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Relevant bibliographies by topics / Trypanosomiasis in animals – Vaccination

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Academic literature on the topic 'Trypanosomiasis in animals – Vaccination'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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Journal articles on the topic "Trypanosomiasis in animals – Vaccination"

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MAGEZ, STEFAN, GUY CALJON, THAO TRAN, BENOÎT STIJLEMANS, and MAGDALENA RADWANSKA. "Current status of vaccination against African trypanosomiasis." Parasitology 137, no. 14 (May 5, 2010): 2017–27. http://dx.doi.org/10.1017/s0031182010000223.

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SUMMARYAnti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigentic variation of the parasite surface coat has been considered the major obstacle in the development of a functional vaccine, recent research into the biology of B cells has indicated that the problems might go further than that. This paper reviews past and current attempts to design both anti-trypanosome vaccines, as well as vaccines directed towards the inhibition of infection-associated pathology.

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La Greca, Florencia, and Stefan Magez. "Vaccination against trypanosomiasis." Human Vaccines 7, no. 11 (November 2011): 1225–33. http://dx.doi.org/10.4161/hv.7.11.18203.

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Lun, Z. R., Y. Fang, C. J. Wang, and R. Brun. "Trypanosomiasis of domestic animals in China." Parasitology Today 9, no. 2 (February 1993): 41–45. http://dx.doi.org/10.1016/0169-4758(93)90029-f.

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Ross, Carol A. "Chemotherapy for trypanosomiasis." Tropical Animal Health and Production 24, no. 1 (March 1992): 28. http://dx.doi.org/10.1007/bf02357231.

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NANTULYA, V. M. "Trypanosomiasis in domestic animals : the problem of diagnosis." Revue Scientifique et Technique de l'OIE 9, no. 2 (June 1, 1990): 357–67. http://dx.doi.org/10.20506/rst.9.2.507.

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MAHARJAN, MAHENDRA, and DINESH R. MISHRA. "Trypanosomiasis in Domestic Animals of Makwanpur District, Nepal." Annals of the New York Academy of Sciences 1081, no. 1 (October 2006): 320–21. http://dx.doi.org/10.1196/annals.1373.042.

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HOLMES, P. H., E. KATUNGUKA-RWAKISHAYA, J. J. BENNISON, G. J. WASSINK, and J. J. PARKINS. "Impact of nutrition on the pathophysiology of bovine trypanosomiasis." Parasitology 120, no. 7 (May 2000): 73–85. http://dx.doi.org/10.1017/s0031182099005806.

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Trypanosomiasis is a major veterinary problem over much of sub-Saharan Africa and is frequently associated with undernutrition. There is growing evidence that nutrition can have a profound effect on the pathophysiological features of animal trypanosomiasis. These features include anaemia, pyrexia, body weight changes, reduced feed intake and diminished productivity including reduced draught work output, milk yield and reproductive capacity. Anaemia is a principal characteristic of trypanosomiasis and the rate at which it develops is influenced by both protein and energy intakes. Pyrexia is associated with increased energy demands for maintenance which is ultimately manifested by reductions in voluntary activity levels and productivity. Weight changes in trypanosomiasis are markedly influenced by the levels of protein intake. High intakes allow infected animals to grow at the same rate as uninfected controls providing energy intake is adequate whilst low energy levels can exacerbate the adverse effects of trypanosomiasis on body weight. Reductions in feed intake are less apparent in animals which are provided with high protein diets and where intake is limited by the disease animals will often exhibit preferential selection of higher quality browse. Further studies are required to evaluate the minimum levels of protein and energy supplementation required to ameliorate the adverse effect of trypanosomiasis, the nature and quality of protein supplement to achieve these benefits and the influence these have on digestive physiology.

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Dirie, Mohamed F., Musa A. Wardhere, and Mohamed A. Farah. "Sheep trypanosomiasis in Somalia." Tropical Animal Health and Production 20, no. 1 (March 1988): 45–46. http://dx.doi.org/10.1007/bf02239645.

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Magez, Stefan, and Magdalena Radwanska. "African trypanosomiasis and antibodies: implications for vaccination, therapy and diagnosis." Future Microbiology 4, no. 8 (October 2009): 1075–87. http://dx.doi.org/10.2217/fmb.09.65.

