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Dissertations / Theses on the topic 'Urine analysi'

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Published: 9 March 2023
Last updated: 31 July 2025

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1

PADOAN, ANDREA. "Statistical methods for mass spectrometry data analysis and identification of prostaste cancer biomarkers." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2014. http://hdl.handle.net/10281/50248.

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BACKGROUND Prostate Cancer (PCa) is the most common cancer among males in Europe. Patients developing early PCa sometimes refer non-specific symptoms, namely lower urinary tract symptoms (LUTS), and they usually undergo medical investigations based on Prostate Specific Antigen (PSA) and Digital Rectal Examination (DRE). Suspicious results of one or both testings are prerequisite to Prostate Biopsy. However, due to PSA low sensitivity/specificity in predicting positive prostate biopsy, the identification of new PCa biomarkers is actually a real need. MALDI-TOF/MS protein profiling could be a
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2

Rocha, Diogo Librandi da. "Desenvolvimento de procedimento analítico em fluxo com multicomutação para a determinação espectofotométrica de ácido úrico em urina." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/46/46133/tde-05102009-105307/.

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A mecanização de procedimentos analíticos em análises clínicas traz vantagens tais como minimização de erros sistemáticos e do tempo das análises. Sistemas de análises em fluxo com multicomutação apresentam grandes potencialidades nesse sentido, atendendo às necessidades da mecanização de procedimentos analíticos de maneira versátil e robusta. Estes sistemas permitem minimizar o consumo de reagentes e a geração de resíduos, devido ao gerenciamento preciso de pequenos volumes de soluções por dispositivos controlados eletronicamente, tais como microbombas solenoide. O fluxo pulsado proporcionado
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3

Lough, Patricia Schechter. "Use of urine samples for ethanol analysis." CSUSB ScholarWorks, 1989. https://scholarworks.lib.csusb.edu/etd-project/446.

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4

Paquin, Olivier. "La microalbuminurie chez le sujet âgé." Bordeaux 2, 1994. http://www.theses.fr/1994BOR2M113.

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5

Jansson, Emelie. "Gaskromatografisk metod för analys av GHB i urin." Thesis, Department of Physics, Chemistry and Biology, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-19651.

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<p>En metod för detektering och kvantifiering av <em>gamma</em>-hydroxysmörsyra (GHB) i urin med gaskromatografi (GC) är framtagen på Sahlgrenska universitetssjukhuset. Metoden är relativt unik då den inte kräver upparbetning i form av derivatisering, indunstning eller extraktion. Urinen surgörs med koncentrerad saltsyra och internstandard, <em>gamma</em>-valerolakton, tillsätts. GHB övergår då till laktonformen, <em>gamma</em>-butyrolakton (GBL). Därefter injiceras provet direkt på en GC-FID med en kapillärkolonn för glykoler och alkoholer. Detektion ner till 100 μmol/L är möjligt med en vari
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6

Cooper, Mark Thomas. "A chromatographic method for detecting phenolic metabolites of carbosulfan in urine." Thesis, Queensland University of Technology, 1989. https://eprints.qut.edu.au/35977/1/35977_Cooper_1989.pdf.

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The inability of the conventional blood cholinesterase test to reliably detect carbamate pesticide poisoning in humans prompted the investigation of an alternative surveillance method. Rapid, micro-scale sample treatment procedures were developed to extract the phenolic metabolites of carbosulfan from urine, convert these compounds to their dinitrophenyl ether derivatives and determine their concentrations quantitatively by nitrogen selective gas-liquid chromatography. This method was capable of detecting micro-gram levels of metabolites and performed to an accuracy of<+/ 10% and pre
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7

Chen, Hui-Chuen. "The urinary excretion of mercapturic acids in free-living adult males." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-12052009-020010/.

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8

Silva, Júnior Jarbas Miguel da. "Excreção urinária de derivados de purinas e de compostos nitrogenados de zebuínos em pastejo." Universidade Federal de Viçosa, 2014. http://locus.ufv.br/handle/123456789/5825.

