Academic literature on the topic 'Tuberculosis – history'

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Journal articles on the topic "Tuberculosis – history"

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KOMİLİ, Katriye, and Yağmur BAHAR. "HISTORY OF TUBERCULOSIS." JOURNAL OF INSTITUTE OF ECONOMIC DEVELOPMENT AND SOCIAL RESEARCHES 7, no. 28 (September 28, 2021): 92–100. http://dx.doi.org/10.31623/iksad072807.

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The history of tuberculosis disease dates back to very ancient times. Information from these ages shed light on today's tuberculosis disease. Tuberculosis has been one of the most important diseases that have negatively affected people's lives since ancient times and caused their death. The introduction of tuberculosis by humans occurred when cattle joined their daily habitats. Cattle meat , milk was used to spread the disease rapidly. The only common thing about tuberculosis, which has been referred to by different names throughout the ages, is that its consequences intersect somewhere. Most of the disease is caused by myobacterium Tuberculosis Bacillus. Bacillus was introduced to the world in 1882 through Robert Koach. Tuberculosis causes the most outbreaks in the world after Aids. Past medical history and radiological examinations are of great importance in the diagnosis of the disease. Drug treatment of patients continues for 6 to 8 months, but progress is blocked in the first two to three weeks. The aim of this study is to give general information about the progress of the disease throughout history. Key words: Bacillus , Epidemic, Tuberculosis
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Gowrishankar, NC. "Tuberculosis: Natural History." Pediatric Infectious Disease 1, no. 1 (2019): 4–6. http://dx.doi.org/10.5005/jp-journals-10081-1102.

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Herzog, Basel, H. "History of Tuberculosis." Respiration 65, no. 1 (1998): 5–15. http://dx.doi.org/10.1159/000029220.

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Mülder, Karsten. "Tuberculosis: a case history." Lancet 358, no. 9283 (September 2001): 766. http://dx.doi.org/10.1016/s0140-6736(01)05927-x.

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Pezzella, A. Thomas. "History of Pulmonary Tuberculosis." Thoracic Surgery Clinics 29, no. 1 (February 2019): 1–17. http://dx.doi.org/10.1016/j.thorsurg.2018.09.002.

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Daniel, Thomas M. "The history of tuberculosis." Respiratory Medicine 100, no. 11 (November 2006): 1862–70. http://dx.doi.org/10.1016/j.rmed.2006.08.006.

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Palacios-Sánchez, Leonardo, Ximena Palacios Espinosa, Juan Sebastián Botero Meneses, and Ana María Gómez Carvajal. "Breve historia de la tuberculosis meníngea." Salud Uninorte 39, no. 03 (November 27, 2023): 1196–207. http://dx.doi.org/10.14482/sun.39.03.357.159.

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La tuberculosis es una de las enfermedades más antiguas conocidas por el hombre; una de sus presentaciones clínicas más mortales es la tuberculosis meníngea. La historia de la tuberculosis meníngea abarca una serie de hechos notables, así como un gran número de personas que intervinieron en la descripción de esta enfermedad, su diagnóstico, manejo y la forma en que ha cambiado a lo largo de muchas décadas. Este artículo presenta un panorama de la historia de la tuberculosis meníngea y sus detalles más destacados.
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Hwang, Sook Min, Ji Young Rho, Seung Min Yoo, Hae Kyoung Jung, and Sang Ho Cho. "Atypical pleural tuberculosis presenting as an isolated pleural tuberculoma." Acta Radiologica 53, no. 1 (February 2012): 49–52. http://dx.doi.org/10.1258/ar.2011.110384.

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Pleural tuberculosis is the most common extrapulmonary manifestation of tuberculosis, and is generally characterized by an effusion. The effusion is usually unilateral and residual pleural thickening or calcification is also observed in some cases. Manifestations of multiple pleural tuberculomas without associated effusion and history of tuberculosis or antituberculous therapy are rare and an isolated pleural tuberculoma is exceedingly rare. Herein, we report the first documented case of an isolated pleural tuberculoma, diagnosed by chest CT and pathological findings. Although rare, an isolated pleural tuberculoma should be added to the differential diagnosis of focal nodular pleural tumors, particularly in areas of high tuberculosis prevalence.
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Tellez Bolaños, Vianey Guadalupe, Alejandra Lizbeth Salinas Atriano, Karla Daniela Salgado Guizar, Louis Fernando Robles Fernandez, Francisco Javier Pedraza Murillo, and Roberto Camarena Álvarez. "Cerebral tuberculomas: manifestation of extrapulmonary tuberculosis in an immunocompromised patient. A case report." Iberoamerican Journal of Medicine 5, no. 4 (September 16, 2023): 181–85. http://dx.doi.org/10.53986/ibjm.2023.0030.

