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Dissertations / Theses on the topic 'Type 4'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Sohm, Oliver Peter. "Optimisation of video coding algorithms for VLIW-type processors." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271859.

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2

Ashrafi, G. Hossein. "Mutational analysis of the transforming protein E8 of bovine papillomavirus type-4 (BPV-4)." Thesis, University of Glasgow, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263456.

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3

Korniotis, Nadia. "Expression studies of recombinant cAMP-specific phosphodiesterase type 4." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402537.

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4

Kaufman, Samuel 1981. "Delzant-type classification of near-symplectic toric 4-manifolds." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33096.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mathematics, 2005.<br>Includes bibliographical references (p. 65-66).<br>Delzant's theorem for symplectic toric manifolds says that there is a one-to-one correspondence between certain convex polytopes in ... and symplectic toric 2n-manifolds, realized by the image of the moment map. I present proofs of this theorem and the convexity theorem of Atiyah-Guillemin-Sternberg on which it relies. Then, I describe Honda's results on the local structure of near-symplectic 4-manifolds, and inspired by recent work of Gay-Symington, I describ

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5

Shim, Hyeseok. "Biology of Type 2 Phosphatidylinositol-5-Phosphate 4-Kinase." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:23845419.

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Type 2 phosphatidylinositol-5-phosphate 4-kinase (PI5P4K) converts phosphatidylinositol-5-phosphate to phosphatidylinositol-4,5-bisphosphate. Mammals have three genes, PIP4K2A, PIP4K2B and PIP4K2C that encode the enzymes PI5P4Kα, PI5P4Kβ and PI5P4Kγ respectively. Studies in mice showed that PI5P4Kβ is a negative regulator of insulin signaling (Lamia et al., 2004) and that co-deletion of Pip4k2b and Trp53 resulted in synthetic embryonic lethality (Emerling et al., 2013). Also, deletion of two alleles of Pip4k2a and one allele of Pip4k2b suppressed the appearance of tumors in Trp53-/- mice. Thes

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6

Larsson, Leo. "Carlson type inequalities and their applications." Doctoral thesis, Uppsala : Univ. : Matematiska institutionen, Univ. [distributör], 2003. http://publications.uu.se/theses/91-506-1654-4/.

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7

Beard, Matthew Brian. "A study of protein-protein interactions involving Type 4 phosphodiesterase." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301782.

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8

Alli-Balogun, Ganiyu Olabanji. "The cellular functions of mammalian type II phosphatidylinositol 4-kinases." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/10039515/.

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Type II phosphatidylinositol 4-kinases (PI4KIIs), PI4KIIα and PI4KIIβ, both catalyse phosphatidylinositol 4-phosphate (PI(4)P) synthesis and are implicated in the control of trafficking from the trans-Golgi network (TGN) and endosomal membranes. It has been suggested that these closely related isoforms perform redundant roles. This study addresses the issue of functional overlap, by studying the location of the PI(4)P pools synthesised by each isoform, the associated membrane trafficking routes and the functional consequences of loss of these PI4P pools. The TGN localisations of PI4KIIα and PI

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9

Vataj, Ramë. "Oxydation anodique de cavites coniques de type Calix [4] arene." Mulhouse, 2004. http://www.theses.fr/2004MULH0755.

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Le travail décrit dans ce mémoire constitue la première étude systématique entreprise jusqu'à ce jour sur l'oxydation électrochimique de calixarènes fonctionnarisés en milieu organique. Les méthodes électrochimiques utilisées (voltamétrie stationnaire sur électrode toumante, voltamétrie cyclique et coulométrie à potentiel contrôlé), associées à la spectroélectrochimie UV-visible in situ, ont permis de déterminer les paramètres cinétiques et électrochimiques, et établir le mécanisme d'oxydation de ces composés. Les résultats obtenus montrent que, dans tous les cas, l'oxydation électrochimique i

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10

Elfvin, Åkesson Karin. "Genetic analysis of type 1 diabetes /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-321-4/.

