Academic literature on the topic 'TRPV1'

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Journal articles on the topic "TRPV1"

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Sharma, Deep, Rekha Rana, and Kiran Thakur. "A REVIEW ON ROLE OF TRPV CATION CHANNELS." Journal of Biomedical and Pharmaceutical Research 10, no. 2 (2021): 32–51. http://dx.doi.org/10.32553/jbpr.v10i2.857.

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The mammalian branch of the Transient Receptor Potential (TRP) superfamily of cation channels consists of 28 members. They can be subdivided in six main subfamilies: the TRPC (‘Canonical’), TRPV (‘Vanilloid’), TRPM (‘Melastatin’), TRPP (‘Polycystin’), TRPML (‘Mucolipin’) and the TRPA (‘Ankyrin’) group. The TRPV subfamily comprises channels that are critically involved in nociception and thermo-sensing (TRPV1, TRPV2, TRPV3, TRPV4) as well as highly Ca2+ selective channels involved in Ca2+ absorption/ reabsorption in mammals (TRPV5, TRPV6). In this review we summarize fundamental physiological p
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Chung, Gehoon, and Seog Bae Oh. "TRP Channels in Dental Pain." Open Pain Journal 6, no. 1 (2013): 31–36. http://dx.doi.org/10.2174/1876386301306010031.

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Despite the high incidence of dental pain, the mechanism underlying its generation is mostly unknown. Functional expression of temperature-sensitive transient receptor potential (thermo-TRP) channels, such as TRPV1, TRPV2, TRPM8, and TRPA1 in dental primary afferent neurons and TRPV1, TRPV2, TRPV3, TRPV4, and TRPM3 in odontoblasts, has been demonstrated and suggested as responsible for dental pain elicited by hot and cold food. However, dental pain induced by light touch or sweet substance cannot be explained by the role of thermo-TRP channels. Most of current therapeutics of dentin hypersensi
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Marshall-Gradisnik, Sonya M., Peter Smith, Ekua W. Brenu, Bernd Nilius, Sandra B. Ramos, and Donald R. Staines. "Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients." Immunology and Immunogenetics Insights 7 (January 2015): III.S25147. http://dx.doi.org/10.4137/iii.s25147.

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Background The transient receptor potential (TRP) superfamily in humans comprises 27 cation channels with permeability to monovalent and divalent cations. These channels are widely expressed within humans on cells and tissues and have significant sensory and regulatory roles on most physiological functions. Chronic fatigue syndrome (CFS) is an unexplained disorder with multiple physiological impairments. OBJECTIVES The purpose of this study was to determine the role of TRPs in CFS. Methods The study comprised 115 CFS patients (age = 48.68 ± 1.06 years) and 90 nonfatigued controls (age = 46.48
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Toledo Mauriño, Joel J., Gabriela Fonseca-Camarillo, Janette Furuzawa-Carballeda, et al. "TRPV Subfamily (TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6) Gene and Protein Expression in Patients with Ulcerative Colitis." Journal of Immunology Research 2020 (May 8, 2020): 1–11. http://dx.doi.org/10.1155/2020/2906845.

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Introduction. TRPVs are a group of receptors with a channel activity predominantly permeable to Ca2+. This subfamily is involved in the development of gastrointestinal diseases such as ulcerative colitis (UC). The aim of the study was to characterize the gene and protein expression of the TRPV subfamily in UC patients and controls. Methods. We determined by quantitative PCR the gene expression of TRPV2, TRPV3, TRPV4, TRPV5, and TRPV6 in 45 UC patients (29 active UC and 16 remission UC) and 26 noninflamed controls. Protein expression was evaluated in 5 μm thick sections of formalin-fixed, paraf
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Kotova, O. O. "Modern concepts of the role of transient receptor potential channel vanilloid subfamily (TRPV) in development osmotic airway hyperresponsiveness in asthma patients (review)." Bulletin Physiology and Pathology of Respiration, no. 81 (September 29, 2021): 115–25. http://dx.doi.org/10.36604/1998-5029-2021-81-115-125.

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Introduction. Airway hyperresponsiveness to osmotic stimuli is often found among patients with asthma. It is assumed that the transient receptor potential channels of vanilloid subfamily (TRPV) may play a key role in the onset of this phenomenon.Aim. Review of modern world literature data on osmotic airway hyperresponsiveness and the role of TRPV channels in its development.Materials and methods. This review summarizes the data from articles published over the past five years found in PubMed and Google Scholar. However, earlier publications were also included if necessary.Results. The influenc
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Yang, Xiao-Ru, Mo-Jun Lin, Lionel S. McIntosh, and James S. K. Sham. "Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle." American Journal of Physiology-Lung Cellular and Molecular Physiology 290, no. 6 (2006): L1267—L1276. http://dx.doi.org/10.1152/ajplung.00515.2005.

