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1

Richardson, Lesley, and n/a. "The effectiveness of videotape support in enhancing print based learning material." University of Canberra. Education, 1989. http://erl.canberra.edu.au./public/adt-AUC20061107.124959.

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In higher education greater emphasis is being placed on independent study techniques for both on-campus and off-campus (distance education) students. At the University College of Southern Queensland the development of learning support material has been print based with other media included as supplementary material. The purpose of this study was to see if videotape support material had a mark benefit on the improvement of learning for students using print based study material as their basic learning resource. A Solomon Four-Group research design was used for this study. Subjects comprised all
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Neuenschwander, García-Calderón Martín. "Facultad de Arquitectura UCSP en Arequipa." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2013. http://hdl.handle.net/10757/273380.

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La UCSP es una comunidad académica privada, animada por las orientaciones de la vida de la Iglesia Católica administrada por el MVC; al adquirir la actual edificación para su campus universitario, tuvo que acondicionar un casco en abandono planificado originalmente para ser un hotel. La propuesta se basa en la ampliación de la Universidad Católica San Pablo UCSP en Arequipa, que consta de la nueva facultad de arquitectura (No existente en la curricula actual de la universidad) y de los servicios complementarios que carece la edificación existente, sobre terrenos colindantes a éste; respetando
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3

Cavanagh, Kate. "UCS expectancy biases and specific phobias." Thesis, University of Sussex, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300600.

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There is now considerable evidence that phobic responding is associated with a bias towards expecting aversive or traumatic outcomes following encounters with the phobic stimulus (e.g. Davey, 1995). In terms of conditioning contingencies, this can be described as a bias towards expecting an aversive or traumatic outcome (the unconditioned stimulus - UCS) following a phobic stimulus (the conditioned stimulus - CS). Research into the role of UCS expectancy biases in the development and maintenance of specific phobias has three basic requirements. First, it is not clear whether the ues expectancy
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Martwong, Ekkachai. "Design of surface-attached hydrogel thin films with LCST/UCST temperature-responsive properties." Thesis, Sorbonne université, 2018. http://www.theses.fr/2018SORUS120/document.

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Les films minces d'hydrogels thermosensibles à propriétés LCST/UCST (Lower/Upper Critical Solution Temperature) avec des températures de transition variables ont été mis au point pour des applications spécifiques. Les réseaux chimiques de polymères fixés de manière covalente sur des substrats solides plans ont été synthétisés par une approche polyvalente et facile à mettre en œuvre en utilisant la chimie click thiol-ène. Elle consiste à déposer des polymères préformés et réactifs en présence des réticulants dithiol sur des substrats modifiés thiol, la réaction de thiol-ène permettant la réticu
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Martins, Paula Cristina Garcia. "A análise do modelo organizativo dos Cuidados de Saúde Primários no ACeS de Oeiras." Master's thesis, Instituto Superior de Ciências Sociais e Políticas, 2013. http://hdl.handle.net/10400.5/6410.

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Tese de Mestrado em MPA-Administração Pública com especialização em Saúde<br>O início da reforma dos cuidados de saúde primários aconteceu em 2005, com o Programa do XVII Governo Constitucional, que tinha como objetivo “atribuir uma particular relevância à reestruturação dos centros de saúde, pela proximidade ao cidadão e pelo contributo que dão à melhoria dos níveis de vida dos Portugueses. ” (Decreto-Lei n.º 88, 2005, p. 3606) Em 2006, surgiram as Unidades de Saúde Familiar (USF) como o primeiro movimento da reforma. As USF são unidades funcionais com autonomia administrativa, técnica e fun
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6

Morés, Andréia. "Inovação e cursos de Pedagogia EAD : os casos UCS e UFRGS." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/39665.

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No presente estudo investigaram-se as inovações pedagógicas, científicas e tecnológicas presentes nos cursos de Pedagogia, na modalidade Educação a Distância (EaD) da Universidade de Caxias do Sul (UCS) e da Universidade Federal do Rio Grande do Sul (UFRGS). As universidades investigadas, uma comunitária e outra pública federal, têm larga experiência na formação de professores. No entanto, os cursos EaD em formação docente são experiências recentes. A metodologia incluiu o Estudo dos Casos embasado em Yin (2005). A coleta de dados para constituição da cada caso abarcou entrevistas semiestrutur
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Teitelbaum, Jennifer. "UCSF MOUNT ZION: The Closure of a Teaching Hospital and Its Primary Care Residency Program." Yale University, 2003. http://ymtdl.med.yale.edu/theses/available/etd-07012003-151744/.

