Academic literature on the topic 'UNR'

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Journal articles on the topic "UNR"

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Woehler, Meredith L., Kristin L. Cullen-Lester, Caitlin M. Porter, and Katherine A. Frear. "Whether, How, and Why Networks Influence Men’s and Women’s Career Success: Review and Research Agenda." Journal of Management 47, no. 1 (October 1, 2020): 207–36. http://dx.doi.org/10.1177/0149206320960529.

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Substantial research has documented challenges women experience building and benefiting from networks to achieve career success. Yet fundamental questions remain regarding which aspects of men’s and women’s networks differ and how differences impact their careers. To spur future research to address these questions, we present an integrative framework to clarify how and why gender and networks—in concert—may explain career inequality. We delineate two distinct, complementary explanations: (1) unequal network characteristics (UNC) asserts that men and women have different network characteristics, which account for differences in career success; (2) unequal network returns (UNR) asserts that even when men and women have the same network characteristics, they yield different degrees of career success. Further, we explain why UNC and UNR emerge by identifying mechanisms related to professional contexts, actors, and contacts. Using this framework, we review evidence of UNC and UNR for specific network characteristics. We found that men’s and women’s networks are similar in structure (i.e., size, openness, closeness, contacts’ average and structural status) but differ in composition (i.e., proportion of men, same-gender, and kin contacts). Many differences mattered for career success. We identified evidence of UNC only (same-gender contacts), UNR only (actors’ and contacts’ network openness, contacts’ relative status), neither UNC nor UNR (size), and both UNC and UNR (proportion of men contacts). Based on these initial findings, we offer guidance to organizations aiming to address inequality resulting from gender differences in network creation and utilization, and we present a research agenda for scholars to advance these efforts.
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Boussadia, Oréda, Michael Niepmann, Laurent Créancier, Anne-Catherine Prats, François Dautry, and Hélène Jacquemin-Sablon. "Unr Is Required In Vivo for Efficient Initiation of Translation from the Internal Ribosome Entry Sites of both Rhinovirus and Poliovirus." Journal of Virology 77, no. 6 (March 15, 2003): 3353–59. http://dx.doi.org/10.1128/jvi.77.6.3353-3359.2003.

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ABSTRACT Translation of picornavirus RNAs is mediated by internal ribosomal entry site (IRES) elements and requires both standard eukaryotic translation initiation factors (eIFs) and IRES-specific cellular trans-acting factors (ITAFs). Unr, a cytoplasmic RNA-binding protein that contains five cold-shock domains and is encoded by the gene upstream of N-ras, stimulates translation directed by the human rhinovirus (HRV) IRES in vitro. To examine the role of Unr in translation of picornavirus RNAs in vivo, we derived murine embryonic stem (ES) cells in which either one (−/+) or both (−/−) copies of the unr gene were disrupted by homologous recombination. The activity of picornaviral IRES elements was analyzed in unr +/+, unr +/−, and unr −/− cell lines. Translation directed by the HRV IRES was severely impaired in unr −/− cells, as was that directed by the poliovirus IRES, revealing a requirement for Unr not previously observed in vitro. Transient expression of Unr in unr −/− cells efficiently restored the HRV and poliovirus IRES activities. In contrast, the IRES elements of encephalomyocarditis virus and foot-and-mouth-disease virus are not Unr dependent. Thus, Unr is a specific regulator of HRV and poliovirus translation in vivo and may represent a cell-specific determinant limiting replication of these viruses.
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Martinez-Useros, Javier, Nuria Garcia-Carbonero, Weiyao Li, Maria J. Fernandez-Aceñero, Ion Cristobal, Raul Rincon, Maria Rodriguez-Remirez, Aurea Borrero-Palacios, and Jesus Garcia-Foncillas. "UNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition." Journal of Clinical Medicine 8, no. 4 (April 25, 2019): 560. http://dx.doi.org/10.3390/jcm8040560.

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CSDE1 (cold shock domain containing E1) gene is located upstream of the N-RAS locus, and codes for an RNA-binding protein named Upstream of N-Ras (UNR). In cancer, CSDE1 has been shown to regulate c-Fos, c-Myc, Pten, Rac1, or Vimentin. UNR/CSDE1 has been studied in breast, melanoma, pancreatic and prostate cancer. Then, the aim of this study is to evaluate the role of CSDE1/UNR in colorectal cancer progression and maintenance of aggressive phenotype. We firstly evaluated UNR/CSDE1 expression in human colon cancer derived cell lines and patient samples. Subsequently, we performed functional experiments by UNR/CSDE1 downregulation. We also evaluated UNR/CSDE1 prognostic relevance in two independent sets of patients. Not only was UNR/CSDE1 expression higher in tumor samples compared to untransformed samples, but also in colonospheres and metastatic origin cell lines than their parental and primary cell lines, respectively. Downregulation of UNR/CSDE1 reduced cell viability and migration throughout a restrain of epithelial-to-mesenchymal transition and increases sensitivity to apoptosis. Interestingly, high UNR/CSDE1 expression was associated with poor prognosis and correlated positively with c-MYC expression in colorectal cancer samples and cell lines. Here, we show for the first time compelling data reporting the oncogenic role of UNR/CSDE1 in human colorectal cancer.
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Dinur, Maya, Rachel Kilav, Alin Sela-Brown, Helene Jacquemin-Sablon, and Tally Naveh-Many. "In Vitro Evidence that Upstream of N-ras Participates in the Regulation of Parathyroid Hormone Messenger Ribonucleic Acid Stability." Molecular Endocrinology 20, no. 7 (July 1, 2006): 1652–60. http://dx.doi.org/10.1210/me.2005-0333.

