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Journal articles on the topic 'UPSC'

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1

Wu, Pengju, Mengqi Zhang, Yanlu Kou, et al. "Identification of novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A." mLife 4, no. 1 (2025): 17–28. https://doi.org/10.1002/mlf2.12163.

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AbstractIn Sulfolobales cells, transcription of the Ups (UV‐inducible pili of Sulfolobus) and Ced (Crenarchaeal system for exchange of DNA) genes is highly induced by DNA damage, and the two systems play key roles in pili‐mediated cell aggregation and chromosomal DNA import, respectively. Ups is composed of UpsA, UpsB, UpsE, and UpsF, while Ced is composed of CedA, CedA1, CedA2, and CedB. So far, how DNA is transported by these systems is far from clear. Here, we report three novel components of the Ced and Ups systems in Saccharolobus islandicus REY15A, CedD (SiRe_1715) and CedE (SiRe_2100),
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2

Grimm, Alexander. "Der „Ultrasound pattern sum score“ – ein möglicher Algorithmus in der Anwendung des Nervenultraschalls bei Polyneuropathien." Klinische Neurophysiologie 48, no. 02 (2017): 93–101. http://dx.doi.org/10.1055/s-0043-104917.

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ZusammenfassungDie Wertigkeit des Nervenultraschalls bei Polyneuropathie wird aktuell intensiv diskutiert und untersucht. Ziel der UPSS-Studie war daher die Erarbeitung eines standardisierten und operationalisierten Untersuchungsablaufs für die systematische Erfassung sonografischer Nervenbefunde. Methodik 61 Patienten mit akuter oder subakuter Polyneuropathie wurden systematisch sonografisch untersucht. Auf Basis der unterschiedlichen Beteiligung verschiedener Nerven bei individuellen PNP-Syndromen konnten Kompartimente eingeteilt (UPSA=sensomotorische Nerven, UPSB=Wurzeln und N. vagus, UPSC=
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3

Greggi, Stefano, Giorgia Mangili, Cono Scaffa, et al. "Uterine Papillary Serous, Clear Cell, and Poorly Differentiated Endometrioid Carcinomas: A Comparative Study." International Journal of Gynecologic Cancer 21, no. 4 (2011): 661–67. http://dx.doi.org/10.1097/igc.0b013e3182150c89.

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Introduction:Uterine papillary serous and clear cell carcinomas (UPSCs/CCs) show a different spreading from that of poorly differentiated endometrioid carcinomas (PDECs) and are usually thought to be prognostically more aggressive than PDECs. On the contrary, it has been recently claimed that UPSC/CC and PDEC have a similar prognosis. In this retrospective study on 2 institutional databases, the surgical-pathological data and survival have been compared in patients with UPSC/CC and PDEC.Methods:A total of 139 surgically staged consecutive patients, 63 with UPSC/CC (37 UPSC; 26 CC) and 76 with
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4

Faratian, D., A. Stillie, R. M. C. Busby-Earle, V. J. Cowie, and H. Monaghan. "A review of the pathology and management of uterine papillary serous carcinoma and correlation with outcome." International Journal of Gynecologic Cancer 16, no. 3 (2006): 972–78. http://dx.doi.org/10.1136/ijgc-00009577-200605000-00003.

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Uterine papillary serous carcinoma (UPSC) accounts for 10% of endometrial carcinomas but a higher proportion of deaths due to its aggressive nature and poor response to chemotherapy and radiotherapy. In order to add to the knowledge of UPSC in the literature and to review our local practices, we examined the pathology, medical records, and management of all cases of UPSC (67 patients) treated in South East Scotland over a 10-year period and also evaluated the prognostic significance of the percentage of UPSC in endometrial pipelle and hysterectomy specimens. Although only 63% of initial diagno
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5

Stine, Jessica E., Stuart Pierce, Paola A. Gehrig, et al. "Recurrence rates in patients with uterine papillary serous cancer with and without breast cancer." Journal of Clinical Oncology 31, no. 15_suppl (2013): e16529-e16529. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e16529.

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e16529 Background: Women with uterine papillary serous carcinoma (UPSC) are at increased risk for breast cancer and the converse is true. A genetic association between breast cancer and UPSC was recently described and counseling women faced with more than one cancer diagnosis can be difficult. Our objective was to evaluate recurrence rates of women with UPSC to those with UPSC and a personal history of breast cancer (UPSCBR). Methods: Data was collected for UPSCBR patients at two academic institutions between 7/1990 and 7/2012. Patient demographics, pathology, disease stage, and treatments wer
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6

Lee, Kevin J., Tanvi Joshi, Sagar Chokshi, Mackenzie Cummings, Jennifer Scalici, and Nathaniel Jones. "Abstract 500: A molecular comparison reveals distinct transcriptomic differences between uterine carcinosarcoma and papillary serous carcinoma distinguishable by DNA damage." Cancer Research 85, no. 8_Supplement_1 (2025): 500. https://doi.org/10.1158/1538-7445.am2025-500.

