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Journal articles on the topic 'Ultra-High-Field (UHF) Magnetic Resonance Imaging (MRI)'

Author: Grafiati

Published: 14 March 2023

Last updated: 31 July 2025

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1

Bolin Qin and Jia-Hong Gao. "Ultrahigh-Field Magnetic Resonance Imaging: Current Status and Perspectives." Acta Physica Sinica 74, no. 7 (2025): 0. https://doi.org/10.7498/aps.74.20241759.

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Magnetic resonance imaging (MRI) is one of the most important imaging modalities used in clinical radiology research and diagnosis due to its non-invasive nature, absence of ionizing radiation, high soft tissue contrast, and diverse imaging capabilities. However, traditional MRI is limited by a relatively low signal-to-noise ratio (SNR), which can be enhanced by increasing the strength of the main magnetic field. Ultra-high field MRI (UHF-MRI), an emerging technology, typically refers to MRI systems with a main magnetic field strength of 7 T or higher. Compared to conventional MRI, UHF-MRI imp

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Chang, Catie, Erika P. Raven, and Jeff H. Duyn. "Brain–heart interactions: challenges and opportunities with functional magnetic resonance imaging at ultra-high field." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 374, no. 2067 (2016): 20150188. http://dx.doi.org/10.1098/rsta.2015.0188.

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Magnetic resonance imaging (MRI) at ultra-high field (UHF) strengths (7 T and above) offers unique opportunities for studying the human brain with increased spatial resolution, contrast and sensitivity. However, its reliability can be compromised by factors such as head motion, image distortion and non-neural fluctuations of the functional MRI signal. The objective of this review is to provide a critical discussion of the advantages and trade-offs associated with UHF imaging, focusing on the application to studying brain–heart interactions. We describe how UHF MRI may provide contrast and reso

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3

Roche, D., C. Michel, P. Daudé, et al. "AB1098 STRUCTURAL ELEMENTS OF THE KNEE ENTHESES ASSESSED IN HEALTHY SUBJECTS WITH ULTRA HIGH FIELD MRI (150 MICRONS)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1838. http://dx.doi.org/10.1136/annrheumdis-2020-eular.1191.

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Background:Fibrocartilaginous enthesis is composed of different histological zones which are commonly referred to the tendon distal extremity (a lamellar tissue with a low cell density, collagen and connective tissue), the fibrocartilaginous zone (with chondrocytes), a progressively mineralized zone and the bone. The MRI visualization of the water content of entheses is challenging given the very short relation time so that entheses has been very poorly assessed using MRI (1).Objectives:The main objective of the study was to assess the structural elements of the knee enthesis based on the quan

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Seo, Jeung-Hoon, Yeji Han, and Jun-Young Chung. "A Comparative Study of Birdcage RF Coil Configurations for Ultra-High Field Magnetic Resonance Imaging." Sensors 22, no. 5 (2022): 1741. http://dx.doi.org/10.3390/s22051741.

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Improvements in transmission and reception sensitivities of radiofrequency (RF) coils used in ultra-high field (UHF) magnetic resonance imaging (MRI) are needed to reduce specific absorption rates (SAR) and RF power deposition, albeit without applying high-power RF. Here, we propose a method to simultaneously improve transmission efficiency and reception sensitivity of a band-pass birdcage RF coil (BP-BC RF coil) by combining a multi-channel wireless RF element (MCWE) with a high permittivity material (HPM) in a 7.0 T MRI. Electromagnetic field (EM-field) simulations, performed using two types

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Isaacs, Bethany R., Max C. Keuken, Anneke Alkemade, Yasin Temel, Pierre-Louis Bazin, and Birte U. Forstmann. "Methodological Considerations for Neuroimaging in Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease Patients." Journal of Clinical Medicine 9, no. 10 (2020): 3124. http://dx.doi.org/10.3390/jcm9103124.

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Deep brain stimulation (DBS) of the subthalamic nucleus is a neurosurgical intervention for Parkinson’s disease patients who no longer appropriately respond to drug treatments. A small fraction of patients will fail to respond to DBS, develop psychiatric and cognitive side-effects, or incur surgery-related complications such as infections and hemorrhagic events. In these cases, DBS may require recalibration, reimplantation, or removal. These negative responses to treatment can partly be attributed to suboptimal pre-operative planning procedures via direct targeting through low-field and low-re

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Wang, Xi, Shao Ying Huang, and Abdulkadir C. Yucel. "Uncertainty Quantification in SAR Induced by Ultra-High-Field MRI RF Coil via High-Dimensional Model Representation." Bioengineering 11, no. 7 (2024): 730. http://dx.doi.org/10.3390/bioengineering11070730.

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As magnetic field strength in Magnetic Resonance Imaging (MRI) technology increases, maintaining the specific absorption rate (SAR) within safe limits across human head tissues becomes challenging due to the formation of standing waves at a shortened wavelength. Compounding this challenge is the uncertainty in the dielectric properties of head tissues, which notably affects the SAR induced by the radiofrequency (RF) coils in an ultra-high-field (UHF) MRI system. To this end, this study introduces a computational framework to quantify the impacts of uncertainties in head tissues’ dielectric pro

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Periyasamy, M., and R. Dhanasekaran. "IMPLEMENTATION OF RADIO FREQUENCY IDENTIFICATION DEVICES IN 0.3 TESLA MAGNETIC RESONANCE IMAGING AND COMPUTED TOMOGRAPHY." Biomedical Engineering: Applications, Basis and Communications 26, no. 06 (2014): 1450069. http://dx.doi.org/10.4015/s1016237214500690.