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In November 1999, financial losses led the University of California at San Francisco Medical Center (UCSF) to close all inpatient services at Mount Zion Hospital, a community teaching hospital affiliated with UCSF since 1990. As a result of the closure, Mount Zions primary care residency program (MZPC) was merged with UCSFs university-based primary care program. We examined these events in the context of three major currents in U.S. health care: containment of rising health care costs, financial pressures on teaching hospitals, and the shifting priorities in graduate medical education with res
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8

Ozcelik, Ozgur. "A mechanics-based virtual model of NEES-UCSD shake table theoretical development and experimental validation /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3320217.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed September 22, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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9

Liu, Fangyao [Verfasser], and Franz Xaver [Akademischer Betreuer] Schmid. "Linear and Cross-linked UCST-Type Polymers : Synthesis and Properties / Fangyao Liu. Betreuer: Franz Xaver Schmid." Bayreuth : Universität Bayreuth, 2015. http://d-nb.info/1075807840/34.

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Nizardo, Noverra Mardhatillah [Verfasser], and André [Akademischer Betreuer] Laschewsky. "Thermoresponsive block copolymers with UCST-behavior aimed at biomedical environments / Noverra Mardhatillah Nizardo ; Betreuer: André Laschewsky." Potsdam : Universität Potsdam, 2018. http://d-nb.info/1218403659/34.

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Käfer, Florian [Verfasser], and Seema [Akademischer Betreuer] Agarwal. "New non-ionic polymers with UCST-type and complex phase transition behavior / Florian Käfer ; Betreuer: Seema Agarwal." Bayreuth : Universität Bayreuth, 2019. http://d-nb.info/1190170752/34.

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Sadio, Rute Sofia Madruga Pereira. "Autocuidado na diabetes mellitus tipo II e vulnerabilidade ao stress dos idosos de uma UCSP do Norte Alentejano." Master's thesis, Universidade de Évora, 2018. http://hdl.handle.net/10174/23572.

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Em Portugal 40,7% da população tem diabetes, estando relacionado com o aumento da taxa de envelhecimento da estrutura etária da população e sendo considerado um desafio de saúde pública. Por sua vez, os programas de combate à Diabetes incidem na prevenção primária ao nível do autocuidado e englobam nas intervenções a gestão de stress. Este relatório visa descrever todas as atividades desenvolvidas ao longo do estágio, em particular, o projeto de intervenção sobre o autocuidado na diabetes mellitus tipo 2 (nomea-damente alimentação e exercício físico) e a vulnerabilidade ao stress nos idosos da
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Harris, Richard Mark. "UCS - a novel gene family involved in calcium homeostasis and nutrition in Arabidopsis thaliana." Thesis, University of York, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437586.

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Lindström, Emil. "Windows Phone - Bokningsapp för taxiresor." Thesis, Linköpings universitet, Medie- och Informationsteknik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-108860.

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Användare kan idag boka taxi via TaxiCaller på webben, iPhone och Android. De vill även finnas på Windows Phone 8 och därmed stödja de tre största smartphoneplattformarna. Den här rapporten syftar till att undersöka hur en applikation kan utvecklas med hjälp av ett användarcentrerat arbetssätt för att uppnå hög användbarhet. Prototyping, card sort, användbarhetskrav är några av de metoder som tillämpats. Rapporten beskriver metoderna genom dess teori, hur de tillämpats i projektet samt dess resultat. Det grundläggande genomförandet var att samla in användarinformation för att sedan utveckla en
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Xerri, Eliana Gasparini. "Da Universidade da Serra ? Universidade de Caxias do Sul/RS (1955 2002): o pensar e o construir da universidade na serra ga?cha." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2012. http://tede2.pucrs.br/tede2/handle/tede/3712.

