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Journal articles on the topic 'Trophic deficiency'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Komarova, L. N., and K. U. Nabieva. "Clinical case of venous trophic ulcer treatment." Medical Science And Education Of Ural 22, no. 4 (2021): 94–97. http://dx.doi.org/10.36361/1814-8999-2021-22-4-94-97.

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Introduction. Varicose veins of the lower extremities with clinical form C2 and higher (if we take into account the modern international classification) is a slowly progressive disease. It needs therapy, besause if untreated, some complications can develop, such as: trophic disorders (lipodermatosclerosis, skin hyperpigmentation, trophic ulcers), bleeding from varicose veins with minimal trauma, thrombotic complications (varicothrombophlebitis, deep vein thrombosis, pulmonary embolism). Materials and methods. This article presents a description of a clinical case of an aged patient with a trop

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2

Rattan, Kim J., William D. Taylor, and Ralph E. H. Smith. "Nutrient status of phytoplankton across a trophic gradient in Lake Erie: evidence from new fluorescence methods." Canadian Journal of Fisheries and Aquatic Sciences 69, no. 1 (2012): 94–111. http://dx.doi.org/10.1139/f2011-135.

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Variable fluorescence of chlorophyll a was measured by pulse amplitude modulated fluorometry to determine its relationship with measures of nutrient status and phytoplankton community structure in Lake Erie. In 2005, nitrogen (N) deficiency was most common in May, phosphorus (P) deficiency was most common in June, and neither were common in September. The maximum quantum yield (Fv/Fm) measured by pulse amplitude modulated fluorometry was lower in May and June than in September. The observed range of Fv/Fm included many values lower than previously reported in the lower Laurentian Great Lakes,

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Berezkin, Victor Yu, Victor V. Glebov, and Elena P. Kayukova. "The factors of the low iodine concentration in soil cover and drinking waters of the second ridge of the Mountain Crimea." RUDN Journal of Ecology and Life Safety 31, no. 4 (2023): 521–32. http://dx.doi.org/10.22363/2313-2310-2023-31-4-521-532.

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Low iodine content in the environment can be one of the main factors of iodine deficiency diseases in humans and farm animals, including hypothyroidism, nodular thyroid tumors, irreversible brain damage in the fetus and newborn. Endemic goiter, caused primarily by iodine deficiency, is an urgent problem for most regions of modern Russia, including the Republic of Crimea. For the Republic of Crimea, along with other regions of the Crimean-Caucasian mountain zone, there is a deficiency of iodine in the lower links of the trophic chain, which provokes iodine deficiency diseases. The aim of the wo

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Han, Xinran. "Nuclear Pollution and Its Effects on Marine Ecosystems." Highlights in Science, Engineering and Technology 69 (November 6, 2023): 212–18. http://dx.doi.org/10.54097/hset.v69i.11906.

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Nuclear pollution is a severe environmental problem deriving mainly from industrial activities and can pose extremely negative affect to plants and animal bodies. Nuclear waste also has extreme negative effect on human bodies and can cause various diseases including skin disease, infant deficiency and cancer. There are few studies about the effect of nuclear waste to food webs and how it affects different trophic levels within the ecosystems. This study explains the effect of nuclear pollution on the marine ecosystems and focuses on the transportation of the pollutants through food webs as wel

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Perfilova, O. V., E. B. Khramova, and A. V. Shaitarova. "Potentials of bioimpedance method for nutritional status assessment in children with cerebral palsy." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 66, no. 3 (2021): 40–45. http://dx.doi.org/10.21508/1027-4065-2021-66-3-40-45.

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Objectives: To study the potential of the bioimpedance method for nutritional status assessment in children with cerebral palsy.Material and methods. There were examined 89 children with cerebral palsy (average age: 10,24 years±3,6 years). Such anthropometric indicators as body height (cm), body weight (kg) and body mass index (BMI, kg/m2) were investigated. The scientists formed two comparison groups: Group 1: 40 children without malnutrition (z-score BMI over 1), Group 2: 49 children with malnutrition (z-score BMI is 1,1 and less). The body composition was evaluated by bioimpedancemetry in b

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Guseva, T. S., O. P. Artyukov, M. V. Naprienko, and S. V. Moskvicheva. "Methods of nutritional status assessment in patients with stroke." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 12 (December 20, 2022): 965–73. http://dx.doi.org/10.33920/med-01-2212-05.

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Nutritional deficiency is quite common in patients with acute stroke. Trophic failure correlates with an increased hospital stay, readmissions, and the incidence of developmental complications and mortality. The nutritional deficiency identification is necessary both in the early and in the long-term period of the disease. The clinical review describes the leading diagnostic methods of assessing nutritional status in patients with acute stroke. The comparative characteristics of the applied rating scales and tests are presented. The somatometric, laboratory, and instrumental indicators of maln

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Do Carmo, Sonia, Benjamin Kannel, and A. Claudio Cuello. "The Nerve Growth Factor Metabolic Pathway Dysregulation as Cause of Alzheimer’s Cholinergic Atrophy." Cells 11, no. 1 (2021): 16. http://dx.doi.org/10.3390/cells11010016.

