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Journal articles on the topic 'Under-Eye Hydration'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Naina, Bhargava* Rachana Akhand Giri Harshvardhan Dangi. "Revitalizing Under- Eye Hydrogel Patches: Development and Assessment." International Journal of Pharmaceutical Sciences 2, no. 8 (2024): 2487–93. https://doi.org/10.5281/zenodo.13176042.

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Under-eye gel patches are used as a cosmetic as well as a cosmeceutical formulation for their targeted delivery of active ingredients to the delicate under-eye area. This research focuses on the development and assessment of under-eye hydrogel patches aimed at enhancing skin hydration, reducing fine lines, dark circles, pigmentation and improving overall skin appearance as well as provide a soothing and cooling sensation by utilizing the hydration-retaining power of hydrogels. The study begins with the formulation of gel patches using various polymers and bioactive compounds known for their mo

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Naina, Bhargava* Rachana Akhand Giri Harshvardhan Dangi. "Revitalizing Under- Eye Hydrogel Patches: Development and Assessment." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 1598–604. https://doi.org/10.5281/zenodo.12793568.

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Under-eye gel patches are used as a cosmetic as well as a cosmeceutical formulation for their targeted delivery of active ingredients to the delicate under-eye area. This research focuses on the development and assessment of under-eye hydrogel patches aimed at enhancing skin hydration, reducing fine lines, dark circles, pigmentation and improving overall skin appearance as well as provide a soothing and cooling sensation by utilizing the hydration-retaining power of hydrogels. The study begins with the formulation of gel patches using various polymers and bioactiv

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Sejal, Telang* Irshad Ahmad Aishwarya Shrirao Vaibhavi Shenmare Sakshi Rewatkar. "Formulation And Evaluation of Herbal Eye Patches for Under-Eye Hydration and Dark Circle Reduction." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1810–19. https://doi.org/10.5281/zenodo.15385673.

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The study aims at creating herbal eye patches that will aid in enhancing under-eye hydration and reducing dark circles. By the application of natural ingredients such as potato peel powder, licorice extract, aloe vera gel, Glycerin, and rose water, the study places high emphasis on the medicinal properties of these ingredients in addressing typical cosmetic problems involving thin skin around the eyes. The strategy involved the fabrication of cotton pads and gelatin-molded eye patches, and their subsequent analysis to assess their physical properties, stability, and efficacy. Results indicated

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Shubham, Dongare* Kaushal Sonare Harsh Suroshe Pratiksha Sonawane Rajanikant Kakade. "Formulation And Evaluation of Herbal Eye Patches for Under-Eye Hydration and Dark Circle Reduction." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1890–900. https://doi.org/10.5281/zenodo.15387382.

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The human emotions are complex part of every individual.The everyday life is much more stress full and in the today's era due to he lack of career opportunities, relationships, rapidly changing lifestyle and many more reasons.the most of the persons have psychiatry disorder like depression, anxiety, discomfort. This are the disorder which are characterized with the human emotions regulation.The hormones are the main components of body which induce the emotions and change the Mood of every individual person.The hormones that characterize the emotions are cortisol, serotonin, dopamine, testoster

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Hu, Fan. "Deciphering the Dynamics of Facial Skin Aging and the Efficacy of Anti-Aging Eye Cream Through In Vivo Two-Photon Microscopy." Clinical Medical Reviews and Reports 6, no. 2 (2024): 01–12. https://doi.org/10.31579/2690-8794/204.

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Background: Skin aging is a multifactorial process influenced by genetic and environmental factors, manifesting prominently on the face. Variations in aging effects across facial areas necessitate advanced imaging for detailed assessment. Materials and Methods: We utilized a portable handheld two-photon microscope (TPM) for in vivo exploration of skin aging alterations in the periocular and cheek areas of a Chinese female population. This study included 107 healthy volunteers, aged between 18 to 60 years, categorized into four age intervals. Our research extended to a clinical trial to evaluat

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Lee, Soo Jung, and Donghun Lee. "A Case of Paralytic Strabismus after a Snake Bite on the Toe." Annals of Optometry and Contact Lens 22, no. 3 (2023): 120–23. http://dx.doi.org/10.52725/aocl.2023.22.3.120.

