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Journal articles on the topic 'Ugi type reactions'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Nazeri, Mohammad Taghi, Hassan Farhid, Reza Mohammadian, and Ahmad Shaabani. "Cyclic Imines in Ugi and Ugi-Type Reactions." ACS Combinatorial Science 22, no. 8 (2020): 361–400. http://dx.doi.org/10.1021/acscombsci.0c00046.

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2

Murlykina, Maryna V., Oleksandr V. Kolomiets, Maryna M. Kornet, et al. "Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction." Beilstein Journal of Organic Chemistry 15 (June 12, 2019): 1281–88. http://dx.doi.org/10.3762/bjoc.15.126.

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Substituted 1H-pyrazolo[3,4-b]pyridine-4- and 1H-pyrazolo[3,4-b]pyridine-6-carboxamides have been synthetized through a Doebner–Ugi multicomponent reaction sequence in a convergent and versatile manner using diversity generation strategies: combination of two multicomponent reactions and conditions-based divergence strategy. The target products contain as pharmacophores pyrazolopyridine and peptidomimetic moieties with four points of diversity introduced from readily available starting materials including scaffold diversity. A small focused compound library of 23 Ugi products was created and s

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3

Neo, Ana G., and Carlos F. Marcos. "Pyrrolidinodiones in Enol-Ugi, Enol-Passerini, and Anomalous Enol-Passerini Condensations." Proceedings 9, no. 1 (2018): 6. http://dx.doi.org/10.3390/ecsoc-22-05864.

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In continuation of our recent research on the development of novel multicomponent reactions with isocyanides, we have used, for the first time, enols as the acid components in Ugi- and Passerini-type reactions. Thus, electron-poor pyrrolidinodiones react with aldehydes, amines, and isocyanides to give the enaminic four-component adducts. Conversely, in the absence of the amine component, careful control of the reaction conditions allows the involvement of one or two molecules of isocyanide to afford, selectively, either Passerini-type or pseudo-enol-Ugi-type products. These unprecedented conde

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4

Kaluđerović, Goran N., Muhammad Abbas, Hans Christian Kautz, et al. "Methionine and seleno-methionine type peptide and peptoid building blocks synthesized by five-component five-center reactions." Chemical Communications 53, no. 26 (2017): 3777–80. http://dx.doi.org/10.1039/c7cc00399d.

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5

Guerrero, Itziar, Marcos San Segundo, and Arkaitz Correa. "Iron-catalyzed C(sp3)–H functionalization ofN,N-dimethylanilines with isocyanides." Chemical Communications 54, no. 13 (2018): 1627–30. http://dx.doi.org/10.1039/c7cc09872c.

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6

Mao, Zhuo-Ya, Xiao-Di Nie, Yi-Man Feng, Chang-Mei Si, Bang-Guo Wei, and Guo-Qiang Lin. "Cu(OTf)2 catalyzed Ugi-type reaction of N,O-acetals with isocyanides for the synthesis of pyrrolidinyl and piperidinyl 2-carboxamides." Chemical Communications 57, no. 73 (2021): 9248–51. http://dx.doi.org/10.1039/d1cc03113a.

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7

Zarezin, Danil P., Olga I. Shmatova та Valentine G. Nenajdenko. "Chiral β3-isocyanopropionates for multicomponent synthesis of peptides and depsipeptides containing a β-amino acid fragment". Organic & Biomolecular Chemistry 16, № 33 (2018): 5987–98. http://dx.doi.org/10.1039/c8ob01507d.

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Chiral β<sub>3</sub>-isocyanopropionic acids derivatives is a new type of isocyanides for multicomponent reactions. The use of these isocyanides in Ugi and Passerini reactions allows to prepare short peptides and depsipeptides with β-amino acid moiety in the structure.

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8

Ruijter, Eelco, Romano Orru, Verónica Estévez, Laura Kloeters, Natalia Kwietniewska, and Esther Vicente-García. "Ugi-Type Reactions of Spirocyclic Indolenines as a Platform for Compound Library Generation." Synlett 28, no. 03 (2016): 376–80. http://dx.doi.org/10.1055/s-0036-1588084.