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Transient receptor potential melastatin- (TRPM) and vanilloid-related (TRPV) channels are nonselective cation channels pertinent to diverse physiological functions. Multiple TRPM and TRPV channel subtypes have been identified and cloned in different tissues. However, their information in vascular tissue is scant. In this study, we sought to identify TRPM and TRPV channel subtypes expressed in rat deendothelialized intralobar pulmonary arteries (PAs) and aorta. With RT-PCR, mRNA of TRPM2, TRPM3, TRPM4, TRPM7, and TRPM8 of TRPM family and TRPV1, TRPV2, TRPV3, and TRPV4 of TRPV family were detect
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Keller, Melina, Stefan Mergler, Aruna Li, Ingrid Zahn, Friedrich Paulsen, and Fabian Garreis. "Thermosensitive TRP Channels Are Functionally Expressed and Influence the Lipogenesis in Human Meibomian Gland Cells." International Journal of Molecular Sciences 25, no. 7 (2024): 4043. http://dx.doi.org/10.3390/ijms25074043.

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While the involvement of thermosensitive transient receptor potential channels (TRPs) in dry eye disease (DED) has been known for years, their expression in the meibomian gland (MG) has never been investigated. This study aims to show their expression and involvement in the lipogenesis of the MG, providing a possible new drug target in the treatment of DED. Our RT-PCR, Western blot and immunofluorescence analysis showed the expression of TRPV1, TRPV3, TRPV4 and TRPM8 in the MG at the gene and the protein level. RT-PCR also showed gene expression of TRPV2 but not TRPA1. Calcium imaging and plan
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Zhang, Lei, Sarahlouise Jones, Kate Brody, Marcello Costa, and Simon J. H. Brookes. "Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse." American Journal of Physiology-Gastrointestinal and Liver Physiology 286, no. 6 (2004): G983—G991. http://dx.doi.org/10.1152/ajpgi.00441.2003.

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A number of transient receptor potential (TRP) channels has recently been shown to mediate cutaneous thermosensitivity. Sensitivity to warm and cool stimuli has been demonstrated in both human and animal gastrointestinal tract; however, the molecular mechanisms that underlie this have not been determined. Vagal afferent neurons with cell bodies in the nodose ganglion are known to mediate nonnociceptive sensation from the upper gut. In this study, isolated cultured nodose ganglion from the mouse neurons showed changes in cytoplasmic-free Ca2+concentrations over a range of temperatures, as well
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Peng, Gongyong, Wenju Lu, Xiaoyan Li, et al. "Expression of store-operated Ca2+ entry and transient receptor potential canonical and vanilloid-related proteins in rat distal pulmonary venous smooth muscle." American Journal of Physiology-Lung Cellular and Molecular Physiology 299, no. 5 (2010): L621—L630. http://dx.doi.org/10.1152/ajplung.00176.2009.

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Chronic hypoxia causes remodeling and alters contractile responses in both pulmonary arteries and pulmonary veins. Although pulmonary arteries have been studied extensively in these disorders, the mechanisms by which pulmonary veins respond to hypoxia and whether these responses contribute to chronic hypoxic pulmonary hypertension remain poorly understood. In pulmonary arterial smooth muscle, we have previously demonstrated that influx of Ca2+ through store-operated calcium channels (SOCC) thought to be composed of transient receptor potential (TRP) proteins is likely to play an important role
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Kuwashima, Yutaro, Masataka Yanagawa, Mitsuhiro Abe, et al. "Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells." International Journal of Molecular Sciences 22, no. 16 (2021): 8473. http://dx.doi.org/10.3390/ijms22168473.

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TRPV1 and TRPV4, members of the transient receptor potential vanilloid family, are multimodal ion channels activated by various stimuli, including temperature and chemicals. It has been demonstrated that TRPV channels function as tetramers; however, the dynamics of the diffusion, oligomerization, and endocytosis of these channels in living cells are unclear. Here we undertook single-molecule time-lapse imaging of TRPV1 and TRPV4 in HEK 293 cells. Differences were observed between TRPV1 and TRPV4 before and after agonist stimulation. In the resting state, TRPV4 was more likely to form higher-or
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Dissertations / Theses on the topic "TRPV1"

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Hering, Nils [Verfasser]. "Elektrophysiologische Charakterisierung der Ionenkanäle TRPV1, TRPV3 und TRPV4 exprimiert in Xenopus Oozyten. / Nils Hering." Kiel : Universitätsbibliothek Kiel, 2016. http://d-nb.info/1096220881/34.

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Hasan, S. M. Raquibul. "Modulation of the TRPA1 and TRPV1 ion channels." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708079.

