Academic literature on the topic 'United States. Navy. Medical Department'
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Journal articles on the topic "United States. Navy. Medical Department"
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Ulcickas Yood, Marianne, Susan Jick, Catherine Vasilakis-Scaramozza, Bonnie M. K. Donato, Ioannis Tomazos, Gilbert L'Italien, Nicholas Sicignano, and Brian L. Feldman. "Baseline Characteristics of Patients with Paroxysmal Nocturnal Hemoglobinuria Identified in the Department of Defense Database." Blood 132, Supplement 1 (November 29, 2018): 5830. http://dx.doi.org/10.1182/blood-2018-99-113478.
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Abstract Background: Rare diseases are often characterized by misdiagnosis resulting in delays in critical and potentially lifesaving treatment. Awareness of first signs and symptoms of rare diseases can provide clinical evidence for early and accurate diagnosis. Medical records are the primary source of clinical information from first signs and symptoms to key clinical disease related events, yet access to records can be difficult and time consuming. We conducted a study using a large electronic medical record (EMR) and claims database to identify and describe characteristics of Paroxysmal Nocturnal Hemoglobinuria (PNH) patients at the time of their PNH diagnosis. We present baseline findings of the PNH population identified in the Department of Defense (DOD) healthcare system, where all clinical details were readily available. The DOD healthcare system is a US-based, longitudinal EMR and claims database with health information on approximately 10 million active beneficiaries throughout the country. Methods: We identified all people in the DOD database from January 01, 2007 through May 31, 2017 who had an ICD-10-CM code for PNH or a NDC or HCPCS code for eculizumab, the drug used to treat PNH. There is no ICD-9-CM code for PNH. Cases had no other indication for eculizumab use and had to have appropriate symptoms, comorbidities or lab results to be considered a case. We reviewed the electronic record for each patient and classified each as definite/likely, probable/possible or unlikely PNH based on attributes of the available health data including codes for eculizumab, flow cytometry, lab results, hemoglobinuria, aplastic anemia, pancytopenia and other comorbidities. Our ruling was validated by medical record review by a clinical expert for all equivocal cases and a sample of definite/likely cases. Individuals classified as unlikely PNH were excluded. Patient characteristics at PNH diagnosis are presented using descriptive statistics. Results: We identified 73 PNH patients (55% female) after review of all available electronic data; 41 had a diagnosis of PNH and received eculizumab, 17 had a diagnosis of PNH only, and 15 received eculizumab only. From these, 61 patients were determined to have definite/likely PNH and 12 had probable/possible PNH. The use of eculizumab ranged from 0 to 378 (median=18) prescriptions, dependent in part on the amount of follow-up in the database. There were 19 patients (26%) who had prevalent PNH and 54 (74%) who were newly diagnosed with PNH during the study period. Among newly diagnosed patients, the median age at PNH diagnosis was 46 years (range 13 - 86). Most patients had codes for hemoglobinuria at or before the PNH diagnosis date (69%), and many had codes for aplastic anemia (46%), thrombocytopenia (56%), and pancytopenia (28%). At any time after the PNH diagnosis, 85% had unspecified anemia, 52% had aplastic anemia, 53% had thrombocytopenia, and 33% had pancytopenia codes in their records. See table. Conclusion: From a population of around 10 million actively enrolled patients, across a 10-year study period, we identified 73 patients with PNH. Data from these patients will be used to identify patterns of health encounters leading up to diagnosis and relevant outcomes following diagnosis. This information can be used to help diagnose other patients with this rare disease and to improve their medical outcomes. Disclaimer Statement: Research data were derived from an approved Naval Medical Center, Portsmouth, VA IRB protocol (NMCP.2017.0080). The views expressed in this abstract are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense or the United States Government. Copyright Notice: CAPT Brian Feldman is a military service member. This work was prepared as part of his official duties. Title 17 U.S.C. 105 provides that 'Copyright protection under this title is not available for any work of the United States Government.' Title 17 U.S.C. 101 defines a United States Government work as a work prepared by a military service member or employee of the United States Government as part of that person's official duties. Table. Table. Disclosures Ulcickas Yood: Alexion Pharmaceuticals, Inc.: Other: Employee of EpiSource, LLC, which was contracted by Alexion Pharmaceuticals, Inc. EpiSource had the final decision on content. . Jick:Alexion Pharmaceuticals, Inc.: Other: Employee of the Boston Collaborative Drug Surveillance Program, which was contracted and paid by Alexion Pharmaceuticals, Inc. to work on a study of PNH using DOD data. . Vasilakis-Scaramozza:Alexion Pharmaceuticals, Inc.: Other: Employee of the Boston Collaborative Drug Surveillance Program, which was contracted and paid by Alexion Pharmaceuticals, Inc. to work on a study of PNH using DOD data.. Donato:Alexion Pharmaceuticals Inc: Employment, Equity Ownership. Tomazos:Alexion Pharmaceuticals, Inc.: Employment, Equity Ownership. L'Italien:Alexion Pharmaceuticals, Inc.: Equity Ownership, Other: Former employee and current stockholder of Alexion Pharmaceuticals, Inc. . Sicignano:Alexion Pharmaceuticals, Inc.: Other: Employee of Health ResearchTx, which has a business relationship with Alexion Pharmaceuticals, Inc.. Feldman:Alexion Pharmaceuticals, Inc.: Other: Employee, Department of Navy, United States Government..
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Ulcickas Yood, Marianne, Susan Jick, Catherine Vasilakis-Scaramozza, Bonnie M. K. Donato, Ioannis Tomazos, Gilbert L'Italien, Nicholas Sicignano, and Brian L. Feldman. "The Value of Population Based Data to Study Rare Diseases: An Example Using the Department of Defense Healthcare System." Blood 132, Supplement 1 (November 29, 2018): 5829. http://dx.doi.org/10.1182/blood-2018-99-113497.