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9

Li, Dengke, Xianfu Shen, and Jian Lei. "Metal-Free Iodine/TEMPO-Mediated Aerobic Oxidative Ugi-Type Multicomponent Reactions with Tertiary Amines." Journal of Organic Chemistry 85, no. 4 (2019): 2466–75. http://dx.doi.org/10.1021/acs.joc.9b03168.

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10

Tanaka, Yusuke, Kousuke Hidaka, Tomoaki Hasui, and Michinori Suginome. "B(OMe)3as a Nonacidic Iminium Ion Generator in Mannich- and Ugi-Type Reactions." European Journal of Organic Chemistry 2009, no. 8 (2009): 1148–51. http://dx.doi.org/10.1002/ejoc.200801190.

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11

Ostaszewski, R., D. E. Portlock, Anna Fryszkowska, and Katarzyna Jeziorska. "Combination of enzymatic procedures with multicomponent condensations." Pure and Applied Chemistry 75, no. 2-3 (2003): 413–19. http://dx.doi.org/10.1351/pac200375020413.

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A new synthetic method based on combination of enzymatic desymmetrization of 3-phenylglutaric anhydrides with multicomponent condensation is outlined. Enzymatic monoesterification of glutaric anhydrides was performed, and the derived monoacids were used as substrates for subsequent Ugi and Passerini multicomponent condensations. Both reactions were combined as two-step, one-pot processes. The choice of solvent and enzyme type has an appreciable effect on the course of reactions.

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12

Borah, Preetismita, Biswa Mohan Sahoo, Vhatkar Dattatraya Shivling, and Bimal Krishna Banik. "Microwave-Induced Ugi-Four Component Reactions: Synthesis of New Hetero- Steroid-Amino Acid Conjugates." Current Organic Synthesis 17, no. 8 (2020): 641–47. http://dx.doi.org/10.2174/1570179417666200825164654.

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Background: Aza-steroids are an important class of compounds because of their numerous biological activities. The hetero steroids have different hydrogen bonding ability and hydrophobicity in comparison to steroids. Materials and Methods: Microwave-induced synthesis of a novel type of hybrid hetero-steroid amine conjugates, following Ugi-four component reactions of steroidal amines with alanine and valine methyl esters as amino acid residues is described. Specifically, hetero-steroid-amino acid conjugate based on D-ring fused hetero steroidal amine, hetero-steroid-amino acid conjugate based on

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13

Song, Gui-Ting, Zhi-Gang Xu, Dian-Yong Tang, et al. "Facile microwave-assisted synthesis of benzimidazole scaffolds via Ugi-type three-component condensation (3CC) reactions." Molecular Diversity 20, no. 2 (2015): 575–80. http://dx.doi.org/10.1007/s11030-015-9646-7.

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14

Villanueva-Kasis, Oscar, Denisse A. de Loera, Sandra L. Castañón-Alonso та ін. "Efficient Synthesis of New α-β-Unsaturated Alkyl-Ester Peptide-Linked Chiral Amines". Proceedings 9, № 1 (2018): 34. http://dx.doi.org/10.3390/ecsoc-22-05769.

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Four new α-β-unsaturated alkyl-ester chiral amines were synthesized in excellent yields (77–95%) via peptide couplings from their corresponding α-β-unsaturated alkyl-ester anilines and N-Boc protected chiral aminoacids. To our delight, these polyfunctionalized compounds are being used as starting reagents in Ugi-type three-component reactions (Ugi-3CR) together with alkyl- and aryl-aldehydes and a chain-ring tautomerizable amino acid-containing isocyanide to synthesize novel oxazole-based macrocycle precursors. Thus, the aim of this communication is to show our most recent results of the synth

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15

Ngouansavanh, Tifelle, and Jieping Zhu. "IBX-Mediated Oxidative Ugi-Type Multicomponent Reactions: Application to the N and C1 Functionalization of Tetrahydroisoquinoline." Angewandte Chemie 119, no. 30 (2007): 5877–80. http://dx.doi.org/10.1002/ange.200701603.