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The cause of the loss of basal forebrain cholinergic neurons (BFCNs) and their terminal synapses in the cerebral cortex and hippocampus in Alzheimer’s disease (AD) has provoked a decades-long controversy. The cholinergic phenotype of this neuronal system, involved in numerous cognitive mechanisms, is tightly dependent on the target-derived nerve growth factor (NGF). Consequently, the loss of BFCNs cholinergic phenotype in AD was initially suspected to be due to an NGF trophic failure. However, in AD there is a normal NGF synthesis and abundance of the NGF precursor (proNGF), therefore the NGF

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Currie, David J. "Phosphorus Deficiency and its Variation among Lakes." Canadian Journal of Fisheries and Aquatic Sciences 47, no. 6 (1990): 1077–84. http://dx.doi.org/10.1139/f90-124.

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The severity of phosphorus deficiency varies greatly among lakes. Is this variation related to particular morphological, chemical, or biological characteristics of lakes? These questions were addressed by sampling 49 lakes in Quebec, Ontario, and the northeastern United States. The rate constant of orthophosphate uptake (k1), a measure of orthophosphate demand:supply, proved to be only weakly related to watershed area and to the total phosphorus (P) concentration of the water (R2 = 0.210). Abundance of the biota and other aspects of water chemistry were all unrelated to the intensity of P-defi

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Terauchi, Aimee M., Graham Peers, Marilyn C. Kobayashi, Krishna K. Niyogi, and Sabeeha S. Merchant. "Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis." Photosynthesis Research 105, no. 1 (2010): 39–49. http://dx.doi.org/10.1007/s11120-010-9562-8.

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10

Cordero-Schmidt, Eugenia, Maricélio Medeiros-Guimarães, Juan Carlos Vargas-Mena, et al. "Are leaves a good option in Caatinga's menu? First record of folivory in Artibeus planirostris (Phyllostomidae) in the semiarid forest, Brazil." Acta Chiropterologica 18, no. 2 (2016): 489–97. https://doi.org/10.5281/zenodo.13458068.

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(Uploaded by Plazi for the Bat Literature Project) Folivory can be defined as the consumption of foliage, including leaves, stems and leaf content. This trophic strategy has been documented in two families of bats, Pteropodidae (Old World fruit bats) and Phyllostomidae (New World leaf-nosed bats). Existing folivory hypotheses for bats suggest this behavior provides a dietary supplement of protein and other essential minerals due to a deficiency of these in a frugivorous diet. The Caatinga is a seasonally deciduous tropical dry forest where most of the vegetation is leafless and dormant during

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Cordero-Schmidt, Eugenia, Maricélio Medeiros-Guimarães, Juan Carlos Vargas-Mena, et al. "Are leaves a good option in Caatinga's menu? First record of folivory in Artibeus planirostris (Phyllostomidae) in the semiarid forest, Brazil." Acta Chiropterologica 18, no. 2 (2016): 489–97. https://doi.org/10.5281/zenodo.13458068.

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(Uploaded by Plazi for the Bat Literature Project) Folivory can be defined as the consumption of foliage, including leaves, stems and leaf content. This trophic strategy has been documented in two families of bats, Pteropodidae (Old World fruit bats) and Phyllostomidae (New World leaf-nosed bats). Existing folivory hypotheses for bats suggest this behavior provides a dietary supplement of protein and other essential minerals due to a deficiency of these in a frugivorous diet. The Caatinga is a seasonally deciduous tropical dry forest where most of the vegetation is leafless and dormant during

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Cordero-Schmidt, Eugenia, Maricélio Medeiros-Guimarães, Juan Carlos Vargas-Mena, et al. "Are leaves a good option in Caatinga's menu? First record of folivory in Artibeus planirostris (Phyllostomidae) in the semiarid forest, Brazil." Acta Chiropterologica 18, no. 2 (2016): 489–97. https://doi.org/10.5281/zenodo.13458068.

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(Uploaded by Plazi for the Bat Literature Project) Folivory can be defined as the consumption of foliage, including leaves, stems and leaf content. This trophic strategy has been documented in two families of bats, Pteropodidae (Old World fruit bats) and Phyllostomidae (New World leaf-nosed bats). Existing folivory hypotheses for bats suggest this behavior provides a dietary supplement of protein and other essential minerals due to a deficiency of these in a frugivorous diet. The Caatinga is a seasonally deciduous tropical dry forest where most of the vegetation is leafless and dormant during

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13

Cordero-Schmidt, Eugenia, Maricélio Medeiros-Guimarães, Juan Carlos Vargas-Mena, et al. "Are leaves a good option in Caatinga's menu? First record of folivory in Artibeus planirostris (Phyllostomidae) in the semiarid forest, Brazil." Acta Chiropterologica 18, no. 2 (2016): 489–97. https://doi.org/10.5281/zenodo.13458068.

