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1

Cheon, J., F. Hong, T. Hidaka, H. Koshikawa, and H. Tsuno. "Microbial population dynamics in a thermophilic methane digester fed with garbage." Water Science and Technology 55, no. 10 (2007): 175–82. http://dx.doi.org/10.2166/wst.2007.320.

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The diversity of microbial communities in three full-scale thermophilic anaerobic digesters which treated garbage, sewage sludge and livestock wastes (hereafter called TGD, TSD and TLD, respectively) was investigated using 16S rDNA clone libraries in triplicate. The population dynamics of TGD were also studied. The purposes were to show the microbial diversity in each reactor and to suggest which key microbes in a thermophilic methane digester fed with garbage, including a check of reproducibility and the suggestion of an error range in this molecular biology method. 736 clones were identified
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2

Yao, Yong Zhao, Yukari Ishikawa, Yoshihiro Sugawara, et al. "Dislocations in SiC Revealed by NaOH Vapor Etching and a Comparison with X-Ray Topography Taken with Various g-Vectors." Materials Science Forum 858 (May 2016): 389–92. http://dx.doi.org/10.4028/www.scientific.net/msf.858.389.

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Threading dislocations (TDs) in 4H-SiC have been studied by comparing etch pits formed by NaOH vapor etching with results of synchrotron monochromatic-beam X-ray topography (XRT) taken under different g-vectors. Burgers vectors determined based on XRT results were utilized to investigate the etch pit characteristics of edge (TED), screw (TSD) and mixed (Burgers vector b=c+a, TMD) threading dislocations. It has been found that pit formation by NaOH vapor etching was very different to that by conventional molten KOH etching. We discuss the possibility of using NaOH vapor etching to distinguish T
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3

Yao, Yong Zhao, Yukari Ishikawa, Yoshihiro Sugawara, et al. "Dislocation Revelation for 4H-SiC by Using Vaporized NaOH: A Possible Way to Distinguish Edge, Screw and Mixed Threading Dislocations by Etch Pit Method." Materials Science Forum 778-780 (February 2014): 346–49. http://dx.doi.org/10.4028/www.scientific.net/msf.778-780.346.

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In this paper, we report a newly developed dislocation-revealing etch pit method for 4H-SiC single crystal, which can distinguish edge (TED, Burgers vector b=a), elementary screw (TSD, b=1c) and mixed (TMD, b=c+a) threading dislocations. In this method, vaporized NaOH gas was used to etch the Si-face of a SiC wafer at substrate temperature around 950 °C. By a side-by-side comparison between the optical images of the etch pits and the X-ray topographic (XRT) images, it has been found that threading dislocations (TDs) in SiC could be revealed as hexagonal etch pits with distinct geometrical feat
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4

Yamamoto, Kensaku, M. Nagaya, H. Watanabe, E. Okuno, T. Yamamoto, and S. Onda. "Influence of Threading Dislocations on Lifetime of Gate Thermal Oxide." Materials Science Forum 717-720 (May 2012): 477–80. http://dx.doi.org/10.4028/www.scientific.net/msf.717-720.477.

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The reliability of gate oxides is a fundamental issue for realizing SiC MOSFETs. Many reports said that crystal defects shorten the lifetime of the gate oxide. And, epi defects, the basal plane dislocations and threading screw dislocations (TSD) are considered killer defects. However, because of the high TSD density of commercial SiC wafers, the exact relationship between other kinds of dislocations with lifetime has not been revealed. On the other hand, RAF wafers that we developed have low TSD density, so it is easy to evaluate the relationship between other kinds of dislocations and lifetim
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5

Kaur, Savreen. "Evaluation of Effectiveness of Three Different Behavioral Modification Techniques among 4–8-year-old Children." Current Trends in Dentistry 1, no. 1 (2024): 33–37. http://dx.doi.org/10.4103/ctd.ctd_7_24.

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Abstract Background: Dental anxiety being attributed by many as a major cause to avoid seeking dental care by children, so several communicative, advanced, and pharmacological interventions have been developed to manage children’s anxious and cooperative behaviors. Aim: To evaluate the effectiveness of tell–show–do (TSD), tell–play–do (TPD), and ask–tell–ask (ATA) behavioral modification techniques among 4–8 years old coming for a restorative treatment. Materials and Methods: Thirty children aged 4–8 years were enrolled in the study and randomly allocated to three groups, 10 children in each g
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6

Kurczewska, Ewa, Ewa Ferensztajn-Rochowiak, Anna Jasińska-Mikołajczyk, Maria Chłopocka-Woźniak, and Janusz K. Rybakowski. "Augmentation of Pharmacotherapy by Sleep Deprivation with Sleep Phase Advance in Treatment-Resistant Depression." Pharmacopsychiatry 52, no. 04 (2018): 186–92. http://dx.doi.org/10.1055/a-0695-9138.

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Abstract Introduction The aim was to assess the efficacy of total sleep deprivation (TSD) with sleep phase advance (SPA) in treatment-resistant depression (TRD) and associated biochemical factors. Methods We studied nine males and 12 females, aged 49±14 years, with treatment-resistant unipolar or bipolar depression, receiving antidepressant and mood-stabilizing drugs. The four-day schedule included single TSD and three consecutive nights with SPA. Biochemical markers were measured on the day before and on 1st, 7th and 14th day after the TSD. Results Ten subjects met criteria for response, defi
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7

Kurczewska, Ewa, Ewa Ferensztajn-Rochowiak, Maria Chłopocka-Woźniak, and Janusz Rybakowski. "Sleep deprivation with sleep phase advance in treatment-resistant depression therapy in relation to features of circadian rhythm and temperament – a pilot study." Pharmacotherapy in Psychiatry and Neurology 34, no. 4 (2019): 249–62. http://dx.doi.org/10.33450/fpn.2019.01.001.

