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1

Maiti, Amit Bikram, Rabi Hembrom, Rupam Sinha, Satadal Mandal, Mayur M. Nair, and Somnath Patra. "Epidemiological Profile of Foreign Body in Upper Aero-digestive Tract in a Peripheral Tertiary-Care Hospital." Bengal Journal of Otolaryngology and Head Neck Surgery 26, no. 3 (December 7, 2018): 165–70. http://dx.doi.org/10.47210/bjohns.2018.v26i3.202.

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Introduction Foreign body in upper aero-digestive tract leads to many complications including life-threatening ones to the patients. Its management depends upon type of foreign body and site of lodgement. Materials and Methods A descriptive study was conducted from March 2013 to February 2017 to determine the different components of the epidemiological profile of the cases of Foreign body in upper Aero-digestive Tract (UADT) and its management principle. Total 192 patients were selected for this study. These patients underwent different procedures for foreign body removal and post-operative notes were taken for data analysis to note the epidemiological pattern. Results A total of 192 patients were included in the study. Epidemiological data were derived and analyzed comprehensively to present the different profiles. Conclusion Fish bone was found to be the commonest foreign body in upper aero-digestive tract, followed by coin and meat bone. Foreign bodies are commonly removed by Tilley's forceps followed by Hypopharyngoscopy.
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2

Aminianfar, Azadeh, Roohallah Fallah-Moshkani, Asma Salari-Moghaddam, Parvane Saneei, Bagher Larijani, and Ahmad Esmaillzadeh. "Egg Consumption and Risk of Upper Aero-Digestive Tract Cancers: A Systematic Review and Meta-Analysis of Observational Studies." Advances in Nutrition 10, no. 4 (April 30, 2019): 660–72. http://dx.doi.org/10.1093/advances/nmz010.

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ABSTRACT Limited data are available that summarize the relation between egg intake and the risk of upper aero-digestive tract (UADT) cancers. This systematic review and meta-analysis was conducted to investigate the association between egg intake and the risk of UADT cancers. Medline/PubMed, ISI web of knowledge, EMBASE, Scopus, and Google Scholar were searched using relevant keywords. Observational studies conducted on humans investigating the association between egg consumption and the risk of UADT cancers were included. Overall, 38 studies with a total of 164,241 subjects (27, 025 cases) were included. Based on 40 effect sizes from 32 case-control studies, we found a 42% increased risk of UADT cancers among those with the highest egg consumption (ranging from ≥1 meal/d to ≥1 time/mo among studies) compared to those with the lowest intake (ranging from 0–20 g/d to never consumed among studies) (overall OR: 1.42; 95% CI: 1.19, 1.68; P < 0.001). However, this association was only evident in hospital-based case-control (HCC) studies (OR = 1.50; 95% CI: 1.34, 1.68; P < 0.001 for ‘oropharyngeal and laryngeal cancer’ and OR: 1.27; 95% CI: 1.08, 1.50; P = 0.004 for esophageal cancer) and not in population-based case-control (PCC) studies (OR = 1.25; 95% CI: 0.59, 2.67; P = 0.56 for ‘oropharyngeal and laryngeal cancer’ and OR: 1.29; 95% CI: 0.92, 1.81; P = 0.13 for esophageal cancer). In addition, the association was not significant in prospective cohort studies (overall OR: 0.86; 95% CI: 0.71, 1.04; P = 0.11). Considering individual cancers, a positive association was observed between the highest egg consumption, compared with the lowest, and risk of oropharyngeal (OR: 1.88; 95% CI: 1.61, 2.20; P < 0.001), laryngeal (OR: 1.83; 95% CI: 1.45, 2.32; P < 0.001), oral & pharyngeal & laryngeal (OR: 1.37; 95% CI: 1.12, 1.67; P < 0.001), and esophageal cancers (OR: 1.28; 95% CI: 1.10,1.48; P = 0.001). We also found an inverse association between egg intake and the risk of oral cancer (OR: 0.78; 95% CI: 0.62, 0.99; P = 0.04). In conclusion, high egg consumption (ranging from ≥1 meal/d to ≥1 time/mo among studies) was associated with increased risk of UADT cancers only in HCC studies but not in PCC or prospective cohort studies. PROSPERO registration number: CRD42018102619.
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3

Foma, Winga, Bathokedeou Amana, Essobozou Pegbessou, Haréfétéguéna Bissa, Saliou Adam, Warou Dolou, Tchin Darré, Essohanam Boko, and Eyawèlohn Kpemissi. "Upper aero digestive tract cancers: epidemiological and histopathological aspects in Togo." International Journal of Otorhinolaryngology and Head and Neck Surgery 3, no. 1 (December 28, 2016): 11. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20164803.

