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1

Chandanani, Mehak, Raian Jaibaji, Monketh Jaibaji, and Andrea Volpin. "Tibial Spine Avulsion Fractures in Paediatric Patients: A Systematic Review and Meta-Analysis of Surgical Management." Children 11, no. 3 (2024): 345. http://dx.doi.org/10.3390/children11030345.

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Background: Tibial spine avulsion fractures (TSAFs) account for approximately 14% of anterior cruciate ligament injuries. This study aims to systematically review the current evidence for the operative management of paediatric TSAFs. Methods: A search was carried out across four databases: MEDLINE, Embase, Scopus, and Google Scholar. Studies discussing the outcomes of the surgical management of paediatric TSAFs since 2000 were included. Results: Of 38 studies included for review, 13 studies reported outcomes of TSAF patients undergoing screw fixation only, and 12 studies used suture fixation o
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Streit, Katharina, and Yosef Garfinkel. "Tel Tsaf and the Impact of the Ubaid Culture on the Southern Levant: Interpreting the Radiocarbon Evidence." Radiocarbon 57, no. 5 (2015): 865–80. http://dx.doi.org/10.2458/azu_rc.57.18200.

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A data set of 18 radiocarbon dates from the domestic quarter and the well at Tel Tsaf provide conclusive evidence for the absolute dating of this Middle Chalcolithic site. Bayesian modeling suggests that the site was occupied in the last quarter of the 6th millennium BC and abandoned in the first quarter of the 5th millennium. The absolute dating of Tel Tsaf has further implications for the synchronization of the protohistory of the Levant. The ceramic assemblage of Tel Tsaf included delicately painted ceramic sherds (so-called Tel Tsaf ware), which are distinct from the common plain ware. Com
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Palmeter, Sarah, Adam Probert, and Claudia Lagacé. "Prévalence du trouble du spectre de l’alcoolisation fœtale (TSAF) chez les enfants et les adolescents : résultats de l’Enquête canadienne sur la santé des enfants et des jeunes de 2019." Promotion de la santé et prévention des maladies chroniques au Canada 41, no. 9 (2021): 300–304. http://dx.doi.org/10.24095/hpcdp.41.9.05f.

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Introduction L’absence d’estimations de la prévalence nationale du trouble du spectre de l’alcoolisation fœtale (TSAF) constitue une lacune importante dans les connaissances. Méthodologie La prévalence du TSAF, déterminée à l’aide des données de l’Enquête canadienne sur la santé des enfants et des jeunes de 2019, a été analysée en fonction de l’âge, du sexe et de l’identité (autochtone ou non autochtone). L’âge médian au moment du diagnostic et les problèmes de santé concomitants de longue durée ont aussi été examinés. Résultats La prévalence du TSAF chez les enfants et les adolescents canadie
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MAMPEL, Jörg, Elke MAIER, Tewes TRALAU, Jürgen RUFF, Roland BENZ, and Alasdair M. COOK. "A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2." Biochemical Journal 383, no. 1 (2004): 91–99. http://dx.doi.org/10.1042/bj20040652.

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Inducible mineralization of TSA (4-toluenesulphonate) by Comamonas testosteroni T-2 is initiated by a secondary transport system, followed by oxygenation and oxidation by TsaMBCD to 4-sulphobenzoate under the regulation of TsaR and TsaQ. Evidence is presented for a novel, presumably two-component transport system (TsaST). It is proposed that TsaT, an outer-membrane porin, formed an anion-selective channel that works in co-operation with the putative secondary transporter, TsaS, located in the inner membrane. tsaT was identified as a 1017-bp ORF (open reading frame) on plasmid pTSA upstream of
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Hellwing, Salo Shlomo. "Animal Bones from Tel Tsaf." Tel Aviv 15, no. 1 (1988): 47–51. http://dx.doi.org/10.1179/tav.1988.1988.1.47.

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Horowitz, Aharon. "Pollen Analysis from Tel Tsaf." Tel Aviv 15, no. 1 (1988): 55. http://dx.doi.org/10.1179/tav.1988.1988.1.55.

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7

Gopher, Avi. "The Flint Industry from Tel Tsaf." Tel Aviv 15, no. 1 (1988): 37–46. http://dx.doi.org/10.1179/tav.1988.1988.1.37.