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Baral, Toya Nath. "Immunobiology of African Trypanosomes: Need of Alternative Interventions." Journal of Biomedicine and Biotechnology 2010 (2010): 1–24. http://dx.doi.org/10.1155/2010/389153.

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Trypanosomiasis is one of the major parasitic diseases for which control is still far from reality. The vaccination approaches by using dominant surface proteins have not been successful, mainly due to antigenic variation of the parasite surface coat. On the other hand, the chemotherapeutic drugs in current use for the treatment of this disease are toxic and problems of resistance are increasing (see Kennedy (2004) and Legros et al. (2002)). Therefore, alternative approaches in both treatment and vaccination against trypanosomiasis are needed at this time. To be able to design and develop such alternatives, the biology of this parasite and the host response against the pathogen need to be studied. These two aspects of this disease with few examples of alternative approaches are discussed here.

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Dissertations / Theses on the topic "Trypanosomiasis in animals – Vaccination"

1

Smuts, Celia Margaretha. "Development of tools to improve the detection of Trypanoma evansi in Australia /." Murdoch University Digital Theses Program, 2009. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20090709.113425.

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Tchamo, Cesaltina da Conceicao Lopes Menete. "Evaluation of the pathogenicity in goats of Trypanosoma congolense from Matutuine, Mozambique." Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-04212008-143822/.

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Knight-Jones, Theo. "Field evaluation of foot-and-mouth disease vaccination in Turkey." Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618321.

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Yu, Chun-I. Palucka Karolina Banchereau Jacques. "Humanized mice to test vaccination against influenza virus via dendritic cells." Waco, Tex. : Baylor University, 2008. http://hdl.handle.net/2104/5184.

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Thesis (Ph.D.)--Baylor University, 2008.
In abstract the '2' and '-/-' in NOD-SCID-[beta]2m-/- is superscript. In abstract the '+' after CD34 and CD8 is superscript. In abstract the '-' and '+' in CD45RA-CD27+CD4+ are superscript. Includes bibliographical references (p. 103-123).

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O'Quin, Jeanette M. "Prophylactic Animal Rabies Vaccination Requirements in Ohio and Involvement of Local Health Departments in Low Cost Rabies Vaccination Clinics." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1322617160.

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La, Tom. "Characterisation, recombinant expression and immunogenicity of BHLP29.7, an outer membrane lipoprotein of Brachyspira hyodysenteriae." La, Tom (2006) Characterisation, recombinant expression and immunogenicity of BHLP29.7, an outer membrane lipoprotein of Brachyspira hyodysenteriae. PhD thesis, Murdoch University, 2006. http://researchrepository.murdoch.edu.au/140/.

