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Journal articles on the topic 'Troxipide'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Dewan, Bhupesh, and Aarthi Balasubramanian. "Troxipide in the Management of Gastritis: A Randomized Comparative Trial in General Practice." Gastroenterology Research and Practice 2010 (2010): 1–7. http://dx.doi.org/10.1155/2010/758397.

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Background. A trial of empirical acid-suppressive therapy is the usual practice for most patients with symptoms of gastritis in primary care.Aim. To assess the relative efficacy of Troxipide and Ranitidine in patients with endoscopic gastritis over a four-week period.Methods. In all, 142 patients were randomized to Troxipide (100 mg tid) or Ranitidine (150 mg bid) for a period of four weeks. The severity of the signs of endoscopic gastritis at baseline and week 4 using a four-point scale and the subjective symptom severity at baseline and week 2 & week 4 using a Visual analog scale (VAS) w

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2

Gowrisankar, D., and N. M. Rao. "DEVELOPMENT AND VALIDATION OF AN IMPROVED STABILITY-INDICATING RP-HPLC METHOD FOR THE ESTIMATION OF TROXIPIDE IN BULK AND TABLET DOSAGE FORMS." INDIAN DRUGS 52, no. 07 (2015): 18–22. http://dx.doi.org/10.53879/id.52.07.10346.

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An improved stability-indicating RP-HPLC method was developed for the estimation of troxipide in bulk and tablet dosage forms. Chromatographic separation of troxipide from its degradation products was achieved on Agilent Zorbax SB-CN (150 × 4.6 mm, 3.5 μm) using sodium phosphate buffer (pH was adjusted to 4.0 ±0.05) and acetonitrile in the ratio of 40:60 V/V, at a flow rate of 0.8 mL/min. This system was found to give compact peak for troxipide at 2.1±0.2 min. The detection was monitored at 260 nm. The linear regression data for the calibration plots showed good relationship with r2 = 0.99 ± 0

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3

Jagdale, Swati C., Shraddha B. Kamble, Bhanudas S. Kuchekar, and Aniruddha R. Chabukswar. "Design and Evaluation of Polyox and Pluronic Controlled Gastroretentive Delivery of Troxipide." Journal of Drug Delivery 2014 (November 19, 2014): 1–10. http://dx.doi.org/10.1155/2014/804616.

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Objective. Objective of the present work was to develop site-specific gastroretentive drug delivery of Troxipide using polymers Pluronic F127 and Polyox 205 WSR. Troxipide is a novel gastroprotective agent with antiulcer, anti-inflammatory, and mucus secreting properties with elimination half-life of 7.4 hrs. Troxipide inhibits H. pylori-derived urease. It is mainly absorbed from stomach. Methods. 32 factorial design was applied to study the effect of independent variable. Effects of concentration of polymer on dependant variables as swelling index, hardness, and % drug release were studied. P

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4

&NA;. "Troxipide with an H2 antagonist heals gastric ulcers." Inpharma Weekly &NA;, no. 761 (1990): 9. http://dx.doi.org/10.2165/00128413-199007610-00022.

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5

Akilandeswari, Krishnan, and Kandasamy Ruckmani. "Antibacterial potentiality of antiulcer and antispasmodic drugs with selected antibiotics against methicillin resistant Staphylococcus aureus: In vitro and in silico studies." Bangladesh Journal of Pharmacology 10, no. 4 (2015): 875. http://dx.doi.org/10.3329/bjp.v10i4.25271.

