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Journal articles on the topic 'University of Manitoba. St. Boniface College'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 February 2022

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1

Brott, Shirley. "News of The Academy of Neonatal Nursing." Neonatal Network 26, no. 1 (January 2007): 41–43. http://dx.doi.org/10.1891/0730-0832.26.1.41.

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Upon of the retirement of Charles Rait, RN, MSEd, PNC, Debbie Fraser Askin, RNC, MS, has agreed to work with ANN’s Executive Committee to move the Academy forward. Ms. Askin’s connection to the journal, as well as her clinical practice position at St. Boniface Hospital, Winnipeg, and teaching position at the University of Manitoba, give her a strong background in education with application to clinical practice.

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2

Skira, Jaroslav Z., and Myroslaw Tataryn. "Sowing on Good Soil: Canadian Scholarship on the Ukrainian Church(es)." East/West: Journal of Ukrainian Studies 6, no. 1 (April 2, 2019): 51–90. http://dx.doi.org/10.21226/ewjus476.

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This essay surveys material published between 1950 and 2016 by Canadian scholars who studied Ukrainian church history and theology. Particular attention is paid to works produced by members of the Eastern-rite Redemptorist and Basilian religious orders and by scholars at St. Andrew’s College and the University of Manitoba in Winnipeg, the University of Toronto and the University of St. Michael’s College in Toronto, the Canadian Institute of Ukrainian Studies at the University of Alberta, and the Metropolitan Andrey Sheptytsky Institute of Eastern Christian Studies in Ottawa.

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3

Watt, David, Sharon Wright, and Paul Dyck. "The Study of Renaissance and Reformation Books on the Canadian Prairies." Renaissance and Reformation 37, no. 3 (March 5, 2015): 235–62. http://dx.doi.org/10.33137/rr.v37i3.22464.

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This article begins by providing a survey of collections holding Renaissance and Reformation books in Saskatchewan and Manitoba in order to draw attention to the range of resources across the prairies. The article’s second section focuses on the manuscripts and rare books at the University of Manitoba in order to highlight the research opportunities afforded by individual collections and the potential benefits of exploring them in aggregate. Taken together, the collections described here—from the bibles donated by Rev. Greatorex to St. John’s College in 1897 to the remarkable collection of early books at Notre Dame College in Wilcox, Saskatchewan—can help us to consider questions about the cultural and physical place of books in Reformation and Renaissance studies as well as questions about the significance of their place on the prairies. Cet article recense d’abord les collections incluant des livres de la Renaissance et de la Réforme en Saskatchewan et au Manitoba, afin d’attirer l’attention sur les ressources dans ce domaine présentes dans les prairies canadiennes. Dans un second temps, on s’y concentre sur les manuscrits et les livres rares conservés à l’Université du Manitoba dans le but de mettre en lumière les opportunités de recherches que représentent les collections individuelles ainsi que le potentiel de les examiner dans leur ensemble. En effet, prises dans leur ensemble, les collections décrites — des bibles données par le révérend Greatorex du collège St. John en 1897 à la remarquable collection de livres anciens et d’incunables du collège Notre-Dame de Wilcox en Saskatchewan — permettent d’approcher des questions au sujet de la culture et de la répartition géographique des livres relevant des études de la Renaissance et de la Réforme, et mieux comprendre les raisons et causes de leur répartition dans les prairies.

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Rose, Alexandra V., Kevin F. Boreskie, Jacqueline L. Hay, Liam Thompson, Rakesh C. Arora, and Todd A. Duhamel. "Protocol for the WARM Hearts study: examining cardiovascular disease risk in middle-aged and older women - a prospective, observational cohort study." BMJ Open 11, no. 5 (May 2021): e044227. http://dx.doi.org/10.1136/bmjopen-2020-044227.