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(Uploaded by Plazi for the Bat Literature Project) Folivory can be defined as the consumption of foliage, including leaves, stems and leaf content. This trophic strategy has been documented in two families of bats, Pteropodidae (Old World fruit bats) and Phyllostomidae (New World leaf-nosed bats). Existing folivory hypotheses for bats suggest this behavior provides a dietary supplement of protein and other essential minerals due to a deficiency of these in a frugivorous diet. The Caatinga is a seasonally deciduous tropical dry forest where most of the vegetation is leafless and dormant during

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14

Cordero-Schmidt, Eugenia, Maricélio Medeiros-Guimarães, Juan Carlos Vargas-Mena, et al. "Are leaves a good option in Caatinga's menu? First record of folivory in Artibeus planirostris (Phyllostomidae) in the semiarid forest, Brazil." Acta Chiropterologica 18, no. 2 (2016): 489–97. https://doi.org/10.5281/zenodo.13458068.

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(Uploaded by Plazi for the Bat Literature Project) Folivory can be defined as the consumption of foliage, including leaves, stems and leaf content. This trophic strategy has been documented in two families of bats, Pteropodidae (Old World fruit bats) and Phyllostomidae (New World leaf-nosed bats). Existing folivory hypotheses for bats suggest this behavior provides a dietary supplement of protein and other essential minerals due to a deficiency of these in a frugivorous diet. The Caatinga is a seasonally deciduous tropical dry forest where most of the vegetation is leafless and dormant during

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15

Fossmark, Reidar, Shalini Rao, Patricia Mjønes, et al. "PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa." Peptides 79 (May 2016): 83–94. http://dx.doi.org/10.1016/j.peptides.2016.03.016.

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16

Tsekhomsky, A. V. "Rare case of endocarditis-induced iron deficiency anemia." Clinical Medicine (Russian Journal) 102, no. 9-10 (2025): 767–71. https://doi.org/10.30629/0023-2149-2024-102-9-10-767-771.

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This clinical case highlights the significance of the problem of iron deficiency anemia (IDA) in patients with bacterial endocarditis (BE) and the necessity for a detailed study of the relationships between these diseases.Objective: To investigate the correlation between BE and IDA, as well as to clarify the causal relationships between these conditions. Materials andMethods. The study is based on the examination of a clinical case of a patient with BE and IDA, treated at the Research Institute of Clinical Cardiology No. 1 in Krasnodar, including an analysis of the effectiveness of iron infusi

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Rohrer, Daniel C., Gajanan Nilaver, Valerie Nipper, and Curtis A. Machida. "Genetically Modified Pc 12 Brain Grafts: Survivability and Inducible Nerve Growth Factor Expression." Cell Transplantation 5, no. 1 (1996): 57–68. http://dx.doi.org/10.1177/096368979600500111.

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Neural transplantation of genetically modified cells has been successfully employed to reverse functional deficits in animal models of neurodegenerative disorders, including Parkinson's disease. While implanted PC12 cells secrete dopamine in vivo and can ameliorate dopamine deficiency in parkinsonian rat model systems, these cells either degenerate within 2-3 wk postimplantation (presumably due to the lack of neural trophic factor support at the site of implantation), or in some cases, form a tumor mass leading to the death of the host animal. To address these limitations, we have developed a

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Kim, Min Joung, and Steven Petratos. "Oligodendroglial Lineage Cells in Thyroid Hormone-Deprived Conditions." Stem Cells International 2019 (April 30, 2019): 1–13. http://dx.doi.org/10.1155/2019/5496891.

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Oligodendrocytes are supporting glial cells that ensure the metabolism and homeostasis of neurons with specific synaptic axoglial interactions in the central nervous system. These require key myelinating glial trophic signals important for growth and metabolism. Thyroid hormone (TH) is one such trophic signal that regulates oligodendrocyte maturation, myelination, and oligodendroglial synaptic dynamics via either genomic or nongenomic pathways. The intracellular and extracellular transport of TH is facilitated by a specific transmembrane transporter known as the monocarboxylate transporter 8 (

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19

Richter, Catherine A., Allison N. Evans, Maureen K. Wright-Osment, et al. "Paenibacillus thiaminolyticus is not the cause of thiamine deficiency impeding lake trout (Salvelinus namaycush) recruitment in the Great Lakes." Canadian Journal of Fisheries and Aquatic Sciences 69, no. 6 (2012): 1056–64. http://dx.doi.org/10.1139/f2012-043.

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Thiamine (vitamin B1) deficiency is a global concern affecting wildlife, livestock, and humans. In Great Lakes salmonines, thiamine deficiency causes embryo mortality and is an impediment to restoration of native lake trout ( Salvelinus namaycush ) stocks. Thiamine deficiency in fish may result from a diet of prey with high levels of thiaminase I. The discoveries that the bacterial species Paenibacillus thiaminolyticus produces thiaminase I, is found in viscera of thiaminase-containing prey fish, and causes mortality when fed to lake trout in the laboratory provided circumstantial evidence imp

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HAMILTON, WILLIAM, and MOHSEN M. KHATTAB. "Sex hormone priming prior to the combined hypoglycaemia test." Acta Endocrinologica 113, no. 4_Suppl (1986): S60—S65. http://dx.doi.org/10.1530/acta.0.112s060.