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8

Rosenberg, Danny, Jacqueline Meier, Yaakov Weiss, et al. "The Characteristics of the Earliest Levels of Tel Tsaf and the Onset of the Middle Chalcolithic Period in the Jordan Valley, Israel." Jerusalem Journal of Archaeology 8 (2025): 1–40. https://doi.org/10.52486/01.00008.1.

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Of the various chrono-stratigraphic entities of the Chalcolithic period in the southern Levant, the Middle Chalcolithic period (ca. 5300–4700 BCE) is the most poorly defined, with most of the relevant data coming from Tel Tsaf. While excavations at Tel Tsaf in the last two decades provide valuable information concerning the site’s upper occupational levels, the earlier strata and their material culture are still unknown. Past excavations focused on the later stage of the site’s occupation, leaving unanswered questions concerning the transition from the Early to the Middle Chalcolithic period.
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Freikman, Michael, David Ben-Shlomo, and Yosef Garfinkel. "The “Violin-Shaped” Figurines of Tel Tsaf." Paléorient, no. 47-2 (November 1, 2021): 43–59. http://dx.doi.org/10.4000/paleorient.1287.

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10

Liphschitz, Nili. "Analysis of the Botanical Remains from Tel Tsaf." Tel Aviv 15, no. 1 (1988): 52–54. http://dx.doi.org/10.1179/tav.1988.1988.1.52.

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11

Garfınkel, Yosef, David Ben-Shlomo, and Tali Kuperman. "Large-scale storage of grain surplus in the sixth millennium BC: the silos of Tel Tsaf." Antiquity 83, no. 320 (2009): 309–25. http://dx.doi.org/10.1017/s0003598x00098458.

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AbstractThe authors report and describe the remarkable grain silos discovered at Tel Tsaf in the southern Levant. These tall, white, barrel-shaped towers seem to mark the first appearance of monuments of demonstrative surplus.
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12

Luthra, Amit, Naduni Paranagama, William Swinehart, et al. "Conformational communication mediates the reset step in t6A biosynthesis." Nucleic Acids Research 47, no. 12 (2019): 6551–67. http://dx.doi.org/10.1093/nar/gkz439.

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Abstract The universally conserved N6-threonylcarbamoyladenosine (t6A) modification of tRNA is essential for translational fidelity. In bacteria, t6A biosynthesis starts with the TsaC/TsaC2-catalyzed synthesis of the intermediate threonylcarbamoyl adenylate (TC–AMP), followed by transfer of the threonylcarbamoyl (TC) moiety to adenine-37 of tRNA by the TC-transfer complex comprised of TsaB, TsaD and TsaE subunits and possessing an ATPase activity required for multi-turnover of the t6A cycle. We report a 2.5-Å crystal structure of the T. maritima TC-transfer complex (TmTsaB2D2E2) bound to Mg2+-
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13

Su, Chenchen, Mengqi Jin, and Wenhua Zhang. "Conservation and Diversification of tRNA t6A-Modifying Enzymes across the Three Domains of Life." International Journal of Molecular Sciences 23, no. 21 (2022): 13600. http://dx.doi.org/10.3390/ijms232113600.

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The universal N6-threonylcarbamoyladenosine (t6A) modification occurs at position 37 of tRNAs that decipher codons starting with adenosine. Mechanistically, t6A stabilizes structural configurations of the anticodon stem loop, promotes anticodon–codon pairing and safeguards the translational fidelity. The biosynthesis of tRNA t6A is co-catalyzed by two universally conserved protein families of TsaC/Sua5 (COG0009) and TsaD/Kae1/Qri7 (COG0533). Enzymatically, TsaC/Sua5 protein utilizes the substrates of L-threonine, HCO3−/CO2 and ATP to synthesize an intermediate L-threonylcarbamoyladenylate, of
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14

O'Donnell, Siobhan, Sarah Palmeter, Meghan Laverty, and Claudia Lagacé. "Exactitude des algorithmes des bases de données administratives pour la détermination des cas de trouble du spectre de l’autisme, de trouble du déficit de l’attention/hyperactivité et de trouble du spectre de l’alcoolisation fœtale : revue systématique." Promotion de la santé et prévention des maladies chroniques au Canada 42, no. 9 (2022): 401–33. http://dx.doi.org/10.24095/hpcdp.42.9.01f.