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Made available in DSpace on 2015-03-26T13:55:26Z (GMT). No. of bitstreams: 1 texto completo.pdf: 876963 bytes, checksum: 2254ce6044753867875b6bfab3b2249e (MD5) Previous issue date: 2014-07-21<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study aimed evaluating the excretion of purine derivatives and nitrogen compounds in zebu cattle grazing, on different days and times within days. The experiment was conducted in the cattle department of the Federal University of Viçosa / MG, using five Nelore heifers with an average body weight of 300 ± 15 kg and 20 months of age, i
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9

Allen, Robert Douglas III. "Development of an assay for the detection of cytomegalovirus in urine." Thesis, Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/25410.

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10

Hoang, Tiffany Truc. "Speciation and identification of low molecular weight organoselenium metabolites in human urine." Diss., Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/30671.

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11

Abdelrazig, Salah M. A. "Mass spectrometry for high-throughput metabolomics analysis of urine." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/30600/.

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Direct electrospray ionisation-mass spectrometry (direct ESI-MS), by omitting the chromatographic step, has great potential for application as a high-throughput approach for untargeted urine metabolomics analysis compared to liquid chromatography-mass spectrometry (LC-MS). The rapid development and technical innovations revealed in the field of ambient ionisation MS such as nanoelectrospray ionisation (nanoESI) chip-based infusion and liquid extraction surface analysis mass spectrometry (LESA-MS) suggest that they might be suitable for high-throughput metabolomics analysis. In this thesis, LC-
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12

Bordin, Keliani. "Avaliação de biomarcadores da exposição humana à fumonisina B1 nos alimentos em municípios dos estados de São Paulo e Santa Catarina, Brasil." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/74/74132/tde-23042015-140349/.

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A fumonisina B1 (FB1) e uma micotoxina produzida pelo metabolismo secundário de espécies de Fusarium, principalmente F. verticillioides e F. proliferatum, os quais contaminam diversos alimentos antes e apos o processamento, sobretudo o milho e derivados, gerando graves problemas para a Saúde Pública e a qualidade dos alimentos. O objetivo deste trabalho foi avaliar a exposição humana a FB1 presente nos alimentos através da estimativa de ingestão da toxina na dieta e da análise de diferentes biomarcadores presentes em amostras de sangue, urina e cabelo. Além disso, foram investigados os efeitos
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13

Joensuu, Frida. "Behov av surgörning av urin vid analys för kalcium, fosfat och magnesium." Thesis, Örebro universitet, Institutionen för hälsovetenskaper, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-93001.

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Studier har tidigare visat surgörning urinprover inför analys av kalcium, fosfat och magnesium inte är nödvändigt. Dessa analyter är viktiga att analysera vid njursjukdomar och det görs med instrumentet Advia Chemistry XPT (Siemens AG, München, Tyskland) på Universitetssjukhuset Örebro. Syftet med arbetet var att se om samma resultat erhölls för kalcium, fosfat och magnesium beroende på om urinen var surgjord eller inte inför analys. Tre metoder utvärderades beträffande behov av surgörning av urin: Metod 1; den nuvarande metoden, urinen surgjordes till pH 3-4. Metod 2; utan surgörning, urinen
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14

West, Robert E. 1952. "Confirmation of urinary benzodiazepines by gas chromatography/mass spectrometry." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277228.

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A new method is described for the quantitative analysis of urinary benzodiazepines by gas chromatography/mass spectrometry. Development work was aimed at satisfying federal requirements for methods used in forensic urine drug testing which have become the standard in the laboratory industry. Trimethylsilyl (TMS), tert-butyl-dimethylsilyl (TBDMS) and benzophenone derivatives were tested in the development of the new assay. TBDMS derivatives were found to be the most suitable for the analysis of six common benzodiazepine metabolites. Precision for all metabolites tested, as measured by the withi
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15

Couchman, Lewis. "LC-MS/MS analysis of buprenorphine and norbuprenorphine in urine." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511397.