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Purpose: To report a patient who developed paralytic strabismus despite receiving antivenom injection after a snake bite on his toe and recovered following treatment with anticholinesterase.Case Summary: A 25-year-old man with no previous ophthalmological or neurological illnesses presented to our emergency room after viper bite on the left toe. Because there were no other symptoms without localized pain, he was discharged after antivenom. The next day, he returned to the emergency room with sudden onset binocular diplopia. The alternate prism cover test showed 12 prism diopters of exotropia a

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Bom, Sara, Pedro Contreiras Pinto, Helena Margarida Ribeiro, and Joana Marto. "Digital Tools in Action: 3D Printing for Personalized Skincare in the Era of Beauty Tech." Cosmetics 12, no. 4 (2025): 136. https://doi.org/10.3390/cosmetics12040136.

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3D printing (3DP) enables the development of highly customizable skincare solutions, offering precise control over formulation, structure, and aesthetic properties. Therefore, this study explores the impact of patches’ microstructure on hydration efficacy using conventional and advanced chemical/morphological confocal techniques. Moreover, it advances to the personalization of under-eye 3D-printed skincare patches and assesses consumer acceptability through emotional sensing, providing a comparative analysis against a non-3D-printed market option. The results indicate that increasing the patch

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Frutos-Rincón, Laura, José Antonio Gómez-Sánchez, Almudena Íñigo-Portugués, M. Carmen Acosta, and Juana Gallar. "An Experimental Model of Neuro–Immune Interactions in the Eye: Corneal Sensory Nerves and Resident Dendritic Cells." International Journal of Molecular Sciences 23, no. 6 (2022): 2997. http://dx.doi.org/10.3390/ijms23062997.

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The cornea is an avascular connective tissue that is crucial, not only as the primary barrier of the eye but also as a proper transparent refractive structure. Corneal transparency is necessary for vision and is the result of several factors, including its highly organized structure, the physiology of its few cellular components, the lack of myelinated nerves (although it is extremely innervated), the tightly controlled hydration state, and the absence of blood and lymphatic vessels in healthy conditions, among others. The avascular, immune-privileged tissue of the cornea is an ideal model to

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Karmase, Aniket, Ananya Agarwal, Bhagirath Patel, Parth Joshi, Simran Sethi, and Anshu Shrivastava. "An open-label, single-arm clinical study to evaluate efficacy and safety of Nyumi radiant skin gummies in healthy adult subjects with fine lines/wrinkles, hyperpigmentary spots, and under eyes dark circles." Cosmoderma 4 (January 3, 2024): 2. http://dx.doi.org/10.25259/csdm_250_2023.

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Objectives: Flawless skin is certainly the most desired feature that plays a vital cosmetic role in human being. Apart from protecting our body from environmental factors, it also protects the body from water loss and infection-causing microorganisms. However, the skin condition changes due to various ageing factors. The present study was conducted to assess the safety and efficacy of multivitamin and nutraceutical ingredients-based gummies in adult human participants. Material and Methods: An open-label, single-arm clinical study was conducted on 36 enrolled healthy males and females (in rati

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Ali, Sawan, Sergio Davinelli, Rita Mencucci, et al. "Crosslinked Hyaluronic Acid with Liposomes and Crocin Confers Cytoprotection in an Experimental Model of Dry Eye." Molecules 26, no. 4 (2021): 849. http://dx.doi.org/10.3390/molecules26040849.

