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1

Örd, Lenna, Toomas Marandi, Marit Märk, et al. "Evaluation of DOAC Dipstick Test for Detecting Direct Oral Anticoagulants in Urine Compared with a Clinically Relevant Plasma Threshold Concentration." Clinical and Applied Thrombosis/Hemostasis 28 (January 2022): 107602962210843. http://dx.doi.org/10.1177/10760296221084307.

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Measuring direct oral anticoagulant (DOAC) concentrations might be necessary in certain clinical situations but is not routinely performed. The DOAC Dipstick is a new rapid test for detecting DOACs in urine. The aim of this study was to evaluate the possible uses and limitations of the DOAC Dipstick and to compare visual analysis and DOASENSE Reader analysis of DOAC Dipstick pads. Plasma and urine samples were collected from 23 patients taking DOACs. DOAC concentrations in plasma and urine were measured by chromogenic substrate assays and in urine also by the DOAC Dipstick. Plasma concentratio
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2

Clark, D. R., and T. M. Hajar. "Detection and confirmation of cocaine use by chromatographic analysis for methylecgonine in urine." Clinical Chemistry 33, no. 1 (1987): 118–19. http://dx.doi.org/10.1093/clinchem/33.1.118.

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Abstract Methylecgonine is a common metabolite of cocaine in man. We prepared methylecgonine and developed thin-layer chromatographic and gas-chromatographic methods for its detection in urine. Seventy urine specimens from our drug screening laboratory were tested by our method and by EMIT. Both methods were positive for 26 urines, and both were negative for 42 urines. The other two urines were shown to contain cocaine by GC/MS, and no detectable metabolites. We thus demonstrated that detection of methylecgonine and cocaine is as sensitive a test for cocaine use as EMIT.
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3

van Kuilenburg, André B. P., Henk van Lenthe, Monika Löffler, and Albert H. van Gennip. "Analysis of Pyrimidine Synthesis “de Novo” Intermediates in Urine and Dried Urine Filter- Paper Strips with HPLC–Electrospray Tandem Mass Spectrometry." Clinical Chemistry 50, no. 11 (2004): 2117–24. http://dx.doi.org/10.1373/clinchem.2004.038869.

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Abstract Background: The concentrations of the pyrimidine “de novo” metabolites and their degradation products in urine are useful indicators for the diagnosis of an inborn error of the pyrimidine de novo pathway or a urea-cycle defect. Until now, no procedure was available that allowed the analysis of all of these metabolites in a single analytical run. We describe a rapid, specific method to measure these metabolites by HPLC–tandem mass spectrometry. Methods: Urine or urine-soaked filter-paper strips were used to measure N-carbamyl-aspartate, dihydroorotate, orotate, orotidine, uridine, and
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4

Regeniter, Axel, André Scholer, and Werner H. Siede. "Die quantitative Analyse von Markerproteinen im Urin Quantitative analysis of marker proteins in urine." LaboratoriumsMedizin 29, no. 5 (2005): 309–16. http://dx.doi.org/10.1515/jlm.2005.042.

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5

Starcher, Barry, and Marti Scott. "Fractionation of Urine to Allow Desmosine Analysis by Radioimmunoassay." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 29, no. 1 (1992): 72–78. http://dx.doi.org/10.1177/000456329202900111.

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The present study was designed to re-evaluate the radioimmunoassay for desmosine in urine, which is currently used as a measure of elastin metabolism. Using ion exchange chromatography, gel filtration and affinity chromatography it was shown that at least five other compounds in hydrolysates of human urine competed for desmosine in the RIA. Fractionating the urine prior to hydrolysis with acetone removed one of the major contaminants. The other contaminants could subsequently be removed by extracting the urine hydrolysate with a mixture of chloroform/ethanol (60:40). Samples from nine normal a
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6

Peelen, G. O., J. G. de Jong, and R. A. Wevers. "HPLC analysis of oligosaccharides in urine from oligosaccharidosis patients." Clinical Chemistry 40, no. 6 (1994): 914–21. http://dx.doi.org/10.1093/clinchem/40.6.914.

