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Journal articles on the topic 'Tryptophane'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 July 2024

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1

Bondareva, N. A., P. P. Purygin, Yu P. Zarubin, P. V. Dorovatovskii, A. A. Korlyukov, and A. V. Vologzhanina. "Synthesis, Structure, and Electron Density Distribution in Crystals of K2(L-Trp)2(H2O) (HTrp = Tryptophane)." Координационная химия 49, no. 5 (May 1, 2023): 269–77. http://dx.doi.org/10.31857/s0132344x2260031x.

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The first salt of alkaline metal and L-tryptophane, K2(L-Trp)2(H2O) (I), is synthesized by the reaction of L-tryptophane (HTrp) with potassium hydroxide in an aqueous-alcohol solution. Compound I is characterized by IR and 1H NMR spectroscopy and X-ray diffraction (XRD) (CIF file CCDC no. 2184367). Compound I is found to have a layered structure due to the presence of the bridging water molecule and chelate-bridging anions. The quantum chemical calculations of the crystal structure (PBE, plane-wave basis set, 800 eV) is used to evaluate the strength of interactions of the potassium ion with the L-tryptophanate anion (depending on the coordination type) and the influence of the anion conformation on the strength of coordination, hydrophobic, and hydrophilic interactions.

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2

Rahim, Barham K., Peshawa O. Amin, Fahmi F. Muhammadsharif, Salah R. Saeed, and Kamal A. Ketuly. "Optical and Optoelectronic Studies of Binary and Ternary Films of Poly(L-Tryptophane), Poly(5-hydroxy-L-tryptophane), and P(TER-CO-TRI) Doped with Sudan Dye." ARO-THE SCIENTIFIC JOURNAL OF KOYA UNIVERSITY 11, no. 1 (April 17, 2023): 105–15. http://dx.doi.org/10.14500/aro.11103.

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In this work, the optical properties and optoelectronics parameters of binary and ternary composite films made of two electron acceptors, poly(L-Tryptophane) and poly(5-hydroxy-L-Tryptophane), with an electron donor, P(TER-CO-TRI), doped with Sudan dyes, are comprehensively investigated. The films with different volumetric ratios of the components were deposited onto the glass substrates using spin coating technique. Results showed that with the help of dye doping into the binary systems of poly(L-Tryptophane):P(TRI-co-TER) (1:2) and poly(5-hydroxy-L-Tryptophane):P(TRI-co-TER)(1:2), the refractive index was increased from 2.01 to 2.32. The nature of the electronic transition in the studied films was found to be a direct allowed transition, which was derived from Tauc’s equation. The combination of Cyclic voltammetry (CV) technique and absorption spectroscopy was used to determine the molecular energy levels, HOMO and LUMO of the polymer samples. It was seen that the mixture of poly(L-Tryptophane):P(TRI-co-TER):Sudan dye (1:2:2) has led to increase the energy gap to 2.95 eV and the real optical conductivity ( ) to about 433.11 S.cm-1. According to the findings, the investigated polymers can have a great potential for semitransparent organic solar cells.

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3

Šustová, Květoslava, and Jana Růžičková. "Analysis of degree maturation of edam cheese by FT Near Infrared Spectroscopy." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 56, no. 1 (2008): 221–28. http://dx.doi.org/10.11118/actaun200856010221.

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This work deals with use of FT NIR spectroscopy to speedy analysis of maturation of edam cheese. Maturation of cheese was study with the measure of soluble nitrogen, tyrosine and tryptophane. This method can be able to make optimal making raw material to production of processed cheese. Samples of edam cheese (45% fat in dry matter) were analysed with time of ripening 7 to 99 days. Soluble nitrogen, tyrosine and tryptophane were analysed on UV–VisSpectrometer (270 and 290 nm). Sequentially samples were analysed on FT NIR spectrometer of two methods: 1) slice of cheese was analysed help with optical probe, 2) grated cheese was analysed on the integration sphere. The values of correlation coefficient of calibration on the integration sphere were as follows: soluble nitrogen 0.922, tyrosine 0.911 and tryptophane 0.852. The values of correlation coefficient of calibration with optical probe were as follows: soluble nitrogen 0.996, tyrosine 0.958 and tryptophane 0.922.

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4

Peng, Shiqi, and Ekkehard Winterfeldt. "Enantiomerically pure Indoloquinolizines from tryptophane." Liebigs Annalen der Chemie 1990, no. 4 (April 12, 1990): 313–18. http://dx.doi.org/10.1002/jlac.199019900159.

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5

Petrovic, Marian, Ivan Talian, Lenka Skantarova, Andrej Orinak, and Dusan Velic. "TOF-SIMS surface analysis of L-Tryptophan self assembled monolayer." Open Chemistry 12, no. 5 (May 1, 2014): 568–76. http://dx.doi.org/10.2478/s11532-014-0515-5.

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AbstractThis paper dealt with the preparation and characterization of self — assembled monolayersSAM-s of 1-hexadecanethiole and mercapto acetic acid on the silver nanostructure and subsequently the immobilization with amino acid L-Tryptophane. In order to achieve it, we used the electrodeposition of silver onto nanostructured surface of paraffin impregnated graphite electrode (PIGE). Subsequently, we assembled SAM by choosing the 1-hexadecanethiole and mercaptoacetic acid. These two kinds of SAM underwent the functionalization by L-Tryptophan. The observations of silver on PIGE surfaces were performed by scanning electron microscope (SEM). For surface analysis of the SAM functionalized by L-tryphophan, the TOF-SIMS technique was chosen. Finally, the fragmented ions of the immobilized-L-Tryptophan SAM were determined on the basis of suggested residues and three-dimensional structure. The residues show that the ability of L-Tryptophan to build homogeneous structure is better by mercaptoacetic acid SAM structure than by 1-hexadecanethiol. It was observed that L-Tryptophan built compact surface, which, due its chemical properties, can represent very interesting side regarding biocompatibility, homochirality and robustness in the area of life science.