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Abstract Background: For patients suffering from rare diseases, accurate and early diagnosis is critical and often lifesaving, whereas misdiagnosis can be fatal. While patient registries are useful and necessary, they may not provide reliable patient population denominators or sufficient longitudinal clinical follow-up. Access to complete and integrated patient records necessary to capture full clinical history can be challenging. Commonly, there is a lack of centralized and continuous care in the health care systems of many countries, including the United States (US). It is also challenging to identify a sufficient number of cases to provide robust results because of the rare nature of these diseases. We describe a healthcare system that can identify patients for research purposes, who have rare diseases, by accessing de-identified electronic clinical details. We used Paroxysmal Nocturnal Hemoglobinuria (PNH) as an example of a rare disease for this abstract. Methods: The Department of Defense (DOD) healthcare system is a US-based, longitudinal electronic health record (EHR) and claims database with health information on approximately 10 million active beneficiaries across the country. We evaluated the feasibility to conduct studies of rare diseases in the DOD healthcare system by assessing the capability to identify patients with PNH and to describe their course of disease and treatment. We used ICD 9/10 diagnosis codes, NDC and HCPCS codes, laboratory data and PNH treatment codes to identify patients with a clinical course consistent with PNH. Patients were classified as definite/likely, probable/possible or unlikely PNH based on the available clinical evidence and then findings were validated against review of patient records by a clinical expert. Individuals classified as unlikely PNH were excluded from the study. The clinical information on these patients will be used to understand the course of PNH in patients with and without treatments and to describe their treatment adherence and disease activity over time. Results: We identified 244 people with a diagnosis or treatment code that was indicative of PNH during years 2007-2017; 71% of the patients had electronic records that covered 10 or more years starting as early as 2003 and extending as far as 2017. From these 244 patients, we identified 73 patients with a definite/likely or probable/ possible PNH diagnosis. An ICD-10 code for PNH or a prescription for eculizumab (PNH treatment) were required, but not sufficient to confirm the presence of PNH. There is no ICD-9 code for PNH. Cases had no other indication for eculizumab use and had to have appropriate symptoms, comorbidities or lab results to be considered a case. Patients with only 1 code for PNH and no treatment were assumed to have unconfirmed disease and were excluded. 27 cases, including those with no eculizumab and a random sample of likely cases, were reviewed to validate the PNH diagnoses in collaboration with DOD treating physicians. Conclusion: The DOD healthcare system is a valuable and cost effective resource for the study of rare diseases in a timely manner. We have demonstrated the ability to identify a validated series of PNH cases that will provide important clinical insights for identifying and treating new PNH cases. This healthcare system provides long patient follow-up, demographics similar to the US population, and access to records in an integrated inpatient, outpatient and ER system that encompasses all patient care. Disclaimer Statement: Research data were derived from an approved Naval Medical Center, Portsmouth, VA IRB protocol (NMCP.2017.0080). The views expressed in this abstract are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense or the United States Government. Copyright Notice: CAPT Brian Feldman is a military service member. This work was prepared as part of his official duties. Title 17 U.S.C. 105 provides that 'Copyright protection under this title is not available for any work of the United States Government.' Title 17 U.S.C. 101 defines a United States Government work as a work prepared by a military service member or employee of the United States Government as part of that person's official duties. Disclosures Ulcickas Yood: Alexion Pharmaceuticals, Inc.: Other: Employee of EpiSource, LLC, which was contracted by Alexion Pharmaceuticals, Inc. EpiSource had the final decision on content. . Jick:Alexion Pharmaceuticals, Inc.: Other: Employee of the Boston Collaborative Drug Surveillance Program, which was contracted and paid by Alexion Pharmaceuticals, Inc. to work on a study of PNH using DOD data. . Vasilakis-Scaramozza:Alexion Pharmaceuticals, Inc.: Other: Employee of the Boston Collaborative Drug Surveillance Program, which was contracted and paid by Alexion Pharmaceuticals, Inc. to work on a study of PNH using DOD data.. Donato:Alexion Pharmaceuticals Inc: Employment, Equity Ownership. Tomazos:Alexion Pharmaceuticals, Inc.: Employment, Equity Ownership. L'Italien:Alexion Pharmaceuticals, Inc.: Equity Ownership, Other: Former employee and current stockholder of Alexion Pharmaceuticals, Inc. . Sicignano:Alexion Pharmaceuticals, Inc.: Other: Employee of Health ResearchTx, which has a business relationship with Alexion Pharmaceuticals, Inc.. Feldman:Alexion Pharmaceuticals, Inc.: Other: Employee, Department of Navy, United States Government..
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Hickman, Jonathan, and Joseph An. "Kikuchi-Fujimoto Disease: A Case Report." Blood 138, Supplement 1 (November 5, 2021): 4189. http://dx.doi.org/10.1182/blood-2021-152440.
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Abstract Kikuchi-Fujimoto: A Case Report Hickman, JD. MD LT MC USN and An, Joseph, DO. LCDR MC USN Naval Medical Center Portsmouth 620 Johns Paul John Cir, Portsmouth VA 757-953-2223 The views expressed in this abstract are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States Government. We are military service members and employees of the U.S. Government. This work was prepared as part of my official duties. Title 17 U.S.C. 105 provides that "Copyright protection under this title is not available for any work of the United States Government." Title 17 U.S.C. 101 defines a United States Government work as a work prepared by a military service member or employee of the United States Government as part of that person's official duties. Kikuchi-Fujimoto disease is a rare benign disorder often presenting with tender cervical lymphadenopathy, fever, and malaise. While first described in Japan, its distribution is worldwide and predominantly seen in young adults. Diagnosis is based on characteristic histopathologic findings of patchy necrosis occupied by karyorrhectic debris and abundant histiocytes on node biopsy. The origin is unclear but associated with a preceding viral illness as well as cutaneous lupus erythematosus. Treatment is generally supportive and focused on managing tender lymph nodes. We present a case of a 28-year-old female presenting with a 2 month history of night sweats, fever, and weight loss in the setting of painful neck swelling. CT and PET/CT imaging demonstrated numerous hypermetabolic and enlarged nodes in the bilateral cervical and axillary regions. Lab studies were notable for leukopenia, anemia, and elevated inflammatory markers. A COVID-19 screening was negative. Excisional biopsy of a cervical node revealed extensive cortical necrosis and apoptotic debris with scattered histiocytes and plasmacytoid dendritic cells in absence of neutrophils or a monoclonal B cell or T cell population. Treatment was initiated with NSAIDs and close monitoring. The patient exhibited a complete response after two months. Our case is an important reminder that lymphadenopathy, fever, and night sweats in a young adult are not pathognomonic for lymphoma. Nonetheless, a high suspicion for lymphoma should be maintained and followed with an expedited workup. Kikuchi-Fujimoto can certainly mimic Hodgkin lymphoma or other serious conditions like lupus erythematosus and tuberculosis. The diagnosis is largely one of exclusion following a careful examination of a lymph node histopathology and must be considered in young previously healthy adults to avoid misdiagnosis and unnecessary escalation of treatment. Disclosures No relevant conflicts of interest to declare.
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Summers, Shane M., Christopher J. Nagy, Michael D. April, Brandon W. Kuiper, Rechell G. Rodriguez, and Woodson S. Jones. "The Prevalence of Faculty Physician Burnout in Military Graduate Medical Education Training Programs: A Cross-Sectional Study of Academic Physicians in the United States Department of Defense." Military Medicine 184, no. 9-10 (April 3, 2019): e522-e530. http://dx.doi.org/10.1093/milmed/usz055.
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Abstract Introduction In military populations, physician burnout has potential to adversely affect medical readiness to deploy in support of joint operations. Burnout among Graduate Medical Education (GME) faculty may further threaten the welfare of the medical force given the central role these officers have in training and developing junior physicians. The primary aim of this investigation was to estimate the prevalence of burnout among faculty physicians in United States (US) Army, Navy, and Air Force GME programs. Materials and Methods We conducted a cross-sectional study of faculty physicians at US military GME training programs between January 2018 and July 2018. Through direct coordination with Designated Institutional Officials, we administered the Maslach Burnout Inventory Health Services Survey (MBI-HSS) via online web link to faculty physicians listed in Accreditation Data System at each sponsoring institution. In addition to the MBI-HSS, we collected demographic data and queried physicians about common occupational stressors in order to assist institutional leaders with identifying at-risk physicians and developing future interventions to address burnout. Results Sixteen of 21 institutions that currently sponsor military GME programs agreed to distribute the MBI-HSS survey to core faculty. We received completed assessments from 622 of the 1,769 (35.1%) reported physician core faculty at these institutions. Of the 622 physician respondents, 162 demonstrated high levels of emotional exhaustion and depersonalization for an estimated 26% prevalence of burnout. We identified only one independent risk factor for burnout: increasing numbers of deployments (OR 1.38, 95% CI 1.07–1.77). Physicians in our cohort who reported a desire to stay beyond their initial active duty service obligation were less likely to be classified with burnout (OR 0.45, 95% CI 0.26–0.77). The most common drivers of occupational distress were cumbersome bureaucratic tasks, insufficient administrative support, and overemphasis on productivity metrics. Conclusions We estimate that 26% of physician faculty in military GME programs are experiencing burnout. No specialty, branch of service, or specific demographic was immune to burnout in our sample. Institutional leaders in the MHS should take action to address physician burnout and consider using our prevalence estimate to assess effectiveness of future interventions.
