Dissertations / Theses: 'Tulsa'

1

McLean, Brad H. "Enhancing expository preaching at Berean Baptist Church, Tulsa, Oklahoma." Theological Research Exchange Network (TREN), 2006. http://www.tren.com/search.cfm?p053-0308.

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2

Smith, Greta Katherine. ""The Battling Ground": Memory, Violence, and Resistance in Greenwood, North Tulsa, Oklahoma, 1907-1980." PDXScholar, 2018. https://pdxscholar.library.pdx.edu/open_access_etds/4559.

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Tulsa, Oklahoma's historically African American neighborhood of Greenwood in North Tulsa has long been contested terrain. Built by black settlers beginning in the late nineteenth-century, the neighborhood evolved into a vibrant community challenged by waves of violence--segregation at statehood in 1907, the Tulsa Race Riot of 1921, ongoing disinvestment, and processes of urban renewal beginning in the late 1950s--that contributed to the erosion of the neighborhood and the eventual displacement of many area residents into remote housing projects further into North Tulsa. These waves of violence were propelled by Oklahoma lawmakers, local Tulsa government officials, members of the Ku Klux Klan, and private white citizens who worked to expand the city's color line by controlling the placement and visibility of black people in Tulsa and gain ownership of Greenwood--as the neighborhood was, and is, located on desirable land. The people of Greenwood met these waves of violence with acts of resistance. They organized and lobbied against segregation at statehood, fought to save their community during the Tulsa Race Riot, and galvanized to rebuild almost immediately after. They maintained a culture of interdependence that contributed to strength in community and economy. Beginning in the late 1950s, they protested their displacement. However, by the late 1980s, the ravages of slum clearance and expressway building had rendered much of Greenwood unlivable and many residents had no choice but to relocate. The loss of historic place and increased distance between community members made it difficult to maintain their shared identity and culture of interdependence. Taken altogether, these four waves of violence functioned as tools to carry out the city of Tulsa's longstanding agenda of reclaiming the prime urban real estate of Greenwood while broadening the area of land that segregated black & white Tulsa. At the root existed white supremacy: the belief in the inherent superiority of the white race and its fundamental right to dominate society.

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3

Fan, Sheng. "An evaluation of the science enrichment program in Tulsa Public Schools /." Access abstract and link to full text, 1991. http://0-wwwlib.umi.com.library.utulsa.edu/dissertations/fullcit/9203793.

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4

Letcher, Charles. "Green computing - Desktop computer power management at the city of Tulsa." Thesis, Oklahoma State University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=1542205.

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One type of Green Computing focuses on reducing power consumption of computers. Specialized software like 1E/Nightwatchman aids in reducing the power consumption of desktop computers by placing them in a low power state when not in use. This thesis describes the implementation of 1E/Nightwatchman power management software on two thousand desktop computers at the City of Tulsa. It shows the method used to predict power savings of $100,000.00 per year and compares the prediction to the actual savings after one year of operation.

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5

Kugler, Karen E. "Guilt conceptualization and measurement /." Access abstract and link to full text, 1989. http://0-wwwlib.umi.com.library.utulsa.edu/dissertations/fullcit/9010199.

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6

Conner, John H. "A self guided church consultation for Memorial Bible Church of Tulsa, Oklahoma." Online full text .pdf document, available to Fuller patrons only, 2004. http://www.tren.com.

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7

Baxter, Nathan. "A case study of the volunteer culture of Liberty Church in Tulsa, Oklahoma." Theological Research Exchange Network (TREN) Access this title online, 2005. http://www.tren.com.

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8

Lee, Hee Min. "Collective action for community-based hazard mitigation: a case study of Tulsa project impact." Diss., Texas A&M University, 2004. http://hdl.handle.net/1969.1/2806.

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During the past two decades, community-based hazard mitigation (CBHM) has been newly proposed and implemented as an alternative conceptual model for emergency management to deal with disasters comprehensively in order to curtail skyrocketing disaster losses. Local community members have been growingly required to share information and responsibilities for reducing community vulnerabilities to natural and technological hazards and building a safer community. Consequently they are encouraged to join local mitigation programs and volunteer for collective mitigation action, but their contributions vary. This research examined factors associated with Tulsa Project Impact partners?? contributions to collective mitigation action. In the literature review, self-interest and social norms were identified and briefly discussed as two determinants to guide partners?? behavior by reviewing game theoretic frameworks and individual decision-making models. Partners?? collective interest in building a safer community and feelings of obligation to participate in collective mitigation action were also considered for this study. Thus, the major factors considered are: (1) collective interests, (2) selective benefits, (3) participation costs, (4) norms of cooperation, and (5) internalized norms of participation. Research findings showed that selective benefits and internalized norms of participation were the two best predictors for partners?? contributions to collective mitigation action. However, collective interests, participation costs, and norms of cooperation did not significantly influence partners?? contributions.

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9

Stick, Michael R. "Equipping the laity of Winnetka Heights Baptist Church, Tulsa, Oklahoma, to practice personal evangelism." Online full text .pdf document, available to Fuller patrons only, 2001. http://www.tren.com.

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10

Webb, Holbrook Lawson. "Self-Directed Learning Projects by Older Learners: Roles for Educational Organizations in Initiating and Facilitating the Process." Thesis, University of North Texas, 1996. https://digital.library.unt.edu/ark:/67531/metadc278602/.

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Ways in which educational structures can initiate and facilitate older learners' self-directed learning projects are described in this study. The research was guided by questions related to the ways that educational organizations can facilitate the learning process for older learners. This study involved two distinct phases of research. In the first phase, a survey was administered to approximately 100 older learners at four organizations for senior citizens; the four organizations were Hillcrest Center for 55+, Golden Learning Opportunities and Workshop, Tulsa Senior Services, and Retired Senior Volunteer Program. The survey enabled the researcher to identify the 10 most frequented sites for gathering information related to the learning projects of senior citizens in Tulsa, Oklahoma. The survey respondents were volunteer participants from classes, social occasions, and other learning opportunities offered by the organizations. The survey produced three sites where older learners pursued learning activities. Phase two involved ethnographic techniques in order to identify and describe at each three sites specific educational structures that facilitated older learners' self-directed learning projects. The descriptions from each of the identified sites involved three data-collection techniques. The data-collection techniques used included interviews, observation, and artifact collection. The focus of this phase was to describe the educational structures that facilitated the development of learning projects endemic to each site as identified by the older learners. Notes taken during interviews and observations were transcribed, coded, and analyzed. Interviews were also transcribed. The transcripts were transferred to a conceptually clustered matrix for each site. Analyses of the administrator interviews, participant interviews, educational opportunity observations, and artifact collection at each site revealed patterns and trends that represent the educational structures that appeal to older learners as they pursue learning projects. The findings indicate that four patterns or trends were common to each site. These four patterns included accessible materials, service-minded staff, entertainment, and teacher-directed learning style.

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11

Khup, Nang Khen. "Evaluating the impact of family devotions upon selected families from Zomi Christian Community of Tulsa /." Free full text is available to ORU patrons only; click to view, 2007. http://proquest.umi.com/pqdweb?did=1703634501&sid=3&Fmt=2&clientId=456&RQT=309&VName=PQD.

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12

Davis, Gregory L. "Increasing appreciation for multigenerational communion in a suburban congregation /." Free full text is available to ORU patrons only; click to view:, 2006. http://proquest.umi.com/pqdweb?did=1296086861&sid=1&Fmt=2&clientId=456&RQT=309&VName=PQD.