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Swine dysentery (SD) is an important endemic infection in many piggeries, and control can be problematic. In this study, the gene encoding a 29.7 kDa outer membrane lipoprotein of the causative intestinal spirochaete Brachyspira hyodysenteriae, was identified and sequenced. An 816 bp hypothetical open reading frame (ORF) was identified, with a potential ribosome binding site, and putative -10 and -35 promoter regions upstream from the start of the ORF. The 29.7 kDa outer membrane lipoprotein was designated Bhlp29.7 and the encoding gene named bhlp29.7. The amino acid sequence of Bhlp29.7 included a 19 residue hydrophobic signal peptide, incorporating a potential signal peptidase cleavage site and membrane lipoprotein lipid attachment site. In silico analysis of this protein together with lipidation studies further supported its probable outer membrane localisation. Comparison of the Bhlp29.7 sequence with public sequence databases showed that it had up to 40% similarity with the D-methionine substrate-binding outer membrane lipoprotein (MetQ) of a number of bacterial pathogens. The Bhlp29.7 gene was detected in all 48 strains of B. hyodysenteriae examined, and in Brachyspira innocens strain B256T, but not in 10 other strains of B. innocens or in 42 strains of other Brachyspira spp. The gene was sequenced from B. innocens strain B256T and from 11 strains of B. hyodysenteriae. The B. hyodysenteriae genes shared 97.9-100% nucleotide sequence identity and had 97.5-99.5% identity with the gene of B. innocens strain B256T. The Bhlp29.7 gene was subsequently cloned and expressed as a histidine fusion protein in an Escherichia coli expression system. An ELISA test using recombinant his-tagged Bhlp29.7 (His6-Bhlp29.7) as the detecting antigen was developed and evaluated. The threshold value of the test was chosen to provide a highly stringent assessment of the disease status of a herd. The sensitivity and specificity of the test was 100%. When the test was applied to sera from eight herds with suspected SD, four gave ELISA values indicating that the herds were diseased. The remaining four herds gave ELISA values below the threshold value. These results indicated that the Bhlp29.7-ELISA was useful as an indirect test for exposure of a herd to B. hyodysenteriae and may be a helpful complement to current methods of SD diagnosis. Recombinant His6-Bhlp29.7 was evaluated as a vaccine subunit for prevention of SD. The His6-Bhlp29.7 was shown to be immunogenic in mice following two intramuscular injections. Vaccination of mice with His6-Bhlp29.7 provided full protection after oral challenge with B. hyodysenteriae. In two experiments, intramuscular and oral vaccination of pigs with the His6-Bhlp29.7 resulted in a 50% reduction in incidence of SD compared to unvaccinated control pigs (P=0.047). This is the first subunit vaccine shown to provide pigs with protection from SD. Further work is needed to optimise delivery routes and adjuvants for commercial development of the vaccine.

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Idachaba, Stella Ejura. "Status of canine vaccination and the prevalence of rabies in humans and dogs in Plateau State, Nigeria 1998-2007." Pretoria : [s.n.], 2010. http://upetd.up.ac.za/thesis/available/etd-02252010-104653/.

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Schaten, Kathrin Maria. "One Health approach to measure the impact on wellbeing of selected infectious diseases in humans and animals in Zambia." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33198.

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This study describes the results of a cross-sectional survey conducted in Mambwe district in the Eastern Province in Zambia. It uses a One Health approach to assess the impact of veterinary, medical, environmental and social determinants on animal and human health and wellbeing. One Health is defined as a holistic and interdisciplinary approach that describes the complexities between people, animals, the environment and their health. Human wellbeing is defined in this thesis as 'a condition in which all members of society are able to determine and meet their needs and have a large range of choices to meet their potential' (Prescott-Allen, 2001). As a first step, eight focus group discussions with the inhabitants followed by key informant interviews with stakeholders in the area were conducted to give a primary impression and narrow down the problems in relation to animal and human health of the area in general. Following this, a randomized selection of 210 households was visited and in each household blood samples were taken from all humans and all animals belonging to five animal species, namely cattle, goats, sheep, pigs and dogs. A third of the households did not keep any of the animal species chosen for sampling, but their inclusion was important for the social analysis. In all of these 210 households a wellbeing questionnaire was administered and, for every human and animal sampled, a health questionnaire. The study area falls within the tsetse-infested region of Zambia. It has a high wildlife density reflecting the proximity of several national parks and is historically endemic for both human and animal African trypanosomiasis (HAT&AAT). Therefore humans and animals were tested for trypanosomiasis using internal transcribed spacer (ITS) polymerase chain reaction (PCR). Since it is important as a differential diagnosis, malaria was tested for by a rapid diagnostic test in the field from human blood. Sera from mature individuals from all animal species except pigs were tested in a field laboratory for brucellosis using the Rose Bengal test. Additionally, cattle and dogs were tested for five genera of tick-borne infections (TBI) including Anaplasma, Ehrlichia, Theileria, Babesia and Rickettsia using reverse line blot (RLB) in the laboratory at the University of Edinburgh (UoE). The blood samples for PCR and RLB analysis at UoE were stored on WhatmanTM FTA cards. A total of 1012 human samples were tested for HAT and none found positive. 1005 (seven people had been tested positive or treated against malaria shortly before the sampling) people tested for malaria showed an overall prevalence of 15% (95% CI 13.2-17.7). None of the 734 Rose Bengal tests showed up positive for brucellosis. The prevalence of AAT in 1275 samples tested was much lower compared to former samplings; in cattle 22% (95% CI 18-27.2), in goats 7% (95% CI 4.5-9.2), in pigs 6% (95% CI 3.2-9.4), in dogs 9% (95% CI 5.2-13.6) and no samples were found positive in sheep. The prevalence of TBIs is much more complex with many multiple infections. A total of 340 cattle and 195 dogs were tested. In cattle the number of samples positive for any microorganism was as follows; 92% (95% CI 88- 94.2). Overall there were fewer positive samples from dogs with 25% of animals infected (95% CI 19.2-31.8). The wellbeing and health questionnaires were designed to help to identify possible risk factors for the above-mentioned diseases and signs, such as fever, diarrhoea and seizures, indicative for several other diseases. The results of these surveys might also help to identify potential reasons for a lower or higher prevalence of trypanosomiasis and malaria found than expected from previous studies. Additionally, information on personal happiness, attitudes towards veterinary and medical services, medical treatments received, education, women's reproductive history, drug abuse, people's perceptions of changes in environment and agriculture, demography, poverty and migration were collected via the questionnaires alongside information on livestock demographics and fertility. One of the main conclusions is that both medical and veterinary health care systems suffer from a number of shortcomings. The distance to appropriate treatment and care facilities is far and the necessary drugs are often unavailable. Also, both the knowledge and technology for diagnosing selected diseases is not in place. This study suggests that neurocysticercosis (NCC) plays an important role in this area due to the high number of seizures reported in people, in whom treatment for epilepsy was unsuccessful. Samples taken from a few pigs indicated the presence of Taenia solium, the causal agent of NCC. Furthermore, many of the TBIs are of zoonotic nature and further investigations must be made to begin to assess the burden of these diseases in humans and animals. Environmental changes such as degradation of the vegetation are likely to have an influence on the prevalence of studied diseases and this aspect is being investigated further in other studies. Due to the nature of a cross-sectional study, only limited conclusions can be drawn on the causal relationships of disease prevalence, but the social analysis conducted in this study confirmed the interactions of selected factors related to health and wealth unique for this study area.