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16

Hassan, Syed Saeed-Ul. "Rapid immunological methods for analysis of dexamethasone in equine urine." Thesis, University of Sunderland, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245822.

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17

Kirk, Jayne Marie. "Mass Spectrometric Analysis of Steroid Hormones for Application in Analysis of Bovine Urine." Thesis, University of York, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485830.

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Analytical strategies for the identification and quantification of up to 14 androgenic steroids and up to 17 corticosteroids have been evaluated and applied to bovine urine. The two classes ofsteroid have been analysed both as the native species and as Girard P hydrazone derivatives. Triple quadrupole mass spectrometry, operated in multiple reaction monitoring mode, has permitted the development of methods that enable the simultaneous detection of a range ofandrogenic steroids and corticosteroids at the ng mL-1 level. For a non-targeted approach, screening for the presence of corticosteroids w
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18

Stubbs, Christopher. "High performance liquid chromatographic analysis of erythromycin in serum and urine." Thesis, Rhodes University, 1985. http://hdl.handle.net/10962/d1004581.

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Erythromycin, a macrolide antibiotic used mainly against gram-positive bacteria has been in clinical use since 1952 (1). Previous pharmacokinetic data published on this antibiotic have been derived predominantly from microbiological assay techniques. However, these techniques are relatively imprecise as well as being non-specific and extremely tedious to perform. A novel high performance liquid chromatographic analysis of erythromycin in human serum and urine using U.V. detection at 200 nm and/or electrochemical detection using both an amperometric and a coulometric electrochemical detector is
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19

Kelly, Barbara M. "The analysis of biological fluids for acylcarnitines." Thesis, Open University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326566.

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20

Dumitrescu, Vlad Andrei. "Comparative analysis of biogas slurry and urine as sustainable nutrient sources for hydroponic vertical farming." Thesis, Linköpings universitet, Tema vatten i natur och samhälle, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-96368.

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Sustainable alternatives to using mined nutrients in agriculture must be found in order to limit environmental impacts such as eutrophication, habitat destruction and greenhouse gas emis-sions. Biogas slurry and urine recycled to hydroponic food production (a type of soilless agri-culture) have the potential of providing inorganic nitrogen and phosphorus, the main essential nutrients required for plant growth. A Life Cycle Inventory Assessment (LCI) methodology has been used to compare the systems of producing artificial fertilizer, biogas slurry and urine based nutrient solutions for the grow
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21

Hannon, Sarrah. "Analysis of cocaine adulterants and their metabolites in real patient urine samples." Thesis, Boston University, 2013. https://hdl.handle.net/2144/12114.

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Thesis (M.S.)--Boston University<br>Cocaine is one of the most common drugs of abuse in the United States today, but street-quality cocaine is decreasing in purity each year. This change in purity requires a shift in the focus of cocaine analysis in forensic laboratories. In recent years, many federal agencies have begun testing and profiling for the adulterants and diluents present in cocaine samples submitted as evidence. By analyzing the compounds present in the street-quality samples, forensic chemists may be able to track the cocaine back to its source, based on the unique identities of c
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22

Wu, Ruige, and 吴瑞阁. "Microchip-capillary electrophoresis with two-dimensional separation and isotachophoresis preconcentration for determining low abundanceproteins in human urine and dairy products." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46506044.

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23

FERREIRA, Pablo Gomes. "Avaliação do efeito da membrana de látex de Hevea brasiliensis no reparo de defeito da parede abdominal de rato." Universidade Federal de Alfenas, 2007. https://bdtd.unifal-mg.edu.br:8443/handle/tede/752.

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A hérnia incisional (HI) é uma das complicações tardias das laparotomias, podendo acometer até 20% dos pacientes operados. A utilização de próteses representou um avanço sem precedentes no reparo da HI. Contudo, não há ainda tratamento ideal para o reparo e prevenção desse mal. A membrana de látex da seringueira demonstrou atividade cicatrizante e angiogênica em estudos in vitro e in vivo. Assim, o objetivo deste trabalho foi avaliar o efeito da membrana de látex sobre o reparo da parede abdominal lesada de ratos. Foram utilizados ratos machos Wistar com peso de 340 ± 20 g, nos quais foi
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24

De, Kock Neil. "The development of direct infusion mass spectrometry method for analysis of small metabolites in urine." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/80213.