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Abstract Background: Uterine papillary serous carcinoma (UPSC) and uterine carcinosarcoma (UCS) are rare subtypes of endometrial cancer (EMCA) with poor prognosis. Both are high risk histotypes, though their distinct molecular and genomic profiles are undefined. Recent clinical trials such as RUBY, Keynote 775, DUO-E and NRG-GY018 have shown survival benefit in subsets of EMCA with mismatch repair deficiency (MMRd), however, small numbers of patients with UPSC and UCS were included. The role of MMRd or DNA damage & response (DDR) mechanisms in general are under-explored in these EMCA subty
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7

Kwon, J. S., J. Abrams, A. Sugimoto, and M. S. Carey. "Is adjuvant therapy necessary for Stage IA and IB uterine papillary serous carcinoma and clear cell carcinoma after surgical staging?" International Journal of Gynecologic Cancer 18, no. 4 (2008): 820–24. http://dx.doi.org/10.1136/ijgc-00009577-200807000-00033.

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Adjuvant therapy of early-stage uterine papillary serous carcinoma (UPSC) and clear cell carcinoma (CCC) is controversial. We conducted a prospective cohort study to evaluate outcomes of patients with early-stage UPSC or CCC who were followed without adjuvant therapy after complete surgical staging. From 2000 to 2006, we evaluated all consecutive patients with stage IA/IB UPSC or CCC who had surgical staging by a gynecological oncologist at the London Health Sciences Centre, Canada. Follow-up consisted of history and physical examination every 3 months for 2 years, then every 6 months for the
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8

de Souza, B. "Biologic behavior for patterns of recurrence and survival in ovarian versus uterine papillary serous carcinoma." Journal of Clinical Oncology 24, no. 18_suppl (2006): 15056. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.15056.

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15056 Background: Papillary serous carcinoma of the ovary (OPSC) and uterus (UPSC) are relatively uncommon malignancies with similar histological features. Information for their comparative behavior is lacking, hence a review was done to compare patterns of recurrence, disease-free and overall survival between the 2 groups. Methods: A retrospective review of 352 consecutive patients (pts) at a single institution with ovarian and uterine malignancies from 1991 through 2004 was done. Of these, 48 patients were identified with OPSC (n = 32) and UPSC (n = 16). To control surgeon as a prognostic fa
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9

Dörner, Marc, Mihai Ceanga, Frank Schreiber, et al. "High-Resolution Nerve Ultrasound Abnormalities in POEMS Syndrome—A Comparative Study." Diagnostics 11, no. 2 (2021): 264. http://dx.doi.org/10.3390/diagnostics11020264.

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Background: High-resolution nerve ultrasound (HRUS) has been proven to be a valuable tool in the diagnosis of immune-mediated neuropathies, such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) is an important differential diagnosis of CIDP. Until now, there have been no studies that could identify specific HRUS abnormalities in POEMS syndrome patients. Thus, the aim of this study was to assess possible changes and compare findings with CIDP patients. Methods: We retrospectively analyzed
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10

Slomovitz, Brian M., Russell R. Broaddus, Thomas W. Burke, et al. "Her-2/neu Overexpression and Amplification in Uterine Papillary Serous Carcinoma." Journal of Clinical Oncology 22, no. 15 (2004): 3126–32. http://dx.doi.org/10.1200/jco.2004.11.154.

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Purpose Uterine papillary serous carcinoma (UPSC) is an aggressive subtype of endometrial cancer characterized by early metastasis, resistance to therapy, and a high mortality rate. Little is known about the biology of these tumors. Smaller studies suggest that Her-2/neu may be involved in the tumorigenesis of this disease. The purpose of this study was to evaluate the protein expression and gene amplification of Her-2/neu in UPSC and to determine its prognostic value. Patients and Methods Tumor tissue from 68 patients with UPSC treated at The University of Texas M.D. Anderson Cancer Center fr
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11

Chang, W. C., B. C. Sheu, R. C. Chen, S. N. Chow, and S. C. Huang. "Depressed host immunity in a case of metachronous primary uterine papillary serous carcinoma and non-Hodgkin's lymphoma." International Journal of Gynecologic Cancer 14, no. 5 (2004): 1030–32. http://dx.doi.org/10.1136/ijgc-00009577-200409000-00043.