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Abstract The insulin hypoglycaemia test (IHT) was performed on 3 groups of short statured children. One group was unprimed with sex steroid hormones, a second group received 17β-oestradiol, while a third group received testosterone. The dosage of insulin was adjusted to produce a nadir in blood glucose of ⇋ 1 mmol/L. When this level is achieved plasma growth hormone (GH) responses less than 10 mU/L are not improved by either priming procedure. It is suggested from the data that there is no place for a diagnosis of a partial GH deficiency state. When the IHT is combined with Gn-RH and TRH infus

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Kurchenkova, О. V., U. V. Harlamova, A. О. Abdalov, and S. I. Samodurov. "Assessment of the nutritive status in cancer patients of the palliative care department." Ural Medical Journal 20, no. 2 (2021): 80–83. http://dx.doi.org/10.52420/2071-5943-2021-20-2-80-83.

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Introduction. Nutritional status disorders are common among cancer patients. These disorders significantly reduce the quality of life and worsen the prognosis. Objective: to assess the prevalence of trophic insufficiency in palliative care cancer patients.Materials and methods. An observational, analytical, single-stage (crosssectional) study was conducted, which included 106 cancer patients of a palliative profile. The patients underwent laboratory and instrumental examination, a comprehensive assessment of the trophic status. Results. 77 (72.6%) of the examined patients showed signs of nutri

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Perdaens, Océane, and Vincent van Pesch. "Should We Consider Neurodegeneration by Itself or in a Triangulation with Neuroinflammation and Demyelination? The Example of Multiple Sclerosis and Beyond." International Journal of Molecular Sciences 25, no. 23 (2024): 12637. http://dx.doi.org/10.3390/ijms252312637.

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Neurodegeneration is preeminent in many neurological diseases, and still a major burden we fail to manage in patient’s care. Its pathogenesis is complicated, intricate, and far from being completely understood. Taking multiple sclerosis as an example, we propose that neurodegeneration is neither a cause nor a consequence by itself. Mitochondrial dysfunction, leading to energy deficiency and ion imbalance, plays a key role in neurodegeneration, and is partly caused by the oxidative stress generated by microglia and astrocytes. Nodal and paranodal disruption, with or without myelin alteration, i

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Hylander, Samuel, Hanna Farnelid, Emil Fridolfsson, et al. "Thiamin (vitamin B1, thiamine) transfer in the aquatic food web from lower to higher trophic levels." PLOS ONE 19, no. 12 (2024): e0308844. https://doi.org/10.1371/journal.pone.0308844.

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Micronutrients such as vitamins are transferred from lower to higher trophic levels, but no general ecological concept describes the factors regulating this process. Here, we investigated thiamin (thiamine, vitamin B1), which is an example of a metabolically important water-soluble micronutrient. Thiamin is produced by organisms such as bacteria and phytoplankton, and all consumers, such as zooplankton and fish, rely on a continuous intake of thiamin through their diet and possibly from de novo-synthesized thiamin by gut microbiota. A deficiency in thiamin negatively affects reproduction in fi

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Vasiliev, S. A., L. A. Gorgidze, E. E. Efremov, et al. "Fibronectin: structure, functions, clinical significance (review)." Aterotromboz = Atherothrombosis 12, no. 1 (2022): 138–58. http://dx.doi.org/10.21518/2307-1109-2022-12-1-138-158.

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Plasma fibronectin is a high molecular weight adhesive glycoprotein. There are two types of fibronectin: plasma (soluble) and cellular derived (insoluble). Electron microscopy revealed two types of structural organization of fibronectin: compact and expanded. In solution, fibronectin has a compact conformation, and after binding to certain substrates (collagen, fibrin, heparin), it is expanded. Plasma fibronectin is one of the main opsonins of blood plasma in relation to the “targets” of phagocytosis of a predominantly non-bacterial nature, as well as to some types of bacteria. For the treatme

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Cherniak, V. A. "Treatment of trophic ulcers of the lower extremities." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 312–13. http://dx.doi.org/10.32902/2663-0338-2020-3.2-312-313.

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Background. In 50 % of cases trophic ulcers (TU) are caused by chronic venous insufficiency, in 10 % – by arterial insufficiency, in 5 % – by disorders of nerve trophic. Treatment of ischemic TU includes conservative and surgical tactics, wound dressings, pain management, use of hydrogel dressings, antibacterial therapy, measures to improve blood circulation. Objective. To describe the treatment of TU of the lower extremities. Materials and methods. Analysis of literature data on this issue. Results and discussion. The pathogenesis of chronic venous ulcers includes persistent

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Pick, F. R. "Carbohydrate and Protein Content of Lake Seston in Relation to Plankton Nutrient Deficiency." Canadian Journal of Fisheries and Aquatic Sciences 44, no. 12 (1987): 2095–101. http://dx.doi.org/10.1139/f87-259.