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13

Yoo, Yongwung. "The experience of the Holy Spirit on members' faith in the Tulsa Korean Presbyterian Church /." Free full text is available to ORU patrons only; click to view:, 2005. http://proquest.umi.com/pqdweb?did=1072514251&sid=1&Fmt=2&clientId=456&RQT=309&VName=PQD.

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14

Norwood, Woodrow E. "The Tulsa Association of Elementary School Principals, 1944-1985 dealing with changing superintendents and changing times /." Access abstract and link to full text, 1986. http://0-wwwlib.umi.com.library.utulsa.edu/dissertations/fullcit/8707517.

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15

Seo, Jeongkwan. "Personal spiritual impact of the Korean churches' early morning prayer model at Woodlake Assembly of God /." Free full text is available to ORU patrons only; click to view:, 2004. http://wwwlib.umi.com/cr/oru/fullcit?p3150447.

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16

Corrington, Mary. "Understanding gender differences in the effects of the Tulsa pre-K program on children's school readiness." CONNECT TO ELECTRONIC THESIS, 2008. http://dspace.wrlc.org/handle/1961/4556.

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17

Lovett, Phyllis F. "Principals' perspectives on transitioning from a traditional calendar to a year-round calendar in the Tulsa metropolitan area /." Free full text is available to ORU patrons only; click to view:, 2006. http://proquest.umi.com/pqdweb?did=1147184681&sid=7&Fmt=2&clientId=456&RQT=309&VName=PQD.

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18

Khaung, John Dai. "Increasing knowledge of praise and worship in a nondenominational immigrant congregation /." Free full text is available to ORU patrons only; click to view, 2007. http://proquest.umi.com/pqdweb?did=1706818061&sid=2&Fmt=2&clientId=456&RQT=309&VName=PQD.

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19

Rossman, Edwin J. (Edwin John). "Individual Resources, Social Environment, and Flood Victimization." Thesis, University of North Texas, 1990. https://digital.library.unt.edu/ark:/67531/metadc330855/.

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The study is a contextual analysis of flood victimization. Victimization is defined as the social, psychological, and physiological aftermath experienced by victims of a disaster. Disaster researchers concentrate on the victims' characteristics to explain the varying degrees of their victimization, providing only ambiguous results. Theorists such as Kreps, Wildavsky, and Douglas contend that the outcomes of disasters are contingent upon social structure. This analysis treats victimization as one such outcome. The condition and behavior of individuals can be explained by the presence of disaster and the conditions of social organization. A model explains victimization based on individual's attributes (individual resources), his social environment, and the disaster characteristics. This study uses the 1984 Mingo Creek Flood Victims Survey data to test the model. The data contain information measuring victimization. The survey data are linked with 1980 Census tract data. The tract data provide indicators of the social networks. This tract information, the contextual variables, taps the social conditions, including poverty, unemployment, geographic mobility, and family patterns. This study uses factor analysis to identify the dimensions of victimization. Regression tests the relationship between the contextual variables, the individual resource variables, the disaster characteristic variables, and victimization. The results of the analysis show that victimization is multidimensional with different types of variables being significant predictors for each dimension of victimization, one variable indicating the intensity of the disaster, the dollar value of damage victims experienced, is found to be a significant predictor of the psychological, physiological, and social disruption aspects of victimization. Variables measuring the family and unemployment patterns in the victims' census tract are significant predictors of the psychological and social disruption aspect of victimization. The findings provide general support for the proposed model of victimization. However, victimization is multidimensional with each dimension having a unique set of predictors. Based on the findings, this study suggests that future research focus on measurement and conceptualization of the characteristics of disasters and the victims' social environment.

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20

Richardson, Mark L. "Equipping Glenwood Baptist Church for revitalization through a study of Paul's message of the cross to the Corinthians." Theological Research Exchange Network (TREN), 2007. http://www.tren.com/search.cfm?p054-0264.

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21

Haokip, Khaigin. "Increasing parents' knowledge about the needs for spiritual training of children of immigrant families in the Myanmar Christian Church /." Free full text is available to ORU patrons only; click to view, 2007. http://proquest.umi.com/pqdweb?did=1994545921&sid=1&Fmt=2&clientId=456&RQT=309&VName=PQD.

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22

Scales, Jimmy V. "The Relationships among the number of student transfers and the type of transfer on academic achievement, attendance and suspensions in Tulsa Public Schools' middle schools, 1987-1991 /." Access abstract and link to full text, 1991. http://0-wwwlib.umi.com.library.utulsa.edu/dissertations/fullcit/9213730.

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23

Reed, Jeffrey J. "The design and implementation of a congregational-care ministry for Kirk of the Hills Presbyterian." Online full text .pdf document, available to Fuller patrons only, 2004. http://www.tren.com.

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24

Ehinger, June Marek. "The validation of selected assessment center activities for incumbent school administrators who participated in the University of Tulsa Education Management Development Program /." Access abstract and link to full text, 1986. http://0-wwwlib.umi.com.library.utulsa.edu/dissertations/fullcit/8612431.

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25

Brady, Paul. "Equipping young adult members at Ranch Acres Baptist Church, Tulsa, Oklahoma to use principles of fellowship as a strategy for evangelistic church growth." Online full text .pdf document, available to Fuller patrons only, 1999. http://www.tren.com.

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26

Barnett, John Samuel. "A research project using the long-term sermon preparation model for preaching the Book of the Revelation to stimulate spiritual development at Tulsa Bible Church." Theological Research Exchange Network (TREN), 1999. http://www.tren.com.

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27

Harder, Kenneth J. "Clerical sexual abuse of minors an analysis of the policy of the diocese of Tulsa in comparison with the USCCB essential norms and Sacramentorum sanctitatis tutela /." Online full text .pdf document, available to Fuller patrons only, 2003. http://www.tren.com.

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28

Ihim, Anthony Chukwuma. "A biblical teaching series to create a change in attitude toward God's ability to meet the needs of Nigerian immigrants /." Free full text is available to ORU patrons only; click to view:, 2006. http://proquest.umi.com/pqdweb?did=1328047191&sid=1&Fmt=2&clientId=456&RQT=309&VName=PQD.

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29

Kuhns, Alice Pauline. "A study of the relationship between a participatory management model and selected variables." Diss., Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/49814.

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30

Niemelä, T. (Tiia). "Tulvien aiheuttamat seuraukset ja niihin vaikuttavat tekijät:tapausesimerkkeinä Kiinan tulva, Pohjanmeren tulva ja Porin kaupunkitulva." Bachelor's thesis, University of Oulu, 2019. http://jultika.oulu.fi/Record/nbnfioulu-201901181074.