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Metachronous primary malignant tumors of uterine papillary serous carcinoma (UPSC) and non-Hodgkin's lymphoma (NHL) are rare. UPSC is a clinically aggressive and morphologically distinctive variant of endometrial carcinoma. We describe the clinical features of a 63-year-old patient with UPSC that was found 2 years after chemotherapy for malignant lymphoma of neck, stage IV and 5 months after radiation therapy for recurrence. This patient had undergone staging surgery and postoperative radiation for UPSC. One month after completion of radiotherapy, the patient expired due to persistence of the
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12

Shandilya, Gaurav Kumar. "Mental Health Status of UPSC CSE Aspirants: A Survey-Based Study." International Journal for Research in Applied Science and Engineering Technology 11, no. 5 (2023): 4454–58. http://dx.doi.org/10.22214/ijraset.2023.52603.

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Abstract: The Union Public Service Commission (UPSC) conducts one of the most challenging and competitive exams in India. Preparing for the UPSC exam requires immense hard work, dedication, and perseverance, which often puts a significant amount of stress on the aspirants' mental health. In this study, we conducted an online survey to assess the mental health status of UPSC aspirants. The survey was conducted on 203 participants, who were either preparing for the UPSC exam or had attempted it multiple times. The survey included questions on their attempts, coaching institutes, physical and men
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13

Memarzadeh, S., C. H. Holschneider, R. E. Bristow, et al. "FIGO stage III and IV uterine papillary serous carcinoma: Impact of residual disease on survival." International Journal of Gynecologic Cancer 12, no. 5 (2002): 454–58. http://dx.doi.org/10.1136/ijgc-00009577-200209000-00008.

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The objective of this study was to assess the impact of surgical cytoreduction on the survival of patients with uterine papillary serous carcinoma (UPSC). Patients added to the institutional tumor registries between January 1980 and September 2001 with the diagnosis of UPSC were reviewed. The records of 43 patients who underwent surgical cytoreduction for FIGO stage III and IV disease were reviewed. The median survival of UPSC patients with microscopic residual disease was significantly improved compared to those with macroscopic residual disease following primary surgical cytoreduction. We co
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14

Elit, Laurie, Andre LaRoche, Lauren Smith, et al. "Management of Women with Surgically Staged 1 Uterine Papillary Serous Cancer." ISRN Obstetrics and Gynecology 2011 (September 11, 2011): 1–9. http://dx.doi.org/10.5402/2011/146264.

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Objective. To review the management and outcomes of women with surgically staged 1 UPSC. Methods. We report on a case series from 2008–2010 from Hamilton Canada. We summarize the data from a literature search on surgically staged 1 UPSC. Results. There is a group women with Stage 1A UPSC with no residual disease at time of surgery who do not require adjuvant therapy. Vault recurrences appear to be lower in women who received adjuvant vault radiation. Chemotherapy appears to confer longer survival for those women with Stage 1B or 1C disease compared of those observed or who had radiation alone.
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15

McGunigal, Mary, Jerry Liu, Tamara Kalir, Manjeet Chadha, and Vishal Gupta. "Survival Differences Among Uterine Papillary Serous, Clear Cell and Grade 3 Endometrioid Adenocarcinoma Endometrial Cancers: A National Cancer Database Analysis." International Journal of Gynecologic Cancer 27, no. 1 (2016): 85–92. http://dx.doi.org/10.1097/igc.0000000000000844.

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ObjectivesHigh-risk histology including UPSC, CC, and high-grade (G3) endometrioid adenocarcinoma (EAC) have a worse prognosis compared to G1-2 EAC. It is unknown whether G3EAC outcomes are more similar to UPSC/CC or to G1-2 EAC. The purpose of this study was to compare overall survival (OS) among UPSC, CC, and G1-3 EAC, for International Federation of Gynecology and Obstetrics stages I to III.MethodsThe National Cancer Data Base was queried for patients diagnosed with International Federation of Gynecology and Obstetrics (1988 classification) Stage I-III UPSC, CC, and EAC from 1998 to 2012 wh
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16

Crain, Charles Nicolas, Remy Ngwanyam, and Gregory Punch. "Rare brain metastasis with unusual characteristics in a late recurrence of stage IIIA uterine papillary serous carcinoma." BJR|case reports 7, no. 4 (2021): 20200157. http://dx.doi.org/10.1259/bjrcr.20200157.

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Uterine papillary serous carcinoma (UPSC) is a rare endometrial neoplasm with high mortality rates. While the malignancy has often metastasized to distant organs by the time of diagnosis, brain lesions are extremely rare and most commonly only observed in widely disseminated disease. Here, we present an unusual case of UPSC with brain metastasis discovered six years after undergoing treatment for stage IIIA disease. Compared to the few previous cases of brain metastasis from UPSC, this lesion exhibited unusual imaging characteristics. We also highlight a potential imaging interpretation pitfal
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17

Seeber, Laura M. S., Ronald P. Zweemer, Luigi Marchionni, et al. "Methylation profiles of endometrioid and serous endometrial cancers." Endocrine-Related Cancer 17, no. 3 (2010): 663–73. http://dx.doi.org/10.1677/erc-10-0014.