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The aim of this work was to assess two issues concerning magnetic resonance imaging (MRI) including device functionality and image artifacts for the presence of ultra high frequency (UHF) radio frequency identification (RFID) devices in connection with 0.3 Tesla at 12.7 MHz MRI and computed tomography (CT) scanning. A total of 15 samples of RFID tags with two dissimilar sizes (wristband and ID card types) were tested. The tags were exposed to a several numbers of MR-imaging conditions during MRI examination and X-rays of CT scan. During the test, the tags were oriented in three different direc

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8

Garcia, Maíra M., Khallil T. Chaim, Maria C. G. Otaduy, et al. "Investigating the influence of dielectric pads in 7T magnetic resonance imaging – simulated and experimental assessment." Current Directions in Biomedical Engineering 6, no. 3 (2020): 24–27. http://dx.doi.org/10.1515/cdbme-2020-3007.

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AbstractDipole radiofrequency (RF) elements have been successfully used to compose multi-channel RF coils for ultrahigh fields (UHF) magnetic resonance imaging (MRI). As magnetic components of RF fields (B1) can be very inhomogeneous at UHF (B0≥7T), dielectric pads with high dielectric constants were proposed to improve the B1 efficiency and homogeneity [1]. Dielectric pads can be used as a passive B1 shimmimg technique thanks to inducing a strong secondary magnetic field in their vicinity. The use of such dielectric pads affect not only the B1 field but also the electric field. This in turn a

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Seo, Jeung-Hoon, Young-Seung Jo, Chang-Hyun Oh, and Jun-Young Chung. "A New Combination of Radio-Frequency Coil Configurations Using High-Permittivity Materials and Inductively Coupled Structures for Ultrahigh-Field Magnetic Resonance Imaging." Sensors 22, no. 22 (2022): 8968. http://dx.doi.org/10.3390/s22228968.

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In ultrahigh-field (UHF) magnetic resonance imaging (MRI) system, the RF power required to excite the nuclei of the target object increases. As the strength of the main magnetic field (B0 field) increases, the improvement of the RF transmit field (B1+ field) efficiency and receive field (B1− field) sensitivity of radio-frequency (RF) coils is essential to reduce their specific absorption rate and power deposition in UHF MRI. To address these problems, we previously proposed a method to simultaneously improve the B1+ field efficiency and B1− field sensitivity of 16-leg bandpass birdcage RF coil

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Woo, Myung Kyun, Lance DelaBarre, Matt Waks, et al. "A 16-Channel Dipole Antenna Array for Human Head Magnetic Resonance Imaging at 10.5 Tesla." Sensors 21, no. 21 (2021): 7250. http://dx.doi.org/10.3390/s21217250.

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For ultra-high field and frequency (UHF) magnetic resonance imaging (MRI), the associated short wavelengths in biological tissues leads to penetration and homogeneity issues at 10.5 tesla (T) and require antenna transmit arrays for efficiently generated 447 MHz B1+ fields (defined as the transmit radiofrequency (RF) magnetic field generated by RF coils). Previously, we evaluated a 16-channel combined loop + dipole antenna (LD) 10.5 T head array. While the LD array configuration did not achieve the desired B1+ efficiency, it showed an improvement of the specific absorption rate (SAR) efficiency

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Hernandez, Daniel, Taewoo Nam, Yonghwa Jeong, Donghyuk Kim, and Kyoung-Nam Kim. "Study on the Effect of Non-Symmetrical Current Distribution Controlled by Capacitor Placement in Radio-Frequency Coils for 7T MRI." Biosensors 12, no. 10 (2022): 867. http://dx.doi.org/10.3390/bios12100867.

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In this paper, we present a study on the effects of varying the position of a single tuning capacitor in a circular loop coil as a mechanism to control and produce non-symmetric current distribution, such that could be used for magnetic resonance imaging (MRI) operating at ultra-high frequency (UHF). This study aims to demonstrate that the position of the tuning capacitor of a circular loop could improve the coupling between adjacent coils, used to optimize transmission field uniformity or intensity, improve signal-to-noise ratio (SNR) or specific absorption rate (SAR). A typical loop coil use

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Bourara, A., M. A. Hostin, E. Soldati, et al. "POS1355 COMBINED ASSESSMENT OF CARTILAGE AND SUBCHONDRAL BONE IN OSTEOARTHRITIC AND NON-OSTEOARTHRITIC KNEE COMPARTMENTS: A ULTRA-HIGH FIELD MRI STUDY." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1029.1–1029. http://dx.doi.org/10.1136/annrheumdis-2023-eular.236.