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<p class="Abstract">In the present study, the antispasmodic drug mebeverine hydrochloride and the antiulcer drug troxipide were tested for their possible antibacterial properties <em>in vitro</em>. The antimicrobial assays of the above drugs were determined with ampicillin, penicillin and ciprofloxacin against sensitive and resistant strains and their resistance were confirmed through Polymerase Chain Reaction by identifying the presence of the <em>mec</em>A gene. A computer-aided method was used for screening the effectiveness of the drug interactions. Mebeverine

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6

Karpe, Manisha, Monika Kumbhar, Ravindra Tupe, Gaurav Bhamare, and Vilasrao Kadam. "Formulation, Optimization and Characterization of Gastro-rententive Troxipide Microspheres." International Journal of Pharmaceutical Chemistry and Analysis 3, no. 3 (2016): 133. http://dx.doi.org/10.5958/2394-2797.2016.00020.4.

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7

SEKIGUCHI, Haruo, Katsuhiro HAMADA, Yumiko OKADA, and Fukutaro TAGA. "Effects of troxipide on acute gastric lesions in rats." Folia Pharmacologica Japonica 89, no. 3 (1987): 111–19. http://dx.doi.org/10.1254/fpj.89.111.

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8

Lu, Nan, Jin-ling Huo, Shuai Wang, Xiao-Han Yuan, and Hong-Min Liu. "Drug repurposing: Discovery of troxipide analogs as potent antitumor agents." European Journal of Medicinal Chemistry 202 (September 2020): 112471. http://dx.doi.org/10.1016/j.ejmech.2020.112471.

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9

Jagdale, Swati, Shraddha B. Kamble, Bhanudas S. Kuchekar, and Aniruddha R. Chabukswar. "Development and Optimization of Troxipide Floating Delivery for Treatment of Peptic Ulcer." Current Drug Therapy 9, no. 2 (2014): 83–92. http://dx.doi.org/10.2174/1574885508666131217003926.

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10

Gao, Yunyun, Yang Gao, Fei Yin, et al. "Preparation and pharmacokinetics study on gastro-floating sustained-release tablets of troxipide." Drug Development and Industrial Pharmacy 41, no. 9 (2014): 1443–51. http://dx.doi.org/10.3109/03639045.2014.956113.

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11

Kadowaki, Reita, Fumihiko Ogata, Miku Nishida, et al. "Therapeutic Effects of Hydrogel Formulations Incorporating Troxipide Nanoparticles on Oral Mucositis in Hamsters." Drug Design, Development and Therapy Volume 17 (November 2023): 3349–61. http://dx.doi.org/10.2147/dddt.s433776.

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12

Cooper, Elizabeth, Peter J. Choi, Patrick Schweder, et al. "Cytoprotective agent troxipide-cyanine dye conjugate with cytotoxic and antiproliferative activity in patient-derived glioblastoma cell lines." Bioorganic & Medicinal Chemistry Letters 50 (October 2021): 128336. http://dx.doi.org/10.1016/j.bmcl.2021.128336.

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13

Watanabe, Kazuhiro, Shinya Nagamatsu, Satoshi Hoshiya, et al. "The effect of a novel gastric mucosal protective agent, troxipide, on Helicobacter pylori induced gastric cellular apoptosis." Gastroenterology 118, no. 4 (2000): A1321. http://dx.doi.org/10.1016/s0016-5085(00)81146-4.

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14

Kusugami, K. "Troxipide, a novel antiulcer compound, has inhibitory effects on human neutrophil migration and activation induced by various stimulants." Digestive and Liver Disease 32, no. 4 (2000): 305–11. http://dx.doi.org/10.1016/s1590-8658(00)80023-7.

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15

Krishnan, Akilandeswari, and Ruckmani Kandasamy. "NONANTIBIOTICS ENHANCE THE ANTIBACTERIAL ACTIVITY OF CEFTRIAXONE AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 134. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.21535.

