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Journal articles on the topic 'Tumor pathologies'

Author: Grafiati

Published: 7 December 2024

Last updated: 31 July 2025

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1

Mende, Klaus C., Theresa Krätzig, Malte Mohme, Manfred Westphal, and Sven O. Eicker. "Keyhole approaches to intradural pathologies." Neurosurgical Focus 43, no. 2 (2017): E5. http://dx.doi.org/10.3171/2017.5.focus17198.

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OBJECTIVESpinal tumors account for 2%–4% of all tumors of the central nervous system and can be intramedullary, intradural extramedullary, or extradural. In the past, wide approaches were used to obtain safe access to these tumors, as complete resection is the goal in treating most tumor entities. To reduce surgical complications due to large skin incisions and destabilizing laminectomies, minimally invasive approaches were established. In this study, the authors share their experience with mini-open approaches to intradural tumor pathologies.METHODSThe authors retrospectively reviewed cases i

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Parra Sanabria, Erika Alexandra, and Claudia Patricia Peña Vega. "Frequency of Oral and Maxillofacial Pathologies in Patients from 0 to 18 Years in the Fundación Hospital de la Misericordia Bogotá (Colombia), during the Period 2006-2014." Universitas Médica 59, no. 4 (2018): 1–9. http://dx.doi.org/10.11144/javeriana.umed59-4.fpom.

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Introduction: Oral pathologies that can occur in children are very diverse and require extensive knowledge to diagnose them. Objective: To describe the frequency of oral and maxillofacial pathologies that occurred in patients aged 0-18 years who attended the Fundación Hospital de la Misericordia (HOMI) in the period 2006-2014, in addition to relating the most frequent oral and maxillofacial pathologies with sociodemographic characteristics. Materials and Methods: Descriptive, cross-sectional study. The analysis of information was recorded of 277 clinical histories of the HOMI, in patients from

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3

Parodi, Silvio, and Tommaso Mancuso. "A General Overview of the Process of Carcinogenesis." Tumori Journal 82, no. 4 (1996): 291–301. http://dx.doi.org/10.1177/030089169608200401.

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A general synthetic overview of the process of carcinogenesis is presented. The following points are discussed: the uniqueness of tumor disease with respect to other pathologies; tumors viewed as a pathology of the transduction system of signals that regulate the communal life of the cells of multicell organisms; the tumor as a genetic disease of somatic cells; carcinogenesis as a multistage event; the fundamental role of physiologic and pathologic rhythms of cell proliferation in the modulation of tumor incidence; mechanisms entailed in the maintenance of genome integrity; mechanisms involved

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Wadhwa, Vibhor, Rashmi S. Thakkar, Nicholas Maragakis, et al. "Sciatic nerve tumor and tumor-like lesions—uncommon pathologies." Skeletal Radiology 41, no. 7 (2012): 763–74. http://dx.doi.org/10.1007/s00256-012-1384-7.

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Sımsık, Sedat, Bülent Hayri Özokutan, Haluk Ceylan, Abdullah Aydın, and Elif Güler. "Ovarian Pathologies in Childhood." European Journal of Therapeutics 16, no. 2 (2010): 1–4. http://dx.doi.org/10.58600/eurjther.2010-16-2-1239-arch.

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Ovarian diseases are not rare in childhood and some problems are encountered with in evaluation of ovarian pathologies such as existance of different terminologies, lack of pathological criteria and different types of tumor classiffications. 55 patients younger than 16 years who had ovarian disease were treated and followed up and then the results were evaluated retrospectively. Patients were seperated in 3 groups as ovarian torsions (n:21), neoplastic ovarian pathologies (n:19) and non-neoplastic ovarian pathologies (n:28). Most frequent clinical symptom was abdominal pain and most frequent c

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Saymeh, M., S. Khairy, A. Moreno, J. Rabski, S. Kilty, and F. Alkherayf. "P.145 The role of 5-ALA Fluorescence-guided surgery in non-glioma pathologies." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 52, s1 (2025): S49. https://doi.org/10.1017/cjn.2025.10292.

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Background: Fluorescence-guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) is a well-established tool for improving tumor visualization in glioma surgery. However, its applications in non-glioma pathologies remain underexplored and require further investigation. Methods: A retrospective review of patients who underwent FGS with 5-ALA between January 2022 and September 2024 was conducted to assess its utility in non-glioma tumors. Results: Among 232 FGS procedures, 13 (5.6%) involved non-glioma pathologies. We categorized our patients into three different levels: high, moderate, and no re

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Saxena, Suvinay, Drushi D. Patel, Ankur Shah, and Mrugesh Doctor. "Fat Chance for Hidden Lesions: Pictorial Review of Hoffa's Fat Pad Lesions." Indian Journal of Radiology and Imaging 31, no. 04 (2021): 961–74. http://dx.doi.org/10.1055/s-0041-1739383.

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AbstractHoffa's fat pad (HFP) is the most commonly afflicted among all the knee fat pads. Anterior knee pain is common in various pathologies of HFP, as it is richly innervated. A potpourri of the intrinsic and extrinsic pathologies and the tumors and tumor-like conditions affect HFP, and MRI remains the fundamental modality to assess them and provide a specific diagnosis.