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Tiivistelmä. Tässä tutkimuksessa perehdytään aikaisemman kirjallisuuden pohjalta tulvien seurauksiin ja niihin vaikuttaviin tekijöihin. Lisäksi eri tulvatyyppejä kuvastavien esimerkkitapauksien kautta perehdyn tarkemmin eri tulvatyyppien seurauksiin. Vesistötulvaa edustaa vuonna 1931 tapahtunut tulva Kiinassa, meritulvaa vuonna 1953 tapahtunut Pohjanmeren tulva ja hulevesitulvaa Porissa vuonna 2007 sattunut kaupunkitulva. Tulva on vallitsevista luonnonoloista johtuva luonnonilmiö. Tulvat voidaan jakaa kolmeen eri kategoriaan; vesistötulviin, meritulviin ja hulevesitulviin. Vesistötulvat syntyvät vesistöjen, eli jokien ja järvien, vedenpinnan noustessa, meritulvat syntyvät merenpinnan noustessa normaalin vaihtelun yläpuolelle ja hulevesitulvat puolestaan syntyvät, kun hulevesirakenteiden, kuten viemäriverkostojen ja avo-ojien, kapasiteetti ylittyy runsaan sateen seurauksena. Tulvat voivat aiheuttaa vahingollisia seurauksia esimerkiksi ihmisten terveydelle ja turvallisuudelle, ympäristölle, infrastruktuurille, taloudelliselle toiminnalle ja kulttuuriperinnölle. Seuraukset voidaan luokitella suoriin, epäsuoriin, aineellisiin ja aineettomiin seurauksiin. Suorat seuraukset syntyvät välittömästä kosketuksesta tulvaveden kanssa. Epäsuorat seuraukset puolestaan ovat pidemmän aikavälin seurauksia, jotka ovat välillisesti yhteydessä itse tulvaan. Aineellisille seurauksille voidaan laskea rahallinen arvo, kun taas aineettomia seurauksia puolestaan ei voida mitata rahassa. Tulvat tuhoavat rakennuksia, omaisuutta, satoja ja karjaa. Ne usein aiheuttavat katkoksia infrastruktuurissa ja pilaavat maaperää. Tulvilla on myös merkittävä vaikutus ihmisiin kuolemantapausten, loukkaantumisien ja jälkikäteen ilmenevien psyykkisten häiriöiden kautta. Tulvan seurauksiin vaikuttaa tulvan luonteenomaiset piirteet, alueen ominaispiirteet ja väestön sosiaaliset ominaisuudet. Esimerkiksi ajankohta, kesto, syvyys, topografia, vallitseva ilmasto, urbanisaation taso sekä väestön ikä ja rakenne. Yksi merkittävimmistä vaikuttavista tekijöistä on yhteiskunnan varautuminen ja valmius.

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31

Frazier, Steven L. "Bridging the gap deepening worshippers' [sic] understanding of the Lord's Supper through doctrinal preaching /." Theological Research Exchange Network (TREN), 2007. http://www.tren.com/search.cfm?p075-0071.

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32

Osigian, Barkef K. "Program evaluation of the course "Discipleship for leadership" at Coppell Bible Fellowship." Theological Research Exchange Network (TREN) Access this title online, 2006. http://www.tren.com.

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33

Holmberg, P. T. (Paul-Thor). "Mennä ja tulla -verbit ja asiaintilan ikkunointi." Master's thesis, University of Oulu, 2017. http://urn.fi/URN:NBN:fi:oulu-201701121060.

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Tarkastelen pro gradu -tutkielmassani sitä, millä tavoin mennä ja tulla -verbien ilmaiseman muuttujan reitti ikkunoidaan suomen kielessä. Muuttuja reitin voi käsitteistää ikään kuin liikepolkuna, joka sisältää sekä alku-, keski- että loppuosan riippuen siitä, mitä osia polusta nostetaan huomion ikkunaan. Huomion ikkunointi on kielitieteilijä Leonard Talmyn kehittämä teoria, ja hän on käyttänyt seuraavaa esimerkkilausetta liikepolun havainnollistamiseen: laatikko, joka oli lentokoneen lastiruumassa, putosi koneesta ilman halki mereen. Lauseessa muuttujana toimii putoava laatikko, ja tämän alkupisteeksi määrittyy erosijainen paikan adverbiaali koneesta. Itse ilmalento määrittyy puolestaan polun keskikohdaksi (ilman halki), ja päätepisteeksi kuvatussa tapahtumassa hahmottuu meri, johon laatikko lopulta putoaa. Liikepolun kaikkien osien nostaminen huomion ikkunaan on kuitenkin harvinaista, koska pyrimme yleensä valikoimaan tuottamaamme informaatioon vain itsemme mielestä kaikista olennaisimman osan. Jos edellisestä esimerkkilauseesta nostettaisiin huomion ikkunaan ainoastaan sen loppuosa, esiintyisi se siis muodossa laatikko, joka oli lentokoneen lastiruumassa, putosi mereen. Tutkimukseni perusteella pelkästään polun loppuosan nostaminen huomion ikkunaan onkin kaikista yleisin tapa esittää liikepolku; kaikkiaan 400 esimerkkilauseesta tai -virkkeestä koostuvasta aineistostani 237 tapausta edusti kyseistä ikkunointityyppiä. Maksimaalista, kaikki liikepolun osat huomion ikkunaan nostavaa ikkunointityyppiä edusti aineistossani ainoastaan 14 lausetta tai virkettä. Loput tapaukset edustivat muita mahdollisia ikkunointitapoja. Liikepolun alku-, keski- ja loppuosat voivat esiintyä lauseessa yhteensä seitsemällä eri tavalla riippuen siitä, mitä osia siihen sisällyttää ja mitä siitä jättää pois. Tilastoinnin lisäksi olen kiinnittänyt huomiota siihen, millaisia keinoja huomion ikkunoimiseen käytetään ja sitä, millä tavoin konkreettinen ja abstraktinen liike eroavat toisistaan huomion ikkunoinnin osalta. Olen myös tehnyt havainnon, jonka mukaan huomion ikkunoinnin tarkastelua ei ole tarpeellista rajoittaa pelkästään lauseen mittaisiin kokonaisuuksiin, vaan virkkeen eri verbien omat argumentit voivat yhdessä muodostaa liikepolun. Kutsun tätä ilmiötä polun kerrostuneisuudeksi. Olen kerännyt aineistoni CSC:n kielipankin Korp-työkalun avulla. Korpin avulla on mahdollista tehdä konkordanssihakuja kieliopillisesti jäsennetyistä tekstikorpuksista. Sen kautta pääsee myös käyttämään kirjoitetun ja puhutun nykysuomen sekä varhaisnykysuomen ja vanhan kirjasuomen aineistoja. Oma aineistoni on peräisin pääasiassa Kansalliskirjaston suomenkielisten lehtien kokoelmista sekä Europal-korpuksesta, joka sisältää Euroopan parlamentissa käytyjen keskustelujen käännöstekstejä. Aineistoni lauseista ja virkkeistä puolet ovat mennä-verbillisiä ja puolet tulla-verbillisiä.

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34

Klempa, Boris. "Dobrava and Tula hantaviruses from Central Europe." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2005. http://dx.doi.org/10.18452/15204.

