Relevant bibliographies by topics / Urolithias

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Urolithias'

Author: Grafiati
Published: 4 June 2021
Last updated: 2 February 2022

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Journal articles on the topic "Urolithias"

1

Manu, M. A., B. Parliteanu, R. Manu, and I. Sinescu. "Consider the hyperparathyroidism in recurrent calcium urolithias." European Urology Supplements 14, no. 6 (October 2015): e1302. http://dx.doi.org/10.1016/s1569-9056(15)30339-0.

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Alzahrani, Abdulaziz Musa, Mohammed Razeeth Shait Mohammed, Raed Ahmed Alghamdi, Abrar Ahmad, Mazin A. Zamzami, Hani Choudhry, and Mohammad Imran Khan. "Urolithin A and B Alter Cellular Metabolism and Induce Metabolites Associated with Apoptosis in Leukemic Cells." International Journal of Molecular Sciences 22, no. 11 (May 22, 2021): 5465. http://dx.doi.org/10.3390/ijms22115465.

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Leukemia is persistently a significant cause of illness and mortality worldwide. Urolithins, metabolites of ellagic acid and ellagitannins produced by gut microbiota, showed better bioactive compounds liable for the health benefits exerted by ellagic acid and ellagitannins containing pomegranate and walnuts. Here, we assessed the potential antileukemic activities of both urolithin A and urolithin B. Results showed that both urolithin A and B significantly inhibited the proliferation of leukemic cell lines Jurkat and K562, among which urolithin A showed the more prominent antiproliferative capability. Further, urolithin treatment alters leukemic cell metabolism, as evidenced by increased metabolic rate and notable changes in glutamine metabolism, one-carbon metabolism, and lipid metabolism. Next, we evidenced that both urolithins equally promoted apoptosis in leukemic cell lines. Based on these observations, we concluded that both urolithin A and B alter leukemic cell metabolome, resulting in a halt of proliferation, followed by apoptosis. The data can be used for designing new combinational therapies to eradicate leukemic cells.
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Mendoza-López, Claudia I., Javier Del-Angel-Caraza, María A. Aké-Chiñas, Israel A. Quijano-Hernández, and Marco A. Barbosa-Mireles. "Epidemiology of feline urolithiasis in Mexico (2006–2017)." Journal of Feline Medicine and Surgery Open Reports 5, no. 2 (July 2019): 205511691988569. http://dx.doi.org/10.1177/2055116919885699.

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Objectives The objectives of this study were to identify the proportions of different types of uroliths, characterize the population of cats that present with urolithiasis and determine possible predisposing factors in a population of Mexican cats. Methods This study analyzed clinical specimens of feline urolithiasis submitted to our laboratory in the period from 2006 to 2017. The mineral composition of the uroliths was determined by qualitative and quantitative mineral analyses, performed by stereoscopic microscopy and infrared spectroscopy. Results In the population studied, 54.3% of all uroliths were calcium oxalate, followed by 32.1% struvite and 7.4% purine (urate and xanthine) uroliths, with other types accounting for 6.2% of submissions. The male:female ratio was 1.2:1. Calcium oxalate submissions were predominantly from males and struvite submissions were predominantly from females. The age of the cats with stone submissions ranged from 6 months to 17 years. In cats with calcium oxalate uroliths, 52.3% were aged 7 years or older. Cats with struvite uroliths were younger, with 65.4% younger than 6 years of age. Almost 90% of all submitted uroliths were from domestic shorthair cats. Conclusions and relevance This is the first epidemiologic study of urolithiasis in cats in Mexico. Age and sex predispositions to common uroliths were identified, as males aged ≥7 years primarily presented with calcium oxalate uroliths and females aged <6 years primarily presented struvite uroliths. Cases of urolithiasis of genetic origin, including xanthinuria and cystinuria, were also detected, in addition to silicate uroliths.
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Cisneros-Zevallos, Luis, Woo Young Bang, and Claudia Delgadillo-Puga. "Ellagic Acid and Urolithins A and B Differentially Regulate Fat Accumulation and Inflammation in 3T3-L1 Adipocytes While Not Affecting Adipogenesis and Insulin Sensitivity." International Journal of Molecular Sciences 21, no. 6 (March 18, 2020): 2086. http://dx.doi.org/10.3390/ijms21062086.

