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1

An, Jun Xiu. "Research and Implementation on the Cloud of Chinese Letter." Advanced Materials Research 219-220 (March 2011): 1707–11. http://dx.doi.org/10.4028/www.scientific.net/amr.219-220.1707.

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The Chinese word clouds can view the Chinese documents based on users’ input or URL web sites, in accordance with the appearing frequency of words in the documents to generate a multi-state performance image, similar to the cloud images, namely, "word cloud". This system first obtains Chinese documents users view, cuts up words to the documents, then counts the frequency of each word, and finally puts the words on the appropriate framework based on the high or low word frequency, showing an effect of "word cloud". This system uses the hash algorithm making the output fonts not overlap, and gen
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2

Mehlhorn, Hendrik, Matthias Lange, Uwe Scholz, and Falk Schreiber. "IDPredictor: predict database links in biomedical database." Journal of Integrative Bioinformatics 9, no. 2 (2012): 1–15. http://dx.doi.org/10.1515/jib-2012-190.

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Summary Knowledge found in biomedical databases, in particular in Web information systems, is a major bioinformatics resource. In general, this biological knowledge is worldwide represented in a network of databases. These data is spread among thousands of databases, which overlap in content, but differ substantially with respect to content detail, interface, formats and data structure. To support a functional annotation of lab data, such as protein sequences, metabolites or DNA sequences as well as a semi-automated data exploration in information retrieval environments, an integrated view to
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3

Bergland, Ola Undrum, Lene V. Halvorsen, Camilla L. Søraas, et al. "Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations." Hypertension 78, no. 3 (2021): 617–28. http://dx.doi.org/10.1161/hypertensionaha.121.17514.

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Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in a nationwide multicenter study. Five hundred fifty patients with hypertension using ≥2 antihypertensive agents participated. We measured concentrations of 23 antihypertensive drugs using ultra high performance liquid chromatography tandem mass-spectrometry and compared with patients’ self-reports and investigators’ assessment based on structured interview. We identified 40 no
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J. Santhosh Kumar, B., and Kankanala Pujitha. "Web Application Vulnerability Detection Using Hybrid String Matching Algorithm." International Journal of Engineering & Technology 7, no. 3.6 (2018): 106. http://dx.doi.org/10.14419/ijet.v7i3.6.14950.

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Application uses URL as contribution for Web Application Vulnerabilities recognition. if the length of URL is too long then it will consume more time to scan the URL (Ain Zubaidah et.al 2014).Existing system can notice the web pages but not overall web application. This application will test for URL of any length using String matching algorithm. To avoid XSS and CSRF and detect attacks that try to sidestep program upheld arrangements by white list and DOM sandboxing techniques (Elias Athanasopoulos et.al.2012). The web application incorporates a rundown of cryptographic hashes of legitimate (t
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5

Barba, Pere, Albert Oriol, Carlos Grande, et al. "Intensive Immunochemotherapy In Patients With B-Cell Lymphoma, Unclassifiable (B-UCL), With Features Intermediate Between Diffuse Large B-Cell Lymphoma (DLBCL) and Burkitt Lymphoma (BL): A Comparison With BL Patients Treated With The Same Protocol In The Pethema-Burkimab-04 Trial." Blood 122, no. 21 (2013): 1793. http://dx.doi.org/10.1182/blood.v122.21.1793.1793.

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Abstract B-UCL is a new category of lymphomas that comprises a heterogeneous group of tumors from a morphological, phenotypic and genetic perspective with features intermediate between DLBCL and BL. This entity has been included as a new category in the 2008 World Health Organization (WHO) Classification of Tumors of Hematopoietic and Lymphoid Tissues. The outcome of patients with B-UCL is generally considered very poor. However, the number of series analyzing the prognosis of B-UCL is scarce and they include small number of patients not homogeneously treated. Against this background, herein w
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Edward Phillips, Mark, Daniel Gelaw Alemneh, and Brenda Reyes Ayala. "Analysis of URL references in ETDs: a case study at the University of North Texas." Library Management 35, no. 4/5 (2014): 293–307. http://dx.doi.org/10.1108/lm-08-2013-0073.

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Purpose – Increasingly, higher education institutions worldwide are accepting only electronic versions of their students’ theses and dissertations. These electronic theses and dissertations (ETDs) frequently feature embedded URLs in body, footnote and references section of the document. Additionally the web as ETD subject appears to be on an upward trajectory as the web becomes an increasingly important part of everyday life. The paper aims to discuss these issues. Design/methodology/approach – The authors analyzed URL references in 4,335 ETDs in the UNT ETD collection. Links were extracted fr
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7

Roth, Travis S., David P. Beason, T. Bradley Clay, E. Lyle Cain, and Jeffrey R. Dugas. "The Effect of Ulnar Collateral Ligament Repair With Internal Brace Augmentation on Articular Contact Mechanics: A Cadaveric Study." Orthopaedic Journal of Sports Medicine 9, no. 4 (2021): 232596712110010. http://dx.doi.org/10.1177/23259671211001069.