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Made available in DSpace on 2015-04-14T14:23:23Z (GMT). No. of bitstreams: 1 437555.pdf: 3403973 bytes, checksum: 6dc7d86a8fb80105f890913ff00b1eb4 (MD5) Previous issue date: 2012-01-20<br>This study analyzes the history of Universidade de Caxias do Sul, located at Rio Grande do Sul, between the years of 1950, decade of the creation of the first higher education classes on the city of Caxias do Sul, and 2002, end of the management characterized by the regionalization of the university. The history of the Universidade de Caxias do Sul associate at the higher education in the Brazil, here const
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Mu, Tianhong. "Soil Stabilization with Fly Ash and Fibers." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/theses/1301.

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In this study, coal combustion by-products mainly fly ash, commercial fibers and a natural fiber i.e., human hair were applied to stabilize the kaolinite clay and local Carbondale soil i.e., silty clay. During recent decades, the demand for infrastructures such as highways, buildings, bridges have greatly increased, especially in the areas where population was growing rapidly. All of these infrastructures need a stable foundation and in many cases the original land couldn't sustain the load from the infrastructures. In such situation, soil stabilization becomes an essential step before the fou
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Mantovani, Lucas Machado. "Estudo de tradução, adaptação e validação da versão brasileira da UCSD Performance-based Skills Assessment (UPSA) em pacientes com Esquizofrenia." Universidade Federal de Minas Gerais, 2015. http://hdl.handle.net/1843/BUBD-9WGQNP.

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Introduction: Schizophrenia is a serious mental illness, presenting with important functional deficits throughout lifetime. The UCSD Performance-based Skills Assessment (UPSA) is a measure of Functional Capacity and assesses skills involved in community tasks, commonly impaired in patients with Schizophrenia. It has good psychometric properties, and is currently the most studied, recommended and used Functional Capacity assessment around the world. A brief version (UPSA-B), encompassing only two of the five original subdomains, has also been developed and often employed in the last years. To o
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Pineda, Contreras Beatriz Amanda [Verfasser], and Seema [Akademischer Betreuer] Agarwal. "Basic Studies of UCST Polymers in Water and their Processing as Films and Fibers / Beatriz Amanda Pineda-Contreras ; Betreuer: Seema Agarwal." Bayreuth : Universität Bayreuth, 2017. http://d-nb.info/1136017496/34.

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Soldatelli, Volnei Flávio. "Avaliação da comunidade fitoplanctônica em lagoas de estabilização utilizadas no tratamento de efluentes domésticos : estudo de caso - ETE - UCS." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/10953.

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Este trabalho teve por objetivo relacionar a estrutura da comunidade fitoplanctônica com as variáveis físicas, físico-químicas e químicas das Lagoas de Maturação da Estação de Tratamento de Esgotos da Universidade de Caxias do Sul, no período de um ano. Foram considerados os atributos da comunidade (riqueza, composição, densidade, diversidade e eqüitabilidade), suas relações com as variáveis abióticas (temperatura do ar e da água, turbidez, transparência da água, pH, condutividade elétrica, OD, DBO5 total e solúvel, DQO total e solúvel, sólidos suspensos totais e voláteis, nitrato, nitrito, ni
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Mecca, Marlei Salete. "Desenvolvimento de um protótipo de EIS(executive information system) que possibilita a integração dos níveis hierárquicos : o caso UCS." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 1998. http://hdl.handle.net/10183/2166.

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Este trabalho tem o objetivo de desenvolver e avaliar um Protótipo de um EIS (Executive Information System) que integre os níveis hierárquicos operacional, tático e estratégico, a fim de suprir e dar suporte, quanto a informações, a uma das Pró- Reitorias da Universidade de Caxias do Sul - UCS. Quer-se demonstrar não só a importância mas também a contribuição da integração, através do acesso e compartilhamento das informações, dos níveis hierárquicos, proporcionada pelo Protótipo, para a obtenção da eficiência e eficácia das atividades desenvolvidas na Pró-Reitoria em estudo. Através de revisã
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Vuelma, Valquiria Paza. "O papel dos stricto sensu em administração da PUCRS e UCS, na formação de empreendedores : a visão dos alunos egressos." reponame:Repositório Institucional da UCS, 2010. https://repositorio.ucs.br/handle/11338/544.