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Abstract Calcium and phosphate regulate PTH gene expression posttranscriptionally through the binding of trans-acting factors to a defined cis-acting instability element in the PTH mRNA 3′-untranslated region (UTR). We have previously defined AU-rich binding factor 1 as a PTH mRNA binding and stabilizing protein. We have now identified, by affinity chromatography, Upstream of N-ras (Unr) as another PTH mRNA 3′-UTR binding protein. Recombinant Unr bound the PTH 3′-UTR transcript, and supershift experiments with antibodies to Unr showed that Unr is part of the parathyroid RNA binding complex. Finally, because there is no parathyroid cell line, the functionality of Unr in regulating PTH mRNA levels was demonstrated in cotransfection experiments in heterologous human embryonic kidney 293 cells. Depletion of Unr by small interfering RNA decreased simian virus 40-driven PTH gene expression in human embryonic kidney 293 cells transiently cotransfected with the human PTH gene. Overexpression of Unr increased the rat full-length PTH mRNA levels but not a PTH mRNA lacking the terminal 60-nucleotide cis-acting protein binding region. Unr also stabilized a chimeric GH reporter mRNA that contained the rat PTH 63-nucleotide cis-acting element but not a truncated PTH element. Therefore, Unr binds to the PTH cis element and increases PTH mRNA levels, as does AU-rich binding factor 1. Our results suggest that Unr, together with the other proteins in the RNA binding complex, determines PTH mRNA stability.
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Akimoto, Takayoshi, Makoto Hara, Akihiko Morita, Shuichiro Uehara, and Hideto Nakajima. "Relationship between Nutritional Scales and Prognosis in Elderly Patients after Acute Ischemic Stroke: Comparison of Controlling Nutritional Status Score and Geriatric Nutritional Risk Index." Annals of Nutrition and Metabolism 77, no. 2 (2021): 116–23. http://dx.doi.org/10.1159/000515212.

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<b><i>Background/Aims:</i></b> Undernutrition is common in patients after acute ischemic stroke (AIS) and predicts poor clinical outcomes. We assessed the relationship between undernutrition and prognosis after AIS. <b><i>Methods:</i></b> We retrospectively assessed consecutively hospitalized AIS patients aged ≥65 years. A poor prognosis for patients after AIS was defined as a modified Rankin Scale (mRS) score of ≥3 at discharge. Nutritional status was evaluated based on the degree and risk of undernutrition as determined by the Controlling Nutritional Status (UND-CONUT) and Geriatric Nutritional Risk Index (UNR-GNRI) scores. <b><i>Results:</i></b> Among 218 patients (male, 62.8%; median age, 77 years), 81 had a poor prognosis. A significant correlation was found between UND-CONUT and UNR-GNRI scores (<i>p</i> &#x3c; 0.001, <i>r</i> = 0.433). Patients with a poor prognosis showed significant undernutrition based on UND-CONUT (<i>p</i> = 0.003) but not on UNR-GNRI (<i>p</i> = 0.218). Patients with undernutrition based on UND-CONUT showed poor outcomes: higher mRS scores at discharge, higher percentages of mRS scores of ≥2 and ≥3, and more complications associated with pneumonia. No significant differences were seen between cases with and without undernutrition risk based on UNR-GNRI. <b><i>Conclusion:</i></b> UND-CONUT appeared to be more useful than UNR-GNRI for predicting the prognosis of elderly patients with AIS at discharge.
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Anderson, Emma C., and Pól Ó. Catnaigh. "Regulation of the expression and activity of Unr in mammalian cells." Biochemical Society Transactions 43, no. 6 (November 27, 2015): 1241–46. http://dx.doi.org/10.1042/bst20150165.

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Unr (upstream of N-ras) is a post-transcriptional regulator of gene expression, essential for mammalian development and mutated in many human cancers. The expression of unr is itself regulated at many levels; transcription of unr, which also affects expression of the downstream N-ras gene, is tissue and developmental stage-dependent and is repressed by c-Myc and Max (Myc associated factor X). Alternative splicing gives rise to six transcript variants, which include three different 5′-UTRs. The transcripts are further diversified by the use of three alternative polyadenylation signals, which governs whether AU-rich instability elements are present in the 3′-UTR or not. Translation of at least some unr transcripts can occur by internal initiation and is regulated in a cell-cycle-dependent manner; binding of PTB (polypyrimidine tract-binding protein) and Unr to the 5′-UTR inhibits translation, but these are displaced by heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNPC1/C2) during mitosis to stimulate translation. Finally, Unr is post-translationally modified by phosphorylation and lysine acetylation, although it is not yet known how these modifications affect Unr activity.
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Anderson, Emma C., Sarah L. Hunt, and Richard J. Jackson. "Internal initiation of translation from the human rhinovirus-2 internal ribosome entry site requires the binding of Unr to two distinct sites on the 5′ untranslated region." Journal of General Virology 88, no. 11 (November 1, 2007): 3043–52. http://dx.doi.org/10.1099/vir.0.82463-0.

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Internal initiation of translation from the human rhinovirus-2 (HRV-2) internal ribosome entry site (IRES) is dependent upon host cell trans-acting factors. The multiple cold shock domain protein Unr and the polypyrimidine tract-binding protein have been identified as synergistic activators of HRV-2 IRES-driven translation. In order to investigate the mechanism by which Unr acts in this process, we have mapped the binding sites of Unr to two distinct secondary structure domains of the HRV-2 IRES, and have identified specific nucleotides that are involved in the binding of Unr to the IRES. The data suggest that Unr acts as an RNA chaperone to maintain a complex tertiary IRES structure required for translational competency.
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Roche, Rose, and Michael Bange. "Effects of Plant Density, Mepiquat Chloride, Early-Season Nitrogen and Water Applications on Yield and Crop Maturity of Ultra-Narrow Cotton." Agronomy 12, no. 4 (March 31, 2022): 869. http://dx.doi.org/10.3390/agronomy12040869.

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Research investigating row spacing in high-yielding, high-input cotton (Gossypium hirsutum L.) production systems has found higher lint yields but no maturity benefits using high plant density, 25 cm spaced ultra-narrow rows (UNR). Seven experiments comparing 38 cm UNR and conventionally spaced rows (100 cm) were conducted over three years to determine if changes in plant density or management could optimize yield and maturity in a high-input UNR cotton production system. Two of these experiments compared 25, 38 and 100 cm spaced rows under different intra-row plant density (12 to 36 plants m−2). Three experiments managed 38 cm UNR and 100 cm spaced rows separately and one had extra early application of nitrogen and water. Across the seven experiments there were no differences in lint yield or crop maturity for 38 cm UNR compared to conventionally spaced rows. The only significant response to changes in inter- or intra-row density or agronomic management was an 18% increase in handpicked lint yield in the 12 plants m−2 38 cm UNR treatment compared to the same plant density in 100 cm spaced rows in one of the two experiments. This stability of yield response across row spacings indicates that there is an opportunity to reduce seed rates whilst maintaining yields in high-input UNR systems. UNR cotton did not require any difference in mepiquat chloride or nitrogen management compared with conventionally spaced cotton, nor did extra early inputs of nitrogen or water, and we concluded that is likely that the current recommendations for mepiquat chloride or nitrogen nutrition in conventionally spaced systems are appropriate for managing high-input UNR cotton crops.
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Fernando Avendaño, Susana Copertari, and Candela Avendaño. "INVESTIGACIÓN, POLÍTICAS UNIVERSITARIAS DE FORMACIÓN DOCENTE Y CIUDADANÍA DIGITAL EN ENTORNOS VIRTUALES." Revista Científica Educ@ção 7, no. 11 (May 21, 2022): 1300–1310. http://dx.doi.org/10.46616/rce.v7i11.201.

