Relevant bibliographies by topics / TSH Secreting Pituitary Adenomas

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  2. Dissertations / Theses
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Academic literature on the topic 'TSH Secreting Pituitary Adenomas'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "TSH Secreting Pituitary Adenomas"

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Skinner, Monica M., Ralf Nass, Beatriz Lopes, Edward R. Laws, and Michael O. Thorner. "Growth Hormone Secretagogue Receptor Expression in Human Pituitary Tumors1." Journal of Clinical Endocrinology & Metabolism 83, no. 12 (1998): 4314–20. http://dx.doi.org/10.1210/jcem.83.12.5307.

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The GH secretagogue (GHS) receptor (GHS-R) has been characterized and cloned. It is a member of a family of seven transmembrane receptors and is closely related to the neurotensin and TRH receptors. To determine the expression of this receptor in normal anterior pituitary and in 24 human pituitary adenomas, we analyzed GHS-R messenger ribonucleic acid (mRNA) using a RT-PCR assay. We found that normal human pituitary was positive for the GHS-R signal. In addition, all GH-secreting adenomas and the one TSH-secreting adenoma demonstrated the presence of GHS-R mRNA. Three of four ACTH-secreting tu
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Tkachuk, Arina V., Tatiana A. Grebennikova, Anastasiya M. Lapshina, Victoria P. Vladimirova, Zhanna E. Belaya, and Galina A. Melnichenko. "TSH-secreting pituitary adenoma in combination with primary hypothyroidism in the outcome of Hashimoto’s disease: diagnostic difficulties." Clinical and experimental thyroidology 14, no. 3 (2018): 162–68. http://dx.doi.org/10.14341/ket10021.

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Despite the fact that pituitary adenomas are among the most frequent brain tumours, TSH-secreting pituitary adenomas (thyrotropinomas) are less than 1% of all adenomas. Due to the increase in the free fractions of thyroid hormones at normal or elevated TSH levels, the majority of patients with these pituitary adenomas have a long anamnesis of thyrotoxicosis which requires a differential diagnosis with thyroid pathology (Graves’ disease, toxic adenoma, autonomously functioning thyroid nodules). The diagnosis of the thyrotropinoma is quite challenging for clinicians. This article describes the c
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Dzeranova, L. K., A. S. Shutova, E. A. Pigarova, et al. "Long action somatostatin analogues in patients with TSH-secreted pituitary adenomas: treatment experience." Obesity and metabolism 18, no. 4 (2022): 438–46. http://dx.doi.org/10.14341/omet12768.

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Thyrotoxicosis, which characteristics are increased excitability, emotional lability, tachycardia episodes, increasing of free fractions of tetraiodothyronine (T4) and triiodothyronine (T3) is one of the most common endocrinological syndromes. However, during the interpretation of thyroid status it is very important to take into account the possibility that a patient has TSH-secreting pituitary adenoma. Timely diagnosis of TSH-secreting adenomas plays prominent role in guiding the treatment course since it is associated with an improvement of long-term prognosis and an increase of the patient’
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Richard, Seidu A,, Songping Zheng, Chuanfen Lei, Fu Wei, Xiao Yang, and Cai Bowen. "Refractory Transposing Hyperthyroid Disorder Inducing Tsh-secreting Pituitary Adenoma: A Case Report and Literature Review." Advances in Bioscience and Clinical Medicine 7, no. 2 (2019): 64. http://dx.doi.org/10.7575/aiac.abcmed.v.7n.2p.64.

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Introduction: TSH-secreting pituitary adenomas (TSH-sPAs) or thyrotropinomas are very rare forms of pituitary adenomas (PAs). Although several authors have presented single cases or case series on this occurrence, only few authors have indicated that hyperthyroidism heralded the pathogenesis of TSH-sPA. We also present a case of refractory transposing hyperthyroid disorder inducing TSH-sPA. Case Presentation: We present a 47-year-old woman with 20 years’ history hyperthyroidism and a visible anterior neck swelling with normal TSH. She was put on anti-thyroid medications that transposed her hyp
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Souza, Paulyanara Monique Alves de, Jefferson Ricardo Rodrigues Morais, Karla Vanessa Rodrigues Morais, Josué Da Silva Brito, and Talitha Araújo Faria. "Adenoma hipofisário secretor de TSH: uma revisão sistemática / TSH-secreting pituitary adenoma: a systematic review." Arquivos Médicos dos Hospitais e da Faculdade de Ciências Médicas da Santa Casa de São Paulo 65, no. 1 (2020): 1. http://dx.doi.org/10.26432/1809-3019.2020.65.035.