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Bruce, Mieghan. "The impact of brucellosis in Albania : a systems approach." Thesis, Royal Veterinary College (University of London), 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701674.

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Viol, Milena Araúz [UNESP]. "Detecção de reações cruzadas por Leishmania spp. e Trypanosoma spp. em cães pelo ensaio imunoenzimático indireto, pela reação de imunofluorescência indireta e reação em cadeia de polimerase." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/94717.

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Made available in DSpace on 2014-06-11T19:27:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-08-18Bitstream added on 2014-06-13T20:16:26Z : No. of bitstreams: 1 viol_ma_me_araca.pdf: 293015 bytes, checksum: bdc10c5bc3d8d20c951f2fc3b6dc7f4e (MD5)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
O objetivo deste estudo foi detectar reações cruzadas por Leishmania spp. e Trypanossoma cruzi pelo Ensaio Imunoenzimático Indireto (ELISA), pela Reação de Imunofluorescência Indireta (RIFI) e pela Reação em Cadeia da Polimerase (PCR). Assim, foram colhidas 408 amostras sanguíneas de cães domiciliados no município de Araçatuba,SP, de ambos os sexos, de diversas raças e com idade a partir de seis meses. Em relação à Leishmania spp., pela RIFI, 14,95 % (61/408) foram reagentes. A positividade por meio do ELISA, foi de 20,10% (82/408) e pela PCR, 29,66% (121/408), com diferença significativa para o sexo e a idade destes animais (p<0,05). Para Trypanosoma spp., a ocorrência de anticorpos pelo ELISA foi de 10,54% (43/408) e pela PCR, 2,45% (10/408) cães foram positivos. Pela RIFI, 10,29% (42/408) dos animais foram considerados positivos e somente o sexo apresentou diferença significativa (p<0,05). Neste trabalho, constatou-se que 10,54%(43/408) dos animais foram soropositivos por ELISA para Trypanosoma spp., sendo que 79,07%(34/43) obtiveram resultados positivos no diagnóstico molecular para Leishmania spp. e dos 10,29% (42/408) positivos por RIFI, 95,24% (40/42) dos cães confirmaram a infecção por este parasita. Por meio dos resultados obtidos, pode-se inferir que foram evidenciadas reações cruzadas nos ensaios sorológicos para ambos os protozoários, nos animais analisados neste trabalho
The aim of this study was to detect cross-infection by Leishmania spp. and Trypanosoma spp. by indirect immunosorbent assay (ELISA), by Indirect Immunofluorescence (IFA) and by the Polymerase Chain Reaction (PCR). Thus, blood samples were collected from 408 domestic dogs of both sexes, different races and ages from six months. For Leishmania spp. by IFA, 14.95% (61/408) were positive. Positive by ELISA, was 20.10% (82/408), and PCR 29.66% (121/408), with significant difference for sex and age of animals (p <0.05). For Trypanosoma spp., the occurrence of antibodies by ELISA, was 10.54% (43/408), and PCR, 2.45% (10/408) dogs were positive. By IFA, 10.29% (42/408) of the animals were considered positive and only sex was significant difference (p <0.05). In this work it was found that 10.54% (43/408) animals were seropositive by ELISA for Trypanosoma spp., 79.07% (34/43) had positive results in molecular diagnostic for Leishmania spp. and 10.29% (42/408) positive by IFA, 95.24% (40/42) dogs confirmed the infection by this parasite. Through the results obtained can be inferred that cross-infection were observed by both protozoa in animals of this paper

