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1

Stansbridge, Elizabeth M., Damian G. Griffin, and Valerie Walker. "Who makes uric acid stones and why—observations from a renal stones clinic." Journal of Clinical Pathology 66, no. 5 (2013): 426–31. http://dx.doi.org/10.1136/jclinpath-2012-201373.

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AimsExcessively acidic urine is the dominant factor in uric acid stone formation. Recent evidence implicating insulin resistance has revived interest in its causation. We reviewed data on uric acid stone formers attending a general stones clinic to find out whether this supports and adds to current concepts.MethodsA retrospective database study of 1504 stone formers investigated at the Southampton renal stones clinic from 1990 to March 2007. Uric acid stone formers and idiopathic calcium stone formers were compared using non-parametric tests.ResultsFifty-nine patients (3.9%; 43 men) had uric a
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2

Ma, Qi, Li Fang, Rui Su, Liang Ma, Guohai Xie, and Yue Cheng. "Uric acid stones, clinical manifestations and therapeutic considerations." Postgraduate Medical Journal 94, no. 1114 (2018): 458–62. http://dx.doi.org/10.1136/postgradmedj-2017-135332.

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Uric acid stones account for 10%–15% of all urinary stones. Changes in dietary habits, environment or both can result in the increase of uric acid stones. The formation of uric acid stones is related to hyperuricosuria, low urinary volume and persistently low urinary pH. Diabetes and obesity also significantly increase the risk of stone formation. Dual-energy CT provides a convenient and reliable method for diagnosis. Stone composition analysis and 24-hour urine metabolic evaluations should be considered for further evaluation. Most small uric acid stones (diameter <2 cm) can be treated by
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3

Cicerello, Elisa. "Uric acid nephrolithiasis: An update." Urologia Journal 85, no. 3 (2018): 93–98. http://dx.doi.org/10.1177/0391560318766823.

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Uric acid nephrolithiasis appears to increase in prevalence. While a relationship between uric acid stones and low urinary pH has been for long known, additional association with various metabolic conditions and pathophysiological basis has recently been elucidated. Some conditions such as diabetes and metabolic syndrome disease, excessive dietary intake, and increased endogenous uric acid production and/or defect in ammoniagenesis are associated with low urinary pH. In addition, the phenomenon of global warming could result in an increase in areas with greater climate risk for uric acid stone
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4

Pricop, Cătălin, Marius Ivănuță, Mihaela Nikolic, and Dragoş Puia. "Kidney Stones of Type I vs. Type II Diabetic Patients: Are There Any Differences?" Journal of Clinical Medicine 13, no. 20 (2024): 6110. http://dx.doi.org/10.3390/jcm13206110.

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Background: This study highlighted the differences between the biochemical compositions of urinary stones from patients with type 1 diabetes versus those with type 2 diabetes. Materials and Methods: This study included patients diagnosed with kidney stones and diabetes who were referred to the Urological Clinic of the Dr. C. I. Parhon Hospital in Iasi from April 2017 to April 2024. We analyzed the spectroscopic stone composition from 128 lithiasis patients treated in our Clinic. In the current study, the distribution of the biochemical composition of stones varied significantly between diabeti
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Sholan, Rashad, Rufat Aliyev, Ulduz Hashimova, Seymur Karimov, and Elvin Bayramov. "Urinary Stone Composition Analysis of 1465 Patients: The First Series from Azerbaijan." Archives of Iranian Medicine 27, no. 11 (2024): 618–23. http://dx.doi.org/10.34172/aim.32026.

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Background: Urinary stone disease is a prevalent health issue worldwide, with varying incidence influenced by multiple factors. This study aims to provide the first comprehensive analysis of urinary stone composition in Azerbaijan. Methods: A retrospective study was conducted on 1465 patients, aged 1‒83 years, who underwent biochemical urinary stone analysis at the Department of Renal Diseases and Organ Transplantation, Azerbaijan State Security Service Military Hospital, between April 2015 and December 2023. Stone samples were analyzed using Fourier transform infrared (FTIR) spectroscopy. Sta
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Fernandez, Alfonso, Andrew Fuller, Reem Al-Bareeq, Linda Nott, and Hassan Razvi. "A comparison of the metabolic profiles of diabetic and non-diabetic uric acid stone formers." Canadian Urological Association Journal 7, no. 3-4 (2013): e190-2. http://dx.doi.org/10.5489/cuaj.820.

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Introduction: The aim of this study was to compare the metabolic profiles of diabetic and non-diabetic patients with uric acid stones to understand whether preventive strategies should be tailored to reflect different causative factors.Methods: The results of the metabolic evaluation of patients with uric acid stones identified prospectively from the Metabolic Stone Clinic at St. Joseph’s Hospital, London, Canada were reviewed. Information included patients’ clinical histories, 24 hour urine collections, blood chemistry and stone analysis.Results: Complete data were obtained from 68 patients w
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7

Kim, Jong, Kang Cho, Do Kim, Doo Chung, Hae Jung, and Joo Lee. "Predictors of Uric Acid Stones: Mean Stone Density, Stone Heterogeneity Index, and Variation Coefficient of Stone Density by Single-Energy Non-Contrast Computed Tomography and Urinary pH." Journal of Clinical Medicine 8, no. 2 (2019): 243. http://dx.doi.org/10.3390/jcm8020243.