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Introdução: Os adenomas hipofisários são tumores caracterizados pela proliferação de células adeno-hipofisárias produtoras de hormônios tróficos. Dentre eles, os adenomas hipofisários produtores de TSH (TSHomas), neoplasias benignas pouco frequentes, que correspondem a menos do que 3% dos adenomas hipofisários. Método: Pesquisamos os termos TSHomas, tireotropinomas e adenomas pituitários secretores de TSH nas bases Pubmed, Lilacs e Scielo. Incluímos artigos publicados entre 2010 e 2020, sendo excluídos relatos de casos, artigos indisponíveis e que não tratavam sobre o tema. Resultados e discus
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Clarke, Michelle J., Dana Erickson, M. Regina Castro, and John L. D. Atkinson. "Thyroid-stimulating hormone pituitary adenomas." Journal of Neurosurgery 109, no. 1 (2008): 17–22. http://dx.doi.org/10.3171/jns/2008/109/7/0017.

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Object Thyroid-stimulating hormone (TSH)–secreting pituitary adenomas are rare, representing < 2% of all pituitary adenomas. Methods The authors conducted a retrospective analysis of patients with TSH-secreting or clinically silent TSH-immunostaining pituitary tumors among all pituitary adenomas followed at their institution between 1987 and 2003. Patient records, including clinical, imaging, and pathological and surgical characteristics were reviewed. Twenty-one patients (6 women and 15 men; mean age 46 years, range 26–73 years) were identified. Of these, 10 patients had a history of clini
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Kostyleva, D. N., P. M. Khandaeva, A. M. Lapshina, et al. "Clinical case of plurihormonal pituitary adenoma (STH/ACTH/TSH/FSH/LH-secreting), diagnostic pitfalls." Problems of Endocrinology 70, no. 4 (2024): 24–31. http://dx.doi.org/10.14341/probl13349.

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According to numerous studies, the most common pituitary tumors are prolactinomas, reaching 60% of all clinically significant adenomas, the next in order are non-functional pituitary adenomas, somatotropinomas, corticotropinomas and thyrotropinomas. Plurigormonal tumors occur in less than 1% of all pituitary adenomas. The most common form of mixed secretion adenoma in this patient population, derived from the Pit-1 cell line, produces various combinations of hormones: growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH). This article presents a patient with a plurihormonal t
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Delhase, M., P. Vergani, A. Malur, et al. "Pit-1/GHF-1 expression in pituitary adenomas: further analogy between human adenomas and rat SMtTW tumours." Journal of Molecular Endocrinology 11, no. 2 (1993): 129–39. http://dx.doi.org/10.1677/jme.0.0110129.

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ABSTRACT Adenomas can develop from each cell type of the anterior pituitary. In the normal pituitary, three of these cell types, the GH-, prolactin- and TSH-secreting cells, express the transcription factor Pit-1/GHF-1 which is responsible for prolactin and GH (and probably TSH) cell commitment, differentiation, probably proliferation and gene expression. We have analysed the expression of Pit-1/GHF-1 in a panel of human pituitary adenomas. All GH-, prolactin- and TSH-expressing adenomas studied expressed the Pit-1/GHF-1 factor, as demonstrated by in-situ hybridization and immunocytochemistry.
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Telegina, M. A., and Zh E. Belaya. "Rare forms of thyrotoxicosis: thyrotropin-secreting pituitary adenomas." Clinical Medicine (Russian Journal) 102, no. 4 (2024): 291–96. http://dx.doi.org/10.30629/0023-2149-2024-102-4-291-296.

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Thyrotoxicosis most often occurs due to autoimmune diseases of the thyroid gland or a multi-nodular toxic goiter, but it can also be caused by TSH-secreting pituitary adenomas. In the presence of these adenomas, the levels of circulating free T3 and T4 increase in the absence of suppression, even with elevated TSH levels. Incorrect interpretation of results from studies that only measure TSH can lead to erroneous diagnoses and management strategies for patients, including unnecessary surgery or radioactive iodine therapy. This can contribute to the growth of pituitary tumors. Various tests hav
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Illouz, Frédéric, Philippe Chanson, Emmanuel Sonnet, et al. "Somatostatin receptor ligands induce TSH deficiency in thyrotropin-secreting pituitary adenoma." European Journal of Endocrinology 184, no. 1 (2021): 1–8. http://dx.doi.org/10.1530/eje-20-0484.