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16

Ngouansavanh, Tifelle, and Jieping Zhu. "IBX-Mediated Oxidative Ugi-Type Multicomponent Reactions: Application to the N and C1 Functionalization of Tetrahydroisoquinoline." Angewandte Chemie International Edition 46, no. 30 (2007): 5775–78. http://dx.doi.org/10.1002/anie.200701603.

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17

Jiang, Gaoxi, Jian Chen, Jie-Sheng Huang, and Chi-Ming Che. "Highly Efficient Oxidation of Amines to Imines by Singlet Oxygen and Its Application in Ugi-Type Reactions." Organic Letters 11, no. 20 (2009): 4568–71. http://dx.doi.org/10.1021/ol9018166.

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18

Cioc, Răzvan C., Hans D. Preschel, Gydo van der Heijden, Eelco Ruijter, and Romano V. A. Orru. "Trityl Isocyanide as a Mechanistic Probe in Multicomponent Chemistry: Walking the Line between Ugi- and Strecker-type Reactions." Chemistry - A European Journal 22, no. 23 (2016): 7837–42. http://dx.doi.org/10.1002/chem.201600285.

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19

Xie, Chunsong, and Laihong Han. "Development of aqueous oxidative Ugi-type reactions by copper-catalyzed surfactant-promoted C(sp3)–H direct functionalization in water." Tetrahedron Letters 55, no. 1 (2014): 240–43. http://dx.doi.org/10.1016/j.tetlet.2013.11.006.

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20

de Graaff, C., L. Bensch, Matthijs J. van Lint, E. Ruijter, and R. V. A. Orru. "IBX-mediated oxidation of unactivated cyclic amines: application in highly diastereoselective oxidative Ugi-type and aza-Friedel–Crafts reactions." Organic & Biomolecular Chemistry 13, no. 40 (2015): 10108–12. http://dx.doi.org/10.1039/c5ob01519g.

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21

Jiang, Gaoxi, Jian Chen, Jie-Sheng Huang, and Chi-Ming Che. "ChemInform Abstract: Highly Efficient Oxidation of Amines to Imines by Singlet Oxygen and Its Application in Ugi-Type Reactions." ChemInform 41, no. 11 (2010): no. http://dx.doi.org/10.1002/chin.201011152.

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22

Xie, Chunsong, and Laihong Han. "ChemInform Abstract: Development of Aqueous Oxidative Ugi-Type Reactions by Copper-Catalyzed Surfactant-Promoted C(sp3)-H Direct Functionalization in Water." ChemInform 45, no. 20 (2014): no. http://dx.doi.org/10.1002/chin.201420046.

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23

de Graaff, C., L. Bensch, Matthijs J. van Lint, E. Ruijter, and R. V. A. Orru. "ChemInform Abstract: IBX-Mediated Oxidation of Unactivated Cyclic Amines: Application in Highly Diastereoselective Oxidative Ugi-Type and Aza-Friedel-Crafts Reactions." ChemInform 47, no. 7 (2016): no. http://dx.doi.org/10.1002/chin.201607039.

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24

Masdeu, Carme, Elena Gómez, Nana Aba Williams, and Rodolfo Lavilla. "Hydro-, Halo- and Seleno-Carbamoylation of Cyclic Enol Ethers and Dihydropyridines: New Mechanistic Pathways for Passerini- and Ugi-type Multicomponent Reactions." QSAR & Combinatorial Science 25, no. 5-6 (2006): 465–73. http://dx.doi.org/10.1002/qsar.200540193.

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25

Rostamnia, Sadegh, and Maryam Jafari. "Metal-organic framework of amine-MIL-53(Al) as active and reusable liquid-phase reaction inductor for multicomponent condensation of Ugi-type reactions." Applied Organometallic Chemistry 31, no. 4 (2016): e3584. http://dx.doi.org/10.1002/aoc.3584.