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El trabajo que presentamos es una investigación interdisciplinaria, presentada ante la Secretaría de Ciencia y Tecnología de la Universidad Nacional de Rosario (UNR), (Argentina), radicada en el Instituto de Investigaciones de la Facultad de Humanidades y Artes (UNR), (Escuela de Cs de la Educación; Secretaría de Posgrado (Doctorado en Educación y Maestría Interinstitucional sobre Estudios en Construcción de Ciudadanía). Sustentada en el paradigma cuali-cuantitativo, con aportes del método etnográfico de trabajo de campo, tanto presencial como virtual (TAYLOR y BODGAN, 1987; GUBER, 2004; COPERTARI, 2021), desde el contexto de una Antropología de las políticas públicas (BALL, 1990; COPERTARI, 2021). Se focaliza en el estudio de una experiencia que se está llevando adelante en nuestra Universidad como Política Pública de Formación Docente en entornos virtuales (LITWIN, 1995), mediante la implementación de una Diplomatura, desarrollada en el Campus Virtual-UNR- SIED (Sistema Institucional de Educación a Distancia). Una política pública de Formación Docente a través de la "Diplomatura en Estudios Avanzados por Entornos virtuales de enseñanza y aprendizaje" (EVEA)". Se inició en el año 2021, con el propósito de brindar una formación a docentes de las 12 Facultades e Institutos Superiores de la (UNR), a fin de llevar adelante procesos de enseñanza y aprendizaje en otros formatos, además del tradicional de las clases presenciales. La iniciativa surge del Rectorado con la intención de poder dar respuestas a la crisis pandémica Covid 19, a las desigualdades educativas de todo tipo y a la exclusión, agudizadas en tiempos crisicos y críticos a nivel mundial. El objetivo fundamental consiste en analizar crítica y reflexivamente ¿cuál es la política académica y de gestión de la (UNR) en materia de educación a distancia (EaD)?, ya sea virtual o semipresencial. Desde la tecnología educativa y en el marco de la EaD se intenta indagar acerca de sus implicancias en la formación docente de cada unidad académica. Acercamos un análisis sobre el estado actual de los conocimientos sobre el tema, como etapa inicial de la investigación pensando en la centralidad de la inclusión educativa, cuando la virtualización de la enseñanza llegó para quedarse, casi con pretensiones universalistas (COPERTARI y LOPES NEVES, 2020).
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Ray, Swagat, Pól Ó. Catnaigh, and Emma C. Anderson. "Post-transcriptional regulation of gene expression by Unr." Biochemical Society Transactions 43, no. 3 (June 1, 2015): 323–27. http://dx.doi.org/10.1042/bst20140271.

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Unr (upstream of N-ras) is a eukaryotic RNA-binding protein that has a number of roles in the post-transcriptional regulation of gene expression. Originally identified as an activator of internal initiation of picornavirus translation, it has since been shown to act as an activator and inhibitor of cellular translation and as a positive and negative regulator of mRNA stability, regulating cellular processes such as mitosis and apoptosis. The different post-transcriptional functions of Unr depend on the identity of its mRNA and protein partners and can vary with cell type and changing cellular conditions. Recent high-throughput analyses of RNA–protein interactions indicate that Unr binds to a large subset of cellular mRNAs, suggesting that Unr may play a wider role in translational responses to cellular signals than previously thought.
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Dissertations / Theses on the topic "UNR"

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BOUSSADIA, OREDA. "Deletion du promoteur du gene unr murin par recombinaison homologue : etude de l'interference transcriptionnelle dans le locus unr / n-ras et du role biologique de la proteine unr." Paris 11, 1996. http://www.theses.fr/1996PA11T017.

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Abaza, Irina. "Drosophila UNR: a factor involved in the translational regulation of dosage compensation." Doctoral thesis, Universitat Pompeu Fabra, 2006. http://hdl.handle.net/10803/78125.

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Dosage compensation is a mechanism that equalizes the expression of X-linked genes in those organisms in which males and females differ in the number of X chromosomes. In Drosophila melanogaster, dosage compensation is achieved by up-regulating the transcription of the single male X chromosome. This effect is mediated by a chromatin remodeling complex known as the Male Specific Lethal (MSL) complex or Dosage Compensation Complex (DCC). In female flies, dosage compensation is inhibited primarily because of the translational repression of the mRNA encoding one of the DCC subunits, MSL-2, by the female-specific RNA binding protein Sex-lethal (SXL). To inhibit translation, SXL binds to poly(U) stretches present in both the 5’ and 3’ UTRs of msl-2 mRNA. Sequences adjacent to those SXL-binding sites in the 3´UTR are also required for translation inhibition and are bound by co-repression. In this thesis work, we have designed an affinity chromatography assay to isolate the putative co-repressor(s), and have identified the protein Upstream of N-ras (UNR). Drosophila UNR (dUNR) is an ubiquitous, conserved protein that contains 5 cold shock domains (CSD) and a glutamine- (Q) rich amino- terminal extension. We show that dUNR is a necessary co-factor for SXL-mediated msl-2 repression. SXL recruits dUNR to the 3’ UTR of msl-2 mRNA, imparting a sex-specific function to this ubiquitous protein. Domain mapping experiments indicate that dUNR interacts with SXL and msl-2 mRNA through CSD1, and that the domains for translation inhibition and SXL interaction can be distinguished. Our data indicate that the Q-rich domain, together with CSDs 1 and 2, plays an important role in translational repression, and suggest that factors in addition to dUNR and SXL are required for repression of msl-2 mRNA. Using a combination of UNR immunoprecipitation and microarray analysis, we have identified the mRNAs that are bound to dUNR in male and female flies. Our results suggest that dUNR is not only a novel regulator of dosage compensation, but also a general post-transcriptional regulator of gene expression.
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Dormoy-Raclet, Virginie. "Caractérisation fonctionnelle de la protéine Unr (Upstream of N-ras) : rôle dans la réponse au stress et identification de gènes régulés par Unr." Bordeaux 2, 2005. http://www.theses.fr/2005BOR21244.