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Carbohydrate and protein content of seston from Lake Ontario and Jacks Lake, Ontario, were measured during the ice-free season as a means of estimating plankton nutritional status. Despite the similar trophic level of these lakes, protein to carbohydrate ratios were generally above 1 in Lake Ontario, indicating lack of severe phosphorus or nitrogen deficiency, while those of Jacks Lake were always well below 1, indicating severe nutrient stress. However, in Lake Ontario, some discrepancies with other indicators of nutrient status occurred which complicate interpretations of the ratio. The rati

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POPA, Florina Ligia, Loredana Camelia BOICEAN, Madalina Gabriela ILIESCU, and Mihaela STANCIU. "The importance of association between sexsteroids deficiency, reduction of bone mineral density and falling risk in men with implications in medical rehabilitation." Balneo and PRM Research Journal, Vol.12, no.4 (December 14, 2021): 318–22. http://dx.doi.org/10.12680/balneo.2021.457.

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Introduction. Endocrino-metabolic rehabilitation represent one of the most complex sector in clinical medicine, regarding functional rehabilitation. Sex hormones deficiency plays an important role in the etiology of osteoporosis in men. At the same time, with age, the trophic role of androgens on muscle decreases and determines an increased frequency of falls. The objective of our study is to determine the association between sexsteroids deficiency, reduction of bone mineral density (BMD) and falling risk in men. Methods. Our retrospective cross-sectional study included 146 men aged between 65

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Sandakova, Е. А., and I. G. Zhukovskaya. "Micronutrient deficiency in menstrual dysfunction among women of reproductive age." Perm Medical Journal 38, no. 6 (2021): 59–68. http://dx.doi.org/10.17816/pmj38659-68.

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Objective. To determine whether inorganic menstrual dysfunction (MD) is associated with magnesium, iron and vitamin D deficiency in women of reproductive age. Materials and methods. The study group I consisted of 50 women with MD: dysmenorrhea (16 women), oligomenorrhea (12 women), functional hypothalamic amenorrhea (3 patients) and acyclic abnormal uterine bleeding (19 women), the comparison group II was composed of 30 patients with normal menstrual function. The methods of study included history taking using a questionnaire to detect the signs of magnesium deficiency, physical examinat

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McGuinness, E. E., R. G. H. Morgan, and K. G. Wormsley. "Trophic Effects on the Pancreas of Trypsin and Bile Salt Deficiency in the Small-Intestinal Lumen." Scandinavian Journal of Gastroenterology 20, sup112 (1985): 64–67. http://dx.doi.org/10.3109/00365528509092214.

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Landry, Michael R., Lynnath E. Beckley, and Barbara A. Muhling. "Climate sensitivities and uncertainties in food-web pathways supporting larval bluefin tuna in subtropical oligotrophic oceans." ICES Journal of Marine Science 76, no. 2 (2018): 359–69. http://dx.doi.org/10.1093/icesjms/fsy184.

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Abstract Compared with high-latitude seas, the ecological implications of climate change for top consumers in subtropical regions are poorly understood. One critical area of knowledge deficiency is the nature of food-web connections to larvae during their vulnerable time in the plankton. Bluefin tuna (BFT) are highly migratory temperate species whose early life stages are spent in ultra-oligotrophic subtropical waters. Dietary studies of BFT larvae provide evidence of prey-limited growth coupled with strong selection for specific prey types—cladocerans and poecilostomatoid copepods—whose parad

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ARYSTAN, Leila I., Gulmira M. MULDAEVA, Leila S. HAYDARGALIEVA, Damira K. PAKHOMOVA, and Yernar B. ISKAKOV. "THE STATE OF THE RED BLOOD CELL MEMBRANE IN IRON DEFICIENCY ANAEMIA IN WOMEN OF REPRODUCTIVE AGE." Periódico Tchê Química 16, no. 32 (2019): 471–77. http://dx.doi.org/10.52571/ptq.v16.n32.2019.489_periodico32_pgs_471_477.pdf.

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The problem of iron deficiency is urgent in many countries, regardless of the socio-economic standards of living. Among biomedical problems, the study of biochemical blood parameters is of paramount importance. A great interest in various aspects of this issue is not accidental, since the transport function of the blood largely depends on it and, consequently, the efficient delivery of oxygen, glucose, amino acids, fats, vitamins, mineral salts, hormones, mediators, antibodies and metabolites to the micro-zones in the tissues. The purpose of this article is to study the hematological status an

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Ferrante, Franco, Sergio Blasi, Rolando Crippa, and Francesca Angiero. "Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature." Case Reports in Dentistry 2017 (2017): 1–4. http://dx.doi.org/10.1155/2017/5849173.

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Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved. A deficiency of growth hormone (GH) in children causes the lack of growth known as pituitary dwarfism. The case is reported of a patient with pituitary dwarfism, multiple dental anomalies, functional prosthetic problems, and a revision of the literature. She was subjected to prosthetic rehabilitation without surgical intervention, using zirconium substructures, thus eliminating the potential co

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Noori, Roohollah, Elmira Ansari, Yong-Wook Jeong, et al. "Hyper-Nutrient Enrichment Status in the Sabalan Lake, Iran." Water 13, no. 20 (2021): 2874. http://dx.doi.org/10.3390/w13202874.