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Tuberculosis (Tb) is, currently, the deadliest infectious disease and is caused by organisms of the Mycobacterium tuberculosis complex; the most common clinical manifestation is pulmonary involvement; however, it can also manifest as extrapulmonary affection in immunocompromised patients, especially in patients with human immunodeficiency virus (HIV) chronic infection up to 20% of the cases, despite being on adequate antiretroviral therapy. Within the extrapulmonary manifestations, affection of the central nervous system by hematogenous dissemination occurs in up to 5%, however, the finding of tuberculomas, which is a form of central nervous system involvement, is rare and an important cause in secondary hydrocephalus in these patients. We present the case of a male patient with a history of HIV infection and meningeal tuberculosis, who presented dysfunction of his ventriculoperitoneal shunt and in the imaging study multiple tuberculomas were found, a cerebrospinal fluid study was performed where multi-resistant tuberculosis (MDR) was documented, therefore despite adequate management of Tb, tuberculomas developed.
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Mozhokina, G. N., and A. G. Samoylova. "Clofazimine: History and Perspectives." Tuberculosis and Lung Diseases 99, no. 5 (June 11, 2021): 64–70. http://dx.doi.org/10.21292/2075-1230-2021-99-5-64-70.

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The review analyses 47 publications that follow the pathway of clofazimine from its discovery to recognition as a Group B drug for treatment of multiple drug resistant tuberculosis. It describes its mechanism of action and effects on Mycobacterium tuberculosis, pharmacokinetics, and safety parameters.
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Dissertations / Theses on the topic "Tuberculosis – history"

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Сміянов, Владислав Анатолійович, Владислав Анатольевич Смиянов, Vladyslav Anatoliiovych Smiianov, Світлана Володимирівна Павличева, Светлана Владимировна Павлычева, Svitlana Volodymyrivna Pavlycheva, Ольга Іванівна Сміянова, Ольга Ивановна Смиянова, Olha Ivanivna Smiianova, and A. V. Kovchun. "History of tuberculosis." Thesis, Видавництво СумДУ, 2012. http://essuir.sumdu.edu.ua/handle/123456789/27490.

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Al-Mouaiad, Al-Azem Assaad. "Epidemiology of tuberculosis in Manitoba, 1992-1997." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0002/MQ45018.pdf.

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Knowling, William Ronald. "Ignorant, dirty, and poor, the perception of tuberculosis in Newfoundland, 1908-1912." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq23151.pdf.

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Dunsford, Deborah. "Seeking the prize of eradication : a social history of tuberculosis in New Zealand from World War Two to the 1970s /." e-Thesis University of Auckland, 2008. http://hdl.handle.net/2292/2932.

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Mohatli, Matema Constance. "Determination of heteroresistant mychobacterim tubeculosis strains and their association with patients tuberculosis treatment history in Limpopo Province." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1568.