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Nous nous intéressons au rôle de la protéine Unr(Upstream of N-Ras, ptotéine se liant à l'ARN, dans la réponse cellulaire aux radiations ionisantes. En effet, notre groupe a montré que des cellules souches embryonnaires (ES) de souris nulles pour Unr que nous avions isolées étaient plus résistantes aux radiations ionisantes que des cellules ES sauvages. Nous avons analysé les voies cellulaires modulées par Unr avant et après traitement par radiations ionisantes afin d'identifier les gènes cibles de la protéine Unr. Les résultats obtenus convergent vers le modèle d'un rôle de protéines impliquées dans la maturation des ARN messagers dans les mécanismes de sensibilité / résistance aux agents antitumoraux
We are interested in the role of the protein Unr (Upstream of N-Ras), an RNA-binding protein, in the cellular response to ionizing radiations. Indeed, our group showed that mouse embryonic stem cells cells (ES) null for which we had isolated were more resistant to ionizing radiations than wild type ES cells. We analyzed the cellular ways modulated by Unr before and after IR in order to identify target genes of the Unr protein. The results obtained converge towards the model of a role of proteins implied in the maturation of the mRNA in the mechanisms of sensitivity/resistance to the antitumor agents
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Militti, Cristina 1982. "Drosophila UNR regulates dosage compensation through modulation of RNA-protein interactions." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/283476.

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En Drosophila, el desequilibrio en cuanto al contenido de genes ligados al cromosoma X entre hembras (XX) y machos (XY) es corregido mediante la duplicación de la transcripción del único cromosoma X del macho. Este proceso, llamado compensación de dosis, es mediado por un ensamblaje molecular compuesto por al menos cinco proteínas (MSL1, MSL2, MSL3, MLE y MOF) y dos RNAs largos no codificantes (roX1 y roX2), llamado complejo de compensación de dosis (DCC). La compensación de dosis requiere dos condiciones fundamentales: el reconocimiento específico del cromosoma X por el DCC, y la restricción del proceso a moscas macho. La proteína de unión a RNA Upstream-of-N-Ras (UNR) está implicada en la consecución de ambas condiciones, y aquí hemos estudiado los mecanismos moleculares por los que UNR actúa. Hemos encontrado que, en machos, UNR promueve la compensación de dosis facilitando la asociación de roX2 a MLE, necesaria para una correcta formación del DCC y para su unión al cromosoma X. En hembras, UNR inhibe la compensación de dosis, al menos en parte, promoviendo la unión de SXL al extremo 3’ UTR del mRNA que codifica para msl2, lo que resulta en represión de la traducción de msl2 e inhibición de la formación del DCC.
In Drosophila, the imbalance in X-linked gene content between females (XX) and males (XY) is restored through the 2-fold hypertranscription of the single male X-chromosome. This process, which is called dosage compensation, is mediated by the action of the dosage compensation complex (DCC), a ribonucleoprotein assembly composed of at least five proteins (MSL1, MSL2, MSL3, MLE and MOF) and two long non-coding RNAs (roX1 and roX2). Two features are essential for correct dosage compensation: the specific recognition of the X-chromosome by the DCC and the confinement of the DCC function to the male organism. The RNA binding protein Upstream of N-ras (UNR) is involved in the regulation of these two processes and we have dissected the molecular mechanisms by which this regulation occurs. We have found that, in male flies, UNR promotes dosage compensation by facilitating the association of roX2 with MLE, which is required for correct DCC formation and X-chromosome targeting. In female flies, UNR represses dosage compensation in part by enhancing the binding of SXL to the 3’UTR of msl2 mRNA, thus ensuring tight msl2 translational repression and subsequent inhibition of DCC formation.
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Ó, Catnaigh Pól. "An investigation into the RNA-binding protein UNR and its interactors." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/91504/.

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Recent work linked the RNA-binding protein UNR to a number of human pathologies although little is currently known about how UNR functions in human cells. This thesis aims to elucidate how UNR functions by, among other things, discovering novel UNR-interacting proteins and transcripts and proteins that are differentially expressed in the presence or absence of UNR. It is shown that UNR levels decrease with increasing cell confluency in cultured HeLa cells but that they increase with increasing confluency in the wild type TP53-containing U2OS cell line. UNR is shown to colocalise to stress granules with TP53 in arsenite-stressed HeLa cells. A number of novel UNR-interacting proteins were discovered in three cell lines (HeLa, U2OS and SaOS-2), including HUWE1, NARR, SQSTM1 and LDB1. GO-term overrepresentation analysis confirmed that UNR is an RNA-binding protein as ‘RNA binding’ and ‘poly(A) RNA binding’ were the top two overrepresented molecular function GO terms by p-value across each of the cell types. Less expected overrepresented GO terms pertained to selenium metabolism and the extracellular exosome. There was no evidence for conservation of UNR-interacting transcripts across the cell types but there were some similar significantly overrepresented GO terms among the respective UNR-interacting transcripts. These included terms pertaining to RNA and the nucleus. The most significant UNR-interacting transcript in HeLa cells was PABPC1 and that the PABP protein was also significantly upregulated following UNR knockdown in HeLa cells. ‘Poly (A) RNA binding’ was a significantly overrepresented GO term among proteins differentially regulated following UNR knockdown in HeLa and U2OS cells. ‘Adherens junction’ was another significantly overrepresented GO term using proteins that were higher in abundance in siUNR-treated HeLa cells and either higher or lower in abundance in either arsenite-stressed or unstressed U2OS cells. UNR was observed at cell-cell junctions in HeLa and U2OS cells by immunofluorescence microscopy.
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Zhang, Rui. "Molecular Analysis of Pcp2/L7 3'UTR and Its Putative Binding Proteins: Unr and Vps36." Columbus, Ohio : Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1213363637.