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Os Stricto Sensu em Administração são regulamentados pela CAPES Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, a qual preconiza pela qualidade, para tanto se utiliza de avaliações trienais. Cada Programa cria sua própria linha de pesquisa; porém o foco ainda é a formação de docentes de qualidade, embora haja, principalmente, na UCS e PUCRS a busca pela formação de empreendedores. No intuito de verificar o papel dos cursos de mestrados em estudo na formação de empreendedores, esta dissertação buscou, a partir da análise de literatura sobre o tema, caracterizar as dimensões do em
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Lindholm, Tobias. "Hållfasthetsundersökning av pastafyll i Zinkgruvan." Thesis, Luleå tekniska universitet, Institutionen för samhällsbyggnad och naturresurser, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-65504.

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The current mining method in Zinkgruvan today is underhand stoping. With this method the ore is mined downwards in disks. When the ore is extracted the stope is backfilled with paste which contains tailings, cement and water. The paste will constitute the ceiling in lower levels and are therefore vital for the safety and the requirements of the strength. The goal of this thesis is to increase knowledge about the paste’s strength after the usual tests within 28 days. Test objects are taken from two different paste’s in Burkland and Nygruvan and compares with old data from the same sights. Besid
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Sengor, Mahmut Yavuz. "The Deformation Characteristics Of Deep Mixed Columns In Soft Clayey Soils: A Model Study." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613075/index.pdf.

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Deep Mixing involves the introduction of cementitious or specially formulated solutions directly into the ground through the use of purpose built blending injection augers. The system is mainly designed to increase strength and reduce compressibility of treated soil. In the first stage of the research effective mixture ratios and mixture types of stabilizing agents were investigated for soft clays (CL form Eymir lake and kaolinite) by means of unconfined compression (UC) tests on stabilized soils. The unconfined compressive strength (UCS) values were obtained for 7,28,90 and 365 days of curing
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Andreis, Fernando. "Anteprojeto de infraestrutura verde e reconfiguração paisagística da área dos lagos do zoológico no Campus da Universidade de Caxias do Sul -UCS." reponame:Repositório Institucional da UCS, 2018. https://repositorio.ucs.br/11338/3839.

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A perda de benefícios ecológicos causada com o crescimento das cidades pode ser amenizada com o uso de tecnologias alternativas de infraestrutura e reinserção devegetação nativa em espaços urbanizados. Neste contexto, este trabalho busca realizar um anteprojeto de reconfiguração paisagística contemplando a reinserção de espécies vegetais nativas e implantação de tipologias de infraestrutura verde, ambos com a função de amenizar o impacto da urbanização e auxiliar o equilíbrio ambiental e harmonização paisagística do espaço. A área definida para o projeto encontra-se no campus da Universidade d
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Brun, Geoffrey. "Formulation de capsules à cœur aqueux pour la délivrance stimulable de protéines." Thesis, Paris 6, 2015. http://www.theses.fr/2015PA066487/document.

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Les gradients de concentration de peptides ou de protéines, ou leur relargage localisé, jouent un rôle primordial dans les voies de communication inter-cellulaire. L'activation locale de cellules est étudiée in vitro à l'aide de sources artificielles contraignantes ou invasives de protéines (pipettes, dispositifs microfluidiques). Des méthodes plus douces et moins invasives sont très demandées. À cet effet, nous avons développé deux types de capsules capables de libérer des macromolécules sous l'effet d'une stimulation extérieure. Le premier système emploie des liposomes additionnés d'un amphi
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Mineer, Samuel Thomas. "Roadway Safety Analysis Methodology." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6056.

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The Utah Department of Transportation (UDOT) Traffic and Safety Division continues to advance the safety of the state roadway network through network screening and decision making tools. In an effort to aid UDOT in meeting this goal, the Department of Civil and Environmental Engineering at Brigham Young University (BYU) has worked with the Statistics Department in developing analysis tools for highway safety, specifically the Utah Crash Prediction Model (UCPM) and the Utah Crash Severity Model (UCSM). Additional tools and methodologies, such as the "Hot Spot Identification and Analysis," have
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Bilou, Liliana Maria Cebola. "A prevenção do risco de pé diabético em adultos." Master's thesis, Universidade de Évora, 2013. http://hdl.handle.net/10174/10831.