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Objective Somatostatin receptor ligands (SRL) are useful to control central hyperthyroidism in patients with thyrotropin-secreting pituitary adenoma (TSH pituitary adenoma). The aim of this study was to describe the frequency of thyrotropin deficiency (TSH deficiency) in patients with TSH pituitary adenoma treated by SRL. Design Retrospective study. Methods Patients with central hyperthyroidism due to TSH pituitary adenoma treated by short or long-acting SRL were retrospectively included. TSH deficiency was defined by a low FT4 associated with non-elevated TSH concentrations during SRL therapy
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Dissertations / Theses on the topic "TSH Secreting Pituitary Adenomas"

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List, Jörg V., Stephan B. Sobottka, Angela Hübner, et al. "Cushing’s Disease in a 7-Month-Old Girl due to a Tumor Producing Adrenocorticotropic Hormone and Thyreotropin-Secreting Hormone." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-135392.

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We present the case of a 7-month-old baby with Cushing’s disease due to an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma combined with cells producing thyreotropin-secreting hormone (TSH). In MRI scans, a contrast-enhancing lesion was seen inside the pituitary fossa, and it extended into the suprasellar region. On the assumption of a pituitary adenoma, surgery was performed. Corresponding with biochemical findings, histopathological evaluation revealed an ACTH- and TSH-producing tumor. Genetic analysis did not demonstrate an alteration at codon 201 (Arg) and 227 (Glu). To our
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List, Jörg V., Stephan B. Sobottka, Angela Hübner, et al. "Cushing’s Disease in a 7-Month-Old Girl due to a Tumor Producing Adrenocorticotropic Hormone and Thyreotropin-Secreting Hormone." Karger, 1999. https://tud.qucosa.de/id/qucosa%3A27645.

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We present the case of a 7-month-old baby with Cushing’s disease due to an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma combined with cells producing thyreotropin-secreting hormone (TSH). In MRI scans, a contrast-enhancing lesion was seen inside the pituitary fossa, and it extended into the suprasellar region. On the assumption of a pituitary adenoma, surgery was performed. Corresponding with biochemical findings, histopathological evaluation revealed an ACTH- and TSH-producing tumor. Genetic analysis did not demonstrate an alteration at codon 201 (Arg) and 227 (Glu). To our
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Ciato, Denis. "Novel molecular mechanisms involved in the pathogenesis of GH-secreting pituitary adenomas." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3427255.

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Pituitary tumors usually show a particular benign nature, with a slow growth potential. Despite these characteristics, they can cause severe complications due to their excessive hormone secretion. Still, further investigations are needed to understand the molecular mechanisms implicated in their development in detail. AHRR (Aryl Hydrocarbon Receptor (AHR) Repressor) and HSP90 (Heat Shock Protein 90) are good candidates for playing a role in pituitary tumorigenesis due to their tumorigenic role reported in different types of tumors and their action in the metabolism of endocrine disruptors (EDs
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Foltran, Renata Kikuchi. "Estudo molecular dos genes GNAS, PTTG, AIP, CDKN1B e MEG3 em adenomas hipofisários esporádicos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-02052016-142707/.

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INTRODUÇÃO: Os adenomas hipofisários são neoplasias benignas que representam cerca de 15% das neoplasias intracranianas. Em sua maioria ocorre de forma esporádica. Estudos moleculares desses adenomas identificaram anormalidades genéticas que podem ter um papel na sua tumorigênese. Dentre alguns desses genes foram descritos os oncogenes GNAS e PTTG e os genes supressores tumorais AIP, CDKN1B e MEG3. OBJETIVO: realizar estudo molecular dos genes associados a tumorigênese através da pesquisa de mutações nos genes GNAS, AIP e CDKN1B e o estudo de expressão gênica de CDKN1B, PTTG e MEG3 em adenomas
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Bueno, Cristina Bellotti Formiga. "Polimorfismos dos genes dos receptores de dopamina D2 e de somatostatina subtipos 2 e 5 e resposta ao tratamento medicamentoso de pacientes portadores de adenomas hipofisários." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-18012017-143730/.

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Os adenomas hipofisários podem ser tratados clinicamente com agonistas dopaminérgicos (AD) e/ou ligantes dos receptores de somatostatina (LRS). Alguns estudos apontam para o papel de polimorfismos dos genes DRD2, SSTR2 e SSTR5 na eficácia desses tratamentos clínicos. O objetivo do estudo foi avaliar o papel dos polimorfismos no gene DRD2 em pacientes com prolactinomas (n=118), corticotrofinomas (n=15), adenomas clinicamente não funcionantes (ACNF) (n=35) e somatotrofinomas (n=40), bem como de polimorfismos nos genes SSTR2 e SSTR5 em pacientes com somatotrofinomas (n=88), na resposta ao tratame
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Khattak, Muhammad Nasir Khan [Verfasser]. "Dysregulation of Wnt-β-catenin [Wnt-beta-catenin] pathway in pituitary adenomas and its stimulation by CRH and inhibition by SRIF in ACTH-secreting pituitary adenomas / vorgelegt von Muhammad Nasir Khan Khattak". 2010. http://d-nb.info/1009573152/34.