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IntroductionCardiovascular disease (CVD) is a leading cause of death in women. Novel approaches to detect early signs of elevated CVD risk in women are needed. Enhancement of traditional CVD risk assessment approaches through the addition of procedures to assess physical function or frailty as well as novel biomarkers of cardiovascular, gut and muscle health could improve early identification. The Women’s Advanced Risk-assessment in Manitoba (WARM) Hearts study will examine the use of novel non-invasive assessments and biomarkers to identify women who are at elevated risk for adverse cardiovascular events.Methods and analysisOne thousand women 55 years of age or older will be recruited and screened by the WARM Hearts observational, cohort study. The two screening appointments will include assessments of medical history, gender variables, body composition, cognition, frailty status, functional fitness, physical activity levels, nutritional status, quality of life questionnaires, sleep behaviour, resting blood pressure (BP), BP response to moderate-intensity exercise, a non-invasive measure of arterial stiffness and heart rate variability. Blood sample analysis will be used to assess lipid and novel biomarker profiles and stool samples will support the characterisation of gut microbiota. The incidence of the adverse cardiovascular outcomes will be assessed 5 years after screening to compare WARM Hearts approaches to the Framingham Risk Score, the current clinical standard of assessing CVD risk in Canada.Ethics and disseminationThe University of Manitoba Health Research Ethics Board (7 October 2019) and the St Boniface Hospital Research Review Committee (7 October 2019) approved the trial (Ethics Number HS22576 (H2019:063)). Recruitment started 10 October 2020. Data gathered from the WARM Hearts study will be published in peer-reviewed journals and presented at national and international conferences. Knowledge translation strategies will be created to share our findings with stakeholders who are positioned to implement evidence-informed CVD risk assessment programming.Trial registration numberNCT03938155.

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Huang, Shiqi, Carla Taylor, and Peter Zahradka. "Novel Mechanisms Related to DHA's Atheroprotective Effects in Endothelial Cells: eNOS Activity Is Regulated by DHA via p38MAPK and MSK." Current Developments in Nutrition 5, Supplement_2 (June 2021): 22. http://dx.doi.org/10.1093/cdn/nzab033_022.

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Abstract Objectives Our laboratory previously reported that docosahexaenoic acid (DHA) activates p38 mitogen-activated protein kinase (MAPK) differently in growing and quiescent human endothelial cells, which represent the atherogenic and healthy states in vivo, respectively. Endothelial nitric oxide synthase (eNOS) activity differs between these two states. Since eNOS can be regulated by p38MAPK and mitogen-stimulated kinase (MSK) is a p38MAPK substrate involved in cell proliferation and inflammation, we hypothesized that DHA's atheroprotective actions require eNOS activation via the p38MAPK/MSK pathway. Thus, our objective was to investigate the role of p38MAPK/MSK in the eNOS response to DHA and determine whether the proposed pathway is growth state-sensitive. Methods EA.hy926 cells were cultured on Matrigel-coated plates to sub-confluent and quiescent states and treated with DHA ± SB202190 or SB747651A, inhibitors of p38MAPK and MSK, respectively. eNOS activation was quantified by Western blot detection of Ser1177 phosphorylation. Results eNOS activation by DHA in EA.hy926 cells was concentration-, time-, and growth state-dependent. p38MAPK inhibition suppressed eNOS activity in sub-confluent cells and increased eNOS activity in quiescent cells, while MSK inhibition suppressed eNOS activity in both growth states. eNOS activity remained suppressed with DHA treatment under MSK inhibition and showed no dose- or growth state-dependent effects. In contrast, when p38MAPK was inhibited, high dose DHA activated eNOS in sub-confluent cells, but dose-dependently decreased the elevated eNOS activity of quiescent cells. Conclusions eNOS activity in endothelial cells is modulated by DHA via p38MAPK and MSK. The growth state-dependent regulation of p38MAPK and eNOS by DHA provides novel insight into the molecular mechanisms of DHA's atheroprotective actions in relation to health status. Funding Sources Research Manitoba, St Boniface Hospital Foundation, University of Manitoba - GETS

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Swenson Danowitz, Erica. "The Canadian Literature Archive200050David Arnason, Dennis Cooley. The Canadian Literature Archive. Department of English, University of Manitoba, Canada; Archives, Dafoe Library, University of Manitoba, Canada: St John’s College 1994 to date. http://canlit.st‐john. umanitoba.ca/Canlitx/Canlit_homepage.html No charge." Electronic Resources Review 4, no. 6 (May 2000): 55–56. http://dx.doi.org/10.1108/err.2000.4.6.55.50.