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O presente relatório tem como objectivo apresentar os resultados obtidos na aplicação de um Projecto de Intervenção Comunitária. A área temática foi a Prevenção de Complicações no Pé Diabético em utentes adultos com Diabetes Mellitus tipo 2 tendo como objectivos: Promover a acessibilidade à consulta de vigilância de enfermagem e consulta de vigilância médica e aumentar os conhecimentos sobre a diabetes e prevenção de complicações tardias. A população-alvo seleccionada foi constituída por 22 utentes inscritos na UCSP de Montemor-o-Novo. Foi realizado o diagnóstico de situação, utilizando a apli
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Melo, Fl?via Luana Souza de. "?tica na pesquisa em turismo: percep??es de discentes de programas de p?s-gradua??o stricto sensu em turismo UFRN, UCS e UNIVALI." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/18159.

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Made available in DSpace on 2014-12-17T15:51:32Z (GMT). No. of bitstreams: 1 FlaviaLSM_DISSERT.pdf: 1575036 bytes, checksum: bd9a6689fff5ecc9afddc0317d8fc5d8 (MD5) Previous issue date: 2012-08-24<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>This study analyzed the perception of ethics on the part of students of Post-graduation in Tourism, to develop their academic research. It is characterized as exploratory-descriptive, being considered quantitative with some elements analyzed qualitatively. Data were collected through an electronic questionnaire, originated in google
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McFaddin, Jared Douglas. "Development of Correlations for Unconfined Compression Strength and Methods of Field Preparations and Preservation of Kope Shale." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1217259954.

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Rabinovici, Andréa. "As terras de todos e seus donos: desdobramentos possíveis das articulações e parcerias entre sociedade civil, organizações não governamentais (ONGs) e unidades de conservação (UCs)." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/90/90131/tde-16052007-175624/.

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O presente trabalho é fruto de uma pesquisa bibliográfica na qual as formas de conservação da natureza são questionadas. Diversas alternativas de manejo dos recursos naturais com a participação comunitária são apontadas principalmente através da formatação de parcerias junto à sociedade civil organizada na forma de Organizações Não –Governamentais representativas. Buscou-se exemplos concretos de Unidades de Conservação brasileiras, no caso Amazônicas, onde, de diferentes formas, as parcerias e o manejo participativo têm sido implementados com relativo sucesso para se repensar, entre outros, a
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Soto, Leiva Camila. "Modelamiento de unidades de lito-geotécnicas, proyecto Caracoles." Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/130472.

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Geóloga<br>Éste estudio se desarrolló a partir de la necesidad de caracterizar el macizo rocoso del proyecto Caracoles, yacimiento tipo pórfido cuprífero, el cual se ubica en el distrito Centinela perteneciente a la comuna de Sierra Gorda en la región de Antofagasta. El objetivo de ésta investigación se basó en la elaboración de un modelo de unidades lito-geotécnicas del proyecto, mediante datos geotécnicos y geológicos. Para realizar la confección descrita anteriormente se efectuaron las siguientes tareas: Estándares de mapeo geotécnico, compilación de la información en una base de datos, v
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Ding, Xiaobin. "Development of a Rock Expert System (RES) for Evaluating Rock Property Values and Utilization of Three Dimensional Particle Flow Code (PFC3D) to Investigate Rock Behavior." Diss., The University of Arizona, 2013. http://hdl.handle.net/10150/293428.

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This research consists of two main parts: development of a rock expert system (RES) as an easy-to-use and effective tool for evaluating rock properties, and modification and utilization of the three-dimensional Particle Flow Code (PFC3D) to analyze rock behavior. Because of different reasons, it is often difficult to obtain the rock property values directly. As an alternative, typical values and empirical correlations are often used to evaluate the rock property values. However, the typical values and empirical correlations come in various forms and are scattered in different sources. It is of
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Ali, Ghada Abdulbaqi. "Temperature Dependency of the Rheological Properties and Strength of Cemented Paste Backfill That Contains Sodium Silicate." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/41985.