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26

Zheng, Jian-Feng, Xiang-Yang Qian, and Pei-Qiang Huang. "Direct transformation of amides: a one-pot reductive Ugi-type three-component reaction of secondary amides." Organic Chemistry Frontiers 2, no. 8 (2015): 927–35. http://dx.doi.org/10.1039/c5qo00146c.

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An efficient reductive Ugi-type reaction employing common secondary amides as starting materials has been established. The reaction exhibited a broad substrate scope, good chemoselectivity and functional group tolerance.

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27

Yao, Tuanli, Bo Wang, Beige Ren, Xiangyang Qin, and Tao Li. "Palladium-catalyzed Ugi-type reaction of 2-iodoanilines with isocyanides and carboxylic acids affording N-acyl anthranilamides." Chemical Communications 57, no. 35 (2021): 4247–50. http://dx.doi.org/10.1039/d1cc01226f.

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The first palladium-catalyzed Ugi-type multicomponent reaction for the synthesis of structurally diverse N-acyl anthranilamides from isocyanides, 2-iodoanilines and carboxylic acids has been developed.

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28

Liu, Yun-Lin, Xiang-Yu Mao, Xiao-Tong Lin, and Guo-Shu Chen. "A Zn(OTf)2 catalyzed Ugi-type reaction of 3-(2-isocyanoethyl)indoles with indole-derived ketimines: rapid access to hexacyclic spiroindolines." Organic Chemistry Frontiers 5, no. 15 (2018): 2303–7. http://dx.doi.org/10.1039/c8qo00382c.

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A Zn(OTf)<sub>2</sub> catalyzed Ugi-type reaction of 3-(2-isocyanoethyl)indoles and indole-derived ketimines was developed for the synthesis of hexacyclic spiroindolines featuring three stereocenters including two quaternary stereocenters.

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29

Mijangos, Marco V., and Luis D. Miranda. "Multicomponent access to indolo[3,3a-c]isoquinolin-3,6-diones: formal synthesis of (±)-plicamine." Organic & Biomolecular Chemistry 14, no. 15 (2016): 3677–80. http://dx.doi.org/10.1039/c6ob00231e.

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The complete tetracyclic core structure of plicamine, a novel Amaryllidaceae-type alkaloid, was expeditously prepared by an Ugi four-component condensation reaction, followed by a one-pot sequential phenolic oxidation and intramolecular coupling process.

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30

Guchhait, Sankar K., and Vikas Chaudhary. "Desilylative activation of TMSCN in chemoselective Strecker–Ugi type reaction: functional fused imidazoles as building blocks as an entry route to annulated purines." Org. Biomol. Chem. 12, no. 34 (2014): 6694–705. http://dx.doi.org/10.1039/c4ob00882k.

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Nucleophilic activation of TMSCN as an isocyanide equivalent by DABCO–THF in the Strecker–Ugi reaction facilitates the synthesis of functional imidazoles which, as building blocks, afford access to C8–N9 annulated purines.

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31

Saha, Debasmita, Preeti Wadhwa, and Anuj Sharma. "A sequential synthetic strategy towards unexplored dibenzo[b,f][1,4]thiazepine carboxamides: copper catalysed C–S cyclisation followed by Ugi type 3CC cascade." RSC Advances 5, no. 42 (2015): 33067–76. http://dx.doi.org/10.1039/c5ra04175a.

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A two-step diversity oriented synthetic protocol has been developed to access a novel class of dihydrodibenzo[b,f][1,4]thiazepine-11-carboxamides via copper-mediated cyclisation followed by Ugi- Joullié reaction sequence.

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32

Shaabani, Ahmad, Zeinab Hezarkhani, and Elham Badali. "One-pot oxidative Ugi-type three-component reaction of aromatic hydrocarbons of petroleum naphtha: comparing catalytic effect of cellulose- and wool–SO3H supported with manganese dioxide nanostructures." RSC Advances 5, no. 112 (2015): 91966–73. http://dx.doi.org/10.1039/c5ra16608j.