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Objectives. The efficacy of pharmacotherapy augmentation by total sleep deprivation (TSD) with sleep phase advance (SPA) was evaluated in patients with treatment-resistant depression (TRD). The study examined the relationship between chronotype, affective temperaments and clinical improvement resulting from the treatment. Material and methods. The study group comprised of 30 persons with treatment-resistant unipolar (n = 15) or bipolar (n = 15) depression aged 52 ± 12 years (17 women and 13 men). TSD and three consecutive nights with SPA were used during pharmacotherapy. Severity of depression
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8

Shin, Eun-Sun, Mi-Jeong Yang, Kyung Hwa Jung, et al. "Influence of the Transposition of the Thermostabilizing Domain of Clostridium thermocellum Xylanase (XynX) on Xylan Binding and Thermostabilization." Applied and Environmental Microbiology 68, no. 7 (2002): 3496–501. http://dx.doi.org/10.1128/aem.68.7.3496-3501.2002.

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ABSTRACT A xylanase gene, xynX, of Clostridium thermocellum had one thermostabilizing domain (TSD) between the signal peptide sequence and the catalytic domain (CD). The TSD of a truncated xylanase gene, xynX′TSD-CD, was transpositioned from the N terminus to the C terminus of the CD by overlapping PCRs, and a modified product, xynX′CD-TSD, was constructed. XynX′TSD-CD had a higher optimum temperature (70°C versus 65°C) and was more thermostable (residual activity of 68% versus 46% after a 20-min preincubation at 70°C) than the one without the TSD, XynX′CD. However, the domain-transpositioned
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9

Lian, Jie, Lin Xu, Tao Song, et al. "Reduced Resting-State EEG Power Spectra and Functional Connectivity after 24 and 36 Hours of Sleep Deprivation." Brain Sciences 13, no. 6 (2023): 949. http://dx.doi.org/10.3390/brainsci13060949.

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Total sleep deprivation (TSD) leads to cognitive decline; however, the neurophysiological mechanisms underlying resting-state electroencephalogram (EEG) changes after TSD remain unclear. In this study, 42 healthy adult participants were subjected to 36 h of sleep deprivation (36 h TSD), and resting-state EEG data were recorded at baseline, after 24 h of sleep deprivation (24 h TSD), and after 36 h TSD. The analysis of resting-state EEG at baseline, after 24 h TSD, and after 36 h TSD using source localization analysis, power spectrum analysis, and functional connectivity analysis revealed a dec
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10

Derardja, Ala eddine, and Malika Barkat. "Effect of traditional sun-drying and oven-drying on carotenoids and phenolic compounds of apricot (Prunus armeniaca L.)." North African Journal of Food and Nutrition Research 3, no. 6 (2019): 186–94. http://dx.doi.org/10.51745/najfnr.3.6.186-194.

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Background: The indubitable role of phytochemicals such as carotenoids and phenolic compounds in human health has prompted the researchers to study the factors affecting the stability and the availability of these compounds. Aims: This study investigates the effect of two drying processes; oven-drying (OD) and traditional sun-drying (TSD) on carotenoids and phenolic compounds of apricots. Material and Methods: OD was performed at 65°C, and TSD was performed by direct exposure of apricot to sunlight at daytime temperatures around 40°C and relative humidity between 25 and 35%, following an Alger
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Derardja, Ala eddine, and Malika Barkat. "Effect of traditional sun-drying and oven-drying on carotenoids and phenolic compounds of apricot (Prunus armeniaca L.)." North African Journal of Food and Nutrition Research 03, no. 06 (2019): 186–94. https://doi.org/10.5281/zenodo.3497409.

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BACKGROUND: The indubitable role of phytochemicals such as carotenoids and phenolic compounds in human health has prompted the researchers to study the factors affecting the stability and the availability of these compounds. AIMS: This study investigates the effect of two drying processes; oven-drying (OD) and traditional sun-drying (TSD) on carotenoids and phenolic compounds of apricots. METHODS AND MATERIAL: OD was performed at 65°C, and TSD was performed by direct exposure of apricot to sunlight at daytime temperatures around 40°C and relative humidity between 25 and 35%, following
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12

Kim, Jeesae. "The Allure of Trade and Sustainable Development Chapters." Michigan Journal of International Law, no. 46.2 (2025): 337. https://doi.org/10.36642/mjil.46.2.allure.

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Beginning in 2011, the European Union (“EU”) began to include independent Trade and Sustainable Development (“TSD”) chapters in its trade agreements. These chapters seek to protect international labor standards, environmental laws, and corporate social responsibility practices within the scope of the EU’s trade agreements. Trading states that sign onto TSD chapters are meant to engage in ongoing dialogue regarding the substantive commitments outlined in the chapters. If one of the states fails to uphold its substantive commitments, the other state may invoke a unique enforcement mechanism cont
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13

Pasetes, Lauren, Kathleen Rosendahl-Garcia, and Namni Goel. "0173 Baseline Actigraphic Sleep Measures Predict Cardiovascular Responses to Sleep Deprivation and Psychological Stress." SLEEP 47, Supplement_1 (2024): A74—A75. http://dx.doi.org/10.1093/sleep/zsae067.0173.

