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Journal articles on the topic 'Tuberculosis in animals. [from old catalog]'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2025

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1

Achtman, Mark. "How old are bacterial pathogens?" Proceedings of the Royal Society B: Biological Sciences 283, no. 1836 (2016): 20160990. http://dx.doi.org/10.1098/rspb.2016.0990.

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Only few molecular studies have addressed the age of bacterial pathogens that infected humans before the beginnings of medical bacteriology, but these have provided dramatic insights. The global genetic diversity of Helicobacter pylori , which infects human stomachs, parallels that of its human host. The time to the most recent common ancestor (tMRCA) of these bacteria approximates that of anatomically modern humans, i.e. at least 100 000 years, after calibrating the evolutionary divergence within H. pylori against major ancient human migrations. Similarly, genomic reconstructions of Mycobacte

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Roberts, A. D., and Ian M. Orme. "CD95 Expression in Aged Mice Infected with Tuberculosis." Infection and Immunity 66, no. 10 (1998): 5036–40. http://dx.doi.org/10.1128/iai.66.10.5036-5040.1998.

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ABSTRACT The interaction between CD95 and its ligand is an important homeostatic mechanism that leads to the induction of apoptosis in activated T cells. In view of recent evidence that this pathway might be defective in aged mice, this study investigated CD95 expression on T cells in old mice activated by infection with Mycobacterium tuberculosis. The results of the study do not support the hypothesis that CD95 is poorly expressed on CD4 T cells from old mice; instead, it was found that similar numbers of T cells from young and old mice expressed CD95, with the intensity of expression if anyt

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Zmak, Ljiljana, Marija Gomercic Palcic, Mihaela Obrovac, et al. "First Confirmed Case of Zoonotic Transmission of RR-TB from a Dog to a Human, a Neglected Mode of Mycobacterium tuberculosis Infection—Case Report and Review of the Literature." Pathogens 14, no. 7 (2025): 684. https://doi.org/10.3390/pathogens14070684.

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Mycobacterium (M.) tuberculosis mostly spreads from active tuberculosis (TB) patients to human contacts, although human-to-animal and animal-to-human transmission has been described. Here, we present a rare case of rifampicin-resistant tuberculosis (RR-TB) transmission from a companion dog to its owner, highlighting the zoonotic potential of the pathogen. Namely, a 37-year-old Croatian man was diagnosed with RR-TB, with whole-genome sequencing analysis revealing a close genetic link to the strain isolated from his dog, which had died of miliary TB six years earlier. This case emphasizes the co

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Orme, I. M. "Aging and immunity to tuberculosis: increased susceptibility of old mice reflects a decreased capacity to generate mediator T lymphocytes." Journal of Immunology 138, no. 12 (1987): 4414–18. http://dx.doi.org/10.4049/jimmunol.138.12.4414.

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Abstract This study employed an experimental mouse model of Mycobacterium tuberculosis infection to investigate the effects of aging on T cell-mediated protective cellular immunity. It was found that although mice of 3 to 18 mo of age were fully resistant to a standard immunizing dose of Mycobacterium tuberculosis, progressive mortality was observed in old (24 to 28 mo) mice. Death of these older animals was associated with an inability to contain or to eliminate the mycobacterial infection in the spleen and liver, and with an inability to prevent the progressive growth of the infection in the

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Srinivasan, Sreenidhi, Gareth Jones, Maroudam Veerasami, et al. "A defined antigen skin test for the diagnosis of bovine tuberculosis." Science Advances 5, no. 7 (2019): eaax4899. http://dx.doi.org/10.1126/sciadv.aax4899.

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Bovine tuberculosis (bTB) is a major zoonotic disease of cattle that is endemic in much of the world, limiting livestock productivity and representing a global public health threat. Because the standard tuberculin skin test precludes implementation of Bacille Calmette-Guérin (BCG) vaccine–based control programs, we here developed and evaluated a novel peptide-based defined antigen skin test (DST) to diagnose bTB and to differentiate infected from vaccinated animals (DIVA). The results, in laboratory assays and in experimentally or naturally infected animals, demonstrate that the peptide-based

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Ocepek, M., M. Pate, M. Zolnir-Dovc, and Z. Cvetnic. "Tuberculosis in cattle caused by IS901+ Mycobacterium avium subsp. avium – a case report." Veterinární Medicína 48, No. 1 - 2 (2012): 47–50. http://dx.doi.org/10.17221/5749-vetmed.

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In a small cattle herd an eight-year-old cow showed a reaction to bovine tuberculin in two consecutive skin tests. The animal showing clinical signs related to tuberculosis was slaughtered for diagnostic purpose. The lungs were completely covered with disseminate tubercles of different sizes and the mediastinal lymph nodes were enlarged. Pneumonia granulomatosa tuberculosa and lymphadenitis hyperplastica chronica were diagnosed histologically. Mycobacterium avium subsp. avium of IS901+ and IS1245+ genotype was isolated from lungs and from the lymph node. Six weeks after the affected animal has

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Male Here, Rischi Robinson, Eoin Ryan, Philip Breslin, Klaas Frankena, and Andrew William Byrne. "Revisiting the relative effectiveness of slaughterhouses in Ireland to detect tuberculosis lesions in cattle (2014–2018)." PLOS ONE 17, no. 10 (2022): e0275259. http://dx.doi.org/10.1371/journal.pone.0275259.