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6

Tarasevičienė, Živilė, Aloyzas Velička, and Aurelija Paulauskienė. "Impact of Foliar Application of Amino Acids on Total Phenols, Phenolic Acids Content of Different Mints Varieties under the Field Condition." Plants 10, no. 3 (March 23, 2021): 599. http://dx.doi.org/10.3390/plants10030599.

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Phenolic compounds have a number of benefits to human health and can be used as preventive compounds for the development of some chronic diseases. Mentha plants are not only a good source of essential oils, but also contain significant levels of wide range of phenolic compounds. The aim of this research was to investigate the possibility to increase phenols content in Mentha plants under the foliar application with L-phenylalanine, L-tryptophan, L-tyrosine at two concentrations (100 mg L−1 and 200 mg L−1) and to create preconditions for using this plant for even more diverse purposes. Quantitative and qualitative analyses of phenols in mints were performed by HPLC method. Foliar application of amino acids increased the total phenol content from 1.22 to 3.51 times depending on the treatment and mint variety. The most pronounced foliar application to total phenols content was tryptophane especially in Mentha piperita “Swiss”. Mentha piperita “Swiss” was affected most by foliar application and the amount of total phenolic acids depending on the treatment ranged from 159.25 to 664.03 mg 100 g−1 (DW), respectively, non-sprayed and sprayed with tryptophane 100 mg L−1. Our results suggest that the biophenol content varies according to such factors as foliar application and variety, and every single mint variety has individual response to different applications of amino acids.

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7

di Costanzo-Dufetel, J., and J. Romette. "Acides aminés : 3. Alanine, Proline, Tryptophane." Nutrition Clinique et Métabolisme 5, no. 4 (1991): 247. http://dx.doi.org/10.1016/s0985-0562(05)80272-9.

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8

HENRY, Y. "Affinement du concept de la protéine idéale pour le porc en croissance." INRAE Productions Animales 6, no. 3 (June 28, 1993): 199–212. http://dx.doi.org/10.20870/productions-animales.1993.6.3.4200.

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Cet article traite des données récentes sur les relations d’équilibre entre les acides aminés dans l’alimentation du porc en croissance, au travers du concept de la protéine "idéale". Après avoir précisé les limites de ce concept, sur le plan de la constance des rapports entre les teneurs en acides aminés indispensables et celle en lysine, prise comme référence, sont considérés les ratios entre les acides aminés limitants secondaires (tryptophane, thréonine, méthionine et acides aminés soufrés) et la lysine, compte tenu des spécificités de leur rôle fonctionnel au plan métabolique et physiologique. Pour cela, l’incidence des écarts entre le profil de composition en acides aminés de la protéine alimentaire et celui de la protéine idéale (excès de protéines) sur l’ingestion alimentaire et les performances de croissance est étudiée selon la nature de l’acide aminé le plus limitant. En raison de sa faible contribution aux processus métaboliques autres que ceux concernant la synthèse de protéines corporelles, la lysine constitue une référence stable pour l’expression des rapports entre les acides aminés. A la différence de la lysine, le tryptophane interagit fortement et négativement avec les protéines excédentaires (acides aminés neutres de grande taille) au niveau de l’appétit et de la croissance, en liaison avec un dysfonctionnement du système sérotoninergique. Ceci met en défaut la constance du rapport tryptophane / lysine, qui devrait être corrigé sur la base d’un ratio minimum tryptophane / acides aminés neutres de 4 %, pour se prémunir d’un risque d’excès de ces derniers dans certaines protéines alimentaires. Dans le cas de la thréonine, lorsqu’elle est limitante, il ressort une interaction positive avec les acides aminés non indispensables (acide glutamique). L’équilibre méthionine / cystine a été reconsidéré en fonction des données récentes de la bibliographie. En conclusion, les recommandations concernant les rapports acides aminés / lysine pour le porc en croissance ont été réactualisées.

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9

Kamilova, Faina, Lev V. Kravchenko, Alexander I. Shaposhnikov, Tatiyana Azarova, Nataliya Makarova, and Ben Lugtenberg. "Organic Acids, Sugars, and l-Tryptophane in Exudates of Vegetables Growing on Stonewool and Their Effects on Activities of Rhizosphere Bacteria." Molecular Plant-Microbe Interactions® 19, no. 3 (March 2006): 250–56. http://dx.doi.org/10.1094/mpmi-19-0250.

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The influence of stonewool substrate on the exudation of the major soluble carbon nutrients and of the auxin precursor tryptophane for Pseudomonas biocontrol agents was studied. To this end, the composition of the organic acids and sugars, as well that of tryptophane, of axenically collected exudates of seed, seedlings, and roots of tomato, cucumber, and sweet pepper was determined. The major results were as follows. i) The total amount of organic acid is much higher than that of total sugar. ii) Exudation of both organic acids and sugars increases during plant growth. iii) Citric, succinic, and malic acids represent the major organic acids, whereas fructose and glucose are the major sugars. iv) Compared with glass beads as a neutral substrate, stonewool substantially stimulates exudation of organic acids and sugars. v) It appeared that enhanced root-tip-colonizing bacteria isolated previously from the rhizosphere of tomato and cucumber grow much better in minimal medium with citrate as the sole carbon source than other, randomly selected rhizobacteria do. This indicates that the procedure which selects for excellent root-tip colonizers enriches for strains which utilize the major exudate carbon source citrate. vi) The content of L-tryp-tophane, the direct precursor of auxin, is approximately 60-fold higher in seedling exudates of tomato and sweet pepper than in cucumber seedling exudates, indicating a higher possibility of plant growth stimulation after inoculation with auxin-producing rhizobacteria for tomato and sweet pepper crops than for cucumber. However, the biocontrol strain Pseudomonas fluorescens WCS365, which is able to convert tryptophane into auxin, did not stimulate growth of these three crops. In contrast, this strain did stimulate growth of roots of radish, a plant which exudes nine times more tryptophane than tomato does.