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A novel domino oxidative Ugi-type three-component reaction (OU-3CR) of aromatic hydrocarbons of petroleum naphtha has been investigated using two biopolymer supported MnO<sub>2</sub> nanostructured catalysts, MnO<sub>2</sub>@cellulose–SO<sub>3</sub>H and MnO<sub>2</sub>@wool–SO<sub>3</sub>H.

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33

Vrbová, Eva, Jitka Pecková, and Miroslav Marek. "Preparation and Utilization of a Biosensor Based on Galactose Oxidase." Collection of Czechoslovak Chemical Communications 57, no. 11 (1992): 2287–94. http://dx.doi.org/10.1135/cccc19922287.

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An enzyme electrode for D-galactose determination was prepared by fixation of a carrier with immobilized galactose oxidase (E.C. 1.1.3.9) or coimmobilized galactose oxidase and catalase (E.C. 1.11.1.6) to a Clark-type oxygen sensor. The enzymes were immobilized either on a partially hydrolyzed nylon mesh or on a native collagen membrane using the Ugi reaction with cyclohexyl isocyanide and glutaraldehyde. The biosensors were characterized by the specific activity of the immobilized galactose oxidase, the apparent Michaelis constant KM(app.), and the stability expressed by time and a number of

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34

Timmer, Mattie S. M., Steven H. L. Verhelst, Gijsbert M. Grotenbreg, Mark Overhand, and Herman S. Overkleeft. "Carbohydrates as versatile platforms in the construction of small compound libraries." Pure and Applied Chemistry 77, no. 7 (2005): 1173–81. http://dx.doi.org/10.1351/pac200577071173.

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This paper presents our recent results concerning the use of carbohydrates as cheap, chiral, and enantiopure starting materials in the construction of a variety of densely functionalized molecules. The compatibility of ring-closing metathesis with standard carbohydrate chemistry is demonstrated in the synthesis of new stereoisomers of deoxystreptamine and neamine–important building blocks for the generation of synthetic aminoglycosides with potential antibacterial activity. Ring-closing metathesis is also a key step in the rapid synthesis of new indolizidines and quinolizidines, and in a new s

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35

Vrbová, Eva, and Miroslav Marek. "Preparation of enzyme electrode for D-glucose determination by immobilization of glucose oxidase on collagen membrane." Collection of Czechoslovak Chemical Communications 55, no. 10 (1990): 2568–74. http://dx.doi.org/10.1135/cccc19902568.

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An enzyme electrode for the determination of D-glucose was prepared by immobilization of glucose oxidase (EC 1.1.3.4.) on an activated collagen membrane using glutaraldehyde and the Ugi reaction resp. and by subsequent fixation of the membrane to an oxygen sensor of the Clark type. Two different procedures for the modification of the support, the composition of the reaction mixture and the immobilization time were examined. The electrode prepared was tested as regards the effect of pH and temperature on the magnitude of the response. The range of the linear dependence of the sensor response on

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36

Naqvi, Tahira, Asif Amin, Shujat Ali, et al. "In vitro and In silico Evaluation of Structurally Diverse Benzyl-pyrrolidine-3-ol Analogues as Apoptotic Agents via Caspase Activation." Acta Chimica Slovenica 68, no. 3 (2021): 667–82. http://dx.doi.org/10.17344/acsi.2021.6684.

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The activation of caspases is central to apoptotic process in living systems. Defects in apoptosis have been implicated with carcinogenesis. Need to develop smart agents capable of inducing apoptosis in tumor cells is obvious. With this motive, diversity oriented synthesis of 1-benzylpyrrolidin-3-ol analogues was envisaged. The multi component Ugi reaction synthesized library of electronically diverse analogues was explored for cytotoxic propensity towards a panel of human cancer cell lines at 10 μM. The lead compounds exhibit a selective cytotoxicity towards HL-60 cells as compared to cell li

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37

Vittal, R., C. Paul, C. B. Hill, and G. L. Hartman. "Characterization and Quantification of Fungal Colonization of Phakopsora pachyrhizi in Soybean Genotypes." Phytopathology® 104, no. 1 (2014): 86–94. http://dx.doi.org/10.1094/phyto-12-12-0334-r.