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Thesis (M. Sc. (Medical Sciences)) -- University of Limpopo, 2015
Tuberculosis (TB) patients may have mixed infections with both drug-susceptible and drug-resistant Mycobacterium tuberculosis (MTB) strains. This phenomenon termed heteroresistance presents a challenge TB management and is considered a preliminary stage to full resistance. Heteroresistance is more likely to occur in high TB incidence areas and in chronic patients as they have more opportunity to become infected with various strains of TB and has been proven to occur in new cases, treatment failure and relapse. Methods: Sputum samples were collected from new consulting and hospitalised patients who were on treatment for MDR TB. A total of 231 samples were run on MTBDRplus to determine heteroresistance of Mycobacterium tuberculosis to isoniazid and rifampicin. To determine heteroresistance to second-line drugs, 91 samples were run on MTBDRsl. Nineteen (19) samples that were heteroresistant to 2nd line drugs were subjected to spoligotyping to determine the families/lineages they belonged to. Results: A total of 66 were confirmed as Mycobacterium tuberculosis complex by the line probe assays. Out of the 66 MTBC, rifampicin resistance was found in 22 (10%) and 44 (19%) were reported susceptible. Isoniazid resistance was found in 39 (17%) and 27 (12%) were reported susceptible. Of the 66 MTBC positive samples, moxifloxacin resistance was found in 33 (16%) and 14 (7%) were reported susceptible. Kanamycin resistance was found in 17 (8%) and 30 (14%) were reported susceptible. Ethambutol resistance was found in 25 (12%) and 22 (10%) were reported susceptible. Heteroresistance was evident in 22 (10%) samples for the first-line and in 23 (11%) for the second-line drugs. Results of a total of 19 heteroresistant samples subjected to spoligotyping when compared to those in the international spolDB4 database indicated that 4 of them matched existing shared spoligotype international types, 15 were unknown (orphans). Eighteen (18) of 19 heteroresistant samples subjected to spoligotyping were also MDR. Fourteen of the samples that were resistant to both RIF and INH were orphans. Of the 14 MDR, 3 samples belonged to clades T1, T-H37RvV817 and LAM 3 with SITs: 879, 568 and 2301, respectively. One sample with SIT 1196 had an unknown clade was resistant to RIF but susceptible to INH. Conclusion: This study has shown that heteroresistance remains an important phenomenon in clinical tuberculosis, especially in highly endemic areas. According to the current study, heteroresistance was associated more with recurrent cases who are on initiation or continuation phase than new cases and a larger percentage of heteroresistance was reported in second-line drugs than there is in first-line drugs. The T1 genotype was found to be predominant amongst recurrent cases. The LAM3 and T-H37RvV817 lineages were found amongst the new cases. In the present study there was no significant association between heteroresistance and the patient’s treatment history as indicated by a P-value of 0.473 and between heteroresistance and spoligotype families (P-value, 0.991). The predominance of orphan SITs and unknown clades followed by non-Beijing strains in the study may be due to the migration of carriers from the neighboring countries as the Limpopo Province is flanked by Botswana, Zimbabwe and Mozambique. Further studies with larger numbers of patients should focus on the prevalence to associate heteroresistance with patients‟ treatment history and establish the contributing MTBC strain lineages.
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Gallagher, John. "The Natural History of Spontaneous Tuberculosis in Wild badgers." Thesis, Royal Veterinary College (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522203.

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Cronje, Gillian Charles. "Pulmonary tuberculosis in England and Wales, 1851-1910." Thesis, London School of Economics and Political Science (University of London), 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338487.

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Muller, Romy. "Tuberculosis throughout history : ancient DNA analyses on European skeletal and dental remains." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/tuberculosis-throughout-history-ancient-dna-analyses-on-european-skeletal-and-dental-remains(15084f13-8e8d-4f5f-9806-dc9c99ad2dac).html.

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Tuberculosis (TB) has killed millions of people throughout history and still isone of the leading causes of death. Since the early 1990s, ancient DNA(aDNA) research has made considerable contributions to the study of thisinfectious disease in the past. While early studies used polymerase chainreactions (PCRs) solely to identify the TB-causing organisms, namely theMycobacterium tuberculosis complex (MTBC), later approaches extended thefocus to assign the actual disease-causing species or strains of the MTBCbut were either directed at single or few individuals or only provided few data. This research project has screened a large set of European skeletaland dental samples from individuals of the 1st–19th centuries AD for IS6110,an insertion sequence believed to be specific to the MTBC, and has identifieda number of individuals that may indeed have suffered from TB. Reports ofIS6110-like elements in other mycobacteria, however, challenge thesuitability of IS6110 for detecting MTBC. Two sequences similar but notidentical to IS6110 were revealed from several of the samples analysed,supporting the proposal that IS6110 should not serve as the sole target foridentifying MTBC from archaeological material. It cannot be establishedwhere these sequences derive from, but application of a MycobacteriumspecificPCR and targeting of genomic regions of the MTBC that containsingle nucleotide polymorphism (SNPs) indicate that at least some of thesamples contain a range of unknown, most likely environmental, bacterialand/or mycobacterial species. Yet, screening for IS6110 together with thedetection of large sequence polymorphisms (LSPs) and SNPs in othergenomic regions has identified eight individuals to unambiguously containMycobacterium tuberculosis aDNA. Apart from one individual which wasrecovered from Northern France, these skeletons derived from Britisharchaeological excavation sites. The SNP and LSP results enabled theallocation of infecting MTBC strains into various classification systemsreported in clinical literature and revealed that M. tuberculosis strains variedthroughout different time periods, thereby mainly confirming evolutionarypathways suggested in previous studies. Additionally, it was found thatdistinct strains co-existed temporally, and maybe even spatially, in Britainand that at least one individual harboured two different MTBC strains,suggesting a mixed infection. Application of next generation sequencingenabled one of the 19th century strains from Britain to be characterised ineven more detail, revealing closest similarity to a M. tuberculosis strainisolated at the beginning of the 20th century in North America.
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Richner, Sharon M. "The measurement of genetic diversity in mycobacterium tuberculosis using random amplified polymorphic DNA profiling." Thesis, Rhodes University, 2000. http://hdl.handle.net/10962/d1004068.