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10

Shamilov, E. N., A. S. Abdullaev, M. M. Farajov, V. E. Shamilli, Sh I. Gahramanova, and F. F. Jalaladdinov. "Synthesis, characterization and antiradiation properties of the tryptophanates of cobalt (II), manganese (II), copper (II) and zinc." Faktori eksperimental'noi evolucii organizmiv 26 (September 1, 2020): 154–57. http://dx.doi.org/10.7124/feeo.v26.1259.

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Aim. In order to study the radioprotective activity were were obtained in the tryptophanates of cobalt (II), manganese (II), copper (II) and zinc. Methods. The composition and structure of the complexes were studied by elemental, thermogravimetric analyzes and IR infrared spectroscopy. To determine the presence of the Radioprotective Properties of the Co (II), Mn (II), Cu (II), Zn complexes with tryptophane, a test was conducted for the 30-day survival of irradiated animals. Results. The results of thermogravimetric studies have shown that the final product of the thermal decomposition of all compounds is metal oxide, respectively. The method of IR spectroscopy showed that the ligands in the composition of the metal (II) complexes enter the neutral form and coordinate with the complexing agent through the nitrogen atom. The results of experiments with complexes showed that they have noticeable radioprotective activity. The radioprotective activity of Co (II) complexes with tryptophan is 55%, Mn (II) with tryptophan 50%, Cu (II) with tryptophan 40%, and Zn 30%. They improve the survival and average life expectancy of lethally irradiated mice, not reaching the level of the known cystamine radioprotector, which is 80%. Conclusions. The data obtained by us testify to the prospects of using the complexes of Co (II), Mn (II), Cu (II), Zn with tryptophan for preventive purposes and in order to prevent local radiation injuries. Keywords: tryptophan-metal complexes, IR spectroscopy, thermogravimetry, complex compounds, radioprotective properties.

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11

Haas, Ch, S. Duhurt, W. Lowenstein, and H. Durand. "Myalgies et hyperéosinophilie liées au L-tryptophane." La Revue de Médecine Interne 11, no. 3 (May 1990): S37. http://dx.doi.org/10.1016/s0248-8663(05)81942-3.

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12

Ito, H., H. Shiokawa, M. Torii, and T. Suzuki. "Effects of Tryptophane on Shrsp Offspring Growth." Clinical and Experimental Hypertension. Part A: Theory and Practice 13, no. 5 (January 1991): 971–79. http://dx.doi.org/10.3109/10641969109042103.

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13

Journal, Baghdad Science. "Stability constant measurements of thorivm (lv) and uranyle ions with some amino acids." Baghdad Science Journal 1, no. 1 (March 7, 2004): 8–12. http://dx.doi.org/10.21123/bsj.1.1.8-12.

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14

Williams, R. C., E. Kievit, N. Tsuchiya, C. Malone, and L. Hutt-Fletcher. "Differential mapping of Fc gamma-binding and monoclonal antibody-reactive epitopes on gE, the Fc gamma-binding glycoprotein of herpes simplex virus type 1." Journal of Immunology 149, no. 7 (October 1, 1992): 2415–27. http://dx.doi.org/10.4049/jimmunol.149.7.2415.

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Abstract The entire 396 residue extracellular sequence of gE the HSV-1 Fc gamma-binding glycoprotein has been studied to determine epitopes binding to two mAb II-481 and 88S previously demonstrated to react with gE at or near the Fc gamma-binding regions. Overlapping 7-mers constructed from the established sequence were tested with mAb II-481 and 88S along with their Fab fragments. Control mAb of the same IgG 2b subclass as well as whole rabbit and human IgG and Fc were also tested for binding to overlapping linear sequences using the ELISA pin assay to map Fc gamma-binding regions. Six sequences PKTSWRRVS, GLYTLSV, QVASVVLVVQP, PAPPRSWP, CLYHPQLP, and ASTWTSRL were found that constituted major regions binding to the two different mAb of the same specificity. Glycine substitution for each residue within these sequences indicated that arginine 29, tryptophane 70, valine 144, valine 157, arginine 208, histidine 283, and arginine 305 constituted important portions of the II 481 mAb-reactive epitope. Many of the same regions along with one other, GPLHPSW, appeared to be involved in Fc gamma binding. Substitution of glycine for each residue indicated that histidine 67, tryptophane 70, valine 71, valine 157, valine 158, valine 160, valine 161, tryptophane 210, serine 279, cysteine 280, leucine 281, tyrosine 282, histidine 283, proline 284, glutamine 285, proline 287, tryptophane 302, and arginine 305 were important for Fc gamma-binding. Inhibition by gE peptides of rosetting of E sensitized with rabbit IgG antibody around HSV-1-infected cells, as well as inhibition of rosetting using F(ab)2 fragments of rabbit antibodies to these peptides was used to assay relative contributions of all seven regions to Fc gamma-binding activity. Our results provide a tentative map of mAb binding and Fc gamma-reactive sites on gE. mAb and Fc gamma binding of a limited number of individual antigenic amino acids widely distributed among the separate reactive regions suggest that many of the same separate residues contribute both to antigenicity as well as to Fc gamma-binding activity.