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Background: There has been renewed interest in ulnar collateral ligament (UCL) repair in throwing athletes because of a greater understanding of UCL injuries, improvement in ligament repair technology, and potentially expedited rehabilitation time and return to play relative to UCL reconstruction. Purpose: To evaluate elbow articular contact and overall joint torque after UCL reconstruction and repair augmented with a collagen-coated fiber tape, InternalBrace. Study Design: Controlled laboratory study. Methods: Ten matched pairs of cadaveric arms (mean age, 41 ± 11 years) were dissected to exp
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SÜREN, Emre, Pelin ANGIN, and Nazife BAYKAL. "I see EK: A lightweight technique to reveal exploit kit family by overall URL patterns of infection chains." TURKISH JOURNAL OF ELECTRICAL ENGINEERING & COMPUTER SCIENCES 27, no. 5 (2019): 3713–28. http://dx.doi.org/10.3906/elk-1810-199.

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9

Zainuddin, Nuryani, Mohamad Samsul Maarif, Etty Riani, and Susan Maphilindawati Noor. "PERAN KARAKTERISTIK, PENGETAHUAN DAN SIKAP PEKERJA TERHADAP PRAKTIK PENGELOLAAN LIMBAH DI INSTALASI KARANTINA HEWAN (Characteristics, Knowledge and Attitude of Workers Regarding Waste Management Practices in Animal Quarantine Installations)." Jurnal Manusia dan Lingkungan 27, no. 1 (2020): 24. http://dx.doi.org/10.22146/jml.40808.

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AbstrakLimbah Instalasi Karantina Hewan (IKH) ruminansia besar dapat menjadi sumber penularan penyakit yang mungkin terbawa akibat lalu lintas ternak serta dapat menimbulkan permasalahan lingkungan. Tujuan penelitian ini untuk menganalisis sejauh mana karakteristik, pengetahuan dan sikap petugas IKH berpengaruh terhadap praktik pengelolaan limbah di IKH. Responden adalah petugas yang melakukan pengelolaan limbah di IKH. Hubungan dan tingkat pengaruh langsung dan tidak langsung pada variabel yang diamati dianalisis menggunakan analisis jalur (path analysis). Hasil penelitian menunjukkan secara
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10

Assegie, Tsehay Admassu. "K-Nearest Neighbor Based URL Identification Model for Phishing Attack Detection." Indian Journal of Artificial Intelligence and Neural Networking 1, no. 2 (2021): 18–21. http://dx.doi.org/10.35940/ijainn.b1019.041221.

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Phishing causes many problems in business industry. The electronic commerce and electronic banking such as mobile banking involves a number of online transaction. In such online transactions, we have to discriminate features related to legitimate and phishing websites in order to ensure security of the online transaction. In this study, we have collected data form phish tank public data repository and proposed K-Nearest Neighbors (KNN) based model for phishing attack detection. The proposed model detects phishing attack through URL classification. The performance of the proposed model is teste
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Torane, Shailendra Baliram, and Dr Narendra Shekokar. "Performance Analysis of Machine Learning Algorithms Used for Web Based Phishing Detection." Journal of University of Shanghai for Science and Technology 23, no. 05 (2021): 650–56. http://dx.doi.org/10.51201/jusst/21/05187.

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Phishing is a cybercrime technique in which the attacker creates a copy of genuine websites with the same color pattern, layout, font, and logo and with a domain name that matches with the real one. Then, broadcast this fake website through various online modes like emails and social media. The attacker creates lucrative offers or discounts to lure in people to click on the phishing link. Once the user clicks on this phishing link, they a re directed to the duplicate website that the attacker had created. The user believes that it is the real website and enters his/her login details and other
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Bahr, Katherine L., Lisa Howe, Carl Jessen, and Zachary Goodrich. "Outcome of 45 Dogs With Laryngeal Paralysis Treated by Unilateral Arytenoid Lateralization or Bilateral Ventriculocordectomy." Journal of the American Animal Hospital Association 50, no. 4 (2014): 264–72. http://dx.doi.org/10.5326/jaaha-ms-6081.

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The purpose of this retrospective study was to assess risk factors and complications affecting postoperative outcome of dogs with laryngeal paralysis treated by either unilateral arytenoid lateralization (UAL) or bilateral ventriculocordectomy (VCC). Medical records of all dogs having either UAL or VCC between 2000 and 2011 were analyzed. Twenty-five dogs had VCC and 20 dogs had UAL. The overall postoperative complications rates for VCC and UAL were similar (52% and 60%, respectively; P = .0887). Dogs that had UAL were more likely to have acute postoperative respiratory distress and aspiration
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13

Jacobsohn, David A., Mukta Arora, John P. Klein, et al. "Risk factors associated with increased nonrelapse mortality and with poor overall survival in children with chronic graft-versus-host disease." Blood 118, no. 16 (2011): 4472–79. http://dx.doi.org/10.1182/blood-2011-04-349068.

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Abstract There is a paucity of information regarding the factors that affect nonrelapse mortality (NRM) and overall survival among children that develop chronic graft-versus-host disease (cGVHD). We performed multivariate analyses using data from the Center for International Blood and Marrow Transplant Research to identify risk factors for NRM and survival in 1117 pediatric subjects with leukemia or myelodysplastic syndrome, transplanted from related donors, unrelated donors (URD), or unrelated cord blood between 1995 and 2004. We identified 4 variables associated with higher NRM: HLA partiall
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14

Hao, Zhi Feng, Ze Bin Zhang, Zhao Quan Cai, and Han Huang. "An Improved Crawler Algorithm Based on Hierarchical Structure Preservation." Key Engineering Materials 474-476 (April 2011): 2120–24. http://dx.doi.org/10.4028/www.scientific.net/kem.474-476.2120.