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Over the past decades, cemented paste backfill (CPB) has become a common, environmentally friendly method of managing mine wastes (such as tailings). This technology allows up to 60% of the total amount of tailings to be reused and filled in the mine stopes after converting them into cemented material. Beside reducing the environmental risks associated with the traditional disposal of these materials, turning them into cemented material and placing them in the underground mine stopes can also provide secondary support for these stopes in addition to minimizing the risk of ground subsidence in
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Smit, Andre. "Development of a telerobotic test bench system for small-field-of-operation bilateral applications with 3D visual and haptic (kinaesthetic) feedback." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86516.

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Thesis (MScEng) Stellenbosch University, 2014<br>ENGLISH ABSTRACT: Teleoperation as a field has seen much change since its inception in the early 1940s with Dr. Raymond Goertz producing the first teleoperation system for manipulating radioactive materials. With advances in core and supporting technologies, the systems have grown in complexity and capability, allowing users to perform tasks anywhere in the world irrespective of physical distance. The feasibility of such systems has increased as the drive for use of telepresence robots, exploration robots as in space exploration, search an
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Zhang, Hu. "Étude de nouveaux polymères thermosensibles en solution aqueuse et de leur changement de solubilité induit par le pH." Thèse, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/8740.

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Résumé: Les polymères stimuli-répondants sont capables de changer leurs propriétés ou structures de façon importante en réagissant à un signal de stimulation. Parmi ceux-ci, des polymères sensibles à une variation de température ont fait l'objet de beaucoup de recherches et de développement, parce qu’un changement de température est un stimulus facile à appliquer, et que des fluctuations de température spontanées se produisent dans le milieu biologique. En plus, des polymères thermosensibles peuvent également répondre à d'autres stimuli tels que la lumière, le pH ou un champ magnétique. Ces po
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Duraes, Fernanda do Valle. "O papel dos receptores do tipo Toll (TLRs) na infecção pelo Schistosoma mansoni." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/UCSD-85EQ3N.

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ABSTRACTSchistosomiais is a chronic helminthic infection and remains as an important morbidity factor in tropical endemic areas such as Brazil. Toll-like receptors (TLRs) play an important role in the innate recognition of pathogens by Dendritic cells (DCs) and in the induction of immune responses. Although it is clear that TLR2, TLR3 and TLR4 can recognize different Schistosoma components in vitro, little is known regarding the role of these receptors in vivo. To characterize the innate immune response during Schistosoma infection, WT (C57BL/6) and MyD88-, TLR2- and TLR4 deficient mice were i
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37

Goes, Vinicius de Souza. "Expressão da Rho1 GTPase de Schistosoma mansoni em células dentríficas murinas." Universidade Federal de Minas Gerais, 2004. http://hdl.handle.net/1843/UCSD-8H8KAD.

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As células dendríticas possuem um papel determinante na indução de resposta imune primária. Estudos recentes tem demonstrado o papel importante destas células na indução de imunidade específica a doenças parasitárias, dente elas a esquistossomose. Este fato despertou grande interesse do nosso grupo na manipulação de células dendríticas para desenvolver uma vacina celular que tem como objetivo induzir imunidade protetora contra o Schistosoma mansoni. Células dendríticas viáveis foram obtidas a partir do cultivo de precursores da medula óssea murina na presença das citocinas GM-CSF e IL-4. Em mé
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38

Campos, Danilo Roman. "Alterações eletromecânicas do miócito cardíaco na fase aguda da doença de Chagas em modelo murino: papel do óxido nítrico, intereferon-gama e ânion superóxido." Universidade Federal de Minas Gerais, 2011. http://hdl.handle.net/1843/UCSD-8H5PGK.

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Cardiomyopathy observed during infection by the flagellated protozoan Trypanosoma cruzi has unknown mechanism concerning your genesis. Chagas disease is separated in two distinct phases, acute and chronic. In the acute phase it is observed a large number of parasites on blood stream, following activation of immune system which induces severe miocarditis. These alterations in many cases could lead to occurrence of severe arrhythmias, leading to death. Despite of the great importance of Chagas disease in the Latin American, few is known about the mechanisms involved in the establishment of this
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Araujo, Patricia Rosa de. "Elementos regulatórios responsáveis pelo controle da estabilidade do mRNA de alfa tubulina de Trypanosoma cruzi." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/UCSD-87RPMG.