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Hantaviren (Familie Bunyaviridae) sind Erreger, die von Nagetieren auf den Menschen übertragen werden und Hämorrhagische Fieber mit Renalem Syndrom (HFRS) auslösen. Die vorgelegte Arbeit beinhaltet derartige Ergebnisse zu zwei europäischen Hantaviren, dem Dobravavirus (DOBV) und dem Tulavirus (TULV). DOBV ist ein wichtiger HFRS-Erreger in Europa. DOBV Stämme kommen in mindestens zwei Nagerspecies, der Gelbhalsmaus (Apodemus flavicollis) und der Brandmaus (A. agrarius) vor. In Übereinstimmung mit diesen natürlichen Wirten bilden die Virusstämme zwei genetische Linien: DOBV-Af und DOBV-Aa. Die phylogenetischen Analysen von den Nukleotidsequenzen der S-, M- und L-Segmente von sympatrisch vorkommenden DOBV-Af und DOBV-Aa Stämmen aus Mitteleuropa zeigten das Vorkommen von Reassortmentprozessen der Genomsegmente während der Evolution der Virusspecies. Ausserdem, wurde die virale Nukleotidsequenz aus einem DOBV-seropositiven HFRS-Patienten aus Detschland amplifiziert. Damit wurde erstmalig der molekulare Beweis erbracht, dass DOBV in Mitteleuropa HFRS auslöst und dass die DOBV-Aa Linie humanpathogen ist. Aus einer in der Slowakei gefangenen A. agrarius Maus haben wir ein neues Virusisolat gewonnen, welches "Slovakia (SK/Aa)" genannt wurde. SK/Aa ist das bisher einzige Virusisolat, das die DOBV-Aa Linie repräsentiert. Es wurde gemeinsam mit einem Isolat der DOBV-Af Linie zur vergleichenden Typisierung der Antikörper von mitteleuropäischen HFRS-Patienten mittels Fokusreduktionsneutralisationstest eingesetzt. Die Seren der meisten Patienten zeigten die höchsten neutralisierenden Antikörpertiter gegenüber SK/Aa, was die Schlussfolgerung zulässt, dass DOBV-Aa Stämme für die meisten DOBV-Infektionen in Mitteleuropa verantwortlich sind. TULV wird durch die Feldmaus (Microtus arvalis) beherbergt. Die Fähigkeit zur Auslösung von HFRS war bisher wenig bekannt. Wir haben den ersten Fall von HFRS gefunden, der mit einer TULV Infektion assoziiert ist. Aus demselben geographischen Gebiet in Nordostdeutschland konnten aus Feldmäusen TULV Nukleotidsequenzen amplifiziert werden. In phylogenetischen Analysen clustern sie mit Stämmen aus Polen und bilden mit diesen gemeinsam eine eigene, neue genetische Linie. Ausser dem hier untersuchten DOBV und dem länger bekannten Puumalavirus ist TULV offenbar das dritte Hantavirus, das in Mitteleuropa HFRS hervorruft.
Hantaviruses (Bunyaviridae family) are rodent-borne bunyaviruses that cause hemorrhagic fever with renal syndrome (HFRS) in Eurasia. This thesis presents novel data about two European hantaviruses, Dobrava virus (DOBV) and Tula virus (TULV). DOBV is an important etiologic agent of HFRS in Europe. DOBV strains were found to be hosted by at least two different rodent species, yellow-necked mouse (Apodemus flavicollis) and striped field mouse (A. agrarius). According to their natural hosts they form the distinct genetic lineages DOBV-Af and DOBV-Aa, respectively. We have determined and analysed the complete S and M, and partial L segment nucleotide sequences of sympatrically occurring DOBV-Af and DOBV-Aa strains from Central Europe. Molecular phylogenetic analyses gave evidence for genetic reassortment in the evolution of the virus species. Moreover, we amplified a DOBV-Aa nucleotide sequence from a DOBV-seropositive HFRS patient from Germany. This is the first molecular identification of human infection by DOBV in Central Europe and the first direct proof that a virus strain related to the DOBV-Aa lineage, carried by A. agrarius rodents, is able to cause HFRS. Under biosafety level 3 conditions, we have established a DOBV isolate named Slovakia (SK/Aa) from an A. agrarius animal captured in Slovakia. SK/Aa, as the only isolate clearly belonging to the DOBV-Aa lineage, can be taken as the representative of this virus lineage. The new virus isolate, in comparison to a DOBV-Af strain, was used for serotyping neutralising antibodies of HFRS patients in Central Europe by the use of a focus reduction neutralisation assay. Most patients'' sera exhibited a higher end-point titer towards SK/Aa suggesting that DOBV-Aa strains are responsible for most of the DOBV HFRS cases in this region. TULV is carried by European common voles (Microtus sp.). Its pathogenic potential for humans was rather unknown. We have described the first case of HFRS which can be associated with TULV infection. Moreover, TULV strains detected in M. arvalis near the home village of the patient in North-East Germany clustered with strains from Poland and represent a new, well-supported genetic lineage within the TULV species. In addition to DOBV and longer known Puumala virus, TULV is most likely an additional causative agent of HFRS in Central Europe.

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35

Inkala, K. (Krista). "Miten tulla taitavaksi ohjaajaksi?:konsultatiivinen ohjaustaitokoulutus osana henkilökohtaisen ohjausotteen kehittymistä." Master's thesis, University of Oulu, 2015. http://urn.fi/URN:NBN:fi:oulu-201504021264.

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Tämä pro gradu-tutkielma liittyy Oulun yliopiston kasvatuspsykologian klinikalla tehtävään ohjaus- ja vuorovaikutustaitojen tutkimukseen. Työ on toteutettu laadullisena tapaustutkimuksena, ja sen tavoitteena oli tutkia yhden kiertävän erityislastentarhaopettajan henkilökohtaisen ohjausotteen kehittymistä konsultatiivisen ohjaustaitokoulutuksen myötä. Tutkimuksessa tarkastellaan ohjaustaitojen teorioita hyödyntäen, millaisia taitavan ohjaajan elementtejä koulutettavan ohjaustoiminnassa ilmeni koulutuksen alussa ja lopussa, miten tyypillisiä nämä elementit hänen toiminnassaan olivat ja tapahtuiko ohjaajan toiminnassa muutosta koulutuksen aikana. Ohjaajan toimintaa pyrittiin lisäksi ymmärtämään paremmin tarkastelemalla millaisena koulutettava itse koki ohjaustilanteet ja koulutuksen. Tutkimusaineistona työssä oli klinikalla järjestetyn SOLMU-koulutuksen videoaineistoa ja koulutettavan päiväkirjat, sekä koulutettavan kanssa käydyt keskustelut. Analyysi toteutettiin menetelmien triangulaatio-periaatteella. Käytettyjä menetelmiä olivat systemaattinen havainnointi, merkityksen kategorisointi, jatkuvan vertailun menetelmä ja subjektitieteellisen lähestymistavan mukaisten perustelumallien rekonstruointi. Aineistosta löydettiin taitavan ohjauksen elementtejä ja ne jaettiin analyysin tuloksena lopulta neljään pääkategoriaan ja niitä täsmentäviin alakategorioihin. Neljä pääkategoriaa, jotka kuvaavat ohjaajan toimintaa olivat: kuunteleminen, tarkentaminen, läsnäolo- ja vuorovaikutus sekä johtaminen. Koulutettavan omien kuvausten pohjalta laadittiin tiivistykset, joista edelleen johdettiin koulutettavan toimintaa kuvaavia perustelumalleja. Saadut tulokset koulutettavan ohjaustoiminnan kuvaamisesta vahvistivat aiempia tutkimustuloksia sen suhteen, mitä ohjaaja istunnon aikana tekee. Ohjaajan toiminta oli myös joiltain osin erilaista koulutuksen alussa ja sen lopussa. Tutkimustulokset eivät suoraan kerro koulutuksen kehittäneen koulutettavan ohjaustaitoja, mutta toisella ohjauskerralla ilmeni kuitenkin ensimmäistä ohjauskeskustelua vähemmän ns. ”ei-toivottuja” ohjauksen piirteitä. Tutkimustulokset ovat tämän tutkimuksen osalta luotettavia. Tämän tutkimuksen perusteella ei kuitenkaan voida sanoa yleisesti mitään esimerkiksi koulutuksen vaikuttavuudesta tai siitä, mihin asioihin ohjaustaitokoulutuksella voidaan ohjaajan toiminnassa vaikuttaa. Tulokset tulee nähdä yhtenä mahdollisena mallina yhdestä osasta henkilökohtaisen ohjausotteen muodostumisen prosessia. Jatkotutkimuksen aiheena tämän tutkimuksen pohjalta voisi olla esimerkiksi laajempi ja systemaattisesti toteutettu koulutuksen vaikuttavuuden tutkiminen esimerkiksi CROS-mittaria hyödyntäen tai laajempia perustelumalleja tehden.