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Thesis (MSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: This study focused on the development of an analytical method whereby creatinine, creatine and caffeine could be determined quantitatively. Urine is the preferred body fluid for the analysis of metabolites that the body excretes after administration of medicinal and illicit drugs. The detection of these metabolites depends on the volume of water the patient has drunk or, in criminal cases, the amount of water the suspect may deliberately add to their urine to dilute it. Creatinine, whose concentration in urine has been found to
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Low, Ann Stewart. "An evaluation of analytical procedures for detection of drug abuse with particular reference to opiates." Thesis, Robert Gordon University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242985.

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26

Kim, Yuni T. "The effects of broccoli on the excretion of urinary conjugates." Diss., Virginia Tech, 1992. http://hdl.handle.net/10919/38535.

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The effects of dietary broccoli on the body's ability to detoxify were studied in 18 male subjects between the ages of 22-40 years. The biological parameters used for measuring detoxification were the four major urinary conjugates, namely, mercapturates, sulfoconjugates, glucuronides, and amino acid conjugates. Dietary broccoli increased the urinary excretion of mercapturates and sulfoconjugates, but did not influence the excretion of glucuronides and amino acid conjugates. A significant linear trend was observed over the six-day broccoli diet treatment for both urinary mercapturate (P<0.005)
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27

Sena, Laís Cristina Santana. "Desenvolvimento de método analítico para determinação dos principais adulterantes da cocaína em urina humana." Universidade Federal de Sergipe, 2016. https://ri.ufs.br/handle/riufs/3944.

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Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq<br>Cocaine is a stimulant that features a strong ability to cause dependence. Often adulterants are added to this drug in order to mimic its action or minimize its adverse effects. When there are other pharmacologically active components in the drug composition, severe problems can occur to users’ health, such as intoxication symptoms. Thus, the aim of this study was to develop a method for the determination of the main adulterants of cocaine (caffeine, levamisole, lidocaine, phenacetin, diltiazem, and hydroxyzine)
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28

Corrêa, Cristiana Leslie. "Validação da urina para análise toxicológica de etanol em \"Programas de Controle e Prevenção do uso de álcool e drogas no local de trabalho\"." Universidade de São Paulo, 1997. http://www.teses.usp.br/teses/disponiveis/9/9137/tde-24112015-182937/.

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Nos dias atuais tem havido uma crescente preocupação com o consumo de álcool, bem como de outras drogas de abuso, no local de trabalho. Com isso, começaram a ser implantados programas que visam o controle e a prevenção do uso de álcool e drogas neste ambiente. De um modo geral, esses programas utilizam a urina dos trabalhadores para a realização de análises toxicológicas. O presente trabalho procurou validar a urina como amostra para determinação do etanol, através da (1) padronização de um método de análise e (2) estudo das correlações entre concentrações sanguínea, urinária e no ar exalado,
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29

Barbosa, Analívia Martins. "Período de coleta de urina e de fezes para avaliação da excreção de creatinina, produção microbiana e digestibilidade aparente dos nutrientes em Nelore." Universidade Federal de Viçosa, 2005. http://locus.ufv.br/handle/123456789/5002.

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Made available in DSpace on 2015-03-26T13:46:45Z (GMT). No. of bitstreams: 1 texto completo.pdf: 246842 bytes, checksum: f7b7371c8cb299837b636e055567a1b8 (MD5) Previous issue date: 2005-03-02<br>This trial was carried out to evaluate the effect of periods of urine and feces collection on urinary excretion of creatinine, urea and purine derivatives, absorbed purine, microbial nitrogen compounds production (Nmic), apparent digestibility of dry matter (DM), organic matter (OM), crude protein (CP), ether extract (EE), neutral detergent fiber (NDF) and nonfiber carbohydrates (CNF) and total diges
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30

Hassen, Imed Eddine. "Analyse de traces et ultratraces (organiques et inorganiques) dans les matrices biologiques." Lyon 1, 2004. http://www.theses.fr/2004LYO10126.