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Ellagic acid (EA) is a component of ellagitannins, present in crops such as pecans, walnuts, and many berries, which metabolized by the gut microbiota forms urolithins A, B, C, or D. In this study, ellagic acid, as well as urolithins A and B, were tested on 3T3-L1 preadipocytes for differentiation and lipid accumulation. In addition, inflammation was studied in mature adipocytes challenged with lipopolysaccharide (LPS). Results indicated that EA and urolithins A and B did not affect differentiation (adipogenesis) and only EA and urolithin A attenuated lipid accumulation (lipogenesis), which seemed to be through gene regulation of glucose transporter type 4 (GLUT4) and adiponectin. On the other hand, gene expression of cytokines and proteins associated with the inflammation process indicate that urolithins and EA differentially inhibit tumor necrosis factor alpha (TNFα), inducible nitric oxide synthase (iNOS), interleukin 6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1). Urolithins A and B were found to reduce nuclear levels of phosphorylated nuclear factor κB (p-NF-κB), whereas all treatments showed expression of nuclear phosphorylated protein kinase B (p-AKT) in challenged LPS cells when treated with insulin, indicating the fact that adipocytes remained insulin sensitive. In general, urolithin A is a compound able to reduce lipid accumulation, without affecting the protein expression of peroxisome proliferator-activated receptor-γ (PPARγ), CCAAT/enhancer binding protein-α (c/EBPα), and PPARα, whereas EA and urolithin B were found to enhance PPARγ and c/EBPα protein expressions as well as fatty acid (FA) oxidation, and differentially affected lipid accumulation.
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Mendoza-López, Claudia Iveth, Javier Del-Angel-Caraza, María Alejandra Aké-Chiñas, Israel Alejandro Quijano-Hernández, and Marco Antonio Barbosa-Mireles. "Canine Silica Urolithiasis in Mexico (2005–2018)." Veterinary Medicine International 2020 (October 21, 2020): 1–7. http://dx.doi.org/10.1155/2020/8883487.

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A higher frequency of canine silica urolithiasis is found in Mexico, unlike <1–8% in other countries. The causes and risk factors for this pathology are unknown. However, we consider the consumption of high amounts of silica from the solid diet or dissolved in water as the only hypothesis. This study aimed to identify the risk factors for silica urolithiasis in dogs from Mexico. A total of 1383 clinical cases of canine urolithiasis were included in this study; the uroliths were analyzed to determine their mineral composition by stereoscopic microscopy and infrared spectroscopy. Of these cases, 12.94% were considered pure silica uroliths; however, considering the mixed and compound uroliths, the frequency increased to 17.42%. Male dogs aged >6 years and large breeds, especially Labradors and Golden retrievers, were at significant risk for this disease. 98.88 % of the clinical cases studied were found in the central axis of the country, considering this finding as a possible geographical risk factor to be analyzed in another study.
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Cortés-Martín, Adrián, María Romo-Vaquero, Izaskun García-Mantrana, Ana Rodríguez-Varela, María Carmen Collado, Juan Carlos Espín, and María Victoria Selma. "Urolithin Metabotypes can Anticipate the Different Restoration of the Gut Microbiota and Anthropometric Profiles during the First Year Postpartum." Nutrients 11, no. 9 (September 3, 2019): 2079. http://dx.doi.org/10.3390/nu11092079.

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The metabolism of dietary polyphenols ellagitannins by the gut-microbiota allows the human stratification in urolithin metabotypes depending on the final urolithins produced. Metabotype-A only produces urolithin-A, metabotype-B yields urolithin-B and isourolithin-A in addition to urolithin-A, and metabotype 0 does not produce urolithins. Metabotype-A has been suggested to be ‘protective’, and metabotype-B dysbiotic-prone to cardiometabolic impairments. We analyzed the gut-microbiome of 40 healthy women and determined their metabotypes and enterotypes, and their associations with anthropometric and gut-microbial changes after 3 weeks, 4, 6, and 12 months postpartum. Metabotype-A was predominant in mothers who lost weight (≥2 kg) (75%) versus metabotype-B (54%). After delivery, the microbiota of metabotype-A mothers changed, unlike metabotype-B, which barely changed over 1 year. The metabotype-A discriminating bacteria correlated to the decrease of the women’s waist while some metabotype-B bacteria were inversely associated with a reduction of body mass index (BMI), waist, and waist-to-hip ratio. Metabotype-B was associated with a more robust and less modulating microbial and anthropometric profiles versus metabotype-A, in which these profiles were normalized through the 1-year follow-up postpartum. Consequently, urolithin metabotypes assessment could be a tool to anticipate the predisposition of women to normalize their anthropometric values and gut-microbiota, significantly altered during pregnancy and after childbirth.
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Nazarov, T. Kh, I. V. Rychkov, D. G. Lebedev, and K. E. Trubnikova. "COMPARATIVE ANALYSIS OF DATA FROM A DUAL-ENERGY COMPUTER TOMOGRAPH AND THE RESULTS OF A MINERALOGICAL RESEARCH OF URINARY STONES." Diagnostic radiology and radiotherapy, no. 2 (July 18, 2018): 54–58. http://dx.doi.org/10.22328/2079-5343-2018-9-2-54-58.