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BackgroundKnee osteoarthritis (OA) is one of the most common degenerative diseases causing disability in elderly people. Although X-ray radiography is widely used as a diagnostic tool, several limitations have been identified[1].MRI is a non-invasive imaging method widely used in order to assess articular and periarticular structures of the knee joint[2].However, the image resolution provided by conventional MRI is not high enough to assess subchondral bone so that ultra-high field MRI (7 Tesla) has been proposed as an alternative of interest to compute bone microarchitectural parameters[3].Ob

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Li, Xin, Xiao-Hong Zhu, and Wei Chen. "A Quantitative Comparison of 31P Magnetic Resonance Spectroscopy RF Coil Sensitivity and SNR between 7T and 10.5T Human MRI Scanners Using a Loop-Dipole 31P-1H Probe." Sensors 24, no. 17 (2024): 5793. http://dx.doi.org/10.3390/s24175793.

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In vivo phosphorus-31 (31P) magnetic resonance spectroscopy (MRS) imaging (MRSI) is an important non-invasive imaging tool for studying cerebral energy metabolism, intracellular nicotinamide adenine dinucleotide (NAD) and redox ratio, and mitochondrial function. However, it is challenging to achieve high signal-to-noise ratio (SNR) 31P MRS/MRSI results owing to low phosphorus metabolites concentration and low phosphorous gyromagnetic ratio (γ). Many works have demonstrated that ultrahigh field (UHF) could significantly improve the 31P-MRS SNR. However, there is a lack of studies of the 31P MRS

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Chen, Yinching Iris, Ilknur Ay, Francesca Marturano, Peter Fuller, Hernan Millan, and Giorgio Bonmassar. "A Polymer Thick Film on an Organic Substrate Grid Electrode and an Open-Source Recording System for UHF MRI: An Imaging Study." Sensors 24, no. 16 (2024): 5214. http://dx.doi.org/10.3390/s24165214.

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Electrocorticography (ECoG) is a critical tool in preclinical neuroscience research for studying global network activity. However, integrating ECoG with functional magnetic resonance imaging (fMRI) has posed challenges, due to metal electrode interference with imaging quality and heating around the metallic electrodes. Here, we introduce recent advancements in ECoG grid development that utilize a polymer-thick film on an organic substrate (PTFOS). PTFOS offers notable advantages over traditional ECoG grids. Firstly, it significantly reduces imaging artifacts, ensuring minimal interference with

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Wang, Qiuliang, Jianhua Liu, Jinxing Zheng, et al. "Progress of ultra-high-field superconducting magnets in China." Superconductor Science and Technology 35, no. 2 (2021): 023001. http://dx.doi.org/10.1088/1361-6668/ac3f9b.

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Abstract High magnetic fields play a critical role in the development of modern science and technology, breeding many significant scientific discoveries and boosting the generation of new technologies. In the last few years, China has undertaken a great deal of work on the application of ultra-high-field (UHF) superconducting magnet technology, such as for the Synergetic Extreme Condition User Facility in Beijing, the UHF nuclear magnetic resonance/magnetic resonance imaging, nuclear fusion energy, particle accelerator, and so on. This paper reports the research status of UHF superconducting m

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Weldon, Kimberly B., and Cheryl A. Olman. "Forging a path to mesoscopic imaging success with ultra-high field functional magnetic resonance imaging." Philosophical Transactions of the Royal Society B: Biological Sciences 376, no. 1815 (2020): 20200040. http://dx.doi.org/10.1098/rstb.2020.0040.

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Functional magnetic resonance imaging (fMRI) studies with ultra-high field (UHF, 7+ Tesla) technology enable the acquisition of high-resolution images. In this work, we discuss recent achievements in UHF fMRI at the mesoscopic scale, on the order of cortical columns and layers, and examine approaches to addressing common challenges. As researchers push to smaller and smaller voxel sizes, acquisition and analysis decisions have greater potential to degrade spatial accuracy, and UHF fMRI data must be carefully interpreted. We consider the impact of acquisition decisions on the spatial specificit

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Savukov, Igor, Young Jin Kim, and Shaun Newman. "High-resolution ultra-low field magnetic resonance imaging with a high-sensitivity sensing coil." Journal of Applied Physics 132, no. 17 (2022): 174503. http://dx.doi.org/10.1063/5.0123692.

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We present high-resolution magnetic resonance imaging (MRI) at ultra-low field (ULF) with a proton Larmor frequency of around 120 kHz. The key element is a specially designed high-sensitivity sensing coil in the shape of a solenoid with a few millimeter gap between windings to decrease the proximity effect and, hence, increase the coil’s quality ([Formula: see text]) factor and sensitivity. External noise is strongly suppressed by enclosing the sensing coil in a copper cylindrical shield, large enough not to negatively affect the coil’s [Formula: see text] factor and sensitivity, measured to b

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Altaf, Ahmed, Muhammad Waqas Saeed Baqai, Faiza Urooj, et al. "Intraoperative use of ultra-low-field, portable magnetic resonance imaging – first report." Surgical Neurology International 14 (June 23, 2023): 212. http://dx.doi.org/10.25259/sni_124_2023.

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Background: Intraoperative use of portable magnetic resonance imaging (pMRI) has become a valuable tool in a surgeon’s arsenal since its inception. It allows intraoperative localization of tumor extent and identification of residual disease, hence maximizing tumor resection. Its utility has been widespread in high-income countries for the past 20 years, but in lower-middle-income countries (LMIC), it is still not widely available due to several reasons, including cost constraints. The use of intraoperative pMRI may be a cost-effective and efficient substitute for conventional MRI machines. The

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Willemink, Martin J., Bram F. Coolen, Hadrien Dyvorne, et al. "Ultra-high resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T." PLOS ONE 15, no. 12 (2020): e0241779. http://dx.doi.org/10.1371/journal.pone.0241779.