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<p class="abstract"><strong>Background:</strong> <span lang="EN-GB">The objective of the study was to describe the epidemiological and histopathological aspects of cancer of the upper aero digestive tract (UAT) in a reference service in Togo</span><span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-GB">It was a retrospective study about UAT cancers diagnosed in the ENT and maxillofacial surgery department of Sylvanus Olympio Teaching Hospital of Lomé in Togo from 1st January 2005 to 31 December 2014, or a period of 10 years</span><span lang="EN-IN">. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-GB">The UAT cancers represented 0.3% of consultations and 64.8% of head and neck cancers. The average age of patients was 51.3 years (± 16.5) with extremes of 3 months and 86 years. The sex ratio was 1.77. Chronic smoking was found in 26.4% of patients with 1.6% of women; that of chronic alcoholism among 43.8% of which 7.7% of women and the simultaneous alcoolotabagisme in 20.9% of patients. The UAT cancers were dominated by cancers of the oral cavity (36.2%) with particularly a female predominance (53.2%), followed by the oropharynx (18.5%) and the larynx (18.1%). The squamous cell carcinoma was predominant in UAT cancers (83.5%) followed by non-Hodgkin lymphoma (8.9%) and adenocarcinoma (2.7%)</span><span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-GB">UAT cancers are the largest contingent of head and neck cancers in Togo. They occur most often in men from the fifties but there are a high proportion of women. Histology is dominated by squamous cell carcinoma</span><span lang="EN-IN">.</span></p>
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4

Debta, Priyanka, Santosh Kumar Swain, Mahesh Chandra Sahu, Abdulwahab A. Abuderman, Khalid J. Alzahrani, Hamsa Jameel Banjer, Ahtesham Ahmad Qureshi, et al. "Evaluation of Candidiasis in Upper-Aerodigestive Squamous Cell Carcinoma Patients—A Clinico-Mycological Aspect." International Journal of Environmental Research and Public Health 19, no. 14 (July 12, 2022): 8510. http://dx.doi.org/10.3390/ijerph19148510.

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Candida is a commensal yeast. It can be infective when the host’s defense mechanism is weakened, as in the case of squamous cell carcinoma patients. We aimed to evaluate the prevalence and clinical mycological manifestation of candidiasis in 150 cancer cases comprised of preoperative and post-operative (with or without radiotherapy) upper aerodigestive squamous cell carcinoma. A total of 150 patients suffering from squamous cell carcinoma of the Upper Aero-Digestive Tract (UADT) were divided into preoperative (n = 48), post-operative without radiotherapy (n = 29) and post-operative with radiotherapy (n = 73). Samples were collected using cotton swabs and cultured. Candida species were identified according to color pigmentation on Candida Differential Agar (CDA) plate. The clinico-mycological association of patients was evaluated by the chi-square test, and 98 out of 150 patients showed the presence of various Candida species. The major species isolated was Candida albicans (53%), followed by Candida tropicalis (16%). There was a significant statistical difference between patients who showed mycological associations and patients who did not have any such association (p = 0.0008). The prevalence of oral candidiasis was found to be 65.33% among total cases of upper aero-digestive squamous cell carcinoma. Chronic erythematous cases of candidiasis were mainly seen in preoperative squamous cell carcinoma cases, whereas the acute erythematous type of candidiasis was mainly seen in post-operative cases who received radiotherapy. The clinicomycological assessment can help to correlate the signs and symptoms with the presence of candidiasis in upper aerodigestive squamous cell carcinoma patients. Meticulous testing and examination can help in the early detection of candidiasis. Future studies are needed to develop advance scientific preventive strategies for high-risk cases.
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5

Oh, Kyung Kyoon, Kyung Man Chang, Guk Haeng Lee, Yoon Sang Shim, and Moo Jin Choo. "Papilloma of the Upper Aero-digestive Tract." Journal of Clinical Otolaryngology Head and Neck Surgery 4, no. 2 (November 1993): 352–58. http://dx.doi.org/10.35420/jcohns.1993.4.2.352.

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6

Violaris, N. S., and P. C. Windle-Taylor. "Idiopathic fibrosis of the upper aero-digestive tract." Journal of Laryngology & Otology 103, no. 3 (March 1989): 333–34. http://dx.doi.org/10.1017/s0022215100108862.

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AbstractIdiopathic fibrosis of different areas of the body such as retroperitoneal fibrosis, mediastinal fibrosis, sclerosing cholangitis, Reidel's thyroiditis and pseudo-tumour of the orbit are well recognised entities that manifest individually or in combination. A case of idiopathic fibrosis of the upper aerodigestive tract is presented, which caused dense fibrosis of the floor of mouth, tongue, pharynx and larynx leading to aphonia and severe dysphagia. A permanent tracheostomy was performed and regular bouginage is necessary. This is the first such case reported in the literature.
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7

Paderno, Alberto, Alessandro Gronchi, and Cesare Piazza. "Synovial sarcomas of the upper aero-digestive tract." Current Opinion in Otolaryngology & Head and Neck Surgery 26, no. 2 (April 2018): 94–101. http://dx.doi.org/10.1097/moo.0000000000000440.

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8

McCombe, Andrew, Valerie J. Lund, and David J. Howard. "Multiple synchronous carcinoma of the aero-digestive tract." Journal of Laryngology & Otology 103, no. 8 (August 1989): 794–95. http://dx.doi.org/10.1017/s0022215100110114.