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Abstract Analysis of urinary oligosaccharides by thin-layer chromatography (TLC) is used as screening procedure for 10 different lysosomal diseases. We tested the usefulness of HPLC in screening, using a CarboPac PA1 column (Dionex), pulsed amperometric detection (PAD), and post-column derivatization (PCD). Patterns from six types of oligosaccharidoses were compared with normal urinary patterns and with the TLC patterns. PAD appeared to be nonspecific and therefore is applicable only to desalted urine samples. PCD was more specific and applicable to nondesalted urine samples, albeit with a low
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7

WU, Jun, Chao Yan ZHOU, Ming Keong WONG, Hian Kee LEE, Hua CHI, and Choon Nan ONG. "Speciation of Aluminum in Urine." Analytical Sciences 12, no. 4 (1996): 641–45. http://dx.doi.org/10.2116/analsci.12.641.

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8

Nowrousian, M. R., D. Brandhorst, C. Sammet, et al. "Relationship between Serum Concentrations and Urinary Excretions of Monoclonal Free Light Chains (mFLC) Detectable as Bence Jones Proteins (BJP) by Immunofixation Electrophoresis (IFE) in Patients with Multiple Myeloma (MM)." Blood 106, no. 11 (2005): 5060. http://dx.doi.org/10.1182/blood.v106.11.5060.5060.

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Abstract Introduction. mFLC are important markers for the diagnosis and monitoring of MM. This study for the first time determines serum concentrations of mFLC which are required to produce renal overflow and BJP in urine detectable by IFE and evaluates the relationship between urinary excretions of mFLC and renal function. Patients and methods. 378 paired samples of serum and 24-h-urine from 82 patients were evaluated during the course of their disease. Serum FLC concentrations were measured nephelometrically using an automated immunoassay. Urine samples were tested for clonal bands using aga
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9

Degen, Gisela H., Jörg Reinders, Martin Kraft, et al. "Citrinin Exposure in Germany: Urine Biomarker Analysis in Children and Adults." Toxins 15, no. 1 (2022): 26. http://dx.doi.org/10.3390/toxins15010026.

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Citrinin (CIT), a mycotoxin known to exert nephrotoxicity, is a contaminant in food and feed. Since CIT contamination is not regularly analyzed, data on its occurrence and especially levels in food commodities are insufficient for conducting a conventional exposure assessment. Yet, human biomonitoring, i.e., an analysis of CIT and its metabolite dihydrocitrinone (DH-CIT) in urine samples allows to estimate exposure. This study investigated CIT exposure in young (2–14 years) and adult (24–61 years) residents of three federal states in Germany. A total of 179 urine samples from children and 142
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10

Harnly, James, Craig Charron, David Baer, and Janet Novotny. "Elimination of the Variance Between Individuals Is Necessary to Evaluate the Impact of Garlic on the Metabolic Profile of Human Urine." Current Developments in Nutrition 4, Supplement_2 (2020): 402. http://dx.doi.org/10.1093/cdn/nzaa045_035.

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Abstract Objectives To determine the impact of garlic on the metabolic profile of urine. Methods On the first day 17 fasting subjects were fed a breakfast of bread and butter. Urines were collected before and 3 hours after the meal. On a second day, the same 17 fasting subjects were fed a meal of bread, butter, and garlic. Urines were again collected before and 3 hours after the meal. Samples were analyzed by metabolomics using liquid chromatography-mass spectrometry (LC-MS) and data were subjected to analysis of variance-principal component analysis (ANOVA-PCA). Results 637 compounds were fou
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11

Young, David C., Sandra Craft, Mary-Clare Day, Barbara Davis, Elizabeth Hartwell, and Song Tong. "Comparison of Abbott LCxChlamydia trachomatisAssay With Gen-Probe PACE2 and Culture." Infectious Diseases in Obstetrics and Gynecology 8, no. 2 (2000): 112–15. http://dx.doi.org/10.1155/s1064744900000119.