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Abstract Introduction We determined whether baseline sleep measures the night before total sleep deprivation (TSD) predicted cardiovascular (CV) responses to TSD and to TSD and psychological stress. Methods We conducted a five-day experiment under controlled conditions in thirty-two healthy adults (ages 27-53; 14 females). During this experiment, CV measures were collected via echocardiography or blood pressure monitor at four assessment time points: 1) after two baseline 8h time in bed (TIB) nights (B1, B2); 2) in the morning of TSD (TSD AM; after 25h of TSD); 3) in the evening of TSD followi
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Yin, DengKe, ZhuQing Liu, DaiYin Peng, et al. "Serum Containing Tao-Hong-Si-Wu Decoction Induces Human Endothelial Cell VEGF Production via PI3K/Akt-eNOS Signaling." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/195158.

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Tao-Hong-Si-Wu decoction (TSD) is a famous traditional Chinese medicine (TCM) and widely used for ischemic disease in China. TSD medicated serum was prepared after oral administration of TSD (1.6 g/kg) twice a day for 3 days in rats. TSD medicated serum induced human umbilical vein endothelial cells (HUVECs) proliferation, VEGF secretion, and nitric oxide (NO) production. These promoted effects of TSD were partly inhibited by treatment with PI3K inhibitor (LY294002) or eNOS inhibitor (L-NAME), respectively, and completely inhibited by treatment with LY294002 and L-NAME simultaneously. Western
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15

Isshiki, Toshiyuki, and Masaki Hasegawa. "Study on Formation of Dislocation Contrast in 4H-SiC Wafer in Mirror Projection Electron Microscopy Image." Materials Science Forum 821-823 (June 2015): 307–10. http://dx.doi.org/10.4028/www.scientific.net/msf.821-823.307.

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A mirror projection electron microscopy (MPJ), non destructive, high spatial resolution and high throughput method, is useful for defect inspection in silicon carbide (SiC) wafer. Previously, it was demonstrate that three type of typical dislocations in 4H-SiC, threading screw dislocation (TSD), threading edge dislocation (TED) and basal plane dislocations (BPD) can be identified in MPJ image. Origin of the contrast of dislocations in MPJ image was revealed by observation of the same wafer at as-grown and after CMP processing. Streak of TSD spot is due to surface morphology, and the contrast o
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16

Shrestha, Shivesh, Samer W. Katicha, Gerardo W. Flintsch, and Senthilmurugan Thyagarajan. "Application of Traffic Speed Deflectometer for Network-Level Pavement Management." Transportation Research Record: Journal of the Transportation Research Board 2672, no. 40 (2018): 348–59. http://dx.doi.org/10.1177/0361198118758675.

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In this paper, the traffic speed deflectometer (TSD), a device used for network level structural evaluation, is assessed. TSD testing was performed in nine states on a total of 5,928 miles (some repeated) during three time periods: November 2013, May to July 2014, and June to September 2015. This paper presents (1) the results of repeatability and comparison of the TSD with the falling weight deflectometer (FWD), (2) the results of the comparison of TSD measurements with typical pavement management system (PMS) data, and (3) an approach that can be implemented by State Highway Agencies (SHAs)
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17

Cheng, Qian Yu, Ya Fei Liu, Ze Yu Chen, et al. "Investigating Dislocation Arrays Induced by Seed Scratches during PVT 4H-SiC Crystal Growth Using Synchrotron X-Ray Topography." Defect and Diffusion Forum 434 (August 22, 2024): 71–80. http://dx.doi.org/10.4028/p-irzu7d.

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The influence of seed preparation on crystal defect generation is studied by investigating the effect of damage from surface scratches not completely removed during polishing on the seed crystal on the nucleation and evolution of dislocation arrays. Synchrotron X-ray topography is conducted on several wafers sliced from a PVT-grown 4H-SiC boule. Topographic results in conjunction with ray tracing simulation reveal the generation of TSD/TMD and TED arrays associated with the scratches in the newly grown wafer adjacent to the seed. Configuration transformation of those arrays is observed as thes
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Pasetes, Lauren, Kathleen Rosendahl-Garcia, and Namni Goel. "0179 Cardiovascular Responses to Sleep Deprivation and Psychological Stress Predict Actigraphic Sleep During Recovery." SLEEP 47, Supplement_1 (2024): A77. http://dx.doi.org/10.1093/sleep/zsae067.0179.

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Abstract Introduction We assessed whether cardiovascular (CV) responses to total sleep deprivation (TSD) and to TSD and psychological stress predicted sleep measures during that night’s recovery. Methods Thirty-two healthy adults (ages 27-53; 14 females) participated in a five-day experiment under controlled conditions. During this experiment, CV measures were collected via blood pressure monitor or echocardiography at four assessment time points: 1) after two baseline 8h time in bed (TIB) nights; 2) in the morning of TSD (TSD AM; after 25h of TSD); 3) in the evening of TSD following a modifie
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Březina, František, Zdeněk Šindelář, Richard Pastorek, and Jan Lasovský. "Coordination compounds of nickel and cobalt with the Schiff base derived from thiosemicarbazide and diacetylmonooxime." Collection of Czechoslovak Chemical Communications 54, no. 12 (1989): 3238–44. http://dx.doi.org/10.1135/cccc19893238.