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We analyzed the capacities of pertinent parameters (determined by single-energy non-contrast computed tomography [NCCT]) and urinary pH to predict uric acid stones. We reviewed the medical records of 501 patients whose stones were removed surgically or passed spontaneously between December 2014 and April 2016. Qualifying participants (n = 420) were stratified by the nature of the stone (calcium oxalate, uric acid, or infectious). Based on NCCT, we determined maximal stone length (MSL), mean stone density (MSD), and stone heterogeneity index (SHI) using Hounsfield units (HU) and calculated the
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8

Safranow, Krzysztof, and Zygmunt Machoy. "Methylated Purines in Urinary Stones." Clinical Chemistry 51, no. 8 (2005): 1493–98. http://dx.doi.org/10.1373/clinchem.2005.048033.

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Abstract Background: The aim of the study was to measure the content of methylated purines that appear as admixtures in uric acid stones. Methods: We analyzed urinary calculi from 48 residents of Western Pomerania who underwent surgery at the urology ward in Szczecin. Stone samples were dissolved in 0.1 mol/L NaOH. Extracts were diluted in 50 mmol/L KH2PO4 and analyzed by reversed-phase HPLC with ultraviolet detection and use of a gradient of methanol concentration and pH. Results: Uric acid was the main component of 9 stones. All 9 showed admixtures of 9 other purine derivatives: endogenous p
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9

Golovanov, S. A., M. Yu Prosyannikov, A. V. Sivkov, N. V. Anokhin, D. A. Voytko, and V. V. Drozhzheva. "Metabolic risk factors and urinary stones formation. IX: Lithogenic features of monomineral and mixed stones in men and women." Experimental and Сlinical Urology 17, no. 2 (2024): 68–80. http://dx.doi.org/10.29188/2222-8543-2024-17-2-68-80.

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Introduction. The study of lithogenic substances excretion in stone formers with pure monomineral stones allows us to identify characteristic metabolic changes, the long-term effect of which determines the originality of the pathogenetic mechanism features of the formation of urinary stones consisting of pure minerals. The problem of studying lithogenesis of «pure» (monomineral) stones in stone formers is of great clinical importance, since it assumes the existence of various approaches to prevention and metaphylaxis of urolithiasis in patients with «pure» stones and mixed stones. Materials an
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10

Becker, Gavin. "Uric acid stones." Nephrology 12, s1 (2007): S21—S25. http://dx.doi.org/10.1111/j.1440-1797.2007.00774.x.

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11

Hali´nski, Adam, Kamran Hassan Bhatti, Luca Boeri, et al. "Stone composition of renal stone formers from different global regions." Archivio Italiano di Urologia e Andrologia 93, no. 3 (2021): 307–12. http://dx.doi.org/10.4081/aiua.2021.3.307.

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Objective: To study urinary stone composition patterns in different populations around the world. Materials and methods: Data were collected by reviewing charts of 1204 adult patients of 10 countries with renal or ureteral stones (> 18 years) in whom a stone analysis was done and available. Any method of stone analysis was accepted, but the methodology had to be registered. Results: In total, we observed 710 (59%) patients with calcium oxalate, 31 (1%) with calcium phosphate, 161 (13%) with mixed calcium oxalate/calcium phosphate, 15 (1%) with carbapatite, 110 (9%) with uric acid, 7 (< 1
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12

Liu, Chan Jung, Jin Shang Wu, and Ho Shang Huang. "Decreased Associated Risk of Gout in Diabetes Patients with Uric Acid Urolithiasis." Journal of Clinical Medicine 8, no. 10 (2019): 1536. http://dx.doi.org/10.3390/jcm8101536.

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Uric acid urolithiasis constitutes approximately 7–10% of all urinary stones. Previous studies have revealed that patients with gout do not equally have uric acid stones. Instead, the risk of gout in patients with uric acid stones remains controversial. This study aimed to investigate whether there is different associated risk of gout for diabetes mellitus (DM) and non-diabetes patients with uric acid urolithiasis. Therefore, we examined all baseline chemistries to determine any risk factors or protective factors related to developing gout in patients with uric acid stones. Ninety-nine patient
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13

Prosiannikov, Michail Y., Nikolay V. Anokhin, Sergey A. Golovanov, Olga V. Konstantinova, Andrey V. Sivkov, and Oleg I. Apolihin. "Urine stones of different chemical composition occurrence depending on the level of uricuria." Urology reports (St. - Petersburg) 10, no. 2 (2020): 107–13. http://dx.doi.org/10.17816/uroved102107-113.