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Introduction. The idea of using dual-energy computed tomography (DECT) originated in the early development of computed tomography (CT). However, only recently, advances in radiation diagnosis have made it possible to use dual-energy CT for routine clinical use. We describes the characteristic features of dual-energy CT scanners, as well as the results of a study of 245 patients with urolithiasis, the identification of urinary stones in vivo and the subsequent comparative characteristics with mineralogical studies of uroliths. Purpose. Evaluate the possibility of using DECT in the diagnosis of urolithiasis with the determination of the chemical composition of urinary stones in vivo. Materials and methods. A group of patients (n=245) aged 18 to 84 years was examined. All patients with the established diagnosis-urolithiasis-were treated with DECT (Somatom Definition, Siemens, Forchheim, Germany) with data processing, then in-vitro infrared spectrometry (IR-Alpha-P spectrometer) to determine the true composition of the calcu lus. Results. After conducting the DECT and then ROC analysis and comparing the results with the IR-spectrometry data, it was established that stones with an average density of less than 500 HU according to DECT can be attributed to urate, with a uric acid content of more than 50% with a sensitivity of 91,1% (34 stones of 35) and specificity of 100% — the content of uric acid is also determined in polymineral calculi with a content of less than 50%. The knowledge gained on the composition and structure of the stone in vivo can subsequently be used in pathogenetic treatment and prevention of complications in patients with urolithiasis, and influence the choice of the tactics of removing the uroliths. Conclusions. The obtained results give the right to apply DECT in the diagnosis of urolithiasis, and with high sensitivity to identify urate stones in vivo, thereby influencing the choice of the tactics of removal of uroliths and pathogenetic treatment, as well as the prevention of complications in patients with urolithiasis.
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Pancini, Hadrian. "A DIETA COMO UM FATOR DE PREVENÇÃO E TRATAMENTO DE UROLITÍASE EM CÃES E GATOS." Multi-Science Research 03, no. 01 (August 1, 2020): 71–78. http://dx.doi.org/10.47621/m-sr.2020.v.3.n.1.78-036.

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The urolithiasis is one of the most motives of dogs and cats complaints attended with urinary affections. Objective of the work was to show the importance of the diet with a factor of prevention and treatment of urolithiasis in dogs and cats. The research technique used was bibliographic research. The formation of kidney crystals and stones with causes as decreased urination associated with urine supersaturation, being able to be related to dietary factors. Amoung the main existings uroliths, stand out those made of struvite and calcium oxalate. The nutrition can be related to the formation, prevention and treatment of urolithiasis, mainly in relation to the pH control and acid/basic balance present in industrialized rations. Given the above, the research presents information that shows the interference of nutrition in dogs and cats with urolithiasis. Keywords: Urolithiasis. Struvite. Calcium oxalate. Diet.
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Singh, Rajbir, Sandeep Chandrashekharappa, Praveen Kumar Vemula, Bodduluri Haribabu, and Venkatakrishna Rao Jala. "Microbial Metabolite Urolithin B Inhibits Recombinant Human Monoamine Oxidase A Enzyme." Metabolites 10, no. 6 (June 19, 2020): 258. http://dx.doi.org/10.3390/metabo10060258.

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Urolithins are gut microbial metabolites derived from ellagitannins (ET) and ellagic acid (EA), and shown to exhibit anticancer, anti-inflammatory, anti-microbial, anti-glycative and anti-oxidant activities. Similarly, the parent molecules, ET and EA are reported for their neuroprotection and antidepressant activities. Due to the poor bioavailability of ET and EA, the in vivo functional activities cannot be attributed exclusively to these compounds. Elevated monoamine oxidase (MAO) activities are responsible for the inactivation of monoamine neurotransmitters in neurological disorders, such as depression and Parkinson’s disease. In this study, we examined the inhibitory effects of urolithins (A, B and C) and EA on MAO activity using recombinant human MAO-A and MAO-B enzymes. Urolithin B was found to be a better MAO-A enzyme inhibitor among the tested urolithins and EA with an IC50 value of 0.88 µM, and displaying a mixed mode of inhibition. However, all tested compounds exhibited higher IC50 (>100 µM) for MAO-B enzyme.
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Serakides, R., A. F. C. Ribeiro, C. M. Silva, R. L. Santos, V. A. Nunes, and E. F. Nascimento. "Proliferative and inflammatory changes in the urinary bladder of female rats naturally infected with Trichosomoides crassicauda: report of 48 cases." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 53, no. 2 (April 2001): 1–5. http://dx.doi.org/10.1590/s0102-09352001000200012.

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The objective of this report was to describe the pathological changes in the urinary bladder of female rats naturally infected with Trichosomoides crassicauda. Forty eight 5 to 8 months of age female Wistar rats were studied. At necropsy uroliths were detected in seven animals (14.6%). Among the bladders that contained the parasite only three (6.3%) did not show any significant histological change and were considered normal, but on the contrary, three (6.3%) did contain papillomas and uroliths, four (8.3%) had uroliths associated with epithelial hyperplasia ranging from moderate to severe, and the remaining (79.2%) showed variable degrees of epithelial hyperplasia and inflammation without urolithiasis. It cannot be concluded whether irritation of the epithelium by the parasite itself plays a role in the formation of papillomas. However, the absence of papillomas in animals without uroliths suggests a positive relationship between uroliths and papillomas.
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Dissertations / Theses on the topic "Urolithias"

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Mayo, M. E. "Interaction of laser radiation with urinary calculi." Thesis, Department of Applied Science, Security and Resillience, 2009. http://hdl.handle.net/1826/4013.