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Introduction L'objectif de cette revue systématique était d'évaluer la validité des algorithmes des bases de données administratives utilisés pour repérer les cas de trouble du spectre de l'autisme (TSA), de trouble du déficit de l'attention/hyperactivité (TDAH) et de trouble du spectre de l'alcoolisation fœtale (TSAF). Méthodologie L'équipe de recherche a interrogé les systèmes MEDLINE, Embase, Global Health et PsycInfo afin de trouver des études, publiées en anglais ou en français entre 1995 et 2021, qui valident des algorithmes servant à recenser les cas de TSA, de TDAH et de TSAF dans les
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15

Gophna, Ram, and Shelley Sadeh. "Excavations at Tel Tsaf: An Early Chalcolithic Site in the Jordan Valley." Tel Aviv 15, no. 1 (1988): 3–36. http://dx.doi.org/10.1179/tav.1988.1988.1.3.

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16

Graham, Philip. "Archaeobotanical remains from late 6th/early 5th millennium BC Tel Tsaf, Israel." Journal of Archaeological Science 43 (March 2014): 105–10. http://dx.doi.org/10.1016/j.jas.2013.12.018.

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17

Hruby, Karolina, Florian Klimscha, and Danny Rosenberg. "The Tel Tsaf decoration: Contextualizing a Chalcolithic pottery phenomenon on a regional scale." Archaeological Research in Asia 40 (December 2024): 100541. http://dx.doi.org/10.1016/j.ara.2024.100541.

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18

Bhisama, Ida Bagus Prastha, Made Sukrawa, and Ida Ayu Made Budiwati. "ANALISIS PERILAKU THREE-SIDED ARCH SEBAGAI ALTERNATIF DARI BOX CULVERT." JURNAL SPEKTRAN 9, no. 1 (2021): 12. http://dx.doi.org/10.24843/spektran.2021.v09.i01.p02.

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Penelitian ini dilakukan untuk mengetahui perilaku dari struktur three-sided arch (TSA) yang merupakan salah satu alternatif dari struktur box culvert (BC). Perilaku kedua struktur dibandingkan melalui pemodelan elemen hingga pada program SAP2000. Pemodelan model validasi merupakan tahap awal dalam penelitian ini, yang dibuat berdasarkan pada hasil uji laboratorium oleh peneliti lain. Hasil pemodelan validasi menunjukkan bahwa pemodelan dengan elemen frame (MFR) dan shell (MSH) lebih mendekati hasil uji laboratorium, sedangkan elemen solid (MSO) jauh berbeda sehingga tidak digunakan dalam mode
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19

Rosenberg, Danny, Yael Elkayam, Yossi Garfinkel, Florian Klimscha, Vesna Vučković, and Yaakov Weiss. "Long-distance trade in the Middle Chalcolithic of the southern Levant: The case of the olivine beads from Tel Tsaf, Jordan Valley, Israel." PLOS ONE 17, no. 8 (2022): e0271547. http://dx.doi.org/10.1371/journal.pone.0271547.

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Eight olivine beads found at the Middle Chalcolithic site of Tel Tsaf (ca. 5,200–4,700 cal. BC), Jordan Valley, Israel, underscore a new facet of interregional exchange for this period. The current paper presents the olivine beads assemblage, its morphometric and technological characteristics, and chemical composition. The results of the chemical analysis suggest that all eight beads derive from the same source. By means of comparison with the chemical characteristics of known olivine sources, we argue for a northeastern African–western Arabian provenience and cautiously suggest Ethiopia as a
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20

Streit, Katharina, and Yosef Garfinkel. "A Specialized Ceramic Assemblage for Water Pulling: The Middle Chalcolithic Well of Tel Tsaf, Israel." Bulletin of the American Schools of Oriental Research 374 (November 2015): 61–73. http://dx.doi.org/10.5615/bullamerschoorie.374.0061.