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In this study the LCx assay (a nucleic acid amplification assay) forChlamydia trachomatisin endocervical samples was compared with the Gen-Probe PACE2 assay (a nucleic acid probe assay) for endocervical samples, and with endocervical culture. In addition, the efficacy of the LCx assay was determined for midstream clean-catch urine samples because it is often necessary to obtain such a sample for routine urine culture and it is simpler to collect only a single sample without also collecting a first-void urine for LCx. Endocervical specimens from 205 patients were tested forC. trachomatisvia LCx
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12

Hamid Saad Mohmoud1, Marai. "Dipstick urine analysis screening among asymptomatic dogs of k9 units." Iraqi Journal of Veterinary Medicine 42, no. 1 (2018): 61–64. http://dx.doi.org/10.30539/011.

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13

Blijdorp, Charles J., Omar A. Z. Tutakhel, Thomas A. Hartjes, et al. "Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles." Journal of the American Society of Nephrology 32, no. 5 (2021): 1210–26. http://dx.doi.org/10.1681/asn.2020081142.

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BackgroundUrinary extracellular vesicles (uEVs) are a promising source for biomarker discovery, but optimal approaches for normalization, quantification, and characterization in spot urines are unclear.MethodsUrine samples were analyzed in a water-loading study, from healthy subjects and patients with kidney disease. Urine particles were quantified in whole urine using nanoparticle tracking analysis (NTA), time-resolved fluorescence immunoassay (TR-FIA), and EVQuant, a novel method quantifying particles via gel immobilization.ResultsUrine particle and creatinine concentrations were highly corr
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Al Ayoubi, Manar, Mohammad Salman, Lucia Gambacorta, Nada El Darra, and Michele Solfrizzo. "Assessment of Dietary Exposure to Ochratoxin A in Lebanese Students and Its Urinary Biomarker Analysis." Toxins 13, no. 11 (2021): 795. http://dx.doi.org/10.3390/toxins13110795.

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The present study investigated the dietary and urinary OTA occurrence among 44 Lebanese children. Relying on HPLC-FLD analysis, OTA was found in all the urine samples and in 46.5% and 25% of the 24 h duplicate diet and dinner samples, respectively. The means of OTA levels in positive samples were 0.32 ± 0.1 ng/g in 24 h diet, 0.32 ± 0.18 ng/g in dinner and 0.022 ± 0.012 ng/mL in urines. These values corresponded to margin of exposure (MOE) means of 7907 ± 5922 (neoplastic) and 2579 ± 1932 (non-neoplastic) calculated from positive 24 h diet, while 961 ± 599 (neoplastic) and 313 ± 195 (non-neopl
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15

SERA, K., Y. MIURA, and S. FUTATSUGAWA. "APPLICATION OF A STANDARD-FREE METHOD TO QUANTITATIVE ANALYSIS OF URINE SAMPLES." International Journal of PIXE 11, no. 03n04 (2001): 149–58. http://dx.doi.org/10.1142/s0129083501000207.

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A standard-free method of quantitative analysis, which is based on the fact that the total yield of continuous x-rays from the sample approximately corresponds to effective weight of the sample, was developed and has been applied to some typical bio-samples such as serum, whole blood, hair and untreated bone. In this work, the standard-free method was applied to untreated urine samples. This method allows us to perform sample preparation only by dropping 5 μl of urine sample onto a backing film. It requires neither a large amount of urine nor the internal standard. As the results, values of co
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16

Sánchez-Carbayo, Marta, Antonia Espasa, Virtudes Chinchilla, et al. "New Electrochemiluminescent Immunoassay for the Determination of CYFRA 21-1: Analytical Evaluation and Clinical Diagnostic Performance in Urine Samples of Patients with Bladder Cancer." Clinical Chemistry 45, no. 11 (1999): 1944–53. http://dx.doi.org/10.1093/clinchem/45.11.1944.