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Coordination compounds with the compositions [Ni(H2TSD)2]Cl2, [Co(H2TSD)2]Cl2, [NiH2O(TSD)], [CoH2O(TSD)] and [Co(TSD)(HTSD)].2H2O were prepared, where H2TSD = HON=C(CH3)C(CH3)=N.NH.CS.NH2. Cyclic voltammetry indicated that [NiH2O(TSD)] can be oxidized and reaction of this compound with bromine yielded the nickel compound with the composition [Ni(TSD)Br]. The properties of the ligand that make it useful for stabilizing the higher oxidation states of nickel are discussed.
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Péntek, Máté, Andreas Riedl, Kai-Uwe Bletzinger, and Felix Weber. "Investigating the Vibration Mitigation Efficiency of Tuned Sloshing Dampers Using a Two-Fluid CFD Approach." Applied Sciences 12, no. 14 (2022): 7033. http://dx.doi.org/10.3390/app12147033.

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The efficiency of a Tuned Sloshing Damper (TSD) when mitigating wind-induced structural vibrations is investigated. We assessed the performance in terms of peak structural displacements and accelerations, compared to that of the Tuned Mass Damper (TMD). One load scenario considers oncoming gusts due to natural turbulence, whereas the other assumes predominant vortex shedding at a low turbulence intensity. The known optimum tuning rules for TSDs and TMDs were adopted. We combined numerical models for fluids and structures to simulate the dynamic effects caused by wind loading. A two-fluid Compu
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Pandey, Priyambana, Sonal Gupta, Rajeev K. Singh, Akil Prawin S. S., and Vinika Rathi. "Pediatric headgear: a game changer." International Journal of Contemporary Pediatrics 12, no. 5 (2025): 767–72. https://doi.org/10.18203/2349-3291.ijcp20251096.

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Background: The American academy of pediatric dentistry has recently suggested conducting additional research on nonpharmacologic therapies, despite the fact that dental clinics employ a variety of strategies to manage anxious children, including communicative, pharmacologic, and nonpharmacologic interventions. Aim of the effectiveness of two nonpharmacologic behavior management techniques, pediatric headgear (PH) and tell-show-do (TSD) technique, on dental anxiety in children. Methods: Thirty children aged between 2-5 years who were on their first dental visit were split into 2 groups. group
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22

Yamazaki, E. M., K. M. Rosendahl-Garcia, L. E. MacMullen, A. J. Ecker, J. N. Kirkpatrick, and N. Goel. "0041 Heart Rate Variability Differs in Resilient vs. Vulnerable Adults from Total Sleep Deprivation and Psychological Stress and Predicts Cognitive Performance." Sleep 43, Supplement_1 (2020): A16—A17. http://dx.doi.org/10.1093/sleep/zsaa056.040.

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Abstract Introduction There are substantial individual differences (resilience and vulnerability) in neurobehavioral performance from psychosocial stress and sleep loss. However, the time course of heart rate variability (HRV) across baseline, total sleep deprivation (TSD), the combination of TSD + psychological stress, and recovery has not been investigated; in addition, it remains unknown whether HRV and blood pressure (BP) differ in resilient vs. vulnerable individuals and predict individual differences in cognitive performance. Methods Thirty-one healthy adults (ages 27–53; mean±SD, 35.4±7
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Goel, N., E. M. Yamazaki, L. E. MacMullen, and A. J. Ecker. "0265 Cortisol and C-Reactive Protein Fail to Predict Individual Differences in Neurobehavioral Performance Responses to Total Sleep Deprivation and Psychological Stress." Sleep 43, Supplement_1 (2020): A101. http://dx.doi.org/10.1093/sleep/zsaa056.263.

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Abstract Introduction Individuals show marked differential vulnerability in neurobehavioral deficits from psychosocial stress and sleep deprivation. Although changes in salivary cortisol and C-reactive protein (CRP) typically occur across total sleep deprivation (TSD) and recovery sleep, whether these biological markers during fully rested conditions predict individual differences in cognitive performance during TSD and stress remains unknown. Methods Thirty-one healthy adults (ages 27–53; mean ± SD, 35.4 ± 7.1y; 14 females) participated in a five-day experiment consisting of two 8h time-in-be
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Goel, Namni, and Lauren Pasetes. "0172 Predictive Relationships Between Baseline and Recovery Sleep and Neurobehavioral Measures During Sleep Deprivation." SLEEP 47, Supplement_1 (2024): A74. http://dx.doi.org/10.1093/sleep/zsae067.0172.

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Abstract Introduction We investigated whether baseline sleep measures derived from actigraphy the night before total sleep deprivation (TSD) predicted cognitive performance and subjective sleepiness and fatigue during TSD. We also investigated whether these measures during TSD predicted that night’s recovery sleep. Methods Thirty-two adults (ages 27-53;14 females) participated in a five-day experiment under controlled conditions comprised of two baseline 8h time in bed (TIB) nights (B1, B2), approximately 39h of TSD, and two recovery nights of 8-10h TIB (R1=10h, R2=8h). Neurobehavioral measure
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Martin, Dianna C., Brian L. Mark, Barbara L. Triggs-Raine, and Marvin R. Natowicz. "Evaluation of the Risk for Tay-Sachs Disease in Individuals of French Canadian Ancestry Living in New England." Clinical Chemistry 53, no. 3 (2007): 392–98. http://dx.doi.org/10.1373/clinchem.2006.082727.