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This paper proposes an improved web crawler algorithm to climb more useful information since the basic web crawler algorithm is low-efficiency and easy to climb useless repeated information. By the proposed algorithm, the website urls are hierarchical saved to store websites overall topology, which will make crisscross complex web URL system from a graphic structure into a tree structure. The actual website BBS experiments show that the algorithm is much better than the basic web crawler algorithm in crawling speed and download information such as the usefulness of baking. Furthermore, it prov
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15

Walker, Clark M., James W. Genuario, Darby A. Houck, Scott Murayama, Hanna Mendez, and Thomas J. Noonan. "Return-to-Play Outcomes in Professional Baseball Players After Nonoperative Treatment of Incomplete Medial Ulnar Collateral Ligament Injuries: A Long-Term Follow-up Study." American Journal of Sports Medicine 49, no. 5 (2021): 1137–44. http://dx.doi.org/10.1177/0363546521996706.

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Background: Medial ulnar collateral ligament (UCL) injuries are common among baseball players. There is sparse literature on long-term results after nonoperative treatment of UCL injuries in professional baseball players. Purpose: The primary purpose was to assess long-term follow-up on reinjury rates, performance metrics, rate of return to the same level of play or higher (RTP), and ability to advance to the next level of play in professional baseball players after nonoperative treatment of incomplete UCL injuries. The secondary aim was to perform a matched-pair comparison between pitchers tr
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16

Chen, Yi-Bin, Julie Aldridge, Haesook Kim, et al. "Reduced Intensity Conditioning (RIC) with Double Umbilical Cord Blood Transplantation Has Similar Outcomes Compared to RIC Transplantation From Related or Unrelated Adult Donors." Blood 116, no. 21 (2010): 2367. http://dx.doi.org/10.1182/blood.v116.21.2367.2367.

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Abstract Abstract 2367 Umbilical cord blood is generally regarded as an alternative source of stem cells for patients who lack a well matched related or unrelated donor, but there are little data comparing stem cell sources after reduced intensity conditioning (RIC) SCT. We performed a retrospective study comparing outcomes after RIC SCT using related donors (RD), unrelated donors (URD), and double umbilical cord blood (dUCB) from two partner institutions. Retrospective database review was performed for patients undergoing reduced intensity stem cell transplants from related and unrelated dono
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Saraceni, Francesco, Myriam Labopin, Norbert Claude Gorin, et al. "Comparison of Matched/Mismatched Unrelated Donor Stem Cell Transplantation to Autologous Stem Cell Transplantation for Acute Myeloid Leukemia in First Complete Remission: A Study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)." Blood 126, no. 23 (2015): 3216. http://dx.doi.org/10.1182/blood.v126.23.3216.3216.

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Abstract Background. Optimal post-remission strategy for patients with acute myeloid leukemia (AML) is still matter of debate. Allogeneic Stem Cell Transplant (allo-HSCT) is the most effective treatment to prevent leukemia relapse, and for patients who lack a sibling donor transplantation from a matched or mismatched unrelated donor (URD) is usually the preferred alternative. However, increase in donor-recipient HLA mismatch, patient age and comorbidity scores lead to higher non relapse mortality (NRM) rates; moreover incidence of chronic GVHD is rather high after transplant from unrelated don
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18

Buckley, Patrick S., Elizabeth R. Morris, Colin M. Robbins, et al. "Variations in Blood Supply From Proximal to Distal in the Ulnar Collateral Ligament of the Elbow: A Qualitative Descriptive Cadaveric Study." American Journal of Sports Medicine 47, no. 5 (2019): 1117–23. http://dx.doi.org/10.1177/0363546519831693.

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Background: The vascular supply of the ulnar collateral ligament (UCL) is unknown. Previous studies reported varying success in return-to-play rates after nonoperative management of partial UCL tears and suggested a varying healing capacity as possibly related to the location of the UCL injury. Purpose: To analyze the macroscopic vascular anatomy of the UCL of the elbow. Study Design: Descriptive laboratory study. Methods: Eighteen fresh-frozen male cadaveric elbows from 9 donors were sharply dissected 15 cm proximal to the medial epicondyle. Sixty milliliters of India ink was injected through
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19

SUMOD, K. S., ANIL MOHAPATRA, V. N. SANJEEVAN, T. G. KISHOR, and K. K. BINEESH. "A new species of white-spotted moray eel, Gymnothorax smithi (Muraenidae: Muraeninae) from deep waters of Arabian Sea, India." Zootaxa 4652, no. 2 (2019): 359–66. http://dx.doi.org/10.11646/zootaxa.4652.2.8.

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A new species of white-spotted moray eel Gymnothorax smithi sp. nov. is described based on three specimens collected from the southeastern Arabian Sea, India. This is the first deep water report of a moray eel from Indian waters from 200 m depth. This new species is distinguishable from its congeners by the following combination of characters: greyish brown body overlain with white spots of irregular shape, dorsal-fin origin anterior to gill opening, anus positioned slightly behind the mid-point of the body, serrated teeth and a unique vertebral count 3–5 /57/130–132. [Zoobank URL: urn:lsid:zo
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20

Qiao, Lin, Huiping Huang, and Yichen Tian. "The Identification and Use Efficiency Evaluation of Urban Industrial Land Based on Multi-Source Data." Sustainability 11, no. 21 (2019): 6149. http://dx.doi.org/10.3390/su11216149.