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Abstract Background: A new electrochemiluminescent immunoassay (ECLIA) has been developed for the determination of cytokeratin 19 (CYFRA 21-1) in the Elecsys 2010 immunoassay system. Urinary CYFRA 21-1 might have a role in the diagnosis of bladder cancer. Methods: We performed an analytical evaluation of the CYFRA 21-1 ECLIA for serum and urine samples. The clinical value of urinary CYFRA 21-1 for the detection of bladder cancer was evaluated through its measurement in 226 urine samples from symptomatic and asymptomatic controls. Results: At concentrations of 2–30 μg/L, within-assay imprecisio
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17

Zhao, Hongda, Ryan Tsz-Hei Tse, Carol Ka-Lo Cheng, et al. "In vitro cytotoxicity of human urine and its potential toxic parameters towards bladder cancer cells." PLOS ONE 17, no. 10 (2022): e0276127. http://dx.doi.org/10.1371/journal.pone.0276127.

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Background Bladder cancer (CaB) has a high recurrence rate despite surgery. As bladder is constantly filled with urine, it is worthwhile to investigate whether it could have any detrimental effects on bladder cancer cells. Methods We investigated the cytotoxicity of urine samples from CaB patients and normal controls on four CaB cell lines and tested the percentage of cell death, proliferation, adhesion, invasion and colonies formation ability. In order to identify the potential components involving in urine cytotoxicity, we evaluated some basic physiochemical parameters of urines, such as pH,
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18

Gaspari, Valeria, Camilla Ceccarani, Marco Severgnini, et al. "First-Void Urine Microbiome in Women with Chlamydia trachomatis Infection." International Journal of Molecular Sciences 23, no. 10 (2022): 5625. http://dx.doi.org/10.3390/ijms23105625.

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Background: Chlamydia trachomatis (CT) is the agent of the most common bacterial sexually transmitted infection worldwide. Until now, little information is available about the microbial composition of urine samples during CT urethritis. Therefore, in this study, we characterized the microbiome and metabolome profiles of first-void urines in a cohort of women with CT urethral infection attending an STI clinic. Methods: Based on CT positivity by nucleic acid amplification techniques on urine samples, the enrolled women were divided into two groups, i.e., “CT-negative” (n = 21) and “CT-positive”
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19

Ann Pereira, Loretta, Hilda Fernandes, and Amritha Chidambaram. "Implementing the Paris System into Reclassifying Urine Cytology: A Descriptive Analysis." International Journal of Science and Research (IJSR) 10, no. 11 (2021): 399–403. https://doi.org/10.21275/art20193124.

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20

SUZUKI, Yuji. "Spectrophotometric Determination of Urine Bilirubin by p-Dimethylaminobenzaldehyde." Analytical Sciences 14, no. 3 (1998): 609–12. http://dx.doi.org/10.2116/analsci.14.609.

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21

TOIDA, Toshihiko, Naoto KAKINUMA, Hidenao TOYODA, and Toshio IMANARI. "1H-NMR Profile of Glycosaminoglycans in Human Urine." Analytical Sciences 10, no. 4 (1994): 537–41. http://dx.doi.org/10.2116/analsci.10.537.

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22

Wagener, R. E., M. W. Linder, and R. Valdes. "Decreased signal in Emit assays of drugs of abuse in urine after ingestion of aspirin: potential for false-negative results." Clinical Chemistry 40, no. 4 (1994): 608–12. http://dx.doi.org/10.1093/clinchem/40.4.608.

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Abstract During routine drug analysis with the Syva d.a.u. Emit immunoassays we observed a high frequency of urines with lower rates of changes in absorbance (delta A R) than the rate for a drug-free urine calibrator. Many of these urines contained salicylates. Among 40 urines with apparent salicylate concentrations between 15 and 420 mg/dL tested for benzoylecgonine (BE), 20 had delta A R < -4 (range +2 to -28 mA/min). The rates decreased with increasing salicylate: delta A R = -0.057 x (salicylate, mg/dL) -0.22 mA/min (r = 0.85, n = 40, P < 0.01). Urines from 100 control subjec
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23

Naik, Dr Preeta. "A Study of Dipstick and Microscopic Analysis of Formed Elements in Urine." Journal of Medical Science And clinical Research 05, no. 04 (2017): 20485–88. http://dx.doi.org/10.18535/jmscr/v5i4.122.

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x, Sonu, Ruby Rani Agarwal, and Shashi Kant Tiwari. "Correlation of Urine Analysis with Mutrakriccha Types: A Modern and Ayurvedic Approach." International Journal of Science and Research (IJSR) 13, no. 10 (2024): 539–43. http://dx.doi.org/10.21275/sr241006205629.