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Dry eye disease (DED) is a multifactorial condition caused by tear deficiency and accompanied by ocular surface damage. Recent data support a key role of oxidative and inflammatory processes in the pathogenesis of DED. Hyaluronic acid (HA) is widely used in artificial tears to treat DED by improving ocular hydration and reducing surface friction. Crocin (Cr), the main constituent of saffron, is a renowned compound that exhibits potent antioxidant and anti-inflammatory effects. The present study was undertaken to assess the viscosity and muco-adhesiveness of a photoactivated formulation with cr

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Markosyan, A. G. "Contact Lens Care: Past, Present and Future (a Literature Review)." EYE GLAZ 23, no. 1 (2021): 29–39. http://dx.doi.org/10.33791/2222-4408-2021-1-29-39.

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Introduction. The number of contact lens users continues to increase, exceeding the total of more than 125 million people in the world. The trend of modern vision correction with contact lenses is the creation of customized contact lenses and specialty lens care products that better meet the needs of patients of all age groups.Purpose. To study the evolution of contact lens care products, their properties, composition characteristics, reliability of cleaning and disinfection, advantages and disadvantages of multifunctional solutions and peroxide systems, compatibility with contact lens materia

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Medvedev, I. B., and D. F. Pokrovsky. "Modified Immediate Sequential Bilateral Cataract Surgery (Clinical Cases)." Ophthalmology in Russia 19, no. 2 (2022): 444–47. http://dx.doi.org/10.18008/1816-5095-2022-2-444-447.

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Purpose. Analysis of two clinical cases of immediate sequential bilateral cataract surgery according to the developed modified algorithm (mаISBCS).Materials and methods. The results of two clinical cases of mаISBCS are presented. In both cases, ultrasonic cataract phacoemulsification (FEC) was performed with implantation of an intraocular lens (IOL) under local anesthesia according to the standard technique through a corneal incision of 2.2–2.4 mm. IOL calculation was performed for emmetropic refraction. The modification (compared to the traditional one) of the technology of surgical intervent

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DYBAŁA, Ewelina, Izabela DYBAŁA-PRZYGRODZKA, Artur AGHADI, Iwona CUBER, Edyta BIAŁOWĄS, and Magdalena MAZUREK. "Dry eye syndrome - vicious circle mechanism of disease." Journal of Education, Health and Sport 13, no. 3 (2023): 207–16. https://doi.org/10.12775/JEHS.2023.13.03.030.

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<strong>DYBAŁA, Ewelina, DYBAŁA-PRZYGRODZKA, Izabela, AGHADI, Artur, CUBER, Iwona, BIAŁOWĄS, Edyta & MAZUREK, Magdalena. Dry eye syndrome - vicious circle </strong><strong>mechanism</strong> <strong>of disease</strong><strong>. </strong><strong>Jo</strong><strong>urnal of Education, Health and Sport. 202</strong><strong>3</strong><strong>;1</strong><strong>3</strong><strong>(</strong><strong>3</strong><strong>):</strong><strong>207-</strong><strong>-</strong><strong>216</strong><strong>. eISSN 2391-8306. DOI </strong><strong>http://dx.doi.org/10.12775/JEHS.2023.13.03.0</strong><s

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Ostrovsky, D. S., S. A. Borzenok, B. E. Malyugin, O. P. Antonova, M. Kh Khubetsova, and T. Z. Kerimov. "Preparation and evaluation of a suspension of human corneal endothelial cells isolated from the eyes of cadaveric donors for transplantation in an <em>ex vivo</em> experiment." Russian Journal of Transplantology and Artificial Organs 26, no. 1 (2023): 103–12. http://dx.doi.org/10.15825/1995-1191-2024-1-103-112.