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Zehra, Pınar Koc, Pınar Özcan Kara Pelin, Sezer Emel, Özcan Cengiz, Yaldız Mehmet, and Görür Kemal. "Squamous cell carcinoma associated granular cell tumor with progressive FDG accumulation." International Journal of Medical Reviews and Case Reports 3, no. 11 (2019): 777–78. https://doi.org/10.5455/IJMRCR.Granular-cell-tumor-FDG-uptake.

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Granular cell tumor is a usually benign rare tumor of middle age women with variable FDG uptake patterns. The case that we presented was the first in the literature as far as we know with presentation of two different concurrent pathologies and progressive FDG uptake. Since the case was considered unresectable the patients received further chemotherapy. The patients' PET/CT results showed progression under treatment.

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Rusda, Muhammad, Riza Rivany, Citra Lestari Hasibuan, Delfi Lutan, Dudy Aldiansyah, and Cut Adeya Adella. "IHC Expression Relationships MMP7 and VEGF With Normal Ovaries and Ovarian Pathologies." Sumatera Medical Journal 2, no. 1 (2019): 47–54. http://dx.doi.org/10.32734/sumej.v2i1.719.

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To investigate the association of MMP7 and VEGF expression with ovarian cancer, benign ovarian cysts, and normal ovaries. This study was analytical research with case-control design. In the study, IHC expression of MMP7 and VEGF was carried out on paraffin block of ovarian cancer tissue, benign ovarian cyst, and normal ovary. In 40 subjects with ovarian tumors, 17 patients were found with positive MMP7 expression. In the control group, no subjects were found with positive MMP7 expression. There was a significant relationship between MMP7 expression and ovarian tumor incidence. Meanwhile, in 40

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Topolyanskaya, S. V. "Tumor Necrosis Factor-Alpha and Age-Related Pathologies." Russian Archives of Internal Medicine 10, no. 6 (2020): 414–21. http://dx.doi.org/10.20514/2226-6704-2020-10-6-414-421.

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Modern concepts about the «inflammaging» and the role of subclinical inflammation in various age-associated pathology are described in the review. Particular attention is paid to the tumor necrosis factor-α, a key cytokine that plays an important role in the pathogenesis of chronic inflammatory diseases as well as in aging. The increased levels of tumor necrosis factor-α leads to the onset and progression of various diseases, to severity of frailty, to disability and mortality of elderly persons. Tumor necrosis factor-α affects different risk factors for cardiovascular diseases, contributes to

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Barros, Maurício Davidovich de, Camila Barbosa Amaral, Bárbara Paula dos Santos Batista, Juliana da Silva Leite, and Ana Maria Reis Ferreira. "HISTOPATHOLOGICAL ALTERATIONS IN CANINE TESTICLES: DO OLD DOGS PRESENT NEW TRICKS?" Revista Contemporânea 4, no. 7 (2024): e5272. http://dx.doi.org/10.56083/rcv4n7-215.

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Histopathological evaluation of excised testicules from dogs submitted to orchiectomy is adamant in veterinary medicine. Many diagnoses are described providing evidence for canine reproductive management improvement. The objective of this study was to evaluate histopathological findings from testicular samples submitted to a Federal University Veterinary Pathological Anatomy Laboratory, from dogs who underwent orchiectomy for different reasons, relating these patients’ profile to revised pathologies. 145 dogs were included, yielding 278 testicules and 335 histopathological diagnoses. The major

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Kumar, Atul, Ankur Patel, Radha Sarawagi, Rajesh Malik, Nadeem Ur Rahman, and N. Balaji. "Uncommon synovial pathologies." Future Health 2 (March 3, 2024): 44–51. http://dx.doi.org/10.25259/fh_16_2024.

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The synovium is a specialized tissue lining the synovial joints, bursae, and tendon sheaths of the body. It is affected by various localized and systemic disorders. Synovial diseases can be broadly classified as inflammatory, infectious, degenerative, proliferative, hemorrhagic, and neoplastic. Injuries to other structures within the joint, such as cartilage, may also be caused by pathological processes that affect the synovium. Early detection of synovial diseases is critical to avoid irreversible joint damage. Understanding the typical imaging features of synovial diseases can help in accura

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Belhamidi, M. S., B. Slioui, and A. Bensal. "PERITONEAL TUBERCULOSIS MIMIKING GASTROINTESTINAL STROMAL TUMOR." International Journal of Advanced Research 12, no. 01 (2024): 710–12. http://dx.doi.org/10.21474/ijar01/18175.

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Abdominal TB is a common site of extrapulmonary tubercilosis, and peritoneal tuberculosis (PTB) is one of the most common manifestations of abdominal tuberculosis. The diagnosis of PTB can be made based on a combination of clinical, radiological, histological, and laboratory tests. The diagnosis can be easy in the presence of ascites with peritoneal granulations. some forms of PTB can make a differential diagnosis with peritoneal or digestive tract pathologies. some forms of PTB can make a differential diagnosis with peritoneal or digestive tract pathologies. We report a case of primary mesent

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Shah, Amit, Kethesparan Paramesparan, Philip Robinson, and Winston J. Rennie. "Non-neoplastic Soft Tissue Tumors and Tumor-like Lesions." Seminars in Musculoskeletal Radiology 24, no. 06 (2020): 645–66. http://dx.doi.org/10.1055/s-0040-1713606.