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Dr, Mahmood Ahmad Zahid Dr Muhammad Ufeen Akram Dr Muzzamal Hussain. "ANALYSIS OF SPOT URINE PROTEIN TO CREATININE RATIO AS AN INDICATOR OF 24-HOUR URINARY PROTEIN EXCRETION IN NEPHROTIC SYNDROME." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 7432–38. https://doi.org/10.5281/zenodo.2636654.

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<strong><em>Introduction: </em></strong><em>Analysis of urine protein plays an important role in the evaluation of patients with suffering from renal disease. Analysis of 24h urine gathering was for quite a while the strategy for decision for measuring proteinuria however is never again suggested on the grounds of burden and imprecision because of human blunder in accumulation. </em> <strong><em>Aims and objectives: </em></strong><em>The basic aim of the study is to analyze spot urine protein vs creatinine ratio as a predictor of 24hr urinary protein excretion in nephrotic syndrome. </em> <str
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Sreedharan, Shilpa, John A. Petros, Viraj A. Master, et al. "Aquaporin-1 Protein Levels Elevated in Fresh Urine of Renal Cell Carcinoma Patients: Potential Use for Screening and Classification of Incidental Renal Lesions." Disease Markers 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/135649.

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Introduction and Objectives. There are over 65,000 new cases of renal cell carcinoma (RCC) each year, yet there is no effective clinical screening test for RCC. A single report claimed no overlap between urine levels of aquaporin-1 (AQP1) in patients with and without RCC (Mayo Clin Proc. 85:413, 2010). Here, we used archived and fresh RCC patient urine to validate this report.Methods. Archived RCC, fresh prenephrectomy RCC, and non-RCC negative control urines were processed for Western blot analysis. Urinary creatinine concentrations were quantified by the Jaffe reaction (Nephron 16:31, 1976).
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Abeje, Abebayehu. "Urine test strip analysis, concentration range and its interpretations of the parameters." GSC Biological and Pharmaceutical Sciences 22, no. 2 (2023): 001–13. https://doi.org/10.5281/zenodo.7919313.

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Urinalysis is a simple urine analysis performed in many healthcare settings and at home that reveals important diagnostic information. Diabetes mellitus, kidney failure, renal, liver diseases, hydration, urinary tract infection, and metabolic abnormalities are among the diseases studied. Urinalysis is simple to perform using a urine test strip, but the results must be correctly interpreted. Urinalysis is a noninvasive, widely available, and reasonably priced method. A urine test strip is a paper or plastic dipstick with a chemically impregnated pad that is one of the simplest, cheapest, and mo
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Perkins, S. L., and P. M. Johnson. "Loss of porphyrins from solution during analysis: effect of sample pH and matrix on porphyrin quantification in urine by "high-performance" liquid chromatography." Clinical Chemistry 35, no. 7 (1989): 1508–12. http://dx.doi.org/10.1093/clinchem/35.7.1508.

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Abstract We report the effect of sample matrix and pH on quantification of porphyrins by HPLC with fluorimetric detection. For aqueous solutions of pH less than 2.5, HPLC peak heights of the porphyrins increased with decreasing pH, reaching a plateau at pH less than 1.0. This loss of porphyrins from solutions with pH greater than 1.0 appeared to be due to a combination of microprecipitation and aggregation effects. No such "pH effect" was observed for urine samples supplemented with mixed-porphyrin standards. Addition of trace amounts of albumin to aqueous solutions also decreased these pH-rel
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FUSHINUKI, Yoshito, and Isao TANIGUCHI. "Determination of Methylamphetamine in Urine by Differential Pulse Polarography." Analytical Sciences 14, no. 2 (1998): 265–68. http://dx.doi.org/10.2116/analsci.14.265.

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M. SIMONET, Bartolomé, Félix GRASES, and Juan G. MARCH. "Enzymatic Determination of Pyrophosphate in Urine by Flow Methods." Analytical Sciences 19, no. 7 (2003): 1029–32. http://dx.doi.org/10.2116/analsci.19.1029.