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7

Rose, Alexandra V., Todd Duhamel, Chris Hyde, Dave E. Kent, Jonathan Afilalo, Annette S. H. Schultz, Anna Chudyk, Dustin S. Kehler, Mudra Dave, and Rakesh C. Arora. "Randomised controlled trial protocol for the PROTECT-CS Study: PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery." BMJ Open 11, no. 1 (January 2021): e037240. http://dx.doi.org/10.1136/bmjopen-2020-037240.

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IntroductionIn the past 20 years, the increasing burden of heart disease in an ageing population has resulted in cardiac surgery (CS) being offered to more frail and older patients with multiple comorbidities. Frailty and malnutrition are key geriatric syndromes that impact postoperative outcomes, including morbidity, mortality and prolonged hospital length of stay. Enhanced recovery protocols (ERPs), such as prehabilitation, have been associated with a reduction in complications after CS in vulnerable patients. The use of nutritional ERPs may enhance short-term and long-term recovery and mitigate frailty progression while improving patient-reported outcomes.Methods and analysisThis trial is a two-centre, double-blinded, placebo, randomised controlled trial with blinded endpoint assessment and intention-to-treat analysis. One-hundred and fifty CS patients will be randomised to receive either a leucine-rich protein supplement or a placebo with no supplemented protein. Patients will consume their assigned supplement two times per day for approximately 2 weeks pre-procedure, during in-hospital postoperative recovery and for 8 weeks following discharge. The primary outcome will be the Short Physical Performance Battery score. Data collection will occur at four time points including baseline, in-hospital (pre-discharge), 2-month and 6-month time points post-surgery.Ethics and disseminationThe University of Manitoba Biomedical Research Ethics Board (20 March 2018) and the St Boniface Hospital Research Review Committee (28 June 2019) approved the trial protocol for the primary site in Winnipeg, Manitoba, Canada. The second site’s (Montreal, Quebec) ethics has been submitted and pending approval from the Research Ethics and New Technology Development Committee for the Montreal Heart Institute (December 2020). Recruitment for the primary site started February 2020 and the second site will begin January 2021. Data gathered from the PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery Study will be published in peer-reviewed journals and presented at national and international conferences. Knowledge translation strategies will be created to share findings with stakeholders who are positioned to implement evidence-informed change.Potential study impactMalnutrition and frailty play a crucial role in post-CS recovery. Nutritional ERPs are increasingly being recognised as a clinically relevant aspect of perioperative care. As such, this trial is to determine if leucine-rich protein supplementation at key intervals can mitigate frailty progression and facilitate enhanced postoperative recovery.Trial registration numberClinicalTrials.gov Registry (NCT04038294).

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Huang, Shiqi, Carla Taylor, and Peter Zahradka. "The Potential of Docosahexaenoic Acid (DHA) in SARS-CoV-2 Management: DHA Reduces ACE2 Levels in Endothelial Cells." Current Developments in Nutrition 5, Supplement_2 (June 2021): 227. http://dx.doi.org/10.1093/cdn/nzab029_028.

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Abstract Objectives Angiotensin-converting enzyme 2 (ACE2) is a transmembrane protein located on the surface of endothelial cells that promotes vasodilation by promoting the hydrolysis of angiotensin II. However, ACE2 also serves as the cellular receptor for SARS-CoV-2. Infection by SARS-CoV-2 can promote endothelial dysfunction which in turn is associated with greater infection severity. Long chain omega-3 fatty acids (n3 PUFA) like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are reported to prevent endothelial dysfunction. Thus, we hypothesize that treatment with n3 PUFA may suppress the actions of SARS-CoV-2 on endothelial cells, potentially through endothelial ACE2. The objective of the study was therefore to investigate whether changes in ACE2 levels occur as part of the endothelial response to n3 PUFA treatment. Methods Male fa/fa Zucker rats were randomised into 4 PUFA-based diet groups: α-linoleic acid (ALA), EPA, DHA, and linoleic acid (LA), for 8 weeks. EA.hy926 cells were cultured to sub-confluent and quiescent states and treated with various doses of DHA, EPA, and ALA for 8 or 24 h. ACE2 levels in tissues and cells were quantified by Western blotting. Results In contrast to ALA and EPA, DHA treatment significantly reduced ACE2 levels in rat heart, aorta, and kidney but not lungs after 8 weeks of diet intervention. EPA only showed this reduction compared to ALA in kidney. Interestingly, when applied to human endothelial cells in culture, DHA decreased ACE2 levels of growing EA.hy926 cells even at relatively low doses, but no significant effect was observed in quiescent cells. EPA also had an effect, but only at an extremely high dose. Conclusions DHA reduced ACE2 levels in key organs and human endothelial cells, which should produce beneficial effects by lowering the susceptibility of cells to SARS-CoV-2. Funding Sources St Boniface Hospital Foundation - Research Without Borders and University of Manitoba - GETS