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AbstractMultiple carcinoma of the upper aerodigestive tract is an increasingly recognized problem, and a concept of ‘field cancerization’ has been proposed to explain this phenomena. The initial assessment of a patient with an isolated aerodigestive carcinoma must be extensive so as not to miss any synchronous lesions, and may include radiography and endoscopy. Treatment cannot be standardised but must be tailored to suit individual problems and because of the high incidence of metachronous tumours, follow-up must be both thorough and ‘lifelong’.A case of three primary synchronous squamous carcinomas of the upper aerodigestive tract is presented. The relevant literature is reviewed.
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9

Gupta, Rahul, and Ashok Gupta. "Near Complete Laryngopharyngeal Obstruction due to Vegetable Foreign Body in an Infant." Bengal Journal of Otolaryngology and Head Neck Surgery 26, no. 1 (April 28, 2018): 64–68. http://dx.doi.org/10.47210/bjohns.2018.v26i1.159.

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Introduction Impaction of foreign bodies and obstruction in the upper aero-digestive tract is a medical emergency. Case Report A 5-month-old male infant presented with impacted large vegetable foreign body lying in the hypopharynx of an infant causing almost complete laryngeal obstruction. Cardiopulmonary resuscitation was initiated and back blows were given between the blades of the scapula to assist in its removal. Only available curved artery forceps was gently passed beyond the foreign body; blades of the forceps were opened to engage it and foreign body was swept and rolled out. Patient was revived after intensive resuscitation. Conclusion Suspect foreign body in the upper aero-digestive tract in any child presenting with severe respiratory distress or apneic spells or choking. Foreign body may be removed with only available curved artery forceps by gently passing beyond it, followed by opening and engaging blades of the forceps to sweep and roll it out of the upper aero-digestive tract.
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10

Pandey, Manoj, Elizabeth K. Abraham, Aleyamma Mathew, and Iqbal M. Ahamed. "Primary malignant melanoma of the upper aero-digestive tract." International Journal of Oral and Maxillofacial Surgery 28, no. 1 (February 1999): 45–49. http://dx.doi.org/10.1034/j.1399-0020.1999.280111.x.

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11

Pandey, Manoj, Elizabeth K. Abraham, Aleyamma Mathew, and Iqbal M. Ahamed. "Primary malignant melanoma of the upper aero-digestive tract." International Journal of Oral and Maxillofacial Surgery 28, no. 1 (February 1999): 45–49. http://dx.doi.org/10.1016/s0901-5027(99)80676-6.

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12

Gupta, Bhawna, Ratilal Lalloo, and Newell W. Johnson. "Life course models for upper aero-digestive tract cancer." International Dental Journal 65, no. 3 (June 2015): 111–19. http://dx.doi.org/10.1111/idj.12167.

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13

Karnwal, A., E. C. Ho, A. Hall, and N. Molony. "Lateral soft tissue neck X-rays: are they useful in management of upper aero-digestive tract foreign bodies?" Journal of Laryngology & Otology 122, no. 8 (August 15, 2007): 845–47. http://dx.doi.org/10.1017/s0022215107000497.

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AbstractObjectives:To assess the value of lateral soft tissue neck X-rays in patients presenting with upper aero-digestive tract foreign bodies.Design:Retrospective study.Inclusion criteria:(1) Patients referred to the ENT team, via either the accident and emergency department or their general practitioner; (2) a history of a non-aspirated, upper airway, aero-digestive tract foreign body; and (3) a lateral soft tissue neck X-ray taken on admission.Results:A total of 62 patients met the inclusion criteria. Twenty-four patients (38.7 per cent) had positive findings on lateral soft tissue neck X-ray. ‘Soft’ signs, such as widened pre-vertebral shadow and loss of lordosis, were seen in all 24 patients, and foreign bodies were visualised in six patients. Overall, lateral soft tissue neck X-rays were helpful in the management of 32 patients (51.6 per cent). Rather worryingly, doctors in the accident and emergency and ENT departments missed 79.2 and 66.6 per cent of the positive findings, respectively.Conclusions:A lateral soft tissue neck X-ray is a helpful tool in the management of patients presenting with upper aero-digestive tract foreign bodies. Junior doctors need better radiology training.
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14

Gupta, Pallavi, and A. Jain. "Foreign bodies in upper aero-digestive tract: a clinical study." International Journal of Research in Medical Sciences 2, no. 3 (2014): 886. http://dx.doi.org/10.5455/2320-6012.ijrms20140823.

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15

Raza, Maqbool, Atif Rafique, Shahid Farooq Khattak, Farhan Majeed, Khalid Azam, and Ghulam Farid. "PATTERN OF FOREIGN BODIES AERO DIGESTIVETRACT – A SINGLE CENTRE STUDY." PAFMJ 71, Suppl-1 (January 27, 2021): S57–61. http://dx.doi.org/10.51253/pafmj.v71isuppl-1.5270.