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11

Zago, Manola. "Cell transformation by the E5 protein of bovine papillomavirus type 4." Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394967.

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12

Araiza, Stephanie M. "Novel Phosphors Based on Ordered Olivine Type Metal Oxide CaYGaO 4." Thesis, California State University, Long Beach, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10837382.

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<p> Two series of novel phosphors based on parent compound CaYGaO<sub>4</sub> were developed. The first series was created by doping trivalent europium into the yttrium position in percentages ranging from 0.50–20. The samples exhibit one strong emission in the orange region of the visible spectrum one medium emission in the yellow and several weak emissions in the green and red. This series preforms well in elevated temperatures, which makes them good candidates for solid state lighting purposes. The second series was created by doping terbium into the yttrium position at percentages ra

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13

Macauley, Mavin Ekundayo Obafemi. "Metabolic effects of dipeptyl peptidase 4 inhibitor in type 2 diabetes." Thesis, University of Newcastle upon Tyne, 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701160.

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Insulin resistance and abnormal insulin secretion are central to type 2 diabetes. The relationships have been established between lipid accumulation in the liver and muscle and insulin resistance, and that of lipid accumulation in the pancreas and β cell dysfunction. Therefore it is vital to assess the effect of therapies on intra-organ lipid concentration. DPP-4 inhibitor vildagliptin is a new therapeutic agent in type 2 diabetes. Its known primary mechanism of action is to delay GLP-1 and GIP degradation, and enhance their endogenous concentration. GLP-1 and GIP increase the sensitivity of t

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14

Lindsay, Barbara. "Synthesis of structural probes for the phosphodiesterase (type 4) catalytic site." Thesis, Heriot-Watt University, 2008. http://hdl.handle.net/10399/2191.

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15

Snellman, A. (Anne). "Characterization of chain association in collagen types XII and XIII and other biochemical features of type XIII collagen using baculovirus-directed insect cell expression." Doctoral thesis, University of Oulu, 2000. http://urn.fi/urn:isbn:9514257464.

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Abstract Type XII minicollagen chain association was studied using baculovirus-directed insect cell expression. Since insect cells contain low endogenous prolyl 4-hydroxylase activity, the mechanism of the effect of prolyl hydroxylation on trimer formation in this collagen could be studied directly by adding recombinant baculoviruses directing the synthesis of prolyl 4-hydroxylase. Prolyl 4-hydroxylase was shown to be involved in the trimeric assembly process of type XII collagen through its α subunit, and thus through its hydroxylase activity. The transmembrane protein type XIII collagen was

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16

Frenette-Cotton, Rachelle. "Régulation du cotransporteur K+-Cl-de type 4 (KCC4) par la WNK lysine deficient protein kinase 4 (WNK4)." Doctoral thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/26600.

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Cette thèse de doctorat porte sur la régulation du cotransporteur K+-Cl- de type 4 (KCC4) par la « WNK lysine deficient protein kinase 4 » (WNK4), une sérine-thréonine kinase qui a été découverte en 2001. Le cotransporteur KCC4 fait partie de la famille des cotransporteurs cation-Cl- (CCC) qui compte neuf membres. Le cotransporteur KCC4, et les autres isoformes de type KCC, sont des protéines de surface qui couplent l’efflux du Cl- à celui du K+ de manière électroneutre. Ce faisant, ils régulent le Cl- intracellulaire (Cl-i), le volume cellulaire (Vi) et la réabsorption basolatérale du Cl- dan

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17

Montanez, Griselle Enid. "The Role of the sia and siu ABC-Type Transporters in Iron Utilization and Virulence in Streptococcus pyogenes." Digital Archive @ GSU, 2006. http://digitalarchive.gsu.edu/biology_diss/4.