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alpha/beta-tubulin mRNAs expression in T.cruzi is under an auto-regulatory control that affects these transcript half-lives during the parasite life cycle. Whereas epimastigotes present high levels of tubulin mRNAs, an excess of free tubulin monomers is correlated to a decrease in tubulin mRNA levels in amastigotes. This reduction is not a result of changes in transcription; instead, it is due to a reduction in and tubulin mRNA half-lives. By incubating epimastigotes with vinblastine (a microtubule depolymerization inducer) we have observed an inverse correlation between free tubulin and mRNA
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40

Freitas, Jorge Marcelo de. "Aspectos genéticos de parasitos e hospedeiros envolvidos na patogênese da doença de chagas." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/UCSD-854JXQ.

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Chagas disease, which is caused by Trypanosoma cruzi, afflicts more than 18 million people in the American continent. Both a complex populational structure and a extensive intraespecific variability are observed in this parasite, but a great number of genetic andbiochemical markers support the taxon subdivision into at least two major lineages: T. cruzi I - associated to the wild transmission cycles; and the T. cruzi II - associated to the domestic transmission cycles. The human disease shows variable presentation in the chronic phase, withlow parasitism levels and undeterminable clinical rout
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41

Rodrigues, Claudiney Melquiades. "Análise multifatorial de mecanismos patogenéticos implicados na infecção por Trypanosoma cruzi em camundongos BALB/c." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/UCSD-8H8MEN.

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A century after the discovery of the Trypanosoma cruzi, many uncertainties remain with respect to factors determining the pathogenesis of Chagas disease. In the present work, the effects of the association of two T. cruzi populations with opposite virulence and pathogenicity in BALB/c mice were investigated through of the simultaneous analyses of multiple biological parameters during the acute phase of infection. For this, the animals were infected with 100 trypomastigotes of JG or CL Brener or coinfected with 50 trypomastigotes of each one of the respective T. cruzi populations by i.p. route.
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42

Ireno, Ivanildce Cristiane. "Peptidoma parcial do veneno do escorpiao da amazonia Brotheas amazonicus." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/UCSD-84KL7J.

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Brotheas amazonicus is an endemic scorpion from the northern Brazil. Since it dwells the Amazon forest, human accidents involving this species occur sporadically. In this study, two-dimensional liquid chromatography (2D-LC), MALDI-TOF-TOF, de novo sequencing and similarities searches were employed in assessment of the peptide diversity of the Brotheas amazonicus venom. The chromatographic profiles and the mass compositions of the venom are provided. A total of 201 molecules were detected with molecular masses between 800 and 17000 Da. Eight peptides were de novo sequenced which did not present
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43

Cortes, Denise Fonseca. "Infecções com baixas doses de Leishmania amazonensis: um modelo para o estudo de leishmania tegumentar americana." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/UCSD-8HENY7.

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A model of infection with Leishmania amazonensis in the skin, with low doses of parasites, was compared to infection with high doses of L. amazonensis and low and high doses of L. major. C57BL/6 mice were infected with 103 or 106 parasites in the ear and the outcome of infection was assessed. The appearance of lesions in mice infected with 103 parasites was delayed compared to mice infected with 106 Leishmania and parasites were detectable at the infection site even before lesions were. Mice infected with L. amazonensis displayed persistent lesions, while infection with L. major spontaneously
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Silva, Danielle Marra de Freitas. "Restrição maternal de tiamina afeta aspectos cognitivos espaciais e níveis cerebrais de GABA e glutamato da prole, avaliados em fases posteriores do desenvolvimento." Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/UCSD-8HEK9E.

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Thiamine (vitamin B1) deficiency causes lesions in different brain regions and may affect glutamatergic and GABAergic circuits of the central nervous system, which are related to a range of behavioral aspects. Several studies on cognitive and biochemical changes in adult rats subjected to thiamine deficiency have been published; however, few studies address this issue using animals that underwent deficiency during the early stages of development. Thus, in the present study, we evaluated the effects of thiamine restriction during lactation (Part I) or peri-natal period (Part II) on spatial cogn
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Silva, Carolina Furtado Torres da. "Reparo de DNA em dois patógenos humanos: caracterização do gene IMP4 de Schistosoma mansini e estudos acerca do MMR, Sistema GO e taxa de mutação em Trypanosoma cruzi." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/UCSD-8FVPH6.