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Inglés, Ferrándiz Marta 1989. "Post-transcriptional regulation by UNR : insights into histone mRNA metabolism and cellular senescence." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/665819.

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In this thesis, we have been studying the role of UNR, and RNA-binding protein that regulates translation and/or stability of its targets. The functional relevance of UNR was studied in two different molecular contexts: histone mRNA metabolism and cellular senescence. UNR strongly binds to the 3’ untranslated region very close to the stem-loop. Previous data from the laboratory suggested that UNR stabilizes these mRNAs. As UNR is localized mainly in the cytoplasm, we hypothesized that it might be controlling post-transcriptional events. However, after several experimental trials in vitro and in cellulo we did not reach into any conclusion of how UNR might be influencing histone mRNAs metabolism. For this reason, we undertook an additional project. We found a novel role of UNR in oncogene-induced senescence (OIS) and determined cell-autonomous tumour suppressive properties in this context. In addition, we suspect that UNR influences the secretion of senescence associated secretory phenotype (SASP) of senescent cells, exerting tumour suppressive properties also in non-autonomous manner. Further experiments are needed to fully understand the contribution of UNR in OIS.
En esta tesis, hemos estudiando el papel de UNR, una proteína de unión al ARNm, que regula la estabilidad y/o traducción de los ARNms a los que se une. Se ha estudiado la relevancia funcional de UNR en dos contextos moleculares diferentes: el metabolismo de los ARNm de histona y la senescencia celular. UNR se une fuertemente a la región 3 ' no traducida muy cerca de una estructure secundaria importante (llamada stem-loop). Resultados anteriores del laboratorio sugirieron que UNR estabiliza estos mRNAs. Dado que UNR es una proteína principalmente citoplasmática, hipotetizamos que estaría controlando procesos post-transcripcionales. Sin embargo, tras varios experimentos in vitro e in cellulo, no hemos podido llegar a ninguna conclusión de cómo UNR influye en el metabolismo de estos transcritos. Por esta razón, emprendimos un proyecto adicional. Hemos hallado una nueva función de UNR en el proceso de senescencia celular inducida por oncogenes (OIS). Hemos podido determinar que UNR actúa como una proteína supresora de tumores en las propias células. Además, nuestros experimentos sugieren que UNR influye en la secreción de moléculas relacionadas con células senescentes (factores SASP), produciendo también propiedades supresoras de tumores en las células de alrededor. Se necesitan más experimentos para comprender completamente la contribución de UNR en OIS.
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Henning, Jessica L. "Stormwater and flooding on the UNR campus a current and future modeling assessment /." abstract and full text PDF (UNR users only), 2009. http://0-gateway.proquest.com.innopac.library.unr.edu/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1472956.

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Taha, Nedal. "Interaction du domaine nucleocapside de la polyprotéine Gag du VIH-1 avec la protéine cellulaire Unr : implication sur la traduction IRES-dépendante du virus." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ028/document.

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La protéine de nucléocapside (NC) du virus de l’immunodéficience humaine (VIH-1) joue de nombreux rôles dans les phases précoce et tardive de l’infection. La NC est une protéine à deux doigts de zinc, chaperonne des acides nucléiques. Nous avons cherché de nouveaux partenaires cellulaires de la NCp7 et identifié une protéine de liaison aux ARNs, Upstream of N-ras (Unr), dont l’interaction avec Gag et NCp7 a été confirmée. L’interaction entre Gag et Unr est dépendante de l’ARN et médiée par le domaine NC. Unr est une ITAF (IRES transacting factor) régulant la traduction médiée par plusieurs IRESs cellulaires et viraux. L’ARN génomique du VIH-1 possède deux IRESs dont un localisé dans la région non traduite en 5’ qui permet aux ARNm viraux de conserver un fort niveau de traduction lorsque la traduction coiffe-dépendante de la cellule est affaiblie par l’arrêt du cycle viral induit par l’infection. En utilisant un système de dual luciférase, nous avons montré qu’Unr est une ITAF dont la surexpression stimule l’IRES VIH-1. Des mutations ponctuelles de cet IRES, dans un motif consensus de liaison à Unr, altèrent à la fois l’activité de l’IRES et sa réponse à Unr suggérant que l’activité IRES dépend fortement de Unr. L’effet d’Unr sur l’IRES est inhibé par la surexpression de NCp7 mais pas par celle de Gag dont l’effet stimulateur sur l’IRES est additif de celui d’Unr suggérant un rôle d’Unr différent dans les phases précoce et tardive de l’infection. Pour finir, le knockdown de l’expression d’Unr entraîne une diminution significative de l’infection par un pseudovirus non réplicatif soulignant l’implication fonctionnelle d’Unr dans la phase précoce
The Human Immunodeficiency Virus-1 (HIV-1) nucleocapsid protein (NC), as a mature protein (NCp7) or as a domain of the polyprotein Gag, plays several important roles in both the early and late phase of the infection. NC is a nucleic acid chaperone protein with two zinc fingers. We searched for new cellular protein partners of NCp7 and identified the RNA binding protein Unr, Upstream of N-ras, whose interaction with both Gag and NCp7 was confirmed. Unr interaction with Gag is RNA dependent and mediated by its NC domain. Unr is an ITAF (IRES trans-acting factor) regulating the translation driven by several IRESs. The HIV-1 genomic mRNA harbors two IRESs elements: one of them found within the HIV-1 5’-Untranslated region drives HIV-1 mRNA translation when the cap-dependent translation is diminished due to the infection-induced cell cycle arrest. Using a dual luciferase assay, Unr was shown to act as an ITAF, increasing the HIV-1 IRES dependent translation. Point mutations of the HIV-1 IRES in a consensus Unr binding motif were found to alter both the IRES activity and its activation by Unr suggesting a strong dependency of the IRES on Unr. Unr stimulation effect is furthermore counteracted by NCp7, but not by Gag overexpression, which increases the IRES activity in an additive manner to Unr suggesting a differential Unr effect on the early and late phases of the infection. Finally, knockdown of Unr in HeLa cells leads to a decline in infection by a non-replicative lentivector proving its functional implication in the early phase
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Patalano, Solenn. "The translation regulator UNR performs opposite sex-specific functions for dosage compensation in Drosophila." Nice, 2008. http://www.theses.fr/2008NICE4099.