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Lakes/reservoirs are rapidly deteriorating from cultural eutrophication due to anthropogenic factors. In this study, we aimed to (1) explore nutrient levels in the Sabalan dam reservoir (SDR) of northwest Iran, (2) determine the reservoir water fertility using the total phosphorus (TP) based and total nitrogen (TN) based Carlson trophic state indices, and (3) specify primary limiting factors for the reservoir eutrophication. Our field observations showed a state of hyper-nutrient enrichment in the SDR. The highest variation of TN in the reservoir water column happened when the reservoir was se

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Bao, Shaowen, Lu Chen, Xiaoxi Qiao, Beat Knusel, and Richard F. Thompson. "Impaired Eye-Blink Conditioning in waggler, a Mutant Mouse With Cerebellar BDNF Deficiency." Learning & Memory 5, no. 4 (1998): 355–64. http://dx.doi.org/10.1101/lm.5.4.355.

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In addition to their trophic functions, neurotrophins are also implicated in synaptic modulation and learning and memory. Although gene knockout techniques have been used widely in studying the roles of neurotrophins at molecular and cellular levels, behavioral studies using neurotrophin knockouts are limited by the early-onset lethality and various sensory deficits associated with the gene knockout mice. In the present study, we found that in a spontaneous mutant mouse, waggler, the expression of brain-derived neurotrophic factor (BDNF) was selectively absent in the cerebellar granule cells.

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Petralla, Sabrina, Luis Emiliano Peña-Altamira, Eleonora Poeta, et al. "Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo." International Journal of Molecular Sciences 20, no. 18 (2019): 4486. http://dx.doi.org/10.3390/ijms20184486.

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Aspartate-Glutamate Carrier 1 (AGC1) deficiency is a rare neurological disease caused by mutations in the solute carrier family 25, member 12 (SLC25A12) gene, encoding for the mitochondrial aspartate-glutamate carrier isoform 1 (AGC1), a component of the malate–aspartate NADH shuttle (MAS), expressed in excitable tissues only. AGC1 deficiency patients are children showing severe hypotonia, arrested psychomotor development, seizures and global hypomyelination. While the effect of AGC1 deficiency in neurons and neuronal function has been deeply studied, little is known about oligodendrocytes and

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Lean, D. R. S., H.-J. Fricker, M. N. Charlton, R. L. Cuhel, and F. R. Pick. "The Lake Ontario Life Support System." Canadian Journal of Fisheries and Aquatic Sciences 44, no. 12 (1987): 2230–40. http://dx.doi.org/10.1139/f87-274.

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Primary productivity provides most of the energy to support aquatic food chains. The rate is not only influenced by available solar radiation but also by temperature, availability of phosphorus, and the influence of physical mixing processes. The special features of Lake Ontario such as changes in phosphorus concentration, calcium carbonate precipitation, and silica deficiency on primary productivity, concentration of particulate carbon, and chlorophyll are discussed. Our lack of understanding of food chain and nutrient regeneration processes is illustrated through our failure to balance carbo

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Macher, Susanne, Cornelia Herster, Magdalena Holter, et al. "The Effect of Parenteral or Oral Iron Supplementation on Fatigue, Sleep, Quality of Life and Restless Legs Syndrome in Iron-Deficient Blood Donors: A Secondary Analysis of the IronWoMan RCT." Nutrients 12, no. 5 (2020): 1313. http://dx.doi.org/10.3390/nu12051313.

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Background: Besides anemia, iron deficiency may cause more subtle symptoms, including the restless legs syndrome (RLS), the chronic fatigue syndrome (CFS) or sleeping disorders. Objective: The aim of this pre-planned secondary analysis of the IronWoMan randomized controlled trial (RCT) was to compare the frequency and severity of symptoms associated with iron deficiency before and after (intravenous or oral) iron supplementation in iron deficient blood donors. Methods/Design: Prospective, randomized, controlled, single-centre trial. (ClinicalTrials.gov: NCT01787526). Setting: Tertiary care cen

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Rabbimova, Dilfuza Toshtemirovna, and Manizha Abdurashidovna Khalilova. "Disorders of energy metabolism, protein and macronutrient metabolism in children with congenital heart defects." Multidisciplinary Journal of Science and Technology 5, no. 4 (2025): 609–13. https://doi.org/10.5281/zenodo.15239146.

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<em>Nutritional deficiency is identified in various types of congenital heart defects, both “blue” and “pale” types. I. Arodiwe et al. [1] in a study of 40,123 children identified 50 with congenital heart defects; 46 (92%) of them had nutritional status changes of varying severity.</em><em> </em><em>According to WHO definition, nutritional deficiency (“nutritional insufficiency”) is a cellular imbalance between the nutrients and energy provided by food and the body’s need for them to ensure vital functions, growth, and specific functions [11, 4].</em>

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Bi, Rong, Stefanie M. H. Ismar-Rebitz, Ulrich Sommer, Hailong Zhang, and Meixun Zhao. "Ocean-related global change alters lipid biomarker production in common marine phytoplankton." Biogeosciences 17, no. 24 (2020): 6287–307. http://dx.doi.org/10.5194/bg-17-6287-2020.