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AbstractClinicians are commonly faced with patients presenting with a solitary palpable soft tissue mass. Most soft tissue lesions are benign, and not every mass is due to a neoplastic process. Many pathologies can mimic a malignant tumor. Despite appropriate clinicoradiologic assessment, these lesions can be mistaken for a soft tissue sarcoma and can lead to multiple investigations or an intervention, inconveniencing patients and leading to an increased health care cost. With the relevant clinical history, clinical examination, and specific imaging characteristics, the diagnosis can be narrow

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HAYLAZ, Emre, Çiğdem ŞEKER, Gediz GEDUK, Murat İÇEN, and Elif Aslı GÜLŞEN. "Retrospective Analysis of Oral and Maxillofacial Pathologies." Journal of Contemporary Medicine 12, no. 6 (2022): 877–83. http://dx.doi.org/10.16899/jcm.1187584.

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Objectives: The aim of this study is to analyze the biopsy results of oral and maxillofacial lesions and to discuss them in the accompanied by the literature. Material and Method: In the study, biopsy results of 644 patients who were admitted to Zonguldak Bülent Ecevit University Faculty of Dentistry, Department of Oral and Maxillofacial Radiology between 2016-2021 for various reasons and subsequently diagnosed with oral and maxillofacial pathology were retrospectively analyzed using digital archives. Age, gender, location of the lesions and pathological diagnoses of the patients were re

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Elouarith, Ihssan, Leila Benbella, Fouad Zouaidia, Ahmed Jahid, Zakia Bernoussi, and Kaoutar Znati. "Intracranial Solitary Fibrous Tumour: Case Report." Scholars Journal of Medical Case Reports 11, no. 08 (2023): 1454–57. http://dx.doi.org/10.36347/sjmcr.2023.v11i08.008.

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Intracranial solitary fibrous tumor is a rare mesenchymal tumour. The diagnosis is based on the histological study given the clinical and radiological character that can simulate other benign or malignant pathologies especially meningioma. We report the case of a patient with an intracranial solitary fibrous tumor. We aim to discuss the clinical, radiological, histological and immunohistochemical features of Intracranial solitary fibrous tumor as well as the new grading system reported in the fifth edition of the WHO classification of central nervous system tumours.

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Kuznetsov, S. A., V. V. Sizonov, I. I. Belousov, and A. S. Podrezova. "Kidney cancer in a 14-year-old child: a rare clinical case description." Urology Herald 12, no. 6 (2025): 59–66. https://doi.org/10.21886/2308-6424-2024-12-6-59-66.

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Kidney tumours are among the most common solid malignant pathologies in children, accounting for 6 % of all childhood malignancies. About 89 % of these tumors are nephroblastomas (Wilms' tumors). Renal cell carcinoma in children is extremely rare, representing less than 1 % of all renal tumor pathologies in childhood and adolescence. Given the rarity of this pathology in children and the small size of neoplasms in the renal parenchyma, differential diagnosis between renal cancer and cystic renal lesions can be challenging. This clinical case describes a successful treatment case of a 14-year-o

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Dias, Isabella Figueiredo, Leonado Gomes Baldoino, Herbert Hornig, Gabriel Ishibashi Tatibana Kazuo, Samira Monteiro Martins, and Rafael da Silva Sá. "FIBROADENOMA JUVENIL GIGANTE EM PACIENTE HEBIÁTRICO: RELATO DE CASO." Colloquium Vitae 12, no. 2 (2020): 42–46. http://dx.doi.org/10.5747/cv.2020.v12.n2.v295.

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Fibroadenoma is the most frequent breast tumor in women aged 10 to 20 years, a neoplasm characterized by a benign multiplication with rapid growth and usually in the form of a single lump. A clinical case report study was performed on a 12 year and 7 month old girl, who had a left breast tumor, occupying all its extension. When the tumor is larger than 5 cm or 500 g or when it occupies at least 80% of the breast is considered a giant juvenile fibroadenoma. The choice of tumor surgical excision is the best option for both diagnosis and treatment, due to the need for pathologic evaluation. It is

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Frantsiyants, E. M., E. I. Surikova, I. V. Kaplieva, et al. "Diabetes mellitus and cancer: a system of insulin-like growth factors." Problems of Endocrinology 67, no. 5 (2021): 34–42. http://dx.doi.org/10.14341/probl12741.

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Diabetes mellitus and malignant tumors are among the most common and complex diseases. Epidemiological studies have shown a strong relationship between these pathologies. The causality of this relationship has not yet been unambiguously established, but a number of probable biological mechanisms have been proposed to explain it through the effects of hyperglycemia, hyperinsulinemia on the process of oncogenesis. An important role in this is played by the axis of insulin-like growth factors, their receptors and binding proteins (IGF / IGFR / IGFBP). The review provides data on the structural el

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Talay, Sureyya, Mustafa Abanoz, Mehmet Ali Kaygin, et al. "Glomus caroticum tumors: A case report of an operated giant carotid body tumor with a review of our experience in 47 patients." Open Medicine 5, no. 4 (2010): 411–16. http://dx.doi.org/10.2478/s11536-010-0015-8.