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La majorité des analyses biologiques s'appuient sur les deux matrices urine et sang, qui présentent un inconvénient majeur au niveau de la fenêtre de détection très courte. Cette limitation a contribué ces dernières années à l'essor d'une matrice alternative : les cheveux, support beaucoup plus stable. L'objectif de ce travail est de comparer les résultats d'analyse de xénobiotiques dans l'urine et les cheveux. L'application principale porte sur l'étude le phénomène du tabagisme, examiné sous l'angle du traitement de la dépendance. Un suivi d'un programme de sevrage a été effectué par CG-SM et
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Diaz, Sílvia de Oliveira. "Pregnancy and newborns disorders followed by urine metabolomics." Doctoral thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13110.

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Doutoramento em Química<br>Chapter 1 introduces the scope of the work by identifying the clinically relevant prenatal disorders and presently available diagnostic methods. The methodology followed in this work is presented, along with a brief account of the principles of the analytical and statistical tools employed. A thorough description of the state of the art of metabolomics in prenatal research concludes the chapter, highlighting the merit of this novel strategy to identify robust disease biomarkers. The scarce use of maternal and newborn urine in previous reports enlightens the relevance
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Colombeli, Adriana Scotti da Silva. "Avaliação do potencial de interferência analítica de fármacos na análise química do exame de urina." Florianópolis, SC, 2006. http://repositorio.ufsc.br/xmlui/handle/123456789/88952.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.<br>Made available in DSpace on 2012-10-22T15:16:05Z (GMT). No. of bitstreams: 1 233101.pdf: 855282 bytes, checksum: 0cc76a508ef9aa577987b2e41271fece (MD5)<br>O exame de urina proporciona informações sobre patologias renais e do trato urinário, bem como sobre algumas moléstias extra-renais. Pela sua simplicidade, baixo custo e facilidade na obtenção da amostra para análise, é considerado exame de rotina. Fármacos podem alterar exames laboratoriais por meio de meca
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33

Pujos, Estelle. "Analyse de traces dans les matrices urinaires : application au contrôle antidopage." Lyon 1, 2004. http://www.theses.fr/2004LYO10120.

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Les progrès pharmaceutiques et les enjeux croissants des résultats sportifs ont permis le développement du dopage. Devenant un problème de santé publique, les organisations établissent des listes d'interdictions et développent des contrôles nécessitant des méhtodes d'analyses fiables. La première partie de ce travail concerne la mise au point de la détection de neuf métabolites de stéroi͏̈des dans l'urine, en vue d'analyses par spectrométrie de masse isotopique. Cette étude nous a permis de développer une analyse globale concernant le sulfate de DHEA, les corticostéroi͏̈des et les androgènes d
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Fong, Ka-wah Martin, and 方家華. "Adaptation of a simplified method for urinary iodine for studying the iodine status of local Chinese." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31971726.

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Thomas, Marie Martineau Guy-Pierre. "Prévalence de infections urinaires chez la truie gestante (ITU) selon le stade de gestation et la parité dans deux contextes d'abreuvement différents." [S.l.] : [s.n.], 2007. http://oatao.univ-toulouse.fr/1754/1/debouch_1753.pdf.

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Silva, Adriana Scotti da. "Avaliação da interferência analítica de fármacos na determinação de proteínas e cetonas no exame químico de urina." Florianópolis, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/100495.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.<br>Made available in DSpace on 2013-06-25T19:43:19Z (GMT). No. of bitstreams: 1 310058.pdf: 1105263 bytes, checksum: af4972ecbcb412b86bd83dc70f8dc500 (MD5)<br>Interferências de fármacos em análises laboratoriais podem levar a resultados incorretos, diagnósticos equivocados e procedimentos desnecessários. O exame de urina permite a detecção de processos patológicos intrínsecos e extrínsecos ao sistema urinário, e é importante, sobretudo para diabéticos e pacientes
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BELLINTANI, SANDRA A. "Estudo de uma metodologia dosimetrica para plutonio por meio de analise radiotoxicologica em urina." reponame:Repositório Institucional do IPEN, 1988. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9893.