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Eggleston, Heather, Nina Shoemaker, Christina Gariepy, Julie Norton, Kelsey Beauman, Aaron Kim, Christine Fedorchuk, James Roberts, Frederic Poly, and Renee Laird. "Immunopathogenesis of Campylobacter jejuniinfection in a small animal model." Journal of Immunology 210, no. 1_Supplement (May 1, 2023): 82.17. http://dx.doi.org/10.4049/jimmunol.210.supp.82.17.
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Abstract We set out to develop and characterize a small animal model of Campylobacter jejuni(CJ) infection that recapitulates human campylobacteriosis. Adult C57BL/6J mice are rendered susceptible to colonization and disease by pre-treatment with a zinc deficient diet and a broad-spectrum antibiotic cocktail. We have established this model with four strains with diverse capsular serotypes and flagellar groups, two key virulence factors for CJ pathogenesis. We measured colonization, weight loss, diarrhea, fecal inflammatory markers, and cytokine production by mesenteric lymphocytes and splenocytes. Diarrhea containing visible mucous and/or blood and degree of weight loss vary in severity depending on the strain and dose. Interestingly, we identified an inverse relationship between inoculum dose and levels of fecal inflammatory markers, with lower inoculum doses inducing significantly higher inflammation. We also observed production of IFNγ and IL-17 at day 9 post infection and despite no decrease in CJ colonization, IFNγ and IL-17 levels decreased by day 21 with a subsequent increase in IL-10 production. We also observed higher levels of IFNγ and IL-17 in mice challenged with strain CG8486 relative to those challenged with strain 81–176 pointing to potential strain differences. These differences observed were more striking in mesenteric lymphocytes versus splenocytes, indicating that local cellular responses differed from systemic responses. We have developed a model of inflammatory diarrhea in adult mice that exhibits hallmarks of CJ infection and further identified significant shifts in cytokine expression associated with the duration of infection, bacterial strain utilized, and therapeutic treatment. Research reported in this presentation is supported by Navy work unit number: 6000.RAD1.DA3.A0308 and CARB-X. CARB-X’s funding for this project is sponsored by the Cooperative Agreement Number IDSEP160030 from ASPR/BARDA and by awards from Wellcome Trust, the UK Global Antimicrobial Resistance Innovation Fund (GAMRIF) funded by the UK Government Department of Health and Social Care (DHSC) and the Bill & Melinda Gates Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of CARB-X or any of its funders. Disclaimers: The views expressed in this work are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, nor the U.S. Government. F. Poly is an employee of the U.S. Government. This work was prepared as part of official duties. Title 17 U.S.C. §105 provides that ‘Copyright protection under this title is not available for any work of the United States Government.’ Title 17 U.S.C. §101 defines a U.S. Government work as a work prepared by a military service member or employee of the U.S. Government as part of that person’s official duties.The animal study protocol was reviewed and approved by the Naval Medical Research Center IACUC in compliance with all applicable Federal regulations governing the protection of animals in research.
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Bauer, Elizabeth M., and Thanh Duc Hoang. "Complete Androgen Insensitivity and Decreased Bone Mineral Density." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A778—A779. http://dx.doi.org/10.1210/jendso/bvab048.1584.
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Abstract Background: Complete androgen insensitivity syndrome (CAIS) is a rare disorder of sex development and primary amenorrhea results in an XY karyotype but female phenotype. Patients with this syndrome have lower bone mineral density (BMD) when compared to age matched controls. Clinical Case: A 44-year-old phenotypic woman with a history of complete androgen insensitivity syndrome presented for follow-up. She was previously on hormone replacement therapy (HRT) at various doses from the age of 12 until her early 30s when her therapy became sporadic. At age 40, she was prescribed transdermal estrogen therapy but discontinued soon after a dermatologic reaction and had not been on any form of hormone replacement since that time. Past medical history was significant for karyotype 46 XY, osteochondritis dissecans of right ankle and bilateral orchiectomy at age 4. She was single with one adopted child. Physical examination showed a height 75 inches, weight 244 lbs and a normal heart, lung, and abdominal examinations. Laboratory results showed estradiol 12.3pg/mL(7.63-42.6), total testosterone 12.0 ng/dL(7-40), FSH 109.6 mIU/mL(25.8-134.8), LH 42.49 mIU/mL(7.7-58.5), anti-mullerian hormone < 0.015 ng/mL (0.26-5.81), inhibin B <7.0 pg/mL(<17), androstenedione 48 ng/dL(41-262), dihydrotestosterone 2.7 ng/dL(4-22) and dehydroepiandrosterone sulfate 209 ng/dL(31-701). A baseline DXA showed low bone density for age with T-score (Z-score) of -2.0 (-1.6) lumbar-spine; -1.6 (-1.2) femoral neck, -1.1 (-0.8) total hip and -2.5 (-2.0) forearm. Discussion:CAIS is caused by a mutation in the androgen receptor (AR) located on the X-chromosome causing complete unresponsiveness to androgen hormone. Karyotype is XY but feminization occurs due to aromatization of androgen to estrogen. Gonadectomy for testicular malignancy prevention is controversial as testicular tumors in CAIS is generally low and gonadal resection subjects individuals to lifelong hormone replacement. These patients also have lower BMD when compared to female or male age matched controls. This is even more apparent in those with removed gonads. Low BMD is exacerbated by poor compliance, inadequate dose or inappropriate HRT. Whether or not fracture risk is higher has yet to be elucidated. Currently, there is no guideline on how to manage low BMD including osteoporosis in this patient population. It is important to counsel patients with CAIS on BMD loss and to ensure optimization of factors that affect bone health including compliance with HRT, vitamin D/calcium intake and exercise. The views expressed in this article are those of the authors and do not reflect the official policy of the Department of Army/Navy/Air Force, Department of Defense, or the United States Government.
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Selvanesan, Benson, Sheelu Varghese, Justyna Andrys, Ricardo Arriaza, Rahul Prakash, Purushottam Tiwari, Cara Olsen, et al. "Abstract P2-17-04: Pharmacological inhibition of LY6K induced cell cycle arrest and DNA damage by disrupting the LY6K-Histone-Aurora B signaling axis." Cancer Research 83, no. 5_Supplement (March 1, 2023): P2–17–04—P2–17–04. http://dx.doi.org/10.1158/1538-7445.sabcs22-p2-17-04.