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La compensation de dose est le processus qui permet d’égaliser le niveau d’expression des gènes liés au X entre les mâles et les femelles. Chez la Drosophile, ce processus a lieu par le doublement de la transcription des gènes grâce à la fixation du complexe de compensation de dose sur le chromosome X des mâles. Chez les femelles, la traduction de l’ARN msl-2, codant pour une sous unité du complexe, est réprimée par la protéine SXL empêchant ainsi la formation du complexe. Pour élucider les mécanismes moléculaires de cette répression, des expériences de traduction in vitro ont permis la mise en évidence d’une région requise pour l’inhibition de msl-2 reconnue par UNR, un co-facteur de SXL, préalablement identifié comme impliqué dans le mécanisme de répression de la compensation de dose chez les femelles. L’étude in vivo d’un mutant hypomorphe de UNR a montré qu’une partie de msl-2 était transcrite chez les femelles mutantes, capable ainsi de former le complexe de compensation sur les sites d’affinité des chromosomes X. Curieusement, l’ensemble des membres du complexe était cependant faiblement recruté sur le chromosome X des mutants mâles dont la chromatine était anormalement relaxée. En inactivant la fonction de UNR par RNAi sur des cellules mâles en culture, ces phénotypes ont été reproduits sans que la distribution des composants du complexe ne soit perturbée. Ces résultats ont permis de découvrir une nouvelle fonction pour UNR chez la Drosophile qui, en participant à l’inhibition de la compensation de dose par la répression de msl-2 chez les femelles, agit de manière opposée chez les males en contribuant à l’assemblage du DCC sur le chromosome X
Dosage compensation is the process by which the expression levels of X-linked genes are equalized between males and females. In Drosophila, binding of the dosage compensation complex to the single X chromosome of males causes a twofold increase of gene expression levels on this chromosome, thereby achieving the same level of expression as in females. In female flies, in contrast, the complex cannot be assembled because of the translational repression of one of its subunits, MSL2, by the binding of the female specific protein, SXL, to its RNA untranslated region. To understand the molecular mechanisms of msl-2 translational repression, in vitro translation experiments have identified a region necessary for msl-2 inhibition where UNR, a SXL co-factor, can indeed bind, highlighting its importance for dosage compensation repression in female flies. Strong evidence in support of such a function for UNR was provided by an in vivo study of a UNR hypomorphic mutant. Despite the low levels of MSL2 in mutant females, they were sufficient for the assembly and binding of the dosage compensation complex on the X “high affinity sites”. Curiously, in mutant males, the complex was weakly recruited to the single X chromosome where X chromatin was highly decondensed. RNAi inactivation of UNR in cultured male cells reproduced this phenotype without affecting the distribution of the complex components suggesting a major role for UNR in dosage compensation in males effected through chromatin regulation. Taken together, these observations uncover dual, sex-specific functions of UNR in X chromosome dosage compensation: repressing msl-2 expression in female flies while promotion DCC recruitment in males
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Books on the topic "UNR"

1

(Firm), UNR-Rohn Manufacturing. UNR-Rohn Manufacturing, Peoria Illinois. [Atlanta, Ga.?]: U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1994.

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I︠U︡rkova, Halyna. Kam'i︠a︡net︠s︡ʹ--ostanni︠a︡ stolyt︠s︡i︠a︡ UNR: Putivnyk. Kam'i︠a︡net︠s︡ʹ-Podilʹsʹkyĭ: PP "Medobory-2006", 2011.

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Koli︠a︡nchuk, Oleksandr. Internowani żołnierze armii UNR w Kaliszu 1920-1939. Kalisz: [OLIR], 1995.

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Rudnycʹkyj, Jaroslav B. V 65-richchi︠a︡ ekzyli︠u︡ uri︠a︡du UNR, 1920-1985. Ottawa, Ont., Canada: Pub. by UMMAN and Ukrainian Language Association, 1985.

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Nadii︠a︡, Myronet︠s︡, Instytut ukraïnsʹkoï arkheohrafiï ta dz︠h︡ereloznavstva im. M.S. Hrushevsʹkoho., and T︠S︡entralʹnyĭ derz︠h︡avnyĭ arkhiv vyshchykh orhaniv vlady ta upravlinni︠a︡ Ukraïny., eds. Nadzvychaĭna dyplomatychna misii︠a︡ UNR u Hret︠s︡ii (1919-1920). Kam'i︠a︡net︠s︡ʹ-Podilʹsʹkyĭ: Abetka, 2006.

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Pyz͡hyk, A. M. Kulʹturno-prosvitni͡a dii͡alʹnistʹ uri͡adu UNR v period Dyrektoriï. Kyïv: Chetverta khvyli͡a, 1998.

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Rudnycʹkyj, Jaroslav B. V 65-richchi͡a︡ ekzyli͡u︡ uri͡a︡du UNR, 1920-1985. Ottawa, Ont., Canada: Pub. by UMMAN and Ukrainian Language Association, 1985.

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Shulʹhyn, Oleksander. Bez terytoriï: Ideolohii͡a︡ ta chyn uri͡a︡du UNR na chuz͡h︡yni. Kyïv: I͡U︡rinkom Inter, 1998.

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Andrusyshyn, B. I. T͡S︡erkva v Ukraïnsʹkiĭ Derz͡h︡avi 1917-1920 rr.: Doba Dyrektoriï UNR. Kyïv: "Lybidʹ", 1997.

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Rudnycʹkyj, Jaroslav B. DT︠S︡ UNR v ekzyli miz︠h︡ 1941 i 1991/2 rokamy. 2nd ed. Ottava: Vydanni︠a︡ arkhivhoho komitetu UNR, 1994.

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Book chapters on the topic "UNR"

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Liu, Pinghua, Jason J. Millership, Lichun Li, David P. Giedroc, and Julian L. Leibowitz. "A Previously Unrecognized Unr Stem-Loop Structure in the Coronavirus 5’ Untranslated Region Plays a Functional role in Replication." In Advances in Experimental Medicine and Biology, 25–30. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-33012-9_3.

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Krebs, Marcel, Roger Mäder, and Tanya Mezzera. "Einleitung." In Soziale Arbeit und Sucht, 21–38. Wiesbaden: Springer Fachmedien Wiesbaden, 2020. http://dx.doi.org/10.1007/978-3-658-31994-6_1.

