Relevant bibliographies by topics / Undesired amplification

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Academic literature on the topic 'Undesired amplification'

Author: Grafiati
Published: 5 June 2025
Last updated: 15 July 2025

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Journal articles on the topic "Undesired amplification"

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Elter, Adrian, Jan P. Bogen, Jan Habermann, and Harald Kolmar. "Vom Huhn abgeleitete Antikörper für Diagnostik und Immuntherapie." BIOspektrum 27, no. 5 (2021): 500–504. http://dx.doi.org/10.1007/s12268-021-1623-3.

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AbstractDue to the large evolutionary distance between birds (Aves) und humans, immunization of chickens with human proteins results in a strong response of the bird’s adaptive immune system to proteins of mammalian origin. Additionally, chicken-derived antibodies display less undesired cross-reactivity in analytical setups than conventional rodent-derived antibodies. Due to these features as well as the facile amplification of antibody-coding genes, chicken-derived antibodies emerged as promising molecules for the immunotherapy and various biotechnological applications.
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BARIK, PRABHAT KUMAR, and Kanhu Charan Bhuyan. "Switched-Capacitor Based Preamplifier Circuit for Hearing Aid Devices." ECTI Transactions on Electrical Engineering, Electronics, and Communications 19, no. 2 (2021): 115. http://dx.doi.org/10.37936/ecti-eec.2021192.225580.

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This paper presents the design of Preamplifier circuit for hearing aid in conventional and switched-capacitor based. The proposed circuit achieves good linearity in a wide range of frequency for amplification as compared with conventional type. The total power consumption of proposed preamplifier is 5.23fW. Undesired out-band high frequency noise can be removed by the proposed preamplifier circuit before connecting to ADC of front-end hearing aid. The front-end hearing aid device occupies less area and energy efficient. The simulation of design is done by LT SPICE-IV software.
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Morán, Félix, Silvia Barbé, Saskia Bastin, et al. "The Challenge of Environmental Samples for PCR Detection of Phytopathogenic Bacteria: A Case Study of Citrus Huanglongbing Disease." Agronomy 11, no. 1 (2020): 10. http://dx.doi.org/10.3390/agronomy11010010.

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Huanglongbing (HLB) is the most devastating citrus disease and is associated with three bacterial species of the genus ‘Candidatus Liberibacter’ transmitted by insect vectors. The early detection of HLB is based on PCR methods, and it is one of the cornerstones for preventing incursion into disease-free countries. However, the detection of phytopathogenic bacteria with PCR-based methods is problematic in surveys that include a variety of samples of different origins. Here, we first report the proportion of amplifications obtained by two standardized real-time PCR methods for the diagnosis of H
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Tombácz, Dóra, Balázs Kakuk, Gábor Torma, et al. "In-Depth Temporal Transcriptome Profiling of an Alphaherpesvirus Using Nanopore Sequencing." Viruses 14, no. 6 (2022): 1289. http://dx.doi.org/10.3390/v14061289.

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In this work, a long-read sequencing (LRS) technique based on the Oxford Nanopore Technology MinION platform was used for quantifying and kinetic characterization of the poly(A) fraction of bovine alphaherpesvirus type 1 (BoHV-1) lytic transcriptome across a 12-h infection period. Amplification-based LRS techniques frequently generate artefactual transcription reads and are biased towards the production of shorter amplicons. To avoid these undesired effects, we applied direct cDNA sequencing, an amplification-free technique. Here, we show that a single promoter can produce multiple transcripti
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Carder, Hayden M., Gino Occhialini, Giovanni Bistoni, Christoph Riplinger, Eugene E. Kwan, and Alison E. Wendlandt. "The sugar cube: Network control and emergence in stereoediting reactions." Science 385, no. 6707 (2024): 456–63. http://dx.doi.org/10.1126/science.adp2447.