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Rosenberg, Danny, Serena Love, Emily Hubbard, and Florian Klimscha. "7,200 years old constructions and mudbrick technology: The evidence from Tel Tsaf, Jordan Valley, Israel." PLOS ONE 15, no. 1 (2020): e0227288. http://dx.doi.org/10.1371/journal.pone.0227288.

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22

Hubbard, Emily M. "Livestock and people in a Middle Chalcolithic settlement: a micromorphological investigation from Tel Tsaf, Israel." Antiquity 84, no. 326 (2010): 1123–34. http://dx.doi.org/10.1017/s0003598x00067120.

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Round and rectangular buildings with grain silos at a Copper Age site in Israel suggested social stratification to the excavators. Using micromorphology, the author demonstrates that while the rectangular building was occupied by people, the round ones had contained animals, perhaps as providers of milk, and dung for fuel. While this removes the direct indication of social variance, it strengthens the argument that animals, as well as grain, formed the basis for the creation of surplus.
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23

Dag, Doron, and Yosef Garfinkel. "The Flint Industry of Tel Tsaf, A Middle Chalcolithic Site in The Jordan Valley, Israel." Journal of the Israel Prehistoric Society 37 (2007): 381. https://doi.org/10.61247/s889637.

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24

Rosenberg, Danny, Florian Klimscha, Philip J. Graham, et al. "Back to Tel Tsaf: A Preliminary Report on The 2013 Season of the Renewed Project." Journal of the Israel Prehistoric Society 44 (2014): 148. https://doi.org/10.61247/s689106.

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25

Bekker, Marina, and Yosef Garfinkel. "Stone Pedestalled vessels from Tel Tsaf, a Middle Chalcolithic Site in the Central Jordan Valley, Israel." Journal of Lithic Studies 3, no. 3 (2016): 17. http://dx.doi.org/10.2218/jls.v3i3.1654.

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26

Horn, Christian, Florian Klimscha, and Danny Rosenberg. "Exploring the dimensions of Chalcolithic settlements in the southern Levant - A geomagnetic survey on Tel Tsaf, Israel." Journal of Archaeological Science: Reports 24 (April 2019): 380–90. http://dx.doi.org/10.1016/j.jasrep.2019.02.007.

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27

Rodríguez-Fernández, Alejandro, José Antonio Rodríguez-Marroyo, Javier Sánchez-Sánchez, Elba Díaz-Serradilla, José Gerardo Villa-Vicente, and Filipe Manuel Clemente. "Effects of short-term detraining in female football players: an approach based on initial level." Archivos de Medicina del Deporte 41, no. 5 (2025): 246–52. https://doi.org/10.18176/archmeddeporte.00181.

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Introduction: The main aim of this study was to examine the effects of detraining period based on the initial physical fitness level determined through the Total Score of Athleticism (TSA) in female soccer players. Material and method: Fourteen football players underwent pre- and post-detraining period (i.e., 2 weeks) assessments, which included a countermovement jump test (CMJ), a 30-meter sprint test, and a repeated sprint ability test (RSA: 8 sprints of 30 meters with 25 seconds of recovery). The players were classified based on TSA obtained before detraining period (TSAB = group of players
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Milevski, Ianir. "Yosef Garfinkel, David Ben-Shlomo and Michael Freikman (eds.). Excavations at Tel Tsaf 2004-2007: Final Report Volume 1 and Michael Freikman, David Ben-Shlomo and Yosef Garfinkel (eds.). Excavations at Tel Tsaf 2004-2007: Final Report Volume 2." Journal of the Israel Prehistoric Society 54 (2024): 233. https://doi.org/10.61247/s710899.

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Freikman, Michael, David Ben-Shlomo, and Yosef Garfinkel. "A stamped sealing from Middle Chalcolithic Tel Tsaf: implications for the rise of administrative practices in the Levant." Levant 53, no. 1 (2021): 1–12. http://dx.doi.org/10.1080/00758914.2021.1923906.

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30

Rosenberg, Danny, Yosef Garfinkel, and Florian Klimscha. "Large-scale storage and storage symbolism in the ancient Near East: a clay silo model from Tel Tsaf." Antiquity 91, no. 358 (2017): 885–900. http://dx.doi.org/10.15184/aqy.2017.75.