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Abstract. Lipids, in their function as trophic markers in food webs and organic matter source indicators in the water column and sediments, provide a tool for reconstructing the complexity of global change effects on aquatic ecosystems. It remains unclear how ongoing changes in multiple environmental drivers affect the production of key lipid biomarkers in marine phytoplankton. Here, we tested the responses of sterols, alkenones and fatty acids (FAs) in the diatom Phaeodactylum tricornutum, the cryptophyte Rhodomonas sp. and the haptophyte Emiliania huxleyi under a full-factorial combination o

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Loew, Wanitschke, and Schroedter. "Studies on Vitamin B12 Status in the Elderly – Prophylactic and Therapeutic Consequences." International Journal for Vitamin and Nutrition Research 69, no. 3 (1999): 228–33. http://dx.doi.org/10.1024/0300-9831.69.3.228.

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Because of the large liver stores (about 5 mg), low turnover rate (0.143%) and small daily requirement (3 mug), vitamin B12 deficiency does not occur under normal circumstances. This is not the case in individuals with chronic inflammatory or trophic changes at vitamin B12 absorption sites. Without supplementation, vitamin B12 deficiency can be expected within 5 years of gastrectomy. Characteristic features of type A gastritis are hyposecretion and mucosal atrophy in the fundus and body of the stomach, with absent intrinsic factor. In the small intestine, active and/or passive absorption is im

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Simmons, J. G., Y. Ling, H. Wilkins, et al. "Cell-specific effects of insulin receptor substrate-1 deficiency on normal and IGF-I-mediated colon growth." American Journal of Physiology-Gastrointestinal and Liver Physiology 293, no. 5 (2007): G995—G1003. http://dx.doi.org/10.1152/ajpgi.00537.2006.

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Insulin-like growth factor I (IGF-I) potently stimulates intestinal growth. Insulin receptor substrate-1 (IRS-1) mediates proliferative and antiapoptotic actions of IGF-I in cell lines, but its in vivo relevance in intestine is not defined. This study tested the hypothesis that there is cell type-specific dependence on IRS-1 as a mediator of IGF-I action. Length, mass, crypt cell proliferation, and apoptosis were measured in small intestine and colon of IRS-1-null mice and wild-type (WT) littermates and in colon of IRS-1-null or WT mice expressing IGF-I transgenes. Expression of IGF-I receptor

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Frenzel, Anna, Verena Labi, Waldemar Chmelewskij, et al. "Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad." Blood 115, no. 5 (2010): 995–1005. http://dx.doi.org/10.1182/blood-2009-03-212670.

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Abstract Oncogenic c-Myc is known to balance excessive proliferation by apoptosis that can be triggered by p53-dependent and p53-independent signaling networks. Here, we provide evidence that the BH3-only proapoptotic Bcl-2 family members Bcl-2 modifying factor (Bmf) and Bcl-2 antagonist of cell death (Bad) are potent antagonists of c-Myc–driven B-cell lymphomagenesis. Tumor formation was preceded by the accumulation of preneoplastic pre-B and immature immunoglobulin M–positive (IgM+) B cells in hematopoietic organs of Eμ-myc/bmf−/− mice, whereas Eμ-myc/bad−/− mice showed an increase of pre-B

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Yamaguchi, Sayaka, Kiyohito Taira, Kenzo Takahashi, and Hiroshi Uezato. "Langerhans cells are selectively depleted in pellagra skin: the niacin deficiency as immuno-pathogenesis of one more trophic skin disorders." Journal of Dermatological Science 69, no. 2 (2013): e30. http://dx.doi.org/10.1016/j.jdermsci.2012.11.390.

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Ulyanova, L. V., V. S. Ledneva, N. S. Burdina, M. I. Talykova, A. S. Ivannikova, and V. V. Kolomackaya. "Study of the effectiveness of supplementary feeding in patients with inherited enzyme deficiency." Proceedings of the Voronezh State University of Engineering Technologies 81, no. 2 (2019): 239–44. http://dx.doi.org/10.20914/2310-1202-2019-2-239-244.

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The successful provision of optimal nutrition in children with serious diseases depends on the right diet, as well as the addition of specialized mixtures for its correction. The aim of the study was to study the effectiveness of supplemental nutrition in hereditary fermentopathy (cystic fibrosis) in children. The work included a three-year follow-up of 69 children aged 3 to 15 years suffering from cystic fibrosis. Patients were divided into two groups: 37 patients with cystic fibrosis group 1, receiving a modified version of treatment with additional enteral nutrition and 32 patients with cys

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Sirufo, M. M., F. De Pietro, M. Raggiunti, M. De Martinis, and L. Ginaldi. "AB0434 VITAMIN D IN SYSTEMIC SCLEROSIS PATIENTS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1246.1–1246. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2268.