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Slaughterhouse or meat factory surveillance to detect factory lesions (FL) at slaughter is an important part of the bovine tuberculosis (bTB) eradication program in Ireland. The objective of this study was to quantify the effectiveness of Irish slaughterhouses or factories in submitting FL and the proportion of those submitted FL confirmed as being due to bTB in slaughtered cattle, and to identify and quantify the association of risk factors at animal, herd, and factory level with FL submission and confirmation. The data consisted of 6,611,854 animals slaughtered in Irish factories from 2014 t

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Zanwa, A. I., C. A. Agada, and I. I. Luga. "Prevalence and risk factors associated with bovine tuberculosis in the southern zone of Nasarawa State, north-central Nigeria." Sokoto Journal of Veterinary Sciences 21, no. 4 (2024): 169–76. http://dx.doi.org/10.4314/sokjvs.v21i4.2.

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A cross-sectional study was conducted on 500 grazing cattle under a pastoral production system in the southern zone of Nasarawa state, North-Central Nigeria to determine the prevalence and risk factors associated with bovine tuberculosis using a Single intradermal Comparative Tuberculin Test (SCITT) from April 2019 to February 2020. The total number of animals with bTB was 46 (9.2%) and the results were significantly higher in older animals between 5-6years (OR: 7.4; CI: 1.54-35.4; P=0.000) and in those animals that were ≥ 7 years (OR: 5.7; CI: 1.24-25-9; P=0.00) old and likely at risk of havi

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Courtin, Francois, Michel Huerre, Janet Fyfe, Paul Dumas, and Maria L. Boschiroli. "A case of feline leprosy caused by Mycobacterium lepraemurium originating from the island of Kythira (Greece): diagnosis and treatment." Journal of Feline Medicine and Surgery 9, no. 3 (2007): 238–41. http://dx.doi.org/10.1016/j.jfms.2006.11.007.

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A 2-year-old, 4 kg, healthy, domestic shorthair female cat presented with ulcerated subcutaneous nodules on the commissures of its mouth. The cat was negative for feline leukaemia virus and feline immunodeficiency virus. Skin mycobacteriosis was diagnosed after detection of numerous acid-fast bacilli in Ziehl Neelsen-stained smears from the ulcers. Feline leprosy was suspected following preliminary polymerase chain reaction results: positive for Mycobacterium genus but negative for Mycobacterium tuberculosis and Mycobacterium avium complexes. Mycobacterium lepraemurium was later identified fol

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Fernández, Miguel, Marcos Royo, Miguel Fuertes, et al. "Effects of Paratuberculosis Vaccination at Different Ages in a Dairy Goat Herd: A 2-Year Follow-Up." Animals 12, no. 22 (2022): 3135. http://dx.doi.org/10.3390/ani12223135.

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Vaccination could be considered as an effective method for paratuberculosis control, although controversial, with a need for investigation in some aspects. The objective of this study was to evaluate the effect of vaccination, depending on the age of the animals, on their immune response, the reduction of paratuberculosis cases, mortality and culled animals in a commercial dairy herd. Goats from three different ages were immunized with the inactivated Gudair® vaccine. Peripheral antibody and IFN-γ output were evaluated for 21 months post-vaccination (mpv) and intradermal skin tests (IDSTs) for

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Kwestan N. A., R. R. Sulaiman, and H. O. Dyary. "IN VITRO INVESTIGATION OF BOVINE TUBERCULOSIS IN SULAYMANIYAH, IRAQ." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 56, no. 1 (2025): 423–29. https://doi.org/10.36103/eywrm293.

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This study was conducted to detect bovine tuberculosis (TB) in Sulaymaniyah, Kurdistan Region of Iraq, using gamma interferon assay (GIA), and determine the prevalence in the governorate. The study was carried out among three groups of cattle: calves aged 6–12 months, heifers 13–24 months, and cows aged above two years. Bovine TB was detected by an indirect enzyme-linked immunosorbent assay (ELISA) using the GIA, carried out on 404 cattle within the target population (31173) from different districts around the governorate. A TB prevalence rate of 8.9% was detected. The highest prevalence rate

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Pérez de Val, Bernat, Sergio López-Soria, Miquel Nofrarías, et al. "Experimental Model of Tuberculosis in the Domestic Goat after Endobronchial Infection with Mycobacterium caprae." Clinical and Vaccine Immunology 18, no. 11 (2011): 1872–81. http://dx.doi.org/10.1128/cvi.05323-11.

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ABSTRACTCaprine tuberculosis (TB) has increased in recent years, highlighting the need to address the problem the infection poses in goats. Moreover, goats may represent a cheaper alternative for testing of prototype vaccines in large ruminants and humans. With this aim, aMycobacterium capraeinfection model has been developed in goats. Eleven 6-month-old goats were infected by the endobronchial route with 1.5 × 103CFU, and two other goats were kept as noninfected controls. The animals were monitored for clinical and immunological parameters throughout the experiment. After 14 weeks, the goats

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Karimov, Tahir, Leyla Ahmadli, Sevinj Rajabova, and Ayaz Mammadov. "The “Sanitary” Role of the Necrophagous Birds in the Ecosystems." BIO Web of Conferences 151 (2025): 01013. https://doi.org/10.1051/bioconf/202515101013.