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Introduction. According to modern concepts one of the key links in the pathogenesis of urolithiasis is metabolic lithogenic disturbances. The study of the complex effect of many factors on the metabolism of urolithiasis patient is the basis of modern scientific research. We studied the frequency of various chemical urinary stones occurrence depending on various levels of uricuria.
 Materials and methods. Data from of 708 urolithiasis patients (303 men and 405 women) were analized. The results of blood and urine biochemical analysis and chemical composition of urinary stone were studied. T
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14

Yadav, Baidyanath, and Surendra Maharjan. "Characterization of Urinary Tract Stones with Dual Energy Computed Tomography." Radiography Open 3, no. 1 (2017): 11. http://dx.doi.org/10.7577/radopen.2001.

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Introduction. Dual Energy Computed Tomography (DECT) scan can provides simple and reliable differentiation between uric acid and non-uric acid stones. The characterization of various stones was based on the dual energy ratio and x-ray attenuation or HU. Methodology. A prospective study was conducted among 101 adult patients in Tribhuvan University Teaching Hospital (TUTH), Nepal. Informed written consent was obtained from all the participants. The standard low doses CT KUB were performed in multi-slice CT scanner (Siemens Somatom Definition AS+ 128 slice) at 120 kVp and 250 mAs. When stones we
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15

Tanemoto, M., Y. Takeuchi, E. Mishima, T. Suzuki, T. Abe, and S. Ito. "Urinary stones resembling uric acid stones." Clinical Kidney Journal 3, no. 3 (2010): 318–19. http://dx.doi.org/10.1093/ndtplus/sfq008.

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16

Jean, SOSSA, and AVAKOUDJO Dedjinnin Josue Georges. "The Chemical Compositon of Urinary Stones at the Military Teaching Hospital of Cotonou." SAS Journal of Surgery 7, no. 10 (2021): 549–52. http://dx.doi.org/10.36347/sasjs.2021.v07i10.005.

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The Chemical composition of urinary stones at the Military Teaching Hospital of Cotonou. Objective: To determine the chemical composition of urinary stones in our patients. Patients and method: We collect surgically removed urinary stones from our patients and send them abroad for infrared spectroscopic analysis. Results: The infrared spectroscopic analysis was performed on urinary stones from 26 patients, i.e. 21 males (80.8%) and 5 females (19.2%). Their mean age was 48 years (range: 21-71). The mean proportions of chemical components in the stones were: 40.8% whewellite (0-97), 29.4% weddel
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17

Kamel, K. S., S. Cheema-Dhadli, M. A. Shafiee, M. R. Davids, and M. L. Halperin. "Recurrent uric acid stones." QJM 98, no. 1 (2004): 57–68. http://dx.doi.org/10.1093/qjmed/hci008.

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18

Sreedharan, Jayadevan, LJ John, HAM Aly Freeg, and J. Muttappallymyalil. "Urolithiasis in male patients: A pilot study on the ethnic differences and clinical profile." Nepal Journal of Epidemiology 4, no. 4 (2014): 393–98. http://dx.doi.org/10.3126/nje.v4i4.11359.

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Background Ethnicity play a role in the occurrence of urinary stones, probably related to climatic, environmental and dietary factors in ethnic groups. The association between ethnicity, age, clinical profile, stone size with type of ureteric stones among males with urolithiasis was studied. Materials and Methods Male patients (>18 years) with lower ureteral stones size <10mm attending outpatient department of Urology, at a private hospital, Ajman over a period of one year were included. Ethics approval was obtained from Institutional Ethics Committee. Data was retrieved from the case re
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19

Khalid, Farah, and Saadiyah Ahmed Dhahir. "Evaluation of Minerals and some Biochemical parameters in the serum of Renal stones from Iraqi patients." Iraqi Journal for Applied Sciences 1, no. 3 (2024): 11–16. https://doi.org/10.69923/qmt17g10.

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Urolithiasis is a Global health issue, a frequent and painful illness involving kidney or urinary tract stones. Anatomical, environmental, genetic, viral, metabolic, dietary, and socioeconomic variables are among its causes. There is a 50% chance of recurrence within five years, and the frequency varies between 4 and 20% worldwide. This study aims to correlate stone composition with blood biochemical parameters in urolithiasis patients. 85 blood samples were collected and divided between 45 patients with kidney stones and 40 controls. Urea, uric acid, creatinine, GFR, calcium, sodium, and phos
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20

Tsaturyan, Arman, Elizaveta Bokova, Piet Bosshard, Olivier Bonny, Daniel G. Fuster, and Beat Roth. "Oral chemolysis is an effective, non-invasive therapy for urinary stones suspected of uric acid content." Urolithiasis 48, no. 6 (2020): 501–7. http://dx.doi.org/10.1007/s00240-020-01204-8.