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Missoury, Sophia, Stéphane Plancqueel, Ines Li de la Sierra-Gallay, et al. "The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification." Nucleic Acids Research 46, no. 11 (2018): 5850–60. http://dx.doi.org/10.1093/nar/gky323.

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Missoury, Sophia, Stéphane Plancqueel, Ines Li de la Sierra-Gallay, et al. "The structure of the TsaB/TsaD/TsaE complex reveals an unexpected mechanism for the bacterial t6A tRNA-modification." Nucleic Acids Research 47, no. 17 (2019): 9464–65. http://dx.doi.org/10.1093/nar/gkz719.

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Chasan, Rivka, Florian Klimscha, Cynthianne Spiteri, and Danny Rosenberg. "Foodways of an agro-pastoral community: Organic residue analysis of pottery and stone vessels at Middle Chalcolithic Tel Tsaf." Journal of Archaeological Science: Reports 43 (June 2022): 103491. http://dx.doi.org/10.1016/j.jasrep.2022.103491.

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Garfinkel, Yosef, Florian Klimscha, Sariel Shalev, and Danny Rosenberg. "The Beginning of Metallurgy in the Southern Levant: A Late 6th Millennium CalBC Copper Awl from Tel Tsaf, Israel." PLoS ONE 9, no. 3 (2014): e92591. http://dx.doi.org/10.1371/journal.pone.0092591.

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Gessler, Arthur. "Editor’s highlight for TSAF D-17-00396: carbon and oxygen isotopes in tree rings—climate signals and microsite effects." Trees 32, no. 3 (2018): 881–82. http://dx.doi.org/10.1007/s00468-018-1681-4.

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Rosenberg, Danny, Sonia Pinsky, Karolina Hruby, and Florian Klimscha. "Tel Tsaf, a Middle Chalcolithic Site in The Jordan Valley: A Preliminary Report on The 2013–2022 Excavation Seasons." Journal of the Israel Prehistoric Society 53 (2023): 208. https://doi.org/10.61247/s766374.

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Rosenberg, Danny, Inbar Ktalav, Iris Groman-Yaroslvski, and Florian Klimscha. "Unique Theodoxus jordani shell beads from the Middle Chalcolithic site of Tel Tsaf (ca. 5200–4700 cal BC), Jordan Valley, Israel." Archaeological Research in Asia 29 (March 2022): 100349. http://dx.doi.org/10.1016/j.ara.2021.100349.

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Yakasai, Murtala Garba. "Nazarin Kurman Ɗa a Waƙar “Zuma” Ta Aminu Ladan Abubakar (ALA)." Tasambo Journal of Language, Literature, and Culture 3, no. 01 (2024): 215–23. http://dx.doi.org/10.36349/tjllc.2024.v03i01.024.

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Takardar ta yi nazarin waƙar baka ta ALA inda aka bibiyi amfani da ‘Kurman Ɗa’ wanda shi ne ya mamaye waƙar ‘zuma’ ta mawaƙin. An fahimci yadda ya yi amfani da hikima da azanci domin isar da saƙonsa ga masu nazari. ALA ya yi ta faman dibilwa ta amfani da harshen Hausa, wadda sai da manazarta suka ci kwakwa kafin fahimtar saƙon mawaƙin a cikin sauƙi. Dalilin wannan nazari domin masu sauraron waƙa da manazarta sun gaza yin caraf! Domin fahimtar saƙon da ke cikinta, sakamakon haka sai aka nazarce ta, aka fahimce ta, aka kuma tattauna da mawaƙin, sannan aka yi fashin baƙinta, domin fahimtar da ɗim
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Rosenberg, Danny, Li Liu, Maureece J. Levin, Florian Klimscha, and Dina Shalem. "From Hangovers to Hierarchies: Beer production and use during the Chalcolithic period of the southern Levant – New evidence from Tel Tsaf and Peqi‘in Cave." Journal of Anthropological Archaeology 64 (December 2021): 101361. http://dx.doi.org/10.1016/j.jaa.2021.101361.