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Books on the topic "Trypanosomiasis in animals – Vaccination"

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Swallow, Brent M. Impacts of trypanosomiasis on African agriculture. Rome: Food and Agriculture Organization of the United Nations, 2000.

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Institute, Kenya Trypanosomiasis Research. Strategic plan for KETRI: 1989-2000. Kikuyu, Kenya: KETRI, 1989.

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Institute, Kenya Trypanosomiasis Research. Strategic plan for KETRI: 1990-2000. Kikuyu, Kenya: KETRI, 1991.

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P, Boyt W., ed. A field guide for the diagnosis, treatment and prevention of African animal trypanosomosis. Rome: Food and Agriculture Organization of the United Nations, 1998.

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Institute, Kenya Trypanosomiasis Research. Proceedings of the third KETRI internal review: 6th-10th June 1994. Edited by Omuse John K, Ndungu Joseph, and Alusi P. M. Kikuyu, Kenya: KETRI, 1995.

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Sommāi. Khūmư̄ kānnamsai vaksin samlap sat. [Viangchan]: ʻOngkān Mittaphāp Khavēkkœ̄, Khōngkān Sak Yā Pō̜ngkan Phanyāt Sat, 1991.

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Food and Agriculture Organization of the United Nations. Expert Consultation on the Genetic Aspects of Trypanotolerance. Proceedings of the FAO Expert Consultation on the genetic aspects of trypanotolerance: Held in Rome, Italy, 3-4 September 1991. Rome: Food and Agriculture Organization of the United Nations, 1992.

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Affognon, Hippolyte. Étude des politiques relatives aux stratégies de gestion de la chimiorésistance dans le cadre de la lutte contre la trypanosomose en Afrique de l'ouest: Cas du Mali : gestion de la chimiorésistance dans le cadre de la lutte intégrée contre la trypanosomose dans la zone contonnière de l'Afrique de l'Ouest. Nairobi: International Livestock Research Institute, 2009.

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Sommāi. Khūmư̄ fưkhat sattavaphǣt yū hākthān. [Viangchan]: ʻOngkān Mittaphāp Khavēkkœ̄, Khōngkān Sak Yā Pō̜ngkan Phanyāt Sat, 1991.

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Jacques, Roux. Vaccinations in human and animal brucellosis =: Les vaccinations dans les brucelloses humaines et animales. Karachi: Muhammad Ali Society, 1985.

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Book chapters on the topic "Trypanosomiasis in animals – Vaccination"

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Bunn, T. O. "Vaccines and Vaccination of Domestic Animals." In Developments in Veterinary Virology, 323–33. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1755-5_14.

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Stich, August. "Human African Trypanosomiasis: The Smoldering Scourge of Africa." In Zoonoses - Infections Affecting Humans and Animals, 785–99. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9457-2_31.

