Academic literature on the topic 'Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)'

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Journal articles on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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Chen, Wen-Ling, Tzu-Fang Hsu, and Chia-Yang Chen. "Performance Liquid Chromatography/Tandem Mass Spectrometry." Journal of AOAC INTERNATIONAL 94, no. 3 (2011): 872–77. http://dx.doi.org/10.1093/jaoac/94.3.872.

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Abstract A sensitive method was developed using ultra-high-performance liquid chromatography (UHPLC)/MS/MS with positive electrospray ionization for determining aflatoxin M1 (AFM1) in milk and milk powder. A 50 mL quantity of low-fat liquid milk containing 100 ng/L AFM1 was prepared using immunoaffinity columns with a mean recovery rate of 79% (n = 3). UHPLC columns (BEH C18, BEH HILIC, and HSS T3) greatly reduced the chromatographic time and lowered the instrumental detection limits (IDLs) 16 to 58 times compared to an HPLC column (Betabasic C18). The HSS T3 column was chosen because it provi
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Khan, Hamid. "UHPLC-MS/MS Technique: Applications in Analytical Chemistry." Asian Journal of Chemistry 36, no. 4 (2024): 766–78. http://dx.doi.org/10.14233/ajchem.2024.31383.

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The ultra-high performance liquid chromatography-mass spectrometry/mass spectrometry (UHPLC-MS/MS) is becoming most advanced technique used for analysis of wide range of compounds in analytical chemistry. This technique has been effectively utilized for identifying and quantitatively determining substances in several pharmaceutical analysis fields. The UHPLC technique offers superior sensitivity, selectivity and peak shape in comparison to the conventional HPLC technique. The UHPLC coupled with various mass spectrometers gives accurate mass fragmentations which is ultimately helpful in structu
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Faccin, Henrique, Roberta Fabricio Loose, Carine Viana, Osmar A. Lameira, and Leandro Machado de Carvalho. "Determination of phenolic compounds in extracts of Amazonian medicinal plants by liquid chromatography-electrospray tandem mass spectrometry." Analytical Methods 9, no. 7 (2017): 1141–51. http://dx.doi.org/10.1039/c6ay02937j.

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A method for the separation, identification and quantification of 24 phenolic compounds using ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was developed and validated.
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Bayer, O. V., O. V. Kaminska, O. V. Bondarets, et al. "Evaluation of Ultra-High-Performance Liquid Chromatography (HPLC) Tandem Mass Spectrometry for Determination of Avermectin Residues in Milk." Ukrainian Journal of Ecology 9, no. 4 (2019): 521–26. http://dx.doi.org/10.15421/2019_784.

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The study was conducted to evaluate the applicability of ultra high-performance liquid chromatography - tandem mass spectrometry method (UHPLC-MS/MS), establish the MS/MS detection parameters and determine the validation characteristics for the analysis of residual content of avermectins in milk. The UHPLC-MS/MS method has proved to be accurate, practical and universal. This was confirmed by Decision limit (CCα) data: abamectin - 12.56 μg/kg, doramectin - 17.74 μg/kg, eprinomectin - 24.02 μg/kg, ivermectin - 12.53 μg/kg, moxidectin - 44.69 μg/kg, recovery is 88.7-110%. The data obtained for as
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Wang, Haijun, Qiao Zhang, Xiaolin Li, et al. "Simultaneous analysis of multi-class antibiotics in bottled water using large-volume direct-injection LC-MS/MS." RSC Advances 15, no. 21 (2025): 16973–82. https://doi.org/10.1039/d5ra01764e.

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A large-volume direct-injection (LVDI) method was developed and validated for the simultaneous analysis of 69 antibiotics in bottled water using ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).
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Nie, Xu-Heng, and Hua-Chun Guo. "An ultra-high-performance liquid chromatography-triple quadrupole mass spectrometry method for the detection of steroidal glycoalkaloids in potato samples." Analytical Methods 9, no. 47 (2017): 6613–21. http://dx.doi.org/10.1039/c7ay02244a.