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Accurate quantification and characterization of atherosclerotic plaques with MRI requires high spatial resolution acquisitions with excellent image quality. The intrinsically better signal-to-noise ratio (SNR) at high-field clinical 7T compared to the widely employed lower field strengths of 1.5 and 3T may yield significant improvements to vascular MRI. However, 7T atherosclerosis imaging also presents specific challenges, related to local transmit coils and B1 field inhomogeneities, which may overshadow these theoretical gains. We present the development and evaluation of 3D, black-blood, ult

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Qin, Lang, and Jia-Hong Gao. "New avenues for functional neuroimaging: ultra-high field MRI and OPM-MEG." Psychoradiology 1, no. 4 (2021): 165–71. http://dx.doi.org/10.1093/psyrad/kkab014.

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Abstract Functional brain imaging technology has developed rapidly in recent years. On the one hand, high-field 7-Tesla magnetic resonance imaging (MRI) has excelled the limited spatial resolution of 3-Tesla MRI, allowing us to enter a new world of mesoscopic imaging from the macroscopic imaging of human brain functions. On the other hand, novel optical pumping magnetometer-magnetoencephalography (OPM-MEG) has broken down the technical barriers of traditional superconducting MEG, which brings imaging of neuronal electromagnetic signals from cortical imaging to whole-brain imaging. This article

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Salehi, F., BY Kwan, SM Mirsattari, et al. "P.127 Ultra-high field 7-Tesla magnetic resonance imaging and electroencephalography findings in epilepsy." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 48, s3 (2021): S55—S56. http://dx.doi.org/10.1017/cjn.2021.403.

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Background: Assessment of patients for temporal lobe epilepsy (TLE) surgery requires multimodality input, including EEG to ensure optimal surgical planning. Often EEG demonstrates abnormal foci not detected on clinical MRI. 7T MRI provides improved resolution and we investigated its utility to detect potential abnormalities associated with EEG. Methods: Images were acquired on 7T MRI scanner (N=13) in oatients with TLE. Evaluation of 7T imaging for focal abnormalities was performed. Correlation of 7T MRI findings with EEG of focal slowing or interictal epileptic spikes (IEDs) and seizures was

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Senft, Christian, Volker Seifert, Elvis Hermann, Kea Franz, and Thomas Gasser. "Usefulness of Intraoperative Ultra Low-field Magnetic Resonance Imaging in Glioma Surgery." Operative Neurosurgery 63, suppl_4 (2008): ONS257—ONS267. http://dx.doi.org/10.1227/01.neu.0000313624.77452.3c.

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Abstract Objective: The aim of this study was to demonstrate the usefulness of a mobile, intraoperative 0.15-T magnetic resonance imaging (MRI) scanner in glioma surgery. Methods: We analyzed our prospectively collected database of patients with glial tumors who underwent tumor resection with the use of an intraoperative ultra low-field MRI scanner (PoleStar N-20; Odin Medical Technologies, Yokneam, Israel/Medtronic, Louisville, CO). Sixty-three patients with World Health Organization Grade II to IV tumors were included in the study. All patients were subjected to postoperative 1.5-T imaging t

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Zhang, Lan. "5T MRI: Bridging innovation and whole-body clinical need." ASEAN Journal of Radiology 26, no. 2 (2025): 140–47. https://doi.org/10.46475/asean-jr.v26i2.950.

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This article introduces the clinical debut of whole-body 5T magnetic resonance imaging (MRI), a novel ultra-high-field system designed to bridge the gap between conventional 3T and 7T MRI. Developed through international collaboration, the 5T platform overcomes major technical barriers in RF design, field homogeneity, and SAR control, to enable stable, high-resolution imaging across the whole body. Clinical evidence demonstrates its superiority in multiple applications, including intracranial vascular imaging, cardiac and coronary assessment, and abdominal imaging. By delivering both ultra-hig

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Cheng, Guanzhe. "Research on Innovative Applications of MRI Technology in Medicine and Agriculture." Theoretical and Natural Science 80, no. 1 (2025): 7–19. https://doi.org/10.54254/2753-8818/2025.gl19714.

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Magnetic Resonance Imaging (MRI) serves as a crucial diagnostic tool, employing the principles of magnetic resonance to facilitate the non-invasive examination of various anatomical structures within the body. Through its ability to provide detailed images of soft tissues, MRI has become indispensable in modern medicine. This paper reviews both the advantages and limitations associated with MRI, while also exploring its innovative applications in the field of agriculture. Notably, MRI is utilized for analyzing crop root systems, allowing researchers to gain insights into plant health and growt

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Biju, Silvanose, and Tatjana N. Parac-Vogt. "Recent Advances in Lanthanide Based Nano-Architectures as Probes for Ultra High-Field Magnetic Resonance Imaging." Current Medicinal Chemistry 27, no. 3 (2020): 352–61. http://dx.doi.org/10.2174/0929867325666180201110244.

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Paramagnetic Lanthanide ions incorporated into nano- architectures are emerging as a versatile platform for Magnetic Resonance Imaging (MRI) contrast agents due to their strong contrast enhancement effects combined with the platform capability to include multiple imaging modalities. This short review examines the application of lanthanide based nanoarchitectures (nanoparticles and nano- assemblies) in the development of multifunctional probes for single and multimodal imaging involving high field MRI as one imaging modality.