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The objective of the research work was to study the “sanitary” role of necrophagous birds (Gyps fulvus, Aegypius monachus, Gypaetus barbatus, Neophron percnopterus) in the Azerbaijani part of the Lesser Caucasus. For this purpose, monitoring was conducted in the Korchay State Nature Reserve and adjacent territories in June 2013. During this period, we identified carcasses of animals that had died from various causes, including those carrying infectious diseases. In total, 28 carcasses of domestic (n=5) and wild (n=5) mammals were found. Among these, 13 carcasses were associated with six infect

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Silva, Ediane, Michelle Reis, W. Ray Waters, Brian Nonecke, Ana Paula Junqueira-Kipnis, and Don Mark Estes. "IMMUNOSUPPRESSIVE CYTOKINE PRODUCTION IN BOVINE VITAMIN A -DEFICIENT CHALLENGED WITH M. BOVIS (43.13)." Journal of Immunology 184, no. 1_Supplement (2010): 43.13. http://dx.doi.org/10.4049/jimmunol.184.supp.43.13.

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Abstract It has been shown that vitamin A could induce T regulatory (Treg) cells, especially in the tuberculosis infection. One of action mechanism these cells are due the cytokines presence as IL-10, TGF-β and FOXP3. In this study was evaluated the production of these cytokines in vitamin A sufficient and deficient tuberculosis calves. Animals of 1 - 2 weeks old from a TB-free source were fed with a diet containing or not vitamin A. PBMC were cultivated with or without PPD, and then cells were stained for CD8, WC1γδ T and NK cells receptors for flow cytometry analysis. The cells culture super

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Martínez, Emilia Irina, Fabiana Cipolini Galarza, Nolly María Monzón, et al. "Diagnosis of tuberculosis in buffaloes in Argentina: intradermoreaction, compatible lesions and bacteriological culture." Revista Científica de la Facultad de Ciencias Veterinarias 33, Suplemento (2023): 231–32. https://doi.org/10.52973/rcfcv-wbc088.

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Bovine tuberculosis is a zoonotic disease distributed worldwide and present in Argentine herds. In Argentina, bovine and buffalo cattle are under a tuberculosis control and eradication program, which includes tuberculin purified protein derivative bovine (PPDB) diagnosis and slaughter of positive reagents. The use of this control tool is controversial in buffaloes. The aim of this study is to generate information about buffalo tuberculosis in Corrientes,Argentina, through evaluation of field diagnostic test performance, detection of tuberculosis compatible lesions in previously tuberculinized

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Alberti, Taina S., Fabio Raphael P. Bruhn, Rosimeri Zamboni, et al. "Epidemiological analysis of bovine tuberculosis in the southern region of Rio Grande do Sul from 2000 to 2015." Pesquisa Veterinária Brasileira 40, no. 2 (2020): 77–81. http://dx.doi.org/10.1590/1678-5150-pvb-6406.

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ABSTRACT: Bovine tuberculosis (BTB) is an infectious and zoonotic disease with socioeconomic importance, responsible for economic losses in livestock due to the decrease in animal productivity, mortality, bovine carcass condemnation and restriction on exportations. The objective of the present study was to evaluate the epidemiological aspects of this disease through a descriptive analysis and time series of cases of bovine tuberculosis diagnosed at the Laboratório Regional de Diagnóstico (LRD) of the Faculdade de Medicina Veterinária, Universidade Federal de Pelotas (UFPel) from 2000 to 2015.

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Agada, C. A., J. Mohammed, A. E. J. Okoh, and A. J. Ogugua. "Occurrence of tuberculosis and predictors of zoonotic TB transmission among livestock workers in Lafia, Nigeria." Sokoto Journal of Veterinary Sciences 17, no. 4 (2020): 35–50. http://dx.doi.org/10.4314/sokjvs.v17i4.5.

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Although tuberculosis (TB) is prevalent in domestic animals and man in Nigeria, prevalence and zoonotic tuberculosis (ZTB) predictors information among livestock workers in Lafia, is scarce. This study determined TB prevalence and ZTB predictors among livestock workers in the town.In a cross-sectional study, sputum samples from 96 participants selected by systematic random sampling (56 abattoir workers and 40 cattle herdsmen and marketers), to whom semi-structured questionnaire was issued, were tested with Ziehl Neelson stain. Data generated were analysed with STATA 12 and OpenEpi at 0.05 crit

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Panarella, Matthew, and Sharon Hursh. "A retrospective analysis of the tuberculin skin test reactions of a single source population of Mauritian Macaca fascicularis held in quarantine during 2017." PLOS ONE 17, no. 4 (2022): e0265942. http://dx.doi.org/10.1371/journal.pone.0265942.

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A published range of reactions to the tuberculin skin test (TST) using mammalian (human) old tuberculin (MOT) in a population of Mauritius origin Macaca fascicularis in US laboratory animal medicine does not exist. The objectives of this report are to quantify the reactions among juvenile, adolescent, and male adult cynomolgus macaques and to provide the laboratory animal medicine practitioner with a reference range of reactions to MOT in Mauritian juvenile macaques. Monkeys in a US foreign animal quarantine must be tested negative for mycobacterial infection including Mycobacterium tuberculos

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Zavgorodniy, A. I., V. V. Bilushko, S. A. Pozmogova, et al. "Determination of the causes of allergic reactions to tuberculin in cattle." Veterinary Medicine: inter-departmental subject scientific collection, no. 107 (November 8, 2021): 30–36. http://dx.doi.org/10.36016/vm-2021-107-5.