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AbstractGlomus caroticum tumors, usually used as an alternative term for carotid body tumor, are of neuroectodermal origin and a part of the extra adrenal neuroendocrine system pathologies. These abnormalities are the most frequently detected paraganglioma in the localization of the head and neck. In our report, we present a giant tumor mass on the left side which was operated on successfully with a review of our experience retrospectively. Between the dates of June 1995 and October 2009, 47 patients, all of which had a glomus caroticum tumor, underwent to surgery. Tumor presented a wide varie

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Villert, A. B., O. A. Bondyreva, S. V. Vtorushin, et al. "Embryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnostics." Tumors of female reproductive system 20, no. 4 (2024): 139–47. https://doi.org/10.17650/1994-4098-2024-20-4-139-147.

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Female adnexal tumor of Wolffian origin is an extremely rare and poorly studied tumor arising from remnants of Wolffian (mesonephric) duct and having an ambiguous malignancy potential. Immunohistochemical diagnostics of these tumors is important to exclude other pathologies. Interpretation of the prognosis is ambiguous. There are no clear standards for surgical or chemotherapeutic treatment. This is due to the lack of a sufficient number of observations and clinical studies. The article presents a clinical case of Wolffian duct tumor diagnosed in a 75-year-old patient, with a discussion of the

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Altınel, Faruk, Yonca Özvardar Pekcan, and Oya Nermin Sivrikoz. "SPINAL INTRADURAL EXTRAMEDULLARY TUMORS AND SIMILAR PATHOLOGIES: A SINGLE CENTER STUDY." MNJ (Malang Neurology Journal) 10, no. 2 (2024): 93–100. http://dx.doi.org/10.21776/ub.mnj.2024.010.02.01.

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Background: We wanted to analyze the neurological symptoms and prognosis of five spinal IDEM (intradural extramedullary) tumors cases diagnosed, and to emphasize that a spinal cord tumor can be found incidentally in evoluation of the proximal regions of the vertebral column in patients who were mistakenly operated for lumbar disc herniation on lumbar MRI, but whosesymptoms did not resolve. Objective: To emphasize the need for examinations such as MRI along the vertebral columna in patients with different spinal pathologies and whose symptoms and clinical signs do not improve. Methods: Patients

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Heiland, Dieter, Vidhya Ravi, Simon P. Behringer, Julian Wurm, Juergen Beck, and Oliver Schnell. "TMIC-52. REACTIVE ASTROCYTES AID THE EVOLUTION OF IMMUNOSUPPRESSIVE ENVIRONMENT AND DRIVE ONCOGENIC SIGNALING IN GLIOBLASTOMA." Neuro-Oncology 21, Supplement_6 (2019): vi259. http://dx.doi.org/10.1093/neuonc/noz175.1086.

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Abstract Reactive astrocytes are caused by multiple pathologies of the central nervous system, whereby they undergo distinct transcriptomic re-programming. Although the role of reactive astrocytes in some inflammatory diseases has been investigated, many central questions regarding the immunoregulatory functions of tumor-associated astrocytes and their crosstalk to microglia remain poorly understood. In our presented study, we purified astrocytes from various pathologies and different brain tumors to map the transcriptional landscape of reactive astrocytes. We identified the marker genes CHI3L

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Khan, Usman Qadir, Abid Raza, Qaimuddin Shaikh, Saadia Nazir, and Nadia Ambreen. "Pathologies associated with impacted maxillary canine tooth in patients presenting at a tertiary care hospital." International Journal of Research in Medical Sciences 9, no. 1 (2020): 34. http://dx.doi.org/10.18203/2320-6012.ijrms20205661.

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Background: The pathologies associated with impacted maxillary canine tooth presented as radiolucent, radiopaque and mixed radiolucent radiopaque lesions on radiographs and adenomatoid odontogenic tumor was the most common pathology associated with it followed by dentigerous cyst, odontoma and calcifying odontogenic cyst after histopathological confirmation. This study was planned to determine the frequency of pathologies associated with impacted maxillary canine tooth in patients presenting at a tertiary care hospital.Methods: This cross-sectional survey was conducted at Dental / Oral Surgery

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Günebakan, Çağlar, Selçuk Kuzu, Orhan Kemal Kahveci, Abdulkadir Bucak, and Şahin Ulu. "Retrospective Study on Clinico-Pathological Presentations and Complications of Parotidectomy." Bengal Journal of Otolaryngology and Head Neck Surgery 29, no. 1 (2021): 53–59. http://dx.doi.org/10.47210/bjohns.2021.v29i1.306.