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Abstract Background: The assessment of risk for Tay-Sachs disease (TSD) in individuals of French Canadian background living in New England is an important health issue. In preliminary studies of the enzyme-defined carrier frequency for TSD among Franco-Americans in New England, we found frequencies (1:53) higher than predicted from the incidence of infantile TSD in this region. We have now further evaluated the risk for TSD in the Franco-American population of New England. Methods: Using a fluorescence-based assay for β-hexosaminidase activity, we determined the carrier frequencies for TSD in
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Moritani, Tatsuru, Hayato Usui, Tadahiko Morinaga, Hideyuki Sato, and Satomi Onoue. "Cyclosporine A-Loaded Ternary Solid Dispersion Prepared with Fine Droplet Drying Process for Improvement of Storage Stability and Oral Bioavailability." Pharmaceutics 15, no. 2 (2023): 571. http://dx.doi.org/10.3390/pharmaceutics15020571.

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This study aimed to develop a cyclosporine A (CsA)-loaded ternary solid dispersion (tSD/CsA) to improve the storage stability of a solid dispersion (SD) system and the oral absorbability of CsA. Hydroxypropyl cellulose (HPC) and hydroxypropyl methylcellulose acetate succinate (HPMCAS) were selected as carrier materials of tSD, and tSD/CsA was prepared with a fine droplet drying process, a powderization technology that employs an inkjet head. The physicochemical properties of tSD/CsA were evaluated in terms of morphology, storage stability, dissolution behavior, and mucoadhesive property. After
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27

Nielsen, Christoffer P. "Visco-Elastic Back-Calculation of Traffic Speed Deflectometer Measurements." Transportation Research Record: Journal of the Transportation Research Board 2673, no. 12 (2019): 439–48. http://dx.doi.org/10.1177/0361198118823500.

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The traffic speed deflectometer (TSD) has proven a valuable tool for network level structural evaluation. At the project level, however, the use of TSD data is still quite limited. An obstacle to the use of TSD at the project level is that the standard approaches to back-calculation of pavement properties are based on the falling weight deflectometer (FWD). The FWD experiment is similar, but not equivalent, to the TSD experiment, and therefore it is not straightforward to apply the traditional FWD back-calculation procedures to TSD data. In this paper, a TSD-specific back-calculation procedure
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Lian, Jie, Lin Xu, Tao Song, et al. "Decreased Functional Connectivity of Brain Networks in the Alpha Band after Sleep Deprivation Is Associated with Decreased Inhibitory Control in Young Male Adults." International Journal of Environmental Research and Public Health 20, no. 5 (2023): 4663. http://dx.doi.org/10.3390/ijerph20054663.

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Sleep deprivation leads to reduced inhibitory control in individuals. However, the underlying neural mechanisms are poorly understood. Accordingly, this study aimed to investigate the effects of total sleep deprivation (TSD) on inhibitory control and their neuroelectrophysiological mechanisms from the perspective of the time course of cognitive processing and brain network connectivity, using event-related potential (ERP) and resting-state functional connectivity techniques. Twenty-five healthy male participants underwent 36 h of TSD (36-h TSD), completing Go/NoGo tasks and resting-state data
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Prence, Elizabeth M., Cheryl A. Jerome, Barbara L. Triggs-Raine, and Marvin R. Natwicz. "Heterozygosity for Tay-Sachs and Sandhoff Diseases among Massachusetts Residents with French Canadian Background." Journal of Medical Screening 4, no. 3 (1997): 133–36. http://dx.doi.org/10.1177/096914139700400304.

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Objectives— The frequency of Tay-Sachs disease (TSD) heterozygosity is increased among French Canadians in eastern Quebec. A large proportion of the New England population has French Canadian heritage; thus, it is important to determine if they too are at increased risk for TSD heterozygosity. This prospective study was designed to assess the TSD heterozygote frequency among people with French Canadian background living in Massachusetts. A simultaneous screen for heterozygosity for Sandhoff disease, a related genetic disorder, was also undertaken. Methods— 1260 non-pregnant subjects of French
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Yamazaki, E. M., K. M. Rosendahl-Garcia, L. E. MacMullen, A. J. Ecker, J. N. Kirkpatrick, and N. Goel. "0042 Stroke Volume and Cardiac Index are Differentially Altered by Total Sleep Deprivation and Psychological Stress in Resilient vs. Vulnerable Individuals and Predict Cognitive Performance." Sleep 43, Supplement_1 (2020): A17. http://dx.doi.org/10.1093/sleep/zsaa056.041.

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Abstract Introduction Individuals show robust resilience and vulnerability in neurobehavioral performance to sleep loss and stress. For the first time, we investigated the time course of two cardiovascular measurements, stroke volume (SV) and cardiac index (CI), both derived from echocardiography, across baseline, total sleep deprivation (TSD), the combination of TSD+psychological stress, and recovery. We also determined whether these variables differ in resilient vs. vulnerable individuals and whether they predict differential vulnerability in cognitive performance. Methods Thirty-one healthy
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Skeiky, Lillian, Kirsie Lundholm, Sean Hovland, et al. "0064 Sleep Loss Affects Item and Source Memory Differentially as a Function of Serotonin Transporter (5-HTTLPR) Genotype." SLEEP 47, Supplement_1 (2024): A29. http://dx.doi.org/10.1093/sleep/zsae067.0064.