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Soybean rust, caused by the fungus Phakopsora pachyrhizi, is an economically important disease of soybean with potential to cause severe epidemics resulting in significant yield losses. Host resistance is one of the management tools to control this disease. This study compared soybean genotypes exhibiting immunity, complete and incomplete resistance, and susceptibility to an isolate of P. pachyrhizi based on visual assessment of reaction type, other visual traits such as sporulation, quantitative measurements of the amount of fungal DNA (FDNA) present in leaf tissues, and data on infection and

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38

Paul, C., C. B. Hill, and G. L. Hartman. "Comparisons of Visual Rust Assessments and DNA Levels of Phakopsora pachyrhizi in Soybean Genotypes Varying in Rust Resistance." Plant Disease 95, no. 8 (2011): 1007–12. http://dx.doi.org/10.1094/pdis-10-10-0729.

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Soybean resistance to Phakopsora pachyrhizi, the cause of soybean rust, has been characterized by the following three infection types: (i) immune response (IM; complete resistance) with no visible lesions, (ii) resistant reaction with reddish brown (RB) lesions (incomplete resistance), and (iii) susceptible reaction with tan-colored (TAN) lesions. Based on visual assessments of these phenotypes, single gene resistance in soybean to P. pachyrhizi has been documented, but colonization within infected tissues based on fungal DNA (FDNA) levels in different soybean genotypes had not been analyzed.

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39

Nahar, Nusrat, and Ridwan Bin Rashid. "Phylogenetic Analysis of Antibiotic Resistance Genes and Virulence Genes of Klebsiella species in silico." Dhaka University Journal of Pharmaceutical Sciences 16, no. 1 (2017): 119–27. http://dx.doi.org/10.3329/dujps.v16i1.33389.

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A total of twelve isolates were screened for virulence and antibiotic resistance genes associated with Klebsiella pneumoniae infections. Virulence and antibiotic resistance genes were detected by in silico PCR amplification. Iron uptake protein entB was detected in 66.67% (n=8) of the isolates while no isolate was found to harbour chelating agent irp2. Iron uptake system kfu, involved in purulent tissue infections and capsule formation, was identified in 25% (n=3) of the isolates. Regulator of mucoid phenotype A, rmpA was not found in any of the isolates. The wabG gene, responsible for urinary

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40

Angelia, Ika Okhtora, and Abd Azis Hasan. "PENGARUH LAMA PERENDAMAN DAN KONSENTRASI NATRIUM METABISULFIT TERHADAP KANDUNGAN VITAMIN C DAN TINGKAT KECERAHAN DALAM PEMBUATAN TEPUNG UBI JALAR, TEPUNG JAGUNG DAN TEPUNG SINGKONG." Jurnal Technopreneur (JTech) 6, no. 2 (2018): 67. http://dx.doi.org/10.30869/jtech.v6i2.200.

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The types of plants commonly used to making flour include tubers that have carbohydrates that resemble as wheat, are sweet potatoes, potatoes, corn, and cassava. The problem often faced by food containing carbohydrates is easy to a browning reaction because of the activity of polyphenols and oxidation enzymes which can convert polyphenols into polycarbonate insulation. The defective that causes color changes during storage can be overcome by using additives that are standard and safe for consumption such as Natrium Metabisulfite. The effect of soaking time on Natrium Metabisulfite on the whiti

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41

Xie, Lan-Gui, and Darren J. Dixon. "Iridium-catalyzed reductive Ugi-type reactions of tertiary amides." Nature Communications 9, no. 1 (2018). http://dx.doi.org/10.1038/s41467-018-05192-7.

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42

Tanaka, Yusuke, Kousuke Hidaka, Tomoaki Hasui, and Michinori Suginome. "ChemInform Abstract: B(OMe)3as a Nonacidic Iminium Ion Generator in Mannich- and Ugi-Type Reactions." ChemInform 40, no. 28 (2009). http://dx.doi.org/10.1002/chin.200928063.