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AbstractDespite the possible benefit from avoiding stone surgery with all its possible complications, oral chemolysis is rarely performed in patients with urinary stones suspected of uric acid content. Among the reasons for its limited use is the sparse and low-quality data on its efficacy and the lack of reliable factors predicting its outcome. We thus performed a retrospective single-center cohort study of 216 patients (median patient age 63 years) with 272 renal (48%) and/or ureteral (52%) stones treated with oral chemolysis from 01/2010 to 12/2019. Patients with low urine pH (< 6), low
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21

Barbera, Michele, Andreas Tsirgiotis, Mauro Barbera, and Quintino Paola. "The importance of potassium citrate and potassium bicarbonate in the treatment of uric acid renal stones." Archivio Italiano di Urologia e Andrologia 88, no. 4 (2016): 341. http://dx.doi.org/10.4081/aiua.2016.4.341.

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Uric acid calculi can also be treated without surgery, with simple medical lytic therapy. After appropriate dietary adjustments and add of mineral water, the needed amount of alkali supplementation can increase pH values of the urine in order to dissolve the stones. Treatment should be prolonged to prevent stone recurrence. A case of bilateral renal uric acid stones that were successfully treated by alakalizing treatment was presented.
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Saleh, IshraqAbdulrrazaq, Ali Hazim Abdulkareem, and Ziad Hamad Abd. "Chemical Analysis Study of Kidney Stones in Iraqi Community." NeuroQuantology 20, no. 5 (2022): 844–48. http://dx.doi.org/10.14704/nq.2022.20.5.nq22242.

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The urinary tract system is one of the most important system in human body to control many functions and get any wastes out of body, many diseases may affect this function and prevents it to work effectively. One of this disease is nephrolithiasis at which salt forming stone are settled in renal system affecting its work. The qualitative biochemical analysis of compositions of each stone was done for carbonate, calcium, magnesium, phosphate, oxalate, uric acid, and cysteine, using stone powder derived from the stones. These results found that Calcium oxalate stones were more likely to be detec
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Alharbi, Abdallah Saud, Moawia Gameraddin, Awadia Gareeballah, et al. "Assessment of Hounsfield Units and Factors Associated with Fragmentation of Renal Stones by Extracorporeal Shock Wave Lithotripsy: A Computerized Tomography Study." Tomography 10, no. 1 (2024): 90–100. http://dx.doi.org/10.3390/tomography10010008.

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The success rate of extracorporeal shock wave lithotripsy (ESWL) is influenced by various factors, including stone density, and is determined through computed tomography scans in terms of Hounsfield units (HU). Materials and Methods: This retrospective single-center study was conducted in the King Fahad Hospital. Sixty-seven adult patients with renal and ureteric stones were selected randomly and enrolled in the study. Their ages ranged from 20 to 69 years. The patients were examined with non-contrast enhancement (NCCT) to assess the HU of their stones and were consequently treated with ESWL.
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Manish, Bhatt, Ujaskumar Ashvinbhai Patel, Abbas Shakir Hussain Sabunwala Ali, and Saini Rishabh. "Spectrum of Renal Calculi Composition in Southern Rajasthan Using Infrared Spectroscopy." International Journal of Toxicological and Pharmacological Research 13, no. 9 (2023): 63–66. https://doi.org/10.5281/zenodo.11079963.

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<strong>Introduction:</strong>&nbsp;The aim of this study was to evaluate the chemical composition of urinary stones and pattern of changes according to the patient&rsquo;s age in Southern Rajasthan using infrared spectroscopy (IRS).&nbsp;<strong>Materials and Methods:</strong>&nbsp;A prospective study of 500 urolithiasis patients was carried out in a tertiary care center from August 2021 to August 2023. Chemical composition of urinary stones was analyzed using IR spectroscopy, and a subgroup study based on the patient&rsquo;s age was done (8&ndash;12 years &ndash; Group A, 13&ndash;18 years &
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Baresi, A., S. De Cenzo, R. Bonacina, and S. Perego. "Instrumental chemiolysis of uric acid stones in high risk patients." Urologia Journal 62, no. 1_suppl (1995): 97–99. http://dx.doi.org/10.1177/039156039506201s26.

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— The Authors report a series of 15 reno-ureteral obstructive uric acid calculi in high risk patients initially treated by percutaneous nephrostomy. After attempting stone dissolution by in-situ alkalinization, they discuss the place of such a method among the various treatments for uric acid stones.
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Bhawani, Shafqat Shabir, Majid Jehangir, Mohammad Masood, Sajjad Ahmad Dar, and Sajad Nazir Syed. "Dual-Energy Multidetector Computed Tomography: A Highly Accurate Non-Invasive Tool for in Vivo Determination of Chemical Composition of Renal Calculi." Galician Medical Journal 28, no. 3 (2021): E202134. http://dx.doi.org/10.21802/gmj.2021.3.4.