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15

Suhareva, T. N., V. A. Babushkin, A. S. Ratushny, K. I. Toporkova, and N. Yu Tolstova. "Optimal composition of poultry balls based on natural brown flax bran." IOP Conference Series: Earth and Environmental Science 845, no. 1 (November 1, 2021): 012080. http://dx.doi.org/10.1088/1755-1315/845/1/012080.

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Abstract The paper established that depending on the number of natural brown flax bran and squash the prefabricated poultry meat does not significantly change its indicators, but the most optimal is sample No. 2 – with the replacement of the wheat bread norm with 50% natural brown flax bran; with the replacement of the water norm with 50% squash – Kurazh. The content of amino acids in Kurazh balls was higher than in the control sample, which indicates their biological value and quality. The study of the content of such acute deficient amino acids as lysine, methionine and tryptophan showed that the Kurage balls exceed the control sample in amino acids: lysine – by 77.6%, methionine – by 125.5%, tryptophane – by 78.1, respectively. A new kind of balls with functional ingredients has a number of useful properties for the human body and may be recommended for gerodietetic nutrition.

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16

Akbarzadeh, Azim, Davood Zare, Ali Farhangi, Mohammad Reza Mehrabi, Dariush Norouzian, Shahram Tangestani, Majid Moghadam, and Nasim Bararpour. "Synthesis and Characterization of Gold Nanoparticles by Tryptophane." American Journal of Applied Sciences 6, no. 4 (April 1, 2009): 691–95. http://dx.doi.org/10.3844/ajas.2009.691.695.

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17

Akbarzadeh. "Synthesis and Characterization of Gold Nanoparticles by Tryptophane." American Journal of Applied Sciences 6, no. 4 (April 1, 2009): 691–95. http://dx.doi.org/10.3844/ajassp.2009.691.695.

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18

Körner, E., G. Bertha, E. Flooh, B. Reinhart, R. Wolf, and H. Lechner. "Sleep-Inducing Effect of L-Tryptophane." European Neurology 25, no. 2 (1986): 75–81. http://dx.doi.org/10.1159/000116087.

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19

Dell Isola, B., J. M. Thiollieres, J. Labrousse, and J. Cl Valcke. "Péricardite aiguë avec éosinophilie après ingestion de tryptophane." La Revue de Médecine Interne 13, no. 7 (December 1992): S549. http://dx.doi.org/10.1016/s0248-8663(05)81128-2.

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20

Wang, Yinglu, Qian Zheng, Li Li, Lile Pan, and Hu Zhu. "Anti-Quorum-Sensing Activity of Tryptophan-Containing Cyclic Dipeptides." Marine Drugs 20, no. 2 (January 19, 2022): 85. http://dx.doi.org/10.3390/md20020085.

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Quorum sensing (QS) can regulate the pathogenicity of bacteria and the production of some virulence factors. It is a promising target for screening to find anti-virulence agents in the coming post-antibiotics era. Cyclo (L-Trp-L-Ser), one variety of cyclic dipeptides (CDPs), isolated from a marine bacterium Rheinheimera aquimaris, exhibited anti-QS activity against Chromobacterium violaceum CV026 and Pseudomonas aeruginosa PAO1. Unlike the CDPs composed of phenylalanine or tyrosine, the anti-QS activity has been widely studied; however, cyclo (L-Trp-L-Ser) and derivatives, containing one tryptophan unit and one non-aromatic amino acid, have not been systematically explored. Herein, the cyclo (L-Trp-L-Ser) and seven derivatives were synthesized and evaluated. All tryptophane-contained CDPs were able to decrease the production of violacein in C.violaceum CV026 and predicted as binding within the same pocket of receptor protein CviR, but in lower binding energy compared with the natural ligand C6HSL. As for P. aeruginosa PAO1, owning more complicated QS systems, these CDPs also exhibited inhibitory effects on pyocyanin production, swimming motility, biofilm formation, and adhesion. These investigations suggested a promising way to keep the tryptophan untouched and make modifications on the non-aromatic unit to increase the anti-QS activity and decrease the cytotoxicity, thus developing a novel CDP-based anti-virulence agent.

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21

Laurans, Ludivine, and Soraya Taleb. "Métabolisme du tryptophane et interactions avec le microbiote intestinal." Cahiers de Nutrition et de Diététique 56, no. 3 (June 2021): 154–61. http://dx.doi.org/10.1016/j.cnd.2021.01.001.

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22

Dell'Isola, B., N. Rezgui, J. M. Thiollieres, J. Labrousse, J. Lissac, and J. Cl Valcke. "Pleuro-péricardite aiguë avec éosinophilie après ingestion de tryptophane." La Revue de Médecine Interne 14, no. 5 (May 1993): 353–54. http://dx.doi.org/10.1016/s0248-8663(05)81317-7.

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23

Rahim, Barham Kamal, Fahmi F. Muhammadsharif, Salah Raza Saeed, and Kamal Aziz Ketuly. "Spectroscopic properties and optoelectronic parameters of ternary composites incorporating poly(L-Tryptophane):P(TER-CO-TRI) and Sudan dye." Journal of Physics: Theories and Applications 7, no. 1 (March 27, 2023): 1. http://dx.doi.org/10.20961/jphystheor-appl.v7i1.64418.