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LIU Fan, JIANG Yuancheng, and GUO Hua. "A Review of High-Resolution 2D Diffusion Magnetic Resonance Imaging Techniques." Acta Physica Sinica 74, no. 11 (2025): 0. https://doi.org/10.7498/aps.74.20250235.

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Diffusion-weighted magnetic resonance imaging (DWI) holds significant value in neuroscience and clinical disease diagnosis. The most commonly used single-shot echo-planar imaging (EPI) for DWI is affected by static magnetic field (B<sub>0</sub>) inhomogeneity and T<sub>2</sub>/T<sub>2</sub><sup>*</sup> decay, leading to issues such as geometric distortion and low signal-to-noise ratio (SNR). To address these challenges, researchers have developed more advanced high-resolution diffusion MRI techniques. This article provides a comprehensive review

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Scheffler, Max, Rares Salomir, Enrique Maturana, Marie-Louise Montandon, Enikö V. Kövari, and Sven Haller. "Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging." Neuroradiology 63, no. 9 (2021): 1569–73. http://dx.doi.org/10.1007/s00234-021-02717-8.

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AbstractCortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is known about their visibility on routinely used 3-T MRI. In this radiologic-pathologic correlation study, using 3-T post-mortem MRI, we searched for hippocampal CMI, in a double-blinded fashion, and found that only 4/36, or 11%, were clearly demonstrated on both radiological and histopathologica

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Takeda, Y., H. Maeda, K. Ohki, and Y. Yanagisawa. "Review of the temporal stability of the magnetic field for ultra-high field superconducting magnets with a particular focus on superconducting joints between HTS conductors." Superconductor Science and Technology 35, no. 4 (2022): 043002. http://dx.doi.org/10.1088/1361-6668/ac5645.

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Abstract Superconducting magnets used in applications such as magnetic resonance imaging (MRI) and nuclear magnetic resonance (NMR) require significant temporal magnetic field stability, which can be achieved when the MRI and NMR magnets are operated in the persistent current mode (persistent-mode) using superconducting joints. However, the ultra-high field MRI and NMR magnets are sometimes operated in the driven mode. Herein, we present an analysis of the temporal magnetic field drift and fluctuations observed for MRI and NMR magnets operating in the driven mode and an exploration of effectiv

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Lohmann, Philipp, Jan-Michael Werner, N. Shah, Gereon Fink, Karl-Josef Langen, and Norbert Galldiks. "Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients." Cancers 11, no. 2 (2019): 153. http://dx.doi.org/10.3390/cancers11020153.

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Imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI) provide valuable information about brain tumor patients. Particularly amino acid PET, advanced MRI techniques, and combinations thereof are of great interest for the non-invasive assessment of biological characteristics in patients with primary or secondary brain cancer. A methodological innovation that potentially advances research in patients with brain tumors is the increasing availability of hybrid PET/MRI systems, which enables the simultaneous acquisition of both imaging modalities. Further

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Waddington, David E. J., Thomas Boele, Richard Maschmeyer, Zdenka Kuncic, and Matthew S. Rosen. "High-sensitivity in vivo contrast for ultra-low field magnetic resonance imaging using superparamagnetic iron oxide nanoparticles." Science Advances 6, no. 29 (2020): eabb0998. http://dx.doi.org/10.1126/sciadv.abb0998.

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Magnetic resonance imaging (MRI) scanners operating at ultra-low magnetic fields (ULF; <10 mT) are uniquely positioned to reduce the cost and expand the clinical accessibility of MRI. A fundamental challenge for ULF MRI is obtaining high-contrast images without compromising acquisition sensitivity to the point that scan times become clinically unacceptable. Here, we demonstrate that the high magnetization of superparamagnetic iron oxide nanoparticles (SPIONs) at ULF makes possible relaxivity- and susceptibility-based effects unachievable with conventional contrast agents (CAs). We leverage

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S, Allen Counter, Peter Damberg, Sahar Nikkhou Aski, Kálmán Nagy, Cecilia Engmér Berglin, and Göran Laurell. "Experimental Fusion of Contrast Enhanced High-Field Magnetic Resonance Imaging and High-Resolution Micro-Computed Tomography in Imaging the Mouse Inner Ear." Open Neuroimaging Journal 9, no. 1 (2015): 7–12. http://dx.doi.org/10.2174/1874440001509010007.

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Objective: Imaging cochlear, vestibular, and 8th cranial nerve abnormalities remains a challenge. In this study, the membranous and osseous labyrinths of the wild type mouse inner ear were examined using volumetric data from ultra high-field magnetic resonance imaging (MRI) with gadolinium contrast at 9.4 Tesla and high-resolution micro-computed tomography (µCT) to visualize the scalae and vestibular apparatus, and to establish imaging protocols and parameters for comparative analysis of the normal and mutant mouse inner ear. Methods: For in vivo MRI acquisition, animals were placed in a Mille

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Garcia, Maíra M., Tiago R. Oliveira, Khallil T. Chaim, et al. "Thermal measurements of a muscle-mimicking phantom during ultra-high field magnetic resonance imaging." Current Directions in Biomedical Engineering 9, no. 1 (2023): 319–22. http://dx.doi.org/10.1515/cdbme-2023-1080.