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Urolithias, calculus formation in the urinary system, affects 5 – 10% of the population and is a painful and recurrent medical condition. A common approach in the treatment of calculi is the use of laser radiation, a procedure known as laser lithotripsy, however, the technique has not yet been fully optimised. This research examines the experimental parameters relevant to the interactions of the variable microsecond pulsed holmium laser (λ = 2.12 μm, τp = 120 – 800 μs, I ~ 3 MW cm-2) and the Q-switched neodymium laser (λ = 1064 nm, τp = 6 ns, I ~ 90 GW cm-2) with calculi. The laser-calculus interaction was investigated from two perspectives: actions that lead to calculus fragmentation through the formation of shockwave and plasma, and the prospect of material analysis of calculi by laser induced breakdown spectroscopy (LIBS) to reveal elemental composition. This work is expected to contribute to improved scientific understanding and development of laser lithotripsy. The results support the general model of thermal and plasma processes leading to vaporization and pressure pulses. Nd:YAG laser interaction processes were found to be plasma-mediated and shockwave pressure (~ 12 MPa) dependent on plasma and strongly influenced by metal ions. Ho:YAG laser-induced shockwaves (~ 50 MPa) were found to be due to direct vaporisation of water and dependent on laser pulse duration. The characteristics of the pressure pulse waveforms were found to be different, and the efficiency and repeatability of shockwave and the nature of the dependencies for the lasers suggest different bubble dynamics. For the Nd:YAG laser, LIBS has been demonstrated as a potential tool for in situ analysis of calculus composition and has been used for the identification of major and trace quantities of calcium, magnesium, sodium, potassium, strontium, chromium, iron, copper, lead and other elements.
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Mayo, Michael E. "Interaction of laser radiation with urinary calculi." Thesis, Cranfield University, 2009. http://dspace.lib.cranfield.ac.uk/handle/1826/4013.

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Urolithias, calculus formation in the urinary system, affects 5 – 10% of the population and is a painful and recurrent medical condition. A common approach in the treatment of calculi is the use of laser radiation, a procedure known as laser lithotripsy, however, the technique has not yet been fully optimised. This research examines the experimental parameters relevant to the interactions of the variable microsecond pulsed holmium laser (λ = 2.12 μm, τp = 120 – 800 μs, I ~ 3 MW cm-2) and the Q-switched neodymium laser (λ = 1064 nm, τp = 6 ns, I ~ 90 GW cm-2) with calculi. The laser-calculus interaction was investigated from two perspectives: actions that lead to calculus fragmentation through the formation of shockwave and plasma, and the prospect of material analysis of calculi by laser induced breakdown spectroscopy (LIBS) to reveal elemental composition. This work is expected to contribute to improved scientific understanding and development of laser lithotripsy. The results support the general model of thermal and plasma processes leading to vaporization and pressure pulses. Nd:YAG laser interaction processes were found to be plasma-mediated and shockwave pressure (~ 12 MPa) dependent on plasma and strongly influenced by metal ions. Ho:YAG laser-induced shockwaves (~ 50 MPa) were found to be due to direct vaporisation of water and dependent on laser pulse duration. The characteristics of the pressure pulse waveforms were found to be different, and the efficiency and repeatability of shockwave and the nature of the dependencies for the lasers suggest different bubble dynamics. For the Nd:YAG laser, LIBS has been demonstrated as a potential tool for in situ analysis of calculus composition and has been used for the identification of major and trace quantities of calcium, magnesium, sodium, potassium, strontium, chromium, iron, copper, lead and other elements.
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Bayle, Morgane. "Potentiel antidiabétique de métabolites de polyphénols : les urolithines." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT018.