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<p>In this study, the spectroscopic properties and optoelectronic parameters of a ternary composite containing poly(L-Tryptophane): P(TER-CO-TRI) and Sudan dye were thoroughly investigated. Poly(L-Tryptophane) and P (TER-CO-TRI), the electron acceptor and donor, were solution processed and doped with different ratios of Sudan dye to form ternary composite systems. The FTIR technique, UV-Vis spectroscopy, and cyclic voltammetry (CV) were utilized to study the broad properties of the samples. Results showed that with the help of dye doping, the non-dispersive refractive index and energy gap of the ternary system were increased to 2.00 and decreased to 2.11 eV, respectively. The optical band gap, refractive index, dielectric constant, and optical conductivity of the samples were elaborated. The nature of the electronic transition in the studied samples was found to be a direct allowed transition, which was derived from the application of Tauc’s equation. The combination of CV test and absorption spectroscopy was successfully used to determine the molecular energy levels, HOMO and LUMO of the polymer samples.</p>

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24

FUJII, Isao. "Crystal Structure of L-(S)-Tryptophane D-(R)-mandelate 1.5H2O." X-ray Structure Analysis Online 25 (2009): 35–36. http://dx.doi.org/10.2116/xraystruct.25.35.

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25

Roussel, Virginie, Sophie Tardieu, Joëlle Micallef, and Olivier Blin. "Le test de déplétion en tryptophane : aspects méthodologiques et pratiques." Therapies 58, no. 4 (July 2003): 295–303. http://dx.doi.org/10.2515/therapie:2003046.

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26

Oltenfreiter, Ruth, Ludovicus Staelens, Soraya Labied, Veerle Kersemans, Francis Frankenne, Agnes Noël, Christophe Van de Wiele, and Guido Slegers. "Tryptophane-Based Biphenylsulfonamide Matrix Metalloproteinase Inhibitors as Tumor Imaging Agents." Cancer Biotherapy and Radiopharmaceuticals 20, no. 6 (December 2005): 639–47. http://dx.doi.org/10.1089/cbr.2005.20.639.

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27

Hong, Eun Young, and Nam Joo Hong. "Combined Role of Two Tryptophane Residues of α-Factor Pheromone." Bulletin of the Korean Chemical Society 34, no. 2 (February 20, 2013): 600–608. http://dx.doi.org/10.5012/bkcs.2013.34.2.600.

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28

Agus, Allison, and Harry Sokol. "Tryptophane et dérégulations métaboliques, un nouvel enjeu pour la santé." médecine/sciences 35, no. 3 (March 2019): 213–15. http://dx.doi.org/10.1051/medsci/2019040.

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29

Zhukovskii, A. P., V. M. Bakulev, M. A. Zhukovskii, and N. V. Rovnov. "Fluorescence study of the state of tryptophane in aqueous dimethylsulfoxide." Journal of Structural Chemistry 38, no. 1 (January 1997): 78–82. http://dx.doi.org/10.1007/bf02768810.

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30

Miri, Andressa L., Andressa P. Hosni, Jossinelma C. Gomes, Rubiana M. Mainardes, Najeh M. Khalil, Rossana G. del J.V. Marcano, Mário C. da S. Pereira, and Ivo I. Kerppers. "Study of the Effects of L-tryptophane Nanoparticles on Motor Behavior in Alzheimer's Experimental Models." CNS & Neurological Disorders - Drug Targets 18, no. 1 (February 21, 2019): 44–51. http://dx.doi.org/10.2174/1871527317666181105111157.

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Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by the progressive and incapacitating decay of cognitive, neuropsychiatric, and behavioral manifestations. L-tryptophan is the precursor amino acid of serotonin, which is a neurotransmitter responsible for mood balance and the sense of well-being and can be administered in the form of nanoparticles. Objective: This study analyzed the effectiveness of L-tryptophan nanoparticles and L-tryptophan on behavioral physiological alterations resulting from AD in animal models. Methods: The sample consisted of 50 Rattus norvegicus rats, divided in 10 groups with 5 animals each: one negative control (NC), three positive control groups (C3, C7, and C21), three groups treated with L-tryptophan nanoparticles (T3N, T7N, and T21N) at the concentration of 1.5 mg, and three groups treated with L-tryptophan (T3L, T7L, and T21L) at the concentration of 1.5 mg. The rats underwent stereotactic surgery to induce AD through the injection of amyloid beta-amyloid peptide1-42 in the intracerebroventricular region. All rats were submitted to pre- and post-surgery and post-treatment motor behavior evaluation through the Later Water Maze (LWM) and elevated cross-labyrinth (ECL). Histological analysis was performed to verify the presence of senile plaques, and the statistical analysis used the unpaired T-test. Results: Significant intergroup differences were observed in some of the evaluated parameters between treated and untreated groups. Conclusion: It was concluded that the treatment with L-tryptophan nanoparticles was beneficial to improve behavioral reactions in the Alzheimer's model.

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31

Ohlendorf, Birgit, Sven Simon, Jutta Wiese, and Johannes F. Imhoff. "Szentiamide, an N-formylated Cyclic Depsipeptide from Xenorhabdus szentirmaii DSM 16338T." Natural Product Communications 6, no. 9 (September 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600909.

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Szentiamide (1) a new cyclic hexadepsipeptide was isolated from the culture broth of the entomopathogenic bacterium Xenorhabdus szentirmaii DSM 16338T. The structure was elucidated by analysis of one- and two-dimensional NMR spectra and high resolution mass spectrometry. The amino acids were determined to be D-leucine, L-threonine, D-phenylalanine, D-valine, L-tyrosine and L-tryptophane after hydrolysis and derivatization with D-FDVA [ Nα-(2,4-dinitro-5-fluorophenyl)-D-valinamide].