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"Sequence of membrane defects during the development of genetic cardiomyopathy in hamsters *1N.S. Dhalla. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, University of Manitoba, Winnipeg, Canada R2H 2A6." Journal of Molecular and Cellular Cardiology 24 (May 1992): S44. http://dx.doi.org/10.1016/0022-2828(92)90966-4.

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"Adriamycin-induced congestive heart failure in rats *1Pawan K. Singal and T. Thomas. Div. Cardiovascular Sc., St. Boniface Gen. Hosp. Res. Centre and Dept. of Physiology, Fac. of Medicine, University of Manitoba, Winnipeg, Canada." Journal of Molecular and Cellular Cardiology 24 (May 1992): S42. http://dx.doi.org/10.1016/0022-2828(92)90958-3.

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11

"CFDR Research Showcase, Early Bird Abstracts: June 6, 2019." Canadian Journal of Dietetic Practice and Research 80, no. 3 (September 2019): 145–60. http://dx.doi.org/10.3148/cjdpr-2019-018.

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Through the support of Dietitians of Canada (DC) and the Canadian Foundation for Dietetic Research (CFDR), the 2019 Research Showcase at the DC conference represented a wide variety of practice-based nutrition research projects in Canada. The 2019 Research Showcase consisted of several new elements this year. Early Bird abstracts were considered for either oral or oral ePoster sessions. New this year was the presentation of 11 Early Bird abstracts as oral presentations within the regular conference sessions: we called these “Lightning Rounds”. The remaining 27 Early Bird abstracts were presented as oral ePosters on June 6, 2019; authors presented their research in 2–3 minutes plus 2 minutes for questions, using their ePosters. For 2019, there were 3 concurrent oral ePoster sessions. All accepted, and presented, abstracts from the Early Bird submission are published in the Journal. This research event would not be possible without the commitment and dedication of many people. On behalf of DC and CFDR, we extend a special thank you to members of our abstract review committee: Susan Campisi (University of Toronto); Elaine Cawadias (Retired); Andrea Glenn (St. Francis Xavier University); Brenda Hartman (Brescia College, Western University) Mahsa Jessri (University of Ottawa); and Jessica Lieffers (University of Alberta). Thanks also to our moderators for the Oral ePosters: Barb Anderson (Acadian University); Jane Bellman (Dietitians of Canada); Brenda Hartman (Brescia College, Western University); Jessica Lieffers (University of Alberta); Dawna Royall (Dietitians of Canada); and Lee Rysdale (Northern Ontario School of Medicine). We enjoyed interacting with many of you at the oral research presentations as we highlighted the findings from our dietetic colleagues across our country! Finally, a special thank you to Gareth Willows Tribe and Michelle Naraine at CFDR for their assistance and support throughout the review process. Christina Lengyel, PhD, RD Chair, 2019 Early Bird Committee Associate Professor Director of the Dietetics Program Human Nutritional Sciences University of Manitoba Janis Randall Simpson, PhD, RD, FDC Chair, 2019 Late Breaking Committee Professor Emerita University of Guelph Executive Director, CFDR

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"Inhibitory effect of membrane methylation on heart sarcolemmal 5$prime;-nucleotidase activity *1G. Paolillo, S. Majumder, C. Ou, V. Panagia. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre and Department of Anatomy, University of Manitoba, Winnipeg, Canada." Journal of Molecular and Cellular Cardiology 21 (July 1989): S13. http://dx.doi.org/10.1016/0022-2828(89)91254-6.