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An ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method has been optimized and validated to simultaneously monitor steroidal glycoalkaloids (SGAs), α-chaconine and α-solanine, in potato samples stored under natural indoor conditions in Kunming.
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Ahmad, Niyaz, Khalid Ansari, Mariam K. Alamoudi, et al. "A novel mucoadhesive paliperidone-nanoemulsion developed using the ultrasonication method in the treatment of schizophrenia." RSC Advances 14, no. 33 (2024): 23952–72. http://dx.doi.org/10.1039/d4ra04624b.

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Enhancing the brain bioavailability of paliperidone by developing a novel mucoadhesive-CS-coated-PLP-NE and examining the quantity of PLP by developing a novel method of ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) in schizophrenic rat brain treatment.
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Václavík, L., J. Ovesná, L. Kučera, J. Hodek, K. Demnerová, and J. Hajšlová. "Application of ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) metabolomic fingerprinting to characterise GM and conventional maize varieties." Czech Journal of Food Sciences 31, No. 4 (2013): 368–75. http://dx.doi.org/10.17221/177/2013-cjfs.

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The feasibility of metabolomic fingerprinting approach based on ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UHPLC-QTOFMS) was studied to assess its ability to discriminate between maize varieties, and to show the associations between them on the metabolomic level. The non-targeted metabolomic analysis was applied to assess the variability within two varieties grown under different environmental conditions and to characterise the association within a sample set comprising both conventional and transgenic (MON-ØØ81Ø-6
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Gao, Hongxue, Zhiqiang Liu, Fengrui Song, Junpeng Xing, Zhong Zheng, and Shu Liu. "A Strategy for Identification and Structural Characterization of Compounds from Plantago asiatica L. by Liquid Chromatography-Mass Spectrometry Combined with Ion Mobility Spectrometry." Molecules 27, no. 13 (2022): 4302. http://dx.doi.org/10.3390/molecules27134302.

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Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging. In this study, an integrated strategy based on three-dimensional separation including AB-8 macroporous resin column chromatography, ultra-high performance liquid chromatography–quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF MS), and ultra-high performance liquid chromatography-mass spectrometry with ion-mobility spectrometry (UHPLC-IM-MS) was established and used to separate and identify the structures o
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Mi, Yueguang, Wandi Hu, Weiwei Li, et al. "Systematic Qualitative and Quantitative Analyses of Wenxin Granule via Ultra-High Performance Liquid Chromatography Coupled with Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry and Triple Quadrupole–Linear Ion Trap Mass Spectrometry." Molecules 27, no. 11 (2022): 3647. http://dx.doi.org/10.3390/molecules27113647.

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Wenxin granule (WXG) is a popular traditional Chinese medicine (TCM) preparation for the treatment of arrhythmia disease. Potent analytical technologies are needed to elucidate its chemical composition and assess the quality differences among multibatch samples. In this work, both a multicomponent characterization and quantitative assay of WXG were conducted using two liquid chromatography–mass spectrometry (LC-MS) approaches. An ultra-high performance liquid chromatography–ion mobility quadrupole time-of-flight mass spectrometry (UHPLC/IM-QTOF-MS) approach combined with intelligent peak annot
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Dissertations / Theses on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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Oshita, Daniele 1981. "Desenvolvimento e validação de método analítico para determinação de multirresíduos de agrotóxicos em morango por LC-MS/MS e comparação com UHPLC." [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/250530.

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Orientador: Isabel Cristina Sales Fontes Jardim<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química<br>Made available in DSpace on 2018-08-24T08:24:02Z (GMT). No. of bitstreams: 1 Oshita_Daniele_D.pdf: 4645263 bytes, checksum: 6628dba7b8449d1cf1f86afa3dcae9e2 (MD5) Previous issue date: 2013<br>Resumo: Este trabalho envolve o desenvolvimento, a otimização e a validação de um método analítico para determinação de multirresíduos de agrotóxicos em amostras de morango, por cromatografia líquida acoplada à espectrometria de massas sequencial (LC-MS/MS). No preparo de amos
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Lopez, Begoña Gimenez-Cassina 1984. "Análise da composição de amostras de própolis vermelha do Brasil por espectrometria de massas com ionização por eletrospray e cromatografia líquida de ultra-eficiência (UPLC-ESI-MS) e avaliação da atividade antioxidante e antimicrobiana = Analysis of the composition of samples of red brazilian propolis by mass spectrometry with electrospray ionization and ultra high performance liquid chromatography (UPLC-ESI-MS) and evaluation of the antioxidant and antimicrobial activity." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316101.