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Background:Systemic Sclerosis (SSc) is a generalized and systemic autoimmune disease that affects the connective tissue of the skin and internal organs, especially kidneys, heart and lungs [1].Objectives:Numerous data from recent literature confirm the regulatory action of vitamin D on the immune system and, therefore, how a deficit of this micronutrient can lead to alterations in the immune response, as is known to happen in many allergic and autoimmune diseases [2]. We studied the association between vitamin D levels and SSc, evaluating their correlation with the characteristic manifestation

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Sherstoboeva, O. V., and O. S. Demianiuk. "TAXONOMIC AND FUNCTIONAL STRUCTURE OF THE MICROBIAL COMMUNITIES OF DARK GREY SOIL." Agriciltural microbiology 24 (October 9, 2016): 43–51. http://dx.doi.org/10.35868/1997-3004.24.43-51.

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We analyzed the functional and taxonomic structure of microbial community of dark grey soil, depending on the effects of the weather and fertilizer systems. It was shown that fallow soil is characterized by integrated and more stable microbial community compared with agroecosystems soil. However, under the effect of such abiotic factors as increased average monthly temperatures and moisture deficiency, some imbalance of trophic interactions in microbiocenosis is observed. Agroecosystems are characterized by less stable functional and taxonomic structure of the soil, which is defined by t

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Sun, Liou Y., M. Steven Evans, Jenny Hsieh, Jacob Panici, and Andrzej Bartke. "Increased Neurogenesis in Dentate Gyrus of Long-Lived Ames Dwarf Mice." Endocrinology 146, no. 3 (2005): 1138–44. http://dx.doi.org/10.1210/en.2004-1115.

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Neurogenesis occurs throughout adult life in the dentate gyrus of mammalian hippocampus and has been suggested to play an important role in cognitive function. Multiple trophic factors including IGF-I have been demonstrated to regulate hippocampal neurogenesis. Ames dwarf mice live considerably longer than normal animals and maintain physiological function at youthful levels, including cognitive function, despite a deficiency of circulating GH and IGF-I. Here we show an increase in numbers of newly generated cells [bromodeoxyuridine (BrdU) positive] and newborn neurons (neuronal nuclear antige

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Hoerterer, Christina, Jessica Petereit, Gisela Lannig, Christian Bock, and Bela Buck. "1H-NMR-Based Metabolic Profiling in Muscle and Liver Tissue of Juvenile Turbot (Scophthalmus maximus) Fed with Plant and Animal Protein Sources." Metabolites 13, no. 5 (2023): 612. http://dx.doi.org/10.3390/metabo13050612.

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Circular economy driven feed ingredients and emerging protein sources, such as insects and microbial meals, has the potential to partially replace fishmeal in diets of high-trophic fish. Even though growth and feed performance are often unaffected at low inclusion levels, the metabolic effects are unknown. This study examined the metabolic response of juvenile turbot (Scophthalmus maximus) to diets with graded fishmeal replacement with plant, animal, and emerging protein sources (PLANT, PAP, and MIX) in comparison to a commercial-like diet (CTRL). A 1H-nuclear magnetic resonance (NMR) spectros

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Zhuravlyova, L. V., and T. A. Rogachova. "Exocrine pancreatic insufficiency in diabetes." Herald of Pancreatic Club 65, no. 4 (2024): 40–45. https://doi.org/10.33149/vkp.2024.04.07.

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One of the underestimated complications of diabetes is exocrine pancreatic insufficiency (EPI). The consequences of EPI in patients with diabetes include malabsorption syndrome and its complications: deficiencies of fat-soluble vitamins A, D, E, and K, osteoporosis, sarcopenia, and increased overall mortality, which emphasizes the importance of early diagnosis and timely treatment of this pathological condition. The prevalence of diabetes is steadily increasing throughout the world, leading to a proportional increase in the prevalence of secondary pancreatic pathology. The aim of this review i

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Le Tissier, Paul R., Danielle F. Carmignac, Sarah Lilley, et al. "Hypothalamic Growth Hormone-Releasing Hormone (GHRH) Deficiency: Targeted Ablation of GHRH Neurons in Mice Using a Viral Ion Channel Transgene." Molecular Endocrinology 19, no. 5 (2005): 1251–62. http://dx.doi.org/10.1210/me.2004-0223.

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Abstract Animal and clinical models of GHRH excess suggest that GHRH provides an important trophic drive to pituitary somatotrophs. We have adopted a novel approach to silence or ablate GHRH neurons, using a modified H37A variant of the influenza virus M2 protein (H37AM2). In mammalian cells, H37AM2 forms a high conductance monovalent cation channel that can be blocked by the antiviral drug rimantadine. Transgenic mice with H37AM2 expression targeted to GHRH neurons developed postweaning dwarfism with hypothalamic GHRH transcripts detectable by RT-PCR but not by in situ hybridization and immun

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