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Abstract Introduction Remembering relationships between items (information) and the contexts (sources) in which they are framed is crucial for everyday functioning. Total sleep deprivation (TSD) impairs this ability, with evidence suggesting that TSD affects source memory even when items are remembered. Source memory deficits imply problems with associative memory, which relies on hippocampal functioning, known to be altered by TSD. Serotonin is highly expressed in the hippocampus, is influenced by TSD, and may be part of a mechanism by which TSD degrades source memory. We investigated the ass
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Gordijn, M. C. M., D. G. M. Beersma, A. L. Bouhuys, H. J. Korte, and R. H. van den Hoofdakker. "A longitudinal study of sleep deprivation responses in depression; The variability is highly related to diurnal mood variability." Acta Neuropsychiatrica 7, no. 2 (1995): 58–60. http://dx.doi.org/10.1017/s0924270800037583.

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Unequivocal results demonstrating a causal relationship between a disturbance in circadian rhythms and depression have not yet been reported (reviews). However, acute mood changes, such as the antidepressive effect of sleep deprivation, diurnal variations of mood and their interrelationship, are commonly put forward as evidence of the importance of circadian dysregulations in affective disorders. The purpose of the present study is to obtain more insight in the mechanisms underlying these mood changes. The results will be discussed in the context of a recently postulated non-chronobiological e
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Xie, Zihuang, Yimin Zhu, Yijia Hu, Yao Ha, and Zhong Zhong. "A Statistical Prediction Model for Summer Precipitation in China Based on TSD Method and EOF Modes’ Time Coefficients." Sustainability 15, no. 14 (2023): 10928. http://dx.doi.org/10.3390/su151410928.

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It is a challenge to improve the skill of seasonal precipitation prediction, because there are many factors affecting summer precipitation in China, which are found on different time scales and have complex interactions with each other. For these reasons, we establish a prediction model with the time-scale decomposition (TSD) method to investigate whether the TSD has an improving effect on the prediction skill of summer precipitation in China. Using this statistical model, the predictors and predictands will be separated into interannual and interdecadal time scales, after which Empirical Orth
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Finlay, Myles, Devon Hansen, Lillian Skeiky, and Hans Van Dongen. "332 Non-REM EEG Spectral Power at Baseline and After Total Sleep Deprivation in Individuals with Sleep-Onset Insomnia." Sleep 44, Supplement_2 (2021): A133. http://dx.doi.org/10.1093/sleep/zsab072.331.

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Abstract Introduction The baseline non-REM sleep EEG of individuals with insomnia has been found to display increased spectral power at frequencies >14Hz, which may reflect hyperarousal. There is some evidence in this population of reduced slow wave activity after total sleep deprivation (TSD), potentially indicating altered sleep homeostasis. We investigated non-REM sleep EEG spectra at baseline and after TSD in individuals with sleep-onset insomnia. Methods 10 individuals with sleep-onset insomnia and 5 healthy controls (ages 22-40y, 11 females) completed a 5-day laboratory study with
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Yi, Zi-Yun, Qiu-Xia Liang, Qian Zhou, et al. "Maternal total sleep deprivation causes oxidative stress and mitochondrial dysfunction in oocytes associated with fertility decline in mice." PLOS ONE 19, no. 10 (2024): e0306152. http://dx.doi.org/10.1371/journal.pone.0306152.

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Previous studies have shown sleep deprivation is increasingly reported as one of the causes of female infertility. However, how and by what relevant mechanisms it affects female fertility remains unclear. In this study, female mice underwent 72 hours of total sleep deprivation (TSD) caused by rotating wheel or 2 different controls: a stationary wheel, or forced movement at night. Even though, there was no significant difference in the number of eggs ovulated by the TSD mice compared to the control groups. Overall levels of estrogen and FSH were lower throughout the estrus cycle. A total of 42
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Ellison, Alexandre, Erik Sörman, Björn Sundqvist, et al. "Mapping of Threading Screw Dislocations in 4H n-Type SiC Wafers." Materials Science Forum 858 (May 2016): 376–79. http://dx.doi.org/10.4028/www.scientific.net/msf.858.376.

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X-ray topography shows that selective KOH etching after CVD growth of n-type epilayers on highly N doped 4H SiC substrates can be used to reliably map pure and mixed Threading Screw Dislocations (TSD). The influence of the mapping grid density and the wafer position in the crystal on the average TSD density are investigated. A reliable mapping of TSD contributed to the development of 100mm SiC wafers with average TSD density down to 200 cm-2.
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Kant, Shashi. "The marginal cost of structural diversity of mixed uneven-aged hard maple forests." Canadian Journal of Forest Research 32, no. 4 (2002): 616–28. http://dx.doi.org/10.1139/x02-001.

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Theoretical concepts pertaining to the marginal cost (MC) of the structural diversity of a forest stand are developed. A matrix growth model is estimated for mixed uneven-aged forest stands of hard maple (Acer saccharum Marsh.) from southern Ontario. The estimated growth model is used to derive the MC equations for the Shannon and the Simpson indices of total structural diversity (TSD), species diversity (SD), and tree-size diversity (TD). The effects of exclusion and inclusion of the opportunity cost (OC) on the MC of the TSD are compared. The contributions of SD and TD to the MC of the TSD a
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Yin, Ying, Shufang Chen, Tao Song, Qianxiang Zhou, and Yongcong Shao. "Cognitive Load Moderates the Effects of Total Sleep Deprivation on Working Memory: Evidence from Event-Related Potentials." Brain Sciences 13, no. 6 (2023): 898. http://dx.doi.org/10.3390/brainsci13060898.