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Orientador: Alexandra Christine Helena Frankland Sawaya<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-24T09:51:06Z (GMT). No. of bitstreams: 1 Lopez_BegonaGimenez-Cassina_M.pdf: 5145110 bytes, checksum: e91f0a5d069796983ac9064ccc7af78c (MD5) Previous issue date: 2014<br>Resumo: A palavra própolis tem origem Grega: pro significa em defensa de, e polis significa comunidade. A própolis é usada pelas abelhas para fortalecer as paredes da colmeia e para cobrir as paredes internas e por devido a sua atividade antimicrobi
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Kozáková, Soňa. "Obsah adaptogenů v rostlině Schizandra chinensis." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2013. http://www.nusl.cz/ntk/nusl-216982.

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This thesis deals with the content of adaptogens in vegetable Schizandra chinensis. The theoretical part deals with the plant Schisandra chinensis, its occurrence, characteristics, uses and cultivation. Location of plants Schisandra chinensis are classified according to Köppen climate classification and compared with the climate in the Czech Republic, due to possible prediction of growing plants in the country. Further are described adaptogens (bioactive substances) contained in this plant and to methods for their extraction and analysis. The experimental part of the thesis deals with the iden
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Miranda, Luís Felippe Cabral. "Desenvolvimento de uma fase extratora com polímeros de impressão molecular para extração em fase sólida de Venlafaxina, O-desmetilvenlafaxina e N-desmetilvenlafaxina em amostras de plasmas e análises por cromatografia líquida de ultra eficiência acoplada à espectometria de massas em tandem (UPLC-MS/MS)." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-15052015-122818/.

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A venlafaxina (VEN), em razão de sua eficácia e brandos efeitos adversos, tem sido um dos antidepressivos mais prescritos no tratamento da depressão e ansiedade. Neste trabalho, um método analítico empregando as técnicas MISPE miniaturizada e cromatografia líquida acoplada à espectrometria de massas em Tandem, foi utilizado para a determinação de VEN e seus principais metabólitos em amostras de plasma para fins de monitorização terapêutica. A fase MIP foi sintetizada via polimerização radicalar por precipitação, fazendo uso de VEN (molécula molde), ácido metacrílico (monômero funcional), etile
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Pouech, Charlene. "Développement de méthodologies analytiques pour l'étude de la migration depuis des contenants en matière plastique prévus pour des applications pharmaceutiques vers des solutions aqueuses et des fluides biologiques." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10118.

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Ameline, Alice. "Aspects analytiques, cliniques et médico-judiciaires des nouvelles substances psychoactives." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAJ018/document.

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En raison de la diffusion incontrôlée sur le e-commerce, la sécurité et l’alternative légale aux stupéfiants habituels, les nouvelles substances psychoactives (NPS), d’apparition récente (2008), sont au cœur des phénomènes récents d’addiction et de décès mal expliqués. Au-delà des différents défis dans nos sociétés (prévention, législation), la capacité d’identifier les NPS dans des échantillons biologiques pour caractériser leur utilisation, présente de nombreux challenges analytiques. L’objectif principal de cette thèse a été de collecter des échantillons biologiques (sang, urine, cheveux) p
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Fohet, Loélia. "Dissémination et vieillissement des particules d'usure de pneumatiques : impacts environnementaux." Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2023. http://www.theses.fr/2023UCFA0056.

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Les particules d'usure de pneumatiques (Tire and Road Wear Particles - TRWP) sont des particules issues de l'abrasion des pneus sur la route lors de leur roulage. Elles sont de plus en plus étudiées du fait de leur impact encore mal connu sur l'environnement, notamment par les molécules qu'elles peuvent relarguer. En effet, la composition de la bande de roulement, dont elles proviennent, est complexe et constitue un cocktail de produits chimiques. Lors de ces travaux de thèse, des vieillissements de ces particules ont été réalisés en conditions accélérées (photochimique et thermique) et nature
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Alabbas, Alhumaidi. "Reversed-phase Ion-Pairing Ultra Performance Liquid Chromatography-Mass Spectrometry in Characterization of Glycosaminoglycans." VCU Scholars Compass, 2014. http://scholarscompass.vcu.edu/etd/3547.