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Chan, Benny K. K., Pei-Chen Tsai, and Yao-Feng Tsao. "A new intertidal barnacle, Chthamalus ngankeeae sp. nov. (Balanomorpha: Chthamalidae) from the Malaysian Peninsula and western Borneo waters." Zootaxa 5476, no. 1 (2024): 26–43. https://doi.org/10.11646/zootaxa.5476.1.6.

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Chan, Benny K. K., Tsai, Pei-Chen, Tsao, Yao-Feng (2024): A new intertidal barnacle, Chthamalus ngankeeae sp. nov. (Balanomorpha: Chthamalidae) from the Malaysian Peninsula and western Borneo waters. Zootaxa 5476 (1): 26-43, DOI: 10.11646/zootaxa.5476.1.6, URL: http://dx.doi.org/10.11646/zootaxa.5476.1.6
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Stec, Boguslaw. "Discovery of the Universal tRNA Binding Mode for the TsaD-like Components of the t6A tRNA Modification Pathway." Biophysica 3, no. 2 (2023): 288–306. http://dx.doi.org/10.3390/biophysica3020019.

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Covalent addition of the threonylcarbamoyl group to N(6) of adenosine 37 (t6A modification) within the anticodon loop of several tRNAs is central to the translational fidelity in all known organisms. Structures for each of the enzyme components in the Tsa (t6A) pathway from all three kingdoms of life have been determined previously. In order to shed light on the poorly defined final step of t6A tRNA modification by TsaD-like components, we performed modeling studies. By docking a tRNA substrate molecule onto reanalyzed complete models of three TsaD-like proteins—TsaD from T. maritima, Qri7 fro
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Iager, A. E., Z. Beyhan, P. J. Ross, et al. "37 EFFECTS OF TRICHOSTATIN A TREATMENT ON BOVINE SOMATIC CELL NUCLEAR TRANSFER EMBRYOS." Reproduction, Fertility and Development 20, no. 1 (2008): 99. http://dx.doi.org/10.1071/rdv20n1ab37.

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Faulty epigenetic reprogramming is a likely major cause of the low success rate observed in all mammals produced through somatic cell nuclear transfer (SCNT). It has been reported that treatment of reconstructed mouse embryos with the potent histone deacetylase inhibitor, trichostatin A (TSA), results in significantly increased developmental capacity of SCNT preimplantation embryos and live offspring (Kishigami et al. 2006 Biochem. Biophys. Res. Commun. 240, 183–189; Rybouchkin et al. 2006 Biol. Reprod. 74, 1083–1089; Kishigami et al. 2006 J. Reprod. Dev. 53, 165–170). Studies investigating si
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Russu, Octav Marius, Tudor Sorin Pop, Emilian Ciorcila, et al. "Arthroscopic Repair in Tibial Spine Avulsion Fractures Using Polyethylene Terephthalate Suture: Good to Excellent Results in Pediatric Patients." Journal of Personalized Medicine 11, no. 5 (2021): 434. http://dx.doi.org/10.3390/jpm11050434.

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Background: The objective of the arthroscopic treatment in tibial spine avulsion fractures (TSAF) is to achieve firm reduction and strong internal fixation while still having the patient undergo a minimally invasive procedure. Material and methods: The study was performed on 12 young patients with avulsion fracture of the anterior tibial spine. All 12 patients had type 3 Modified Meyers and McKeever fractures. The injury mechanism was direct anterior to posterior trauma in full leg length hyperextension with sport trauma reported in all cases. The physical examination revealed decreased range
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Sohail, Muhammad Amir, Amna Bashir, Mahnoor Amjad, Muhammad Bilal Afzal, and Javed Hassan Raza. "Comparison between Outcomes of Open and Arthroscopic Fixation of Tibial Spine Avulsion Fractures." Journal of Gandhara Medical and Dental Science 11, no. 2 (2024): 47–50. http://dx.doi.org/10.37762/jgmds.11-2.443.