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The article presents the results of cattle examining in four free from tuberculosis livestock farms during 2020–2021. Samples of biological material were collected and studied in the Laboratory for tuberculosis study of the NSC “IECVM”. The causes of allergic reactions to mycobacterial allergens were established by a comprehensive method. The study was aimed to conduct epizootological monitoring and to determine the causes of positive tuberculin skin tests in cattle in four free from tuberculosis farms. These farms were located in different regions of Ukraine. Epizootological, clinical, allerg

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Pavlik, I., F. Bures, P. Janovsky, et al. "The last outbreak of bovine tuberculosis in cattle in the CzechRepublic in 1995 was caused by Mycobacterium bovis subspecies caprae." Veterinární Medicína 47, No. 9 (2012): 251–63. http://dx.doi.org/10.17221/5832-vetmed.

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The last outbreak of bovine tuberculosis in cattle in the CzechRepublic was detected in 1995. Signs of diarrhoea, weight loss and occasional coughing appeared in one 14-year-old cow after giving birth for the thirteenth time. Two months after these symptoms had been observed, it had to be slaughtered and numerous tuberculous lesions were found in its lung tissue, including the pleura. Within three months after the confirmation of the infection and consecutive intra-vitam and post-mortem diagnostics, all 28 remaining head of cattle from the herd (nine cows, seven bulls, six heifers and six calv

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Truzzi, Eleonora, Thais Leite Nascimento, Valentina Iannuccelli, et al. "In Vivo Biodistribution of Respirable Solid Lipid Nanoparticles Surface-Decorated with a Mannose-Based Surfactant: A Promising Tool for Pulmonary Tuberculosis Treatment?" Nanomaterials 10, no. 3 (2020): 568. http://dx.doi.org/10.3390/nano10030568.

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The active targeting to alveolar macrophages (AM) is an attractive strategy to improve the therapeutic efficacy of ‘old’ drugs currently used in clinical practice for the treatment of pulmonary tuberculosis. Previous studies highlighted the ability of respirable solid lipid nanoparticle assemblies (SLNas), loaded with rifampicin (RIF) and functionalized with a novel synthesized mannose-based surfactant (MS), both alone and in a blend with sodium taurocholate, to efficiently target the AM via mannose receptor-mediated mechanism. Here, we present the in vivo biodistribution of these mannosylated

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Mayer, Paul, Katherine Hodge, Dana Kahn, et al. "Interns and Volunteers Crucial in Curating and Digitizing Fossil Invertebrates in the Field Museum’s Fast Growing Mazon Creek Collection." Biodiversity Information Science and Standards 2 (June 13, 2018): e25942. http://dx.doi.org/10.3897/biss.2.25942.

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The Mazon Creek region in Northeastern Illinois is home to a Middle Pennsylvanian (~307 million years old) soft-bodied fossil Lagerstätte of animals and plants that lived along a subtropical swampy coastline. This area was strip mined for coal from 1928 to 1974 and museum geologists and amateur collectors acquired large fossil collections during this time by collecting and splitting millions of nodules unearthed at the mines. These large collections are important because of the rarity of many of the species in the Mazon Creek biota. There are about 250 described fossil invertebrate species fro

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Mayer, Paul, Katherine Hodge, Dana Kahn, et al. "Interns and Volunteers Crucial in Curating and Digitizing Fossil Invertebrates in the Field Museum's Fast Growing Mazon Creek Collection." Biodiversity Information Science and Standards 2 (July 5, 2018): e25942. https://doi.org/10.3897/biss.2.25942.

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The Mazon Creek region in Northeastern Illinois is home to a Middle Pennsylvanian (~307 million years old) soft-bodied fossil Lagerstätte of animals and plants that lived along a subtropical swampy coastline. This area was strip mined for coal from 1928 to 1974 and museum geologists and amateur collectors acquired large fossil collections during this time by collecting and splitting millions of nodules unearthed at the mines. These large collections are important because of the rarity of many of the species in the Mazon Creek biota. There are about 250 described fossil invertebrate species fro

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van Soolingen, Dick, Adri G. M. van der Zanden, Petra E. W. de Haas, et al. "Diagnosis of Mycobacterium microtiInfections among Humans by Using Novel Genetic Markers." Journal of Clinical Microbiology 36, no. 7 (1998): 1840–45. http://dx.doi.org/10.1128/jcm.36.7.1840-1845.1998.

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As a result of DNA typing of Mycobacterium microtiisolates from animals in the United Kingdom and The Netherlands, we diagnosed four human M. microti infections. These are the first M. microti infections among humans to be reported. Three of the patients were immunocompromised and suffered from generalized forms of tuberculosis. The fourth patient was a 34-year-old immunocompetent male with a persistent cough and undefined X-ray abnormalities. Two of the M. microti infections were recognized by their IS6110 restriction fragment length polymorphism (RFLP) patterns, which showed a high degree of

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Jungersen, G., A. Huda, J. J. Hansen, and P. Lind. "Interpretation of the Gamma Interferon Test for Diagnosis of Subclinical Paratuberculosis in Cattle." Clinical and Vaccine Immunology 9, no. 2 (2002): 453–60. http://dx.doi.org/10.1128/cdli.9.2.453-460.2002.