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32

Chang, Shyi-Feu, James W. Ayres, and William E. Sandine. "Analysis of Cheese for Histamine, Tyramine, Tryptamine, Histidine, Tyrosine, and Tryptophane." Journal of Dairy Science 68, no. 11 (November 1985): 2840–46. http://dx.doi.org/10.3168/jds.s0022-0302(85)81176-0.

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33

Lepère, V., B. Lucas, M. Barat, J. A. Fayeton, Y. J. Picard, C. Jouvet, P. Çarçabal, et al. "Characterization of neutral fragments issued from the photodissociation of protonated tryptophane." Physical Chemistry Chemical Physics 9, no. 39 (2007): 5330. http://dx.doi.org/10.1039/b708814k.

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34

Fendler, Karoline, Beate Hager, and Heinz Falk. "The Thermal Diastereomerization of the Tryptophane-Derived Green Fluorescent Protein Chromophore." Monatshefte für Chemie - Chemical Monthly 138, no. 9 (July 20, 2007): 859–62. http://dx.doi.org/10.1007/s00706-007-0738-7.

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35

Chen, Qiao, Juan Zhou, Qian Han, Yonghua Wang, and Yingzi Fu. "Electrochemical enantioselective recognition of tryptophane enantiomers based on chiral ligand exchange." Colloids and Surfaces B: Biointerfaces 92 (April 2012): 130–35. http://dx.doi.org/10.1016/j.colsurfb.2011.11.031.

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36

Lazar, E., E. Vicenzi, E. Van Obberghen-Schilling, B. Wolff, S. Dalton, S. Watanabe, and M. B. Sporn. "Transforming growth factor alpha: an aromatic side chain at position 38 is essential for biological activity." Molecular and Cellular Biology 9, no. 2 (February 1989): 860–64. http://dx.doi.org/10.1128/mcb.9.2.860-864.1989.

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Site-directed mutagenesis has been performed in the human transforming growth factor alpha gene. When tyrosine 38 is mutated into phenylalanine or tryptophane, biological activity is retained. In contrast, other alterations between cysteine 34 and cysteine 43 and disruption of disulfide bonds 8 to 21 and 34 to 43 resulted in loss of activities. The presence of an aromatic side chain at position 38 of transforming growth factor alpha seems to be essential for its activity.

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37

Lazar, E., E. Vicenzi, E. Van Obberghen-Schilling, B. Wolff, S. Dalton, S. Watanabe, and M. B. Sporn. "Transforming growth factor alpha: an aromatic side chain at position 38 is essential for biological activity." Molecular and Cellular Biology 9, no. 2 (February 1989): 860–64. http://dx.doi.org/10.1128/mcb.9.2.860.

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Site-directed mutagenesis has been performed in the human transforming growth factor alpha gene. When tyrosine 38 is mutated into phenylalanine or tryptophane, biological activity is retained. In contrast, other alterations between cysteine 34 and cysteine 43 and disruption of disulfide bonds 8 to 21 and 34 to 43 resulted in loss of activities. The presence of an aromatic side chain at position 38 of transforming growth factor alpha seems to be essential for its activity.

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38

Kadim, E. M., and A. A. Alhamdani. "Study Reactive Effects of Lighting Systems and Addition Melatonin and L - Tryptophane on Heat Shock Proteins (HSP70), Melatonin and The Antioxidant Status in Broiler Chicken Managed in Hot Climates." IOP Conference Series: Earth and Environmental Science 1252, no. 1 (December 1, 2023): 012110. http://dx.doi.org/10.1088/1755-1315/1252/1/012110.

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Abstract The study examined how lighting system, feed additive, or their synergy reduces the negative effects of hot climates on broiler chicks in Iraq. Two light programs were tested. CLP is the first program, with 23 hours of light and one hour of scotoperiod. The second program, Intermittent Lighting Program (ILP), consisted of 9 hours’ photoperiod, 3 hours scotoperiod, and 4 nutritive treatments. T1 (Control). T2 adds 0.50 mg/kg/ration melatonin. T3 adds 400 mg/kg/ration tryptophane. T4 adds 400 mg/kg tryptophane and cofactors. 240 one-day-old male Ross 308 chicks with a mean body weight of 47 gm were managed until day 7 of the experiment. Three replicates of 10 chicks were randomly assigned to 8 treatments. The experiment lasted 49 days. ILP improved (P < 0.05) in heat shock proteins. HSP70 vs. CLP T2, T3, and T4 improved significantly from T1. ILP also benefits from feed additive interaction. The interaction between feed additive and lighting program showed that T2 in CLP and T3 in ILP improved significantly (P < 0.05) compared to T1, T3, and T4 of CLP and T1 and T2 of ILP, but not T4. In conclusion, intermittent lighting with or without nutritional additives mitigated the negative effects of hot climates on broilers’ antioxidant status and HSP70 levels.

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39

Al-Jumaily, Essam F., and Najwa S. A. Al-Samaraai. "Optimal conditions for production of Indole Acetic Acid (IAA) from local Fusarium oxysporum F2." Journal of Biotechnology Research Center 3, no. 1 (January 1, 2009): 15–22. http://dx.doi.org/10.24126/jobrc.2009.3.1.35.

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The isolate Fusarium oxysporum F2 was selected based on its high production of growth regulator IAA and used in the present study .The optimal condition for the production of Plant hormone (IAA) by using cultural medium composed of 4.5% sucrose, 0.6% Yeast extract, 0.3g KH2PO4 , 0.05g MgSO4 , 3mM Tryptophane and optimum inocula size was 1×106 spore/ ml and the initial pH was 8.5 the incubation period was 10 day at 28 Co in dark by using shaker incubator at 120 rpm.