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Glycosaminoglycans (GAGs) are a family of linear bio-polysaccharides, which are heterogeneously modified with negatively charged sulfate and carboxylate groups. They are located on every cell surface, extracellular matrix or intracellular space in the body. GAGs are composed of alternating units of an amino sugars (glucosamine or galactosamine) and hexuronic acid/hexose (iduronic acid, glucoronic acid/ or galactose), which are linked by glycosidic bonds with different geometries. In recent years, GAGs have attracted considerable interest. GAGs play vital roles in fundamental biological process
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Benson, Andrew James. "High-performance liquid chromatography (HPLC) and high-performance liquid chromatography mass spectrometry (HPLC/MS) for the analysis of date rape drugs." FIU Digital Commons, 2002. http://digitalcommons.fiu.edu/etd/1602.

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The drugs studied in this work have been reportedly used to commit drug-facilitated sexual assault (DFSA), commonly known as "date rape". Detection of the drugs was performed using high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and identified with high performance-liquid chromatography mass spectrometry (HPLC/MS) using selected ion monitoring (SIM). The objective of this study was to develop a single HPLC method for the simultaneous detection, identification and quantitation of these drugs. The following drugs were simultaneously analyzed: Gamma-hydroxybutyrate (GH
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Ansong, Godfred. "Analysis of plant polyphenols by high performance liquid chromatography/mass spectrometry and protein binding." Oxford, Ohio : Miami University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1083081905.

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Books on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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McMaster, Marvin. LC/MS. John Wiley & Sons, Ltd., 2005.

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Oehme, Michael. Pratical introduction to GC-MS analysis with quadrupoles. Edited by Dünges Wolfgang. Heidelberg, 1999.

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Kromidas, Stavros. HPLC-MS Handbook for Practitioners. Wiley & Sons, Incorporated, John, 2017.

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Kromidas, Stavros. HPLC-MS Handbook for Practitioners. Wiley & Sons, Limited, John, 2017.

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Kromidas, Stavros. HPLC-MS Handbook for Practitioners. Wiley & Sons, Incorporated, John, 2017.

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Kromidas, Stavros. HPLC-MS Handbook for Practitioners. Wiley & Sons, Incorporated, John, 2017.

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HPLC-MS Handbook for Practitioners. Wiley-VCH Verlag GmbH, 2017.

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Book chapters on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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Herath, I., J. Bundschuh, and P. Bhattacharya. "Ultra-High Performance Liquid Chromatography (UHPLC) hyphenated to Inductively Coupled Plasma Mass Spectrometry (ICP-MS) for fast analysis of arsenic species in environmental and biological media." In Arsenic in the Environment: Bridging Science to Practice for Sustainable Development As2021. CRC Press, 2024. http://dx.doi.org/10.1201/9781003317395-66.

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Hansen, Steen Honoré, and Leon Reubsaet. "High-Performance Liquid Chromatography (HPLC) and High-Performance Liquid Chromatography-Mass Spectrometry (LC-MS)." In Bioanalysis of Pharmaceuticals. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118716830.ch7.

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Munar, Ada, Clint Frazee, Bridgette Jones, and Uttam Garg. "Cetirizine Quantification by High-Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3252-8_13.

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Bielawski, Jacek, Jason S. Pierce, Justin Snider, Barbara Rembiesa, Zdzislaw M. Szulc, and Alicja Bielawska. "Sphingolipid Analysis by High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS)." In Advances in Experimental Medicine and Biology. Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6741-1_3.

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Wilson, Ian D. "High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS)-Based Drug Metabolite Profiling." In Methods in Molecular Biology. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-61737-985-7_10.

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Hobert, Judith A., Stephen A. Brose, and Marzia Pasquali. "Quantitation of Butyrylcarnitine, Isobutyrylcarnitine, and Glutarylcarnitine in Urine Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)." In Clinical Applications of Mass Spectrometry in Biomolecular Analysis. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2565-1_8.

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Vicente, Faye B., Gina Vespa, Alan Miller, and Shannon Haymond. "Quantification of Iohexol in Serum by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3252-8_20.