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ZusammenfassungDie tiefe Überzeugung, dass es uns nur dann gut gehen kann als Gesellschaft und Staat, wenn für das Wohlergehen und für Perspektiven auch für die Verletzlichen unter uns gesorgt ist, brachte mich zur Sozialen Arbeit. Die Präambel unserer Bundesverfassung beinhaltet, dass «…die Stärke des Volkes sich misst am Wohl der Schwachen» – diesem Grundwert mit Taten zu folgen, motiviert mich auch heute noch täglich. Die Thematik Sucht zieht sich durch meinen beruflichen Werdegang.
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Messerle, Robert, Jonas Schreyögg, and Ferdinand M. Gerlach. "Patientenorientierte Notfallsteuerung." In Krankenhaus-Report 2021, 43–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62708-2_3.

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Zusammenfassung Zusammenfassung Der Referentenentwurf zur Notfallversorgung wurde kurz vor einer der größten Krisen der Bundesrepublik veröffentlicht. Strukturelle Probleme des deutschen Gesundheitswesens wurden in der Krise besonders sichtbar und mussten quasi über Nacht zumindest provisorisch gelöst werden. Schon zuvor legten steigende Fallzahlen und eine weitgehend fehlende Steuerung die Probleme der Notfallversorgung offen. Eine grundlegende Strukturreform zur längerfristigen Behebung der verschiedenen Defizite erscheint einmal mehr notwendig, wurde aber vom Gesetzgeber zunächst vertagt. Der Sachverständigenrat stellte dazu bereits 2018 umfassende Empfehlungen vor, welche hier vorgestellt und punktuell ergänzt werden. Das Leitbild sind sektorenübergreifend koordinierte, klar abgestufte Versorgungspfade. In Integrierten Leitstellen (ILS) beurteilen erfahrene Fachkräfte rund um die Uhr die Behandlungsdringlichkeit der Anrufer und lenken die Versorgung in bedarfsgerechte und effiziente Strukturen. Ebenfalls rund um die Uhr erreichbare Integrierte Notfallzentren (INZ) stellen an qualitativ besonders geeigneten Kliniken den ersten Anlaufpunkt dar. Die weitere Behandlung erfolgt aus einer Hand, ambulant oder stationär.
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"Unr-interacting protein." In Encyclopedia of Cancer, 3847. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_10006.

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"Unrip: Unr-interacting Protein." In Encyclopedia of Cancer, 4737. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_102397.

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"3. The UNR, Radical Socialists, and Warlords." In Propaganda in Revolutionary Ukraine, 73–126. University of Toronto Press, 2019. http://dx.doi.org/10.3138/9781487530693-005.

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Zhang, Ming. "Ultra High Frequency SINC and Trigonometric Higher Order Neural Networks for Data Classification." In Advances in Computational Intelligence and Robotics, 113–53. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0063-6.ch005.

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This chapter develops a new nonlinear model, Ultra high frequency SINC and Trigonometric Higher Order Neural Networks (UNT-HONN), for Data Classification. UNT-HONN includes Ultra high frequency siNc and Sine Higher Order Neural Networks (UNS-HONN) and Ultra high frequency siNc and Cosine Higher Order Neural Networks (UNC-HONN). Data classification using UNS-HONN and UNC-HONN models are tested. Results show that UNS-HONN and UNC-HONN models are better than other Polynomial Higher Order Neural Network (PHONN) and Trigonometric Higher Order Neural Network (THONN) models, since UNS-HONN and UNC-HONN models can classify the data with error approaching 0.0000%.
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"Data Classification Using Ultra-High Frequency SINC and Trigonometric Higher Order Neural Networks." In Emerging Capabilities and Applications of Artificial Higher Order Neural Networks, 303–45. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-3563-9.ch007.

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This chapter develops a new nonlinear model, ultra high frequency sinc and trigonometric higher order neural networks (UNT-HONN), for data classification. UNT-HONN includes ultra high frequency sinc and sine higher order neural networks (UNS-HONN) and ultra high frequency sinc and cosine higher order neural networks (UNC-HONN). Data classification using UNS-HONN and UNC-HONN models are tested. Results show that UNS-HONN and UNC-HONN models are more accurate than other polynomial higher order neural network (PHONN) and trigonometric higher order neural network (THONN) models, since UNS-HONN and UNC-HONN models can classify data with error approaching 10-6.
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Zhvanko, Liubov, and Oleksiy Nestulya. "Ukrainian assistance to refugees during the First World War1." In Europe on the Move. Manchester University Press, 2017. http://dx.doi.org/10.7228/manchester/9781784994419.003.0006.

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The Ukrainian lands became an epicentre of the movement of refugees who were assisted by a range of organisations. This chapter considers the role of governmental bodies in the Russian Empire and the new entities that appeared on Ukrainian territory following the February 1917 Revolution: the Ukrainian Central Rada, and the Ukrainian National Republic (UNR). It discusses the developing framework and implementation of public policy in relation to refugees, the activity of local government and non-governmental organisations which supported refugees. The chapter considers refugees’ life in Ukraine in 1914-18. During the peace negotiations in Brest-Litovsk in February 1918, Ukrainian delegates took the initiative in organizing the re-evacuation of refugees; the agreement between Ukraine and Austro- Hungarian, German, Polish and Russian representatives concerning repatriation was an early example of inter-governmental regulation of a new humanitarian problem.
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Biolatto, Renato Enrique, Raúl Alberto Roque Vallone, Carla Paola Vallone, and Andrés Zenón Bassi. "LA FORMACIÓN SOCIAL DE ALUMNOS DE LA FACULTAD DE CIENCIAS VETERINARIAS, UNR." In Referências, Métodos e Tecnologias Atuais na Medicina Veterinária, 86–98. Atena Editora, 2021. http://dx.doi.org/10.22533/at.ed.83321090212.

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Conference papers on the topic "UNR"

1

Lampe, Sebastian, Thilo Brauß, Michael Kunze, Anica Scholz, Sofia Winslow, Bernhard Brüne, and Tobias Schmid. "Abstract B09: hnRNPA1 is a regulator of UNR IRES activity." In Abstracts: AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; October 27-30, 2016; San Francisco, CA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.transcontrol16-b09.