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Ragone, Angela, Alessia Salzillo, Annamaria Spina, et al. "Protein Kinase A Detection in Human Urine Samples." Journal of Clinical Medicine 10, no. 18 (2021): 4096. http://dx.doi.org/10.3390/jcm10184096.

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Actively involved in tumor maintenance, cAMP-dependent protein kinase A (PKA) has been proposed as a putative biomarker in cancer. Recently, an active PKA form has been identified in human sera and PKA autoantibodies have been detected in cancer patients. However, their serum functions, as well as diagnostic significance, remain largely unknown. Although several PKA detection assays have been developed, none refer to a laboratory diagnostic procedure. Among these, ELISA and Western blotting (WB) assays have been employed in PKA detection. Since, to the best of our knowledge, there are no data
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Colston, K., N. J. Williams, and H. J. Cleeve. "Studies on vitamin D binding protein in the nephrotic syndrome." Clinical Chemistry 31, no. 5 (1985): 718–21. http://dx.doi.org/10.1093/clinchem/31.5.718.

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Abstract We studied the properties of vitamin D binding protein in plasma and urine from nine patients with nephrotic syndrome. Samples were incubated with 25-[3H]hydroxyvitamin D3, after which we determined binding capacity and apparent dissociation constants. Binding capacity was markedly less in plasma from patients with nephrotic syndrome than that from normal subjects, but binding affinity was unchanged. Specific binding of 25-hydroxy[3H]vitamin D3 could be demonstrated in urine from all the nephrotic patients, and sucrose density-gradient analysis of these urines revealed a single bindin
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Jackson, P. J., C. J. Sampson, E. H. Cooper, D. Heney, and J. T. Brocklebank. "Analysis of Proteinuria Using a Commercial System for Automated Electrophoresis and Isoelectric Focusing." Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 25, no. 3 (1988): 319–24. http://dx.doi.org/10.1177/000456328802500322.

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We describe an investigation of proteinuria using Pharmacia PhastSystem™ electrophoresis apparatus. The analysis of urinary proteins by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) of unconcentrated urine followed by silver staining took about 2 h and could clearly demonstrate tubular dysfunction or glomerular damage in urines with a negative or only trace-positive dip-stick test for protein. In addition, we show the identification of urinary proteins by immunoblotting from SDS-PAGE gels and the characterisation of Bence-Jones proteins by isoelectric focusing (IEF) and
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Ali, Nurshad, Ahsan Habib, Firoz Mahmud, Humaira Rashid Tuba, and Gisela H. Degen. "Aflatoxin M1 Analysis in Urine of Mill Workers in Bangladesh: A Pilot Study." Toxins 16, no. 1 (2024): 45. http://dx.doi.org/10.3390/toxins16010045.

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Presence of aflatoxin B1 (AFB1) in food and feed is a serious problem, especially in developing countries. Human exposure to this carcinogenic mycotoxin can occur through dietary intake, but also through inhalation or dermal contact when handling and processing AFB1-contaminated crops. A suitable biomarker of AFB1 exposure by all routes is the occurrence of its hydroxylated metabolite aflatoxin M1 (AFM1) in urine. To assess mycotoxin exposure in mill workers in Bangladesh, we analyzed AFM1 levels in urine samples of this population group who may encounter both dietary and occupational AFB1 exp
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KOBAYASHI, Ryusuke, and Keishichiro IMAIZUMI. "Determination of Tellurium in Urine by Hydride Generation Atomic Absorption Spectrometry." Analytical Sciences 7, no. 3 (1991): 447–50. http://dx.doi.org/10.2116/analsci.7.447.

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KATO, Noriyuki, Hiroaki KUBO, and Hiroshi HOMMA. "Fluorescence Analysis of p-Hydroxymethamphetamine in Urine by Thin-Layer Chromatography." Analytical Sciences 21, no. 9 (2005): 1117–19. http://dx.doi.org/10.2116/analsci.21.1117.