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Stereochemical editing strategies have recently enabled the transformation of readily accessible substrates into rare and valuable products. Typically, site selectivity is achieved by minimizing kinetic complexity by using protecting groups to suppress reactivity at undesired sites (substrate control) or by using catalysts with tailored shapes to drive reactivity at the desired site (catalyst control). We propose “network control,” a contrasting paradigm that exploits hidden interactions between rate constants to greatly amplify modest intrinsic biases and enable precise multisite editing. Whe
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Zhang, Tao, Liuguang Xiong, Zequan Pan, et al. "Design and Analysis of XY Large Travel Micro Stage Based on Secondary Symmetric Lever Amplification." Micromachines 14, no. 9 (2023): 1805. http://dx.doi.org/10.3390/mi14091805.

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This study presents a newly developed piezoelectric drive mechanism for the purpose of designing, analyzing, and testing a micro-positioning platform driven by piezoelectric actuators. The platform incorporates a piezoelectric ceramic actuator and a flexible hinge drive and features a symmetrical two-stage lever (STSL) amplification mechanism and a parallelogram output structure. The implementation of this design has led to notable enhancements in the dynamic properties of the platform, thereby eliminating the undesired parasitic displacement of the mechanism. An analytical model describing th
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Kuiava, Roman, Rodrigo A. Ramos, and Newton G. Bretas. "Robust control methodology for the design of supplementary damping controllers for FACTS devices." Sba: Controle & Automação Sociedade Brasileira de Automatica 20, no. 2 (2009): 192–205. http://dx.doi.org/10.1590/s0103-17592009000200007.

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In this paper, a new procedure to design Supplementary Damping Controllers (SDCs) for Flexible Alternating Current Transmission System (FACTS) devices is proposed. The control design problem is formulated as a search for a feasible controller subject to restrictions in the form of Linear Matrix Inequalities (LMIs). The main objective, from the application viewpoint, is the improvement of the damping ratios associated to inter-area oscillation modes. Unlike other types of formulations existing in the literature, this new formulation is capable of explicitly modeling the constraints on the contr
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Boujo, E., M. Bauerheim, and N. Noiray. "Saturation of a turbulent mixing layer over a cavity: response to harmonic forcing around mean flows." Journal of Fluid Mechanics 853 (August 23, 2018): 386–418. http://dx.doi.org/10.1017/jfm.2018.568.

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Turbulent mixing layers over cavities can couple with acoustic waves and lead to undesired oscillations. To understand the nonlinear aspects of this phenomenon, a turbulent mixing layer over a deep cavity is considered and its response to harmonic forcing is analysed with large-eddy simulations (LES) and linearised Navier–Stokes equations (LNSE). The Reynolds number is $Re=150\,000$. As a model of incoming acoustic perturbations, spatially uniform time-harmonic velocity forcing is applied at the cavity end, with amplitudes spanning the wide range 0.045–8.9 % of the main channel bulk velocity.
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Mohd Ali, Mohammad Ridhuan, Lee Lih Huey, Phiaw Chong Foo, et al. "Duplex TaqMan Hydrolysis Probe-Based Molecular Assay for Simultaneous Detection and Differentiation of Burkholderia pseudomallei and Leptospira spp. DNA." BioMed Research International 2019 (July 2, 2019): 1–6. http://dx.doi.org/10.1155/2019/9451791.

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Melioidosis and leptospirosis, caused by two different bacteria, Burkholderia pseudomallei and Leptospira spp., are potentially fatal infections that share a very similar spectrum of clinical features and cause significant mortality and morbidity in humans and livestock. Early detection is important for better clinical consequences. To our knowledge, there is no diagnostic tool available to simultaneously detect and differentiate melioidosis and leptospirosis in humans and animals. In this study, we described a duplex TaqMan probe-based qPCR for the detection of B. pseudomallei and Leptospira
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Uhlmann, Eckart, Tobias Holznagel, and Robin Clemens. "Practical Approaches for Acoustic Emission Attenuation Modelling to Enable the Process Monitoring of CFRP Machining." Journal of Manufacturing and Materials Processing 6, no. 5 (2022): 118. http://dx.doi.org/10.3390/jmmp6050118.

