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1

Wooley, Charles F. "Florence Rena Sabin (1871–1953), William Osler (1849–1919) and Tuberculosis." Journal of Medical Biography 13, no. 3 (2005): 162–69. http://dx.doi.org/10.1177/096777200501300311.

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Florence Rena Sabin received her MD from the Johns Hopkins University in 1900. She was one of the first women to become a medical intern at Johns Hopkins and worked for the year of her internship (1900–01) under William Osler. At Johns Hopkins from y>1902 to 1925, Sabin studied embryology and histology with mentor Franklin Mall. She became the first woman professor of histology at an American school. Recruited to the Rockefeller Institute (1925), she focused on tuberculosis immunology, tubercle-bacillus biochemistry and haematology. She was the first woman department head at the Rockefeller
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2

Hamada, Hiromasa, Maria de la Luz Garcia-Hernandez, Joyce B. Reome, Sara K. Misra, and Richard W. Dutton. "The mechanism of protection against influenza by transfer of Tc17, an IL-17 secreting CD8 T cell subset. (46.5)." Journal of Immunology 182, no. 1_Supplement (2009): 46.5. http://dx.doi.org/10.4049/jimmunol.182.supp.46.5.

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Abstract Interleukin (IL) -17 secreting CD4 T (Th)17 and CD8 T (Tc)17 effector cells are found in the lung following primary challenge with influenza A and blocking antibody to IL-17 increases weight loss and reduces survival. Tc17 effectors can be generated in vitro using naïve CD8 T cells from OT-1 T cell receptor (TcR) transgenic mice. T cell numbers expand 20 fold and a majority secretes IL-17, but little IFN-γ. Tc17 effectors are negative for granzyme B, for perforin message and lack cytolytic activity in vitro, in contrast to Tc1 effectors. Many of the Tc17 effectors become IFN-γ/IL-17
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Tsukamoto, Hirotake, Karen Clise-Dwyer, Gail E. Huston, et al. "The Lifespan of Naïve CD4 T cells is a Critical Determinant for the Cellular Aging in Periphery (46.2)." Journal of Immunology 182, no. 1_Supplement (2009): 46.2. http://dx.doi.org/10.4049/jimmunol.182.supp.46.2.

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Abstract Cell intrinsic functional defect in aged naive CD4 T cells is a key cause of an age-associated increase in susceptibility to infectious diseases. However the causes of the CD4 T cell defects and how they develop are largely unknown. We have suggested that many defects develop during the sojourn of the naïve CD4 T cells in the periphery. We report here that aged naïve CD4 T cells have a longer lifespan than young cells even when transferred to young intact hosts. In vitro studies suggest that their increased longevity is regulated by an intrinsic property for survival. Consistent wit
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4

Kohlmeier, Jacob E., Shannon C. Miller, Tres Cookenham, Alan D. Roberts, and David L. Woodland. "Type I interferon-dependent regulation of granzyme B protein expression by memory CD8+ T cells during the early stages of a respiratory virus challenge (130.13)." Journal of Immunology 182, no. 1_Supplement (2009): 130.13. http://dx.doi.org/10.4049/jimmunol.182.supp.130.13.

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Abstract Memory T cells established following the resolution of influenza and parainfluenza virus infections provide robust protection from a secondary virus challenge. Recently, we demonstrated that the rapid recruitment of circulating memory CD8+ T cells to the lung airways during the early stages of a secondary challenge is crucial for limiting early viral replication. In the course of these studies, we observed that the cytolytic protein granzyme B (gzmB) was highly expressed by virus-specific memory CD8+ T cells recruited to the lung airways. However, the mechanism by which gzmB protein i
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Jelley-Gibbs, Dawn M., K. Kai McKinstry, John P. Dibble, Alan D. Roberts, David L. Woodland, and Susan L. Swain. "CD4 memory T cells regulate mediators of lung damage during respiratory infections (130.8)." Journal of Immunology 182, no. 1_Supplement (2009): 130.8. http://dx.doi.org/10.4049/jimmunol.182.supp.130.8.