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ABSTRACT A group of 252 cattle without clinical signs of paratuberculosis (paraTB) in 10 herds infected with paraTB and a group of 117 cattle in 5 herds without paraTB were selected. Whole-blood samples were stimulated with bovine, avian, and johnin purified protein derivative (PPD) and examined for gamma interferon (IFN-γ) release. For diagnosis of paraTB, satisfactory estimated specificities (95 to 99%) could be obtained by johnin PPD stimulation irrespective of interpretation relative to bovine PPD or no-antigen stimulation alone, but numbers of test positives in the infected herds varied f

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Kaphle, Krishna. "Veterinary medicine as the core of the one health approach for Nepal's preparedness to pandemics like COVID-19." Applied Science and Technology Annals 1, no. 1 (2020): 122–30. http://dx.doi.org/10.3126/asta.v1i1.30284.

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Coronavirus disease of 2019 (COVID-19) is a declared pandemic of our time and mankind’s advancement in science and medicine till now have been dwarfed and proving insufficient. It looks likely that there is no other option but to live alongside this global, deadly and multifaceted virus and many more emerging and remerging diseases. This opinion piece is a summary from review of literatures and accumulated experience of the author spanning over two decades in teaching, research and clinical setting of veterinary science. The findings stresses on established fact that: Nepal is a hotspot for ma

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Timofeenko, Yu, A. Salomatina, and V. Sinyavskaya. "CATALOG OF THE COLLECTION OF THE «ZOOLOGICAL MUSEUM OF THE SOUTHERN FEDERAL UNIVERSITY. 14. ORDER PASSERIFORMES, FAMILY TURDIDAE." Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry 11, no. 1 (2025): 208–25. https://doi.org/10.29039/2413-1725-2025-11-1-208-225.

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The article continues the series of articles devoted to the description of taxonomic diversity and cataloging of animals represented in the collections of the Museum of the Department of Zoology of the D. I. Ivanovsky Academy of Biology and Biotechnology of the Southern Federal University. D. I. Ivanovsky Academy of Biology and Biotechnology of the Southern Federal University. In recent years, research on the extraction of genetic information from old museum collections has been actively conducted. Zoological collections are an object for study of genetic variability of species, comparative mo

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Pavlik, I., L. Dvorska, M. Bartos, et al. "Molecular epidemiology of bovine tuberculosis in the CzechRepublic and Slovakia in the period 1965–2001 studied by spoligotyping." Veterinární Medicína 47, No. 7 (2012): 181–94. http://dx.doi.org/10.17221/5822-vetmed.

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Spoligotyping was used to examine IS6110-positive DNA of 26 Mycobacterium bovis, M. bovis BCG and M. bovis subsp. caprae non-viable isolates stored up to 10 years. All of these isolates were previously identified by biochemical tests and all 17/17 tested isolates were earlier found virulent for guinea pigs. In total seven spoligotypes, designated S1&ndash;S7, were detected and compared with the spoligotypes of 3 176 isolates in the database of the National Institute of Public Health and the Environment (RIVM) in Bilthoven, the Netherlands. A Neotype M. bovis strain, isolated in 1965 in the

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Sherman, D. M., B. Bray, J. M. Gay, and F. Bates. "Evaluation of the agar gel immunodiffusion test for diagnosis of subclinical paratuberculosis in cattle." American Journal of Veterinary Research 50, no. 4 (1989): 525–30. https://doi.org/10.2460/ajvr.1989.50.04.525.

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SUMMARY Concurrent bacteriologic culture of feces and agar gel immunodifiusion (agid) testing was performed on all cows and bred heifers over 14 months old in 10 dairy herds during a 32-month period to determine the effectiveness of the agid test for the detection of subclinical paratuberculosis. Herds were sampled 5 times and, when possible, culled animals were tested again at slaughter. During 5 herd-wide samplings, Mycobacterium para-tuberculosis was isolated from 139 fecal specimens obtained from 109 cattle. Results of the agid test were simultaneously positive 40 of 139 times (28.8%). Thi

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Thoen, Charles O., Kenneth J. Throlson, Lyle D. Miller, Elmer M. Himes, and Ronald L. Morgan. "Pathogenesis of Mycobacterium bovis infection in American bison." American Journal of Veterinary Research 49, no. 11 (1988): 1861–65. https://doi.org/10.2460/ajvr.1988.49.11.1861.

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SUMMARY Eighteen 12-month-old bison were randomly placed in each of 3 groups (6 animals/group): group-1 bison were exposed to live Mycobacterium bovis, group-2 bison were inoculated with killed M bovis in oil, and group-3 bison were noninfected controls. Six, 6-month-old, tuberculin test-negative calves were placed (pen contact) with group-1 bison 30 days after exposure to M bovis. Tuberculin skin test responses (caudal fold and/or comparative cervical) were detected in all bison in groups 1 and 2 at 2, 4, 6,10, and 12 months. Tuberculin skin test responses were observed in 2 of 6 calves at 9

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Sharma, Arvind, Catherine Schuetze, and Clive J. C. Phillips. "The Management of Cow Shelters (Gaushalas) in India, Including the Attitudes of Shelter Managers to Cow Welfare." Animals 10, no. 2 (2020): 211. http://dx.doi.org/10.3390/ani10020211.