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A limited understanding of iron uptake mechanisms is available for Streptococcus pyogenes, a hemolytic human pathogen capable of using a variety of hemoproteins in addition to ferric and ferrous iron. This study characterizes the transporters of iron-complexes siuADBG (for streptococcal iron uptake) and siaABC (for streptococcal iron acquisition). These ABC-type transporters are encoded by iron regulated operons and their protein products are homologous to components of heme and siderophore transporters found in both Gram-positive and Gram-negative bacteria. Mutants of the membrane permease

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18

Meade, Barry Jay. "THE TRANSMISSION DYNAMICS OF EQUINE HERPESVIRUS TYPE 1 (EHV-1) INFECTION IN OUTBREAKS CHARACTERIZED PREDOMINATELY BY NEUROLOGIC OR RESPIRATORY ILLNESS." UKnowledge, 2012. http://uknowledge.uky.edu/gluck_etds/4.

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Formalized epidemiological field investigations were conducted to compare and contrast the transmission dynamics of EHV-1 neurological disease among horses stabled at Churchill Downs Racetrack, Louisville, Kentucky and of EHV-1 respiratory illness among horses stabled in the student barn at Murray State University. Differences were assessed by means of statistical and mathematical modeling techniques applied to survey and biological data collected over the course of the respective disease events. Regression methods applied to survey data enabled the construction of a statistical model to predi

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19

Frenette-Cotton, Rachelle. "Analyses cinétiques d'un hétérooligomère formé des cotransporteurs K+ -CL- de type 2 (KCC2) et de type 4 (KCC4)." Thesis, Université Laval, 2010. http://www.theses.ulaval.ca/2010/27262/27262.pdf.

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20

Cooksey, Tonya. "Relationships between Mother's Body Type/Size, Attitude Towards Physical Activity and Daughter's Body Mass Index and Physical Activity Score in African Americans." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/nutrition_theses/4.

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The relationship between body mass index (BMI) and physical activity level of daughters and their mothers’ body type/size and attitude towards physical activity in African Americans was investigated. 51 subjects were recruited. Subjects completed the Short International Physical Activity Questionnaire (IPAQ) and an attitudinal questionnaire. Subjects’ height and weight were measured. Mother’s body type/size was found to be weakly associated with daughter’s BMI (r=0.28, p=0.051). Mother’s overall attitude towards physical activity was not associated with daughter’s IPAQ score. The results sugge

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21

Fazzi, Marco. "Higher-dimensional field theories from type II supergravity: Théories des champs à haute dimension résultant de la supergravité de type II." Doctoral thesis, Universite Libre de Bruxelles, 2016. https://dipot.ulb.ac.be/dspace/bitstream/2013/232901/4/main.pdf.

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Dans cette thèse, nous présentons des constructions explicites de la correspondance AdS/CFT dans le contexte de la théorie des cordes de type II. Ces constructions sont visées à mieux comprendre aspects de la physique nonperturbative de théories des champs superconformes à d = 6,5,4 dimensions. Dans la première partie de la thèse nous introduisons les systèmes de NS5-Dp-D(p+2)-branes de Hanany-Witten, au moyen desquels on peut construire théories des champs avec 8 supercharges. Quand p = 6, le système de NS5-D6-D8-branes permet de construire théories des champs superconformes à 6 dimensions, c

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22

Austin, Peter C. "Products of involutions in the Chevalley groups of type F(4)(K)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ27872.pdf.

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23

Hughes, David. "Pathogenesis of murid herpesvirus type 4 in its natural host, Apodemus sylvaticus." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425703.

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24

Evans, Louise Sarah. "Amido-pyrrole, isophthalamide andcalix[4]arene cleft-type receptors fpr anionic guests." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444970.

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25

Natchus, Michael George. "[4+1] cyclopentene annulation in the total synthesis of pentalenene type sesquiterpenes." Thesis, Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/50070.