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Abstract Activated T cells play a central role in controlling respiratory virus infections. However, these T cells also mediate considerable pulmonary immunopathology and lung damage. The level of immunopathology tends to be much less in secondary compared to primary infections, but the underlying reasons for this difference are unclear. To determine if CD4 memory T cells regulate pulmonary immunopathology, we transferred influenza-specific CD4 memory T cells into naïve mice challenged with influenza virus and assessed (i) inflammation, (ii) antigen presentation, and (iii) de novo T cell stim
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Brown, Deborah M., and Anna T. Lampe. "Combined CpG and MPL as vaccine adjuvants improve immunity and heterosubtypic protection against lethal viral challenge in single dose and prime/boost regimens." Journal of Immunology 208, no. 1_Supplement (2022): 64.19. http://dx.doi.org/10.4049/jimmunol.208.supp.64.19.

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Abstract Current Influenza A virus (IAV) vaccines show poor efficacy, often 40–60%. A strategy to improve effectiveness of IAV vaccines is to include adjuvants to activate innate immunity. We examined the potential of combined pattern recognition receptor agonists CpG and MPL to increase IAV vaccine induced protection. When administered in a single, low dose intramuscular hemagglutinin (HA) protein vaccine, mice receiving MPL + CpG experienced less morbidity after homologous challenge compared to mice receiving single agonists. In experiments analyzing heterosubtypic protection, vaccines conta
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Brown, Deborah M., Jenna Briere, Hoi Lam Cheang, Dylan Custer, William C. Reiley, and Ethan Laferriere. "Combination adjuvants and antigens provide heterosubtypic protection against lethal influenza infection." Journal of Immunology 210, no. 1_Supplement (2023): 223.20. http://dx.doi.org/10.4049/jimmunol.210.supp.223.20.

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Abstract Influenza A virus (IAV) is a negative strand RNA virus that undergoes antigenic drift and shift, leading to serologically distinct strains that can cause tens of thousands of deaths annually in the US. The wide variety of hemagglutinin (HA) and neuraminidase (NA) proteins necessitates yearly reformulation of the vaccine to protect against novel seasonal and pandemic strains. Current IAV vaccines do not contain adjuvants, however, immune modulators such as pattern recognition receptor (PRR) agonists may enhance antigen presentation to T cells and provide broader protection against IAV
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8

Aragão, Gilbraz De Souza. "TENORIO MACIEL, Creômenes. «Pâque du Christ dans la Pâque du peuple, Pâque du peuple dans la Pâque du Christ: une lecture de l’oeuvre de l’inculturation liturgique de Jacques Trudel». Paris, 2017. Dissertação (Mestrado em Teologia) – Faculté de Théologie et de Sciences Religieuses, Institut Catholique de Paris, 2017." Revista de Teologia e Ciências da Religião da UNICAP 7, no. 2 (2018): 317. http://dx.doi.org/10.25247/2237-907x.2017v7n2.p317-321.

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Com muito gosto lemos a dissertação de Creômenes Tenorio Maciel, intitulada «Pâque du Christ dans la Pâque du peuple, Pâque du peuple dans la Pâque du Christ: une lecture de l’oeuvre de l’inculturation liturgique de Jacques Trudel». Foi aprovada pelo Júri das Licenças Canônicas do Theologicum (Faculté de Théologie et de Sciences Religieuses - Institut Superieur de Liturgie) do Instituto Católico de Paris, neste ano de 2017, tendo como primeiro leitor J. L. Souletie e segundo leitor Philippe Barras. Creômenes é um jovem jesuíta brasileiro que prossegue seus estudos na França, mas busca desenvol
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9

Kabytov, Petr, Nadezhda Kabytova, and Ekaterina Barinova. "History of the Ufa nobility in the scientific works of M.I. Rodnov." OOO "Zhurnal "Voprosy Istorii" 2022, no. 3-2 (2022): 121–30. http://dx.doi.org/10.31166/voprosyistorii202203statyi43.

