Academic literature on the topic 'Unsubstituted β-lactam'

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Journal articles on the topic "Unsubstituted β-lactam"

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Gallagher, Timothy, Sylvie Sanchez, John H. Bateson, and Peter J. O'Hanlon. "Thiocarbonyl-based 1,3-dipolarophiles for the synthesis of C(2)-unsubstituted penems." Pure and Applied Chemistry 77, no. 12 (2005): 2033–40. http://dx.doi.org/10.1351/pac200577122033.

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The azomethine ylid strategy for β-lactam synthesis, which involves the fragmentation of a β-lactam-based oxazolidinone to give a carboxylated azomethine ylid, has been extended to the C(2)-unsubstituted penem scaffold associated with C(6)-exoalkylidene penems. This involved the use of S-methyl dithioformate as a reactive 1,3-dipolarophile, which was most effectively employed by initial trapping with cyclopentadiene and subsequent regeneration of S-methyl dithioformate via a retro Diels-Alder reaction in the presence of the requisite oxazolidinone. This provided access to the penam scaffold, a
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Ram, Naresh Yadav, Banik Indrani та Krishna Banik Bimal. "Microwave-mediated synthesis of 3-unsubstituted β-lactams with aqueous trimethylborane". Journal of Indian Chemical Society Vol. 95, Nov 2018 (2018): 1381–84. https://doi.org/10.5281/zenodo.5652771.

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Department of Chemistry, Faculty of Engineering &amp; Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh, India Department of Chemistry, University of Texas-Pan American,1201 W. University Dr., Edinburg, TX 78539, USA The University of Texas M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd, Houston, TX 77030, USA Current Address: Community Health System of South Texas, 3135 South Sugar Road, Edinburg, TX 78539, USA E-mail: bimalbanik10@gmail.com, bimal.banik@chsst.org <em>Manuscript received 03 October 2018, accepted 01 Novem
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M., S. MANHAS, M. BHAWAL B., B. SHANKAR B. та K. BOSE AJAY. "Stereocontrolled Synthesis of β-Lactams from Amidomalonates : Intermediates for Thienamycin, Carpetimycin and Analogs". Journal of Indian Chemical Society Vol. 62, Nov 1985 (1985): 891–98. https://doi.org/10.5281/zenodo.6325221.

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Department of Chemistry and Chemical Engineering, Stevens Institute of Technology, Hoboken, New Jersey 07080, U.S.A. Complete stereocontrol of<em> &beta;</em>-lactam formation can be achieved by the intra-mole&shy;cular cyclisation of the epoxide of an <em>N</em>-acroylaminomalonate. The <em>&beta;</em>-lactam so obtained is fused with a lactone ring derived from one of the ester groups of the malo&shy;nate and the carbinol side chain generated by the sterospecific opening of the epoxide ring. Selective hydrolysis of the lactone group leads to a <em>trans &beta;</em>-lactam ; selective decarbo
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Wolfe, Saul, та Tova Hoz. "A semiempirical molecular orbital study of the methanolysis of complex azetidinones. A combined MM and QM analysis of the interaction of Δ2- and Δ3-cephems with the penicillin receptor". Canadian Journal of Chemistry 72, № 4 (1994): 1044–50. http://dx.doi.org/10.1139/v94-132.

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The semiempirical molecular orbital procedures MINDO/3, MNDO, MNDO/M, AM1, and PM3 have been used to examine possible mechanisms and modes of attack of methanol on penam, the bicyclic ring system of penicillin. These mechanisms include a one-step process in which C—O bond formation from the convex face of the molecule and proton transfer to the β-lactam nitrogen are concerted with the cleavage of the N—C(O) bond (the N-protonated pathway), and two O-protonated pathways, viz., addition to the β-lactam carbonyl group from the convex face and from the concave face of the bicyclic ring system. Onl
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Shankar, B. B., M. P. Kirkup, S. W. McCombie, J. W. Clader та A. K. Ganguly. "Synthesis of an optically pure 3-unsubstituted β-lactam using an asymmetric Reformatsky reaction and its conversion to cholesterol absorption inhibitors". Tetrahedron Letters 37, № 24 (1996): 4095–98. http://dx.doi.org/10.1016/0040-4039(96)00764-2.

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SHANKAR, B. B., M. P. KIRKUP, S. W. MCCOMBIE, J. W. CLADER та A. K. GANGULY. "ChemInform Abstract: Synthesis of an Optically Pure 3-Unsubstituted β-Lactam Using an Asymmetric Reformatsky Reaction and Its Conversion to Cholesterol Absorption Inhibitors." ChemInform 27, № 37 (2010): no. http://dx.doi.org/10.1002/chin.199637150.

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Dugat, Denise, George Just та Soumya Sahoo. "β-Lactams. XII.: A study of the synthesis of N-unsubstituted β-lactams, and of 4-styryl monobactams". Canadian Journal of Chemistry 65, № 1 (1987): 88–93. http://dx.doi.org/10.1139/v87-014.

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A few types of amines XNH2 were investigated for the formation of β-lactams via the cycloaddition of the corresponding Schiff bases with azidoacetyl chloride. Among the β-lactams formed, only the N-p,p′-dimethoxybenzhydryl compounds could be transformed to N-unsubstituted azetidinones by removal of the N-substituent with ceric ammonium nitrate. Conversion of those N-unsubstituted intermediates to 3-acylated monobactams was studied in the 4-styryl series.
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Banik, Bimal K., Anjan Ghatak та Frederick F. Becker. "Indium-mediated facile synthesis of 3-unsubstituted β-lactams". Journal of the Chemical Society, Perkin Transactions 1, № 14 (2000): 2179–81. http://dx.doi.org/10.1039/b002833i.

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Cossío, Fernando P., та Claudio Palomo. "A novel synthetic approach to N-unsubstituted β-lactams". Tetrahedron Letters 26, № 35 (1985): 4235–38. http://dx.doi.org/10.1016/s0040-4039(00)99001-4.

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Alcaide, Benito, Alberto Rodríguez-Vicente та Miguel A. Sierra. "A New Radical Route to C4-Unsubstituted β-Lactams". Tetrahedron Letters 39, № 1-2 (1998): 163–66. http://dx.doi.org/10.1016/s0040-4039(97)10476-2.

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Book chapters on the topic "Unsubstituted β-lactam"

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Bose, Ajay K., Maghar S. Manhas, Arvind Mathur, and Dilip R. Wagle. "α -Unsubstituted β -Lactams as Synthons for Antibiotics." In Recent Progress in the Chemical Synthesis of Antibiotics and Related Microbial Products Vol. 2. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-78250-3_13.

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