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36

Ginjbaatar, Bilguun. "Creating an online shopping Website for "Chinguun-Tulga" office supply store /." Related Web site, 2007. http://www.chinguun-tulga.com/catalog/.

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37

Newman, Tiffanny Nicole. "ROLE OF TULA-FAMILY PROTEINS IN T CELL DRIVEN RESPONSES." Diss., Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/210733.

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Microbiology and Immunology
Ph.D.
The TULA-family consists of two proteins implicated in cellular regulation. TULA-1 is expressed in T-cells and is involved in apoptosis. TULA-2 is a ubiquitously expressed phosphatase that suppresses receptor-mediated signaling. T cells from mice lacking TULA-1 and 2 (double knockout, or dKO) are hypersensitive to TCR stimulation. This may be due to these proteins having a similar function working synergistically or dissimilar functions having a convergent effect. To understand functional interaction of these proteins we have characterized TULA-family knockout mice without and during an immune challenge. We show that CD4+ T cells of dKO mice have a characteristic CD45RB distribution, and that within the CD45RBlow subset effector/memory T cells are expanded only in dKO, but not in single knockouts (sKO) of either TULA-1 or TULA-2. However, CD4+ T cells of sKO and wild-type (WT) mice respond differently to TCR stimulation as seen using signaling and responses in vitro. To evaluate consequences of TULA deficiency in vivo, we utilized two mouse models of inflammatory bowel disease: TNBS-induced colitis and colitis induced by the adoptive transfer of CD45RBhigh CD4+ T cells. Studies utilizing TNBS indicate that deficiency of any TULA-family protein exacerbates TNBS-induced colitis. Likewise, dKO CD45RBhigh CD4+ T cells were significantly more colitogenic than cells from WT mice in the transfer model. Taken together, our data indicate that TULA-family proteins are key to the physiological regulation of T-cell reactivity that drives intestinal inflammation.
Temple University--Theses

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38

Korja, E. K. (Emma-Katariina). "Vokaalivartaloiden yleistyminen verbien nähdä, tehdä, tulla, mennä, purra ja surra A-infinitiiveissä." Bachelor's thesis, University of Oulu, 2019. http://urn.fi/URN:NBN:fi:oulu-201902021123.

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Tutkin kandidaatintutkielmassani vokaalivartaloiden yleistymistä verbien nähdä, tehdä, tulla, mennä, purra ja surra A-infinitiiveissä. Vokaalivartaloiden yleistyminen on ilmiö, jossa yleiskielen mukaisten konsonanttivartaloiden rinnalla on alkanut näkyä myös vokaalivartaloisia muotoja. Tarkastelen, esiintyykö vokaalivartaloisia A-infinitiivejä enemmän yleisemmissä vai harvinaisemmissa perussanoissa. Lisäksi tarkastelen, millaisissa syntaktisissa tehtävissä vokaalivartaloistuneet A-infinitiivit esiintyvät. Olen kerännyt aineistoni Korp-tietokannan Suomi24- ja Ylilauta-sivustojen keskustelupalstoja sisältävistä korpuksista. Aineistossani on yhteensä 408 vokaalivartaloisen A-infinitiivin sisältävää esiintymää. Havaitsin, että eniten vokaalivartaloisia A-infinitiivejä esiintyy nähdä-verbillä, joka on tutkimistani verbeistä yleisempien perussanojen joukossa. Muiden verbien osalta muotoja esiintyy aineistossani enemmän harvinaisemmissa kuin yleisemmissä perussanoissa. Vokaalivartaloisten A-infinitiivien syntaktisista tehtävistä yleisin on aineistossani verbiketju. Lisäksi A-infinitiivit esiintyvät aineistossani subjektina, objektina, nominin määritteenä, erilaisina irrallisina lausekkeina sekä erilaisissa nesessiivirakenteissa.

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Sirviö, M. (Maria). "Konsonanttivartalosta vokaalivartaloon verbien purra, surra, tulla ja mennä nut- ja tu-partisiipeissa." Bachelor's thesis, University of Oulu, 2018. http://urn.fi/URN:NBN:fi:oulu-201802081186.

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Kandidaatintutkielmani aihe on vokaalivartaloiden yleistyminen verbien tulla, mennä, purra ja surra NUT- ja TU-partisiipeissa. Yleiskielisesti NUT-partisiippi esiintyy esimerkiksi surra-verbissä muodossa surrut, mutta vokaalivartaloistumisen johdosta on yleistymässä muoto surenut. Tarkastelen lause- ja lausekeyhteyksiä, joissa vokaalivartaloisia muotoja esiintyy sekä sitä, onko vokaalivartaloistuminen yleisempää harvinaisemmissa kuin yleisemmissä perussanoissa. Valitsin verbit purra ja surra, koska ne ovat harvinaisempia perussanoja sekä verbit tulla ja mennä, koska ne ovat yleisempiä perussanoja. Aineistoni on kerätty Korpin Suomi24- ja Ylilauta-keskustelupalstoilta. Yhteensä aineistossa on 194 vokaalivartaloista esiintymää. Tutkielmani havaintona on, että vokaalivartaloiset muodot ovat yleisempiä harvinaisemmissa perussanoissa. Tämän lisäksi tutkielmassani selvisi, että vokaalivartaloiset NUT- ja TU-partisiipit esiintyvät liittomuotoina, verbiliittoina, adjektiivimaisina, referatiivirakenteessa, temporaalirakenteessa tai substantiivilausekkeen tehtävissä (esimerkiksi objektina).

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40

Rai, Lalita. "Tulsi `apotan` ka kavyakritiharuko bislesanatmok adhyayan तुलसी 'अपतन' -का काब्यकृतिहरुको विश्लेषणात्मक अध्ययन." Thesis, University of North Bengal, 2006. http://hdl.handle.net/123456789/1696.

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41

Sullivan, Mark. "The Maya origin of a Mexican god the iconographic primacy of Tezcatlipoca at Chichén Itzá, Yucatan over Tula, Hidalgo; and its possible derivation from God K--K'awil /." Orlando, Fla. : University of Central Florida, 2009. http://purl.fcla.edu/fcla/etd/CFE0002906.

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42

Slusser, Andrea. "DISCERNING MIGRATION IN THE ARCHAEOLOGICAL RECORD: A CASE STUDY AT CHICHÉN ITZ&Aacute." Master's thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2902.