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Rodell, Rebecca, Ning Tsao, Adit Ganguly, and Nima Mosammaparast. "Use of High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) to Quantify Modified Nucleosides." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2063-2_8.

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Piri-Moghadam, Hamed, Alan Miller, Debra Pronger, et al. "Quantification of Branched-Chain Amino Acids in Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)." In Clinical Applications of Mass Spectrometry in Biomolecular Analysis. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2565-1_7.

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Donaldson, Keri J., and Leslie M. Shaw. "Quantitation of Tacrolimus in Whole Blood Using High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS-MS)." In Methods in Molecular Biology. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60761-459-3_47.

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Conference papers on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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Devina, Kezia Elian, Dono Indarto, and Tri Nugraha Susilawati. "Identification of Quercetin and Chrysin in Banana Peel Extract Using High Performance Liquid Chromatography and Liquid Chromatography Mass Spectrometer for Obesity Treatment." In 8th International Conference on Advanced Material for Better Future. Trans Tech Publications Ltd, 2025. https://doi.org/10.4028/p-6iz2xi.

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Pancreatic lipase plays an important role in converting triglyceride into long-chain fatty acids and glycerol, then becomes a therapeutic target for obesity treatment. Quercetin and chrysin are able to inhibit pancreatic lipase, which is potentially developed for obesity treatment. This study aimed to identify quercetin and chrysin derived from the methanol extract of raja and kepok banana peels using High Performance Liquid Chromatography (HPLC) and Liquid Chromatography Mass Spectrometer (LC-MS) for the development of obesity treatment. Raja and kepok banana peels were purchased from a fruit
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Jackson, Tracey, and Jonathan Vargas. "Selective Loss of Bulk Corrosion Inhibitor Species When Exposed to Glass, Plastic, and Steel." In CORROSION 2020. NACE International, 2020. https://doi.org/10.5006/c2020-14999.

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Abstract Despite the widespread use of corrosion inhibitors (CIs) in the oil and gas industry much of their complex aggregation and adsorption behavior is still very poorly understood. CIs are surface active species meaning that when they are injected into aqueous solutions they naturally aggregate and migrate to gas-liquid, liquid-liquid, and solid-liquid interfaces. A better understanding of each CI component and how it adsorbs when exposed to various surfaces could lead to improved CI design, higher performance at lower dosages, as well as improved methods for residual detection. This paper
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Barker, Richard, Richard C. Woollam, and William H. Durnie. "Implications of Physical and Chemical Environment on the Distribution of Corrosion Inhibitor Surfactant Components and Mixtures." In CONFERENCE 2025. AMPP, 2025. https://doi.org/10.5006/c2025-00436.

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Abstract Corrosion inhibitors are a proven cost-effective method for internal corrosion protection of carbon steel piping in the presence of CO2-containing brines. The appropriate selection, deployment and performance monitoring are all essential elements ensuring successful application. However, despite many years of use within the oil and gas industry, a clear understanding of the impact of the physical chemistry of surfactants and surfactant mixtures still eludes the industry, and chemical law is often replaced with oilfield lore. In this work, the effect of brine salinity (0.1, 1 and 10 wt
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Blebea, Nicoleta Mirela, and Simona Negreș. "METHODS FOR QUANTIFICATION OF THE MAIN CANNABINOIDS IN CBD OIL." In GEOLINKS Conference Proceedings. Saima Consult Ltd, 2021. http://dx.doi.org/10.32008/geolinks2021/b1/v3/13.

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Cannabidiol (CBD) is an alkaloid present in Cannabis sativa, together with tetrahydrocannabinol (THC) and more than 120 other substances belonging to a group of compounds named cannabinoids. Due to the continuous increased usage of CBD oils, it became necessary to be developed efficient methods for the identification of its compounds and especially for the characterization of the cannabinoids from the commercial specimens. Cannabinoids may be detected by many and different analytical methods, including immunoassays (EMIT®, Elisa, fluorescent polarization, radioimmunotest), techniques of flat c
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Hajslova, Jana, Enrico Valli, Klara Navratilova, and Tullia Gallina Toschi. "Metabolic fingerprinting strategies for authentication challenge: EVOO adulterated by soft deodorized olive oil." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/qepz3229.