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Introduction Salivary gland tumors are rarely seen. It constitutes approximately 3% of all head-neck tumors. 75-80% of these tumors originate from the parotid gland. In this study, 98 patients who underwent parotidectomy in a tertiary otorhinolaryngology clinic were analyzed retrospectively, the frequency of different pathologies and our treatment modalities for parotid masses are presented in the light of current literature. Materials and Methods In this study, 98 patients who underwent parotidectomy in our clinic between 2011 and 2018 were retrospectively analyzed, the frequency of different

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Tereshchenko, I. V., та P. E. Kayushev. "Tumor necrosis factor α and its role in pathologies". Russian Medical Inquiry 6, № 9 (2022): 523–27. http://dx.doi.org/10.32364/2587-6821-2022-6-9-523-527.

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Over the past years, the views on the role played by tumor necrosis factor α (TNF-α) in the body have changed. The aim of this review is to provide updates on TNF-α functions in various pathological conditions. While working on the review, the authors made search and analysis of full-text reviews and original articles in foreign (English) and Russian languages using such databases as eLIBRARY.RU, Google Scholar, Web of Science, Scopus and PubMed, mostly from 2018–2022. A priority was given to the original publications. TNF-α is a multifunctional pro-inflammatory cytokine which stimulates the p

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Rajakulasingam, Ramanan, Christine Azzopardi, Jennifer Murphy, et al. "Lesions of the Distal Phalanx: Imaging Overview." Indian Journal of Musculoskeletal Radiology 1 (August 18, 2019): 47–56. http://dx.doi.org/10.25259/ijmsr_13_2019.

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Lesions of the distal phalanx often pose a radiological dilemma as the differential diagnosis is potentially broad. Particularly for lytic lesions, there is a concern whether an underlying primary tumor or a metastatic deposit is present. Bone tumors of the hand are infrequent when compared to soft tissue tumors, and those involving the distal phalanx are very rare. Lesions of the distal phalanx may arise secondary to benign or malignant pathologies and may reflect primary or secondary tumors. The most common benign lesion is an enchondroma while the most frequent primary malignant lesion is c

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Fournel, Julien, Marc Hermier, Anna Martin, et al. "It Looks Like a Spinal Cord Tumor but It Is Not." Cancers 16, no. 5 (2024): 1004. http://dx.doi.org/10.3390/cancers16051004.

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Differentiating neoplastic from non-neoplastic spinal cord pathologies may be challenging due to overlapping clinical and radiological features. Spinal cord tumors, which comprise only 2–4% of central nervous system tumors, are rarer than non-tumoral myelopathies of inflammatory, vascular, or infectious origins. The risk of neurological deterioration and the high rate of false negatives or misdiagnoses associated with spinal cord biopsies require a cautious approach. Facing a spinal cord lesion, prioritizing more common non-surgical myelopathies in differential diagnoses is essential. A compre

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Salimoglu, Semra, Yuksel Dogan, and Semra Demirli. "The Other Breast Matters: Unexpected Pathologies in Oncoplastic Symmetry Procedures." ULUTAS MEDICAL JOURNAL 11, no. 2 (2025): 25. https://doi.org/10.5455/umj.20250505094058.

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Background: Oncoplastic breast surgery allows high-volume excision without compromising aesthetics. We aimed to analyze the probability of identifying high-risk malignant lesions in the contralateral breast. Materials and Methods: The study analyzed patients who underwent oncoplastic surgery between January 2000 and December 2023. All the patients underwent a preoperative assessment of the contralateral breast using mammography, ultrasonography, and breast MRI. Pathology reports were reviewed to identify malignant and high-risk lesions. Results: 38 patients had left-sided breast cancer, and 44

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Burke, William T., David L. Penn, Joseph P. Castlen, et al. "Prolactinomas and nonfunctioning adenomas: preoperative diagnosis of tumor type using serum prolactin and tumor size." Journal of Neurosurgery 133, no. 2 (2020): 321–28. http://dx.doi.org/10.3171/2019.3.jns19121.

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OBJECTIVEProlactinoma and nonfunctioning adenoma (NFA) are the most common sellar pathologies, and both can present with hyperprolactinemia. There are no definitive studies analyzing the relationship between the sizes of prolactinomas and NFAs and the serum prolactin level. Current guidelines for serum prolactin level cutoffs to distinguish between pathologies are suboptimal because they fail to consider the adenoma volume. In this study, the authors attempted to describe the relationship between serum prolactin level and prolactinoma volume. They also examined the predictive value that can be

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D’Amato Figueiredo, Marcos V., George A. Alexiou, George Vartholomatos, and Roberta Rehder. "Advances in Intraoperative Flow Cytometry." International Journal of Molecular Sciences 23, no. 21 (2022): 13430. http://dx.doi.org/10.3390/ijms232113430.

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Flow cytometry is the gold-standard laser-based technique to measure and analyze fluorescence levels of immunostaining and DNA content in individual cells. It provides a valuable tool to assess cells in the G0/G1, S, and G2/M phases, and those with polyploidy, which holds prognostic significance. Frozen section analysis is the standard intraoperative assessment for tumor margin evaluation and tumor resection. Here, we present flow cytometry as a promising technique for intraoperative tumor analysis in different pathologies, including brain tumors, leptomeningeal dissemination, breast cancer, h

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Matsuo, Ayaka, Ichiro Kawahara, Takeshi Hiu, et al. "BT-10 A RARE CASE OF RADIATION-INDUCED GLIOBLASTOMA 29 YEARS AFTER TREATMENTS OF GERMINOMA." Neuro-Oncology Advances 1, Supplement_2 (2019): ii38. http://dx.doi.org/10.1093/noajnl/vdz039.171.