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Objective: To find out the pattern of foreign bodies inhaled or ingested in a series of patients. Study Design: Case series. Place and Duration of Study: Ear, Nose and Throat (ENT) department, Pak Emirates Military Hospital (PEMH)Rawalpindi, Jan 2016 to Dec 2016. Methodology: A total of 46 cases of foreign body upper aero digestive tract who presented in the ENTDepartment, PEMH Rawalpindi in 2016 were included in this study. Twenty eight cases were of foreign bodyesophagus and 18 were of foreign body airway. The age, gender, duration of foreign body lodgment, types offoreign body’s physical signs and symptoms were recorded. Relevant radiographic studies were performed. Results: Out of 46 patients of foreign body aero digestive tract 33 were males and 13 were females. The overallfrequency of foreign bodies’ upper aero digestive tract was 46 (0.14%) with 28 (0.08%) being foreign bodiesesophagus and 18 (0.06%) foreign bodies airway. In 50% cases of bronchial foreign bodies were in age group 0-3 years. The most frequent foreign body in the esophagus was coin in 13(46.4%) followed by chicken bone 5 (17.8%) and fish bone 3 (10.7%). Peanuts, peas, and beans were predominant component of the airway foreign bodies constituting 6 (33.3%), 3 (16.6%) and 3 (16.6%) respective of the total. Most frequent sites of impaction of the foreign body were cervical esophagus 16 (34%), right main bronchus 11 (23.9%) and left main bronchus 3 (6.5%). Conclusion: Foreign body aero digestive tract is an uncommon but potentially life..........
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Lancer, J. M., and A. A. Moir. "The flexible fibreoptic rhinolaryngoscope." Journal of Laryngology & Otology 99, no. 8 (August 1985): 767–70. http://dx.doi.org/10.1017/s0022215100097632.

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AbstractAn accurate, reliable, inexpensive and safe method for the examiniation of the upper aero-digestive tract is described. Its efficacy is evaluated retrospectively on 250 patients over an 18-month period.
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Casale, Manuele, Antonio Moffa, Lorenzo Sabatino, Annalisa Pace, Giuseppe Oliveto, Massimiliano Vitali, Peter Baptista, and Fabrizio Salvinelli. "Hyaluronic Acid: Perspectives in Upper Aero-Digestive Tract. A Systematic Review." PLOS ONE 10, no. 6 (June 29, 2015): e0130637. http://dx.doi.org/10.1371/journal.pone.0130637.

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Panis, Xavier, Liliane Demange, Dominique Froissart, and Tan Dat Nguyen. "Squamous cell carcinoma of the upper aero-digestive tract in women." Radiotherapy and Oncology 13, no. 3 (November 1988): 175–79. http://dx.doi.org/10.1016/0167-8140(88)90053-9.

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Lancer, J. M., and A. S. Jones. "Flexible fibreoptic rhinolaryngoscopy." Journal of Laryngology & Otology 99, no. 8 (August 1985): 771–73. http://dx.doi.org/10.1017/s0022215100097644.

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AbstractFlexible fibreoptic rhinolaryngoscopy has been shown to be an accurate, reliable, inexpensive and safe method of examining the upper aero-digestive tract (Lancer and Moir, 1985).The result of 338 consecutive examinations are reported.
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20

Mohammed, H., L. Masterson, and R. Nassif. "Out-patient flexible carbon dioxide laser surgery for benign laryngopharyngeal pathologies via transnasal flexible laryngo-oesophagoscopy." Journal of Laryngology & Otology 131, no. 7 (April 20, 2017): 650–54. http://dx.doi.org/10.1017/s0022215117000792.

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AbstractObjective:To assess the feasibility and outcomes of flexible carbon dioxide laser surgery in a clinic-based setting.Methods:A prospective study was conducted in a tertiary centre. Clinical indications, clinical outcomes and patient satisfaction were assessed in patients treated with flexible carbon dioxide laser surgery via transnasal endoscopy and followed up over a period of up to nine months. Patients who were not fit for general anaesthesia or those with lesions that cannot be accessed by micro-laryngoscopy were included.Results:A total of 13 patients (14 procedures) were included. Clinical indications for surgery were small-to-medium sized benign pathologies in the upper aero-digestive tract. Patient satisfaction was assessed using a validated questionnaire.Conclusion:Early data suggest that flexible carbon dioxide laser is a versatile and feasible instrument with potential applications for a range of benign pathologies in the upper aero-digestive tract.
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Bosetti, Cristina, Claudio Pelucchi, and Carlo La Vecchia. "Diet and cancer in Mediterranean countries: carbohydrates and fats." Public Health Nutrition 12, no. 9A (September 2009): 1595–600. http://dx.doi.org/10.1017/s1368980009990425.