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Migration, as a theory to explain aspects in the archaeological record, has fallen out of favor in Mesoamerican archaeology, possibly due to a lack of a standard definition or description of migration. Migration as an explanation of change in Maya civilizations has been around since the 1950's and the culture-history era of American archaeology. Since the early 1990's, migration has been treated as a process, one that can be discerned in pre-literate cultures as well as historical ones. Models of the migration process are being developed and tested. One type of migration, elite dominance migration, is a particularly suitable process to study in Mesoamerica. A model of elite dominance migration might include the following attributes: advance contact by the migrating culture, migration to a center, maintenance of contact with the sending population, spatial concentration of the incoming population, migration of a selected population of elites, and a cause or push factor. To find these attributes, the receiving population is studied to determine if there are multiple changes in the material record consistent with an intrusion of an outside group. And, there should be a rough chronological correlation between the sending and receiving populations. The Maya site of Chichén Itzá is a classic case study, and provides a starting point as a possible receiving population of an elite dominance migration. There is an abundance of scholarship devoted to the question of the relationship between Chichén Itzá and Tula, Hidalgo, in Central Mexico. The iconographic similarities between the two sites are numerous and have been thoroughly discussed in the literature. But, there is much more evidence that should be examined in applying a model of elite dominance, such as architecture, artifacts (including ceramics and obsidian), burial and caching practices, and site configuration. Comparing all of these categories at the two sites, one reaches two conclusions: there are multiple lines of evidence for change in the material record across the spectrum of categories at Chichén Itzá, and, to a lesser extent, at Tula, Hidalgo, indicating a population intrusion. And, secondly, there are abundant similarities in architecture, caching practices, ceramics, and other aspects of the material record that support the assertion of strong contacts between the two sites. Applying the model of elite dominance migration to Chichén Itzá, the majority of the markers for this type of migration can be seen in the material record of the site, as well as the site of Tula, Hidalgo. Chichén Itzá has the attributes of a receiving population, with an elite dominance migration of Central Mexican people taking place there, either from Tula, Hidalgo or from a third, as yet unspecified site that impacted both Chichén Itzá and Tula.
M.A.
Department of Anthropology
Sciences
Anthropology MA

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43

Aguilar, Mario Ignacio. "Current religious practices and generational patterns among the Waso Boorana of Garba Tulla Kenya." Thesis, SOAS, University of London, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309957.

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44

Klempa, Boris. "Dobrava and Tula hantaviruses from Central Europe molecular evolution and pathogenic relevance /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=974160334.

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45

Ambrogio, Sofia <1991&gt. "Uno studioso nella Cina degli anni '70 I viaggi di Vincenzo Tusa." Master's Degree Thesis, Università Ca' Foscari Venezia, 2019. http://hdl.handle.net/10579/15280.

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Questo elaborato affronta il tema delle esperienze di viaggio nella Cina degli anni '70 da parte di studiosi italiani, prendendo in esame i tre viaggi che l’archeologo Vincenzo Tusa compì in quegli anni. Per poter inquadrare e dare il giusto valore a ciò che scrive lo studioso, si è descritto prima il panorama e gli sviluppi storico-politici dei rapporti tra Italia e Cina di quegli anni, procedendo poi col dare uno sguardo alle esperienze di altri studiosi italiani che, dagli anni successivi alla fondazione della RPC in avanti, ebbero l'opportunità di visitare il paese. I tre viaggi di Tusa risultano di particolare interesse perché compiuti in tre grandi momenti diversi, che vanno dalla Rivoluzione Culturale alla denuncia della banda dei quattro, per poi concludersi col terzo viaggio in una Cina che si affaccia agli anni '80. I primi due viaggi, rispettivamente nel 1973 e 1976 sono da inquadrare in un periodo permeato da una forte propaganda socialista, nel quale gli studiosi stranieri subiscono inevitabilmente il fascino della Cina di Mao; il paese del terzo viaggio risente delle vicissitudini trascorse e appare agli occhi dello studioso, che nel 1981 può finalmente recarsi in Cina nelle vesti ufficiali di archeologo, profondamente cambiata. Guardare il paese attraverso la lente critica dell’archeologo ci restituisce tre fotografie molto differenti della Cina, soprattutto perché Tusa riesce a non abbandonare lo spirito curioso tipicamente archeologico di chi è abituato ad investigare sotto la superficie alla ricerca di ciò che è stato.

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46

Bonini, Eduardo Cunha. "As tramas do cinema de Peter Greenaway: processos de criação em The Tulse Luper Suitcases." Pontifícia Universidade Católica de São Paulo, 2010. https://tede2.pucsp.br/handle/handle/4239.

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Made available in DSpace on 2016-04-26T18:10:25Z (GMT). No. of bitstreams: 1 Eduardo Cunha Bonini.pdf: 2104355 bytes, checksum: 67322b414b45e6ef2f107499eb3bcd02 (MD5) Previous issue date: 2010-10-22
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
The purpose of this research is to study the creative processes manipulated by filmmaker Peter Greenaway in the construction of the project The Tulse Luper Suitcases. In this, one can find, in a full relational dialogue, movies, sites, live cinema performances, exhibitions, on line games, books, etc, posing as a complete potential system, a work in progress, whose limits between Medias that forge it are diluted. Our main goal is to understand how the project is structured and organized in a way that has made possible building a cross-media work closer to contemporary expressive forms. In this end, we have utilized the author s interviews and texts, from which we have removed the clues of his creative process. In order to achieve this goal, we have sought theoretical and methodological support in the theory of critical processes proposed by Cecilia Salles, which understands the creation process as a network construction. We have also established a dialogue on these arguments with some film expertises (DELEUZE, DUBBOIS, AUMONT, XAVIER), digital-medias theorists (MANOVICH, MACHADO) as well as some reviewers that have analyzed the work of this filmmaker. The concepts of encyclopedia and database-aesthetics, the later as it was proposed by Lev Manovich, have been used as drivers for the reflections over Peter Greenaway s creative procedures
A pesquisa tem por objeto de estudo os processos de criação operados pelo cineasta Peter Greenaway na construção do projeto The Tulse Luper Suitcases. Neste se encontram, em pleno diálogo relacional, filmes, sites, performances de live cinema (VJing), exposições, jogos on-line, livros, etc, que se apresentam como um sistema em plena potência, um work in progress, cujos limites entre as mídias que o constituem se encontram diluídos. O objetivo é compreender como este projeto é estruturado e organizado, de modo a formar uma obra cross-media que se aproxima das formas expressivas da contemporaneidade, a partir das entrevistas realizadas com autor e nos textos produzidos por ele, de onde retiramos as pistas acerca de seu processo criativo. Para tanto, buscamos sustentação teórico-metodológica na crítica de processos proposta por Cecília Salles, que parte do conceito de criação como rede em construção. Foi também estabelecido o diálogo destas discussões com alguns teóricos do cinema (DELEUZE, DUBBOIS, AUMONT, XAVIER), das mídias digitais (MANOVICH, MACHADO), assim como críticos que analisaram a obra deste cineasta. Os conceitos de enciclopédia e de estética de banco de dados, este último, da forma como propõe Lev Manovich, serão utilizados como direcionadores das reflexões sobre os procedimentos de criação de Peter Greenaway

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47

Hunger, Olga. "Anpassung der landwirtschaftlichen Unternehmensführung an die marktwirtschaftlichen Rahmenbedingungen in der Russischen Föderation - untersucht am Beispiel des Gebiets Tula /." Berlin : Mensch & Buch-Verl, 2003. http://www.gbv.de/dms/zbw/378200631.pdf.

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48

Back, Steven H. "Tula---2| A novel protein tyrosine phosphatase that regulates osteoclast differentiation and function." Thesis, Temple University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3623106.