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The article presents an analysis of the monographs of the leading researcher at the Institute of History, Language and Literature of the Ufa Federal Research Center of the Russian Academy of Sciences, doctor of sciences M. I. Rodnov, which he published in the 2010s. It has been proved that the reconstruction of the history of the Ufa nobility by the researcher was carried out as part of the longite period of 1861-1917, in which he identifies three stages. The scientific significance of published studies aimed at identifying the factors that caused the inefficiency of the economic activity of n
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Wallace, Donald C. "Policy-Making and Canadian Intergovernmental RelationsECONOMIC RESURGENCE AND THE CONSTITUTIONAL AGENDA: THE CASE OF THE EAST COAST FISHERIES. A. Paul Pross and Susan McCorquodale. Kingston: Institute of Intergovernmental Relations, Queen’s University, 1987.TUG OF WAR: OTTAWA AND THE PROVINCES UNDER TRUDEAU AND MULRONEY. David A. Milne. Toronto: Lorimer, 1986.FEDERAL STATE, NATIONAL ECONOMY. Peter M. Leslie. Toronto: University of Toronto Press, 1987.CANADA: THE STATE OF THE FEDERATION 1986. Ed. Peter M. Leslie. Kingston: Institute of Intergovernmental Relations, Queens University, 1987." Journal of Canadian Studies 23, no. 3 (1988): 150–60. http://dx.doi.org/10.3138/jcs.23.3.150.

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11

Kirton, John. "Les contraintes du milieu et la gestion de la politique étrangère canadienne de 1976 à 1978." Études internationales 10, no. 2 (2005): 321–49. http://dx.doi.org/10.7202/700943ar.

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The direction and pace of efforts to co-ordinate the foreign policy making process within the executive branch of middle-size states may depend on subtle but cumulatively important shiefs in domestic and external environments. The experience of the Canadian government from 1976 to 1978 suggests the effects which four types of environmental change can have. The approach of a federal election was accompanied by a reduced emphasis on the formal procedures of the structured cabinet committee System instituted in the early years of the first Trudeau government. An increased threat to national unity
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12

Valenzuela, Pilar M. "BARBARA TRUDELL. Más allá del aula bilingüe. Comunidades y Culturas Peruanas Nº 26. Ministerio de Educación-Instituto Lingüístico de Verano: Lima: ILV, 1995; 192 pp." Lexis 21, no. 1 (1997): 151–55. http://dx.doi.org/10.18800/lexis.199701.009.

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13

Klasiček, Dubravka. "Sloboda volje ugovornih strana u kontekstu adhezijskih ugovora, s naglaskom na ugovore sklopljene putem informatičke mreže." Filozofska istraživanja 42, no. 1 (2022): 105–29. http://dx.doi.org/10.21464/fi42106.

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U 21. stoljeću možemo reći da živimo u »novom normalnom« vremenu, kada pravo – i općenito čovjekov život – promatramo kroz prizmu sveprisutne digitalne tehnologije. Digitalna tehnologija već duže vrijeme uvelike utječe na kompletno društveno funkcioniranje, a samim time i na tradicionalne institute građanskog prava, kao što su pravo vlasništva, nasljeđivanje i sklapanje ugovora. Tehnologija ove institute dovodi u novo, digitalno, okruženje, pri čemu je potrebno uvažavati posebnosti tog okruženja. Načelo dispozitivnosti jedno je od temeljnih načela građanskog prava koje posebno do izražaja dola
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14

Zadorozhnyuk, Ella, and Yulia Kalinina. "[Rev.] Gorshkov M.K., Sheregi F.E., Tyurina I.O. Vosproizvodstvo Spetsialistov Intellektual’nogo Truda: Sotsiologicheskii Analiz. [Reproduction of Specialists in Intellectual Labor: Sociological Analysis.] Moscow: FNISC RAN publ., 2023." Sociological Journal 29, no. 3 (2023): 178–90. http://dx.doi.org/10.19181/socjour.2023.29.3.11.

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Based on the results of empirical studies on the problems of reproduction of specialists carried out in 2017–2021, the Institute of Sociology of FCTAS RAS and the Center for Social Forecasting and Marketing discuss the trends in the processes of reproduction of different groups of specialists in intellectual labor, as well as their employment. The book analyzes the dynamically changing conditions for the professional self-realization of graduates and their adaptation, discusses difficulties with the reproduction of engineering and technical specialists, justifies recommendations for overcoming
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15

Dimianenko, Anna. "“THE FIRST WORK OF AN INEXPERIENCED WRITER”.EKATERINA PRIVALOVA ABOUT THE BOOK BY M. GLADKOVA." Children's Readings: Studies in Children's Literature 20, no. 2 (2021): 230–57. http://dx.doi.org/10.31860/2304-5817-2021-2-20-230-257.

