.s2l4.

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Three new bis 1,3,5-trisubstituted hydantoins were synthesized by combining an Ugi four-component condensation reaction with a base induced cyclization. In the two-step sequence, first three new bis Ugi compounds were synthesized by the Ugi four-component condensation reaction, and then bis 1,3,5-trisubstituted hydantoins were obtained by intramolecular cyclization reaction.
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Sakhdari, Mahnaz, Ali Amoozadeh, and Eskandar Kolvari. "Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions." Heterocyclic Communications 27, no. 1 (2021): 71–78. http://dx.doi.org/10.1515/hc-2020-0125.

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Abstract In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40–70 min for trisubstituted imidazoles and 30–40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92–98% for trisubstituted imidazoles and 94–98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free con
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Sakhdari, Mahnaz, Ali Amoozadeh, and Eskandar Kolvari. "Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions." Heterocyclic Communications 27, no. 1 (2021): 71–78. http://dx.doi.org/10.1515/hc-2020-0125.

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Abstract In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40–70 min for trisubstituted imidazoles and 30–40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92–98% for trisubstituted imidazoles and 94–98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free con
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Sarshar, Sepehr, Chengzhi Zhang, Edmund J. Moran, et al. "2,4,5-Trisubstituted imidazoles." Bioorganic & Medicinal Chemistry Letters 10, no. 23 (2000): 2599–601. http://dx.doi.org/10.1016/s0960-894x(00)00520-5.

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Zhang, Chengzhi, Sepehr Sarshar, Edmund J. Moran, et al. "2,4,5-Trisubstituted imidazoles." Bioorganic & Medicinal Chemistry Letters 10, no. 23 (2000): 2603–5. http://dx.doi.org/10.1016/s0960-894x(00)00521-7.

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Rogers, Miriam E., and Bruce A. Averill. "Symmetrically trisubstituted triptycenes." Journal of Organic Chemistry 51, no. 17 (1986): 3308–14. http://dx.doi.org/10.1021/jo00367a011.

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Diederich, François, Corinne Baumgartner, and Lukas Brändli. "Synthesis of 1,2,4-Trisubstituted Imidazoles and 1,3,5-Trisubstituted 1,2,4-Triazoles." HETEROCYCLES 76, no. 1 (2008): 401. http://dx.doi.org/10.3987/com-08-s(n)21.

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Dissertations / Theses on the topic "Trisubstituted"

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Dixon, Nicholas John. "Stereoselective synthesis of trisubstituted alkenes." Thesis, University of Southampton, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.255821.

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Cariou, Claire. "Diastereoselective synthesis of 2,4,5-trisubstituted piperidines." Thesis, University of Birmingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434701.

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Bergman, Zara Dominique. "2,3,4-trisubstituted piperidines : a stereocontolled approach." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5794/.

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This thesis details a methodology utilising various synthetic pathways towards cyclisation precursors suitable for use in Prins and carbonyl-ene cyclisations to effect 2,3,4-trisubstituted piperidines. Once the precursors were synthesised, we were interested in the stereochemical outcomes of the cyclisations, in particular identity and rational of the kinetic and thermodynamic products and their variation due to differing substituents on C2. Previous work in the Snaith group has addressed various other substitution patterns and 2,3,4-trisubstituted piperidines are central components of a vast
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Feuillet, Frederic. "Stereoselective synthesis of (E)-trisubstituted acid derivatives." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397111.

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Troutman, Malisa V. (Malisa Vaughn) 1970. "Asymmetric hydrogenation of unfunctionalized trisubstituted and tetrasubstituted olefins." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9636.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1998.<br>Includes bibliographical references (leaves 97-98).<br>A highly reactive chiral catalyst for the asymmetric hydrogenation of aryl trisubstituted olefins was generated by combining the complex (EBTHI)MMe2 (EBTHI = ethylenebistetrahydroindenyl, M = Ti, Zr) with [PhMe2NH]+[(BC6F5)4]- under a hydrogen atmosphere. A number of unfunctionalized trisubstituted olefins could be hydrogenated rapidly at room temperature under 80 psig H2 with a wide range of ee's (7 97% ). Reduction of some substrates under a deuterium a
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Gunn, Andrew Fraser. "Trisubstituted η³-allyl molybdenum complexes : synthetic studies towards ebelactone." Thesis, University of Leeds, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396740.