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Garcia, Edivaldo E., Cláudia C. M. Kimura, Ariovaldo C. Martins, Gisele O. Rocha, and Jorge Nozaki. "Chromatographic characterization of products isolated from chrome shavings." Brazilian Archives of Biology and Technology 42, no. 3 (1999): 281–90. http://dx.doi.org/10.1590/s1516-89131999000300003.

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Gel permeation chromatography and high performance liquid chromatography were employed for separation and chemical characterization of products isolated from chrome shavings. After enzymatic hydrolysis, the products isolated were peptides of higher molecular weight. Peptides of lower molecular weight and free aminoacids were the main products using sulfuric acid in chrome shavings solubilization. Glycine (17%) , glutamic acid (10.6%) , alanine (9.2%) , and arginine (8.2%) were the principal amino acids found. Phenylalanine(1.8%) was the main aromatic amino acid , while tryptophane was completely absent.

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Weyssenhoff, H. v., H. L. Selzle, and E. W. Schlag. "Laser-Desorbed Large Molecules in a Supersonic Jet." Zeitschrift für Naturforschung A 40, no. 7 (July 1, 1985): 674–76. http://dx.doi.org/10.1515/zna-1985-0703.

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A new technique of desorption of non volatile thermally unstable molecules into a supersonic jet has been developped. With this method isolated large molecules are now available for mass spectrometry as well as for spectroscopic studies at temperatures of a few Kelvin, thus avoiding spectral congestion. It could be demonstrated that molecules like tryptophane and retinal could be desorbed with an IR laser pulse without decomposition and be ionized with a second UV laser to form bare molecule ions without fragmentation.

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Blech, St, and H. Budzikiewicz. "β-Carboline Alkaloids from Ribes nigrum L." Zeitschrift für Naturforschung C 49, no. 9-10 (October 1, 1994): 540–44. http://dx.doi.org/10.1515/znc-1994-9-1002.

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Abstract From Ribes nigrum L. two β-carboline alkaloids (deshydroxymethyl flazin (1) and flazin methyl ether (2)) could be isolated in minute amounts. The structure elucidation is described. The two compounds are present in the freshly pressed juice, but they are also formed during storage of the juice by condensation of tryptophane with ascorbic acid or its degradation products. This could be shown by adding 14C-labelled ascorbic acid to the juice. After four weeks’ incubation radioactive 1 and 2 could be isolated.

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LIU, YANG SHENG, YOU YUAN DAI, and JIA DING WANG. "Distribution Behavior ofL-Tryptophane by Extraction with Di(2-ethylhexyl) Phosphoric Acid." Separation Science and Technology 35, no. 9 (January 9, 2000): 1439–54. http://dx.doi.org/10.1081/ss-100100234.

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44

Lee, Jae-Wook, Thi Phuong Binh Nguyen, and Hee Moon. "Adsorption and desorption of phenylalanine and tryptophane on a nonionic polymeric sorbent." Korean Journal of Chemical Engineering 23, no. 5 (September 2006): 812–18. http://dx.doi.org/10.1007/bf02705933.

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45

Węgiel, Janina, and Stanisław Kohlmünzer. "Aleuria aurantia - indole metabolites of fruit bodies, mycelial culture and culture medium." Acta Mycologica 35, no. 2 (August 20, 2014): 331–37. http://dx.doi.org/10.5586/am.2000.031.

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The aim of present study was to investigate and compare indole metabolites of fruit bodies, mycelium cultivated <i>in vitro</i> and culture medium of the fungus <i>Aleuria aurantia</i> (Fr.) Fuck. By use of a number of chromatographic and spectroscopic methods several indole metabolites have been detected and identified among other the 3-indolebutyric acid was produced and extracted to the culture medium. Furthermore 3-indoleatonitrile and tryptophane degradative products have been found both in fruit bodies and mycelium.

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46

Evseev, A. "Meal Patterns for Vegetarians." Bulletin of Science and Practice, no. 10 (October 15, 2022): 196–202. http://dx.doi.org/10.33619/2414-2948/83/25.

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Presented in the paper are three eating patterns for various types of vegetarians. Meal pattern no. 1 stresses the vitality of the replacement of the lack of vitamins and minerals associated with the strict vegan diet. Meal pattern no. 2 emphasizes the inclusion of foods to reduce the level of low-density lipoprotein (LDL) in the daily lacto-vegetarian diet. As well as that meal pattern no. 2 increases methionine and tryptophane in human blood. Meal pattern no. 3 intended for lacto-ovo-vegetarians is a balanced diet dominated by complex carbohydrates and an increased level of antioxidants in the diet.

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Niehrs, Christof, and Jan Ahlers. "Pentachlorophenol Inhibits Photosynthetic Electron Flow and Quenches Chlorophyll Fluorescence after Preillumination." Zeitschrift für Naturforschung C 41, no. 4 (April 1, 1986): 433–36. http://dx.doi.org/10.1515/znc-1986-0410.

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The pesticide PCP was shown to inhibit the Hill reaction in broken chloroplasts (I50 = 15 μᴍ) and to quench chlorophyll fluorescence. Both effects require preillumination. In contrast to the common “phenol-type” inhibitors, neither inhibition of Hill reaction nor chlorophyll fluorescence quench were affected by pretreatment of chloroplast with trypsin instead of preillumination. An inhibition site differing from the “phenol type” inhibitors is therefore assumed. The results presented indicate that the observed light requirement is due to electron transport through PS II. Measurements of intrinsic tryptophane fluorescence relate the PCP site of binding to a hydro- phobic environment.