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Urban industrial land (UIL), which is classified for industrial purposes, is an indispensable component of urban land. Obtaining up-to-date and timely UIL details from the industrial development perspective has practical significance for UIL planning. Therefore, we propose a practical method for integrating UIL identification and use efficiency evaluation at the parcel scale based on multi-source data. The Open Street Map (OSM) data were utilized to generate parcels, which served as basic analytical units. Point of Interest (POI) data combined with a Continuous Bag-of-Words (CBoW)-based Word2V
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Buckley, Patrick S., Elizabeth R. Morris, Colin Robbins, et al. "Variations in Blood Supply from Proximal to Distal in the Ulnar Collateral Ligament of the Elbow: A Qualitative Descriptive Cadaveric Study." Orthopaedic Journal of Sports Medicine 7, no. 7_suppl5 (2019): 2325967119S0036. http://dx.doi.org/10.1177/2325967119s00361.

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Objectives: The vascular supply of the ulnar collateral ligament (UCL) is unknown. Previous studies have reported varying success in return to play rates after non-operative management of partial UCL tears and suggest a varying healing capacity as possibly related to UCL injury location. The purpose of this study was to analyze the macroscopic vascular anatomy of the ulnar collateral ligament of the elbow. Methods: Eighteen, fresh-frozen, male cadaveric elbows from nine donors were sharply dissected 15 cm proximal to the medial epicondyle. Sixty mL of India Ink was injected through the brachia
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22

Kim, Hyoung Tae, and Alfred L. Goldberg. "UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells." Proceedings of the National Academy of Sciences 115, no. 50 (2018): E11642—E11650. http://dx.doi.org/10.1073/pnas.1808731115.

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The best-known function of ubiquitin-like (UBL) domains in proteins is to enable their binding to 26S proteasomes. The proteasome-associated deubiquitinating enzyme Usp14/UBP6 contains an N-terminal UBL domain and is an important regulator of proteasomal activity. Usp14 by itself represses multiple proteasomal activities but, upon binding a ubiquitin chain, Usp14 stimulates these activities and promotes ubiquitin-conjugate degradation. Here, we demonstrate that Usp14’s UBL domain alone mimics this activation of proteasomes by ubiquitin chains. Addition of this UBL domain to purified 26S protea
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23

Gupta, Vikas, Martin S. Tallman, Wensheng He, et al. "Comparable Disease-Free and Overall Survival After “Well-Matched” Unrelated Donor and Matched Sibling Donor Transplantation in Acute Myeloid Leukemia with Adverse Risk Karyotype in First Complete Remission: A Report From the Acute Leukemia Working Committee of the Centre for International Blood and Marrow Transplant Research." Blood 114, no. 22 (2009): 526. http://dx.doi.org/10.1182/blood.v114.22.526.526.

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Abstract Abstract 526 In patients with acute myeloid leukemia (AML) in first complete remission (CR1), the indications for matched sibling donor (MSD) transplants and unrelated donor (URD) haemopoietic stem cell transplantation (HSCT) are different. We sought to determine the prognostic impact of donor type on the outcomes of AML with adverse risk karyotype in CR1, a high-risk AML population considered as a standard indication for MSD and URD HSCT. We evaluated the outcomes of 584 patients undergoing allogeneic HSCT for AML with adverse risk karyotype in CR1 between 1995 and 2006, reported to
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Apple, Fred S., Alan H. B. Wu, Yader Sandoval, et al. "Sex-Specific 99th Percentile Upper Reference Limits for High Sensitivity Cardiac Troponin Assays Derived Using a Universal Sample Bank." Clinical Chemistry 66, no. 3 (2020): 434–44. http://dx.doi.org/10.1093/clinchem/hvz029.

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Abstract Background How to select healthy reference subjects in deriving 99th percentiles for cardiac troponin assays still needs to be clarified. To assist with global implementation of high sensitivity (hs)-cardiac troponin (cTn) I and hs-cTnT assays in clinical practice, we determined overall and sex-specific 99th percentiles in 9 hs-cTnI and 3 hs-cTnT assays using a universal sample bank (USB). Methods The Universal Sample Bank (USB) comprised healthy subjects, 426 men and 417 women, screened using a health questionnaire. Hemoglobin A1c (>URL 6.5%), NT-proBNP (>URL 125 ng/L)
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Reis, Henning, Ulrich Krafft, Christian Niedworok, et al. "Biomarkers in Urachal Cancer and Adenocarcinomas in the Bladder: A Comprehensive Review Supplemented by Own Data." Disease Markers 2018 (2018): 1–21. http://dx.doi.org/10.1155/2018/7308168.

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Urachal cancer (UrC) is a rare but aggressive cancer. Due to overlapping histomorphology, discrimination of urachal from primary bladder adenocarcinomas (PBAC) and adenocarcinomas secondarily involving the bladder (particularly colorectal adenocarcinomas, CRC) can be challenging. Therefore, we aimed to give an overview of helpful (immunohistochemical) biomarkers and clinicopathological factors in addition to survival analyses and included institutional data from 12 urachal adenocarcinomas. A PubMed search yielded 319 suitable studies since 1930 in the English literature with 1984 cases of UrC
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26

Erickson, Brandon J., Bernard R. Bach, Nikhil N. Verma, Charles A. Bush-Joseph, and Anthony A. Romeo. "Treatment of Ulnar Collateral Ligament Tears of the Elbow." Orthopaedic Journal of Sports Medicine 5, no. 1 (2017): 232596711668221. http://dx.doi.org/10.1177/2325967116682211.