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Abstract Pharmacological inhibition of LY6K induced cell cycle arrest and DNA damage by disrupting the LY6K-Histone-Aurora B signaling axis Benson C. Selvanesan1,2, Sheelu Varghese1,2, Justyna Andrys5, Ricardo H. Arriaza6, Rahul Prakash6, Purushottam B Tiwari7, Cara Olsen8, Daniel Hupalo2,4, Yuriy Gusev5, Megha N. Patel6, Sara Contente1, Miloslav Sanda9, Aykut Uren7, Matthew D. Wilkerson3,4, Clifton L. Dalgard3,4, Linda S. Shimizu6, Maksymilian Chruszcz6, Tomasz Borowski5, Geeta Upadhyay 1,3,7. Affiliations 1 Department of Pathology, 2 Henry M. Jackson Foundation, 3 Murtha Cancer Center, 4 Department of Anatomy, Physiology, and Genetics 8 Department of Preventive Medicine and Biostatistics Uniformed Services University of the Health Sciences, Bethesda, MD, USA. 5 Jerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Cracow, Poland. 6 Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA. 7 Department of Oncology, Georgetown University Medical Center, Washington, DC, USA. 9 Max Planck Institute for Heart and Lung Research, Ludwigstrasse, 43, 61231 Bad Nauheim, Germany. Correspond Disclaimer The opinions expressed herein are those of the authors and are not necessarily representative of the official policies of the Uniformed Services University of the Health Sciences (USUHS), the Department of Defense (DOD), the United States Army/Navy/Air Force, the U.S. Government, or any other funding agencies Conflict of Interest None Acknowledgments NIH, NCI, R01 CA227694. NIH, NCI, R21CA256424. DOD, USUHS, VPR-NFP-74-9824. Biomedical Instrumentation Center, USUHS. The American Genome Center, USUHS. Antibody Characterization Program, Clinical Proteomics Tumor Analysis Consortium (CPTAC), National Cancer Institute, National Institute of Health. The Polish Grid Infrastructure, Cracow, Poland. NIH P30CA51008 and 1S10OD019982-01 to Biacore Molecular Interaction Shared Resource (BMISR), Georgetown University. ABSTRACT Increased expression of LY6K is significantly associated with poor survival outcomes in many solid cancers, including triple-negative and estrogen receptor-positive breast, ovarian, gastric, head and neck, neuroblastoma, bladder, and lung cancers. Inhibition of LY6K signaling is an ideal therapeutic approach for cancer, since the LY6K protein is not involved in vital organ function. Previously, we identified the small molecule NSC243928 as a binder of LY6K using surface plasmon resonance screening and showed that its activity was dependent on LY6K expression in triple-negative breast cancer cells. Here, we demonstrate the structural basis of the molecular interaction of NSC243928 with LY6K protein and the subsequent inhibition of LY6K function in mitosis and cell division via Aurora B-histone pathway. We observed that LY6K interacts with phosphorylated histones and Aurora B kinases during mitosis and that this interaction was disrupted in the presence of NSC243928. Disruption of LY6K function in mitosis/cytokinesis leads to DNA damage, senescence, and apoptosis of cancer cells. We observed that NSC243928 led to increased binding of LY6K to phosphorylated gammaH2X at S139, which was dependent on NSC243928 interaction with LY6K on phenylalanine 79. Furthermore, we observed increased levels of phosphorylated gammaH2X at S139 and increased caspase-3 activation in the tumor isografts of 4T1 and E0771 mammary tumors treated with NSC243928. These data reveal that LY6K is a novel cell cycle target for therapeutic development in triple-negative breast cancer and other solid cancers with high expression of LY6K, such as bladder cancer, head and neck, and lung cancer. Citation Format: Benson Selvanesan, Sheelu Varghese, Justyna Andrys, Ricardo Arriaza, Rahul Prakash, Purushottam Tiwari, Cara Olsen, Daniel Huplo, yuriy Gusev, Megha Patel, Sara Contente, Miloslav Sanda, Matthew Wilkerson, Clifton Dalgard, Linda S. Shimizu, Maksymilian Chruszcz, Tomasz Borowski, Geeta Upadhyay. Pharmacological inhibition of LY6K induced cell cycle arrest and DNA damage by disrupting the LY6K-Histone-Aurora B signaling axis [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P2-17-04.
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Long, Glenn, Gareth Jones, David Roper, Yasmin Eaton, and Amy Howells. "The Royal Navy Operating Department Practitioner: Perioperative care on land and sea." Journal of Perioperative Practice 30, no. 6 (September 16, 2019): 176–82. http://dx.doi.org/10.1177/1750458919864826.
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Royal Navy Operating Department Practitioners are employed in a number of different roles, during peacetime, humanitarian aid operations and periods of war. In recent times, Royal Navy Operating Department Practitioners have deployed on active operations in addition to working in NHS hospitals at home in the United Kingdom. This article will explore the different avenues and experiences of Operating Department Practitioners who are currently serving in the Royal Navy. The reader will then also gain an insight into the different echelons of care provided by the Defence Medical Services to the United Kingdom Armed Forces and Allied Nations. The article will then consider the unique experiences available to Royal Navy Operating Department Practitioners in this multi-faceted role which offers the opportunity to explore work patterns in different environments.
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Gough, Barry M. "American sealers, the United States Navy, and the Falklands 1830–32." Polar Record 28, no. 166 (July 1992): 219–28. http://dx.doi.org/10.1017/s0032247400020684.
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ABSTRACTBy the early 1830s, American sealers expected free access to the waters and harbours of the Falkland Islands, an active rule over which had not been recognized by the United States. The US government, in the form of President Andrew Jackson and the State Department, adhered to a policy of freedom of the seas, and therefore backed the rights of American sealers to unrestricted access in the South Atlantic. After three sealing ships were impounded by the Argentinian authorities in the Falklands in 1831, the US Navy sloop Lexington, under the command of Captain Silas Duncan, destroyed the island group's capital at Puerto Soledad, and, with it, the Argentine military defences. The State Department informed the Argentine govermcnt that it had no claims, historic or actual, to the Falklands. The American policy of not recognizing the Argentine claims, which continued for half a century, did not interfere with British designs. In 1832–33 the British government issued orders for the Admiralty to send a warship to re-establish British control of the Falklands.
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Reneker, Maxine H., and Joan L. Buntzen. "Enterprise knowledge portals: two projects in the United States Department of the Navy." Electronic Library 18, no. 6 (December 2000): 392–403. http://dx.doi.org/10.1108/eum0000000005386.
Full textDissertations / Theses on the topic "United States. Navy. Medical Department"
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McGregor, James A. "Analysis of enlisted recruiting patterns within the Department of the Navy." Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1997. http://handle.dtic.mil/100.2/ADA341317.
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Cheney, Eric D. "Analysis of the Antideficiency Act in the Department of the Navy." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2002. http://library.nps.navy.mil/uhtbin/hyperion-image/02Jun%5FCheney.pdf.
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Robins, Ricky L. "Comparison of past performance practices between the Department of the Navy and commercial industry." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2002. http://library.nps.navy.mil/uhtbin/hyperion-image/02Jun%5FRobins.pdf.
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Bruggeman, John H. "A multi-year ammunition procurement model for Department of the Navy non-nuclear ordnance." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2003. http://library.nps.navy.mil/uhtbin/hyperion-image/03sep%5FBruggeman.pdf.
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Thesis (M.S. in Operations Research)--Naval Postgraduate School, September 2003.Thesis advisor(s): W. Matthew Carlyle, Gerald G. Brown. Includes bibliographical references (p. 93-94). Also available online.