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The generality of the [4+1] cyclopentene annulation was demonstrated by the total synthesis of (±)-pentalenene and its C-9 epimer which were prepared in a stereocontrolled manner in analogy with the synthesis of (±)-isocomene, (±)-hirsutene and (±)-pentalenic acid. The key features of this synthesis involved preparation of acid 161, its conversion to diazoketone 148, intramolecular cyclopropanation of this substance to vinylcyclopropane 163 and the vinylcyclopropane-cyclo pentene rearrangement of several derivatives of 195 to triquinanes 147, 146, 197, and 204. A detailed study of temperature,

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26

Weder, Christoph. "Synthese und Charakterisierung neuer Polyamide mit stabilen nichtlinear optischen Eigenschaften, basierend auf 2',5'-Diamino-4-(dimethylamino)-4'-nitrostilben /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10749.

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27

Wang, Zhaohui. "Type-specific human papillomavirus antibodies : detection, characterization and application in seroepidemiology /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3802-4/.

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28

Huh, Ahrin. "EXPRESSION OF HISTONE DEACETYLASE 4 AND HISTONE ACETYLTRANSFERASE 4 IN HUMAN MASSETER MUSCLE: RELATIONS TO FIBER-TYPE COMPOSITION IN PATIENTS WITH MALOCCLUSIONS." Master's thesis, Temple University Libraries, 2012. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/171954.

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Oral Biology<br>M.S.<br>Significant advances have been made in orthodontics and oral maxillofacial surgery for the diagnosis and treatment of dentofacial deformities. However, compared with bone, the effect of muscles of the craniofacial complex in the development of dentofacial deformities has received little attention. Recently, cellular and molecular studies of the musculoskeletal interactions have been used to investigate the etiology of dentofacial malocclusions. In this study, we tested for relationships that might exist between gene expression of the chromatin modifying enzymes histone

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29

Björklund, Susann. "What could a 4 temperament-based personality type system reveal about aid workers in the humanitarian field?" Thesis, Uppsala universitet, Teologiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-278815.

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The humanitarian sector is in need to prioritize its human resources. Inadequate recruitment processes, aid workers that enter the field unprepared, failed interrelationships and team dissatisfaction leads to poorer work quality, poorer health, and a high employee turnover that are costly for the field, and negative on the side of accountability to the beneficiaries of aid. In order to address these problems the study is investigating the use of a personality type system tool developed by the researcher, the 4mpt-system (4 major personality types-system),that tentatively is constructed as a to

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30

Karlsson, Håkan K. R. "Insulin signaling and glucose transport in insulin resistant human skeletal muscle /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-469-4/.

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31

Richard, Léa. "Détection et caractérisation moléculaire des rétrovirus d'origine simienne chez l'Homme : cas du virus foamy et du virus T-lymphotrope de type 4." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCC211/document.

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Les primates non-humains (PNH) sont un important réservoir de pathogènes et notamment de rétrovirus. Plusieurs agents infectieux ont émergé dans la population humaine à partir de ce réservoir animal, comme par exemple le virus de l’immunodéficience humaine ou le virus T lymphotrope humain (HTLV) de type 1 qui se sont répandus mondialement et causent de graves pathologies. L’émergence de rétrovirus chez l’Homme nécessite plusieurs étapes passant par la transmission primaire du virus du PNH à l’Homme, la persistance du virus dans l’organisme,la transmission secondaire inter-humaine et enfin sa d

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32

Nokelainen, M. (Minna). "Recombinant human collagens:characterization of type II collagen expressed in insect cells and production of types I-III collagen in the yeast Pichia pastoris." Doctoral thesis, University of Oulu, 2000. http://urn.fi/urn:isbn:9514257383.

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Abstract An efficient system for expressing recombinant human collagens is expected to have numerous scientific and medical applications, but this is difficult to achieve because most systems do not have sufficient levels of activity of prolyl 4-hydroxylase, the key enzyme of collagen synthesis. A recombinant form of human type II collagen, the main structural component of cartilage, was produced here in insect cells by coinfecting them with two baculoviruses, one coding for the proα chains of human type II procollagen, and the other for both the α and β subunits of human prolyl 4-hydroxylas

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33

Sandberg, Malin. "Calcium dynamics and vesicle-release proteins in a prion-infected neuronal cell line /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-245-4/.