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Hellwig, Nicole. "Protonenleitfähigkeit von TRPV1 und Multimerisierung von TRPV-Kanaluntereinheiten." [S.l.] : [s.n.], 2005. http://www.diss.fu-berlin.de/2005/177/index.html.

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Sinha, Sayantani. "Role of TRPA1 and TRPV1 in Propofol Induced Vasodilation." Thesis, Kent State University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3618926.

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<p> <b>Aims:</b> Propofol, clinically named as Diprivan is an intravenous anesthetic known to cause hypotension in patients presenting for surgery. We have investigated the vasodilatory signaling cascade by which propofol causes hypotension using both <i>in vivo</i> and <i>in vitro </i> experimental approaches. </p><p> <b>Methods and Results:</b> Using high-fidelity microtip transducer catheter, mean arterial blood pressure (MAP) was measured in control, transient receptor potential ankyrin subtype 1 knock-out (TRPA1<sup>-/-</sup>), transient receptor potential vanilloid 1 knock-out (TRPV1<s
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SINHA, SAYANTANI. "Role of TRPA1 and TRPV1 in Propofol Induced Vasodilation." Kent State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=kent1384901930.

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Sprague, Jared Michael. "TRPV1 Sensitization in Primary Sensory Neurons." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11441.

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Pain is a major personal and community burden throughout the world with currently limited treatment options for persistent pain due to unacceptable side effects, dependence or frank inefficacy. It is necessary to understand the anatomical and molecular pathways leading to pain to better cope with the current challenge of treating it.
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O'Leary, Caitriona. "The role of TRPV1 and TRPV4 channels in retinal angiogenesis." Thesis, Queen's University Belfast, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709849.

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Abnormal angiogenesis is a key pathological process associated with many diseases such as metastatic cancer, atherosclerosis, and sight-threatening disorders including proliferative diabetic retinopathy, neovascular age-related macular degeneration, and retinopathy of prematurity. Calcium signalling is fundamental for many endothelial functions including the regulation of blood vessel tone, barrier selectivity and angiogenesis. Calcium influx has been implicated in retinal endothelial cell angiogenic response, but the molecular identity of the underlying calcium channels remains to be fully el
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Sinharoy, Pritam. "Cross Talk Between TRPA1 and TRPV1 Ion-Channels: Role of Nitric Oxide." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1467381679.

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Chen, Lan [Verfasser]. "Functional TRPV1 and TRPV4 channels in the murine renal vasculature / Lan Chen." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1148425926/34.

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SUGIHARA, YASUO, MINORU UEDA, HIDEYUKI NAKASHIMA, et al. "INVOLVEMENT OF GLIAL ACTIVATION IN TRIGEMINAL GANGLION IN A RAT MODEL OF LOWER GINGIVAL CANCER PAIN." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/20551.

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Books on the topic "TRPV1"

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Gomtsyan, Arthur, and Connie R. Faltynek, eds. Vanilloid Receptor TRPV1 in Drug Discovery. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470588284.

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Malmberg, Annika B., and Keith R. Bley, eds. Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7379-2.

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Gomtsyan, Arthur. Vanilloid receptor TRPV1 in drug discovery: Targeting pain and other pathological disorders. Wiley, 2010.

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Gomtsyan, Arthur. Vanilloid receptor TRPV1 in drug discovery: Targeting pain and other pathological disorders. Wiley, 2010.

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McGoldrick, Luke Lawrence Reedy. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6. [publisher not identified], 2019.

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1966-, Malmberg Annika B., and Bley Keith R, eds. Turning up the heat on pain: TRPVI receptors in pain and inflammation. Birkhauser Verlag, 2005.

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Doyle, Christina. Functional Characterization of the Mammalian TRPV4 Channel: Yeast Screen Reveals Gain-of-Function Mutations. [publisher not identified], 2012.

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Liu, Shu. Temperature- and touch-sensitive neurons couple CNG and TRPV channel activities to control heat avoidance in Caenorhabditis elegans. Universität, 2012.

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Gomtsyan, Arthur, and Connie R. Faltynek. Vanilloid Receptor Trpv1 in Drug Discovery. Wiley & Sons, Incorporated, John, 2010.

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Sprague, Jared Michael. TRPV1 Sensitization in Primary Sensory Neurons. 2014.

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Book chapters on the topic "TRPV1"

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Zhu, Michael X. "Transient Receptor Potential Channels TRPV1, TRPV2, and TRPV3." In Encyclopedia of Metalloproteins. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-1533-6_441.

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Bevan, Stuart, Talisia Quallo, and David A. Andersson. "TRPV1." In Handbook of Experimental Pharmacology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54215-2_9.

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Winter, Janet. "TRPV1 distribution and regulation." In Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7379-2_3.