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Abstract BACKGROUND Germinoma is one of the most radiosensitive tumors. Although radiotherapy (RT) can lead to long term-survival, it has the possibility to cause adverse effects. One of the more serious side effects include radiation-induced tumors that can contribute to a life-long prognosis. Case presentation A 40-year-old man was diagnosed with left basal ganglia germinoma at the age of 11 years old. Postoperatively, he received whole-brain radiotherapy 40Gy, focal radiotherapy 9.26Gy, and craniospinal irradiation. After these treatments, he was free from tumor recurrence or a secondary tu

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Zelchan, R. V., A. A. Medvedeva, O. D. Bragina, et al. "Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain." Bulletin of Siberian Medicine 20, no. 4 (2022): 131–42. http://dx.doi.org/10.20538/1682-0363-2021-4-131-142.

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The review analyzes the global experience in the application of nuclear medicine techniques for diagnosis of tumors and non-tumor pathologies of the brain. The main groups of radiopharmaceuticals currently used for imaging of malignant brain tumors and diagnosis of cognitive impairments and neurotransmitter system disturbances by means of single-photon emission computed tomography and positron emission tomography are described.Modern approaches to the application of methods for radionuclide diagnosis in neuro-oncology and neurology are compared, and the main trends in production of new, more s

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Ene, Cosmin-Victor, Ilinca Nicolae, Bogdan Geavlete, Petrisor Geavlete, and Corina Daniela Ene. "IL-6 Signaling Link between Inflammatory Tumor Microenvironment and Prostatic Tumorigenesis." Analytical Cellular Pathology 2022 (April 12, 2022): 1–10. http://dx.doi.org/10.1155/2022/5980387.

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Benign prostatic hyperplasia and prostate cancer are tumoral pathologies characterized by the overexpression of inflammatory processes. The exploration of tumor microenvironment and understanding the sequential events that take place in the stromal area of the prostate could help for an early management of these pathologies. This way, it is feasible the hypothesis that normalizing the stromal environment would help to suppress or even to reverse tumor fenotype. A number of immunological and genetic factors, endocrine dysfunctions, metabolic disorders, infectious foci, nutritional deficiencies,

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Ahmed, Alhassan Ali, Mohamed Abouzid, and Elżbieta Kaczmarek. "Deep Learning Approaches in Histopathology." Cancers 14, no. 21 (2022): 5264. http://dx.doi.org/10.3390/cancers14215264.

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The revolution of artificial intelligence and its impacts on our daily life has led to tremendous interest in the field and its related subtypes: machine learning and deep learning. Scientists and developers have designed machine learning- and deep learning-based algorithms to perform various tasks related to tumor pathologies, such as tumor detection, classification, grading with variant stages, diagnostic forecasting, recognition of pathological attributes, pathogenesis, and genomic mutations. Pathologists are interested in artificial intelligence to improve the diagnosis precision impartial

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ßahin, Mehmet, Emel ßahin, and Saadet Gümüşlü. "Cyclooxygenase-2 in Cancer and Angiogenesis." Angiology 60, no. 2 (2008): 242–53. http://dx.doi.org/10.1177/0003319708318378.

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Tumor angiogenesis is a process where new blood vessels are formed from preexisting ones, resulting in several pathologies. Solid tumors induce angiogenesis to obtain the required nutrients and oxygen. Otherwise, tumors do not grow beyond 2 to 3 mm in diameter. Cyclooxygenase-2, an inducible enzyme important in inflammation, catalyzes the production of prostanoids from arachidonic acid. Cyclooxygenase-2 plays an important role in several cancer types, including colorectal, gastric, prostate, breast, lung, and endometrial cancer. Besides, cyclooxygenase-2 has been implicated in the progression

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Laminou, L., M. Boubacar, H. Tyau-Tyau, HA Traoré, HY Abba Kaka, and A. Abdou. "Oculo-orbital tumor pathologies in Niger: Epidemiological, clinical, histological and therapeutic aspects over a period of 8 years." Journal Africain des Cas Cliniques et Revues 9, no. 2 (2025): 30–37. https://doi.org/10.70065/2592.jaccrafri.006l012304.

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Objective: To describe the epidemioclinical, therapeutic and histological particularities of oculo-orbital tumors at Zinder National Hospital (HNZ). Methodolgy: Descriptive study with retrospective data collection over a period of eight years (2015-2023). All patient records that had consulted the HNZ ophthalmology department for ocular tumor pathology with histopathological examination were included in the study. Incomplete records, pterygiums. Results: A total of 106 patient records with ocular tumours were collected. The male gender accounted for 81.82% with an average age of 19.27 years ±

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Mohammadi, Alireza M., Jason L. Schroeder, Lilyana Angelov, et al. "Impact of the radiosurgery prescription dose on the local control of small (2 cm or smaller) brain metastases." Journal of Neurosurgery 126, no. 3 (2017): 735–43. http://dx.doi.org/10.3171/2016.3.jns153014.