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Attanasio, Henry. "Contracting for embedded computer software within the Department of the Navy." Thesis, Monterey, California : Naval Postgraduate School, 1990. http://handle.dtic.mil/100.2/ADA237192.
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Thesis (M.S. in Management)--Naval Postgraduate School, June 1990.Thesis Advisor(s): McCaffrey, Martin J. Second Reader: Abdel-Hamid, Tarek. "June 1990." Description based on title screen as viewed on October 16, 2009. DTIC Descriptor(s): Computer programs, detectors, contracts, weapon systems, navy, attitude (inclination), scheduling, procurement, delay, embedding, cost overruns, department of defense, reports DTIC Indicator(s): Naval procurement, computer programs, embedding, theses. Author(s) subject terms: Software development; software acquisition; contracting for software development; Mission Critical Computer Resources (MCCR); Embedded Computer Resources (ECR) Includes bibliographical references (p. 89-90). Also available in print.
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Cook, Glenn R. Dyer Jefferson D. "Business process reengineering using knowledge value added in support of the Department of the Navy Chief Information Officer /." Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2003. http://library.nps.navy.mil/uhtbin/hyperion-image/03sep%5FCook.pdf.
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Thesis (M.S. in Information Technology Management)--Naval Postgraduate School, September 2003.Thesis advisor(s): Thomas J. Housel, Brian Steckler. Includes bibliographical references (p. 87-88). Also available online.
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Michelsen, Christopher J. "United States Navy implementation of Department of the Defense (DoD) Public Key Infrastructure (PKI) /." Thesis, Monterey, California. Naval Postgraduate School, 1999. http://hdl.handle.net/10945/13706.
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Information assurance (IA) within DoD is becoming an increasingly difficult task as information resources are moving toward a web-based environment to counter this problem, DoD is mandating that all services implement DoD Public Key Infrastructure (PKI). DoD PKI is part of DoD's defense in depth strategy. It leverages the power of public key cryptography and digital certificates to improve IA. The thesis begins with a presentation of background information on public/private key cryptography and the elements of a PKI. The thesis then discusses those PKI management issues, i.e., CRLs and directories, that an IT manager should consider when implementing a PKI. The thesis then outlines the three areas the Navy should focus on as it implements DoD PKI; specifically PKI implementation strategies, key distribution alternatives, and how to manage change. In response to the first two areas, the author recommends regionalization, based upon the NMCI architecture, smart cards, and biometrics as answers. In response to the third area, the reader is provided with a discussion on managing change. as it relates to the implementation of DoD PKI. The thesis is concluded with a discussion of what the Navy and DoD needs to do in order to implement the ideas presented in this thesis.
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Butler, Terri L. "The impact of force reductions on promotions in the Navy Medical Service Corps." Thesis, Monterey, California : Naval Postgraduate School, 1990. http://handle.dtic.mil/100.2/ADA241816.
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Thesis (M.S. in Management)--Naval Postgraduate School, December 1990.Thesis Advisor(s): Milch, Paul R. Second Reader: Suchan, James E. "December 1990." Description based on title screen as viewed on April 01, 2010. DTIC Descriptor(s): Computer programs, decision making, impact, information systems, models, theory, rates, theses, reduction, manpower, strength(general), inventory, flow, surgery, promotion(advancement), Markov processes, policies DTIC Identifier(s): Manpower, computerized simulation, military medicine, navy, medical service corps, force model, Markov chain theory, BUMIS (burean of medicine and surgery information system), theses, forecasting. Author(s) subject terms: Includes bibliographical references (p. 123-124). Also available in print.
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Senter, Jasper W. Thornton Cayetano S. "Information technology (IT) ethics : training and awareness materials for the Department of the Navy /." Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2002. http://library.nps.navy.mil/uhtbin/hyperion-image/02Jun%5FThornton%5FSenter.pdf.
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Thesis (M.S.)--Naval Postgraduate School, 2002.Thesis advisor(s): Cynthia E. Irvine, Floyd Brock. Jasper W. Senter graduated in September, 2002; Cayetano S. Thornton graduated in June, 2002. Includes bibliographical references (p. 59-61). Also available online.
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Greenhoe, Richard J. "Comparison of retention characteristics over time : evidence from the 1992 and 1999 Department of Defense survey of active duty personnel /." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 2005. http://library.nps.navy.mil/uhtbin/hyperion/05Mar%5FGreenhoe.pdf.
Full textBooks on the topic "United States. Navy. Medical Department"
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United States. Navy Dept. Bureau of Medicine and Surgery. Professional Development Division. and United States. Navy Dept. Bureau of Medicine and Surgery., eds. U.S. Navy Medical Department officer career guide. Washington, DC: Bureau of Medicine and Surgery, 1991.
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P, Gray David. Many specialties, one corps: A pictorial history of the U.S. Navy Medical Service Corps. Virginia Beach, Va: Donning Co., 1997.
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United States. Navy Dept. Bureau of Medicine and Surgery, ed. General Medical Officer (GMO) manual. 9th ed. Washington, DC (2300 E St., NW, Washington 20372-5300): Bureau of Medicine and Surgery, 1996.
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Corps, United States Marine, ed. The History of the Medical Department of the United States Navy in World War II. [Washington, D.C.]: U.S. Marine Corps, 1989.
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United States. Navy Dept., ed. Financial management: Navy records contain billions of dollars in unmatched disbursements : report to the Acting Secretary of the Navy. Washington, D.C: The Office, 1993.
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Office, General Accounting. Financial management: Profile of Navy and Marine Corps financial managers : report to the Acting Assistant Secretary of the Navy (Financial Management and Comptroller). Washington, D.C. (P.O. Box 37050, Washington, D.C. 20013): The Office, 1998.
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Office, General Accounting. Military personnel: Navy enlisted personnel management : fact sheet for congressional requesters. Washington, D.C: The Office, 1990.
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Omori, Frances. Quiet heroes: Navy nurses of the Korean War 1950-1953, Far East Command. 5th ed. Saint Paul, MN: Smith House Press, 2000.
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United States. General Accounting Office. Office of the General Counsel., ed. [Protest of Navy rejection of bid for asbestos removal]. Washington, D.C: The Office, 1993.
Find full textBook chapters on the topic "United States. Navy. Medical Department"
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McGuire, Frederick L. "Enter the Medical Service Corps." In Psychology aweigh! A history of clinical psychology in the United States Navy, 1900-1988., 49–53. Washington: American Psychological Association, 1990. http://dx.doi.org/10.1037/10069-006.
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"Growing Up in New York City, Medical School and the United States Navy." In Emperor of Enzymes, 1–16. WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789814699822_0001.
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Beisner, Robert L. "Acheson, the presiden , and the state department." In Dean Acheson, 103–26. Oxford University PressNew York, NY, 2006. http://dx.doi.org/10.1093/oso/9780195045789.003.0007.
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Abstract Introduction It had not been so long since all the employees of the state department could pose together on the front steps in annual pictures. By January 1949, however, five times as many people worked in its new building at Foggy Bottom as in the old State-War-Navy headquarters on Pennsylvania Avenue. The department employed a little over 600 people in the early 1920s, nearly 1,000 by the eve of World War II, and almost 6,000 by 1948. In 1947, it had approximately 12,000 Americans working abroad; in 1950, the figure was nearly 16,000. From 1938 to 1948, the staff of the office of the secretary of state rose from 21 to 186 and workers in the geographic and political offices from 112 to 318. The United States was served by 737 career diplomats in 1936, 1,217 in 1950. Around the world in 1951, the department ran 59 embassies, 14 legations, and 196 consular offices, and people on the State payroll helped run the occupation regimes in Germany and Japan. Department appropriations rose from $2.6 to $33.7 million from 1938 to 1948, money that paid for a rising tide of communications —by 1950, 25,000 incoming and outgoing telegrams and 250,000 memos and other official messages.