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Belvisi, Maria G., and Peter J. Barnes. "TRPV1 in the airways." In Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7379-2_9.

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McNaughton, Peter A. "TRPV1 Modulation by PKC." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_4645.

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McIntyre, Peter. "TRPV1 Receptor, Species Variability." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_4650.

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Jordt, Sven-Eric. "TRPV1, Regulation by Protons." In Encyclopedia of Pain. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-28753-4_4653.

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Valenzano, Kenneth J., James D. Pomonis, and Katharine Walker. "TRPV1 antagonists and chronic pain." In Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7379-2_12.

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Tominaga, Makoto. "Structural determinants of TRPV1 functionality." In Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation. Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/3-7643-7379-2_2.

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Moriello, Aniello Schiano, and Luciano De Petrocellis. "Assay of TRPV1 Receptor Signaling." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3539-0_7.

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Conference papers on the topic "TRPV1"

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Grace, Megan S., Mark A. Birrell, Sarah A. Maher, and Maria G. Belvisi. "TRPA1 And TRPV1 Mediate Tussive Responses To PGE2, Bradykinin And Low PH." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5543.

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Szőke, Éva, Andrea Nehr-Majoros, Ádám Horváth, et al. "Cyclodextrins decrease TRPV1 and TRPA1 ion channel activation via lipid raft disruption." In ASPET 2023 Annual Meeting Abstracts. American Society for Pharmacology and Experimental Therapeutics, 2023. http://dx.doi.org/10.1124/jpet.122.168550.

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Maher, Sarah A., Megan S. Grace, Mark A. Birrell, and Maria G. Belvisi. "Prostaglandin E2-Induced Sensory Nerve Activation Is Mediated By TRPA1 And TRPV1." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5541.

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Li, F., and M. Wang. "The Role of TRPA1/TRPV1 in PM2.5 -Induced Airway Epithelial Cell Injury Model." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7224.

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Hazari, MS, N. Haykal-Coates, DW Winsett, AK Farraj, and DL Costa. "Acrolein Causes TRPA1-Mediated Sensory Irritation and Indirect Potentiation of TRPV1-Mediated Pulmonary Chemoreflex Response." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a3152.

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Kotova, Olesya, Denis Naumov, Anna Prikhodko, Juliy Perelman, and Victor Kolosov. "TRPV1 and TRPV2 are up-regulated in the airways of asthma patients with osmotic airway hyperresponsiveness." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa1820.

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Sahebari, M., SZ Mirfeizi, and J. Salimi. "PS1:14 Trpv1 receptor activity in lupus." In 11th European Lupus Meeting, Düsseldorf, Germany, 21–24 March 2018, Abstract presentations. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-abstract.62.

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Suh, Eul, Agnella Izzo Matic, Margarete Otting, Joseph T. Walsh, Jr., and Claus-Peter Richter. "Optical stimulation in mice lacking the TRPV1 channel." In SPIE BiOS: Biomedical Optics, edited by Anita Mahadevan-Jansen and E. Duco Jansen. SPIE, 2009. http://dx.doi.org/10.1117/12.816891.

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Duarte, AG, GA Campbell, and AC Myers. "Quantitative Assessment of TRPV1 in Lung Transplant Recipients." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a6052.

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Jendzjowsky, N., A. Roy, and R. Wilson. "Th2 Cytokines Stimulate Carotid Body Chemoreceptors via TRPV1 Channels." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5603.

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Reports on the topic "TRPV1"

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Mohapatra, Durga P., Andrew Shepherd, and Lipin Loo. Therapeutic Targeting of TRPV1 for the Treatment of Chronic Pain Associated with Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada612310.

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Mohapatra, Durga P., Betty Diamond, Lipin Loo, and Andrew Shepherd. Therapeutic Targeting of TRPV1 for the Treatment of Chronic Pain Associated with Prostate Cancer Bone Metastasis. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada566497.

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Zuraw, Bruce L. Epithelial Cell TRPV1-Mediated Airway Sensitivity as a Mechanism for Respiratory Symptoms Associated with Gulf War Illness?". Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada536752.

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Buys, Michael J. Use of the TRPV1 Agonist Capsaicin to Provide Long-Term Analgesia in a Rat Limb Fracture/Open Repair, Internal Fixation Model. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada569521.

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Buys, Michael J. Use of the TRPV1 Agonist Capsaicin to Provide Long-Term Analgesia in a Rat Limb Fracture/Open Repair, Internal Fixation Model. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada569523.

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Li, Jiawang, Xiangyun Chen, Hongrui Zhang, et al. A Systematic Review of the Capsaicin and other TRPV1 agonists effects on three neurodegenerative diseases: Alzheimer's disease, Parkinson's disease and Ischemic Stroke. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.4.0115.

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