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Repasky, Paul J. "Novel Trisubstituted Arylidene Oxindoles with Potent Anti-Apoptotic Properties." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1310326721.

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Pimm, Austen David. "The application of #alpha#-metallated heterosubstituted alkenes to trisubstituted alkene synthesis." Thesis, University of Southampton, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332548.

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Sadler, Matthew James. "Diastereoselective synthesis of 2,4,5 trisubstituted piperidines : application in natural product synthesis." Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/2901/.

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This thesis describes the diastereoselective synthesis of 2,4,5-trisubstituted piperidines using carbonyl-ene and Prins cyclisations and their application in natural product synthesis. Following on from previous work in the group, we investigated how a preinstalled substituent in the 2-position can help to control the sense of induction at the two newly forming stereocentres. We utilised the Prins reaction in the formal synthesis of pseudodistomin F, a marine alkaloid that posses a 2,4,5-tribsubstituted piperidine core. An initial first generation synthesis focused on the construction of a cyc
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Qin, Can. "Synthesis of Trisubstituted α,β-Unsaturated Esters through Catalytic Stereoretentive Cross-Metathesis:". Thesis, Boston College, 2021. http://hdl.handle.net/2345/bc-ir:109197.

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Thesis advisor: Amir H. Hoveyda<br>We have devised a broadly applicable catalytic cross-metathesis method for stereoretentive synthesis of Z- and E-trisubstituted α,β-unsaturated esters. Several new Mo-bisaryloxide complexes were prepared, and they showed superior efficiency in synthesizing the Z-trisubstituted enoates (vs. corresponding mono-aryloxide pyrrolide complexes). Synthetic utility of the method was demonstrated through several concise syntheses of bioactive triterpenoids and value-added derivatives of prenyl-containing compounds such as citronellal, citronellol, and geraniol, all of
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Books on the topic "Trisubstituted"

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Shrestha-Dawadi, Prativa Bade. The intermediacy of nitrilium salts in the Beckmann rearrangement ; Synthesis of nitrilium salts from nitriles and chloroformates ; Preparation of 3,4,5-trisubstituted 1,2,4-oxadiazolium salts from nitrilium salts and nitrile oxides. Hartung-Gorre, 1993.

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Book chapters on the topic "Trisubstituted"

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Davies, A. G. "16.2.2.4 Trisubstituted 1,4-benzosemiquinones." In Phosphorus-Centered Radicals, Radicals Centered on Other Heteroatoms, Organic Radical Ions. Part 2. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-87641-0_15.

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Davies, A. G. "16.2.1.6 Trisubstituted 1,2-benzosemiquinones." In Phosphorus-Centered Radicals, Radicals Centered on Other Heteroatoms, Organic Radical Ions. Part 2. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-87641-0_9.

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Sisler, Harry H., George Omietanski, Charles J. A. Volz, and Bernard Rudner. "1,1,1-Trisubstituted Hydrazonium Chlorides." In Inorganic Syntheses. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132364.ch25.

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Mignani, S., Y. Zhou, T. Lecourt, and L. Micouin. "Recent Developments in the Synthesis 1,4,5-Trisubstituted Triazoles." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/7081_2011_68.

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Heine, Niklas, Jens Schneider-Mergener, and Holger Wenschuh. "SPOT Synthesis of 1,3,5-Trisubstituted Hydantoins on Cellulose Membranes." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_268.