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Background: Ulnar collateral ligament (UCL) tears have become common, and UCL reconstruction (UCLR) is currently the preferred surgical treatment method for treating UCL tears. Purpose/Hypothesis: The purpose of this study was to review the literature surrounding UCL repair and determine the viability of new repair techniques for treatment of UCL tears. We hypothesized that UCL repair techniques will provide comparable results to UCLR for treatment of UCL tears. Study Design: Systematic review and meta-analysis; Level of evidence, 4. Methods: A systematic review was registered with PROSPERO an
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27

Hu, Jiong, han-Bo Dou, Ling Wang, and Wei Tang. "The Superiority of Allogeneic Hematopoietic Stem Cell Transplantation From Unrelated Donor Over Chemotherapy As Post-Remission Treatment for Patients with High-Risk Acute Lymphoblastic Leukemia in First Remission." Blood 120, no. 21 (2012): 1986. http://dx.doi.org/10.1182/blood.v120.21.1986.1986.

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Abstract Abstract 1986 For adult patients with acute lymphoblastic leukemia (ALL), allogeneic hematopoietic stem cell transplantation (allo-HSCT) from HLA-matched related donor (MSD) is recommended for standard and high-risk patients. The role of unrelated donor transplantation (URD) is not fully determined. In this single-center retrospective analysis, we included all consecutive adult patients with high-risk ALL in 1st complete remission (CR) without sibling donor between Jan 2007 to June 2012. Overall, 74 patients were included in the analysis in which 32 patients received URD allo-HSCT dur
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Wang, Mou, Wenmei Kang, Ruiying Zhang, and Jianhong (Cecilia) Xia. "The Gap between Urban and Rural Development Levels Narrowed." Complexity 2020 (September 28, 2020): 1–10. http://dx.doi.org/10.1155/2020/4615760.

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The difference between urban and rural development levels (URDL) and the deficiency of rural development level have become the weak points for China to achieve balanced and high-quality development. In order to reveal the changing trend of urban-rural differences in China over the years and provide a reference for the policy-making of the balanced development of urban and rural areas and high-quality economic development, this paper uses the United Nations Development Program-adjusted Human Development Index (HDI) calculation method to calculate the urban and rural areas, based on 1995–2017 na
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29

Rao, Somnath, Robert Jack, Donald Willier, et al. "Ulnar Collateral Ligament Injury in Gymnasts: An Analysis of Return to Competition Rates and Patient Outcomes." Orthopaedic Journal of Sports Medicine 9, no. 7_suppl4 (2021): 2325967121S0020. http://dx.doi.org/10.1177/2325967121s00200.

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Objectives: While results following ulnar collateral ligament (UCL) injury in baseball players has been well documented, results following UCL injury in gymnasts are not well documented. As such, the purpose of this study was to report the operative and non-operative outcomes of UCL injury in gymnasts. Methods: Gymnasts who underwent UCL injury treatment whether non-operative or operative at a single institution were evaluated at a minimum of 2 years post-operatively. Patients were assessed with Kerlan-Jobe Orthopaedic Clinic Shoulder and Elbow Score (KJOC), Mayo Elbow Performance Score (MEPS)
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Vance, Danica D., Frank J. Alexander, Brian W. Kunkle, Mark Littlefield, and Christopher S. Ahmad. "Professional and Amateur Pitchers’ Perspective on the Ulnar Collateral Ligament Injury Risk." Orthopaedic Journal of Sports Medicine 7, no. 6 (2019): 232596711985077. http://dx.doi.org/10.1177/2325967119850777.

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Background: Medial ulnar collateral ligament (UCL) injury is increasingly prevalent in professional baseball pitchers, and significant research has been devoted to understanding the risk factors and prevention strategies associated with it. To date, no study has investigated what the players themselves believe causes and prevents the injury. Purpose: To evaluate the opinions of UCL injuries among pitchers, including professional athletes. Study Design: Cross-sectional study. Methods: A total of 214 baseball pitchers (45 high school/college, 169 Major League Baseball [MLB]/Minor League Baseball
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Hillyer, Grace Clarke, Melissa Beauchemin, Philip Garcia, et al. "Readability of Cancer Clinical Trials Websites." Cancer Control 27, no. 1 (2020): 107327481990112. http://dx.doi.org/10.1177/1073274819901125.

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Clinical trials are critically important for the development of new cancer treatments. According to recent estimates, however, clinical trial enrollment is only about 8%. Lack of patient understanding or awareness of clinical trials is one reason for the low rate of participation. The purpose of this observational study was to evaluate the readability of cancer clinical trial websites designed to educate the general public and patients about clinical trials. Nearly 90% of Americans use Google to search for health-related information. We conducted a Google Chrome Incognito search in 2018 using
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Liu, Qifa, Jing Sun, Dan Xu, et al. "Clinical Effects of Unrelated-Donor or Related-Donor Hematopoietic Stem Cell Transplantation for Leukemia." Blood 106, no. 11 (2005): 5436. http://dx.doi.org/10.1182/blood.v106.11.5436.5436.