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Notre travail de thèse avait pour objet l’étude du potentiel anti-diabétique des urolithines A, B, C et D, métabolites de polyphénols formés par le microbiote colique à partir des tanins de l’acide ellagique (présents notamment dans la grenade et les noix).La première partie, bibliographique, constitue un rappel :• de la régulation de l’équilibre glycémique et le rôle de la sécrétion d’insuline dans cette régulation ; •de l ‘épidémiologie et la physiopathologie du diabète type 2 (DT2) ; •des polyphénols et leurs métabolites, ainsi que de leurs effets antidiabétiques potentiels.La seconde partie décrit les effets des urolithines sur différents modèles expérimentaux : •Sur un modèle de cellules β insulino-sécrétrices (lignée INS-1), les urolithines induisent une amplification concentration-dépendante de la sécrétion d’insuline induite par le glucose, mais également par d’autres sécrétagogues comme un analogue du GLP-1 ou une sulfonylurée (médicaments utilisés dans le diabète). Les urolithines préviennent également l’altération sécrétoire induite par un stress oxydant. •L’effet insulino-sécrétoire des urolithines a été confirmé sur îlots de Langerhans isolés. •L’urolithine C étant apparu comme le composé le plus prometteur, nous avons poursuivi la caractérisation de son activité sur un modèle ex vivo mimant la situation physiologique, le pancréas isolé perfusé. Alors que l’effet sécrétoire de l’urolithine C n’apparaît pas en présence de 5mM de glucose, l’urolithine C (20µM) a stimulé la sécrétion d’insuline dans des conditions de stimulation modérée de la sécrétion d’insuline par le glucose (8.3mM). Cet effet est strictement dépendant du glucose, la sécrétion d’insuline retournant immédiatement à son niveau basal lors du passage de 8,3 à 5mM de glucose en présence d’urolithine C. •Des études de pharmacocinétique ont permis de mettre au point une méthodologie de dosage plasmatique de l’urolithine C dans le plasma de rat par chromatographie liquide / ionisation electrospray /spectrographie de masse en tandem. Cette méthodologie a été appliquée à une première étude pharmacocinétique chez le rat après injection de 10mg/kg d’urolithine C par voie intra-péritonéale. Cette étude montre notamment que le profil pharmacocinétique suit un modèle à 3 compartiments et suggère un stockage tissulaire du composé.D’autres résultats (confidentiels) ne peuvent être évoqués dans ce résumé mais confirment l’intérêt potentiel de l’urolithine C dans le traitement du diabète de type 2 en tant que médicament insulinotrope dépendant du glucose
The objective of our thesis was to study the anti-diabetic potential of metabolites of ellagic acid tanins, present notably in pomegranate and nuts, that are formed by the colon microbiote. The metabolites are urolithins A, B, C and D.The first part of thesis is bibliographic and reviews: •The control of glycemic plasma levels, and in particular the role of insulin secretion in this process; • The pathophysiology of Type 2 Diabetes (T2D); •The various polyphenols and their metabolites, along with their potential anti-diabetic activity.The second part describes the effects of urolithins on various experimental models: •On a model of insulin secreting beta cells (the INS-1cell line), urolithins concentration-dependently amplified insulin secretion induced by glucose, but also by insulinotropic drugs used in the treatment of T2D such as a GLP-1 analogue or a sulfonylurea. In addition, urolithins were able to induce insulin secretion on cells rendered unresponsive to glucose by oxidative stress. • The insulinotropic effect of urolithins was also confirmed on isolated rat islets of Langerhans. •As urolithin C appeared to be the most promising antidiabetic compound, we further characterized its activity on an ex vivo model mimicking the physiological situation, the isolated infused pancreas. While urolithin C (20µM) had no effect in the presence of 5 mM glucose concentration, it amplified the stimulation of insulin secretion in the presence of 8.3mM glucose. The effect of urolithin C was also strictly glucose-dependent, as insulin secretion immediately returned to basal level when glucose concentration was switched from 8.3 to 5mM glucose in the presence of urolithin C. •We also conducted studies aiming at designing a validated methodology for rat plasma urolithin C determination using a liquid chromatography-electrospray ionization-tandem mass spectrometry method. The applicability of this assay was demonstrated in a preclinical pharmacokinetic study carried out in rats receiving intraperitoneal administration of urolithin C (10mg/kg). We found that the urolithin C followed a three-compartment model, suggesting a long-term tissue storage of urolithin C.Some other (confidential) results, not described in this abstract, confirmed urolithin C as a potential glucose-dependent insulinotropic treatment for type 2 diabetes
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Rodrigues, Maria Cardoso Tavares. "Estudo retrospetivo da litíase urinária em cães e gatos." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2021. http://hdl.handle.net/10400.5/21115.