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Background. According to the World Health Organization, corneal diseases are one of the major causes of blindness globally. Endothelial dystrophy is one of the etiological factors leading to corneal diseases. The corneal endothelium is a monolayer of cells with virtually no mitotic activity. When the density of corneal endothelial cells falls below a critical threshold, the endothelium loses its ability to regulate corneal stromal hydration. This leads to corneal clouding and, consequently, to reduced visual acuity and quality of life of the patient. In this regard, various keratoplasty method

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Hendiger, Edyta B., Marcin Padzik, Ines Sifaoui, et al. "Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba Keratitis." Pathogens 9, no. 5 (2020): 350. http://dx.doi.org/10.3390/pathogens9050350.

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Free living, cosmopolitan amoebae from Acanthamoeba genus present a serious risk to human health. As facultative human parasites, these amoebae may cause Acanthamoeba keratitis (AK). Acanthamoeba keratitis is a severe, vision-threatening corneal infection with non-specific symptoms. The number of reported AK cases worldwide has been increasing every year. Moreover, 90% of Acanthamoeba keratitis cases are related to contact lens use. Wearing and storage contact lenses not in accordance with the physicians and manufacturers recommendations are the primary key risk factors of this disease. Amoeba

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Fierro, Adriela, Carmen Cortés, and José Eguibar. "0262 Sleep-wake cycle circadian disruption after chronic alcohol intake in a rat model of anxiety." Sleep 45, Supplement_1 (2022): A117—A118. http://dx.doi.org/10.1093/sleep/zsac079.260.

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Abstract Introduction Alcohol intake can produce disruptions in sleep-wake cycle, including circadian alterations like phase shifts. Alcohol intake is increased in subjects with anxiety to diminish its symptoms. We have selectively bred two sublines from Sprague-Dawley rats that differs on its yawning frequency. The high-yawning (HY) rats have a mean of 20 yawns/h, whereas the low-yawning (LY) rats have only 2 yawns/hour. LY male rats had high anxiety-like behavior in standardized tests and high preference for alcohol intake. The aim of this study was to assess circadian disruption of sleep-wa

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Fernandez, J. R., K. Rouzard, C. N. Webb, et al. "553 SIG-1191: A novel hydrating Cosmetic Functional Ingredient (CFI) for suborbital hyperpigmentation (under eye dark circles)." Journal of Investigative Dermatology 136, no. 5 (2016): S97. http://dx.doi.org/10.1016/j.jid.2016.02.591.

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Ng, *Gee Jin. "CARBAMAZEPINE TOXICITY WITH COMPLETE OPHTHALMOPLEGIA." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i154—i155. https://doi.org/10.1093/ijnp/pyae059.267.

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Abstract Background Carbamazepine (CMZ) is an anti-epileptic with a wide spectrum of clinical use (management of: bipolar disorder1, impulse control disorder2, trigeminal neuralgia3), however it has low margin of therapeutic range and toxicity is common if overdosed. Aim Describe a rare case of complete ophthalmoplegia (CO) from CMZ toxicity together with literature review. Method Literature search on PubMed, Google Scholar with keywords of 'carbamazepine toxicity', 'ophthalmoplegia', 'gaze paralysis' from inception to September 2023. Cases with inadequate data, and non-English reports were ex

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Zonari, Alessandra, Lear E. Brace, Fanghua Li, et al. "Clinical efficacy of OS‐01 peptide formulation in reducing the signs of periorbital skin aging." International Journal of Cosmetic Science, January 9, 2025. https://doi.org/10.1111/ics.13042.

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AbstractBackgroundThe aging of the skin, particularly around the periorbital region, is a complex process characterized by the accumulation of senescent cells, decreased collagen production, and reduced skin elasticity, leading to visible signs such as fine lines, wrinkles, and sagging.ObjectiveThis study investigates the efficacy of a novel topical formulation, OS‐01 EYE, containing the senomorphic peptide, OS‐01, along with other active ingredients, in improving the skin around the eyes.MethodsA 12‐week clinical study was conducted with 22 participants who applied OS‐01 EYE twice daily. Asse

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Gholap, Anjali, and Rachna Rastogi. "A Multicomponent Eye Cream Helps Alleviate Signs of Aging in Indian Women: A Single Center, Non-Randomized Clinical Study." Applied Drug Research, Clinical Trials and Regulatory Affairs 11 (December 2, 2024). https://doi.org/10.2174/0126673371326658241021054644.