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Promoter methylation is a gene- and cancer type-specific epigenetic event that plays an important role in tumour development. As endometrioid (endometrioid endometrial carcinoma, EEC) and serous endometrial cancers (uterine papillary serous carcinoma, UPSC) exhibit different clinical, histological and molecular genetic characteristics, we hypothesized that these differences may be reflected in epigenetic phenomena as well. Identification of a panel of methylation biomarkers could be helpful in a correct histological classification of these two subtypes, which solely on the basis of morphology
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18

Sjödin, Andreas, Max Bylesjö, Oskar Skogström, et al. "UPSC-BASE -Populustranscriptomics online." Plant Journal 48, no. 5 (2006): 806–17. http://dx.doi.org/10.1111/j.1365-313x.2006.02920.x.

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19

Peng, Xiangping, Shaoqing Li, Sidong Yang, et al. "Biomechanical Characterization of Unilateral and Bilateral Posterior Lumbar Interbody Fusion Constructs." BioMed Research International 2022 (August 13, 2022): 1–8. http://dx.doi.org/10.1155/2022/7081238.

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Study Design. Cadaveric biomechanical study. Objectives. To compare the biomechanical stability of two-level PLIF constructs with unilateral and bilateral pedicle screw fixations. Methods. Six cadaveric lumbar segments were evaluated to assess biomechanical stability in response to pure moment loads applied in flexion-extension (FE), lateral bending (LB), and axial rotation (AR). Each specimen was tested in six sequential configurations: (1) intact baseline; (2) facetectomy; (3) unilateral pedicle screws (UPS); (4) bilateral pedicle screws (BPS); (5) unilateral pedicle screws and cage (UPSC);
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He, Jing, Rui Shi, and Rimutu Ji. "Effect of Ultrasound Pre-Treatment on Extraction and Characterization of Collagen from Bactrian Camel Skin." Polymers 15, no. 8 (2023): 1943. http://dx.doi.org/10.3390/polym15081943.

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The objective of this study was to evaluate the effect of ultrasound pre-treatment on the characterization from Bactrian camel skin. It was possible to produce and characterize collagen extracted from Bactrian camel skin. The results showed that the yield of collagen was higher in ultrasound pre-treatment (UPSC) (41.99%) than the pepsin-soluble collagen extraction (PSC) (26.08%). All extracts were identified as type I collagens using sodium dodecyl sulfate polyacrylamide gel electrophoresis and retained their helical structure, as confirmed through Fourier transform infrared spectroscopy. The
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21

Holman, Laura L., David A. Iglesias, Pamela T. Soliman, et al. "Long-term survival in advanced-stage uterine papillary serous carcinoma." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5596. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5596.

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5596 Background: Advanced-stage (III/IV) uterine papillary serous carcinoma (UPSC) has a median overall survival (OS) of ~ 3 yrs. The study objective was to determine factors associated with long-term survival in advanced stage UPSC. Methods: We performed a retrospective review of pts diagnosed with stage III or IV UPSC between 1993 and 2012. Summary statistics were used to describe demographic and clinical characteristics. OS was estimated with the Kaplan-Meier estimator. Fisher’s exact test and the Wilcoxon rank sum test were used to compare pts surviving >3 yrs with those surviving <1
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Schmidt, Meirav, Yakir Segev, Rotem Sadeh, et al. "Cancer Antigen 125 Levels are Significantly Associated With Prognostic Parameters in Uterine Papillary Serous Carcinoma." International Journal of Gynecologic Cancer 28, no. 7 (2018): 1311–17. http://dx.doi.org/10.1097/igc.0000000000001300.

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ObjectivesUterine papillary serous carcinoma (UPSC) is a highly aggressive subtype of endometrial carcinoma. Histopathologically, it resembles the pattern of serous papillary carcinoma of the ovary. Cancer antigen 125 (CA-125) is the most widely used biomarker in epithelial ovarian carcinoma. Its use in UPSC evaluation has yet to be determined. The purpose of this study was to investigate the significance of preoperative serum CA-125 as a prognostic factor in patients with UPSC.MethodsThe study cohort included all women with UPSC operated in our institution between January 2002 and June 2016.
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Vaidya, A. P., R. Littell, C. Krasner, and L. R. Duska. "Treatment of uterine papillary serous carcinoma with platinum-based chemotherapy and paclitaxel." International Journal of Gynecologic Cancer 16, Suppl 1 (2006): 267–72. http://dx.doi.org/10.1136/ijgc-00009577-200602001-00043.