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NIWA, Toshifumi, Kazuhiro FUJITA, Toko KASUYA, Shigeo IKEGAWA, and Junichi GOTO. "Enzyme Immunoassay for Ursodeoxycholic Acid 7-N-Acetylglucosaminides in Human Urine." Analytical Sciences 12, no. 4 (1996): 565–68. http://dx.doi.org/10.2116/analsci.12.565.

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Bargotya, Mona, Lalit Kumar, Pinkey Kachhap, Payel Das, Vidushi Sachdeva, and Sonali Bhattar. "A Flow Cytometric and Cytochemistric Analysis of Urine to Detect Early Urinary Tract Infection." Annals of Pathology and Laboratory Medicine 7, no. 1 (2020): A7–12. http://dx.doi.org/10.21276/apalm.2659.

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39

Wilson, Thomas, Isabel Garcia-Perez, Joram M. Posma, et al. "Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measures of Dietary Exposure in Adults Using Metabolite Biomarkers." Journal of Nutrition 149, no. 10 (2019): 1692–700. http://dx.doi.org/10.1093/jn/nxz138.

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ABSTRACT Background Measurement of multiple food intake exposure biomarkers in urine may offer an objective method for monitoring diet. The potential of spot and cumulative urine samples that have reduced burden on participants as replacements for 24-h urine collections has not been evaluated. Objective The aim of this study was to determine the utility of spot and cumulative urine samples for classifying the metabolic profiles of people according to dietary intake when compared with 24-h urine collections in a controlled dietary intervention study. Methods Nineteen healthy individuals (10 mal
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Hemant, Dashora, Gaur Monica, Mehta Shefali, K. Verma A., Goyal Shuchi, and Mehta Vishwa. "Screening of Fluoride Level in Student Living in Tribal Hostel in and around Udaipur." International Journal of Pharmaceutical and Clinical Research 15, no. 7 (2023): 1363–67. https://doi.org/10.5281/zenodo.11934102.

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<strong>Background:&nbsp;</strong>The most of the fluoride in water is naturally occurring or available in added form of the free fluoride ion. The level of fluoride higher from 8mg/litter is having a significant harm on the body of an individual and leading to issues in urine. However, there are different technologies are available for maintaining and managing the level of fluoride in water but the lack of education and facilities in the rural and tribal areas is having a negative impact on the health of the people who are drinking the groundwater.&nbsp;<strong>Aim:&nbsp;</strong>The current
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SUNUNTA, Suphanan, Poomrat RATTANARAT, Orawon CHAILAPAKUL, and Narong PRAPHAIRAKSIT. "Microfluidic Paper-based Analytical Devices for Determination of Creatinine in Urine Samples." Analytical Sciences 34, no. 1 (2018): 109–13. http://dx.doi.org/10.2116/analsci.34.109.

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IINUMA, Fumio, Masayoshi TABARA, Makiko SUZUKI, and Mitsuo WATANABE. "Fluorometric determination of xanthurenic acid in urine with calcium nitrate and diethylamine." Analytical Sciences 4, no. 3 (1988): 317–20. http://dx.doi.org/10.2116/analsci.4.317.

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KAWAI, Satoshi, Ryota NISHIOKA, Masaharu NAKAHIGASHI, Kazuko KONDO, and Yuzi TAKAYAMA. "Determination of 3-keto-valproate in urine by metal capillary gas chromatography." Analytical Sciences 5, no. 3 (1989): 301–4. http://dx.doi.org/10.2116/analsci.5.301.

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HASHIZUME, Takeshi, Wataru TANIGUCHI, and Tamiji SUGIYAMA. "Mass spectrometric determination of N6-isopentenyladenosine and N6-isopentenyladenine from human urine." Analytical Sciences 2, no. 2 (1986): 157–59. http://dx.doi.org/10.2116/analsci.2.157.

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FAN, Jing, Yahong CHEN, Suling FENG, Cunling YE, and Jianji WANG. "Flow-Injection Spectrophotometric Determination of Sulfadiazine and Sulfamethoxazole in Pharmaceuticals and Urine." Analytical Sciences 19, no. 3 (2003): 419–22. http://dx.doi.org/10.2116/analsci.19.419.