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Gaushala management is a specialized profession requiring particular skills relating to the management of cow shelters or gaushalas, which are traditional and ancient Indian institutions that shelter old, unproductive and abandoned cows, The 1800 registered cow shelters in India have managers who are important stakeholders in the management of cows in these unique institutions. It is important to survey the routine management of these shelters and attitudes of the managers towards cow welfare to identify the constraints and welfare issues. We visited 54 shelters in six states of India for a fa

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Adeoye, Sunday. "Rifampicin-Induced Panic Disorder in a 70-Year-Old Woman With Brucellosis: A Case Report." BJPsych Open 11, S1 (2025): S290. https://doi.org/10.1192/bjo.2025.10701.

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Aims: Panic disorder, also known as paroxysmal episodic anxiety, is a severe, unpredictable, and debilitating form of anxiety that is characterised by sudden onset of palpitations, chest pain, choking sensations, dizziness, and feelings of unreality (depersonalization or derealization). People that suffer from panic attack often have a secondary fear of dying or losing control. Like many other mental illnesses, the causes of panic disorder are unknown, but some predisposing factors have been identified including genetics, neurobiology, medications, psychiatric disorders, psychosocial factors a

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Kiral, Eylem, Ebru kacmaz, Gurkan Bozan, Ozgur Arslanoglu, Omer Kilic, and Ener Cagri Dinleyici. "261. A Rare Case of Meningitis and Symptomatic Hydrocephalus by Listeria Monocytogenes in Dermatomyositis: A Case Report." Open Forum Infectious Diseases 8, Supplement_1 (2021): S237—S238. http://dx.doi.org/10.1093/ofid/ofab466.463.

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Abstract Background Listeria monocytogenes is a gram-positive, facultative anaerobic bacillus common in the intestinal flora of many animals and humans. We describe an unusual case of meningitis by Listeria monocytogenes (LM) complicated by hydrocephalus in a child with dermatomyositis. Methods A 15-year-old girl presented to an outside hospital (OH) after a three-day history of headache, fever and was hospitalized with a diagnosis of meningitis and lumbar puncture performed. CSF sample could not be evaluated clearly due to its hemorrhagic nature. Her past medical history was significant for d

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Skupnevskiy, SV, GM Trukhina, EG Pukhaeva, et al. "On the Mechanism of Development of Autoimmune Diseases Following Exposure to Inactivated Mycobacterium tuberculosis." ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, November 2021, 76–82. http://dx.doi.org/10.35627/2219-5238/2021-29-11-76-82.

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factors, and inadequate hygiene practices contribute to high incidence of tuberculosis in the world. Effective disease prevention shall be based on scientific substantiation of causality and the mechanisms of its development. Objective: The study aimed to investigate the etiopathogenesis of autoimmune disorders associated with the exposure of warm-blooded animals to heat killed M. tuberculosis. Materials and methods: We determined hematological parameters of old Wistar rats using standard methods and estimated the activity of lactate and succinate dehydrogenases (LDH, SDH) in lymphocytes (mito

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Moorthy, Swathy, Emmanuel Bhaskar, Shivakumar S, and Santhi Silambanan. "Tuberculosis Diagnostics, a journey from the past Experiences to the Future Directions, Review." Arab Gulf Journal of Scientific Research, April 17, 2022, 82–99. http://dx.doi.org/10.51758/agjsr-02-2021-0012.

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Purpose: Tuberculosis caused by Mycobacterium tuberculosis is believed to have been acquired from animals especially cattle. Not one country across the globe is spared of the disease. The infection gets established through respiratory system where they are either latent or active. Depending upon the immune status or coexisting infection or other health disorders the infection may be either contained within the lungs or spread to other parts of the body. Hence rapid and accurate diagnosis is needed to initiate appropriate treatment. Sputum studies are being followed for diagnosis of tuberculosi

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Narnaware, Shirish Dadarao, Basanti Jyotsana, Rakesh Ranjan, Ved Prakash, Shyam Sundar Choudhary, and Artabandhu Sahoo. "Case Report: Congenital tuberculosis in an aborted dromedary camel fetus." Frontiers in Veterinary Science 9 (July 28, 2022). http://dx.doi.org/10.3389/fvets.2022.956368.

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Tuberculosis (TB) is a serious public health problem worldwide, especially in tropical developing countries. Nevertheless, reports on congenital TB in humans and animals are extremely rare. In this study, abortion was reported in an 8-year-old she-camel at the 9th month of gestation. The she-camel appeared healthy in clinical examination, had a good body condition score, normal appetite, and had no signs of respiratory disease and fever. The expelled placenta was dark red-colored, thickened, and edematous with multifocal to coalescing ecchymotic hemorrhages on the allantoic surface. The striki

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Shi, Jichan, Wenjie Wu, Kang Wu, et al. "The diagnosis of leptospirosis complicated by pulmonary tuberculosis complemented by metagenomic next-generation sequencing: A case report." Frontiers in Cellular and Infection Microbiology 12 (October 4, 2022). http://dx.doi.org/10.3389/fcimb.2022.922996.