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Kuttler, Kenneth L., and Julius P. Kreier. "Hemoprotozoan Infections of Domestic Animals: Trypanosomiasis, Babesiosis, Theileriosis, and Anaplasmosis." In Chemotherapy of Parasitic Diseases, 171–91. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-1233-8_8.

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Czerny, Claus-Peter. "Orthopoxviruses—Plagues of Mankind, Strategists in Immune Evasion, Teachers in Vaccination." In Zoonoses - Infections Affecting Humans and Animals, 497–525. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9457-2_20.

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Baer, G. M. "Rabies Vaccination of Wildlife and Domestic Animals other than Dogs." In Rabies in the Tropics, 270–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70060-6_36.

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Black, Samuel J. "Control of pathogenesis in African animal trypanosomiasis: a search for answers at ILRAD, ILCA and ILRI, 1975-2018." In The impact of the International Livestock Research Institute, 103–47. Wallingford: CABI, 2020. http://dx.doi.org/10.1079/9781789241853.0103.

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Abstract This book chapter describes the management of animal trypanosomiasis: (i) vector control/eradication; (ii) use of trypanocides; and (iii) use of trypanotolerant breeds of cattle. Vector control includes reducing the tsetse fly population with traps and insecticides, and in areas with a high population of trypanosome infected tsetse, animals are prophylactically administered antiparasitic drugs. To date, there is no AAT vaccine available, as discussed below. While disappointing with respect to AAT control, studies of AAT pathogenesis at ILRAD/ILRI did identify the definitive question for immunological research on AAT, namely, how do trypanosomes eliminate TD antibody responses in trypanosomiasis-susceptible mammals? In addition, the work at ILRI on the genetic basis of trypanotolerance contributed a high-density singlenucleotide polymorphism (SNP) map of the bovine genome that has intrinsic value for analysis of QTLs that control other traits, including susceptibility to other diseases.

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Chakarov, Svetoslav, and Nicolas Fazilleau. "Tracking by Flow Cytometry Antigen-Specific Follicular Helper T Cells in Wild-Type Animals After Protein Vaccination." In Methods in Molecular Biology, 39–47. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2498-1_4.

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"Trypanosomiasis, Animals." In Encyclopedia of Parasitology, 2949. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3306.

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Barry, J. D. "African trypanosomiasis." In Vaccination Strategies of Tropical Diseases, 197–217. Routledge, 2017. http://dx.doi.org/10.1201/9780203734513-13.

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Jenkins, M. C. "Vaccination." In Coccidiosis in Livestock, Poultry, Companion Animals, and Humans, 51–58. CRC Press, 2019. http://dx.doi.org/10.1201/9780429294105-4.

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Conference papers on the topic "Trypanosomiasis in animals – Vaccination"

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Abdrakhmanov, S. K., E. E. Mukhanbetkaliyev, A. A. Sultanov, and S. B. Tyulegenov. "EVALUATION OF POST-VACCINAL IMMUNITY AGAINST FMD BROKEN DOWN BY AGE AND GENDER GROUPS IN THE REPUBLIC OF KAZAKHSTAN." In STATE AND DEVELOPMENT PROSPECTS OF AGRIBUSINESS. DSTU-PRINT, 2020. http://dx.doi.org/10.23947/interagro.2020.1.23-25.

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The article provides an analysis of monitoring of post-vaccination immunity against foot and mouth disease, stratified by age and gender groups. Evaluation of induced immunity broken down by age and gender groups is the main element of post-vaccination monitoring, which allows not only to assess the quality of vaccination, but also to determine the timing for achieving the necessary immunity among vaccinated animals.

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Burg, Sjoerd H. Van Der, Tetje C. van der Sluis, Helene van Meir, Judith R. Kroep, Gemma G. Kenter, Mariette I. E. van Poelgeest, Koos Burggraaf, Cornelis J. M. Melief, and Marij J. P. Welters. "Abstract 2938: Synergistic effects of properly timed HPV16 synthetic long peptide vaccination during standard carboplatin-paclitaxel chemotherapy in animals and in patients with metastatic cervical carcinoma." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2938.

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