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Introduction: The area around the eye shows the first signs of fatigue and aging. The use of suitable topical treatments can help manage the periorbital area. In this study, the efficacy of a multicomponent cream in improving the aesthetics around the eye area was ex-amined in 8 weeks. Methods: The study was a non-comparative, single-blind trial conducted on 50 Indian volun-teers with skin types III and IV for 56 days. The safety and cosmetic acceptability of the eye cream were determined by self-evaluation. The ability of the product to improve skin hydra-tion and elasticity was determined by

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Liu, Ya-Tung, Chen-Wei Lin, Chi-Chin Sun, Shih-Chieh Shao, and Nan-Ni Chen. "Bilateral keratitis associated with afatinib therapy." Taiwan Journal of Ophthalmology, February 23, 2024. http://dx.doi.org/10.4103/tjo.tjo-d-24-00003.

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Abstract: This case discussed a significant ocular side effect, bilateral keratitis, which could be induced by afatinib, an irreversible epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI). We explored the disease progression of a 52-year-old, stage IV nasopharyngeal carcinoma male patient, who was under afatinib treatment and had experienced progressive bilateral eye dryness and tenderness on increasing afatinib from 40 mg every other day to 40 mg daily. Clinical examination noted bilateral visual acuity reduction, diffuse superficial punctate keratopathy in the right eye, a

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Robic, Julie, Warren Lata, Alex Nkengne, Armelle Bigouret, and Katell Vie. "The impact of air pollution on the facial skin of Caucasian women using real‐life pollutant exposure measurements." Skin Research and Technology 30, no. 7 (2024). http://dx.doi.org/10.1111/srt.13669.

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AbstractBackgroundTo date, studies examining the effect of air pollution on skin characteristics have relied on regional pollution estimates obtained from fixed monitoring sites. Hence, there remains a need to characterize the impact of air pollution in vivo in real‐time conditions. We conducted an initial investigation under real‐life conditions, with the purpose of characterizing the in vivo impact of various pollutants on the facial skin condition of women living in Paris over a 6‐month period.Materials and methodsA smartphone application linked to the Breezometer platform was used to colle

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Choudhary, Sanjay. "Efficacy and Tolerability of an Advance Face Night Cream in Reducing Facial Pigmentation and Wrinkles in Women." Journal of Dermatology Research, August 5, 2024, 1–9. http://dx.doi.org/10.46889/jdr.2024.5209.

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Background: The efficacy and tolerance of Advance Face Night Cream in reducing facial pigmentation and wrinkles in women was evaluated. Methods: This was a monocentric, single-group, comparative, open-label study involving healthy adult women with mild to-moderate wrinkles and at least one pigmented spot on the face. The Advance Face Night Cream was to be applied every night before bedtime along with sunscreen lotion (with sun protection factor [SPF] 50) during the day. Evaluations included clinical examination and grading of wrinkles in the crow’s feet area, nasolabial region, forehead and un

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Poomanee, Worrapan, Nara Yaowiwat, Tunpidcha Pattarachaidaecharuch, and Pimporn Leelapornpisid. "Optimized multiherbal combination and in vivo anti-skin aging potential: a randomized double blind placebo controlled study." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-32738-7.

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AbstractThe present study aimed to optimize a multi-herbal combination exerting the greatest antioxidant property using statistical method for anti-skin aging application as well as to elucidate its in vivo safety and anti-skin aging potential. The multi-herbal combination was optimized using a two-level, full factorial approach by exploring the correlation between the concentrations (0–3%w/v) of three extracts from Centella asiatica (CA), Momordica cochinchinensis (MA), Phyllanthus emblica (EM). An anti-skin aging emulsion containing the optimized combination was then developed and evaluated

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Shawki, Nahed Ahmed, Abdelraheim H. Attaai, Amany Mohamed Abdel‐Mageed, and Fatma Abdel‐Regal Mahmoud. "The Role of the Eyelids of the Black‐Winged Kite, Elanus caeruleus in the Immune Protection of the Eye." Microscopy Research and Technique, December 29, 2024. https://doi.org/10.1002/jemt.24754.