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Uterine papillary serous carcinoma (UPSC) is more aggressive than endometrioid endometrial cancer, as it often presents with advanced disease and follows a pattern of spread that resemblesthe serous carcinoma of the ovary. There exists little data on evaluating the combination of carboplatin and paclitaxel in UPSC. Institutional Review Board permission was obtained for a retrospective review. Tumor registry search was used to identify all patients with UPSC from 1990 to 2003. Charts were retrospectively evaluated from patients who had received at least three cycles of carboplatin and paclitaxe
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Ren, Yulan, Huaying Wang, Xiaoyan Zhou, et al. "Clinicopathological Characteristics and Her-2/neu Status in Chinese Patients with Uterine Papillary Serous Carcinoma." ISRN Obstetrics and Gynecology 2011 (October 20, 2011): 1–8. http://dx.doi.org/10.5402/2011/575327.

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Objective. To analyze clinico-pathological features of Chinese patients with UPSC, and investigate roles of Her-2/neu protein expression and gene amplification in UPSC prognosis. Methods. Thirty-six patients with UPSC treated in Cancer Hospital of Fudan University from 1996 to 2006 were analysed retrospectively. Chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) were performed to evaluate Her-2/neu gene amplification and protein expression respectively. Results. The median age was 63 years, and 61% (22/36) were late stages (stage III/IV). The 1-year, 3-year, and 5-year ove
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KASHIMA, K., Y. AOKI, T. YAHATA, and K. TANAKA. "Complete response to docetaxel and carboplatin combination chemotherapy for a stage IV uterine papillary serous carcinoma: a case report." International Journal of Gynecologic Cancer 15, no. 6 (2005): 1199–202. http://dx.doi.org/10.1136/ijgc-00009577-200511000-00039.

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We report a case of a stage IV uterine papillary serous carcinoma (UPSC) with multiple organ metastases. The patient was treated with docetaxel and carboplatin combination chemotherapy. After five courses, uterine tumor, Douglas tumor, lymphadenopathy, and distant metastases on magnetic resonance imaging or computed tomography scan were completely resoluted. Moreover, endometrial biopsy showed no carcinoma tissues after six courses. We suggest that this regimen may be effective for treatment of advanced-stage UPSC.
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Kato, Daniel T., Judith A. Ferry, Annekatheryn Goodman, et al. "Uterine Papillary Serous Carcinoma (UPSC)." Obstetrical & Gynecological Survey 51, no. 4 (1996): 229–30. http://dx.doi.org/10.1097/00006254-199604000-00014.

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27

Gupta, Divya, Marc J. Gunter, Kathleen Yang, et al. "Performance of Serum CA125 as a Prognostic Biomarker in Patients With Uterine Papillary Serous Carcinoma." International Journal of Gynecologic Cancer 21, no. 3 (2011): 529–34. http://dx.doi.org/10.1097/igc.0b013e31821091b5.

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HypothesisSerum CA125 is a potential biomarker for metastatic disease and recurrence in patients with uterine papillary serous carcinoma (UPSC).MethodsAll patients with UPSC who had preoperative CA125 measurement and surgical staging between 1998 and 2008 at the participating institutions were included in this analysis (N = 52). Data were extracted from patients' records. Fisher exact and χ2tests were used to assess the association of CA125 levels with clinical and pathological variables. The correlation between CA125 levels (high/low) and lymph node metastases (positive/negative) was evaluate
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28

Tangirala, Maruthi P. "UPSC: Civil Services Examination and Beyond." Indian Journal of Public Administration 56, no. 4 (2010): 920–32. http://dx.doi.org/10.1177/0019556120100407.

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Viswanathan, A., N. Horick, C. Tanaka, S. Campos, U. Matulonis, and R. Berkowitz. "Chemotherapy and radiation therapy in UPSC." Journal of Clinical Oncology 25, no. 18_suppl (2007): 5535. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5535.

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5535 Purpose: To analyze the impact of chemotherapy (Ch) and radiation therapy (RT) on relapse rates in patients with uterine papillary serous carcinoma (UPSC). Materials and Methods: The outcomes of 160 women with UPSC seen between 1980–2005 at the BW/DFCC were analyzed. Exclusion criteria included stage IVB disease, no hysterectomy, unknown stage, or unknown type of RT. Results: The median age was 67 years (range 31–90). FIGO Stage was IA (21), IB (28), IC (13), IIA (7), IIB (10), IIIA (42), IIIB (2), IIIC (21), and IVA (16). Treatment included none (40), Ch alone (20), Ch and whole abdomina
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Villella, J. A., S. Cohen, D. H. Smith, H. Hibshoosh, and D. Hershman. "HER‐2/neuoverexpression in uterine papillary serous cancers and its possible therapeutic implications." International Journal of Gynecologic Cancer 16, no. 5 (2006): 1897–902. http://dx.doi.org/10.1136/ijgc-00009577-200609000-00027.