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34

Cairney, Margaret. "The transformation biology of bovine papillomavirus type 4 in established and primary cells." Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297054.

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35

Togami, Hiroaki. "Comprehensive in vitro susceptibility analysis of simian retrovirus type 4 to antiretroviral agents." Kyoto University, 2013. http://hdl.handle.net/2433/179351.

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36

Bellatif, Moulay Fayçal. "Etude expérimentale de la colonisation du poulet par salmonella enteritidis type phagique 4." Poitiers, 1994. http://www.theses.fr/1994POIT2290.

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Le portage asymptomatique de salmonella est frequent chez les volailles. Salmonella enteritidis est devenu le serovar le plus frequemment associe aux toxi-infections alimentaires collectives provoquees apres la consommation de produits aviaires. L'etude experimentale comparative de la colonisation des poulets monoxeniques et gnotoxeniques a montre qu'une concentration minimale de salmonella enteritidis pt4 est necessaire pour coloniser le tube digestif du poulet hebergeant une microflore digestive. Cette microflore reduit cependant le nombre de s. Enteritidis dans l'intestin du poulet, mais n'

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37

Chabbi, Mohamed. "Synthese d'antiviraux potentiels de type 4'-c-nucleosides et de cyclo-nucleosides imidazoliques." Amiens, 1996. http://www.theses.fr/1996AMIE0110.

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Le 3-(1',2'-0-isopropylidene-beta-l-threofuranos-4'-yl)maleimide et ses derives 3'-0-benzyle, 3'-desoxy et 3'-0-methyle, analogues de la showdomycine, ont ete synthetises a partir du d-glucose avec comme derives cles des composes aldehydiques en c-5 (obtenus en 4 a 5 etapes avec un rendement de 33 a 58%). A partir de ces derniers la base maleimidique a ete construite en 3 etapes : amidation, oxydation puis condensation d'un phosphorane. La condensation, selon wittig, conduit aux alcenes cis et trans dont les proportions dependent de l'encombrement de la position c-3 du monosaccharide. Apres cy

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38

Vaezzadeh, Majid. "Étude de cristaux mixtes par spectroscopie infrarouge de réflexion : verres structuraux de type k(1##x)(nh#4)#xh#2po#4." Nancy 1, 1992. http://www.theses.fr/1992NAN10015.

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D'après notre étude des systèmes du type kadp-x, nous avons mis en évidence que ces cristaux se divisent en trois groupes: 1) 0,75<x1---> une transition de phase du type paraélectrique-antiferroélectrique; 2) 0,2<x<0,75---> le cristal ne subit pas de transition de phase (7 k); 3) 0x<0,2---> une transition de phase du type paraélectrique-ferroélectrique. Notre étude montre que le mode de translation polarisé suivant l'axe c dans les cristaux mixtes kadp-x, présente un comportement à deux modes. Nous avons développé un modèle de dynamique du réseau avec lequel nous démontrons que le second mode

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39

Weingärtner, Adrien. "The plasma membrane lipid asymmetry of Leishmania donovani and its relevance for phagocytosis." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16509.

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In großen Teilen der Welt verursachen intrazelluläre Parasiten der Spezies Leishmania schwerwiegende Infektionen beim Menschen. Die Exposition eines Phospholipids (Phosphatidylserin, PS) steht unter Verdacht Fresszellen zur Aufnahme der Parasiten zu stimulieren. Bisher ist die Regulation der Phospholipidverteilung in der Plasmamembran dieser Parasiten kaum erforscht. In der vorliegenden Arbeit wurde ein lipidtransportierender Proteinkomplex identifiziert, der einen wesentlichen Beitrag zur asymmetrischen Lipidverteilung in der Plasmamembran von Leishmania donovani leistet. Die Zerstörung des

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40

Oladunni, Fatai S. "MECHANISMS OF TYPE-I IFN INHIBITION: EQUINE HERPESVIRUS-1 ESCAPE FROM THE ANTIVIRAL EFFECT OF TYPE-1 INTERFERON RESPONSE IN HOST CELL." UKnowledge, 2019. https://uknowledge.uky.edu/gluck_etds/43.