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Abstract Patients and Methods: From February 2003 to May 2005, 118 patients with leukemia received URD-HSCT or RD-HSCT at our institution. 43 cases received URD-HSCT and 75 cases received RD-HSCT. The basic conditioning regimens were TBI (total-body irradiation) + CY (CTX) protocol or modified BuCY (hydroxyurea, busulfan, Ara-C and CTX) protocol. Fludarabine, cytosine arabinoside, etoposide and etc. were added to the basic conditioning regimens when treated patients with refractory leukemia or in NR. The 43 patients who were treated with URD-HSCT, included 43 patients matched at 6/6 HLA antige
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Gao, Chunji, Xiaohong Li, Honghua Li, et al. "Comparative Analysis of Outcomes of Allogeneic Peripheral Blood Stem Cell Transplantation From Related and Unrelated Donors for Adults with Hematologic Malignancies." Blood 116, no. 21 (2010): 2302. http://dx.doi.org/10.1182/blood.v116.21.2302.2302.

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Abstract Abstract 2302 Although allogeneic peripheral blood stem cell transplantation from a matched related donor (RD-PBSCT) presents the best curable opportunity for many patients with hematologic malignancies, only about one third of individuals have HLA matched sibling donors. Fortunately, from unrelated donor peripheral blood stem cell transplantation has been acceptable and expanded recently. In order to evaluate the effect of allogeneic peripheral blood stem cell transplantation from unrelated donor (URD-PBSCT), we compare results of URD-PBSCT and RD-PBSCT that were done for 172 consecu
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34

Fleischhauer, Katharina. "Selection of matched unrelated donors moving forward: from HLA allele counting to functional matching." Hematology 2019, no. 1 (2019): 532–38. http://dx.doi.org/10.1182/hematology.2019000057.

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Abstract Matched unrelated donors (URD) are the most frequent source of stem cells for allogeneic hematopoietic cell transplantation (HCT) to date, with HCT performed mainly under conventional immunosuppression by methotrexate and cyclosporine. In this setting, every single allelic donor–recipient mismatch for HLA-A, -B, -C, -DRB1 (8/8), but not for HLA-DQB1, -DPB1, has a significant negative effect on overall survival (OS). When several 8/8 HLA-matched URD are available, donor age is the most important factor impacting OS. Moving forward from the traditional way of counting the number of dono
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Keilholz, U., S. Suciu, A. Y. Bedikian, et al. "LDH is a prognostic factor in stage IV melanoma patients (pts) but is a predictive factor only for bcl2 antisense treatment efficacy: Re-analysis of GM301 and EORTC18951 randomized trials." Journal of Clinical Oncology 25, no. 18_suppl (2007): 8552. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.8552.

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8552 Background: Two large studies with identical eligibility criteria and using serum LDH as stratification for randomization were re-analyzed in order to 1) confirm the prognostic importance of LDH in advanced melanoma; 2) to assess whether an interaction between LDH and treatment efficacy exists. Methodology: Oblimersen (OBL) trial GM301 randomized 771 pts between DTIC vs. DTIC+OBL, whereas EORTC trial 18951 randomized 365 pts between biochemotherapy vs biochemotherapy+IL2 (JCO, 2004). LDH was divided into 5 groups: 5 UNL. Cox model was used to asses the prognostic importance of LDH, treatm
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36

Liu, Qifa, Kai Yang, Zhiping Fan, et al. "Comparison of Therapeutic Effect between Related Donor and Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) in the Treatment of Leukemia." Blood 108, no. 11 (2006): 5389. http://dx.doi.org/10.1182/blood.v108.11.5389.5389.

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Abstract Objective : To compare the effect for leukemia between related donor hematopoietic stem cell transplantation (RD-HSCT) and unrelated donor hematopoietic stem cell transplantation (URD-HSCT). Methods: 115 patients received allo-HSCT, of whom 68 received RD-HSCT and 47 received URD-HSCT. All patients are HLA serologically matched. Total body irradiation (TBI) plus cyclophosphamide (CTX) was adopted in 56 cases and modified BuCY conditioning regimen (busulfan, Ara-C, Cyclophosphamide) in 59 cases. T and B cell reconstitution at different time points was assayed by flow cytometer in one y
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37

Weisdorf, Daniel J., Mary Eapen, Annalisa Ruggeri, et al. "Alternative Donor Hematopoietic Transplantation For Patients Older Than 50 Years With AML In First Complete Remission: Unrelated Donor and Umbilical Cord Blood Transplantation Outcomes." Blood 122, no. 21 (2013): 302. http://dx.doi.org/10.1182/blood.v122.21.302.302.

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Abstract Post-remission allogeneic transplantation is increasingly used for treatment of the high-risk acute myeloid leukemia (AML) affecting older adults. We analyzed 740 adults over age 50 with AML in first complete remission (CR1) to compare the effectiveness of volunteer unrelated donor (URD) and umbilical cord blood (UCB) graft sources in providing a successful transplant. For prospective cases reported (2005-2010) to the Center for International Blood and Marrow Transplant Research and Eurocord, we evaluated 8/8 HLA allele matched (at HLA-A, -B, -C, -DRB1) n=441; 7/8 matched URD n=94 and
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38

Punch, Jerry, Antony Joseph, and Brad Rakerd. "Most Comfortable and Uncomfortable Loudness Levels." American Journal of Audiology 13, no. 2 (2004): 144–57. http://dx.doi.org/10.1044/1059-0889(2004/019).