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Introduction. Computed tomography is more accurate than excretory urography in evaluation of renal stones due to its high sensitivity and temporal resolution; it permits sub-millimetric evaluation of the size and site of calculi but cannot evaluate their chemical composition. Dual-energy computed tomography allows evaluating the chemical composition of urinary calculi using simultaneous image acquisition at two different energy levels.&#x0D; The objective of the research was to determine renal stone composition using dual-energy multidetector computed tomography, and its correlation with post-
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AJ, Jahangiri, and Moghaddam AM. "Dual Energy Computed Tomography and Effect on the Management of Uric Acid Renal Calculi." Journal of Radiation and Nuclear Medicine 1, no. 2 (2023): 13–18. http://dx.doi.org/10.14302/issn.2766-8630.jrnm-22-4093.

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Attenuation differences from 2 x-ray sources allow differentiation and characterization of stone types with similar radiation dose compared to single-energy CT scan. The difference is shown in colours, allowing preoperative prediction and management of stones. We determined the effect of DECT-KUB on urological management of patients with uric acid stones since it was first introduced in our centre. 50 patients with uric acid stones were selected from 2 year groups, each with 25 patients and their urological managements were reviewed retrospectively. We concluded that DECT-KUB is an accurate wa
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Rodríguez-Plata, Irvin Tadeo, Martha Medina-Escobedo, Mario Basulto-Martínez, et al. "Implementation of a Technique Based on Hounsfield Units and Hounsfield Density to Determine Kidney Stone Composition." Tomography 7, no. 4 (2021): 606–13. http://dx.doi.org/10.3390/tomography7040051.

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Hounsfield units (HU) are a measure of radiodensity, related to the density of a tissue and the composition of kidney stones. Hounsfield density is what is related to the composition of kidney stones. In the standard acquisition method, these measures are arbitrary and dependent on the operator. This study describes the implementation of a technique based on the HU and Hounsfield density to predict the stone compositions of patients with nephrolithiasis. By conventional percutaneous nephrolithotomy, thirty kidney stone samples corresponding to the cortex, middle, and nucleus were obtained. The
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Kalabhavi, Srinivas, Pramod Makannavar, Revanasiddappa Kanagali, Prabhath A.N., and Narendrakumar Shah. "Dual Energy Computed Tomography (DECT) for Determination of Renal Calculi Composition - In-Vivo Analysis and In-Vitro Comparison with Qualitative Chemical Analysis - A Prospective Comparative Study at a Single Centre at SDM Medical College and Hospital – Dharwad, Karnataka." Journal of Evidence Based Medicine and Healthcare 8, no. 41 (2021): 3534–40. http://dx.doi.org/10.18410/jebmh/2021/641.

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BACKGROUND Dual energy computed tomography (DECT) is a new method of computed tomography (CT) imaging which allows to determine stone composition in addition to assessing stone morphology. The purpose of this study was to evaluate the role of dual energy CT (DECT) preoperatively to assess the composition of urinary stones and to compare it with post-operative in vitro qualitative chemical analysis as reference standard. METHODS Forty patients (18 male and 22 female) who presented with symptoms of renal stones in the department of urology were included in the study. All 40 patients who were dia
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Valente, Pedro, Hélder Castro, Inês Pereira, et al. "Urinary stone composition: Gender and age variations, and evolution in the last 7 years." Acta Urológica Portuguesa 34, no. 3-4 (2017): 7–12. http://dx.doi.org/10.24915/aup.34.3-4.17.

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Objectives: To evaluate urinary stone composition in our institution, its gender and age, including variations and the evolution in the last 7 years.&#x0D; Material and Methods: The authors reviewed all urinary stone analysis performed since January 2009 to September 2015 in our hospital – Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal. Patients were stratified by gender, age and stone composition analyzing the evolution of stone composition in different years. The stone analysis method was infrared spectroscopy.&#x0D; Results: From 302 valid stone analysis reports, 55,3% were female
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Saran, Rama Kishan, Pawan Katti, Kiran Mirdha, Sanya Saran, and Rajendra Prasad Takhar. "Spectrum of pediatric urinary stone composition in North Western India: analysis at tertiary care center." International Journal of Research in Medical Sciences 7, no. 11 (2019): 4102. http://dx.doi.org/10.18203/2320-6012.ijrms20194974.

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Background: Pediatric urolithiasis results in significant morbidity in later life. Incidence as well as site and chemical composition of calculi varies according to the changes in socio-economic conditions over time and the subsequent changes in dietary habits leading to a marked variation in the spectrum of urinary stone composition. To evaluate the spectrum of urinary stone composition in pediatric population from North-western India.Methods: This was a prospective observational study conducted between October 2013 and February 2019 which included pediatric patients with urolithiasis. Demogr
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32

Kolupayev, S. M., and E. P. Bereznyak. "Gender and Age Characteristics of the Mineral Composition of Urinary Stones in Patients with Urolithiasis." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5, no. 6 (2020): 124–28. http://dx.doi.org/10.26693/jmbs05.06.124.