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OBJECTIVE The impact of the stereotactic radiosurgery (SRS) prescription dose (PD) on local progression and radiation necrosis for small (≤ 2 cm) brain metastases was evaluated. METHODS An institutional review board–approved retrospective review was performed on 896 patients with brain metastases ≤ 2 cm (3034 tumors) who were treated with 1229 SRS procedures between 2000 and 2012. Local progression and/or radiation necrosis were the primary end points. Each tumor was followed from the date of radiosurgery until one of the end points was reached or the last MRI follow-up. Various criteria were

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Jurić, Bernardica, Amir Ibukić, Slaven Čiček, Ivan Penavić, Davor Tomas, and Alma Demirović. "Massive endometriosis mimicking tumor – unusual cause of appendiceal intussusception." Libri Oncologici Croatian Journal of Oncology 51, no. 1 (2023): 31–36. http://dx.doi.org/10.20471/lo.2023.51.01.05.

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Appendiceal intussusception is a rare clinical entity that, in women of reproductive age, may be caused by endometriosis. We report a case of a 36-year-old woman presenting with abdominal pain. The patient underwent laparoscopic surgery, during which a suspicion of a cecal tumor was raised. A laparoscopic right hemicolectomy was performed. The patohistological exam showed an intussuscepted appendix, and the cause of the intussusception was massive endometriosis involving the colon, ileum, and appendix. It is important not to mistake appendiceal intussusception and appendiceal endometriosis wit

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Sahibzada, Sadia, Ajmal Khan, Tariq Sardar, Usama Aurangzeb, Nafeesa Afridi, and Intikhab Amanat. "Impacted Mandibular Third Molars Associated Pathologies." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 919–21. http://dx.doi.org/10.53350/pjmhs22168919.

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Purpose: The purpose of this research was to identify the most common and severe types of pathologic diseases surrounding impacted mandibular third molars using radiographic imaging. Cases and procedures: An analysis of past patients who had impacted mandibular molars extracted at Oral & Maxillofacial Surgery of Cat D Hospital Gara Tajik Peshawar. Impacted mandibular third molar radiographic lesions, patient age and gender were used as the study's outcome measures. Caries, pericoronal radiolucent areas, periapical radiolucent areas, odontomes, and external resorption of the roots of adjace

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Agrawal, Amit, Vissa Shanthi, Baddukonda Appala Ramakrishna, and Kuppili Venkata Murali Mohan. "Temporal gliosarcoma: case report and review of literature." Romanian Neurosurgery 22, no. 1 (2015): 112–16. http://dx.doi.org/10.1515/romneu-2015-0014.

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Abstract First characterized by Stroebe, the gliosarcomas are highly malignant and rare primary tumor of the brain composed of neoplastic glial cells in association with spindle cell sarcomatous elements (biphasic tissue patterns). In spite of being recognized as two different pathologies studies have not shown any significant differences between gliosarcoma and glioblastoma with regard to age, sex, size, clinical presentation, and median survival. In summary, gliosarcoma is an aggressive tumor with a propensity to recur and re-grow with poor outcome. Future studies are needed to understand th

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Espa, Giuseppe, Paola Feraco, Massimo Donelli, and Irene Dal Chiele. "A Fast and Efficient Semi-Unsupervised Segmentation and Feature-Extraction Methodology for Artificial Intelligence and Radiomics Applications: A Preliminary Study Applied to Glioblastoma." Electronics 12, no. 5 (2023): 1230. http://dx.doi.org/10.3390/electronics12051230.

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Brain tumors are pathologies characterized by a high degree of mortality. An early diagnosis of these pathologies could reduce mortality and limit the adverse effects of brain surgery. Computer-aided tomography (CT), and magnetic resonance imaging (MRI) are fundamental diagnostic methods. They offer lots of helpful information that help medical operators to make an early and effective diagnosis. However, a human operator must analyze and classify the enormous amount of data provided. This process is time-consuming, and sometimes the information is not directly visible to the human eye, leading

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Tillashaykhov, M., L. Gaziev, and D. Almuradova. "RESULTS OF THE ANALYSIS OF CLINICAL, MORPHOLOGICAL FACTORS FOR THE PROGNOSIS OF RENAL CELL CARCINOMA." ASJ 1, no. 56 (2021): 21–24. http://dx.doi.org/10.31618/asj.2707-9864.2021.1.56.146.

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This article analyzes the main clinical, morphological factors affecting the outcome of the disease, and determines their proportion. Favorable clinical and morphological signs were: absence of lymphovascular invasion, lymphocytic infiltration of the tumor, small tumor size, absence of concomitant pathology. Adverse prognosis factors include: lymphovascular invasion, absence of tumor infiltration by lymphocytes, large tumor size and severe concomitant pathologies.