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This article is an introduction to materials from the Archive of the Institute of Russian Literature (Pushkin House) of the Russian Academy of Sciences, a typewritten article “O pervom trude neopytnoy pisatel’nitsy” (On the first work of an inexperienced writer), found in the personal archive of E. P. Privalova and previously never published. The year the text was written, 1975, was established presumably based on the date on the folder in which the other works of the author were kept. The article provides brief background information on the author of the article — researcher of the history of
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16

Sens, Allen. "Whither Canada: The Canadian Foreign and Defence Policy DebateTHE NAME OF THE CHAMBER WAS PEACE. Ed. Janis Alton, Eric Fawcett, and L. Terrell Gardner. Toronto: Samuel Stevens, 1988.THE ROAD TO PEACE. Ed. Ernie Regehr and Simon Rosenblum. Toronto: James Lorimer, 1988.LAWYERS AND THE NUCLEAR DEBATE. Ed. Maxwell Cohen and Margaret E. Gouin. Ottawa: University of Ottawa Press, 1988.CANADA: THE MILITARY AND STRATEGIC PAWN. GerardS. Vano. New York: Praeger Publishers, 1988.PIROUETTE: PIERRE TRUDEAU AND CANADIAN FOREIGN POLICY. J.L. Granatstein and Robert Bothwell. Toronto: University of Toronto Press, 1990.DIPLOMACY OF FEAR: CANADA AND THE COLD WAR 1941-1948. Denis Smith. Toronto: University of Toronto Press, 1988.AIRWAR 2000. Ed. Brian MacDonald. Toronto: Canadian Institute of Strategic Studies, 1989.IN PURSUIT OF PEACE AND WESTERN SECURITY. William A.B. Campbell and Richard K. Melchin. Vancouver: The Canadian Conservative Centre, 1988." Journal of Canadian Studies 25, no. 4 (1991): 151–62. http://dx.doi.org/10.3138/jcs.25.4.151.

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17

Chimbo Acuña, Emily Gabriela, Karen Gabriela Valverde Zambrano, and Iván Altamirano. "Factores de riesgo asociados a metástasis en pacientes con cáncer de próstata." Oncología (Ecuador) 32, no. 3 (2022): 273–81. http://dx.doi.org/10.33821/658.

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Introducción: El cáncer de próstata (CP) el segundo cáncer diagnosticado en hombres, con mayor incidencia a los 66 años. La obesidad, el tabaquismo, alcoholismo y antecedentes familiares de CP se han encontrado asociados al riesgo de metástasis. El objetivo del presente estudio fue medir la asociación entre factores y el estado metastásico en pacientes con CP en un centro único de referencia en Ecuador.
 Metodología: El presente estudio analítico, se realizó en el Hospital “Teodoro Maldonado Carbo”, en Guayaquil-Ecuador, en el período enero-diciembre del 2019. El cálculo muestral fue no p
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18

Kryshtal, Halyna. "Dimension spirituelle en évidence dans le domaine de la santé par la profession des intervenants en soins spirituels (exemple du Québec)." Roczniki Teologiczne 67, no. 3 (2020): 27–42. http://dx.doi.org/10.18290/rt.20673-2.

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Uwydatnienie wymiaru duchowego w dziedzinie zdrowia poprzez zawód pracowników opieki duchowej (przykład prowincji Quebec)
 Obserwujemy ogromne zmiany w społeczeństwach, które wcześniej uchodziły za chrześcijańskie. Fala zeświecczenia doprowadziła do tego, że szkoły lub szpitale katolickie, prowadzone kiedyś przez zgromadzenia zakonne, znalazły się w rękach świeckiego państwa z odpowiednio świecką ideologią. Prowincja Quebec nie jest wyjątkiem. Właśnie Kościół Katolicki był tą instytucją, która dbała przede wszystkim o wymiar duchowy człowieka w powierzonych sobie ośrodkach. Opiekę duchową
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Trudel, Suzanne, Adam D. Cohen, Amrita Y. Krishnan, et al. "Cevostamab Monotherapy Continues to Show Clinically Meaningful Activity and Manageable Safety in Patients with Heavily Pre-Treated Relapsed/Refractory Multiple Myeloma (RRMM): Updated Results from an Ongoing Phase I Study." Blood 138, Supplement 1 (2021): 157. http://dx.doi.org/10.1182/blood-2021-147983.