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OBJECTIVES This study aimed to compare the functional outcomes of fragment reduction and to measure the rate of postoperative complications between arthrotomy (ORIF) and arthroscopy(ARIF) pediatric tibial spine avulsion fractures using the Lysholm knee scoring system (limp, pain swelling, climbing stairs) and IKDC subjective knee evaluation form. METHODS: This Comparative Study was conducted at the Department of Orthopedic Surgery, Jinnah Hospital Lahore, between 2021-2022. A total of 42 patients who had tibial spine avulsion fracture with follow-up of 6 months were included. Twenty-one patien
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Hamidi, Sepehr, Chun-Rong Chen, Ramachandran Murali, Sandra M. McLachlan, and Basil Rapoport. "Probing Structural Variability at the N Terminus of the TSH Receptor with a Murine Monoclonal Antibody That Distinguishes between Two Receptor Conformational Forms." Endocrinology 154, no. 1 (2013): 562–71. http://dx.doi.org/10.1210/en.2012-1822.

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Despite elucidation of the crystal structure of M22, a human thyroid-stimulating autoantibody (TSAb) bound to the TSH receptor (TSHR) leucine-rich repeat domain (LRD), the mechanism by which TSAs activate the TSHR and cause Graves’ disease remains unknown. A nonstimulatory murine monoclonal antibody, 3BD10, and TSAb interact with the LRD N-terminal cysteine cluster and reciprocally distinguish between two different LRD conformational forms. To study this remarkable phenomenon, we investigated properties of 3BD10, which has a linear epitopic component. By synthetic peptide ELISA, we identified
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46

Gutiérrez-Escobedo, Guadalupe, Oscar Hernández-Carreón, Brenda Morales-Rojano, et al. "Candida glabrata peroxiredoxins, Tsa1 and Tsa2, and sulfiredoxin, Srx1, protect against oxidative damage and are necessary for virulence." Fungal Genetics and Biology 135 (February 2020): 103287. http://dx.doi.org/10.1016/j.fgb.2019.103287.

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47

Arron Sonangnon, Brito Thibautéon, Aboudou Kowiou, Alidou Chérif, Goudjinou Codjo, and Soumanou M. Mohamed. "Analyse des pratiques de production et qualité des poissons fumés commercialisés au sud-Bénin." European Scientific Journal, ESJ 18, no. 17 (2022): 154. http://dx.doi.org/10.19044/esj.2022.v18n17p154.

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Cette étude vise à analyser les pratiques de production et évaluer la qualité des poissons fumés commercialisés au Sud-Bénin. A cet effet, une enquête a été réalisée auprès de trente (30) transformatrices spécialisées dans le fumage du poisson. Les données relatives aux espèces de poissons fumés, aux procédés et équipements de fumage puis aux contraintes des transformatrices de poisson ont été collectées sur cinq (05) sites de fumage préalablement identifiés (Calavi Kpota, Xwlacodji, Bohicon, Dangbo et Comé) à raison de six (06) transformatrices par site. Les qualités physicochimiques et micro
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48

Hum, Gabriel, Krista Wooler, Jeremy Lee, and Scott D. Taylor. "Cyclic five-membered phosphinate esters as transition state analogues for obtaining phosphohydrolase antibodies." Canadian Journal of Chemistry 78, no. 5 (2000): 642–55. http://dx.doi.org/10.1139/v00-068.

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Two novel cyclic five-membered phosphinate esters (6 and 7) were synthesized and used as transition state analogues (TSAs) for raising phosphohydrolase antibodies. The key step in the syntheses was a McCormack reaction between (2-chloroethyl)dichlorophosphite and 1,4-diphenyl-1,3-butadiene to form isomeric cyclic phosphinyl chlorides which upon further elaboration yielded the TSAs. X-ray crystal structures of two cyclic phosphinate TSA precursors (14a and 14b) show highly compressed CPC bond angles of 94°-97° indicating that the CPC bond angles in 6 and 7 are significantly distorted towards th
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Tairum, Carlos A., Melina Cardoso Santos, Carlos Alexandre Breyer, et al. "Tsa1 and Tsa2 Are Two Highly Similar 2-Cys Prx from Yeast That Display Remarkable Differences in Their Structural Switches." Free Radical Biology and Medicine 100 (November 2016): S110—S111. http://dx.doi.org/10.1016/j.freeradbiomed.2016.10.284.

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Harris, Marilyn D. "Tsao Foundation." Home Healthcare Now 39, no. 1 (2021): 52. http://dx.doi.org/10.1097/nhh.0000000000000917.

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