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Books on the topic "TSH Secreting Pituitary Adenomas"

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Lovett, Alexandra, and Whitney W. Woodmansee. A Young Woman with Infertility. Edited by Angela O’Neal. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190609917.003.0010.

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Prolactinomas are pituitary adenomas that are prolactin-secreting and can lead to galactorrhea, amenorrhea, and infertility. These symptoms often cause women to present earlier than their male counterparts, who are more likely to develop headaches and visual field deficits. Hyperprolactinemia warrants a thorough workup, which should include pregnancy testing, a thyroid-stimulating hormone level, and a thorough review of the patient’s medications. A pituitary-protocoled magnetic resonance image (MRI) with gadolinium should then be performed to look for an adenoma. Prolactinomas can be watched w
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Book chapters on the topic "TSH Secreting Pituitary Adenomas"

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Lania, Andrea Gerardo Antonio, Nazarena Betella, and Davide Milani. "TSH-Secreting Pituitary Adenomas." In Pituitary Disorders of Childhood. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11339-1_8.

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Beck-Peccoz, Paolo, and Giovanni Faglia. "TSH-Secreting Pituitary Adenomas." In Thyroid Diseases. CRC Press, 2024. https://doi.org/10.1201/9781003574293-11.

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Alkabbani, Abdulrahman, Roberto Salvatori, and David S. Cooper. "TSH-Secreting Pituitary Adenoma." In A Case-Based Guide to Clinical Endocrinology. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2059-4_6.

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Dichtel, Laura E. "A Rare Entity: TSH-Secreting Adenoma." In Pituitary Tumors. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-90909-7_9.

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Peverelli, E., E. Giardino, D. Treppiedi, R. Catalano, F. Mangili, and G. Mantovani. "TSH-oma." In Pituitary Adenomas. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-90475-3_8.

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Beck-Peccoz, Paolo, and Luca Persani. "Thyrotropin-Secreting Pituitary Adenomas." In Pituitary Disease. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-1115-1_8.

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Weintraub, Bruce D., Patricia A. Petrick, Neil Gesundheit, and Edward H. Oldfield. "TSH-Secreting Pituitary Tumors." In Frontiers in Thyroidology. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5260-0_10.

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Bonneville, Jean-François, Françoise Cattin, and Jean-Louis Dietemann. "Prolactin-Secreting Pituitary Adenomas." In Computed Tomography of the Pituitary Gland. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70375-1_5.

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Bonneville, Jean-François, Françoise Cattin, and Jean-Louis Dietemann. "ACTH-Secreting Pituitary Adenomas." In Computed Tomography of the Pituitary Gland. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70375-1_9.

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Raffin-Sanson, Marie-Laure, Yves de Keyzer, and Xavier Bertagna. "ACTH Secreting Pituitary Adenomas." In Cushing’s Syndrome. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-1103-8_7.

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Conference papers on the topic "TSH Secreting Pituitary Adenomas"

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Milton, Camille K., Panayiotis E. Pelargos, and Ian F. Dunn. "Cavernous Sinus invasion by Growth-Hormone Secreting Pituitary Adenomas." In Special Virtual Symposium of the North American Skull Base Society. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725512.

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Gill, Amarbir S., Jorgen Sumsion, Jeremiah A. Alt, Michael Karsy, William T. Couldwell, and Sarah T. Menacho. "Intraoperative Alcoholization of the Pituitary Gland Does Not Reduce the Recurrence Rate of Growth Hormone Secreting Pituitary Adenomas." In 31st Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1743952.

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Graffeo, Christopher S., Lucas P. Carlstrom, Salomon Cohen Cohen, Avital Perry, Garret W. Choby, and Jamie J. Van Gompel. "Perioperative Tranexamic Acid for ACTH-Secreting Pituitary Adenomas: Technical Note and Preliminary Cohort Study." In Special Virtual Symposium of the North American Skull Base Society. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0041-1725329.

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Kabir, Aymen S., Zain Peeran, Robert C. Osorio, et al. "Socioeconomic Predictors of Postoperative Remission Status in Acromegalic Patients with Growth Hormone-Secreting Pituitary Adenomas." In 33rd Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2024. http://dx.doi.org/10.1055/s-0044-1780275.

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Cohen, Salomon Cohen, Rima Rindler, Edgar Botello Hernandez, Diane Donegan, Dana Erickson, and Jamie J. Van Gompel. "A Novel Score to Preoperatively Predict Surgical Biochemical Remission in Patients with Growth-Hormone Secreting Pituitary Adenomas." In 32nd Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2023. http://dx.doi.org/10.1055/s-0043-1762104.

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