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Cells have evolved a complex set of mechanisms to appropriately respond to genotoxic damage, ensuring genomic stability. Such responses retain mutation rates in an acceptable level, through a fine-tuning balance between genome maintenance and generation of genetic variability. In this work, we studied some features of the DNA repair machinery of Schistosoma mansoni and Trypanosoma cruzi, the causative agents of schistosomiasis and Chagas disease in Brazil. Both parasites need to adapt to distinct environments, and are consequently exposed to various DNA damaging agents. Using a functional hete
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Campos, Danilo Roman. "Disfunção cardíaca em animal nocaute para o receptor do tipo 2 para bradicinina." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/UCSD-8H5QQF.

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The Kinins are important peptides concerning control of cardiovascular function. Their action mechanism depend on the activation of two distinct receptor, type 1 and 2 bradykinin receptor (B1R and B2R). They both are coupled to G protein, which are responsible to activate different intracellular pathways, involved in different cellular process. Their role in the control of heart function is not well understood. Based on this issue, we decided to evaluate the heart physiology of mouse knockout to type 2 receptor of bradykinin (B2R-/-), in order to evaluate the B2R function in the heart physiolo
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Freitas, Renata Nascimento de. "Estudos moleculares de tecidos normais e tumores malignos de roedores tratados com samambaia (Pteridium aquilinum)." Universidade Federal de Minas Gerais, 2001. http://hdl.handle.net/1843/UCSD-8HEPNW.

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Bracken fern (Pteridium aquilinum) toxicity and carcinogenicity properties have been extensively described in domestic and experimental animals. Some epidemiologic studies have associated the human exposition to the bracken fern and /or to its toxins with a higher risk for the occurrence of esophagus cancer in Venezuela and stomach cancer in Japan, Brazil, Costa Rica, United Kingdom ad Venezuela. However, these epidemiologic studies are not enough to unequivocally establish a causal relationship between bracken fern and cancer development in human beings. In the present work we proposed to inv
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48

Correa, Natassia Caroline Resende. "Clonagem e expressão de protease mitogênica de Carica candamarcensis." Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/UCSD-8H6P5G.

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Cysteine proteinases are found in many organisms and play essential functions in parasites, mammals and plants. Carica candamarcensis, a member of the Caricaceae family, contains highly active cysteine proteinases in its latex. One of the proteins isolated from this specie was named CMS2MS2, it contains 214 aminoacids, exhibits proteolytic activity and shows mitogenic effect on mammal cells. The objective of this study was to produce recombinant CMS2MS2 to further study the biological activity and structure characterize this enzyme. To clone this gene a degenerate primer pair was derived from
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Breyner, Natalia Martins. "Condrogênese de células tronco mesenquimais derivadas de Rattus Norvegicus utilizando matriz orgãnica tridimensional à base de quitosana." Universidade Federal de Minas Gerais, 2006. http://hdl.handle.net/1843/UCSD-8H8PVV.

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Cartilage is known to be an avascular tissue and this characteristic taken together with others provides the tissue a very limited regeneration capacity. Consequently, a small damage to the tissue results in progressive damages or degenerative processes like osteoarthrite. Tissue engineering techniques has been applied not only in the treatment of cartilage damage but also in other medical fields such as orthopedic and odontology. In the present work, it was demonstrated that the 3D (tridimesional) chitosan scaffold was efficient in the adhesion and differentiation process of the MSCs (Mesench
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50

Caetano, Braulia Costa. "Desenvolvimento de um modelo de vacinação contra Toxoplasma gondii empregando adenovírus recombinante." Universidade Federal de Minas Gerais, 2005. http://hdl.handle.net/1843/UCSD-87RNXA.

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In the present study, genes encoding the SAG1, SAG2 and SAG3 proteins of T. gondii were cloned into replication-deficient recombinant adenoviruses, after being modified for appropriate expression in mammalian cells. Modifications included removal of 3-end sequences encoding the GPI-anchoring motifs and, for SAG3, substitution of the 5´-end encoding the natural signal sequence for the influenza virus haemaglutinin signal sequence (HASS). After the characterization of the three recombinant adenoviruses and demonstration of in vitro expression of the SAG proteins, the viruses were employed in imm
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