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Purpose: The function of working memory (WM) is impaired by total sleep deprivation (TSD) and cognitive load. However, it is unclear whether the load modulates the effect of TSD on WM. We conducted a pilot study to investigate the effects of 36 h of TSD on WM under different load levels. Materials and methods: Twenty-two male students aged 18–25 years were enrolled, who underwent two types of sleep conditions (baseline and 36 h TSD), where they performed two N-back WM tasks (one-back task and two-back task) with simultaneous electroencephalography recordings. Results: Repeated measures analysi
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Johnsen, Clark, and Helen T. Ding. "Therapist self-disclosure: Let’s tackle the elephant in the room." Clinical Child Psychology and Psychiatry 26, no. 2 (2021): 443–50. http://dx.doi.org/10.1177/1359104521994178.

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Therapist Self-Disclosure (TSD), the revealing of a therapist’s feelings, thoughts or personal information to a client, is an inevitable aspect of therapeutic relationships. However, despite its prevalence in clinical settings, we believe there is insufficient recognition and exploration of TSD in our work with children and adolescents. Because TSD is not often formally addressed during training, therapists across the spectrum of clinical child psychology and psychiatry are often left with the belief that disclosures are rare or inherently negative occurrences that should be avoided. As a bypr
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Miró, Elena, Carmen Cano, and Gualberto Buela-Casal. "Effects of Total Sleep Deprivation on Cardiovascular Parameters: An Absence of Biologically Significant Findings?" Journal of Psychophysiology 16, no. 2 (2002): 119–26. http://dx.doi.org/10.1027//0269-8803.16.2.119.

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Abstract The present study analyzes the variations of heart rate (HR) and systolic and diastolic blood pressure (SBP and DBP) during 60 h of total sleep deprivation (TSD). All variables were evaluated every 2 h in a resting condition, during the performance of a vigilance task. Thirty healthy volunteers (15 men and 15 women) from 18 to 24 years old participated in the experiment. The analyses of variance (ANOVAS) with repeated measures showed some modifications of HR and SBP mean values mainly marked by circadian oscillations. The circadian oscillations had a smaller amplitude for SBP than for
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Han, Lan, Zhaojie Ji, Weidong Chen, et al. "Protective Effects of Tao-Hong-Si-Wu Decoction on Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/195835.

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Tao-Hong-Si-Wu decoction (TSD) as a traditional chinese medicine (TCM) has been developed to treat thrombotic diseases for hundreds of years, and vascular dementia (VD) is a cognitive dysfunction syndrome caused by cerebral embolism. In this study, the protective effect of TSD on memory impairment and brain damage in rat model of VD induced by middle cerebral artery occlusion (MCAO) was investigated. The study showed that rats in MCAO treatment with TSD for 14 days significantly improved behavioral function, increased densities of neuron, and induced angiogenesis in the brain compared with mod
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Rasemi Widayanti, Marcellina, and Irine Yunila Prastyawati. "Korelasi Usia Dengan Tekanan Darah Sistolik-Diastolik, Indeks Massa Tubuh, Kadar Kolestrol Pada Lansia." JURNAL KESEHATAN MERCUSUAR 6, no. 1 (2023): 20–25. http://dx.doi.org/10.36984/jkm.v6i1.352.

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Penyakit degeneratif masih menjadi tantangan karena perkembangan lansia terus meningkat setiap tahunnya. Tujuan penelitian ini adalah mengetahui hubungan usia dengan tekanan darah sistolik-diastolik, indeks massa tubuh, kadar kolesterol di RT 3 RW 12 Kedung Anyar Surabaya. Desain penelitian adalah observasional analitik dengan pendekatan cross sectional, jumlah sampel 44 responden lansia Kedung Anyar Surabaya dan diuji menggunakan Pearson. Hasil menunjukkan jenis kelamin 68% perempuan. Usia rata-rata responden 53,66 tahun. Rata-rata Tekanan Darah Sistolik (TDS) responden adalah 133 mmHg. Nilai
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Tang, Zhi, Ming Yin, Yuxing Guo та ін. "Taohong Siwu Decoction Promotes Osteo-Angiogenesis in Fractures by Regulating the HIF-1α Signaling Pathway". Evidence-Based Complementary and Alternative Medicine 2022 (20 вересня 2022): 1–10. http://dx.doi.org/10.1155/2022/6777447.

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Background. Vascular damage is a major consequence of bone fracture. Taohong Siwu decoction (TSD) can raise the expression of vascular endothelial growth factor (VEGF) in fracture healing. However, its molecular mechanism in promoting angiogenesis is still unknown. The aim of this study was to investigate the potential mechanisms of TSD in the regulation of osteo-angiogenesis in fracture healing. Methods. A rat tibial fracture model was established. After low- (4.5 g·kg−1), medium- (9 g·kg−1), and high-dose TSD (18 g·kg−1) and panax notoginsenoside (25 mg kg−1) treatment, hematoxylin-eosin sta
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Carter, Jason R., John J. Durocher, Robert A. Larson, Joseph P. DellaValla, and Huan Yang. "Sympathetic neural responses to 24-hour sleep deprivation in humans: sex differences." American Journal of Physiology-Heart and Circulatory Physiology 302, no. 10 (2012): H1991—H1997. http://dx.doi.org/10.1152/ajpheart.01132.2011.