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AbstractObjectiveSeveral aspects of the diet characteristic of the Mediterranean countries are considered favourable not only on cardiovascular disease, but also on cancer risk. We considered some aspects of the Mediterranean diet (including, in particular, the consumption of olive oil and carbohydrates) on cancer risk.Design, Setting and SubjectsData were derived from a series of case-control studies, conducted in Italy since the early 1990s, on over 10 000 cases of thirteen cancer sites and over 17 000 controls.ResultsOlive oil, and other mono- and unsaturated fats, appear to be favourable indicators of breast, ovarian, colorectal, but mostly of upper aero-digestive tract cancers. Whole grain foods are also related to reduced risk of upper aero-digestive tract and various other cancers. In contrast, refined grain intake and, consequently, glycaemic index and glycaemic load were associated to increased risk for several cancer sites. Fish, and hence a diet rich in n-3 polyunsaturated fatty acids, tended to be another favourable diet indicator, while frequent red meat intake was directly related to some common neoplasms. An a priori defined Mediterranean diet score was inversely related to upper digestive and respiratory tract cancers.ConclusionsThese data provide additional evidence that major characteristics of the Mediterranean diet favourably affect cancer risk.
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M., PRABHAKARAN. "Upper Aero Digestive Tract Cancer: A Detailed Exploration Using Computer Vision Techniques." Journal of Research on the Lepidoptera 51, no. 2 (June 25, 2020): 648–65. http://dx.doi.org/10.36872/lepi/v51i2/301124.

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Waridel, F., A. Estreicher, L. Bron, J.-M. Flaman, C. Fontolliet, P. Monnier, T. Frebourg, and R. Iggo. "Field cancerisation and polyclonal p53 mutation in the upper aero- digestive tract." Oncogene 14, no. 2 (January 1997): 163–69. http://dx.doi.org/10.1038/sj.onc.1200812.

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Anantharaman, Devasena, Tarik Gheit, Tim Waterboer, Behnoush Abedi-Ardekani, Christine Carreira, Sandrine McKay-Chopin, Valerie Gaborieau, et al. "Human Papillomavirus Infections and Upper Aero-Digestive Tract Cancers: The ARCAGE Study." JNCI: Journal of the National Cancer Institute 105, no. 8 (March 16, 2013): 536–45. http://dx.doi.org/10.1093/jnci/djt053.

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Dal Maso, Luigino, Carlo La Vecchia, Jerry Polesel, Renato Talamini, Fabio Levi, Ettore Conti, Paola Zambon, Eva Negri, and Silvia Franceschi. "Alcohol drinking outside meals and cancers of the upper aero-digestive tract." International Journal of Cancer 102, no. 4 (October 24, 2002): 435–37. http://dx.doi.org/10.1002/ijc.10723.

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Panagamuwa, C., S. Gane, and D. Hajioff. "A novel method for replacement of a blocked fine bore nasogastric tube." Journal of Laryngology & Otology 117, no. 11 (November 2003): 883–84. http://dx.doi.org/10.1258/002221503322542908.

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Nasogastric intubation is often difficult in patients with upper aero-digestive tract tumours. We present a new method for replacing obstructed fine-bore nasogastric tubes. This method eliminates the need for specialized equipment and skills, minimizes the risk of tracheal intubation and oesophageal trauma, and is better tolerated by patients.
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Sah, Bajrang Prasad, Shyam Thapa Chhetri, Shankar Prasad Sah, Deepak Paudel, and Deependra Prasad Sarraf. "A Prospective Study of Foreign Bodies in Aero-Digestive Tract at a Tertiary Care Center in Eastern Nepal." Medical Journal of Eastern Nepal 1, no. 02 (December 31, 2022): 44–48. http://dx.doi.org/10.3126/mjen.v1i02.51163.

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Background Aero-digestive tract foreign body (FB) is a common emergency dealt by the otolaryngologists. Airways FB have been a major cause of morbidity and mortality. Management of FB depends on the site of impaction and types of it. The study aimed to find out the incidence, types and complications of FB encountered in aerodigestive tract. Methods A hospital-based prospective study was conducted among the patients with aero digestive FB presented and managed at the department of ENT and HNS from August 2015 to July 2017. A self-designed proforma was used to collect the relevant data. A descriptive analysis was made of the frequency distribution of qualitative variables. The findings were presented as tables and graphs. Results A total of 276 patients were treated for FB in aero-digestive tract and 158 (57.25%) patients were male. 90 (32.6%) cases of FB occurred in age group of 1-10 years. Ninety six cases of foreign body (34.78%) were chicken bone followed by other bone (20.65%) and coin (18.12%). All cases of coin were seen in children <13 years old and disc Battery in children <10 years old. Out of 276 cases of foreign bodies, 254 (92.03%) were in upper digestive tract and 22 (7.97%) in airways. About 140 (50.72%) were in cricopharynx, 103 (37.32%) in esophagus and 11 (3.99%) in other sites in intestine.Complications were seen in 10 (3.62%) cases and retropharyngeal abscess was the most common (60%). Conclusion Cricopharynx was the most common site of FB lodgment in the digestive tract. Right main bronchus was the commonest site of lodgment of inhaled FB. Seeds, nuts, whistles, small toys were commonly seen obstructing the airway in children. They need to be trained not to keep these things in the mouth.
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Samor, Vivek, Deepchand Sarowa, Pooja D. Nayak, Vaibhav Saini, Gagandeep Kaur, and Uma Rathi. "Rare foreign bodies of upper aerodigestive tract: a study of 30 cases." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 7 (June 25, 2020): 1307. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20202602.