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Acoustic emission-based monitoring of the milling process holds the potential to detect undesired damages of fibre-reinforced plastic workpieces, such as delamination or matrix cracking. In addition, abrasive tool wear, tool breakage, or coating failures can be detected. As measurements of the acoustic emission are impacted by attenuation, dispersion, and reflection as it propagates from source to sensor, the waveforms, amplitudes, and frequency content of a wave packet differ depending on the propagation length in the workpiece. Since the distance between acoustic emission sources and a stati
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Books on the topic "Undesired amplification"

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Taberlet, Pierre, Aurélie Bonin, Lucie Zinger, and Eric Coissac. DNA amplification and multiplexing. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198767220.003.0006.

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After a brief reminder of the principles underlying the polymerase chain reaction (PCR), Chapter 6 “DNA amplification and multiplexing” discusses the choice of a DNA polymerase for the PCR. In particular, it warns against the use of proofreading polymerases, that can lead to a substantial loss of PCR specificity. Chapter 6 insists on the benefits of including different types of controls in the PCR (e.g., PCR negatives and positives, tagging system controls, etc.). The most common causes of PCR failures and their solutions are addressed, as well as the precautions to take to avoid and monitor c
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Book chapters on the topic "Undesired amplification"

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Murray, Richard M. "Design Tradeoffs." In Biomolecular Feedback Systems. Princeton University Press, 2014. http://dx.doi.org/10.23943/princeton/9780691161532.003.0007.

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This chapter describes some of the design tradeoffs arising from the interaction between synthetic circuits and the host organism. It first considers the effects of competition for shared cellular resources on circuits' behavior. In particular, circuits (endogenous and exogenous) share a number of cellular resources. The insertion or induction of synthetic circuits in the cellular environment changes for these resources, with possibly undesired repercussions on the functioning of the circuits. Independent circuits may become coupled when they share common resources that are not in overabundance. This fact leads to constraints among the concentrations of proteins in synthetic circuits, which should be accounted for in the design phase. Next, the chapter looks at the effect of biological noise on the design of devices requiring high gains. Specifically, the chapter illustrates possible design tradeoffs between retroactivity attenuation and noise amplification that emerge due to the intrinsic noise of biomolecular reactions.
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Conference papers on the topic "Undesired amplification"

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Stöhr, Michael, Kilian Oberleithner, Moritz Sieber, Zhiyao Yin, and Wolfgang Meier. "Experimental Study of Transient Mechanisms of Bi-Stable Flame Shape Transitions in a Swirl Combustor." In ASME Turbo Expo 2017: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/gt2017-65003.

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Sudden changes of flame shape are an undesired, yet poorly understood feature of swirl combustors used in gas turbines. The present work studies flame shape transition mechanisms of a bistable turbulent swirl flame in a gas turbine model combustor, which alternates intermittently between an attached V-form and a lifted M-form. Time-resolved velocity fields and 2D flame structures were measured simultaneously using high-speed stereo-PIV and OH-PLIF at 10 kHz. The data analysis is performed using two novel methods that are well adapted to the study of transient flame shape transitions: Firstly,
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Grenier, Martin, and Cle´ment Gosselin. "Kinematic Optimization of a Robotic Joint With Continuously Variable Transmission Ratio." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48443.

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The range of possible tasks achievable by robots highly depends on the selection of motors and transmissions. For example, variable ratio transmissions surpass single ratio transmissions because they can modify the torque-speed parameters of the actuator and, therefore, maintain the optimal power output state from the motor. Consequently, the use of variable ratio transmissions may expand a robot’s achievable tasks. A robotic joint with continuously variable transmission ratio is presented in this paper. This new type of transmission joint may be used in serial or parallel robots. The transmis
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Borboni, Alberto, Matteo Lancini, and Rodolfo Faglia. "Residual Vibration Reduction With Commanded Motion Optimization." In ASME 2014 12th Biennial Conference on Engineering Systems Design and Analysis. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/esda2014-20071.

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Residual vibrations affect machines at the end of commanded motion and represent an amplification factor for the work cycle. Furthermore, in repetitive cyclic movements, residual vibrations can lead to an important degeneration of the executed motion, due to a summation effect of undesired dynamic phenomena. For these reasons, the problem of residual vibrations is widely studied in literature and it is faced with different techniques. A first type of approach consists in the production of a structural device realized with proper mechanical solutions devoted to avoid the sources of vibrations.
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