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Mycobacterium tuberculosis has caused a resurgence in pulmonary disease in both developed and developing countries in recent times, particularly amongst people infected with the human immunodeficiency virus. The disease has assumed epidemic proportions in South Africa and in the Eastern Cape Province in particular. Of further concern is the isolation of increasing numbers of multiply drug resistant strains. Knowledge of the genetic capability of this organism is essential for the successful development of novel antibiotics and vaccines in an attempt to bring the global pandemic under control. Measurement of the genetic diversity of the organism may significantly contribute to such knowledge, and is of vital importance in monitoring epidemics and in improving treatment and control of the disease. This will entail answering a number of questions related to the degree of genetic diversity amongst strains, to the difference between urban and rural strains, and between drug resistant and drug sensitive strains, and to the geographical distribution of strains. In order to establish such baseline information, RAPD profiling of a large population of isolates from the western and central regions of the Eastern Cape Province was undertaken. A smaller number of drug resistant strains from a small area of KwaZulu-Natal were also analysed, with a view to establishing the genetic difference between strains from the two provinces. Cluster analysis, analysis of molecular variance and Geographical Information Systems technology were used to analyse the RAPD profiles generated. An unexpectedly high degree of genetic diversity was detected in strains from both provinces. While no correlation was seen between genetic diversity and either urban-rural situation or geographical location, a small degree of population structure could be correlated with drug resistance in the Eastern Cape. Furthermore, a significant degree of population structure was detected between strains from the two provinces, although this was still within the parameters for conspecific populations. Future work is necessary to further characterise strains from rural areas of both provinces, as well as from the eastern region of the Eastern Cape in an attempt to pinpoint the cause of the separation of the provincial populations.
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McFarlane, Neil Munro. "Tuberculosis in Scotland, 1870-1960." Thesis, University of Glasgow, 1990. http://theses.gla.ac.uk/2041/.

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Books on the topic "Tuberculosis – history"

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Gyögy, Pálfi, ed. Tuberculosis: Past and present = Tuberculosis: múlt és jelen = Tuberculose: passé et présent. [S.l.]: Golden Books/TB Foundation, 1999.

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ed, Pálfi György, ed. Tuberculosis past and present: Tuberculosis múlt és jelen : tuberculose : passé et présent. Szeged: Golden Book and Tuberculosis Foundation, 1999.

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McPartland, Randall. Tuberculosis. New York: Cavendish Square, 2016.

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Filho, Cláudio Bertolli. História social da tuberculose e do tuberculoso: 1900-1950. Rio de Janeiro, RJ: Editora Fiocruz, 2001.

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Rothman, Sheila M. Living in the shadow ofdeath: Tuberculosis and the social experience of illness in American history. New York: BasicBooks, 1994.

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Below the magic mountain: A social history of tuberculosis in twentieth-century Britain. Oxford [Oxfordshire]: Clarendon Press, 1988.

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Rothman, Sheila M. Living in the shadow of death: Tuberculosis and the social experience of illness in American history. Baltimore: Johns Hopkins University Press, 1995.

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Dormandy, Thomas. The white death: A history of tuberculosis. London: Hambledon Press, 1999.

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Chrétien, Jacques. Tuberculosis: The illustrated history of a disease. Paris: International Union Against Tuberculosis, 1998.

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Gutmann, Rosenkrantz Barbara, ed. From consumption to tuberculosis: A documentary history. New York: Garland Pub., 1993.