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Dissertação de Mestrado Integrado em Medicina Veterinária
A urolitíase está associada, com cada vez maior frequência, ao trato urinário de cães e gatos. Os cálculos urinários, vulgarmente intitulados de “pedras”, vão-se formando no trato urinário por acumulação e congregação de cristais existentes na urina (a estruvite e o oxalato de cálcio são os mais frequentes). A formação destes urólitos está frequentemente relacionada com a ingestão insuficiente de água, dietas inadequadas (por exemplo, rações de baixa qualidade) e/ou fatores genéticos. Os urólitos podem ser simples ou podem ter composição mista ou composta. Alguns cálculos são passíveis de ser dissolvidos através da mudança do pH urinário (essencialmente por maneio alimentar), enquanto outros não. São encontrados em qualquer parte do trato urinário e, quando localizados nos rins, o termo nefrolitíase é mais utilizado por ser mais específico, em detrimento de urolitíase, que é mais geral. Os urólitos podem, por vezes, originar situações críticas, como um quadro obstrutivo. Esta é uma urgência médico/cirúrgica e deve ser tratada o mais depressa possível, caso contrário, pode ter um desfecho fatal. A profilaxia médica baseia-se na diminuição da saturação urinária dos cristais que formam os cálculos. O presente estudo retrospetivo analisou os dados clínicos de três gatos (um macho e duas fêmeas) e duas cadelas com diagnóstico de urolitíase, acompanhados no Hospital Veterinário de Alvalade. O exame complementar mais realizado foi a radiografia. O sinal clínico mais frequente foi a prostração, presente em quatro dos cinco casos clínicos. Foram removidos os cistólitos de três dos animais por cistotomia e foi posteriormente avaliada a respetiva composição em apenas dois dos casos, sendo um fator limitante para o sucesso do tratamento. Num dos casos o urólito era composto apenas por um mineral (oxalato de cálcio mono-hidratado) e no outro a composição era mista (20% de fosfato de cálcio e 80% de estruvite). Após diagnóstico de litíase, todos os animais fizeram mudança alimentar para uma ração adequada. O tamanho reduzido da amostra impossibilitou a obtenção de resultados significativos. O tratamento pode representar um desafio, pois, muitas vezes, é necessário ajustar toda a abordagem terapêutica e dietética a cada caso individual, tendo em conta que muitas vezes existem alterações ou doenças subjacentes (nomeadamente doença renal) e/ou restrições monetárias. Nesta revisão, foi ainda realçada a importância do papel do detentor no sucesso do tratamento e a necessidade de uma adesão rigorosa ao protocolo instituído pelo Médico Veterinário.
ABSTRACT - Urolithiasis is associated, with increasing frequency, to the urinary tract of dogs and cats. Calculi, commonly known as “stones”, are formed in the urinary tract by accumulation and congregation of crystals present in urine (struvite and calcium oxalate are the most frequent). The formation of these uroliths is often related to an insufficient water intake, inadequate diet (e.g. poor-quality rations) and/or genetic factors. Uroliths can be simple or have mixed or compound composition. Some calculi are liable to be dissolved by changing the urinary’s pH (essentially through food management), while others are not. They are found anywhere in the urinary tract and, when located in the kidneys, the term nephrolithiasis is more used as it is more specific, as an alternative to urolithiasis, which is the general term. Uroliths can sometimes lead to critical situations, such as an obstructive condition. This is a medical/surgical emergency and should be treated as soon as possible, otherwise it may have a fatal outcome. Medical prophylaxis is based on decreasing the urine saturation of the crystals that form the calculi. The present retrospective study analyzed the clinical data of three cats (one male and two females) and two female dogs, diagnosed with urolithiasis from Hospital Veterinário de Alvalade. The most performed complementary exam was radiography. The most frequent clinical sign was prostration, present in four of the five clinical cases. The cystoliths of three animals were removed by cystotomy, and the respective composition was subsequently evaluated in only two of the cases, being a limiting factor for the success of the treatment. In one case the urolith was composed of a single mineral (calcium oxalate monohydrate) and in the other the composition was mixed (20% calcium phosphate and 80% struvite). After diagnosing lithiasis, all animals changed their diet to an adequate one. The small sample size proved limiting to obtain significant results. Treatment can be challenging, as it is often necessary to adjust the entire therapeutic and dietary approach to each individual case, taking into account that there are often underlying changes or illness (namely kidney disease) and/or monetary restrictions. In this review, the importance of the tutor’s role in the success of the treatment and the need for strict adherence to the protocol established by the Veterinarian, was also highlighted.
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Garcia, Munoz Maria-Cristina. "Bioconversion des ellagitannins de la mûre tropicale de montagne (Rubus Adenotrichos) et relation avec l'écologie du microbiome intestinal." Thesis, Montpellier, SupAgro, 2013. http://www.theses.fr/2013NSAM0031/document.

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La consommation d'aliments riches en ellagitannins (ETs) pourrait être associée principalement à la prévention des maladies cardiovasculaires et la régulation des cancers hormono-dépendants. Néanmoins, les ETs ne sont pas biodisponibles en tant que tel et, après avoir été partiellement transformés en acide ellagique (EA) dans le tractus gastro-intestinal (GI) supérieur, ils sont métabolisés dans le côlon par la flore intestinale en urolithines, un groupe de molécules plus biodisponibles et bioactives qui peuvent persister jusqu'à 4 jours à des concentrations relativement élevées dans le plasma et l'urine. La variabilité de l'excrétion des urolithines dans l'urine est importante et à partir d'un échantillon de population de 26 volontaires sains, trois groupes principaux d'individus ont pu être distingués : "faible ou non-excréteur d'urolithin », « Excréteur prédominant d'UA et dérivés» et « Excréteur prédominant d'UB et dérivés»". Ces groupes ont également été observés en considérant la cinétique totale d'excrétion sur une période de 4 jours après ingestion du jus et à des périodes différentes tout au long d'une année. Bien que les variabilités inter-et intra-individuelles soient relativement élevées, les individus conservent leur statut au cours des différentes périodes d'intervention même en modifiant les quantités d'ETs ingérées. L'analyse par UPLC-PDA/ESI-Q-TOF/MS2 a permis d'attribuer hypothétiquement une identité à 15 autres métabolites d'ETs dans l'urine, mais le profilage métabolomique n'a pas permis de discriminer d'autres composés exceptés les dérivés d'UA ou d'UB. La fermentation in-vitro des ETs et EA, par les matières fécales a montré une voie métabolique spécifique qui débouche sur la production d'UA. Néanmoins, les métabolites excrétés in vivo sont beaucoup plus complexes ce qui met en évidence de fortes interactions entre le système excréteur de l'hôte et la composition du microbiote intestinal. La recirculation hépatique suivie par une re-conversion des métabolites de phase II dans le côlon permettrait d'expliquer l'excrétion d'UB chez certains volontaires. L'écologie spécifique de la flore intestinale évaluée par la méthode des empreintes PCR-DGGE a permis d'identifier quelques microorganismes associés à une plus grande capacité de bioconversion des ETs en urolithins
Consumption of dietary ellagitannins (ETs) could be associated mainly with prevention of cardiovascular diseases and regulation of hormone-dependent cancers. Nonetheless, ETs are not bioavailable as such; therefore, after being partially converted into ellagic acid (EA) in the upper gastrointestinal (GI) tract, they undergo sequential bioconversion in the colon by gut microbiota into urolithins, a more bioavailable and bioactive group of molecules that persist up to 4 days at relatively high concentrations in urine. Variability of urolithin excretion in urine is high and three main groups, “no or low urolithin excreters,” “predominantly UA derivatives excreters” and “predominantly UB derivatives excreters,” were observed on a cohort of 26 healthy volunteers. These categories were also unambiguously observed following the total excretion of main ETs' metabolites over a 4 day period after ingesting one shot of juice, and at different periods of time along one year. Although relatively high inter- and intra-individual variabilities were observed, individuals preserved their status during various intervention periods with different amounts of ETs ingested. UPLC-PDA and ESI-Q-TOF/MS1 and MS2 allowed the tentative assignment of an identity to 15 other ETs metabolites in urine, but this profiling did not allow the discrimination of any other compounds aside from UA or UB derivatives. In-vitro fermentation of ETs and EA with fecal stools showed a specific metabolic pathway ending in the production of UA. Nonetheless, metabolites excreted in-vivo are much more complex, highlighting strong interactions between host excretory system and composition of gut microbiota. Hepatic recirculation and additional bioconversion of Phase II metabolites in the colon may explain predominant excretion of UB in some volunteers. Microbiota ecology assessed by PCR-Denaturing Gradient Gel Electrophoresis (DGGE) fingerprint method allowed the association of some microorganism species to higher capacity of bioconversion of dietary ETs into urolithins.Key words: Ellagitannins, blackberry, urolithin, colonic metabolites, ETs degradation patterns, gut microbiota, gastrointestinal tract
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Sickinger, Marlene [Verfasser]. "Urolithiasis bei Schafböcken / Marlene Sickinger." Gießen : Universitätsbibliothek, 2020. http://d-nb.info/1209140543/34.