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The paper presents the results of studying the features of the mineral composition of urinary stones obtained after spontaneous passage, as well as the use of minimally invasive surgical techniques. Material and methods. The study involved 61 patient with urolithiasis, depending who were examined depending on the sex and age of the patients. Infrared spectroscopy in the spectral range of 4000-400 cm-1 was used as a method for assessing the mineral composition of the stone. The next stage of the study consisted of analyzing the occurrence of stones of various mineral types in groups of patients
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33

Mehta, Tapan H., and David S. Goldfarb. "Uric Acid Stones and Hyperuricosuria." Advances in Chronic Kidney Disease 19, no. 6 (2012): 413–18. http://dx.doi.org/10.1053/j.ackd.2012.07.014.

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34

Warty, Yuni, Dewi Wulandari, and Eviyona Laurante Br Barus. "The Structure and Morphology of Uric Acid by Orthosiphon Aristatus." Jurnal Penelitian Pendidikan IPA 11, no. 3 (2025): 1147–52. https://doi.org/10.29303/jppipa.v11i3.6995.

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Urolithiasis is stone-like material that settles in the urinary tract. The materials that make up urinary stones are calcium oxalate, uric acid, cystine and stuvite. Several medical procedures are often applied to cure this disease. However, many patients choose traditional treatment by consuming herbal medicine. The aim of this research is to show the structure and morphology of uric acid with Orthosiphon Aristatus. This is very important to study as a basis for producing herbal medicines in nanometer sizes. Samples were prepared before characterization. Urid Acid and Orthosiphon aristatus sa
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35

Maddala, Sudarsana Rao, Bala Rambabu, Prabhakara Rao Medavankala, Jahangir Mohammad, and Shiva Prasad P. "A Clinical Study on Radiolucent(Uric Acid) Stones in Tertiary Care Center." International Journal of Pharmaceutical and Clinical Research 16, no. 2 (2024): 241–46. https://doi.org/10.5281/zenodo.11066276.

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<strong>Background:</strong>&nbsp;Uric acid, first recognized in 1776, is a component of bladder stones that is controlled by metabolism, kidney excretion, and synthesis. Acidic urine and metabolic syndrome are connected to an increased incidence of uric acid stones. The distribution of age and sex, predisposing factors, causal factors, and clinical presentation of uric acid urolithiasis are the main objectives of this study.&nbsp;<strong>Methods and Material:</strong>&nbsp;A clinical study on radiolucent stones was conducted at King George Hospital, Visakhapatnam, from July 2021 to July 2023.
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36

Kolupayev, S. M., N. M. Andonieva, O. M. Kirienko, V. V. Khanzhyn, and D. O. Iemets. "THE ROLE OF METABOLIC DISORDERS IN THE FORMATION OF UROLITHIASIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Problems of Endocrine Pathology 77, no. 3 (2021): 52–57. http://dx.doi.org/10.21856/j-pep.2021.3.07.

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The article presents the study of the influence of type 2 diabetes mellitus on the features of the urolithiasis development and factors affecting stone formation. As part of the study, 28 patients with type 2 diabetes mellitus were treated at the «Regional Medical Clinical Center of Urology and Nephrology named after V. I. Shapoval», where a comprehensive examination was carried out to determine the level of glycosylated hemoglobin, glomerular filtration rate, serum concentration of triglycerides, urea, creatinine and uric acid. All patients underwent ultrasound examination of the urinary syst
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37

Kolupayev, S. M., N. M. Andonieva, O. M. Kirienko, V. V. Khanzhyn, and D. O. Iemets. "THE ROLE OF METABOLIC DISORDERS IN THE FORMATION OF UROLITHIASIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Problems of Endocrine Pathology 77, no. 3 (2021): 52–57. http://dx.doi.org/10.21856/j-pep.2021.3.07.

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The article presents the study of the influence of type 2 diabetes mellitus on the features of the urolithiasis development and factors affecting stone formation. As part of the study, 28 patients with type 2 diabetes mellitus were treated at the «Regional Medical Clinical Center of Urology and Nephrology named after V. I. Shapoval», where a comprehensive examination was carried out to determine the level of glycosylated hemoglobin, glomerular filtration rate, serum concentration of triglycerides, urea, creatinine and uric acid. All patients underwent ultrasound examination of the urinary syst
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38

Welk, Blayne K., and Joel M. H. Teichman. "Uric acid nephrolithias in the era of noncontrast computed tomography." Canadian Urological Association Journal 2, no. 4 (2013): 420. http://dx.doi.org/10.5489/cuaj.844.