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Moore, John Norton. "The UNCLOS Treaty and Its Negotiation." In The Struggle for Law in the Oceans, 3—C1N21. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/oso/9780197626962.003.0001.
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Abstract This chapter discusses the problem of “creeping jurisdiction” as it threatened navigational freedom, and overall American concerns about the regime for the oceans under the 1958 Geneva Conventions which led the United States to open negotiations leading to UNCLOS. It discusses the multi-decade history of the negotiations. It describes the unique double hatted office, D/LOS, which enabled the United States to develop negotiating instructions with the participation of some eighteen departments and agencies and to provide effective leadership in the negotiations. Of particular note, the Department of Defense, the Joint Chiefs of Staff, the Navy, the Coast Guard, and the Environmental Protection Agency were involved, as well as the State Department and an extensive private sector advisory group, throughout the process. Both navigational freedom and United States access to the mineral resources of the deep seabed were set as “no-sign” issues for the United States. The Chapter then describes the initial failure of the negotiations with respect to deep seabed mining and how President Ronald Reagan set forth six conditions which led some years later to a renegotiation of that part of the Convention meeting all of Reagan’s conditions. UNCLOS is now in force for 168 countries and the European Union and was a stunning success for the United States. The Chapter ends with an overview discussion of the principal provisions of the Convention in its 320 articles and 9 annexes, and the subsequent Senate Foreign Relations Committee favorable report of the Convention to the full United States Senate in both 2004 and 2007.
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Ramgopal, Sriram. "Sepsis Alert." In Pediatric Medical Emergencies, 73–82. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190946678.003.0008.
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Sepsis is defined as the presence of systemic inflammatory response syndrome from a presumed infectious etiology. Septic shock is defined as the presence of sepsis with cardiovascular organ dysfunction. Approximately 20,000 to 40,000 cases of pediatric sepsis occur in the United States annually, and sepsis carries a mortality rate of 5% to 10%. Because the diagnostic criteria lack specificity and because hypotension is a late finding, sepsis can be difficult to diagnose in children. A delay in treatment is associated with an increased mortality rate. The use of electronic screening tools, history and physical exam, and prudent use of laboratory testing can facilitate detection of sepsis, though no single method is reliable. Resuscitation with antibiotics and rapid administration of fluid boluses, combined with the use of pressors in fluid refractory cases, are the mainstays of therapy, with a goal to deliver critical therapies within 1 hour of emergency department presentation.
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Horton, Destiny, and Mohan Punja. "The Rummy Rum Rums: Alcohol Intoxication." In Medical Toxicology, 259–68. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197635513.003.0023.
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Abstract A primary alcohol, an alkyl alcohol, and a volatile organic compound; when put into such terms, it would seem that ethanol, more commonly known as alcohol, would not be particularly appealing to society. However, it is one of the most abused substances in the world, with an estimated 3 million deaths globally ascribed to its consumption. In the United States, close to 100,000 people per year die from alcohol-related causes. As a drug, ethanol is unique in that healthcare providers will care for many patients suffering from acute and chronic complications, yet this drug is legal in most countries and is also used by millions of people across the world as part of a culture of entertainment, cuisine, or personal use in the home. With a drug used so frequently with such a high prevalence of complications, what should the clinician expect when a patient who has consumed alcohol is brought into the emergency department and how will their care be managed? This chapter discusses pathophysiology, toxicology, and general management of the inebriated patient and some of the complications of frequent alcohol use.
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Sabet, Kevin A., and Ken C. Winters. "Policy Implications." In Contemporary Health Issues on Marijuana, 295–306. Oxford University Press, 2018. http://dx.doi.org/10.1093/med-psych/9780190263072.003.0012.
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This chapter reviews policy implications associated with legalizing marijuana for medical and recreational purposes. The authors discuss the current landscape and attitudes toward marijuana use and review the enforcement polices of the federal government, including the impact of policies within the United States Department of Justice and the United States Government Accountability Office. The chapter also examines the expanding marijuana industry and warns against the growth of ‘Big Marijuana’ and the industry’s ability to influence policy. Finally, after reviewing the important pros and cons of legalizing this drug, the authors offer several guidelines for states to optimize care when legalization is implemented.
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Balfour, Margaret E., and Matthew L. Goldman. "Collaborations Beyond the Emergency Department." In Emergency Psychiatry, edited by Tony Thrasher, 463—C24P110. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197624005.003.0024.
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Abstract A lot happens outside of the emergency department (ED) that affects the outcome of a behavioral health emergency. Many ED visits originate with a call for help from someone in the community, and there is wide variability throughout the United States in how that call for help is handled. Some people experiencing mental health or substance use related emergencies never make it to the ED, instead dying in police shootings or taken to jail instead of receiving the care they need. Fortunately, the new 988 mental health emergency number and police reform movements have created momentum for building behavioral health crisis response systems that deliver the same quality and consistency of care as expected for medical emergencies. As crisis systems grow and evolve, collaborative partnerships will be critical for solving problems that have long burdened the ED, such as psychiatric boarding and the “revolving door” of repeat ED utilization. This chapter discussed the growing number of options for crisis care outside the ED and provides practical suggestions for successful collaboration. The role of law enforcement and the various approaches to lessening the impact on individuals experiencing behavioral health emergencies are also discussed. In addition, the chapter provides an overview of the crisis continuum, including crisis hotlines, mobile teams, observation units, crisis residential programs, and peer wraparound services that can help ensure linkage to aftercare is successful. Practical suggestions for collaboration are included throughout the chapter to spark ideas for action or quality improvement projects.
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Baker, Sarah E., and Adam Brenner. "The Public Psychiatrist as Educator." In Public and Community Psychiatry, 149–68. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780190907914.003.0008.
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Among the many important educator roles of the public psychiatrist is that of teacher for the medical students, residents, and fellows who rotate through her public sector clinic or hospital. Using a case study as its basis, this chapter describes how a public psychiatrist can engage with an academic medical center’s department of psychiatry in order to offer training opportunities in the public sector. It also describes the process for developing medical student clerkships and resident rotations and includes examples from clerkships and resident rotations from throughout the United States.
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Smith, Michael. "How It Began: Bletchley Park Goes to War." In Colossus. Oxford University Press, 2006. http://dx.doi.org/10.1093/oso/9780192840554.003.0009.