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Uterine papillary serous carcinoma (UPSC) is a highly aggressive variant of endometrial cancer with features similar to high-grade ovarian cancer. Patients tend to be elderly, thin, have a high grade tumor with extensive extrauterine disease at the time of diagnosis. The transmembrane receptor encoded by the HER-2 cellular oncogene is amplified in several types of human carcinomas and provides an attractive therapeutic target. HER-2/neu, the transmembrane receptor encoded by the c-erbB2 gene, is overexpressed by immunohistochemistry in <25% of ovarian cancers and 20–30% of breast cancers, a
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Boyraz, Gokhan, Mehmet Coskun Salman, Derman Basaran, et al. "Extrauterine Spread, Adjuvant Treatment, and Prognosis in Noninvasive Uterine Papillary Serous Carcinoma of the Endometrium: A Retrospective Multicenter Study." International Journal of Gynecologic Cancer 27, no. 1 (2016): 102–8. http://dx.doi.org/10.1097/igc.0000000000000838.

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ObjectivesThe aim of this retrospective multicenter study was to investigate the frequency of extrauterine metastasis and to evaluate the importance of surgical staging and adjuvant treatment among patients with noninvasive uterine papillary serous carcinoma (UPSC) of the endometrium.Materials and MethodsA multicenter, retrospective department database review was performed to identify patients with UPSC of the endometrium who underwent surgical staging between 2000 and 2015 at 4 Gynecologic Oncology Centers in Turkey. Demographic, clinicopathological, and survival data were collected.ResultsA
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Lin, Jeff Feng-Hsu, Paniti Sukumvanich, Keila Parada, et al. "Multimodal therapy in patients with node-positive (stage IIIC) uterine papillary serous carcinoma: A National Cancer Database study." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5585. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5585.

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5585 Background: Uterine papillary serous carcinoma (UPSC) is an aggressive endometrial cancer that carries a 30-40% risk of nodal metastasis. Adjuvant systemic chemotherapy has become standard of care in advanced UPSC, but the role of additional adjuvant radiotherapy is unclear. This study aims to evaluate survival outcomes of multimodal therapy through the use of the National Cancer Data Base (NCDB). Methods: All patients diagnosed with surgically-staged FIGO stage IIIC uterine papillary serous carcinoma were identified in the NCDB from 1/1998 through 12/2010. Patients were divided into thos
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LaDousa, Chaise. "Language medium and a high-stakes test: Language ideology and coaching centers in North India." International Journal of the Sociology of Language 2018, no. 253 (2018): 103–24. http://dx.doi.org/10.1515/ijsl-2018-0025.

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Abstract The Union Public Service Commission (UPSC) offers its set of examinations in a “medium”, whether in a language recognized by the Constitution of India or in English. The notion of medium in the examination borrows from the notion of medium in schooling where it refers to the primary language of pedagogy. Although not all students who have studied in a particular medium in school and university go on to attempt the UPSC examinations in the same medium, most do. This article reports on fieldwork conducted in 2014 in coaching centers in Delhi’s Mukherjee Nagar and in the city of Varanasi
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Steed, H., L. Manchul, B. Rosen, et al. "Uterine papillary serous carcinoma: evaluation of multimodality treatment with abdominopelvic radiotherapy and chemotherapy." International Journal of Gynecologic Cancer 16, Suppl 1 (2006): 278–85. http://dx.doi.org/10.1136/ijgc-00009577-200602001-00045.

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The aim of this study was to compare overall survival (OS), progression-free survival (PFS), and relapse patterns between different modalities of treatment for uterine papillary serous carcinoma (UPSC). A retrospective review of 124 patients with pathologically confirmed UPSC was performed, of whom, 97 patients were eligible for study. Postoperative treatment groups included adjuvant radiotherapy consisting of whole abdomen and a pelvic boost (abdominopelvic radiotherapy [APRT]) (55 patients), paclitaxel and carboplatin chemotherapy (CT) for six cycles followed by APRT (18 patients), CT only (
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Semer, D., N. P. Nguyen, S. Sallah, et al. "Prognosis for papillary serous carcinoma of the endometrium after surgical staging." International Journal of Gynecologic Cancer 11, no. 4 (2001): 305–11. http://dx.doi.org/10.1136/ijgc-00009577-200107000-00009.

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Abstract.Nguyen NP, Sallah S, Karlsson U, Vos P, Ludin A, Semer D, Tait D, Salehpour M, Jendrasiak G, Robiou C. for papillary serous carcinoma of the endometrium after surgical staging.Background: To investigate the pattern of failure and the prognosis following pathological staging for uterine papillary serous carcinoma (UPSC).Patients and methods: A retrospective review was conducted of 22 patients with UPSC, treated between 1989 and 1998 at a single institution. All patients were surgically staged. Two patients with advanced disease received chemotherapy only. Two patients with early-stage
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Roelofsen, Thijs, Marjanka Mingels, Jan C. M. Hendriks, et al. "Preoperative CA-125 predicts extra-uterine disease and survival in uterine papillary serous carcinoma patients." International Journal of Biological Markers 27, no. 3 (2012): 263–71. http://dx.doi.org/10.5301/jbm.2012.9346.