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Abstract At ultra-high field MRI (Bo>7T) it is crucial to predict and control the patient safety. Commonly patient safety is controlled by the power deposited in the tissue (specific absorption rate - SAR). However, temperature distributions do not always correlate directly with SAR distributions, which makes temperature control also a crucial parameter to guarantee patient safety. In this work, temperature changes were accessed by MR thermometry, specifically by the proton resonance frequency shift technique (PRF). A phantom mimicking muscle tissue was used to evaluate the temperature rise

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Ahmad, Sheikh Faisal, Young Cheol Kim, Ick Chang Choi, and Hyun Deok Kim. "Recent Progress in Birdcage RF Coil Technology for MRI System." Diagnostics 10, no. 12 (2020): 1017. http://dx.doi.org/10.3390/diagnostics10121017.

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The radio frequency (RF) coil is one of the key components of the magnetic resonance imaging (MRI) system. It has a significant impact on the performance of the nuclear magnetic resonance (NMR) detection. Among numerous practical designs of RF coils for NMR imaging, the birdcage RF coil is the most popular choice from low field to ultra-high field MRI systems. In the transmission mode, it can establish a strong and homogeneous transverse magnetic field B1 for any element at its Larmor frequency. Similarly, in the reception mode, it exhibits extremely high sensitivity for the detection of even

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Eisenhut, Felix, Manuel Alexander Schmidt, Michael Buchfelder, Arnd Doerfler, and Sven-Martin Schlaffer. "Improved Detection of Cavernous Sinus Invasion of Pituitary Macroadenomas with Ultra-High-Field 7 T MRI." Life 13, no. 1 (2022): 49. http://dx.doi.org/10.3390/life13010049.

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To compare 7 T magnetic resonance imaging (MRI) of pituitary macroadenomas (PMA) with standard MRI and intraoperative findings regarding tumor detection, localization, size, and extension. Patients with suspected pituitary adenoma underwent pre-operative 1.5 T or 3 T and 7 T MRI; 14 patients with a PMA were included. A qualitative (lesion detection, location, cavernous sinus infiltration) and quantitative (lesion size, depth of cavernous sinus infiltration) analysis of 1.5 T, 3 T and 7 T MRI was performed and compared with intraoperative findings. Both 1.5/3 T and 7 T MRI enabled the detection

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Hernandez, Daniel, Taewoo Nam, Eunwoo Lee, et al. "Simulation Design of an Elliptical Loop-Microstrip Array for Brain Lobe Imaging with an 11.74 Tesla MRI System." Sensors 25, no. 13 (2025): 4021. https://doi.org/10.3390/s25134021.

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Magnetic resonance imaging (MRI) is a powerful medical imaging technique used for acquiring high-resolution anatomical and functional images of the human body. With the development of an 11.74 Tesla (T) human MRI system at our facility, we are designing novel radiofrequency (RF) coils optimized for brain imaging at ultra-high fields. To meet specific absorption rate (SAR) safety limits, this study focuses on localized imaging of individual brain lobes rather than whole-brain array designs. Conventional loop coils, while widely used, offer limited |B1|-field uniformity at 500 MHz—the Larmor fre

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Garcia, Maíra M., Tiago R. Oliveira, Daniel Papoti, et al. "Experimental and numerical investigations of a small animal coil for ultra-high field magnetic resonance imaging (7T)." Current Directions in Biomedical Engineering 5, no. 1 (2019): 525–28. http://dx.doi.org/10.1515/cdbme-2019-0132.

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AbstractThe purpose of this work was to develop and investigate a radiofrequency (RF) coil to perform image studies on small animals using the 7T magnetic resonance imaging (MRI) system, installed in the imaging platform in the autopsy room (Portuguese acronym PISA), at the University of Sao Paulo, Brazil, which is the unique 7T MRI scanner installed in South America. Due to a high demand to create new specific coils for this 7T system, it is necessary to carefully assess the distribution of electromagnetic (EM) fields generated by the coils and evaluate the patient/object safety during MRI pr

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Yamada, Kenichi, Junichi Yoshimura, Masaki Watanabe, and Kiyotaka Suzuki. "Application of 7 tesla magnetic resonance imaging for pediatric neurological disorders: Early clinical experience." Journal of Clinical Imaging Science 11 (December 2, 2021): 65. http://dx.doi.org/10.25259/jcis_185_2021.

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Ultra-high field magnetic resonance imaging (MRI) has been introduced for use in pediatric developmental neurology. While higher magnetic fields have certain advantages, optimized techniques with specific considerations are required to ensure rational and safe use in children and those with pediatric neurological disorders (PNDs). Here, we summarize our initial experience with clinical translational studies that utilized 7 tesla (T)-MRI in the fields of developmental neurology. T2-reversed images and three-dimensional anisotropy contrast imaging enabled the depiction of targeted pathological b

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Dou, Yan, Jinzhang Xu, Yuxia Hu, et al. "Optimization and Testing of a 1H/3He Double-Nuclear Quadrature Transmit Coil, Applying the Analytical Method at 0.06T." Journal of Medical Imaging and Health Informatics 10, no. 11 (2020): 2699–706. http://dx.doi.org/10.1166/jmihi.2020.3203.