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Book chapters on the topic "Tuberculosis – history"

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Daniel, Thomas M., Joseph H. Bates, and Katharine A. Downes. "History of Tuberculosis." In Tuberculosis, 13–24. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555818357.ch2.

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Pesanti, Edward L. "A history of tuberculosis." In Tuberculosis, 5–19. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-2869-6_2.

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Loddenkemper, Robert, and John F. Murray. "History of Tuberculosis." In Essential Tuberculosis, 3–9. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66703-0_1.

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Roberts, Charlotte A., and Jane E. Buikstra. "The History of Tuberculosis from Earliest Times to the Development of Drugs." In Clinical Tuberculosis, 3–15. Sixth edition. | Boca Raton, FL : CRC Press/Taylor & Francis Group, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9781351249980-1.

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Kumar, Antriksh, and Harshal S. Mandavdhare. "Abdominal Tuberculosis: A Brief History." In Tuberculosis of the Gastrointestinal system, 3–8. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9053-2_1.

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Haldar, Pranabashis. "The Natural History of TB and Latent Infection." In Tuberculosis in Clinical Practice, 1–14. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75509-6_1.

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Martini, M. "History of Bone and Joint Tuberculosis." In Tuberculosis of the Bones and Joints, 3–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-61358-6_2.

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Nomori, Hiroaki. "History of Segmentectomy for Lung Tuberculosis." In Anatomical Segmentectomy for Lung Cancer, 3–4. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-5857-3_1.

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Wang, Lixia. "Modern History of Tuberculosis Control in China." In Handbook of Global Tuberculosis Control, 3–14. Boston, MA: Springer US, 2017. http://dx.doi.org/10.1007/978-1-4939-6667-7_1.

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Hakosalo, Heini. "The Ill(s) of the Nation: The Experience of Tuberculosis in Finland from the 1920s to the 1970s." In Palgrave Studies in the History of Experience, 241–66. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-69882-9_10.

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AbstractHeini Hakosalo makes use of an extensive collection of written, unpublished tuberculosis-related illness narratives to analyze the experience of tuberculosis and tuberculosis sanatoria “from below” within the context of twentieth-century Finland. Hakosalo argues that by linking their personal illness histories to national history, the authors could give a sense of purpose and meaning to their personal losses and suffering. At the same time, their testimonies stood as a contribution, however modest, to the national knowledge-community. She distinguishes three narrative strands that allowed the authors to assimilate their personal illness with the collective ills of the nation: histories of tuberculosis as stories of progress, stories of war, and stories of belonging.
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Conference papers on the topic "Tuberculosis – history"

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Dunga, Lucas Medeiros, Renner Cassio Nunes de Lucena, Matheus Araújo de Medeiros, Brendo Bezerra Benvenuto, Tiago Lameque de Sousa e. Silva, Maria Eduarda Medeiros Martins, Fabricia dos Santos Almeida, et al. "Cerebral tuberculoma as a differential diagnosis for extraaxial lesions in immunocompetent patient: case report." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.630.

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Introduction: Cerebral tuberculomas are a rare and serious form of tuberculosis, representing 0.2% of intracranial expansive processes. In the absence of conclusive diagnostic tests, doctors often make treatment decisions based on clinical judgment, cerebrospinal fluid (CSF) profile, and radiological findings. Magnetic resonance imaging (MRI) commonly shows discrete lesions with ring enhancement, with perilesional edema, being a relevant differential diagnosis in ring lesions, as their clinical and imaging can mimic brain tumors. The aim to report a case of cerebral tuberculoma in an immunocompetent patient. This is a case report study. The information of this work was obtained through review of the medical record. Case report: G.L.F, female, 26 years old, immunocompetent, with a history of generalized tonic-clonic seizure. MRI showed a right temporal extra-axial lesion, with heterogeneous contrast enhancement and adjacent dural thickening, associated with vasogenic edema. CSF was collected for investigation of inflammatory disease, without any significant findings. Excisional biopsy for anatomopathological analysis revealed an epithelioid granulomatous process (complete tuberculoid granulomas) with central caseous necrosis. Based on clinical, laboratory, and imaging data correlation, the conclusion was reached that it was a cerebral tuberculoma. Treatment followed the standard tuberculosis regimen for one year. Conclusion: Mycobacterium tuberculosis infection in the central nervous system, manifested as tuberculoma, although extremely rare, should be considered as a differential diagnosis for expansive brain lesions, especially in regions with a higher prevalence of the disease.
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Ben Saad, Soumaya, Nourelhouda Mbarek, Ines Mejri, and Fatma Tritar. "Risk factors for tuberculosis in patients with history of incarceration." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa3871.