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Objective We determined the clinical utility of preoperative serum CA-125 as predictor of extra-uterine disease and as prognosticator for survival in patients with uterine papillary serous carcinoma (UPSC). Methods Patients diagnosed with UPSC, identified between 1992 and 2009, and with preoperative CA-125 measurement were included. A receiver operator characteristic (ROC) curve was used to quantify marker performance. Overall and progression free survival were analyzed using the Kaplan-Meier method. Regression analyses were used to investigate the association of preoperative CA-125 levels and
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Hoang, Nhat-Duc, Duy-Thang Vu, Xuan-Linh Tran, and Van-Duc Tran. "Modeling Punching Shear Capacity of Fiber-Reinforced Polymer Concrete Slabs: A Comparative Study of Instance-Based and Neural Network Learning." Applied Computational Intelligence and Soft Computing 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/9897078.

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This study investigates an adaptive-weighted instanced-based learning, for the prediction of the ultimate punching shear capacity (UPSC) of fiber-reinforced polymer- (FRP-) reinforced slabs. The concept of the new method is to employ the Differential Evolution to construct an adaptive instance-based regression model. The performance of the proposed model is compared to those of Artificial Neural Network (ANN) and traditional formula-based methods. A dataset which contains the testing results of FRP-reinforced concrete slabs has been collected to establish and verify new approach. This study sh
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Baek, Min-Hyun, Shin-Wha Lee, Jeong-Yeol Park, et al. "Identification of a Preoperative Predictive Factor for Lymph Node Metastasis in Uterine Papillary Serous Carcinoma: Long-term Results From a Single Institution." International Journal of Gynecologic Cancer 25, no. 1 (2015): 69–74. http://dx.doi.org/10.1097/igc.0000000000000318.

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ObjectiveThe purpose of this study was to identify preoperative clinicopathological predictive factors for lymph node (LN) metastasis in women diagnosed with uterine papillary serous carcinoma (UPSC).MethodsWomen diagnosed with UPSC in our institution from 1997 to 2012 were identified. All patients underwent hysterectomy and bilateral salpingo-oophorectomy plus pelvic and/or para-aortic lymphadenectomy. The predictive values of the risk factors for LN metastasis were analyzed using χ2 and multivariate logistic regression analyses.ResultsA total of 94 patients met our study criteria. A CA-125 c
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Hong, Julian C., Jonathan Foote, Gloria Broadwater, Stéphanie Gaillard, Laura J. Havrilesky, and Junzo P. Chino. "Impact of Chemotherapy and Radiotherapy on Management of Early Stage Clear Cell and Papillary Serous Carcinoma of the Uterus." International Journal of Gynecologic Cancer 27, no. 4 (2017): 720–29. http://dx.doi.org/10.1097/igc.0000000000000926.

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ObjectiveThe aim of the study was to assess interaction of lymph node dissection (LND), adjuvant chemotherapy (CT), and radiotherapy (RT) in stage I uterine papillary serous carcinoma (UPSC) and uterine clear cell carcinoma (UCC).Methods/MaterialsThe National Cancer Data Base was queried for women diagnosed with International Federation of Gynecology and Obstetrics stage I UPSC and UCC from 1998 to 2012. Overall survival (OS) was estimated for combinations of RT and CT by the Kaplan-Meier method stratified by histology and LND. Multivariate Cox proportional hazard models were generated.Results
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Growdon, Whitfield B., J. Jose A. Rauh-Hain, Adriana Cordon, et al. "Prognostic Determinants in Patients With Stage I Uterine Papillary Serous Carcinoma: A 15-Year Multi-Institutional Review." International Journal of Gynecologic Cancer 22, no. 3 (2012): 417–24. http://dx.doi.org/10.1097/igc.0b013e31823c6e36.

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ObjectiveThe aim of this retrospective, multi-institutional study was to evaluate the importance of surgical staging for stage I uterine papillary serous carcinomas (UPSCs) to determine optimal management of this rare tumor.MethodsWith institutional review board approval from both participating institutions, all patients with 2009 International Federation of Gynecology and Obstetrics stage I mixed serous and UPSC diagnosed between January 1, 1992, and December 31, 2007, were identified at the 2 institutions. Clinical factors were correlated using Spearman correlation coefficients, Kaplan-Meier
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Huh, W. K. "What is the correct management of stage i UPSC?" International Journal of Gynecological Cancer 15, no. 2 (2005): 405–6. http://dx.doi.org/10.1111/j.1525-1438.2005.abst_13.x.