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Objectives: Antibiotic resistance is one of the most persistent issues worldwide nowadays, and methicillin-resistant Staphylococcus aureus (MRSA) infection is one such issue where the standard therapeutic procedures involving powerful antibiotics have failed in controlling the infection.Methods: In the present study, the antibacterial potency of the nonantibiotics troxipide (TR), mebeverine hydrochloride (Hcl), and their combinations with ceftriaxone (CEF) against MRSA has been investigated using microbiological assays of microplate dilution method and combination index interpretations of the

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16

MOMO, Kenjiro, Kohei HOSHINA, Yuji ISHIBASHI, and Takao SAITO. "Preventive effects of troxipide on a newly developed model of acute gastric mucosal lesion(AGML) induced by ischemia/reperfusion plus ammonia in the rat." Folia Pharmacologica Japonica 104, no. 4 (1994): 313–23. http://dx.doi.org/10.1254/fpj.104.313.

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17

Dewan, Bhupesh. "An Open-Label, Multicenter Post Marketing Study to Assess the Symptomatic Efficacy and Safety of Troxipide [TroxipTM] in the Management of Acid Peptic Disorders in Indian Patients." British Journal of Medicine and Medical Research 3, no. 4 (2013): 1881–92. http://dx.doi.org/10.9734/bjmmr/2013/4310.

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18

Dewan, Bhupesh, and Deepashri Shah. "An Open-Label, Multicenter Post Marketing Study to Assess the Symptomatic Efficacy and Safety of Troxipide [TroxipTM] in the Management of Acid Peptic Disorders in Indian Patients." June 16, 2013. https://doi.org/10.5281/zenodo.8025.

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Aims: A post marketing study to assess the symptomatic efficacy and safety of Troxipide (TROXIPTM) 100mg in the management of acid peptic disorders (APDs) in Indian population. Study Design: An observational, prospective, uncontrolled, open-label, multicenter post marketing study. Place and Duration of Study: Patients were enrolled from 62 centers across 11 states of India, between October 2010 and March 2012. Methodology: Out of 1500 APD patients, 1486 (850 men, 636 women; age range 16-85 years) were prescribed Troxipide 100mg tablet orally thrice daily. The efficacy and safety assessments we

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19

Sahu Navajit, Dewan Bhupesh. "Bioequivalence Study of Troxipide Tablet Formulations." Journal of Bioequivalence & Bioavailability 02, no. 02 (2010). http://dx.doi.org/10.4172/jbb.1000030.

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20

Guo, Hongbin, Baohua Chen, Zihan Yan, Jian Gao, Jiamei Tang, and Chengyan Zhou. "Metabolites profiling and pharmacokinetics of troxipide and its pharmacodynamics in rats with gastric ulcer." Scientific Reports 10, no. 1 (2020). http://dx.doi.org/10.1038/s41598-020-70312-7.

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21

Nazela Constantia Hilyatul Aulia, Sani Ega Priani, and Ratih Aryani. "Kajian Pengembangan Sediaan Floating Sustained Release Tablet." Bandung Conference Series: Pharmacy 2, no. 2 (2022). http://dx.doi.org/10.29313/bcsp.v2i2.3122.

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Abstract. Floating sustained release tablets were developed to increase the elimination half-life and bioavailability of the drug because it is able to release the active substance for a long duration by a floating mechanism in gastric fluid. This study aims to examine the development of floating tablets for the purpose of sustained release in terms of formulation and manufacturing methods, as well as the effect of developing floating sustained release tablets on pharmacokinetic parameters. The research method used is a systematic literature review by searching for international articles from

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22

Xu, Yuanyuan, Yuan Gao, Zhong Chen, et al. "Metabolomics analysis of the soapberry (Sapindus mukorossi Gaertn.) pericarp during fruit development and ripening based on UHPLC-HRMS." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-91143-0.

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AbstractSoapberry (Sapindus mukorossi Gaertn.) is a multi-functional tree with widespread application in toiletries, biomedicine, biomass energy, and landscaping. The pericarp of soapberry can be used as a medicine or detergent. However, there is currently no systematic study on the chemical constituents of soapberry pericarp during fruit development and ripening, and the dynamic changes in these constituents still unclear. In this study, a non-targeted metabolomics approach using ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) was used to comprehens

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