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ABSTRACTThis study aimed to describe the morphological features and microstructure of the upper, lower, and third eyelids of the black‐winged kite, Elanus caeruleus, and to characterize the organized lymphoid follicles and lymphocytes in the eyelid mucosa. Additionally, it aimed to illustrate the importance of the eye adnexa in the eye's immune protection. The upper, lower, and third eyelids display varying morphological differences that seem to be closely linked to the birds' way of life, indicating adjustments to their environment and eating behaviors. The black‐winged kite has large, forwar

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Hao, Yining, Zhan Wang, and Liping Qu. "Investigating the Skin Health Benefits of Rosa roxburghii, Punica granatum and Rose: A Randomized Single‐Blind Controlled Clinical Trial." Food Science & Nutrition, October 26, 2024. http://dx.doi.org/10.1002/fsn3.4579.

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ABSTRACTRecent studies underscore the beneficial impacts of oral natural plant extracts on human skin health, though clinical evidence of their efficacy and safety is limited. This study evaluates the skin health effects of a novel oral supplement containing Rosa roxburghii, Punica granatum, and rose extracts (RPR) 0.70 healthy female participants were randomly assigned to either a control group or an RPR group, with the latter ingesting 20 mL of the RPR supplement daily on an empty stomach over 8 weeks. After 8 weeks, the RPR group exhibited significant enhancements (p < 0.001) in skin hyd

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Villapol, Maria Alexandra Carranceja, and Maria Princess L. Kanapi. "SAT-380 A Case of Primary Hyperparathyroidism on the Third Trimester of Pregnancy." Journal of the Endocrine Society 4, Supplement_1 (2020). http://dx.doi.org/10.1210/jendso/bvaa046.1884.

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Abstract Introduction: This is the case of a pregnant woman on her 3rd trimester who was diagnosed with primary hyperparathyroidism. Since there are two patients involved, the potential complications that can be brought about by the diagnostic tests and the treatment had to be weighed against the benefits. Case: The patient is SA, a 34-year old female on her 29th week of pregnancy, admitted due to a month history of abdominal pain described as intermittent, crampy, generalized, non-radiating, and mild-to-moderately severe in intensity. She was advised to do tests but did not comply. In the int

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Gendy, J. E. F., N. M. Elmowafy, M. M. Elfiky, and Y. M. Shaaban. "Assessment of Corneal Endothelial changes in type II Diabetes Mellitus by Non-Contact Specular Microscope." QJM: An International Journal of Medicine 113, Supplement_1 (2020). http://dx.doi.org/10.1093/qjmed/hcaa058.014.

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Abstract Introduction Numerous studies were dedicated to explaining the effect of type II diabetes on corneal endothelium. There seemed to be a conflict in the results of the studies, some highlighted that diabetes did not affect the corneal endothelium but rather the corneal thickness. While others disagreed stating that there was damage to the endothelium. The rest cited low endothelial cell density only in poor glycaemic control. This prospective analytical study will extensively investigate the effect of diabetes on the corneal endothelium using non-contact specular microscopy. Aim Prospec

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Badyin, I. "Rehabilitation in patients with involutional-dystrophic skin changes." April 30, 2021. https://doi.org/10.12775/JEHS.2021.11.04.019.

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Badyin I. Rehabilitation in patients with involutional-dystrophic skin changes. Journal of Education, Health and Sport. 2021;11(04): 185-193. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.04.019   https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2021.11.04.019   https://zenodo.org/record/5107021   The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of

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