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Hirschmann, H. "The Characterization of Trisubstituted Steroidal Olefines by Infra-Red Spectroscopy." In Ciba Foundation Symposium - Synthesis and Metabolism of Adrenocortical Steroids (Colloquia on Endocrinology, Vol. 7). John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/9780470718865.ch10.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(III) complex with 2,6,9-trisubstituted purine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_96.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(III) complex with 2,6,9-trisubstituted purine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_97.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(III) complex with 2,6,9-trisubstituted purine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_99.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of iron(III) complex with 2,6,9-trisubstituted purine." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 8. Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-66460-5_100.

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Conference papers on the topic "Trisubstituted"

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Majerova, Petra, Ivana Gerhardtova, Eva Havrankova, Timotej Jankech, Andrej Kovac, and Josef Jampilek. "Trisubstituted 1,3,5-Triazines and Their Effect on BACE1." In ECSOC 2023. MDPI, 2023. http://dx.doi.org/10.3390/ecsoc-27-16111.

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Karskela, Tuomas, and Harri Lönnberg. "A facile solid-phase synthesis of 5,1',5'-trisubstituted 2,4'-biimidazoles." In XIVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810372.

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Kaufman, Teodoro, and Marcela Amongero. "ORGANOCATALYTIC APPROACH TO THE SYNTHESIS OF OPTICALLY ACTIVE 1,2,3-TRISUBSTITUTED AZETIDINES." In The 13th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2009. http://dx.doi.org/10.3390/ecsoc-13-00211.

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Khalifa, Abdulrhman Y., Mahmood Sh Magtoof та Husam M. Kredy. "Synthesis, spectral characterization, antioxidant and anticancer evaluation of 1, 2, 3-trisubstituted-γ-lactams". У PROCEEDING OF THE 1ST INTERNATIONAL CONFERENCE ON ADVANCED RESEARCH IN PURE AND APPLIED SCIENCE (ICARPAS2021): Third Annual Conference of Al-Muthanna University/College of Science. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0093789.

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Pereira, Vera L. Patrocinio, Jeronimo da Silva Costa, Alessandra C. de Souza e. Silva, and Fernanda Cunha do Nascimento. "A versatile synthesis to trisubstituted nitroalkenes via nitroaldol reaction: Synthesis of Baylis-Hillman type adducts." In 15th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-15bmos-bmos2013_2013819161427.

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Welsh, William J., Youyi Peng, Jyoti Joshi Mundra, et al. "Abstract 1626: Novel trisubstituted triazoles modeled from naltrindole inhibit the proliferation of human multiple myeloma cells." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1626.

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Cahyana, A. H., B. Ardiansah, and A. Mubardiani. "CoFe2O4 magnetic catalyst assisted a facile one-pot multicomponent construction of 2,4,5-trisubstituted-1H-imidazole derivatives." In PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES 2017 (ISCPMS2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5064054.

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Maleki, Ali, and Zahra Alirezvani. "A Highly Efficient Synthesis of 2,4,5-Trisubstituted Imidazoles Catalyzed by Composite Magnetic Nanoparticle Under Mild Reaction Conditions." In The 18th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a003.

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Abood, Zeid Hassan, Hayder Raheem Ali, and Hussein Ali Qabel. "Microwave synthesis of 2,3,5-trisubstituted-1,3-imidazolidin-4-ones bearing 1,3,4-oxadiazole moiety and preliminary evaluation of their antibacterial activity." In THE 7TH INTERNATIONAL CONFERENCE ON APPLIED SCIENCE AND TECHNOLOGY (ICAST 2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5123064.

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El-Awaad, Ehab, Robin Birus, Laurens Ballentin, et al. "Biological evaluation of 4,5,7-trisubstituted Indeno[1,2-&lt;em&gt;b&lt;/em&gt;]indoles reveals a potent inhibitor of protein kinase CK2 in tumor cells with diverse anti-cancer effects and preferential cytoplasmic localization." In 7th International Electronic Conference on Medicinal Chemistry. MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11450.

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