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Furrer, Jonas, Koji Kamei, Chandraprakash Sharma, Takahiro Miyashita, and Norihiro Hagita. "UNR-PF: An open-source platform for cloud networked robotic services." In 2012 IEEE/SICE International Symposium on System Integration (SII 2012). IEEE, 2012. http://dx.doi.org/10.1109/sii.2012.6427281.

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Frese, M. H., S. D. Frese, and V. Makhin. "Plasma formation in MHD simulations of the UNR Megagauss Experiment using MACH2." In 2009 IEEE 36th International Conference on Plasma Science (ICOPS). IEEE, 2009. http://dx.doi.org/10.1109/plasma.2009.5227529.

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Petkov, E. E., M. E. Weller, A. S. Safronova, V. L. Kantsyrev, A. A. Esaulov, I. Shrestha, G. C. Osborne, et al. "Extreme ultraviolet spectroscopy of CU cylindrical wire arrays on zebra at UNR." In 2013 IEEE 40th International Conference on Plasma Sciences (ICOPS). IEEE, 2013. http://dx.doi.org/10.1109/plasma.2013.6633224.

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Kantsyrev, V. L., A. S. Safronova, I. Shrestha, J. J. Moschella, V. V. Shlyaptseva, K. A. Schultz, W. Cline, et al. "X-ray generation from gas-puff jets irradiated by UNR Leopard laser." In 2014 IEEE 41st International Conference on Plasma Sciences (ICOPS) held with 2014 IEEE International Conference on High-Power Particle Beams (BEAMS). IEEE, 2014. http://dx.doi.org/10.1109/plasma.2014.7012502.

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Cui, Jia-Jia, Lei-Yun Wang, and Ji-Ye Yin. "Abstract 1407: Translational regulation of RPA2 via IRES by UNR and eIF3a." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1407.

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Gebauer, Fatima. "Abstract IA08: Role of the RNA binding protein UNR/CSDE1 in cancer progression." In Abstracts: AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; October 27-30, 2016; San Francisco, CA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.transcontrol16-ia08.

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Stafford, A., A. S. Safronova, V. L. Kantsyrev, M. E. Weller, V. V. Shlyaptseva, P. Wiewior, I. Shrestha, G. C. Osborne, S. F. Keim, and A. S. Chuvatin. "Analysis of K-shell HED plasmas in X-pinch and laser experiments at UNR." In 2014 IEEE 41st International Conference on Plasma Sciences (ICOPS) held with 2014 IEEE International Conference on High-Power Particle Beams (BEAMS). IEEE, 2014. http://dx.doi.org/10.1109/plasma.2014.7012507.

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Stafford, A., A. S. Safronova, V. L. Kantsyrev, A. A. Esaulov, M. E. Weller, G. C. Osborne, I. Shrestha, et al. "Analysis of Al precursor wire array experiments on the 1 MA zebra generator at UNR." In 2013 IEEE 40th International Conference on Plasma Sciences (ICOPS). IEEE, 2013. http://dx.doi.org/10.1109/plasma.2013.6633225.

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Safronova, A. S., V. L. Kantsyrev, A. A. Esaulov, M. E. Weller, V. V. Shlyaptseva, A. Stafford, S. F. Keim, et al. "Time evolution of Z-pinch dynamics and radiative characteristics of wire arrays on zebra at UNR." In 2011 IEEE 38th International Conference on Plasma Sciences (ICOPS). IEEE, 2011. http://dx.doi.org/10.1109/plasma.2011.5993089.

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Reports on the topic "UNR"

1

Li, Qizhen. FinalReport-DOE BES DMSE-UNR-QLi. Office of Scientific and Technical Information (OSTI), May 2014. http://dx.doi.org/10.2172/1130472.

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Kreher, Seth Emerich, and Christopher L. Rousculp. UNR ETI Computational Investigation (Year 2). Office of Scientific and Technical Information (OSTI), June 2020. http://dx.doi.org/10.2172/1635497.

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Loisel, Guillaume Pascal. z3308 z3309 photoionized Fe spectra and z3147 satire SS spectrum for Ryan Childers (UNR). Office of Scientific and Technical Information (OSTI), March 2020. http://dx.doi.org/10.2172/1604874.

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Loisel, Guillaume Pascal. October 2015 ZAPP shot series summary of collected data to be transferred to UNR and WVU. Office of Scientific and Technical Information (OSTI), December 2015. http://dx.doi.org/10.2172/1233623.

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Loisel, Guillaume Pascal. ZAPP20a shots z3459 z3460 z3461 and z3462. Ride-along Z data on LOS 330 for UNR university collaborators. Office of Scientific and Technical Information (OSTI), March 2020. http://dx.doi.org/10.2172/1606629.

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Liedhegener, Antonius, Gert Pickel, Anastas Odermatt, Alexander Yendell, and Yvonne Jaeckel. Wie Religion 'uns' trennt - und verbindet: Befunde einer Repräsentativbefragung zur gesellschaftlichen Rolle von religiösen und sozialen Identitäten in Deutschland und der Schweiz 2019. Leipzig University, November 2019. http://dx.doi.org/10.36730/rtv.2019.

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Krieger-Lamina, Jaro, ed. Wenn Algorithmen f�r uns entscheiden: Chancen und Risiken der k�nstlichen Intelligenz. Vienna: self, 2020. http://dx.doi.org/10.1553/10.3218/4002-9.

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Quat, M., B. Turner, R. Debicki, and P. Thurston. Temiskaming Shores : une plaine agricole, des diamants et un rift. Natural Resources Canada/CMSS/Information Management, 2015. http://dx.doi.org/10.4095/329921.

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Beltrán, José, Fernando Osvaldo Esteban, Daniel Gabaldón Estevan, Joan Carles Bernard i Garcia, Ignacio Martínez Morales, Juan Pecourt Gracia, and Ferran Colom Ortiz. Un estudio sobre los jóvenes de Valencia : una nueva aproximación sociológica. Universitat de València, 2012. http://dx.doi.org/10.7203/10550.25747.

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Misas A., Martha, Enrique Antonio López-Enciso, and Luis Fernando Melo-Velandia. La inflación desde una perspectiva monetaria: un modelo P* para Colombia. Bogotá, Colombia: Banco de la República, October 1999. http://dx.doi.org/10.32468/be.133.

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