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<p class="abstract"><strong>Background:</strong> Aero-digestive foreign bodies are prevalent in our part of the country. Apart from the usual foreign body we encountered some unique foreign bodies, the diagnosis and management of which, is difficult due to varied and overlapping clinical presentation. Rare foreign bodies in the aero-digestive tract pose challenges in diagnosis and treatment.</p><p class="abstract"><strong>Methods:</strong> This was a retrospective observational study on thirty patients with aerodigestive foreign bodies who visited our hospital from July 2015 to October 2017. </p><p class="abstract"><strong>Results:</strong> Maximum number of cases was seen in age group of 0-5 years. The male to female ratio was 2:1. Among various types of foreign bodies, majority were metallic (43.3%). The most common site was cricopharynx (53.3%) followed by bronchus (26.6%) and esophageal (16.6%). The most common procedure done was hypopharyngoscopy (53.3%).</p><p class="abstract"><strong>Conclusions:</strong> Aerodigestive tract foreign bodies are one of the emergencies that have considerable mortality and morbidity. High degree of skill and suspicion are required by surgeon for the management of foreign body.</p>
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Izzo, J. G., W. N. Hittelman, D. D. Liu, J. J. Lee, X. Wu, W. K. Hong, and V. A. Papadimitrakopoulou. "Cyclin D1 polymorphism, biochemoprevention and risk of upper aero-digestive tract cancer development." Journal of Clinical Oncology 22, no. 14_suppl (July 15, 2004): 1006. http://dx.doi.org/10.1200/jco.2004.22.14_suppl.1006.

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Izzo, J. G., W. N. Hittelman, D. D. Liu, J. J. Lee, X. Wu, W. K. Hong, and V. A. Papadimitrakopoulou. "Cyclin D1 polymorphism, biochemoprevention and risk of upper aero-digestive tract cancer development." Journal of Clinical Oncology 22, no. 14_suppl (July 15, 2004): 1006. http://dx.doi.org/10.1200/jco.2004.22.90140.1006.

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31

Skinner, D. W., and P. J. Bradley. "Psychogenic stridor." Journal of Laryngology & Otology 103, no. 4 (April 1989): 383–85. http://dx.doi.org/10.1017/s0022215100109028.

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AbstractObstruction of the laryngeal airway is a life threatening problem due normally to obstructive pathology within the upper aero-digestive tract. We describe four cases of laryngeal stridor (two adults and two children) of psychogenic origin, one of which required a tracheostomy. The literature is reviewed and the subsequent pattern of this disease documented on the basis of 28 patients previously described.
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32

Sanders, J. G., K. G. Smith, M. B. Jameson, C. de Groot, and J. White. "Persistent neck disease after chemoradiation for head and neck squamous cell carcinoma." Journal of Laryngology & Otology 126, no. 11 (September 19, 2012): 1121–26. http://dx.doi.org/10.1017/s0022215112002009.

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AbstractObjective:This study aimed to identify the incidence of residual viable neck disease in patients with mucosal squamous cell carcinoma of the upper aero-digestive tract, following primary chemoradiation at a tertiary centre.Study design:Retrospective review.Methods:Retrospective chart review of patients treated with primary chemoradiation for squamous cell carcinoma of the aero-digestive tract between August 2001 and August 2008. Neck status pre- and post-treatment was the primary focus.Results:Forty-two patients with node-positive disease prior to chemoradiation were included. Thirty-seven (88.1 per cent) achieved complete response to treatment: no patient in this group underwent neck dissection, five died due to recurrence at the primary site or distant metastasis, and none suffered neck recurrence. Five (11.9 per cent) patients achieved partial response to chemoradiation and underwent neck dissection; viable tumour was found in one patient.Conclusion:Our data support conservative management of the neck in patients with complete response to chemoradiation, and consolidation neck dissection in patients with partial response.
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33

Al-Mobeerik, Aziza. "Oral and Upper Aero-Digestive Tract Malignancy: A Review of a Five-Year Experience." Annals of Saudi Medicine 18, no. 3 (May 1998): 257–59. http://dx.doi.org/10.5144/0256-4947.1998.257.

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34

Mathialagan, Prabhakaran, and Malathy Chidambaranathan. "Computer vision techniques for Upper Aero-Digestive Tract tumor grading classification – Addressing pathological challenges." Pattern Recognition Letters 144 (April 2021): 42–53. http://dx.doi.org/10.1016/j.patrec.2021.01.002.

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35

Franco, Eduardo L. "Multiple cancers of the upper aero-digestive tract: the challenge of risk factor identification." Cancer Letters 60, no. 1 (October 1991): 1–8. http://dx.doi.org/10.1016/0304-3835(91)90042-g.

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36

Vellamparambil, Sreeja Raj, Arjun Gopinath Menon, and Ariyamparambil Rajagopalan Vinayakumar. "Endoscopic removal of foreign bodies from the upper aerodigestive tract: a retrospective study from a tertiary care hospital." International Journal of Otorhinolaryngology and Head and Neck Surgery 5, no. 4 (June 27, 2019): 960. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20192712.