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Leptospirosis is a zoonotic infection caused by the pathogenic Leptospira. Leptospirosis is transmitted mainly through contact with contaminated rivers, lakes, or animals carrying Leptospira. Human leptospirosis has a wide range of non-specific clinical manifestations ranging from fever, hypotension, and myalgia to multi-organ dysfunction, which severely hampers the timely clinical diagnosis and treatment of leptospirosis. Therefore, there is an urgent clinical need for an efficient strategy/method that can be used for the accurate diagnosis of leptospirosis, especially in critically ill patie

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Tian, Xirong, Yamin Gao, Chunyu Li, et al. "A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis." Frontiers in Pharmacology 15 (January 3, 2025). https://doi.org/10.3389/fphar.2024.1400436.

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The efficacy of many compounds against Mycobacterium tuberculosis is often limited when administered via conventional oral or injection routes due to suboptimal pharmacokinetic characteristics. Inhalation-based delivery methods have been investigated to achieve high local therapeutic doses in the lungs. However, previous models, typically employing wild-type M. tuberculosis strains, were intricate, time-consuming, labor-intensive, and with poor reproducibility. In this study, we developed an autoluminescence-based inhalation administration model to evaluate drug activity by quantifying relativ

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Winter, John M., Jennifer N. Langan, Jennifer A. Landolfi, Tyler Thacker, and Katie W. Delk. "Disseminated nontuberculous mycobacteriosis due to Mycobacterium avium subsp. hominissuis infection in a reindeer from a zoo." Journal of Veterinary Diagnostic Investigation, January 28, 2025. https://doi.org/10.1177/10406387241307644.

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Bacteria in the Mycobacterium tuberculosis complex and nontuberculous mycobacteria may affect a variety of animal species under human care and pose public health risks as zoonotic pathogens. A case of sudden onset of lethargy and increased respiratory effort in a 5-y-old, intact female reindeer ( Rangifer tarandus) under managed care had progressed to severe dyspnea despite aggressive treatment. The animal was euthanized due to poor prognosis. Postmortem findings included: disseminated miliary nodules in the lungs, pleura, small intestine, liver, and spleen; enlarged mesenteric lymph nodes; di

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Radi, Radi, and Dwiyan Maharani Mutiara Firdaus. "Literature Review : Determinant of Latent Tuberculosis Infection (LTBI) in Developing Country." Insights in Public Health Journal 5, no. 1 (2024). http://dx.doi.org/10.20884/1.iphj.2024.5.1.12214.

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Background: The problem of TB in Indonesia is increasingly worrying considering that Indonesia is the second country with the most TB cases in the world. Serious efforts are needed to break the chain of TB transmission as early as possible by focusing on preventing risk factors for transmission. TB transmission often occurs within the family, the vulnerable group being infected with TB who live in the same house as TB sufferers. The study aims to know the determinants of latent TB infection in children under 15 years old and adults in developing countries. Method: This study used the literatur

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Giannitti, Federico, Matías A. Dorsch, Sofía Fernández-Ciganda, et al. "Canine leproid granuloma caused by a member of the Mycobacterium tuberculosis complex." Journal of Veterinary Diagnostic Investigation, May 19, 2023, 104063872311768. http://dx.doi.org/10.1177/10406387231176816.

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Canine leproid granuloma (CLG) is a chronic form of dermatitis that has been associated with nontuberculous mycobacterial infections in Africa, Oceania, the Americas, and Europe. We report here a case of CLG associated with a member of the Mycobacterium tuberculosis complex (MTBC), which could be of public health concern. An 8-y-old pet dog developed 0.5–1-cm diameter, raised, firm, nonpruritic, alopecic, painless skin nodules on the external aspects of both pinnae. Histologic examination revealed severe pyogranulomatous dermatitis with intracellular Ziehl-Neelsen–positive bacilli that were im

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Adimasie, Balemual, and sisay Atalel. "Evaluation of the Awareness of Bovine Tuberculosis, Brucellosis and its Associated Factors in Lay Gayint District, Ethiopia." Journal of Public Health and Community Medicine, 2024, 1. http://dx.doi.org/10.5455/jphcm.20240602121725.

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Background and Aim: Zoonosis are the current global public health challenges. Animal-origin food-borne zoonosis are transmitted from animals to humans and vice versa. It accounts for 75% of all emerging and 60% of all infectious diseases. It is highly associated with the consumption of raw milk and meat and direct or indirect contact with animals. Materials and Methods: A community-based cross-sectional study was conducted to assess awareness of Bovine tuberculosis, brucellosis, and its associated factors in Lay Gayint District, South Gondar Zone, Ethiopia. Among 628 proportionally allocated a

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Alam, Md Shah, Ping Guan, Yuting Zhu, et al. "Comparative genome analysis reveals high-level drug resistance markers in a clinical isolate of Mycobacterium fortuitum subsp. fortuitum MF GZ001." Frontiers in Cellular and Infection Microbiology 12 (January 4, 2023). http://dx.doi.org/10.3389/fcimb.2022.1056007.

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IntroductionInfections caused by non-tuberculosis mycobacteria are significantly worsening across the globe. M. fortuitum complex is a rapidly growing pathogenic species that is of clinical relevance to both humans and animals. This pathogen has the potential to create adverse effects on human healthcare.MethodsThe MF GZ001 clinical strain was collected from the sputum of a 45-year-old male patient with a pulmonary infection. The morphological studies, comparative genomic analysis, and drug resistance profiles along with variants detection were performed in this study. In addition, comparative

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Carlos Gaspar, Juan, Tyler Moeller, Jessica Buchta, et al. "269. Reference Data of Biochemical and Hematology Parameters in Juvenile and Adult Owl Monkeys (Aotus nancymaae) for Biomedical Research." Open Forum Infectious Diseases 10, Supplement_2 (2023). http://dx.doi.org/10.1093/ofid/ofad500.341.