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This article critically reviews the influence of such factors as psychophysical testing method, stimulus type, and instructional set on most comfortable loudness (MCL) and uncomfortable loudness (UCL) levels. Generally, research indicates that test methods and instructions strongly affect both MCL and UCL while stimulus conditions affect them less substantially. Overall, the data suggest lower reliability for MCL than for UCL and lower reliability for pure-tone MCLs than for speech MCLs. Lower MCLs are typically obtained when measured by an ascending approach, in contrast to a descending appro
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39

Gupta, Vikas, Martin S. Tallman, Wensheng He, et al. "Comparable survival after HLA-well-matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosis." Blood 116, no. 11 (2010): 1839–48. http://dx.doi.org/10.1182/blood-2010-04-278317.

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AbstractWe compared the outcomes of unrelated donor (URD, n = 358) with human leukocyte antigen (HLA)–matched sibling donor (MSD, n = 226) transplantations in patients with acute myeloid leukemia (AML) in first complete remission (CR1) having unfavorable cytogenetics at diagnosis. Unfavorable cytogenetic abnormalities were: complex (≥ 3 abnormalities), 32%; and noncomplex involving chromosome 7, 25%; chromosome 5, 9%; 11q or MLL rearrangements, 18%; t(6;9), 5%; and other noncomplex, 10%. URDs were HLA-well-matched (n = 254; 71%) or partially-matched (n = 104; 29%). Three-year leukemia-free sur
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40

Molenaars, Rik J., Michel P. J. van den Bekerom, Mark R. Nazal, Denise Eygendaal, and Luke S. Oh. "Clinical Value of an Acute Popping Sensation in Throwing Athletes With Medial Elbow Pain for Ulnar Collateral Ligament Injury." Orthopaedic Journal of Sports Medicine 8, no. 1 (2020): 232596711989327. http://dx.doi.org/10.1177/2325967119893275.

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Background: Throwing athletes sustaining an ulnar collateral ligament (UCL) injury may recall a popping sensation originating from the medial elbow at the time of injury. There are no studies available that inform clinicians how to utilize this salient anamnestic information and what amount of diagnostic weight to afford to it. Purpose: To assess the diagnostic value of a popping sensation for significant UCL injury in throwing athletes who sustained an injury causing medial elbow pain. Study Design: Cohort study (prognosis); Level of evidence, 3. Methods: A total of 207 consecutive patients w
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41

Bachanova, Veronika, Claudio Brunstein, Linda J. Burns, et al. "Alternative Donor Transplantation For Adults With Lymphoma: Comparison Of Umbilical Cord Blood Versus 8/8 HLA-Matched Donor (URD) Versus 7/8 URD." Blood 122, no. 21 (2013): 161. http://dx.doi.org/10.1182/blood.v122.21.161.161.

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Abstract Allogeneic donor hematopoietic cell transplantation (HCT) is increasingly used to treat relapsed lymphoma with curative intent; however, many patients will not have a suitable matched sibling donor. Transplant centers are investigating the use of alternative stem cell sources although data comparing outcomes by stem cell source are limited. We compared outcomes of 1593 non-Hodgkin and Hodgkin lymphoma patients who underwent alternative donor HCT from 2000-2010 and were reported to the Center for International Blood and Marrow Transplant Research (CIBMTR). Umbilical cord blood (UCB) (n
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42

Cutler, Corey, Shuli Li, Vincent T. Ho, et al. "Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation." Blood 109, no. 7 (2006): 3108–14. http://dx.doi.org/10.1182/blood-2006-09-046219.

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Abstract We assessed the combination of sirolimus and tacrolimus without methotrexate after myeloablative allogeneic stem cell transplantation from 53 matched related donors (MRDs) and 30 unrelated donors (URDs). All patients received cyclophosphamide and total body irradiation conditioning followed by transplantation of mobilized peripheral blood stem cells. The median time to neutrophil engraftment was 14 days. The median time to platelet engraftment was 12 days. No differences between MRD and URD cohorts was noted. The incidence of grade II-IV and III-IV acute graft-versus-host disease (GVH
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43

Kobayashi, Fumiya, Masahiro Toyama, and Itsuro Koizumi. "Potential resource competition between an invasive mammal and native birds: overlap in tree cavity preferences of feral raccoons and Ural owls." Biological Invasions 16, no. 7 (2013): 1453–64. http://dx.doi.org/10.1007/s10530-013-0583-z.

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Hahn, Theresa, Leah Preus, Philip L. McCarthy, et al. "Genome-Wide Association Study of Overall and Progression-Free Survival after HLA-Matched Unrelated Donor Blood and Marrow Transplantation (DISCOVeRY-BMT study)." Blood 126, no. 23 (2015): 397. http://dx.doi.org/10.1182/blood.v126.23.397.397.