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<p class="abstract"><strong>Background:</strong> Foreign bodies (FB) in the upper aero-digestive tract pose major challenges to the otorhinolaryngologist in both diagnosis and management. Aspirated and ingested foreign bodies are often emergencies, leading to inadequate study, poor preparation and improper attempts at removal. A retrospective analysis was done on cases which were managed for the upper aero-digestive tract FBs in a tertiary care hospital in South India and the result is presented in this article.</p><p class="abstract"><strong>Methods:</strong> Retrospective study was done on 100 patients diagnosed as cases of foreign body in upper aerodigestive tract on the basis of detailed history, clinical examination and radiological investigation. They underwent per oral endoscopy under general anaesthesia for retrieval of foreign body. </p><p class="abstract"><strong>Results:</strong> Age group more prone for foreign body ingestion or aspiration was &lt;10 years and &gt;50 years. Most common site of impaction in oesophagus is cricopharynx and in airway is right bronchus. Most common type of FB is chicken bone. Most common symptom in FB ingestion is FB sensation and in case of FB aspiration it is cough. Most (82%) of the FBs were radio opaque.</p><p class="abstract"><strong>Conclusions:</strong> Accurate history and clinical examination were the keystones in diagnosis and prevention of complications of FB lodgement in aerodigestive tract. Negative history and or normal imaging do not rule out a foreign body.</p>
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37

Syrjänen, Stina, and Kari Syrjänen. "HPV-Associated Benign Squamous Cell Papillomas in the Upper Aero-Digestive Tract and Their Malignant Potential." Viruses 13, no. 8 (August 17, 2021): 1624. http://dx.doi.org/10.3390/v13081624.

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Squamous cell papilloma (SCP) in the upper aero-digestive tract is a rare disease entity with bimodal age presentation both at childhood and in adults. It originates from stratified squamous and/or respiratory epithelium. Traditionally, SCPs have been linked to chemical or mechanical irritation but, since the 1980s, they have also been associated with human papillomavirus (HPV) infection. Approximately 30% of the head and neck SCPs are associated with HPV infection, with this association being highest for laryngeal papillomas (76–94%), followed by oral (27–48%), sinonasal (25–40%), and oropharyngeal papillomas (6–7%). There is, however, a wide variation in HPV prevalence, the highest being in esophageal SCPs (11–57%). HPV6 and HPV11 are the two main HPV genotypes present, but these are also high-risk HPVs as they are infrequently detected. Some 20% of the oral and oropharyngeal papillomas also contain cutaneous HPV genotypes. Despite their benign morphology, some SCPs tend to recur and even undergo malignant transformation. The highest malignant potential is associated with sinonasal inverted papillomas (7–11%). This review discusses the evidence regarding HPV etiology of benign SCPs in the upper aero-digestive tract and their HPV-related malignant transformation. In addition, studies on HPV exposure at an early age are discussed, as are the animal models shedding light on HPV transmission, viral latency, and its reactivation.
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38

Koshiaris, C., P. Aveyard, J. Oke, R. Ryan, L. Szatkowski, R. Stevens, and A. Farley. "Smoking cessation and survival in lung, upper aero-digestive tract and bladder cancer: cohort study." British Journal of Cancer 117, no. 8 (September 12, 2017): 1224–32. http://dx.doi.org/10.1038/bjc.2017.179.

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39

Wolfensberger, Markus. "Using Cox's Proportional Hazards Model for Prognostication in Carcinoma of the Upper Aero-Digestive Tract." Acta Oto-Laryngologica 112, no. 2 (January 1992): 376–82. http://dx.doi.org/10.1080/00016489.1992.11665437.

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40

Mulherkar, Rita, Anuradha P. Goud, Archana S. Wagle, K. N. Naresh, Manoj B. Mahimkar, Sufi M. Thomas, S. A. Pradhan, and M. G. Deo. "Establishment of a human squamous cell carcinoma cell line of the upper aero-digestive tract." Cancer Letters 118, no. 1 (September 1997): 115–21. http://dx.doi.org/10.1016/s0304-3835(97)00241-3.

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41

Rydell, E. L., K. L. Axelsson, J. Olofsson, and J. E. S. Wikberg. "Guanylate Cyclase Activity in Normal and Neoplastic Squamous Epithelia from the Upper Aero-Digestive Tract." ORL 48, no. 5 (1986): 265–69. http://dx.doi.org/10.1159/000275880.

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42

Calabrese, V., M. Cifola, R. Pareschi, A. Parma, and A. Sonzogni. "Primary malignant melanoma of the oral cavity." Journal of Laryngology & Otology 103, no. 9 (September 1989): 887–89. http://dx.doi.org/10.1017/s0022215100110412.