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Made available in DSpace on 2014-10-09T12:32:32Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:08:58Z (GMT). No. of bitstreams: 1 03261.pdf: 2839312 bytes, checksum: fc6899707bcade3ddd16f989bb548c04 (MD5)<br>Dissertacao (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP
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Shreeram, Devesh Dadhich. "Electrochemical Analysis of Genetically Engineered Bacterial Strains in a Urine-Based Microbial Fuel Cell." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1458814734.

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39

SANTORELLI, LUCIA. "Proteomic analysis of urine-based liquid biopsy to provide new insights into renal diseases." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2020. http://hdl.handle.net/10281/263397.

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L'area di indagine delle paotlogie renali è un campo ampio e complesso e molte delle cause che sono alla loro base non sono completamente comprensibili o curabili. A tal motivo, oltre ad una migliore comprensione della loro eziopatogenesi, è necessario individuare in maniera precisa i fattori di rischio, al fine di migliorare la prognosi e personalizzare il trattamento terapico. Lo sviluppo e l’implementazione di nuovi approcci, come l'analisi proteomica basata sulle urine, come biopsia liquida è attualmente una delle scelte più giuste da compiere. Infatti, l'uso dell'analisi proteomica per la
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Rocha, Diogo Librandi da. "Desenvolvimento de procedimentos analíticos em fluxo com multicomutação e foto-oxidação em linha para determinação espectrofotométrica de espécies de interesse ambiental, alimentício e clínico." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-06082013-075926/.

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A mecanização do preparo de amostras minimiza erros sistemáticos, a geração de efluentes e o tempo de análise. Sistemas em fluxo com microbombas solenoide (MPFS) atendem aos requisitos da mecanização de maneira robusta e versátil. Sendo assim, foram desenvolvidos procedimentos analíticos baseados em MPFS e foto-oxidação em linha visando ao fracionamento de fósforo em extratos de alimentos e águas naturais e à determinação de cloreto em águas naturais e urina. Fósforo é um nutriente importante cuja biodisponibilidade depende de sua forma química, tornando importante o fracionamento. O monitoram
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41

Scalabre, Aurélien. "Étude clinique des modifications du profil métabolique urinaire secondaires à une anomalie congénitale de l’écoulement des urines par Résonance Magnétique Nucléaire et analyse métabolomique." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSE1272/document.

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Les dilatations des voies urinaires de diagnostic anténatal (DVU) peuvent être transitoires, ou correspondre à une anomalie significative de l'écoulement des urines pouvant entrainer une dégradation de la fonction rénale. L'identification de biomarqueurs urinaires pourrait contribuer à différencier précocement les uropathies des dilatations transitoires. La métabolomique permet l'identification de toutes les molécules de bas poids moléculaire présentes dans un échantillon biologique et la mise en évidence d'une signature métabolique associée à un événement physiopathologique. L'objectif princi
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42

Li, Xin. "Comparative evaluation of the extraction and analysis of urinary phospholipids and lysophospholipids using MALDI-TOF/MS." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/265182.

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京都大学<br>新制・課程博士<br>博士(医学)<br>甲第23410号<br>医博第4755号<br>新制||医||1052(附属図書館)<br>京都大学大学院医学研究科医学専攻<br>(主査)教授 村川 泰裕, 教授 長尾 美紀, 教授 柳田 素子<br>学位規則第4条第1項該当<br>Doctor of Medical Science<br>Kyoto University<br>DFAM
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43

Van, Buynder Paul G. "The epidemiology of renal disease in Aboriginal Australians." Thesis, The University of Sydney, 1991. https://hdl.handle.net/2123/26311.