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Hamilton, C. A., M. M. Zhang, J. K. Chan, et al. "A preclinical study of cellular immunotherapy redirected by bispecific antibodies in uterine cell lines and primary cancer cells." Journal of Clinical Oncology 24, no. 18_suppl (2006): 15044. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.15044.

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15044 Background: Cytokine induced killer cells (CIKs) are ex-vivo activated and expanded CD8+ natural killer T cells that have been shown to have cytotoxic activity against cancers in randomized clinical trials. We determined the cytotoxic activity of CIK cells against endometrioid and serous papillary (UPSC) uterine cancer cell lines and evaluated the ability of Trastuzumab and Her2xCD3 bispecific antibodies to enhance CIK-mediated cytotoxicity in Her2/neu expressing uterine cancer cells. Methods: The cytotoxicity of CIKs was quantified by 4-hour 51Cr release assays against uterine cell line
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Huh, W. K. "WHAT IS THE CORRECT MANAGEMENT OF STAGE I UPSC?: 0013." International Journal of Gynecologic Cancer 15, no. 2 (2005): 405.3–406. http://dx.doi.org/10.1136/ijgc-00009577-200503000-00049.

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Bracchiglione, Javier, Gerardo Rodríguez-Grijalva, Carolina Requeijo, et al. "Systemic Oncological Treatments versus Supportive Care for Patients with Advanced Hepatobiliary Cancers: An Overview of Systematic Reviews." Cancers 15, no. 3 (2023): 766. http://dx.doi.org/10.3390/cancers15030766.

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Background: The trade-off between systemic oncological treatments (SOTs) and UPSC in patients with primary advanced hepatobiliary cancers (HBCs) is not clear in terms of patient-centred outcomes beyond survival. This overview aims to assess the effectiveness of SOTs (chemotherapy, immunotherapy and targeted/biological therapies) versus UPSC in advanced HBCs. Methods: We searched for systematic reviews (SRs) in PubMed, EMBASE, the Cochrane Library, Epistemonikos and PROSPERO. Two authors assessed eligibility independently and performed data extraction. We estimated the quality of SRs and the ov
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Chambers, J. T., M. Merino, E. I. Kohorn, P. E. Peschel, and P. E. Schwartz. "Uterine papillary serous carcinoma (UPSC) at Yale-New Haven Hospital (YNHH)." Gynecologic Oncology 23, no. 2 (1986): 262. http://dx.doi.org/10.1016/0090-8258(86)90277-5.

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Kato, Daniel T., Judith A. Ferry, Annekathryn Goodman, et al. "Uterine Papillary Serous Carcinoma (UPSC): A Clinicopathologic Study of 30 Cases." Gynecologic Oncology 59, no. 3 (1995): 384–89. http://dx.doi.org/10.1006/gyno.1995.9957.

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KHAN, Dr NABEE, and Dr VENUDHAR ROUTIYA. "ESTABLISHING A CENTRALIZED RECRUITMENT COMMISSION FOR ACADEMIC STAFF IN INDIA: A COMPARATIVE ANALYSIS OF CURRENT PRACTICES AND THE NEED FOR STANDARDIZATION." International Journal of Social Sciences and Management Review 07, no. 05 (2024): 123–37. http://dx.doi.org/10.37602/ijssmr.2024.7510.

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The recruitment of academic staff in India’s higher education sector currently lacks a centralized, standardized approach, leading to significant inconsistencies, transparency issues, and potential biases in the hiring process. While the Union Public Service Commission (UPSC) and State Public Service Commissions (SPSCs) provide a structured and merit-based recruitment model for civil and administrative officers, no such unified mechanism exists for academic staff in Central and State universities and colleges. This research paper explores the shortcomings of the current decentralized recruitme
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La Fianza, Alfredo, Elisa Alberici, Enrico Maria Di Maggio, Lorenzo Preda, and Rodolfo Campani. "Multiple nodular metastases in mesenteric panniculitis by uterine papillary serous adenocarcinoma (upsc):." Clinical Imaging 23, no. 2 (1999): 90–93. http://dx.doi.org/10.1016/s0899-7071(98)00092-8.

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Slomovitz, Brian M., Thomas W. Burke, Patricia J. Eifel, et al. "Uterine papillary serous carcinoma (UPSC): a single institution review of 129 cases." Gynecologic Oncology 91, no. 3 (2003): 463–69. http://dx.doi.org/10.1016/j.ygyno.2003.08.018.

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Fader, Amanda Nickles, David Starks, Paola A. Gehrig, et al. "An updated clinicopathologic study of early-stage uterine papillary serous carcinoma (UPSC)." Gynecologic Oncology 115, no. 2 (2009): 244–48. http://dx.doi.org/10.1016/j.ygyno.2009.07.030.

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