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L.T., Gaziev N.E. Atakhanova N.I.Tursunova. "RESULTS OF THE ANALYSIS OF CLINICAL, MORPHOLOGICAL FACTORS FOR THE PROGNOSIS OF RENAL CELL CARCINOMA." EURASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES 2, no. 8 (2022): 18–25. https://doi.org/10.5281/zenodo.6968982.

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This article analyzes the main clinical, morphological factors affecting the outcome of the disease, and determines their proportion. Favorable clinical and morphological signs were: absence of lymphovascular invasion, lymphocytic infiltration of the tumor, small tumor size, absence of concomitant pathology. Adverse prognosis factors include: lymphovascular invasion, absence of tumor infiltration by lymphocytes, large tumor size and severe concomitant pathologies.

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Goncharov, Aviv Philip, Nino Vashakidze, and Gvantsa Kharaishvili. "Epithelial-Mesenchymal Transition: A Fundamental Cellular and Microenvironmental Process in Benign and Malignant Prostate Pathologies." Biomedicines 12, no. 2 (2024): 418. http://dx.doi.org/10.3390/biomedicines12020418.

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Epithelial-mesenchymal transition (EMT) is a crucial and fundamental mechanism in many cellular processes, beginning with embryogenesis via tissue remodulation and wound healing, and plays a vital role in tumorigenesis and metastasis formation. EMT is a complex process that involves many transcription factors and genes that enable the tumor cell to leave the primary location, invade the basement membrane, and send metastasis to other tissues. Moreover, it may help the tumor avoid the immune system and establish radioresistance and chemoresistance. It may also change the normal microenvironment

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Sierra, R., M. Bajka, and G. Székely. "Tumor growth models to generate pathologies for surgical training simulators." Medical Image Analysis 10, no. 3 (2006): 305–16. http://dx.doi.org/10.1016/j.media.2005.11.004.

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Djaladat, Hooman, Craig R. Nichols, and Siamak Daneshmand. "Mesenteric lymphadenopathy in patients with germ cell tumor." Journal of Clinical Oncology 30, no. 5_suppl (2012): 347. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.347.

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347 Background: Mesenteric lymphadenopathy may be secondary to inflammatory, infectious or tumoral pathologies. The most common malignancies causing mesenteric adenopathy are gastrointestinal and lymphoma. To the best of our knowledge, there are no reports of germ cell tumor (GCT) presenting with mesenteric adenopathy. Methods: Four patients with GCTs presenting with mesenteric adenopathies were treated in two academic centers (OHSU and USC) by a single surgeon since 2004. All pathologies were non-seminomatous GCT. Their presentation, clinico-pathologic findings and outcome are reviewed. Resul

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Yadav, Randhir Sagar, Ashik Pokharel, Shumneva Shrestha, et al. "Pancreatic Neuroendocrine Tumor with Benign Serous Cystadenoma: A Rare Entity." Case Reports in Oncological Medicine 2021 (August 4, 2021): 1–5. http://dx.doi.org/10.1155/2021/9979998.

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Mixed serous-neuroendocrine neoplasm constitutes pancreatic serous cystic neoplasms and pancreatic neuroendocrine tumor, two tumor components with different underlying pathologies. The differentiation of these tumors is important as the management and prognosis depend on the pancreatic neuroendocrine tumor component. We report a case of mixed serous-neuroendocrine neoplasm in a 47-year-old female who presented with epigastric pain abdomen for two years. Imaging studies, tumor markers, thorough systemic evaluation, surgical resection, histopathological examination, and timely follow-up constitu

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Vázquez-Borrego, Fuentes-Fayos, Venegas-Moreno, et al. "Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features." Cancers 11, no. 10 (2019): 1439. http://dx.doi.org/10.3390/cancers11101439.

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Pituitary neuroendocrine tumors (PitNETs) constitute approximately 15% of all brain tumors, and most have a sporadic origin. Recent studies suggest that altered alternative splicing and, consequently, appearance of aberrant splicing variants, is a common feature of most tumor pathologies. Moreover, spliceosome is considered an attractive therapeutic target in tumor pathologies, and the inhibition of SF3B1 (e.g., using pladienolide-B) has been shown to exert antitumor effects. Therefore, we aimed to analyze the expression levels of selected splicing-machinery components in 261 PitNETs (somatotr

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Frantsiyants, E. M., I. V. Kaplieva, E. A. Sheiko, et al. "Changes in electrical parameters of the heart in an experimental model of malignant tumor growth during of hyperthyroidism." Siberian Journal of Clinical and Experimental Medicine 39, no. 3 (2024): 156–63. http://dx.doi.org/10.29001/2073-8552-2024-39-3-156-163.

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Experimental and clinical studies demonstrate the possibility of modulating the development of malignant tumors in thyroid imbalance, in particular hyperthyroidism, which negatively affects the electrophysiology of the heart. In an experimental model of tumor growth during of hyperthyroidism, activation of the tumor was shown.Aim: To study electrophysiological parameters of the mouse heart at the initial stages of transplantable tumor growth during of hyperthyroidism.Material and Methods. In female mice of the C57BL/6 line (n = 20) was created a model of melanoma B16/F10 growth during of hyper

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