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The human skeleton is a dynamic organ that serves multiple functions to maintain normal physiology and health. It protects vital organs, provides support for movement, houses marrow and maintains calcium homeostasis. The skeleton is maintained by the work of two cells with opposing functions: osteoblasts, cells that synthesize organic bone matrix and osteoclasts that degrade and resorb it. These cells interact with one another in a tightly regulated process known as the bone remodeling cycle. This cycle maintains the health of bone by removing and replacing weak or damaged bone and responding to stress loads by remodeling portions of the skeleton that require reinforcement. Osteoblasts differentiate from mesenchymal stem cells and respond to hormonal stimuli by synthesizing and secreting cytokines necessary for osteoclast differentiation. Osteoblasts may become embedded within mineralized matrix, becoming osteocytes, cells that can sense changes in mechanical loading and facilitate localization of the remodeling cycle. Osteoclasts differentiate from hematopoietic stem cells (HSC) when the cell surface receptors, c-FMS and RANK, are activated by ligands produced by osteoblasts, M-CSF and RANKL respectively. In addition to c-FMS and RANK stimulation, another calcium-mediated, co-stimulatory pathway must be activated to ensure proper osteoclast differentiation. This pathway is activated by two immunoreceptors, OSCAR and TREM-2 that interact with adaptor proteins termed FcRγ and DAP12 respectively. These adaptor proteins harbor immunoreceptor tyrosine-based activation motifs (ITAM), which exist on their cytoplasmic tail. Once the immunoreceptors are triggered, specific tyrosines within the ITAM motifs become phosphorylated and act as docking points for the tyrosine kinase, Syk. Once bound, Syk autophosphorylates and acts on its downstream targets. Syk dephosphorylation is, therefore, necessary to attenuate this signal to prevent over activation of osteoclasts. Recently, a novel tyrosine phosphatase, T-cell Ubiquitin ligand -2 (TULA-2) has been shown to dephosphorylate specific phosphotyrosine residues on Syk in various systems and has shown an increased specificity to dephosphorylate tyrosine 352. The goal of this project is to determine how TULA-2 mediated dephosphorylation of Syk regulates osteoclast differentiation and function. TULA-2 is a member of the TULA family of proteins, TULA and TULA-2. In spite of a significant homology and similar domain organization between TULA and TULA-2, only TULA-2 has significant phosphatase activity. Furthermore, whereas TULA is expressed only in lymphocytes, TULA-2 is expressed in most tissues albeit a higher level of expression is seen in cells of hematopoietic origin. In vivo analysis including Micro-computed tomography (Micro CT) and histomorphometry indicated that mice that lack both TULA and TULA-2 (DKO) have decreased bone mass compared to wild-type (WT) counterparts. An in vitro cell differentiation assay revealed that a larger population of osteoclast-like cells (OCL) could be cultivated from bone marrow isolated from DKO mice compared to OCL derived from WT bone marrow. An in vitro resorption pit assay revealed that DKO osteoclasts could resorb bone at a faster rate than WT counterparts. Additionally, over-expression of phosphatase-dead TULA-2 in WT osteoclasts increased the ability of the cells to resorb bone. At the molecular level, activation of the co-stimulatory pathway revealed increased tyrosine phosphorylation of Syk 352 in DKO pre-osteoclasts when compared to phosphorylation of Syk isolated from WT pre-osteoclasts. Cumulatively, the above data indicates that the absence of TULA-2 results in an increased signaling response leading to a larger population of hyperactive osteoclasts, which contributes to decreased bone mass in mice. These data suggest that the phosphatase activity of TULA-2 is required for negative regulation of bone resorption.

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49

Back, Steven. "TULA-2: A Novel Protein Tyrosine Phosphatase That Regulates Osteoclast Differentiation and Function." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/254886.

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Cell Biology
Ph.D.
The human skeleton is a dynamic organ that serves multiple functions to maintain normal physiology and health. It protects vital organs, provides support for movement, houses marrow and maintains calcium homeostasis. The skeleton is maintained by the work of two cells with opposing functions: osteoblasts, cells that synthesize organic bone matrix and osteoclasts that degrade and resorb it. These cells interact with one another in a tightly regulated process known as the bone remodeling cycle. This cycle maintains the health of bone by removing and replacing weak or damaged bone and responding to stress loads by remodeling portions of the skeleton that require reinforcement. Osteoblasts differentiate from mesenchymal stem cells and respond to hormonal stimuli by synthesizing and secreting cytokines necessary for osteoclast differentiation. Osteoblasts may become embedded within mineralized matrix, becoming osteocytes, cells that can sense changes in mechanical loading and facilitate localization of the remodeling cycle. Osteoclasts differentiate from hematopoietic stem cells (HSC) when the cell surface receptors, c-FMS and RANK, are activated by ligands produced by osteoblasts, M-CSF and RANKL respectively. In addition to c-FMS and RANK stimulation, another calcium-mediated, co-stimulatory pathway must be activated to ensure proper osteoclast differentiation. This pathway is activated by two immunoreceptors, OSCAR and TREM-2 that interact with adaptor proteins termed FcRγ and DAP12 respectively. These adaptor proteins harbor immunoreceptor tyrosine-based activation motifs (ITAM), which exist on their cytoplasmic tail. Once the immunoreceptors are triggered, specific tyrosines within the ITAM motifs become phosphorylated and act as docking points for the tyrosine kinase, Syk. Once bound, Syk autophosphorylates and acts on its downstream targets. Syk dephosphorylation is, therefore, necessary to attenuate this signal to prevent over activation of osteoclasts. Recently, a novel tyrosine phosphatase, T-cell Ubiquitin ligand -2 (TULA-2) has been shown to dephosphorylate specific phosphotyrosine residues on Syk in various systems and has shown an increased specificity to dephosphorylate tyrosine 352. The goal of this project is to determine how TULA-2 mediated dephosphorylation of Syk regulates osteoclast differentiation and function. TULA-2 is a member of the TULA family of proteins, TULA and TULA-2. In spite of a significant homology and similar domain organization between TULA and TULA-2, only TULA-2 has significant phosphatase activity. Furthermore, whereas TULA is expressed only in lymphocytes, TULA-2 is expressed in most tissues albeit a higher level of expression is seen in cells of hematopoietic origin. In vivo analysis including Micro-computed tomography (Micro CT) and histomorphometry indicated that mice that lack both TULA and TULA-2 (DKO) have decreased bone mass compared to wild-type (WT) counterparts. An in vitro cell differentiation assay revealed that a larger population of osteoclast-like cells (OCL) could be cultivated from bone marrow isolated from DKO mice compared to OCL derived from WT bone marrow. An in vitro resorption pit assay revealed that DKO osteoclasts could resorb bone at a faster rate than WT counterparts. Additionally, over-expression of phosphatase-dead TULA-2 in WT osteoclasts increased the ability of the cells to resorb bone. At the molecular level, activation of the co-stimulatory pathway revealed increased tyrosine phosphorylation of Syk 352 in DKO pre-osteoclasts when compared to phosphorylation of Syk isolated from WT pre-osteoclasts. Cumulatively, the above data indicates that the absence of TULA-2 results in an increased signaling response leading to a larger population of hyperactive osteoclasts, which contributes to decreased bone mass in mice. These data suggest that the phosphatase activity of TULA-2 is required for negative regulation of bone resorption.
Temple University--Theses

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50

Chover, Lafarga Anna. "El cuarto de Tula. Erotismo y sexualidad en las narradoras cubanas del periodo especial." Doctoral thesis, Universitat de València, 2010. http://hdl.handle.net/10803/41729.