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Abstract While survival outcomes after HLA-matched unrelated donor (URD) blood and marrow transplant (BMT) have significantly improved over the last 2 decades, about 40% of patients die of various causes before one-year post-URD BMT. We performed a genome-wide association study (GWAS) named DISCOVeRY-BMT (Determining the Influence of Susceptibility COnveying Variants Related to one-Year mortality after BMT) of overall (OS) and progression-free (PFS) survival in 3,532 patients treated for AML, ALL or MDS and reported to CIBMTR from 2000-2011 and their 8/8 HLA-matched URDs. Cohort 1 consisted of
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Nishiwaki, Satoshi, Koichi Miyamura, Kazuteru Ohashi, et al. "Impact of donor source on allogeneic stem cell transplantation for Philadelphia chromosome-negative acute lymphoblastic leukemia." Journal of Clinical Oncology 30, no. 15_suppl (2012): 6533. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.6533.

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6533 Background: Although allogeneic stem cell transplantation (allo-SCT) could improve the outcome of adult Philadelphia chromosome-negative acute lymphoblastic leukemia [Ph(-) ALL], the impact of the donor source, particularly the position of cord blood (CB) transplantation, is still uncertain. Methods: We retrospectively analyzed 1726 adult Ph(-) ALL patients transplanted at the first time between 1998 and 2009 with myeloablative preparative regimens who were registered in the Japan Society for Hematopoietic Cell Transplantation database. Two hundred and thirty-three received CB transplanta
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46

Oakes, Nathan, and Jennifer M. Medina McKeon. "Nonsurgical Management of Ulnar Collateral Ligament Injuries is Tentatively Successful in Overhead Athletes: A Critical Appraisal of Case Series." International Journal of Athletic Therapy and Training 25, no. 5 (2020): 213–20. http://dx.doi.org/10.1123/ijatt.2018-0132.

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Since its inception, surgical management of the ulnar collateral ligament (UCL) is fairly standard; however, the invasive, costly, and time-intensive nature of UCL surgery may be restrictive to some athletes. Electronic databases were searched starting from the year 2013 to September 2018. Extracted data included frequencies of (a) return to play (RTP); (b) return to same level of play (RTSP); (c) athlete’s position; (d) complete reconstitution of the UCL; and (e) the location of ligament rupture (proximal or distal). Proportions of success/failure for selected outcomes were calculated. Additi
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Wang, Zhenbin, Pengxiang Pei, Dongjie Bai, Shanshan Zhao, Xinyu Ma, and Weisheng Liu. "Multicolor luminescence and triple-mode emission of simple CaTiO3:Pr3+,Er3+ particles for advanced anti-counterfeiting." Inorganic Chemistry Frontiers 7, no. 13 (2020): 2506–14. http://dx.doi.org/10.1039/d0qi00462f.

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The multilevel anticounterfeiting QR code readily integrates the advantages of excitation wavelength-dependent PL emissions, a strong red afterglow and sensitive excitation power-dependent UCL emissions in one overall device.
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48

Howell, Jessica B., Eric N. Appelbaum, Michael F. Armstrong, Derek Chapman, and Kelley M. Dodson. "An Analysis of Risk Factors in Unilateral Versus Bilateral Hearing Loss." Ear, Nose & Throat Journal 98, no. 6 (2019): 330–33. http://dx.doi.org/10.1177/0145561319840578.

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A retrospective review of children with confirmed hearing loss identified through universal newborn hearing screening (UNHS) in Virginia from 2010 to 2014 was conducted in order to compare the incidence of Joint Committee on Infant Hearing (JCIH) risk factors in children with unilateral hearing loss (UHL) to bilateral hearing loss (BHL). Over the 5-year study period, 1004 children (0.20% of all births) developed a confirmed hearing loss, with 544 (51%) children having at least one JCIH risk factor. Overall, 18% of children with confirmed hearing loss initially passed UNHS. Of all children with
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Mrdalj, Stevan, Joseph Scazzero, and Vladan Jovanovic. "Effectiveness of the user interface driven system design using UML." Computer Science and Information Systems 1, no. 2 (2004): 153–72. http://dx.doi.org/10.2298/csis0402153m.

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The majority of research regarding the effectiveness of object-oriented analysis and design (OOAD) is focused on a comparison of object-oriented to traditional approaches that highlights their relative strengths and weaknesses. There has been less focus on improving OOAD on its own. The standardization of the Unified Modeling Language (UML) creates an opportunity to focus on improving the methods of developing UML diagrams. Design quality can be a litmus test for overall system quality. Practice has shown that designing user interfaces before domain modeling can be used on a systematic basis t
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Zhang, Heng, Xu Yang, Zhu Ying, Jing Liu, and Qun Liu. "Toxoplasma gondii UBL-UBA Shuttle Protein DSK2s Are Important for Parasite Intracellular Replication." International Journal of Molecular Sciences 22, no. 15 (2021): 7943. http://dx.doi.org/10.3390/ijms22157943.

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Toxoplasma gondii (T. gondii) is an important human and veterinary pathogen causing life-threatening disease in immunocompromised patients. The UBL-UBA shuttle protein family are important components of the ubiquitin–proteasome system. Here, we identified a novel UBL-UBA shuttle protein DSK2b that is charactered by an N-terminal ubiquitin-like domain (UBL) and a C-terminal ubiquitin-associated domain (UBA). DSK2b was localized in the cytoplasm and nucleus. The deletion of dsk2b did not affect the degradation of ubiquitinated proteins, parasite growth in vitro or virulence in mice. The double-g
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