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Extra virgin olive oil (EVOO) is a high value commodity that might be subject of various fraudulent practices. One of them, addition of lower grade, soft-deodorized olive oil to EVOO has recently become of concern, as such adulterant detection is not an easy task. In this study, aqueous methanolic extracts of a unique set of authentic EVOOs, soft-deodorized oils and their admixtures obtained within the OLEUM EU project (http://www.oleumproject.eu/) were investigated. Using ultra-high performance liquid chromatography coupled to hybrid quadrupole time-of-flight high-resolution tandem mass spect
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CODREANU, Andreea-Miruna, Valentina-Andreea CĂLMUC, Adelina Ștefania MILEA, Alin DÎRȚU, Cătălina ITICESCU, and Puiu Lucian GEORGESCU. "UHPLC-HRMS analysis of pfas in freshwater from the lower Danube area." In International congress "Research-Innovation-Inovative Entreneurship". Ion Creangă Pedagogical State University, 2024. https://doi.org/10.46727/c.13-14-10-2023.p252-253.

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Per- and polyfluoroalkyl substances (PFAS) are widely used, long lasting synthetic chemicals, components of which break down very slowly over time. This study presents the qualitative analysis of the most common 18 PFAS in freshwater samples using a Ultra-High-Performance Liquid Chromatography – High Resolution Mass Spectrometry (UHPLC-HRMS) analytical technique. The samples were collected in spring and summer of 2023 from 7 stations along the Lower Danube River. Prior to the analysis, the water samples were submitted to automated solid phase extraction (SPE). The UHPLC-HRMS system provided ex
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Ow, Hooisweng, Sehoon Chang, Gawain Thomas, Wei Wang, Afnan A. Mashat, and Hussein Shateeb. "Automatable High Sensitivity Tracer Detection: Toward Tracer Data Enriched Production Management of Hydrocarbon Reservoirs." In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/206338-ms.

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Abstract The development of automatable high sensitivity analytical methods for tracer detection has been one of the most central challenges to realize ubiquitous full-field tracer deployment to study reservoirs with many cross-communicating injector and producer wells. Herein we report a tracer analysis approach, inspired by strategies commonly utilized in the biotechnology industry, that directly addresses key limitations in process throughput, detection sensitivity and automation potential of state-of-the-art technologies. A two-dimensional high performance liquid chromatography (2D-HPLC) m
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de Vries, J. X., R. Raedsch, A. Stiehl, U. Voelker, I. Walter-Sack, and E. Weber. "EVIDENCE FOR BIIIARY EXCRETION OF PHENPROCOUMON AND ITS METABOLITES IN HUMANS; IDENTIFICATION BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643272.

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Recently it has been shown that in man the oral couma-rin anticoagulant phenprocoumon is eliminated up to 60-70 % in urine and 30-40 % in faeces; in urine phenprocoumon (PH) and its metabolites 7-hydroxy-(7-OH),6-hydroxy-(6-OH) and 4'-hydroxy-(4'-OH) phenprocoumon are present mainly as conjugates. No data so far were available on the biliary excretion of these compounds.We examined bile obtained from four in-patients during PH treatment; bile samples were aspirated in the duodenum at the papilla during routine diagnostic endoscopy and immediately deep frozen before analysis. Samples were extra
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Guo, Zhongxian, Qiantao Cai, and Zhaoguang Yang. "Determination of Water-Soluble Organophosphorus Herbicides by Ion Chromatography With Inductively Coupled Plasma Mass Spectrometry Detection." In 1st Water Quality, Drought, Human Health and Engineering Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/water2006-20024.

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There is a high risk for human exposure to organophosphorus pesticides through contaminated drinking water. Glyphosate, glufosinate, fosamine and ethephon are among the water-soluble herbicides used currently. Sensitive and rapid analytical methodologies are critical for evaluating their residuals in a broad variety of samples, including environmental waters. However, challenges arise from the inherent chemical properties of the herbicides: strong polarity, high solubility in water, insolubility in organic solvent (except ethephon), absence of chromophore or fluorophore in their molecular stru
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Holcapek, Michal. "Potential of lipid class separation- mass spectrometry approaches for high-throughput lipidomic quantitation." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/djkv2622.