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Hilburger, Michaela. "Holmium YAG Laserlithotrypsie in der Behandlung der Urolithiasis." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-116955.

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Frenk, Marina. "Epidemiologische und laborexperimentelle Untersuchungen zur Urolithiasis bei Katzen." Diss., [S.l.] : [s.n.], 2006. http://edoc.ub.uni-muenchen.de/archive/00005970.

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Schoeler, Stefan. "Kurz- und Langzeitergebnisse nach ureterorenoskopischer Therapie bei Urolithiasis." [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964211335.

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Bonner, Michael Charles. "Clinical implications of infection, encrustation and fracture of polyurethane-based ureteral stents." Thesis, Queen's University Belfast, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.295365.

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Books on the topic "Urolithias"

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International Symposium on Urolithiasis (6th 1988 Vancouver, B.C.). Urolithiasis. New York: Plenum Press, 1989.

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Walker, Valerie R., Roger A. L. Sutton, E. C. Bert Cameron, Charles Y. C. Pak, and William G. Robertson, eds. Urolithiasis. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4899-0873-5.

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Talati, Jamsheer J., Hans-Goran Tiselius, David M. Albala, and ZHANGQUN YE, eds. Urolithiasis. London: Springer London, 2012. http://dx.doi.org/10.1007/978-1-4471-4387-1.

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Schneider, Hans-Joachim, ed. Urolithiasis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-70712-4.

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Moran, Michael E. Urolithiasis. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-8196-6.

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Knoll, Thomas, and Arkadiusz Miernik, eds. Urolithiasis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62454-8.

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International Symposium on Urolithiasis (8th 1996 Dallas, TX). Urolithiasis: 1996. Dallas TX: Millet the Printer, inc., 1996.

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Ryall, Rosemary, Renze Bais, Villis R. Marshall, Allan M. Rofe, Lynwood H. Smith, and Valerie R. Walker, eds. Urolithiasis 2. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2556-1.

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Akimoto, Masao, Eiji Higashihara, Hiromi Kumon, Zenjiro Masaki, and Seiichi Orikasa, eds. Treatment of Urolithiasis. Tokyo: Springer Japan, 2001. http://dx.doi.org/10.1007/978-4-431-68517-3.

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Schneider, Hans-Joachim, ed. Urolithiasis: Etiology · Diagnosis. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70579-3.

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Book chapters on the topic "Urolithias"

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Miller, K., and F. Eisenberger. "Urolithiasis." In Urologie für die Praxis, 90–99. Munich: J.F. Bergmann-Verlag, 1986. http://dx.doi.org/10.1007/978-3-642-97808-1_5.

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Sultan, Sajid, Sadaf Aba Umer, and Bashir Ahmed. "Urolithiasis." In Practical Pediatric Urology, 377–403. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-54020-3_18.

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Zonneveld, W. C. G. "Urolithiasis." In Het urologie formularium, 158–67. Houten: Bohn Stafleu van Loghum, 2011. http://dx.doi.org/10.1007/978-90-313-8863-9_16.

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Knoll, T. "Urolithiasis." In Facharztwissen Urologie, 171–96. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-01626-4_14.

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Mshelbwala, Philip M., Jessica Ng, and Adam B. Hittelman. "Urolithiasis." In Pediatric Surgery, 1019–26. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41724-6_97.