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We report 2 patients who presented with uric acid renal calculi. Both patients had previously been treated unsuccessfully for their stones with shock wave lithotripsy and were referred to our centre for percutaneous nephrolithomy. We were able to avoid surgery in both cases owing to the recognition of uric acid stone composition despite the calculi being visible on CT scout films.
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39

Presores, Janeth B., and Jennifer A. Swift. "Solution-mediated phase transformation of uric acid dihydrate." CrystEngComm 16, no. 31 (2014): 7278–84. http://dx.doi.org/10.1039/c4ce00574k.

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40

Subrat, Prasad, and Prasad Bharat. "An Analytical Attempt to Predict the Chemical Makeup of Urinary Calculi in Vivo Using CT Attenuation data." International Journal of Pharmaceutical and Clinical Research 15, no. 7 (2023): 1392–96. https://doi.org/10.5281/zenodo.11942455.

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<strong>Introduction:&nbsp;</strong>Chemically, there are many different kinds of stones, such as calcium stones, uric acid stones, struvite stones, and cystine stones, among others. There is a propensity for a certain type of stone to form in each pathologic category. Therefore, the care of the patient can and does depend on knowing the chemical makeup of the stone that the patient develops. determining whether the mean Hounsfield Unit (HU) value on computed tomography may be used to predict the chemical composition of urinary stones (CT).&nbsp;<strong>Method:&nbsp;</strong>This investigation
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41

Golovanov, S. A., M. Yu Prosyannikov, A. V. Sivkov, N. V. Anokhin, D. A. Voytko, and V. V. Drozhzheva. "Metabolic risk factors and urinary stones formation. VII: Uricosuria lithogenic features in men and women." Experimental and Сlinical Urology 16, no. 3 (2023): 154–64. http://dx.doi.org/10.29188/2222-8543-2023-16-3-154-164.

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Introduction. Hyperuricosuria usually considered as the main metabolic factor in the formation of uric acid stones, but this issue remains unclear. Gender differences in the prevalence of urolithiasis (UL) indicate the need for a more detailed study of the lithogenic properties of uricosuria and its role in the development of various metabolic types of UL. In this study, was investigated the effect of varying degrees of uricosuria in men and women with UL on metabolic parameters and the frequency of detection of urinary stones of different chemical composition. Materials and methods. A total o
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Djazuli, Palestin, Era H. M. Restijono, Retina Yunani, and Hana C. P. Wardhani. "Kadar BUN, Kreatinin, dan Morfologi Eritrosit pada Kura – Kura Sulcata (Geochelone sulcata) yang Terkena Bladder Stone." Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) 13, no. 2 (2023): 78–82. http://dx.doi.org/10.46549/jipvet.v13i2.325.

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Abstract This study aims to determine the levels of blood urea nitrogen (BUN), creatinine, and uric acid in sulcata turtles (Geochelone sulcata) affected by bladder stone. Sulcata turtles are one type of land turtle that are easily affected by bladder stones. Bladder stones that form in tortoises are composed of uric acid and minerals such as sodium, potassium and calcium. Formation of bladder stone in the urinary bladder of sulcata turtles can cause high levels of urea, creatinine, and erythrocyte morphology examination with whole blood samples taken from the jugular vein. Keywords: Bladder s
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43

Koirala, S. "Significance of analysing chemical composition of renal stones." Journal of Pathology of Nepal 4, no. 7 (2014): 560–64. http://dx.doi.org/10.3126/jpn.v4i7.10314.

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Background: This article aims to decipher chemical composition of renal stones and briefly outline laboratory tests and dietary habitual changes aimed at preventing stone recurrence. It is based on analysis of 95 renal stones received in a private lab in Kathmandu over a period of 1 year. Materials and Methods: Renal stones were analysed using simple qualitative biochemical tests.The stones were checked for presence of calcium, magnesium, ammonium, oxalate, phosphate, uric acid, cystine and carbonate. Results: Calcium was present in 97.8%, ammonium was present in 98.9%, phosphate was present i
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Asyana, Vepy, Leni Aziyus Fitri, Freddy Haryanto, Taufik Ridwan, and Nanda Fitri Ayu Muningrat. "Application of uCT-scan and infrared spectroscopy for determination of urinary stone components." Journal of Aceh Physics Society 10, no. 4 (2021): 88–93. http://dx.doi.org/10.24815/jacps.v10i4.19114.

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Abstrak. Batu kemih merupakan salah satu penyakit dengan tingkat prevalensi yang cukup tinggi di Indonesia. Pengetahuan komposisi pada kandungan batu kemih dapat membantu tenaga medis dalam melakukan justifikasi penanganan tindakan lanjut pada pasien dengan tepat.Tujuan penelitian iniadalah menentukan kandungan mineral yang terdapat pada batu kemih menggunakan metode analisa spektrum inframerah dan nilai hounsfield unit (HU) yang terdapat pada citra yang dihasilkan dari modality mCT-Scan. Hasil karakterisasi fourier transform infrared spectroscopy (FTIR) memperlihatkan kandungan mineral batu k
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Booz, Christian, Ibrahim Yel, Julian L. Wichmann, et al. "Diagnosis of Uric Acid-Based Urine Sedimentation in the Bladder Using Dual-Energy CT." Diagnostics 13, no. 3 (2023): 542. http://dx.doi.org/10.3390/diagnostics13030542.