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Millet, Juan-Pablo, Angels Orcau, Laia Fina, Antonio Moreno, Lucia Bano, Pilar Gorrindo, Eva Masdeu, and Joan A. Caylà. "Associated Factors To Tuberculosis History In Current Patients In A Big European City." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3264.

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Jegal, Y., K. Seo, D. Yang, H. Lee, and J. Ahn. "The Significance of Whole Blood Interferon-gamma Assay in Patients with History of Pulmonary Tuberculosis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4098.

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Aguslina, Fazidah, and Wirsal Hasan. "Effects of Contact History and Family Income on the Risk of Pulmonary Tuberculosis in Padangsidimpuan, North Sumatera." In The 4th International Conference on Public Health. Masters Program in Public Health Universitas Sebelas Maret, 2018. http://dx.doi.org/10.26911/theicph.2018.01.40.

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Chen, Yen-Fu, Hsin-Han Hou, Jung-Yien Chien, Chin-Chung Shu, Shih-Lung Cheng, Hao-Chien Wang, and Chong-Jen Yu. "History of pulmonary tuberculosis was associated with lung microbiome change in patients with chronic obstructive pulmonary disease." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.554.

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Fahrezi, Chattrin, and Rezania Asyfiradayati. "History of Household Contact, Maternal Domestic Hygiene, and Their Associations with the Risk of Tuberculosis in Children." In The 8th International Conference on Public Health 2021. Masters Program in Public Health, Universitas Sebelas Maret, 2021. http://dx.doi.org/10.26911/ab.epidemiology.icph.08.2021.12.

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Haile, B. W., C. B. Sherman, R. A. Kebede, H. Y. Ahmed, and East African Training Initiative Pulmonary and critical care. "An Unusual Case of Squamous Cell Carcinoma Presenting After a 20 Year History of Pulmonary Tuberculosis Treatment." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3398.

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Pompermaier, Carolina, Cassio Fernando Paganini, Willian Ely Pin, Mateus Xavier Schenato, and Tales Antunes Franzini. "TUBERCULOUS LYMPHADENITIS: A CASE REPORT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1079.