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The breaking of the German teleprinter cipher that led to the construction of the Colossus computer was the culmination of a series of triumphs for British codebreakers. British interception of other countries’ radio communications had begun in earnest during the First World War. The War Office ‘censored’ diplomatic communications passing through the hands of the international telegraph companies, setting up a codebreaking operation to decipher the secret messages. The British Army intercepted German military wireless communications with a great deal of success. E. W. B. Gill, one of the army officers involved in decoding the messages, recalled that ‘the orderly Teutonic mind was especially suited for devising schemes which any child could unravel’. One of the most notable successes for the British cryptanalysts came in December 1916 when the commander of the German Middle-East signals operation sent a drunken message to all his operators wishing them a Merry Christmas. With little other activity taking place over the Christmas period, the same isolated and clearly identical message was sent out in six different codes, only one of which, until this point, the British had managed to break. The army codebreaking operation became known as MI1b and was commanded by Major Malcolm Hay, a noted historian and eminent academic. It enjoyed a somewhat fractious relationship with its junior counterpart in the Admiralty, formally the Naval Intelligence Department 25 (NID25) but much better known as Room 40, after the office in the Old Admiralty Buildings in Whitehall that it occupied. The navy codebreaking organisation had an even more successful war than MI1b, recruiting a number of the future employees of Britain’s Second World War codebreaking centre at Bletchley Park, including Dillwyn ‘Dilly’ Knox, Frank Birch, Nigel de Grey, and Alastair Denniston, who by the end of the war was head of Room 40. Among the many successes of the Royal Navy codebreakers was the breaking of the Zimmermann telegram, which showed that Germany had asked Mexico to join an alliance against the United States, offering Mexico’s ‘lost territory’ in Texas, New Mexico, and Arizona in return, and brought the United States into the war.
Conference papers on the topic "United States. Navy. Medical Department"
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Siemietkowski, John S., and Walter S. Williams. "10,000 Hours of LM2500 Gas Turbine Experience as Seen Through the Borescope." In ASME 1986 International Gas Turbine Conference and Exhibit. American Society of Mechanical Engineers, 1986. http://dx.doi.org/10.1115/86-gt-269.
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The General Electric LM2500 Marine Gas Turbine, currently used by the United States Navy as main propulsion on various classes of ships, lends itself very easily to a procedure known as photoborescopy. Photoborescopy is that process where discrete, color photographs are taken of various internal parts of the engine. Borescoping in itself is not new, but maximizing the borescopes capabilities is a program that the U.S. Navy continuously is developing at the Naval Ship Systems Engineering Station (NAVSSES) in Philadelphia, Pennsylvania. This paper will describe the photoborescopy technique used by NAVSSES and also give and show graphically the Fleet experience with two LM2500’s which had accumulated 10,000 hours of successful at-sea operation. The opinions expressed herein are those of the author and not necessarily of the Department of Defense or the Navy Department.
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Rhinehart, Matthew, Robert Brymer, and Eric O'Neill. "Design and Evaluation of Control Laws for the CH-53E Low Speed Precision Control System." In Vertical Flight Society 76th Annual Forum & Technology Display. The Vertical Flight Society, 2020. http://dx.doi.org/10.4050/f-0076-2020-16388.
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The United States Marine Corps often operate their helicopters in austere environments where degraded visual environments (DVE) such as brownout are regularly encountered. DVE significantly increase the risk to operations and have led to many mishaps across the Department of Defense. In response, engineers from the United States Navy are designing a system to augment the legacy flight control system (FCS) on the CH-53E. The system is designed to preserve the legacy FCS functionality to limit the impact on the current platform airworthiness and reduce developmental flight test. The Low Speed Precision Control (LSPC) system provides decel-to-hover with position hold functionality, allowing the pilot to modulate command references via trim beepers, cyclic fly through, and trim release. A piloted simulator test was performed with three test pilots to evaluate the handling qualities with and without LSPC engaged, in several fleet representative conditions. LSPC was found to reduce workload marginally in good visual environments and in low light conditions; however more substantial reductions were shown for approaches into brownout conditions. In addition, LSPC was shown to significantly reduce lateral drift during final approach into brownout and lateral and longitudinal drift in a hover. Inherent system bandwidth limitations were found to degrade the performance of the system for anything more than moderate control inputs. Overall, LSPC was successful in augmenting fleet representative approaches in the simulator for degraded visual environments.
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Gloria, Chrismatovanie. "Compliance with Complete Filling of Patient's Medical Record at Hospital: A Systematic Review." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.04.29.
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ABSTRACT Background: The health information system, especially medical records in hospitals must be carried out accurately and completely. Medical records are important as evidence for the courts, education, research, and policy makers. This study aimed to investigate the factors affecting the compliance with completeness of filling patient’s medical records at hospitals. Subjects and Methods: A systematic review was conducted by searching from ProQuest, Scopus, and National journals using keywords medical records, filling of medical records, and non- compliance filling medical records. The abstracts and full-text articles published between 2014 to 2019 were selected for this review. A total of 62,355 articles were conducted screening of eligibility criteria. The data were reported using PRISMA flow chart. Results: Eleven articles consisting of eight articles using observational studies and three articles using experimental studies met the eligible criteria. There were two articles analyzed systematically from the United States and India, two articles reviewed literature from the United States and England, and seven articles were analyzed statistically from Indonesia, America, Australia, and Europe. Six articles showed the significant results of the factors affecting non-compliance on the medical records filling at the Hospitals. Conclusion: Non-compliance with medical record filling was found in the hospitals under study. Health professionals are suggested to fill out the medical record completely. The hospital should enforce compliance with complete medical record filling by health professionals. Keywords: medical record, compliance, hospital Correspondence: Chrismatovanie Gloria. Hospital Administration Department, Faculty Of Public Health, Universitas Indonesia, Depok, West Java. Email: chrismatovaniegloria@gmail.com. Mobile: +6281321161896 DOI: https://doi.org/10.26911/the7thicph.04.29
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Fardink, Paul. "Operation Ivory Soap and the Largest Helicopter Rescue of WWII." In Vertical Flight Society 79th Annual Forum & Technology Display. The Vertical Flight Society, 2023. http://dx.doi.org/10.4050/f-0079-2023-18085.
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Until recently, Operation Ivory Soap, a secret World War II collaboration between the United States Army, Navy, and Merchant Marines, to reconfigure six Liberty Ships into floating maintenance shops for repairing damaged aircraft in the Pacific, remained in obscurity. Sikorsky R-4B and R-6A helicopters were based on these ships to ferry mechanics and parts wherever needed. This secret project proceeded as planned until an emergency request for medical evacuation of wounded soldiers came in June 1945. Until then, the newly-developed helicopter had rarely been used for aeromedical rescue and never in hostile action. Nonetheless, the incredibly brave and resourceful Ivory Soap pilots, flying without radios, medical training, or specialized transport equipment, saved as many as ninety-four seriously-injured troops in the Philippines - and forever revolutionized the value of the helicopter in combat. Sadly, the pilots' stories of valor lay buried in forgotten piles of once-classified documents for decades. But no longer....
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Steuart, Shelby. "Do Cannabis PDMPs Change Physician Prescribing Behavior?" In 2022 Annual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2022. http://dx.doi.org/10.26828/cannabis.2022.02.000.42.
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As legal medical cannabis has become widespread in the United States, cannabis-related emergency department visits have increased. One reason for this increase is that physicians cannot prescribe medical cannabis, leading to a situation where physicians must rely on their patients to tell them whether they use medical cannabis. Patients may withhold their use of cannabis from their physician out of fear of judgment or fear of changes to their prescriptions. At the same time, almost 400 medications have moderate or severe contraindications for use with cannabis, any of which could cause a poisoning severe enough to warrant hospitalization. To combat this problem of information asymmetry in patient cannabis use, about one-third of states with medical cannabis programs have added cannabis to their state Prescription Drug Monitoring Program (PDMP) over the past few years. This could lead to changes in the physician prescribing behavior, which may result in fewer accidental cannabis-related poisonings. I will explore this question through the application of robust difference-in-difference models to private and public insurance claims data as well as data from Electronic Medical Records.