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Application of polarized noble gas technology in lung functional magnetic resonance imaging (fMRI) has garnered attention for its unique advantages, such as high resolution and a lack of radiation exposure. This paper presents a 4-channel radio frequency (RF) coil design method for applications of an 1H/3He MRI system at the ultra-low field of 0.06T. For the complex model of the double-nuclear 1H/3He coil, the analytical optimization method (based on the theories of Biot-Savart law and PSO algorithm) and the electromagnetic (EM) field and radio frequency (RF) circuit co-simulation method was i

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Altaf, Ahmed, Muhammad Shakir, Muhammad Jawad Amin Malik, et al. "Intraoperative use of low-field magnetic resonance imaging for brain tumors: A systematic review." Surgical Neurology International 14 (October 6, 2023): 357. http://dx.doi.org/10.25259/sni_510_2023.

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Background: Low-field magnetic resonance imaging (LF-MRI) has become a valuable tool in the diagnosis of brain tumors due to its high spatial resolution and ability to acquire images in a short amount of time. However, the use of LF-MRI for intraoperative imaging during brain tumor surgeries has not been extensively studied. The aim of this systematic review is to investigate the impact of low-field intraoperative magnetic resonance imaging (LF-IMRI) on the duration of brain tumor surgery and the extent of tumor resection. Methods: A comprehensive literature search was conducted using PubMed,

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Odenbach, Robert, Niklas Thoma, Hendrik Mattern, and Michael Friebe. "Remotely controllable phantom rotation system for ultra-high field MRI to improve Cross Calibration." Current Directions in Biomedical Engineering 5, no. 1 (2019): 429–31. http://dx.doi.org/10.1515/cdbme-2019-1570538325.

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AbstractOptical tracking systems, such as the Moiré Phase Tracking system (MPT), can be used to correct motion prospectively especially during magnetic resonance imaging (MRI, MR) in neurologic application. For that an MRI safe camera is mounted in the MRI bore to detect motion by tracking a specific MPT marker, which is rigidly attached on the subject’s head. To enable prospective updates of the imaging volume´s position and orientation, and therefore to correct motion from the subject, the motion information captured from the camera need to be transformed from the camera into the MR coordina

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Jonkman, Laura E., Lazar Fleysher, Martijn D. Steenwijk, et al. "Ultra-high field MTR and qR2* differentiates subpial cortical lesions from normal-appearing gray matter in multiple sclerosis." Multiple Sclerosis Journal 22, no. 10 (2016): 1306–14. http://dx.doi.org/10.1177/1352458515620499.

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Background: Cortical gray matter (GM) demyelination is frequent and clinically relevant in multiple sclerosis (MS). Quantitative magnetic resonance imaging (qMRI) sequences such as magnetization transfer ratio (MTR) and quantitative R2* (qR2*) can capture pathological subtleties missed by conventional magnetic resonance imaging (MRI) sequences. Although differences in MTR and qR2* have been reported between lesional and non-lesional tissue, differences between lesion types or lesion types and myelin density matched normal-appearing gray matter (NAGM) have not been found or investigated. Object

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Wiet, Gregory J., Petra Schmalbrock, Kimerly Powell, and Don Stredney. "Use of Ultra-High-Resolution Data for Temporal Bone Dissection Simulation." Otolaryngology–Head and Neck Surgery 133, no. 6 (2005): 911–15. http://dx.doi.org/10.1016/j.otohns.2005.05.655.

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OBJECTIVES: For the past 5 years, our group has been developing a virtual temporal bone dissection environment for training otologic surgeons. Throughout the course of our development, a recurring challenge is the acquisition of high-resolution, multimodal, and multi-scale data sets that are used for the visual as well as haptic (sense of touch) display. This study presents several new techniques in temporal bone imaging and their use as data for surgical simulation. METHODS: At our institution (OSU), we are fortunate to have a high-field (8 Tesla) magnetic resonance imaging (MRI) research mag

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Du, Hui, Qiyue Wang, Zeyu Liang, Qilong Li, Fangyuan Li, and Daishun Ling. "Designed Fabrication of Magnetic Nanoprobes for Ultra-High-Field Magnetic Resonance Imaging." Nanoscale, 2022. http://dx.doi.org/10.1039/d2nr04979a.

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Ultra-high-field magnetic resonance imaging (UHF-MRI) has been attracting tremendous attention in biomedical imaging owing to its high signal-to-noise ratio, superior spatial resolution, and fast imaging speed. However, at UHF-MRI, there...

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Liang, Zeyu, Lin Xiao, Qiyue Wang, et al. "Ligand‐Mediated Magnetism‐Conversion Nanoprobes for Activatable Ultra‐High Field Magnetic Resonance Imaging." Angewandte Chemie International Edition, January 11, 2024. http://dx.doi.org/10.1002/anie.202318948.