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Tula era el nombre familiar de Gertrudis Gómez de Avellaneda, por ello representa en primer lugar, el estado primigenio de la escritura de mujeres latinoamericanas, la Avellaneda profunda sobre la que se sustenta el mito y un lugar de excepción en un canon literario tradicionalmente masculinista. Esta es la primera razón por la que Tula da título a esta tesis, porque esta cubana universal representa el exilio forzado que han sido las escritoras en la historia de la literatura latinoamericana. El punto de partida es entonces un análisis del protagonismo definitivo que adquieren las narradoras cubanas durante la década de los noventa, precisamente cuando la isla atravesaba una de sus peores crisis económicas. El cuarto de Tula es, en este mismo sentido, una invitación a la conquista de nuevos espacios para las narradoras cubanas. Por supuesto, es un guiño al clásico de Virginia Wolf, una habitación propia que las cubanas han reformulado desde diferentes propuestas estéticas. De las Novísimas a las (Post)novísimas, la propuesta implícita en el título es asomarnos a la rehabilitación del espacio reivindicado por Woolf, ahora en un cuarto destartalado de la Habana Vieja, en pleno Periodo Especial. Por otro lado, el título hace referencia también al tema clásico popularizado por Buena Vista Social Club. Desde esta perspectiva adquiere el sema de un espacio fundado para la demanda del placer de Ellas. Así pues, en una segunda parte de la tesis se analiza un corpus de textos atendiendo a las distintas representaciones del erotismo y la sexualidad. Cada capítulo va hilvanando una trayectoria de estrategias que muestran los modos en que estas narradoras han ido conquistando la cama haciéndola suya a base de secretas perversiones y también desastres íntimos. El cuerpo se convierte en la narrativa de mujeres cubanas en una cartografía para la experimentación literaria y erótica. Pero antes de atender al tema del erotismo en la última producción de mujeres cubanas devenía fundamental contextualizar el corpus en la red de intercambios estéticos, aparejados a las más recientes transformaciones de la sociedad cubana y del imaginario simbólico de la Revolución. Un proceso de profunda renovación de la cuentística nacional que, en el nivel discursivo de la postmodernidad, se traduce en un intenso proceso de experimentación formal y de asunción creativa de diversas corrientes del pensamiento y el arte contemporáneo. Entre las autoras destacadas en el corpus adquieren especial relevancia Anna Lidia Vega Serova y Ena Lucía Portela. En primer lugar, la narrativa de Anna Lidia Vega Serova se vislumbra como una radicalización de la propuesta discursiva noventina. A ella se dedica el capítulo 4 –El Erotismo Sucio de Anna Lidia Vega Serova–, en relación al discurso narrativo sobre la marginalidad cubana, que la crítica situación del Periodo Especial parece favorecer. Narraciones en tono realista, pero de un Realismo Sucio –líquido, postmoderno–, en las que el erotismo se perfila en una sucesión de escenas de sexo explícito que, no obstante, se desdibujan bajo el conflicto psicológico de los personajes. Se trata de un fenómeno literario netamente influenciado por la estética norteamericana del Dirty Realism. Por su parte, la narrativa de Ena Lucía Portela cobra protagonismo en los capítulos 6 y 7, a partir de una selección de sus cuentos, sin por ello desatender la referencia a sus novelas. El análisis está organizado en dos grandes vertientes temáticas. Por un lado, el título del capítulo 6 –“Ena Lucía Portela para una poética del erotismo. Las miradas del placer”–, hace alusión al juego de miradas que despliega la narrativa porteliana. La mirada falocéntrica en “Desnuda bajo la lluvia” (1999), y el voyaurismo femenino en “Un loco dentro del baño” (1999). Textos que convergen en un despliegue estratégico de miradas, a partir del cual, el acto de mirar y ser mirado se convierte en una clave temática que otorga poder erótico a la mirada de la mujer. Finalmente, esta tesis no podía llegar a su fin, sin un capítulo específico dedicado al homoerotismo femenino, sin perder de vista las esenciales aportaciones de los escritores varones al homosexualismo literario. Desde Virgilio Piñera –de un modo u otro presente en todo el trabajo– y Lezama Lima, hasta el corte cronológico que representan Roberto Urías y Senel Paz en los noventa.
Tula was the family name of Gertrudis Gómez de Avellaneda, This is the primary reason why Tula is the namesake of this thesis, because this universal Cuban figure represents the forced exile of female writers in the history of Latin American literature. The starting point, then, is an analysis of the definitive roles as protagonists that female Cuban narrators received in the 1990s, precisely when the island was experiencing one of its worst economic crises. In the same sense, Tula’s Bedroom is an invitation for female Cuban narrators to conquer new spaces. It does, of course, pay homage to the classic character Virginia Woolf, a room in which Cuban women have reformulated from different aesthetic offerings. The implicit suggestion of the title is to break free from the rehabilitation of the space reclaimed by Woolf that occurred throughout the nineties and the years that followed, a space which had by that time become a shabby room in Old Havana at the height of the Período Especial. On the other hand, the title also references the popular song by Buena Vista Social Club. From this perspective one recognizes maining of a space created to satisfy women. Therefore, the second part of the thesis analyzes a body of work that deals with the distinct representations of eroticism and sexuality. Each chapter links back to a path of strategies that shows the ways in which these female narrators have conquered the beds of many men, possessing them with the help of secret perversions and intimate disasters. The body then converts the voice of Cuban women into a map of lyric and erotic experimentation. However, before discussing the theme of eroticism in the most recent work by these women, it is fundamental to contextualize this body of work [corpus] in the network of aesthetic exchanges that came about in the most recent transformations in Cuban society and in the symbolic imagination of the Revolution. A thorough renewal of the national storytelling (on the discursive level of Postmodernism), is translated into an intense formal experimentation and into a creative acceptance of diverse currents of thought and contemporary art. Among the outstanding authors of these works, Anna Lidia Vega Serova and Ena Lucía Portela are two of special relevance. Firstly, Anna Lidia Vega Serova’s narrative offers us a glimpse of the radicalism of the nineties discursive offerings. Chapter four – The Dirty Eroticism of Anna Lidia Vega Serova— is dedicated to her, in relation to the narrative about marginalization of Cuba, which the critical situation of the Special Period seems to favor. Narration with realistic tone (but of a dirty, liquid, postmodern realism), in which eroticism takes shape in a succession of explicit sex scenes, are blurred by the psychological conflicts of the characters. The chapter discusses this literary phenomenon, obviously influenced by the North American aesthetic of Dirty Realism. As for Ena Lucía Portela, her narrative becomes the subject of chapters six and seven, starting with a selection of her short stories, while not neglecting her novels. The analysis of her work is organized in two thematic slopes. On the one hand, the title of chapter six—“Ena Lucía Portela for a poetry of eroticism. The look of pleasure,”—alludes to the game of looks or glances that is deployed by Portela’s narrative, such as the phallic “glance” taken in “Naked Under the Rain” (1999) and the female voyeuristic “glance” made in “A Madman in the Bathtub” (1999). These texts converge in a display of fleeting looks or glances, from which, the act of watching and being watched becomes a thematic key that grants an erotic power to the woman’s sense of sight. Finally, this thesis would not be complete without a specific chapter dedicated to feminist homoeroticism, without losing sight of the essential contributions of male writers to literary homosexuality. These male literary counterparts include authors ranging from Virgilio Piñera (present throughout the entire work in one way or another) and Lezama Lima, to the chronological cut that Roberto Urías and Senel Paz represent in the nineties.

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