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Equine herpesvirus-1 (EHV-1) is one of the most important and prevalent viral pathogens of horses causing a major threat to the equine industry throughout most of the world. EHV-1 primarily causes respiratory disease but viral spread to distant organs enables the development of more severe sequelae; abortion and neurologic disease. In order to produce disease, EHV-1 has to overcome the innate barrier of the type-I interferon (IFN) system in host cells. However, the underlying mechanisms employed by EHV-1 to circumvent the type-I IFN response in host cells are not well understood. In this proje

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41

Schmid, Roman. "Synthese, lokalanästhetische Wirkung und Konformationsanalyse einiger 2-substituierter 3,1-Benzoxazin-4-one und Chinazolin-4-one als Beitrag zur Frage der pharmakologisch aktiven Konformation /." [S.l.] : [s.n.], 1986. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=8106.

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42

Södersten, Fredrik. "Cartilage oligomeric matrix protein (COMP), thrombospondin-4 (TSP-4) and type I and III collagens in tendon : an immunohistochemical and biochemical study /." Uppsala : Dept. of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/200694.pdf.

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43

Forrer, Kurt. "Gleichgewichtsaufklärungen und mechanistische Studien an 2-Mercuri-4-nitrophenol-Komplexen /." [S.l.] : [s.n.], 1986. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=8032.

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44

Fässler, Lukas Emanuel. "Das 4-Schritte-Modell : Grundlage für ein kompetenzorientiertes E-Learning /." kostenfrei, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17521.

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45

Thirlwell, Sarah Wendy-Lee. "Analysis of the structure and function of adenovirus type 5 early region 4 protein." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0033/MQ64466.pdf.

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46

Jonson, Carl-Oscar. "The Importance of CTLA-4 and HLA Class II for Type 1 Diabetes Immunology." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1020s.pdf.

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47

Shah, Riyaz Nazeerul Haq. "The transcriptional mechanisms of fibroblast growth factor receptor type 4 overexpression in pancreatic carcinoma." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271806.

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48

Wang, Minchuan. "Localisation and function of type II α and β phosphatidylinositol 5-phosphate 4-kinases". Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611569.

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49

Jacob, Claire. "Régulation du stress oxydant par les phosphodiestérases de type 4 : implication des MAP kinases." Rennes 1, 2003. http://www.theses.fr/2003REN1B069.

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Nous avons montré : 1/ dans les neutrophiles de rat que les phosphodiestérases de type 4 (PDE4) inhibaient ERK1/2 par une interaction directe et que les inhibiteurs PDE4 inhibaient le production d'O2[Anion superoxyde] induite par le fMLP par une activation de ERK1/2 indépendante de l'AMPc. 2/ chez le patient atteint de bronchopneumopathie chronique obstructive (BPCO) que les inhibiteurs PDE4 étaient plus efficaces dans les cellules mononuclées que dans les neutrophiles pour inhiber la production d'O2 induite par le fMLP et que cette inhibition se faisait par une voie dépendante de l'AMPc et pa

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Al-Tamimi, Enas K. "Effect of resistant starch type 4 on glycemia and insulin sensitivity in young adults." Diss., Kansas State University, 2007. http://hdl.handle.net/2097/4220.

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Doctor of Philosophy<br>Department of Human Nutrition<br>Mark D. Haub<br>Objective: The objective was to compare the postprandial glycemic and insulinemic responses to nutrition bars containing either cross-linked RS type 4 (RS4[subscript]XL) or standard wheat starch in normoglycemic adults (n=13; age= 27±5 yr; BMI=25±3 kg/m²). Methods: Volunteers completed three trials during which they consumed a glucose beverage (GLU), a puffed wheat control bar (PWB), and a bar containing RS4[subscript]XL matched for available carbohydrate content. Serial blood samples were collected over two hours a

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