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Calanchini, Matilde, Michael Tadman, Jesper Krogh, Andrea Fabbri, Ashley Grossman, and Brian Shine. "Measurement of urinary 5-HIAA: correlation between spot versus 24-h urine collection." Endocrine Connections 8, no. 8 (2019): 1082–88. http://dx.doi.org/10.1530/ec-19-0269.

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Background The 24-h urinary output of 5-hydroxyindoleacetic acid (5-HIAA) is used to monitor disease progression and treatment responses of neuroendocrine neoplasms (NENs). Several conditions are required for 5-HIAA assay, involving urine collection/preservation and food/drug restrictions. Aim To evaluate the correlation between 5-HIAA concentration in a spot urine sample and the output in a 24-h urine collection, and whether spot urine specimens can replace 24-h collection. Methods Patients with NENs or symptoms suggestive of NENs were asked to provide a separate spot urine at the end of the
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Froom, Paul, Barbara Bieganiec, Zahava Ehrenrich, and Mira Barak. "Stability of Common Analytes in Urine Refrigerated for 24 h before Automated Analysis by Test Strips." Clinical Chemistry 46, no. 9 (2000): 1384–86. http://dx.doi.org/10.1093/clinchem/46.9.1384.

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Abstract Background: Central outpatient laboratories might find processing large numbers of urinary samples that arrive in the late afternoon inconvenient and refrigerate them overnight before testing. Furthermore, in certain settings clinics might have difficulty assuring that the urine arrives at the laboratory during the same day as the collection. Because the stability of urine samples for delayed automated dipstick analysis (Supertron) is unknown, after defining precision, we retested urines refrigerated for 24 h to determine stability. Methods: Urinalysis was done twice on the same day a
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Hill, R. H., and S. L. Bailey. "Loss of coproporphyrin by centrifuging urine samples before liquid-chromatography." Clinical Chemistry 32, no. 2 (1986): 377–78. http://dx.doi.org/10.1093/clinchem/32.2.377.

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Abstract We have previously reported a "high-performance" liquid-chromatographic procedure for urinary porphyrins. While attempting to automate this procedure, we discovered that coproporphyrin could be partly or completely lost from urine samples if they were centrifuged or filtered before analysis. The loss is related to the amount of precipitate in each sample, acidic urines showing the greatest losses. If samples are alkalinized before centrifugation, the loss is prevented.
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Chi, Shuhong, Jing Xue, Xiaodong Chen, Xiaoming Liu, and Yanhong Ji. "Correlation of plasma and urine Wnt5A with the disease activity and cutaneous lesion severity in patients with systemic lupus erythematosus." Immunologic Research 70, no. 2 (2021): 174–84. http://dx.doi.org/10.1007/s12026-021-09253-w.

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AbstractReliable noninvasive biomarkers are needed to accurately assess disease activity and prognosis in patients with systemic lupus erythematosus (SLE). The purpose of this study was to investigate the clinical relevance of Wnt5A with disease activity and severity with cutaneous involvement in particular in SLE patients; its concentrations in plasma and urine were examined and analyzed. In the cross-sectional study, the clinical relevance of Wnt5A protein was evaluated in both plasma and urine of SLE patients and healthy cohorts using commercial enzyme-linked immunosorbent assays (ELISA). S
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van den Bosch, Thierry P., Geert J. L. H. van Leenders, Siamala Sinnadurai, et al. "Abstract 1073: AI-assisted high-dimensional cytological single cell analysis distinguishes normal and malignant urine samples using cell morphology images with high accuracy at the single cell level." Cancer Research 84, no. 6_Supplement (2024): 1073. http://dx.doi.org/10.1158/1538-7445.am2024-1073.

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Abstract Background: Urothelial cancer (UCC) is the 4th most common malignancy in men. The current clinical problem in UCC management is the high interobserver variability of tissue UCC grading and the low sensitivity of urine cytology for early detection of recurrences and progression. We hypothesize that assessing urine samples and UCC tissues with detailed quantitative image analysis based on artificial intelligence has strong potential in both urine-based early detection of tumor recurrence and progression as well as tissue-based pathological grading. Methods: Here, we utilized the Deepcel
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