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The coupling of liquid-phase separation techniques and mass spectrometry (MS) is the prevailing analytical strategy in lipidomic analysis [1]. Two basic chromatographic approaches are available, lipid class separation and lipid species separation. The lipid class separation is represented by hydrophilic liquid chromatography (HILIC) and ultrahigh-performance supercritical fluid chromatography (UHPSFC) and offers advantages for high-throughput quantitation due to the coelution of lipid class internal standards and analytes from the same class [2]. Multiple lipid classes from phospholipid, sphin
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Reports on the topic "Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS)"

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แก้วกิติณรงค์, กมล, วีรวัฒน์ มโนสุทธิ, โอภาส พุทธเจริญ та ін. การศึกษาทางด้านเภสัชจลนศาสตร์ ประสิทธิผล ความปลอดภัย และความทนทานต่อยาโลพินาเวียร์/ยาริโทนาเวียร์ขนาดมาตรฐานร่วมกับยาไรฟาบูตินขนาด 150 มิลลิกรัมต่อวัน (ขนาดมาตรฐาน) หรือขนาด 300 มิลลิกรัม 3 ครั้งต่อสัปดาห์ (ขนาดต่ำ)ในผู้ป่วยติดเชื้อเอชไอวีที่เป็นวัณโรค. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2018. https://doi.org/10.58837/chula.res.2018.28.

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บทนำ: ยาไรแฟมปิซินสามารถกระตุ้นเอนไซม์ไซโตโครม P450 ได้ซึ่งทำให้ระดับยาโลพินาเวียร์ลดลงอย่างมากเมื่อให้ยาคู่กันจึงมีคำแนะนำให้ใช้ยาไรฟาบูตินแทนไรแฟมปิซินเมื่อต้องใช้คู่กับยาโลพินาเวียร์ อย่างไรก็ตามขนาดยาไรฟาบูตินที่แนะนำอาจไม่เพียงพอ จุดประสงค์หลักของการศึกษานี้คือเพื่อเปรียบเทียบค่าเภสัชจลนศาสตร์ของยาไรฟาบูตินขนาด 150 มก. วันละครั้งกับ 300 มก. สามครั้งต่อสัปดาห์ เมื่อให้คู่กับยาโลพินาเวียร์/ริโทนาเวียร์ขนาด 400/100 มก. วันละสองครั้ง ในผู้ป่วยติดเชื้อ HIV ร่วมกับวัณโรค วิธีการวิจัย: การศึกษานี้เป็นการศึกษาแบบสุ่มซึ่งไม่ปกปิดทั้งผู้วิจัยและผู้ร่วมการศึกษาโดยแบ่งผู้ป่วยเป็น 2 กลุ่ม เป็นการศึกษา
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Crouch, Rebecca, Jared Smith, Bobbi Stromer, et al. Methods for simultaneous determination of legacy and insensitive munition (IM) constituents in aqueous, soil/sediment, and tissue matrices. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41720.

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Currently, no standard method exists for analyzing insensitive munition (IM) compounds in environmental matrices, with or without concurrent legacy munition compounds, resulting in potentially inaccurate determinations. The primary objective of this work was to develop new methods of extraction, pre-concentration, and analytical separation/quantitation of 17 legacy munition compounds along with several additional IM compounds, IM breakdown products, and other munition compounds that are not currently included in U.S. Environmental Protection Agency (EPA) Method 8330B. Analytical methods were d
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Crouch, Rebecca, Jared Smith, Bobbi Stromer, et al. Preparative, extraction, and analytical methods for simultaneous determination of legacy and insensitive munition (IM) constituents in aqueous, soil or sediment, and tissue matrices. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41480.

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No standard method exists for determining levels of insensitive munition (IM) compounds in environmental matrices. This project resulted in new methods of extraction, analytical separation and quantitation of 17 legacy and 7 IM compounds, daughter products of IM, and other munition compounds absent from USEPA Method 8330B. Extraction methods were developed for aqueous (direct-injection and solid-phase extraction [SPE]), soil, sediment, and tissue samples using laboratory-spiked samples. Aqueous methods were tested on 5 water sources, with 23 of 24 compounds recovered within DoD QSM Ver5.2 limi
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