Academic literature on the topic 'Uhplc-Hrms/ms'

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Journal articles on the topic "Uhplc-Hrms/ms"

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La Maida, Nunzia, Manuela Pellegrini, Esther Papaseit, et al. "Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS." International Journal of Molecular Sciences 21, no. 24 (2020): 9414. http://dx.doi.org/10.3390/ijms21249414.

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The consumption of synthetic cannabinoids (SCs) has significantly increased in the last decade and the analysis of SCs and their metabolites in human specimens is gaining interest in clinical and forensic toxicology. A pilot study has been carried out using a combination of an initial last generation gas chromatography-mass spectrometry (GC-MS) screening method for the determination of JWH-122, JWH-210, UR-144) in oral fluid (OF) of consumers and an ultra-high performance liquid chromatography high resolution mass spectrometry (UHPLC-HRMS) confirmatory method for the quantification of the pare
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Antonio, Ananda da Silva, Davi Santos Oliveira, Gustavo Ramalho Cardoso dos Santos, Henrique Marcelo Gualberto Pereira, Larissa Silveira Moreira Wiedemann, and Valdir Florêncio da Veiga-Junior. "UHPLC-HRMS/MS on untargeted metabolomics: a case study with Copaifera (Fabaceae)." RSC Advances 11, no. 40 (2021): 25096–103. http://dx.doi.org/10.1039/d1ra03163e.

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Matey, José Manuel, Adrián López-Fernández, Carmen García-Ruiz, Gemma Montalvo, Félix Zapata, and María A. Martínez. "Identification of 2C-B in Hair by UHPLC-HRMS/MS. A Real Forensic Case." Toxics 9, no. 7 (2021): 170. http://dx.doi.org/10.3390/toxics9070170.

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The analysis of drugs of abuse in hair and other biological matrices of forensic interest requires great selectivity and sensitivity. This has been traditionally achieved through target analysis, using one or more analytical methods that include different preanalytical stages, and more complex procedures followed by toxicological laboratories. There is no exception with 2C-series drugs, such as 2C-B, a new psychoactive substance (NPS), which use has emerged and significantly increased, year by year, in the last decades. Continuously new analytical methods are required to selectively detect and
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Jiang, Xiaofang, Lin Zhou, Lihua Zuo, et al. "Pharmacokinetics and Metabolism Research of Shenkang Injection in Rats Based on UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS." Drug Design, Development and Therapy Volume 14 (May 2020): 1837–50. http://dx.doi.org/10.2147/dddt.s235646.

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Liu, Rongxia, Ziyan Zhao, Shengjun Dai, Xin Che, and Wanhui Liu. "Identification and Quantification of Bioactive Compounds in Diaphragma juglandis Fructus by UHPLC-Q-Orbitrap HRMS and UHPLC-MS/MS." Journal of Agricultural and Food Chemistry 67, no. 13 (2019): 3811–25. http://dx.doi.org/10.1021/acs.jafc.8b06890.

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Kasiotis, Konstantinos M., Eirini Baira, Electra Manea-Karga, Dimitra Nikolopoulou, Konstantinos Ganas, and Kyriaki Machera. "Investigating a human pesticide intoxication incident: The importance of robust analytical approaches." Open Chemistry 19, no. 1 (2021): 107–18. http://dx.doi.org/10.1515/chem-2021-0193.

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Abstract A human intoxication incident attributed to pesticide abuse was investigated using cutting-edge analytical methodologies. An LC-ESI-MS/MS method, based on a hybrid solid-phase extraction protocol (hybrid-SPE), was applied for the detection and quantification of several pesticides and metabolites in human biological fluids. Concomitantly, an UHPLC-HRMS method was applied to investigate potential metabolites, assisted by a complementary GC-MS method to elucidate the presence of plausible pesticides co-formulants. The LC-ESI-MS/MS method exhibited acceptable mean recoveries at the lower
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Brakni, Rafika, Monia Ali Ahmed, Pauline Burger, et al. "UHPLC-HRMS/MS Based Profiling of Algerian Lichens and Their Antimicrobial Activities." Chemistry & Biodiversity 15, no. 4 (2018): e1800031. http://dx.doi.org/10.1002/cbdv.201800031.