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48

Pirog, T. P., D. V. Piatetska, V. I. Zhdanyuk, N. O. Leonova, and T. A. Shevchuk. "Effect of Tryptophane on Synthesis of Certain Exometabolites by Bacteria of Genus Acinetobacter, Nocardia, and Rhodococcus and Their Properties." Mikrobiolohichnyi Zhurnal 84, no. 6 (February 28, 2023): 50–61. http://dx.doi.org/10.15407/microbiolj84.06.050.

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The efficiency of integrated microbial biotechnologies for obtaining several practically valuable metabolites in one technological process is determined both by the maximum concentration of these substances and their properties. This is especially true for secondary metabolites, the composition and properties of which vary depending on the cultivation conditions of the producer. Aim. To research the effect of tryptophan (a precursor of auxin biosynthesis) in the culture media on the synthesis of certain exometabolites by Rhodococcus erythropolis IMV Ac-5017, Acinetobacter calcoaceticus IMV B-7241, and Nocardia vaccinii IMV B-7405 as well as their properties. Methods. R. erythropolis IMV Ac-5017, A. calcoaceticus IMV B-724, and N. vaccinii IMV B-7405 were cultivated in a medium containing refined and waste sunflower oil, biodiesel waste, or ethanol as a carbon source. The concentration of tryptophan in the medium was 300 mg/L. Surfactants were extracted from the supernatant of the cultural liquid with a modified Folch mixture. Phytohormones were isolated from the supernatant by sequential extraction with organic solvents after surfactant extraction. Thin-layer chromatography was used for preliminary purification and concentration of phytohormones. Qualitative and quantitative determination of auxins was performed using high-performance liquid chromatography. The antimicrobial activity of surfactants was analysed by the minimum inhibitory concentration. The activity of enzymes of surface-active glycoand aminolipids biosynthesis (phosphoenolpyruvate synthetase, phosphoenolcarboxykinase, and NADP+-dependent glutamate dehydrogenase) was determined spectrophotometrically during the oxidation of NADH or NADP. Results. It was found that the presence of tryptophan in the culture medium of the strains under study did not affect the number of synthesized surfactants, which was 1.80−1.90, 1.55−1.75, and 1.50−1.65 g/L, respectively. At the same time, cultivation of R. erythropolis IMV Ac-5017, A. calcoaceticus IMV B-724, and N. vaccinii IMV B-7405 in the media with tryptophan increased the number of phytohormones: it was higher than the amount of phytohormones synthesized during cultivation without a precursor. The introduction of tryptophan into the culture medium of the strains was accompanied by the formation of surfactants. These compounds showed 2−4 times higher antimicrobial activity against the phytopathogenic bacteria (Agrobacterium tumefaciens UCM B-1000, Pseudomonas syringae UCM B-1027T, Xanthomonas vesicatoria UCM B-1106, Pectobacterium carotovorum UCM B-1075T, Clavibacter michiganensis IMV B-102 and Pseudomonas syringae pv. tomato IMV B-9167) than compounds synthesized on a medium without a precursor. The antimicrobial activity of surfactants synthesized by A. calcoaceticus IMV B-7241 in the presence of tryptophan either did not change compared to that for surfactants obtained without tryptophan, or increased slightly. Data on the activity of surfactant biosynthesis enzymes correlated with the indicators of their antimicrobial activity. In the presence of tryptophan in the culture medium of N. vaccinii IMV B-7405 and R. erythropolis IMV Ac-5017, NADP+-dependent glutamate dehydrogenase activity in the cells of these strains (a key enzyme for biosynthesis of aminolipids responsible for antimicrobial activity) increased almost by 1.4 times compared to that on a tryptophan-free medium. Conclusions. As a result of this work, it was found that the presence of tryptophan in the culture medium of researched strains did not affect the number of surfactants. The antimicrobial activity of surfactants against phytopathogenic bacteria either increased or remained unchanged compared to that established for surfactants synthesized without a precursor of auxin biosynthesis. The obtained data testify to the high efficiency of the potential use of surfactants complex preparations and phytohormones in crop production to stimulate the growth of plants and biocontrol of phytopathogenic bacteria.

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Richard, Dawn M., Michael A. Dawes, Charles W. Mathias, Ashley Acheson, Nathalie Hill-Kapturczak, and Donald M. Dougherty. "L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications." International Journal of Tryptophan Research 2 (January 2009): IJTR.S2129. http://dx.doi.org/10.4137/ijtr.s2129.

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An essential component of the human diet, L-tryptophan is critical in a number of metabolic functions and has been widely used in numerous research and clinical trials. This review provides a brief overview of the role of L-tryptophan in protein synthesis and a number of other metabolic functions. With emphasis on L-tryptophan's role in synthesis of brain serotonin, details are provided on the research uses of L-tryptophan, particularly L-tryptophan depletion, and on clinical trials that have been conducted using L-tryptophan supplementation. The ability to change the rates of serotonin synthesis in the brain by manipulating concentrations of serum tryptophan is the foundation of much research. As the sole precursor of serotonin, experimental research has shown that L-tryptophan's role in brain serotonin synthesis is an important factor involved in mood, behavior, and cognition. Furthermore, clinical trials have provided some initial evidence of L-tryptophan's efficacy for treatment of psychiatric disorders, particularly when used in combination with other therapeutic agents.

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Matsuura, Kazunori, Kazuya Murasato, and Nobuo Kimizuka. "Syntheses and Self-assembling Behaviors of Pentagonal Conjugates of Tryptophane Zipper-Forming Peptide." International Journal of Molecular Sciences 12, no. 8 (August 15, 2011): 5187–99. http://dx.doi.org/10.3390/ijms12085187.

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