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Zonneveld, W. C. G. "Urolithiasis." In Het urologie formularium, 183–93. Houten: Bohn Stafleu van Loghum, 2015. http://dx.doi.org/10.1007/978-90-368-0628-2_16.

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Buchta, Mark, Dirk W. Höper, and Andreas Sönnichsen. "Urolithiasis." In Das Zweite StEx, 919–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18569-4_245.

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Kuntz, Nicholas J., and Michael E. Lipkin. "Urolithiasis." In Urology at a Glance, 213–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54859-8_42.

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Johnston, Thomas, James Armitage, and Oliver Wiseman. "Urolithiasis." In MCQs for the FRCS(Urol) and Postgraduate Urology Examinations, 169–93. First edition. | Boca Raton : CRC Press, 2020.: CRC Press, 2020. http://dx.doi.org/10.1201/9780429021633-16.

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Knoll, T. "Urolithiasis." In Facharztwissen Urologie, 121–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-45739-9_14.

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Conference papers on the topic "Urolithias"

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Moran, Michael E., Katherine Ruzhansky, James C. Williams, Andrew P. Evan, James E. Lingeman, and James A. McAteer. "Frederik Ruysch’s Fascination With Urolithiasis." In RENAL STONE DISEASE 2: 2nd International Urolithiasis Research Symposium. AIP, 2008. http://dx.doi.org/10.1063/1.2998042.

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Popescu, Sofia. "DIETARY FACTORS IN CALCIUM OXALATE UROLITHIASIS." In 13th SGEM GeoConference NANO, BIO AND GREEN � TECHNOLOGIES FOR A SUSTAINABLE FUTURE. Stef92 Technology, 2013. http://dx.doi.org/10.5593/sgem2013/bf6/s25.008.

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Stark, Christopher M., Gregory Gorman, and Cade Nylund. "Pediatric Inflammatory Bowel Disease and Urolithiasis." In Selection of Abstracts From NCE 2016. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/peds.141.1_meetingabstract.756.

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Jones, Jeffrey A., Ashot Sargsyan, Robert Pietryzk, C. Sams, Phillip Stepaniak, P. Whitson, James C. Williams, Andrew P. Evan, James E. Lingeman, and James A. McAteer. "Urolithiasis and Genitourinary Systems Issues for Spaceflight." In RENAL STONE DISEASE 2: 2nd International Urolithiasis Research Symposium. AIP, 2008. http://dx.doi.org/10.1063/1.2998040.

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Stanisławska, I., J. Piwowarski, S. Granica, and A. Kiss. "Urolithins, gut microbiota metabolites of ellagitannins, in prostate cancer chemoprevention." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608066.

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Nisa, Ulfatun, Peristiwan Ridha Widhi Astana, Saryanto, Tyas Friska Dewi, and Enggar Wijayanti. "The Renal Protective Potential Effect of Infusion of Anti-urolithiasis Formula in Urolithiasis Patients: A Randomized Clinical Study." In 1’s t Jenderal Soedirman International Medical Conference (JIMC) in conjunction with the Annual Scientific Meeting (Temilnas) Consortium of Biomedical Science Indonesia (KIBI ). SCITEPRESS - Science and Technology Publications, 2020. http://dx.doi.org/10.5220/0010488300910097.

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Aliev, M. M. ogly, and E. A. ogly Museibov. "Treatment of urolithiasis in patients with diabetes mellitus." In Scientific dialogue: Medical issues. ЦНК МОАН, 2019. http://dx.doi.org/10.18411/spc-15-05-2019-02.

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Koul, Hari K., Sweaty Koul, James C. Williams, Andrew P. Evan, James E. Lingeman, and James A. McAteer. "Molecular Basis of Urolithiasis: Role of Crystal Retention." In RENAL STONE DISEASE 2: 2nd International Urolithiasis Research Symposium. AIP, 2008. http://dx.doi.org/10.1063/1.2998006.

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Adams, Larry G., and Jody P. Lulich. "Laser lithotripsy for removal of uroliths in dogs." In Biomedical Optics 2006, edited by Nikiforos Kollias, Haishan Zeng, Bernard Choi, Reza S. Malek, Brian J. Wong, Justus F. R. Ilgner, Eugene A. Trowers, et al. SPIE, 2006. http://dx.doi.org/10.1117/12.646820.

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Chung, Wen-Yaw, Roozbeh F. Ramezani, Chean-Yeh Cheng, Chien-Hua Wu, Tzong Rong Ger, Nathan S. K. Hsiung, Szu-Han Wang, and Vincent F. S. Tsai. "Dual Key-Parameter Sensing System Development for Urolithiasis Recurrence Prevention." In ICBET 2020: 2020 10th International Conference on Biomedical Engineering and Technology. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3397391.3397417.

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Reports on the topic "Urolithias"

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Wu, Qiao, Rui Liang, Yi Huang, Chunlin Tan, Tao Wu, and Tielong Tang. Meta-analysis of the association between new onset hypertension and renal urolithiasis after extracorporeal shock wave lithotripsy therapy. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2020. http://dx.doi.org/10.37766/inplasy2020.9.0045.

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