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43

Ngouansavanh, Tifelle, and Jieping Zhu. "IBX-Mediated Oxidative Ugi-Type Multicomponent Reactions. Application to the N and C1 Functionalization of Tetrahydroisoquinoline." ChemInform 38, no. 46 (2007). http://dx.doi.org/10.1002/chin.200746122.

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44

Cioc, Razvan C., Hans D. Preschel, Gydo van der Heijden, Eelco Ruijter, and Romano V. A. Orru. "ChemInform Abstract: Trityl Isocyanide as a Mechanistic Probe in Multicomponent Chemistry: Walking the Line Between Ugi- and Strecker-Type Reactions." ChemInform 47, no. 43 (2016). http://dx.doi.org/10.1002/chin.201643042.

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45

Ke, Di, You Wu, Lei Zhang, Jiaan Shao, Yongping Yu, and wenteng chen. "Group-Assisted-Purification Chemistry Strategy for the Efficient Assembly of Cyclic Fused Pyridinones." Synthesis, September 1, 2021. http://dx.doi.org/10.1055/a-1628-5304.

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A group-assisted-purification (GAP) chemistry strategy based Ugi four-center three-component reaction (Ugi-4C-3CR) was explored. The reaction proceeded well to deliver the cyclic fused pyridinones selectively. Moreover, the reaction condition was mild and avoided additional chromatography or recrystallization work-up. Also, wide variations in substrates, such as anilines and aliphatic amines as well as amino alcohols and amino acid esters were all tolerated and achieved in good to excellent yields. Importantly, ladder-type cyclic fused pyridinones can be further constructed with excellent yiel

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46

Kurniawati, Fivy, Nanang Munif Yasin, Amila Dina, Sanses Atana, and Sarah Nabila Hakim. "Kajian Adverse Drug Reactions Terkait Interaksi Obat di Bangsal Rawat Inap Rumah Sakit Akademik UGM." JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) 10, no. 4 (2021). http://dx.doi.org/10.22146/jmpf.60228.

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Adverse Drug Reactions (ADRs) is one of the causes of patient’s prolonged length of stay in the hospital and drug interactions can be included as one of the causes of the cause of ADRs. ADR related to drug interactions is a clinical problem that requires proper prevention. This study aimed to identify potential drug interactions also identify adverse drug reactions (ADRs) related to drug interactions in hospitalized patients at Universitas Gadjah Mada Teaching Hospital. This cross-sectional study used retrospective data collection through patient’s medical records from January to June 2018. Pa

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Jabeen, Farhat, Rajeev Gupta, Archana Nagpal, Vishal Katna, Vishwas Mahajan, and Pragya Bali. "Comparative Study on Color Stability of Denture Reline Polymers when Using Microwave and Chemical Disinfection." Journal of Advances in Medicine and Medical Research, April 3, 2019, 1–7. http://dx.doi.org/10.9734/jammr/2019/v29i530085.

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Abstract:

This study investigated the color stability of reline resin after two methods of disinfection i.e microwave disinfection and chemical disinfection. A stainless steel mold with a breakaway compartment (10 mm in diameter by 0.7 mm thickness) was made to fabricate specimens of various resins. Each material was mixed according to manufacturer’s instructions and applied into the mold. Prior to color stability testing, specimens were cleaned in distilled water for 20 minutes to kill any microorganisms that may had contaminated the discs during fabrication. And then specimens were immersed in Sodium

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Zhang, Siqin, Xiucai Zhang, Qing Wu, et al. "Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China." Antimicrobial Resistance & Infection Control 8, no. 1 (2019). http://dx.doi.org/10.1186/s13756-019-0615-2.

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Abstract Background Klebsiella pneumoniae-induced pyogenic liver abscess (KP-PLA) has emerged as a life-threatening disease worldwide. However, to date, a limited number of scholars have attempted to systematically elucidate the characteristics of KP-PLA. The aim of the present study was to analyze clinical, microbiological, and molecular epidemiological characteristics of KP-PLA patients in Southeastern China. Methods The KP-PLA cases from a tertiary teaching hospital in China from January 2016 to December 2017 were systemically studied and elucidated comprehensively. The virulence factors, r

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