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Data from dialysis units in the Northern Territory and, from a rural community screening program in South Australia, suggested there was a high prevalence of renal disease in Aboriginal Australians. This thesis documents the high prevalence of urinary abnormalities in three Aboriginal communities in the Northern Territory and examines factors of aetiological relevance. After ethical approval from the local institutional ethics committee which has Aboriginal representation, a randomly chosen group of 327 adults and 180 children consented to participate in pilot studies in three communitie
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44

Yap, Bin Kiat. "Exercise-stress responses of urinary hormones." Thesis, The University of Sydney, 1994. https://hdl.handle.net/2123/26858.

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Knowledge on the effects of episodic or short-term exercise-stress on changes of corticosteroids, androgenic steroids and gonadotropins still remains fragmentary and inconclusive. In this study an alternative approach to investigate these changes, based on the concentration ratios of urinary total testosterone (T), luteinizing hormone (LH), free cortisol(F),cortisone (E) and their primary metabolites tetrahydrocortisol (THF) and tetrahydrocortisone (THE), was developed to profile shortterm exercise-stress responses in healthy, drug-free male athletes and sedentary subjects. The hormonal con
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45

Batista, Carla Alice Theodoro. "Desenvolvimento de um sensor eletroquímico para análise de lactato em amostras de urina e saliva." Universidade Federal de Juiz de Fora, 2012. https://repositorio.ufjf.br/jspui/handle/ufjf/1532.

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Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-06-28T12:37:36Z No. of bitstreams: 1 carlaalicetheodorobatista.pdf: 1563638 bytes, checksum: 1ab6a3b656a9e8afc9dccb7d96235060 (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-06-28T12:51:20Z (GMT) No. of bitstreams: 1 carlaalicetheodorobatista.pdf: 1563638 bytes, checksum: 1ab6a3b656a9e8afc9dccb7d96235060 (MD5)<br>Made available in DSpace on 2016-06-28T12:51:20Z (GMT). No. of bitstreams: 1 carlaalicetheodorobatista.pdf: 1563638 bytes, checksum: 1ab6a3b656a9e8afc9dccb7d96235060 (MD5)
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46

Troster, Charles Micah Smolkin. "Trace analysis of cyclophosphamide and its metabolites in urine by liquid chromatography-tandem mass spectrometry." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/29263.

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Cyclophosphamide (CP) is an antineoplastic drug used to treat a wide variety of cancers and immune disorders. CP is also a highly toxic alkylating agent, classified as an IARC Group 1 carcinogen. Workers in health-care environments are vulnerable to occupational exposure to CP, primarily via inhalation and dermal absorption. CP is a prodrug; both its therapeutic effectiveness and toxicity are activated through metabolism. To date, however, no study measuring occupational exposure to CP has successfully analyzed its metabolites. The main objective of this work was to develop an analytical metho
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47

Cromwell, Wyn Zhang. "An Analysis of the Loops of Henle and Urine Concentrating Mechanisms in the Kangaroo Rat." Thesis, The University of Arizona, 2011. http://hdl.handle.net/10150/144330.

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48

Lugogo, Rita de Nicolo. "Quantitative assessment of daily urinary conjugates in an adult male population." Diss., This resource online, 1992. http://scholar.lib.vt.edu/theses/available/etd-06062008-171211/.

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49

Avery, Thomas W. "Further characterization of the direct injection nebulizer for flow injection analysis and liquid chromatography with inductively coupled plasma spectrometric detection." Virtual Press, 1988. http://liblink.bsu.edu/uhtbin/catkey/539620.

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A direct injection nebulizer (DIN) was constructed in our laboratory and was evaluated as an interface between a liquid chromatography column and an inductively coupled plasma-atomic emission spectrometer (ICP-AES). Optimum operating conditions, detection limits and reproducibility of the DIN closely matched literature data for a somewhat different commercial device. In addition, when using the DIN for sample introduction, the ICP detection exhibited uniform response towards phosphorous compounds of different volatilities.<br>Department of Chemistry
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50

Prado, Isabelle. "L'examen bactériologique des urines a-t-il encore quelque intérêt ?" Caen, 1991. http://www.theses.fr/1991CAEN3039.

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