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Hsueh, Andy, Kelly Fong, Kayla Kendrics, Nadia Saddiqi, Tammy Phan, Ellen Reibling, and Brian Wolk. "Unwitting Adult Marijuana Poisoning: A Case Series." In 2021 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2022. http://dx.doi.org/10.26828/cannabis.2022.01.000.34.
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Study purpose: With increasing state legalization, marijuana use has become commonplace throughout much of the United States. This has resulted in expected and potentially dangerous consequences. Existing literature on unintentional exposure focuses primarily on the pediatric population. Despite mounting cases of unintentional exposure to marijuana, minimal research has been published on the effects of non-consensual marijuana consumption in adults. Here, we report on a cluster of adults with unwitting marijuana exposure. Methods: A cluster of patients who presented to the Emergency Department (ED) within one hour of ingesting marijuana-contaminated food at a wedding reception event were subsequently referred to the Medical Toxicology Service. We conducted a retrospective analysis of twelve subject charts who were exposed to the marijuana-contaminated food and a qualitative analysis of six of the 12 subjects’ experiences who willingly consented to be interviewed. The interviews were then analyzed and coded to categorize common themes within the subjects’ experiences. Themes categorically selected throughout the interview analysis included “Thoughts & Feelings” and “Effect on Work.” The study was approved by the Institutional Review Board. Results: Three of the subjects (25%) required prolonged observation due to persistent symptoms of acute marijuana intoxication. Eleven (92%) were urine immunoassay positive for tetrahydrocannabinol (THC). Two subjects (17%) tested positive for ethanol in their blood. None of the subjects reported a prior history of marijuana use. Common symptoms experienced by the subjects included confusion (50%), difficulty speaking (67%), nausea (25%), tremors (17%), and feelings of unreality (33%). All interviewed subjects reported sleepiness and three (50%) reported a negative impact on work. Subjects also reported multiple emotions, including anger, confusion, disbelief, and helplessness. None of the cases resulted in admission to the intensive care unit or death. Conclusions: Our case series illuminates the effects of unwitting and/or unintentional marijuana exposure in adults, with sufficient systemic effects resulting in individuals seeking emergency care. Legal and ethical barriers have limited the study of marijuana outside of controlled conditions. While the exposure in this study did not result in admission to the ICU or death, it did result in psychological distress and reported symptoms lasting weeks after the incident. As marijuana becomes readily available, the potential as an unwitting or even malicious intoxicant may increase.
Reports on the topic "United States. Navy. Medical Department"
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Miller, John, Steve Clement, Clyde Hoskins, and Howard Schloss. United States Army Medical Department Reorganization. Volume 1 - Narrative. Fort Belvoir, VA: Defense Technical Information Center, June 1995. http://dx.doi.org/10.21236/ada296647.
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Miller, John, Steve Clement, Clyde Hoskins, and Howard Schloss. United States Army Medical Department Reorganization. Volume 2 - Enclosures 1-10. Fort Belvoir, VA: Defense Technical Information Center, June 1995. http://dx.doi.org/10.21236/ada296646.
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Garrett, H. L., Frank B. Kelso, and Carl E. Mundy. Department of the Navy 1992 Posture Statement and the Fiscal Year 1993 Budget of the United States Navy and the United States Marine Corps. Fort Belvoir, VA: Defense Technical Information Center, March 1992. http://dx.doi.org/10.21236/ada247771.
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Bates, Michael M. NEPA After Natural Resources Defense Council V. United States Department of the Navy. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada417428.
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Alexander, Strashny, Christopher Cairns Christopher, and Jill Ashman J. Emergency Department Visits With Suicidal Ideation: United States, 2016–2020. National Center for Health Statistics (U.S.), April 2023. http://dx.doi.org/10.15620/cdc:125704.
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This report uses data from the 2016–2020 National Hospital Ambulatory Medical Care Survey to present the annual average emergency department visit rate per 10,000 people for patients with suicidal ideation.
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Cairns, Christopher, Jill Ashman., and J. M. king. Emergency Department Visit Rates by Selected Characteristics: United States, 2020. National Center for Health Statistics (U.S.), November 2022. http://dx.doi.org/10.15620/cdc:121837.
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This report presents characteristics of emergency department visits, including those with mentions of COVID-19, by age group, sex, race and ethnicity, and insurance using data from the 2020 National Hospital Ambulatory Medical Care Survey.
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Gindi, Renee. Health, United States, 2019. Centers for Disease Control and Prevention (U.S.), 2021. http://dx.doi.org/10.15620/cdc:100685.
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Health, United States, 2019 is the 43rd report on the health status of the nation and is submitted by the Secretary of the Department of Health and Human Services to the President and the Congress of the United States in compliance with Section 308 of the Public Health Service Act. This report was compiled by the National Center for Health Statistics (NCHS) of the Centers for Disease Control and Prevention (CDC). The Health, United States series presents an annual overview of national trends in key health indicators. The 2019 report presents trends and current information on selected measures of morbidity, mortality, health care utilization and access, health risk factors, prevention, health insurance, and personal health care expenditures in a 20-figure chartbook. The Health, United States, 2019 Chartbook is supplemented by several other products including Trend Tables, an At-a-Glance table, and Appendixes available for download on the Health, United States website at: https://www.cdc.gov/nchs/hus/ index.htm. The Health, United States, 2019 Chartbook contains 20 figures and 20 tables on health and health care in the United States. Examining trends in health informs the development, implementation, and evaluation of health policies and programs. The first section (Figures 1–13) focuses on health status and determinants: life expectancy, infant mortality, selected causes of death, overdose deaths, suicide, maternal mortality, teen births, preterm births, use of tobacco products, asthma, hypertension, heart disease and cancer, and functional limitations. The second section (Figures 14–15) presents trends in health care utilization: use of mammography and colorectal tests and unmet medical needs. The third section (Figures 16–17) focuses on health care resources: availability of physicians and dentists. The fourth section (Figures 18–20) describes trends in personal health care expenditures, health insurance coverage, and supplemental insurance coverage among Medicare beneficiaries. The Highlights section summarizes major findings from the Chartbook. Suggested citation: National Center for Health Statistics. Health, United States, 2019. Hyattsville, MD. 2021.
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Cairns, Christopher, and Kai Kang. National Hospital Ambulatory Medical Care Survey: 2019 Emergency Department Summary Tables. National Center for Health Statistics (U.S.), April 2022. http://dx.doi.org/10.15620/cdc:115748.
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These tables show the most current nationally representative data on ambulatory care visits to hospital emergency departments in the United States. Estimates are presented on selected hospital, patient, and visit characteristics using data collected in the 2019 National Hospital Ambulatory Medical Care Survey.
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Cairns, Christopher, and Kai Kang. National Hospital Ambulatory Medical Care Survey: 2020 Emergency Department Summary Tables. National Center for Health Statistics (U.S.), December 2022. http://dx.doi.org/10.15620/cdc:121911.
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These tables provide the most current nationally representative data on ambulatory care visits to hospital emergency departments in the United States. Estimates are presented on selected hospital, patient, and visit characteristics using data collected in the 2020 National Hospital Ambulatory Medical Care Survey.