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"Effects of short- and long-chain acylcarnitines on cardiac membrane ATPases *1F. Kolar, K.R. Shah, R. Ferrari, N.S. Dhalla. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre and Departments of Physiology and Medicine, University of Manitoba, Winnipeg, Canada; and University of Brescia, Cattedra di Cardiologia, Brescia, Italy." Journal of Molecular and Cellular Cardiology 21 (April 1989): S29. http://dx.doi.org/10.1016/0022-2828(89)91589-7.

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"Dietetic Research Event: June 7 and 8, 2018." Canadian Journal of Dietetic Practice and Research 79, no. 3 (September 2018): 139–54. http://dx.doi.org/10.3148/cjdpr-2018-022.

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Vancouver, British Columbia was the host city of the 2018 Dietitians of Canada Annual Conference. Through the support of Dietitians of Canada (DC) and Canadian Foundation for Dietetic Research (CFDR), the 2018 Research Showcase was an informative exchange of research and experience-sharing efforts. The submissions for this year’s CFDR event represented the diversity of dietetic research conducted within Canada. The 2018 Research Showcase highlighted the Early Bird abstracts in 2 formats; some as 10 minutes oral sessions and others as ePosters with a short oral component. The Late Breaking abstracts were displayed as ePosters. This research event would not be possible without the commitment and dedication of many people. On behalf of DC and CFDR, we would like to extend a special thank you to members of our Early Bird abstract review committee: Susan Campisi (University of Toronto); Elaine Cawadias (Retired); Andrea Glenn (St. Francis Xavier University); Mahsa Jessri (University of Ottawa); Jessica Lieffers (University of Saskatchewan). Members of the Late Breaking abstract review committee included: Laurie Drozdowski (University of Alberta); Laura Forbes (Co-chair)(University of Guelph); Joann Herridge (Hospital for Sick Children); Grace Lee (Toronto General Hospital); Lee Rysdale (Northern Ontario School of Medicine); Jessica Wegener (Ryerson University); Sarah Woodruff Atkinson (University of Windsor). We would also like to thank all of our moderators, Pierrette Buklis (CFDR Board), Marcia Cooper (Health Canada), Jenny Gusba (CFDR Board), Brenda Hartman (Brescia College), Paula Brauer (University of Guelph), Dawna Royall (DC), and MaryAnne Smith (DC), who kept our research presentation sessions on time during the conference. Finally, a special thank you to France Bertrand and Michelle Naraine at CFDR for their assistance and support throughout the review process. We enjoyed interacting with many of you at the oral research presentations as we highlighted the research findings from our dietetic colleagues across our country! Christina Lengyel, PhD, RD Chair, 2018 Early Bird Abstracts Review Committee Associate Professor Director of the Dietetics Program Food and Human Nutritional Sciences University of Manitoba Janis Randall Simpson, PhD, RD, FDC Chair, 2018 Late Breaking Abstracts Review Committee Professor Emerita University of Guelph Executive Director, CFDR

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"Alteration in adrenergic mechanisms in early and late stages of adriamycin cardiomyopathy *1Jiangang Tong, Pallab K. Ganguly, and Pawan K. Singal. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Center and Departments of Physiology and Anatomy, University of Manitoba, Winnipeg, Canada, R3E 0W3." Journal of Molecular and Cellular Cardiology 22 (March 1990): S23. http://dx.doi.org/10.1016/0022-2828(90)91378-k.

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"Inhibition of cardiac phospholipid N-methylation by oxygen free radicals *1M. Kaneko, G. Paolillo, S. Majumder, C. Ou, V. Panagia and N.S. Dhalla. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre and Departments of Physiology and Anatomy, University of Manitoba, Winnipeg, Canada R2H 2A6." Journal of Molecular and Cellular Cardiology 21 (April 1989): S179. http://dx.doi.org/10.1016/0022-2828(89)92038-5.

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"Stimulatory effect of catalytic subunit of cyclic AMP-dependent protein kinase on lipid methylation in isolated cardiac sarcolemma *1R. Vetter, V. Panagia, J. Dai, Y. Taira, N.S. Dhalla. Division of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, and Department of Physiology and Anatomy, Faculty of Medicine, University of Manitoba, Winnipeg, Canada." Journal of Molecular and Cellular Cardiology 21 (April 1989): S180. http://dx.doi.org/10.1016/0022-2828(89)92039-7.

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