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Uekusa, Shusuke, Mayu Onozato, Tatsuya Sakamoto, et al. "Development of a Derivatization Reagent with a 2-Nitrophenylsulfonyl Moiety for UHPLC-HRMS/MS and Its Application to Detect Amino Acids Including Taurine." Molecules 26, no. 12 (2021): 3498. http://dx.doi.org/10.3390/molecules26123498.

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Taurine (Tau) has some important ameliorating effects on human health and is present in bivalve. For the selective analysis of Tau with other amino acids, we designed a derivatization reagent, 2,5-dioxopyrrolidin-1-yl(4-(((2-nitrophenyl)sulfonyl)oxy)-6-(3-oxomorpholino)quinoline-2-carbonyl)pyrrolidine-3-carboxylate (Ns-MOK-β-Pro-OSu). After derivatization with Ns-MOK-β-Pro-OSu, amino acids with Tau in Japanese littleneck clams were determined through ultra-high-performance-liquid chromatography with high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) using an octadecyl silica column. We c
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Strano Rossi, Sabina, Luca Anzillotti, Erika Castrignanò, Giampietro Frison, Flavio Zancanaro, and Marcello Chiarotti. "UHPLC-MS/MS and UHPLC-HRMS identification of zolpidem and zopiclone main urinary metabolites and method development for their toxicological determination." Drug Testing and Analysis 6, no. 3 (2013): 226–33. http://dx.doi.org/10.1002/dta.1470.

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Brescia, Francesca, Anthi Vlassi, Ana Bejarano, et al. "Characterisation of the Antibiotic Profile of Lysobacter capsici AZ78, an Effective Biological Control Agent of Plant Pathogenic Microorganisms." Microorganisms 9, no. 6 (2021): 1320. http://dx.doi.org/10.3390/microorganisms9061320.

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Determining the mode of action of microbial biocontrol agents plays a key role in their development and registration as commercial biopesticides. The biocontrol rhizobacterium Lysobacter capsici AZ78 (AZ78) is able to inhibit a vast array of plant pathogenic oomycetes and Gram-positive bacteria due to the release of antimicrobial secondary metabolites. A combination of MALDI-qTOF-MSI and UHPLC-HRMS/M was applied to finely dissect the AZ78 metabolome and identify the main secondary metabolites involved in the inhibition of plant pathogenic microorganisms. Under nutritionally limited conditions,
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Dissertations / Theses on the topic "Uhplc-Hrms/ms"

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Fougère, Laëtitia. "Signature moléculaire de milieux complexes : Stratégie de couplage à la spectrométrie de masse et interprétation des données." Thesis, Orléans, 2019. http://www.theses.fr/2019ORLE2014.

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La composition en métabolites des organismes vivants évolue lorsqu’ils sont soumis à des modifications environnementales et diffère d’une espèce à l’autre. L’objectif de cette thèse a été de déployer des stratégies de couplages chromatographiques avec la spectrométrie de masse et de traitement des données MS pour répondre aux différentes problématiques rencontrées en termes de caractérisation, quantification et comparaison du contenu moléculaire de milieux complexes.Ces études ont permis en premier lieu, de développer des méthodes de déréplication par TLC/MS pour identifier rapidement les molé
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Girard, Léa. "Quorum Sensing in Vibrio spp. : AHL diversity, temporal dynamic and niche partitioning." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066650/document.

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Chez les Vibrio spp., le QS est impliqué dans de nombreuses fonctions comme la colonisation de niche écologiques, les stratégies de survie ou encore la virulence. Cependant, pour la majorité des espèces de Vibrio, la diversité des AHLs produites reste largement sous-estimée et l'étude du QS est encore limitée à quelques espèces modèles ou pathogènes. Toutefois, dans les environnements aquatiques, ces espèces sont minoritaires et les espèces les plus abondantes ne sont que très peu étudiées. Nos résultats ont révélé une importante diversité d'AHLs mais aussi, de façon surprenante, une hétérogén
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