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Sleep deprivation has been linked to hypertension, and recent evidence suggests that associations between short sleep duration and hypertension are stronger in women. In the present study we hypothesized that 24 h of total sleep deprivation (TSD) would elicit an augmented pressor and sympathetic neural response in women compared with men. Resting heart rate (HR), blood pressure (BP), and muscle sympathetic nerve activity (MSNA) were measured in 30 healthy subjects (age, 22 ± 1; 15 men and 15 women). Relations between spontaneous fluctuations of diastolic arterial pressure and MSNA were used to
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Goel, Namni, Kathleen Rosendahl-Garcia, and Lauren Pasetes. "0207 Acute Total Sleep Deprivation Adversely Impacts Cardiovascular Measures across Long-Duration Intervals." SLEEP 46, Supplement_1 (2023): A92. http://dx.doi.org/10.1093/sleep/zsad077.0207.

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Abstract Introduction For the first time, we comprehensively investigated the effects of repeated exposures to baseline (BL), total sleep deprivation (TSD), and recovery (REC) phases at 2, 4, and 8 months on cardiovascular (CV) measures. Methods We conducted a five-day experiment twice (at months 2 and 4) in a 4-month study (N=6 healthy adults; 3 females), and a similar five-day experiment three times (at months 2, 4, and 8) in an 8-month study (N=5 healthy adults; 2 females). During these repeated experiments, CV measures were collected via echocardiography or blood pressure monitor [systolic
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Logioia, Gisella, Courtney Kurinec, and Devon Hansen. "0253 Total Sleep Deprivation Impairs Decision Making More in Healthy Sleepers Than in Individuals with Chronic Insomnia." SLEEP 48, Supplement_1 (2025): A111. https://doi.org/10.1093/sleep/zsaf090.0253.

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Abstract Introduction Work in healthcare routinely involves night and rotating shifts, early morning starts, and variable call schedules, resulting in short and/or disrupted sleep. We conducted a laboratory-based experiment in both normal sleepers and those with chronic insomnia to better understand implications of total sleep deprivation (TSD) on decision making using a reversal learning task (i.e., go/no go; GNG) with unannounced reversal contingences. Methods 28 individuals completed the sleep study, 15 with sleep-onset insomnia (ages 22-40, 11 females), of whom 7 underwent TSD, and 13 norm
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Isaksson, A., B. Hultberg, P. Masson, E. Landels, and A. Fensom. "Enzyme immunoassay of beta-hexosaminidase A and B in serum: carrier detection of GM2-gangliosidoses, and equivalence of enzyme activity and enzyme protein reactivity." Clinical Chemistry 39, no. 7 (1993): 1412–15. http://dx.doi.org/10.1093/clinchem/39.7.1412.

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Abstract beta-Hexosaminidase (Hex; EC 3.2.1.52) isoenzymes A and B were analyzed in sera from a control group of 22 apparently healthy subjects, 13 obligate carriers of Tay-Sachs disease (TSD), 10 obligate carriers of Sandhoff disease (SHD), and 4 affected TSD patients by enzyme immunoassay methods based on enzyme activity. No Hex A activity was detected in the sera of patients with TSD. The activities of Hex A in the obligate carriers of TSD and SHD tended to be lower (nonsignificantly) than in the control group. Hex B activities tended to be higher in TSD patients as well as in carriers of T
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Arjadi, Fitranto, Wahyudin Wahyudin, and Joko Setyono. "Differences in body weight post-induction sleep deprivation and sleep recovery in white male rats (Rattus norvegicus)." AcTion: Aceh Nutrition Journal 8, no. 2 (2023): 219. http://dx.doi.org/10.30867/action.v8i2.930.

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Sleep Deprivation (SD) reduced leptin levels, increased ghrelin levels, and it caused were multifactorial, so research was conducted on experimental animals to prove whether SD was the single factor causing changes in body weight (BW). The study's objectives were to know the difference in BW after induction of paradoxical and total SD and to observe the improvement in sleep recovery (SR). This study was true experimental with posttest only, and a control group design used 25 male albino rats randomly shared into five groups; control, PSD, TSD, PSD+SR, dan TSD+SR on August – September 2021. The
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Xu, Xuefeng, Jiakui Tang, Na Zhang, Anan Zhang, Wuhua Wang, and Qiang Sun. "Mapping Temperate Grassland Dynamics in China Inner Mongolia (1980s–2010s) Using Multi-Source Data and Deep Neural Network." Remote Sensing 17, no. 10 (2025): 1779. https://doi.org/10.3390/rs17101779.

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As a vital part of the Eurasian temperate grassland, the Chinese temperate grassland is primarily distributed in the Inner Mongolia Plateau. This paper focuses on mapping temperate grassland dynamics from the 1980s to the 2010s in Inner Mongolia, which was divided into temperate meadow steppe (TMS), temperate typical steppe (TTS), temperate desert steppe (TDS), temperate steppe desert (TSD) and temperate desert (TD). Multi-source features, including multispectral reflectance, vegetation growth, topography, water bodies, meteorological data, and soil characteristics, were selected based on thei
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Xiong, Liang-Bin, Jia-Lin Li, Bo Yang, and Ying Yu. "Ti3+in the Surface of Titanium Dioxide: Generation, Properties and Photocatalytic Application." Journal of Nanomaterials 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/831524.

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Titanium dioxide (TiO2) is the most investigated crystalline oxide in the surface science of metal oxides. Its physical and chemical properties are dominantly determined by its surface condition. Ti3+surface defect (TSD) is one of the most important surface defects in TiO2. According to publications by other groups and the studies carried out in our laboratory, the formation mechanism of TSD is proposed. The generation, properties, and photocatalytic application of TSD are overviewed; the recent exploration of TSD is summarized, analyzed, and evaluated as well in this paper.
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