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Abstract Background: Fc receptor-homolog 5 (FcRH5) is a type I membrane protein that is expressed exclusively in the B-cell lineage, and at a higher level on myeloma cells than on normal B cells. Cevostamab is a FcRH5xCD3 bispecific antibody (BsAb) that facilitates T cell-directed killing of myeloma cells. Initial data from the dose-escalation phase of the ongoing Phase I study (NCT03275103) of cevostamab monotherapy in patients (pts) with heavily pre-treated RRMM demonstrated promising activity and manageable safety, along with near ubiquitous FcRH5 expression on myeloma cells (Cohen et al. A
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Magaš, Damir. "Mirjana Polić Bobić: Kalifornijski zapisi oca Ferdinanda Konšćaka iz Družbe Isusove, Hrvatska sveučilišna naklada, Zagreb, 2015." Geoadria 21, no. 1 (2016): 167. http://dx.doi.org/10.15291/geoadria.170.

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Mirjana POLIĆ BOBIĆ: Kalifornijski zapisi oca Ferdinanda Konšćaka iz Družbe Isusove, Hrvatska sveučilišna naklada, Zagreb, 2015.U ovoj knjizi autorica je iscrpno i kompetentno, kao ponajbolji prevodilac pisane ostavštine Ferdinanda Konšćaka, analitički i metodološki kvalitetno, uz podrobna objašnjenja i popratna razmišljanja, na tristo stranica predstavila bogatu i vrijednu pisanu ostavštinu kao i relevantne spise o njegovom radu i o njemu. To je do sada najsveobuhvatniji pristup obradi spisa ovoga pripadnika Družbe Isusove u nas, koji uvelike pridonosi spoznaji o veličini i značenju njegovih
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"Canadian Perimeter Institute funding confirmed by Prime Minister Trudeau." Physics Today, 2016. http://dx.doi.org/10.1063/pt.5.029749.

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Kaplan, Louis. "“War is Over! If You Want It”." M/C Journal 6, no. 1 (2003). http://dx.doi.org/10.5204/mcj.2140.

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According to media conglomerate CNN, John Lennon and Yoko Ono’s peace crusade began in 1971. CNN’s on-line news group Showbiz on June 22, 1997 frames John and Yoko’s campaign for peace: “Former Beatle John Lennon was honoured posthumously Friday for his contributions to world peace at a star-studded ceremony in London for the 22nd Silver Clef awards. Lennon’s song “Imagine” has been a leading anthem for the peace movement”. This is a rather limited selection that overlooks a number of earlier (and more radical) possibilities in the Lennon-Ono musical arsenal. A 1969 article in Newsweek entitle
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23

"Language learning." Language Teaching 38, no. 3 (2005): 123–32. http://dx.doi.org/10.1017/s0261444805222991.

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05–225Acevedo Butcher, Carmen (Sogang U, Korea), The case against the ‘native speaker’. English Today (Cambridge, UK) 21.2 (2005), 13–24.05–226Barcroft, Joe & Mitchell S. Sommers (Washington U in St. Louis, USA; barcroft@wustl.edu), Effects of acoustic variability on second language vocabulary learning. Studies in Second Language Acquisition (Cambridge, UK) 27.3 (2005), 387–414.05–227Barr, David, Jonathan Leakey & Alexandre Ranchoux (U of Ulster, UK), Told like it is! An evaluation of an integrated oral development pilot project. Language Learning & Technology (U of Hawaii, Manoa,
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Gagné, Natacha. "Anthropologie et histoire." Anthropen, 2017. http://dx.doi.org/10.17184/eac.anthropen.060.

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On a longtemps vu l’histoire et l’anthropologie comme deux disciplines très distinctes n’ayant pas grand-chose en partage. Jusqu’au début du XXe siècle, l’histoire fut essentiellement celle des « civilisés », des Européens et donc des colonisateurs. Si les colonisés n’étaient pas complètement absents du tableau, ils étaient, au mieux, des participants mineurs. L’anthropologie, pour sa part, s’est instituée en ayant pour objet la compréhension des populations lointaines, les « petites sociétés », autochtones et colonisées, ces populations vues comme hors du temps et de l’histoire. Cette situati
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