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Urine sedimentation in the bladder can occur in various circumstances and can lead to urinary obstruction/stasis with associated pain. It is usually diagnosed with an ultrasound; however, CT is also used to assess the amount and to further check for urinary stones. Depending on the composition, urine sedimentation and stones can be treated medically by alkalinisation of the urine with potassium sodium hydrogen citrate in the case of uric acid-based sedimentation/stones. Due to technical developments and improved material differentiation and characterisation in CT imaging, dual-energy CT allows
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Yin, Kexin, Zhikang Yin, Zhenyu Liu, Junjie Yao, Yuzhou Wu, and Shuai Su. "Exploring the association between multiple factors and urolithiasis: A retrospective study and Mendelian randomization analysis." Medicine 103, no. 18 (2024): e37968. http://dx.doi.org/10.1097/md.0000000000037968.

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To investigate the relationship between several factors and urinary stone as well as different stone compositions. To guide the diagnosis, treatment, and prevention of urinary stone recurrence. We used bidirectional Mendelian randomization to analyze the causal relationship between hypertension and urinary stones, diabetes and urinary stones, and body mass index (BMI) and urinary stones. We retrospectively analyzed the medical records of patients with urinary stones admitted to a tertiary care hospital in Chongqing, China, from July 2015 to October 2022. Patients were included when they were f
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Vozianov, Oleksandr, and Andriy Sahalevych. "Current Opportunities of Litholytic Therapy in Multiple Bilateral Uric Acid Nephrolithiasis." Health of Man, no. 4 (December 27, 2024): 17–22. https://doi.org/10.30841/2786-7323.4.2024.322111.

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Uric acid urolithiasis accounts for approximately 10% of all urostone cases worldwide, with a higher risk in male patients, obesity (body mass index &gt; 30) and type 2 diabetes. Excessive intake of dietary acids combined with impaired buffering are risk factors that contribute to the formation of kidney stones in these patients. When the level of uric acid in the blood increases and the pH of urine decreases, an excess of uric acid occurs, which leads to the formation of urate stones. The American and European Urological Associations recommend oral alkalinizers such as potassium citrate or so
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48

Vozianov, Oleksandr, and Andriy Sahalevych. "Current Opportunities of Litholytic Therapy in Multiple Bilateral Uric Acid Nephrolithiasis." Health of Man, no. 4 (December 27, 2024): 17–22. https://doi.org/10.30841/2786-7323.4.2024.322111.

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Uric acid urolithiasis accounts for approximately 10% of all urostone cases worldwide, with a higher risk in male patients, obesity (body mass index &gt; 30) and type 2 diabetes. Excessive intake of dietary acids combined with impaired buffering are risk factors that contribute to the formation of kidney stones in these patients. When the level of uric acid in the blood increases and the pH of urine decreases, an excess of uric acid occurs, which leads to the formation of urate stones. The American and European Urological Associations recommend oral alkalinizers such as potassium citrate or so
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49

Haley, William E., El-Sayed H. Ibrahim, Mingliang Qu, Joseph G. Cernigliaro, David S. Goldfarb, and Cynthia H. McCollough. "The Clinical Impact of Accurate Cystine Calculi Characterization Using Dual-Energy Computed Tomography." Case Reports in Radiology 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/801021.

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Dual-energy computed tomography (DECT) has recently been suggested as the imaging modality of choice for kidney stones due to its ability to provide information on stone composition. Standard postprocessing of the dual-energy images accurately identifies uric acid stones, but not other types. Cystine stones can be identified from DECT images when analyzed with advanced postprocessing. This case report describes clinical implications of accurate diagnosis of cystine stones using DECT.
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Khan, Farah Aziz, Noura Al‐Jameil, Hajera Tabassum, Rana Hasanato, and Mohammad Fareed Khan. "Prevalence and Composition of Urinary Tract Stones from a Tertiary Care Hospital, Riyadh." South Asian Journal of Experimental Biology 2, no. 6 (2013): 247–51. http://dx.doi.org/10.38150/sajeb.2(6).p247-251.

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Urolithiasis is a common problem in elderly population of developed countries. Urinary stones formation is thought to be multifactorial because of climatic conditions, eating habits, luxurious lifestyle. A monocentric study was carried out to find the rate and chemical composition of calculi in Saudi Population of Riyadh. We studied total 332 urolithiasis patients of King Khalid University Hospital, of age ranging from 1‐90 years (255 M &amp; 77 F). Stone samples were obtained after surgery, for analysis. Fourier transform infrared spectroscopy determines the type and composition of each sto
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