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AbstractPrimary mucosal melanomas of the upper aero-digestive tract are uncommon and represent only 1.7 to 3 per cent of all primary melanomas. The most frequent localization are the nasal fossae, the paranasal sinuses and the oral cavity where melanomas most often arise from the palate and alveolar ridge, buccal mucosa, lips, tongue and floor of mouth.The authors describe a case of malignant melanoma of the uvula, review the literature and discuss the aetiology, pathology and diagnostic and therapeutic problems.
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43

Tandon, D. A., S. Bahadur, H. C. Laldina, and K. R. Sundaram. "Role of prophylactic antibiotics in surgery for advanced head and neck cancer." Journal of Laryngology & Otology 106, no. 7 (July 1992): 621–24. http://dx.doi.org/10.1017/s0022215100120353.

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AbstractFour regimens of prophylactic antibiotics were utilized in 122 consecutive patients of stages III and IV carcinoma of the upper aero-digestive tract undergoing major resections in a randomized single-blind study. Ampicillin, gentamicin, cephalexin and metronidazole were used in different combinations for periods of 5 or 10 days. A cephalexin-metronidazole protocol for 10 days was associated with lowest post-operative infection rate. Oral-oropharyngeal resection and use of pectoralis major myocutaneous flap were the most important factors contributing to infection.
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44

Stimac, Gregory Paul, and Asefa Jejaw Mekonnen. "Obstructive sleep apnoea in a patient with chronic lymphocytic leukaemia." BMJ Case Reports 12, no. 7 (July 2019): e228763. http://dx.doi.org/10.1136/bcr-2018-228763.

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A 69-year-old Caucasian woman presented with chronic lymphocytic leukaemia (CLL; stage 1-Rai System), significant oropharyngeal lymphoid enlargement, snoring and fatigue. Overnight polysomnography revealed moderately severe obstructive sleep apnoea (OSA), which was managed successfully with oral appliance therapy with resolution of snoring and daytime fatigue. Structural abnormalities of the upper airways are known to cause OSA. Airway narrowing can result from bony structural abnormalities, nasopharyngeal growth, soft tissue redundancy, macroglossia, malignant and benign growth of the upper aero-digestive tract, and adenotonsilar enlargement. Clinicians should be encouraged to consider a diagnosis of OSA in patients with CLL when they present with symptoms of worsening fatigue.
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45

Saravanan, K., S. T. Baer, A. Meredith, A. Dyson, and Jan von der Werth. "Benign mucous membrane pemphigoid of the upper aero-digestive tract: rare paraneoplastic syndrome presentation in renal cell carcinoma." Journal of Laryngology & Otology 120, no. 3 (January 26, 2006): 237–39. http://dx.doi.org/10.1017/s0022215106000193.

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Benign mucous membrane pemphigoid is a rare autoimmune disorder affecting the upper aero-digestive tract and conjunctivae. This is a case presentation of benign mucous membrane pemphigoid affecting the oral mucosa, pharynx, oesophagus and larynx, leading to cicatricial lesions in the pharynx and larynx, causing dysphagia, hoarseness and stridor. The alternative forms of management for laryngeal scarring due to this disease are explained. The patient was later diagnosed with advanced renal cell carcinoma, raising the possibility of cicatricial pemphigoid manifesting as a paraneoplastic syndrome of underlying renal cell carcinoma.
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46

Bhagat, Vasudha, Peeyush Saini, Hemali Tailor, Reena Dudhat, Amita Patel, and Jigna Modi. "Histopathological spectrum of tumours of upper aero digestive tract in Surat - A study of 156 cases." International Journal of Medical Science and Public Health 2, no. 4 (2013): 971. http://dx.doi.org/10.5455/ijmsph.2013.090720133.

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47

Gupta, Bhawna, and Newell W. Johnson. "Emerging and Established Global Life-Style Risk Factors for Cancer of the Upper Aero-Digestive Tract." Asian Pacific Journal of Cancer Prevention 15, no. 15 (August 15, 2014): 5983–91. http://dx.doi.org/10.7314/apjcp.2014.15.15.5983.

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48

Sharma, Jagannath Dev, Manoj Kalita, Debanjana Barman, Arpita Sharma, Ranjan Lahon, Jamil Ahmed Barbhuiya, Barsha Deka, and Amal Chandra Kataki. "Patterns of Upper Aero-digestive Tract Cancers in Kamrup Urban District of Assam: A Retrospective Study." Asian Pacific Journal of Cancer Prevention 15, no. 17 (September 15, 2014): 7267–70. http://dx.doi.org/10.7314/apjcp.2014.15.17.7267.

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49

Gregori, D., and F. Foltran. "Foreign body injuries in the upper-aero-digestive tract in children: the Susy Safe project results." Injury Prevention 16, Supplement 1 (September 1, 2010): A216. http://dx.doi.org/10.1136/ip.2010.029215.771.

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50

Jayasekara, Harindra, Robert J. MacInnis, Allison M. Hodge, John L. Hopper, Graham G. Giles, Robin Room, and Dallas R. English. "Lifetime alcohol consumption and upper aero-digestive tract cancer risk in the Melbourne Collaborative Cohort Study." Cancer Causes & Control 26, no. 2 (November 18, 2014): 297–301. http://dx.doi.org/10.1007/s10552-014-0495-y.

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