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Ultra‐high field (UHF) magnetic resonance imaging (MRI) has emerged as a focal point of interest in the field of cancer diagnosis. Despite the ability of current paramagnetic or superparamagnetic smart MRI contrast agents to selectively enhance tumor signals in low‐field MRI, their effectiveness at UHF remains inadequate due to inherent magnetism. Here, we report a ligand‐mediated magnetism‐conversion nanoprobe (MCNP) composed of 3‐mercaptopropionic acid ligand‐coated silver‐gadolinium bimetallic nanoparticles. The MCNP exhibits a pH‐dependent magnetism conversion from ferromagnetism to diamag

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Liang, Zeyu, Lin Xiao, Qiyue Wang, et al. "Ligand‐Mediated Magnetism‐Conversion Nanoprobes for Activatable Ultra‐High Field Magnetic Resonance Imaging." Angewandte Chemie, January 11, 2024. http://dx.doi.org/10.1002/ange.202318948.

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Ultra‐high field (UHF) magnetic resonance imaging (MRI) has emerged as a focal point of interest in the field of cancer diagnosis. Despite the ability of current paramagnetic or superparamagnetic smart MRI contrast agents to selectively enhance tumor signals in low‐field MRI, their effectiveness at UHF remains inadequate due to inherent magnetism. Here, we report a ligand‐mediated magnetism‐conversion nanoprobe (MCNP) composed of 3‐mercaptopropionic acid ligand‐coated silver‐gadolinium bimetallic nanoparticles. The MCNP exhibits a pH‐dependent magnetism conversion from ferromagnetism to diamag

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Liang, Zeyu, Qiyue Wang, Hongwei Liao, et al. "Artificially engineered antiferromagnetic nanoprobes for ultra-sensitive histopathological level magnetic resonance imaging." Nature Communications 12, no. 1 (2021). http://dx.doi.org/10.1038/s41467-021-24055-2.

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AbstractHistopathological level imaging in a non-invasive manner is important for clinical diagnosis, which has been a tremendous challenge for current imaging modalities. Recent development of ultra-high-field (UHF) magnetic resonance imaging (MRI) represents a large step toward this goal. Nevertheless, there is a lack of proper contrast agents that can provide superior imaging sensitivity at UHF for disease detection, because conventional contrast agents generally induce T2 decaying effects that are too strong and thus limit the imaging performance. Herein, by rationally engineering the size

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Shaffer, Annabelle, Susanna S. Kwok, Anant Naik, et al. "Ultra-High-Field MRI in the Diagnosis and Management of Gliomas: A Systematic Review." Frontiers in Neurology 13 (April 5, 2022). http://dx.doi.org/10.3389/fneur.2022.857825.

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Importance:Gliomas, tumors of the central nervous system, are classically diagnosed through invasive surgical biopsy and subsequent histopathological study. Innovations in ultra-high field (UHF) imaging, namely 7-Tesla magnetic resonance imaging (7T MRI) are advancing preoperative tumor grading, visualization of intratumoral structures, and appreciation of small brain structures and lesions.ObjectiveSummarize current innovative uses of UHF imaging techniques in glioma diagnostics and treatment.MethodsA systematic review in accordance with PRISMA guidelines was performed utilizing PubMed. Case

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Schreiber, Laura M., David Lohr, Steffen Baltes, et al. "Ultra-high field cardiac MRI in large animals and humans for translational cardiovascular research." Frontiers in Cardiovascular Medicine 10 (May 15, 2023). http://dx.doi.org/10.3389/fcvm.2023.1068390.

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A key step in translational cardiovascular research is the use of large animal models to better understand normal and abnormal physiology, to test drugs or interventions, or to perform studies which would be considered unethical in human subjects. Ultrahigh field magnetic resonance imaging (UHF-MRI) at 7 T field strength is becoming increasingly available for imaging of the heart and, when compared to clinically established field strengths, promises better image quality and image information content, more precise functional analysis, potentially new image contrasts, and as all in-vivo imaging

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Du, Hui, Qiyue Wang, Bo Zhang, et al. "Structural Defect‐Enabled Magnetic Neutrality Nanoprobes for Ultra‐High‐Field Magnetic Resonance Imaging of Isolated Tumor Cells In Vivo." Advanced Materials, May 13, 2024. http://dx.doi.org/10.1002/adma.202401538.

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AbstractThe identification of metastasis “seeds”, isolated tumor cells (ITCs), is of paramount importance for the prognosis and tailored treatment of metastatic diseases. The conventional approach to clinical ITCs diagnosis through invasive biopsies is encumbered by the inherent risks of overdiagnosis and overtreatment. This underscores the pressing need for non‐invasive ITCs detection methods that provide histopathological‐level insights. Recent advancements in ultra‐high‐field (UHF) magnetic resonance imaging (MRI) have ignited hope for the revelation of minute lesions, including the elusive

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Lemmens, Marie-Julie D. K., R. H. G. J. van Lanen, D. Uher, et al. "Ex vivo ultra-high field magnetic resonance imaging of human epileptogenic specimens from primarily the temporal lobe: A systematic review." Neuroradiology, March 8, 2025. https://doi.org/10.1007/s00234-024-03474-0.

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Abstract Purpose Magnetic resonance imaging (MRI) is the preferred diagnostic tool for the detection of structural cerebral lesions in patients with epilepsy. Ultra-high field (UHF) MRI with field strengths ≥7 Tesla has been reported to improve the visualization and delineation of epileptogenic lesions. The use of ex vivo UHF MRI may expand our knowledge on the detection and detailed micromorphology of subtle epileptogenic lesions by bridging the gap between in vivo MRI and histopathology. Methods A systematic review of available literature was conducted following PRISMA guidelines. A descript

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