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Abstract Background Non-human primates (NHP), including New World monkeys (NWM), are used in varied fields of biomedical research encompassing infectious disease, behavioral sciences and drug and vaccine development. In these studies, normal reference values for biochemical and hematological parameters are often needed for comparison with experimental results. These blood parameters are useful guides in reaching a diagnosis, estimating the prognosis of the disease and monitoring the progress of treatment. Although there are various reports of biochemical and hematologic parameters in Old World

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Lal, Rattan. "Zoonotic Diseases as A Historical Public Health Problem in District Poonch and Its Adjoining Area, Union Territory of Jammu and Kashmir, India." International Journal of pharma and Bio Sciences 13, no. 3 (2022). http://dx.doi.org/10.22376/ijpbs.2022.13.3.b1-11.

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The main aim of this study in far flung border area of Poonch on the actual line control of pak- occupied Kashmir is to know the frequent out breaks of diseases, more incidences of Zoonotic diseases, emerging and re-emerging of zoonotic infections in district Poonch and its adjoining areas within objective to understand the magnitude of gravity of major emerging and remerging zoonotic public health problem not only in India but also in different parts of world. This study also deals with various aspects of prevalence of zoonotic diseases in District Poonch and its adjoining areas to provide a

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Isaguliants, Maria, and Felicity Jane Burt. "Perspective Technologies of Vaccination: Do We Still Need Old Vaccines?" June 2, 2022. https://doi.org/10.3390/vaccines10060891.

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Until December 2019, we were living in the world of successfully functioning vaccines and vaccination programs. Smallpox was eradicated, polio close to being eradicated, HBV infection controlled in endemic regions, flu counteracted by seasonal vaccinations, previously deadly bacterial infections almost forgotten; respective diseases often not recognized by the medical doctors when occasional cases occurred [1]. A breakthrough finally came for malaria, promising an effective vaccine in a relatively near future [2]. Absence of success with the HCV vaccine was almost forgotten due to the success

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Chies, Agnaldo B., Isabela F. S. Nascimento, Maria Angélica Spadella, et al. "Arthritis induces Inflammatory Cell Infiltration, Oxidative Stress and Browning in Rat Perivascular Adipose Tissue." Physiology 40, S1 (2025). https://doi.org/10.1152/physiol.2025.40.s1.0717.

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In rats submitted to adjuvant-induced arthritis (AIA), joint-derived cytokines cause sarcopenia and fat mass loss. This mass reduction was also observed in the perivascular adipose tissue (PVAT), where the inflammatory actions of arthritis are much less understood. In this context, we hypothesize that AIA causes inflammation in PVAT with its own characteristics, with temporal evolution followed by remission once the model is self-limiting. Thus, the present study aimed to characterize the temporal course of the inflammatory process caused by AIA in PVAT to identify its peak, which is the ideal

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Swain, Satish, Sudesh Gourav, Taruna Pahuja, Gagandeep Singh, Immaculata Xess, and Prayas Sethi. "P486 Disseminated Cryptococcosis diagnosed on fine needle aspiration cytology." Medical Mycology 60, Supplement_1 (2022). http://dx.doi.org/10.1093/mmy/myac072.p486.

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Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Objectives (Case): A 48-year-old male with no prior comorbidities presented to our infectious disease clinic with intermittent low-grade fever and gradual progressive swelling in his left axilla for 3 months. On further probing, the patient also gives a history of weight loss of around 7 kg. The patient belonged to a northern state of the Indian subcontinent and owned a grocery shop, where he worked. There was no recent or remote travel history, no history of exposure to animals or birds, no high-risk behavior, and no past or kn

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Souza, Cristiane Trevisan Viana de, Daniela Souza Prass, Roberto Lopes Souza, et al. "Granulomatous Lymphadenitis in a Dog Caused by Mycobacterium intracellulare." Acta Scientiae Veterinariae 50 (February 3, 2022). http://dx.doi.org/10.22456/1679-9216.118107.

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Background: Mycobacteriosis is caused by bacteria belonging to the genus Mycobacterium, with considerable zoonotic potential and risk to public health. Infection in dogs is rare and is usually associated with immunosuppression, resulting from eating meat or contact with contaminated soil or fomites. Dogs are also known as potential sources for the spread of atypical tuberculosis in humans and other animals. This paper aims to describe the clinical, cytological, histopathological, and molecular findings of a male canine seen at University Veterinary Hospital of Cuiabá, Mato Grosso, with general

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sprotocols. "Cutaneous Two-Stage Chemical Carcinogenesis." December 30, 2014. https://doi.org/10.5281/zenodo.13614.

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Authors: Renata B. Filler, Scott J. Roberts and Michael Girardi Corresponding author ([michael.girardi@yale.edu](michael.girardi@yale.edu)) ### INTRODUCTION The induction of cutaneous carcinogenesis in mice by topical administration of chemicals enables the local, systemic, and environmental factors that influence tumor susceptibility, growth, and progression to be studied in the laboratory. Chemical carcinogenesis in mouse skin has been used for several decades, and continues to help in the identification of important molecular and immunological pathways involved in cutaneous malignancy. This

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