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Tuberculous lymphadenitis is the infection of lymph nodes by Mycobacterium tuberculosis. In the USA, about 8.5% of the cases of tuberculosis (TB) were characterized by lymphadenitis. The peak occurs between 30 and 40 years of age, primarily in women. Extrapulmonary TB is usually diagnosed in immunocompromised patients. The diagnosis is given by positivity in the AFB (Alcohol-Acid Resistant Bacillus) in Ziehl-Neelsen staining by sample collected by fine-needle puncture or lymph node excision. Cyto and histological analysis demonstrate epithelial cells, caseous necrosis, and necrotic cells. Such findings, added to the presence of langerhan’s giant cells, favor the diagnosis of TB even in AFB and/or negative cultures. Mantoux test is usually positive. Culture is the definitive diagnosis. Surgical excision should be reserved for diagnostic in HIV-seronegative patients. The picture involves progressive and painless growth of the lymph node chain, which may reach 8–10 cm. One-sidedness occurs in most cases. Peripheral lymphadenopathy is common among breast pathologies. The case is unusual due to the suspicion of axillary lymphadenopathy being of neoplastic origin from compatible histopathological and immunohistochemical analysis of a core biopsy. However, after the excision of lymph node clusters, histopathology showed the absence of tumor and metastatic cells. The analysis of slides with palisaded epithelioid granulomas and caseous necrosis, however, is consistent with TB lymphadenopathy. However, some points made such a verdict difficult such as negative fungal and alcohol-acid-resistant bacilli (AFB) research, as well as the presence of lymphadenopathy in the contra lateral armpit and inguinal chains, the absence of cervical lymph node enlargement and any other suggestive symptoms of associated extra-pulmonary tuberculosis. The other possibilities include non-TB mycobacteria, Bartonella sp, fungi (Histoplasma) and parasites (Toxoplasma gondii), lymphomas, sarcomas, metastatic carcinomas, sarcoidosis, cat-scratch disease, and congenital lymphatic malformations. Treatment should be performed after the confirmation of diagnosis or when susceptibility to antimicrobials is suspected (empirical treatment). In the first 2 months of the treatment, Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol were used; followed by 4 months of Isoniazid and Rifampicin. The guidelines recommend surgical excision only in unusual situations, such as therapeutic failure. Ulceration, fistulas, and abscesses are complications. A 26-year-old female, nursing mother, breastfeeding only through the left breast due to a history of clefts in the right breast and with a family history of breast cancer, was referred to the breast service due to the appearance of painless nodules in her right armpit with progressive growth. Previously, she had been treated with Amoxicillin and Azithromycin, with no change in her condition. On physical examination, a lymph node aggregate was found in the right axilla. She underwent ultrasound and mammography examinations, which showed lymph nodes, measuring 2.9×1.3, 2×1.4, and 1.3×0.8 cm in the right armpit, compatible with BI-RADS IVc classification. It was decided to suppress lactation with Cabergoline and proceed with core biopsy, which showed fibrofatty tissue with chronic inflammation and epithelioid granuloma in the anatomopathological examination, and immunohistochemistry showed the markers CKM (AE1/AE3/PCK26), GATA-3 (L50-823), and Mamoglobin A (304-1A5) all negative, compatible with metastasis of primary breast cancer. After discussion, it was decided to proceed with the removal of the fused lymph nodes at level I of the right axilla. The histopathological diagnosis showed epithelioid and palisade granulomas with caseous necrosis in the lymph nodes, with negative BAAR research. Also, laboratory examinations for syphilis, HIV, HCV, and HBV were all negative and a clean chest x-ray. This patient will start treatment for TB.
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Poon, J., E. Eisenberg, T. J. Harkin, and D. Steiger. "Unusual Presentation of Mycobacterium Tuberculosis in an Asymptomatic Patient with a PET Avid Mass and History of Silica Exposure." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a2179.

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Reports on the topic "Tuberculosis – history"

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Jangid, Ajay, Anurag Mishra, Rachit Raj, Sumit Kumar, Priyanka Munjal, and Neha Pandey. Chronic Myeloid Leukemia (CML) as Surgical Emergency. Science Repository, March 2024. http://dx.doi.org/10.31487/j.ajscr.2024.01.02.

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Ileal perforation peritonitis is a critical surgical emergency often encountered in developing countries, commonly associated with typhoid fever, tuberculosis, trauma, and non-specific enteritis. This case report presents a unique instance of nonspecific enteritis associated with chronic myeloid leukemia (CML). A 16-year-old girl with a history of pulmonary tuberculosis presented with symptoms, leading to the diagnosis of ileal perforations and CML. Surgical intervention involved ileal resection and double barrel ileostomy. The postoperative course included complications and chemotherapy with imatinib, demonstrating the challenges and management strategies in such cases. The discussion emphasizes the varied aetiologies of non-traumatic ileal perforation in different regions and sheds light on the rare gastrointestinal manifestations of CML. Notably, this report underscores the significance of prompt imatinib therapy in controlling CML while highlighting the need for vigilant monitoring and dose adjustments due to chemotherapy-related adverse effects.
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Interventions to reduce HIV/AIDS stigma: What have we learned? Population Council, 2001. http://dx.doi.org/10.31899/hiv2001.1001.

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Stigma is a common human reaction to disease. Throughout history many diseases have carried considerable stigma, including leprosy, tuberculosis, cancer, mental illness, and many sexually transmitted diseases. HIV/AIDS is only the latest disease to be stigmatized. This paper reviews 21 interventions that have explicitly attempted to decrease AIDS stigma both in the developed and developing countries and 9 studies that aim to decrease stigma related with other diseases. The studies selected met stringent evaluation criteria in order to draw common lessons for future development of interventions to combat stigma. This paper assesses published and reported studies through comparison of audiences, types of interventions, and methods used to measure change. Target audiences include both those living with or suspected of living with a disease and perpetrators of stigma. All interventions reviewed target subgroups within these broad categories. Types of programs include general information-based programs, contact with affected groups, coping skills acquisition, and counseling approaches. A limited number of scales and indices were used as indicators of change in AIDS stigma.
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