Academic literature on the topic 'Urotensin II'

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Journal articles on the topic "Urotensin II"

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Giuliani, Luisa, Livia Lenzini, Michele Antonello, et al. "Expression and Functional Role of Urotensin-II and Its Receptor in the Adrenal Cortex and Medulla: Novel Insights for the Pathophysiology of Primary Aldosteronism." Journal of Clinical Endocrinology & Metabolism 94, no. 2 (2009): 684–90. http://dx.doi.org/10.1210/jc.2008-1131.

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Abstract Context: The involvement of urotensin II, a vasoactive peptide acting via the G protein-coupled urotensin II receptor, in arterial hypertension remains contentious. Objective: We investigated the expression of urotensin II and urotensin II receptor in adrenocortical and adrenomedullary tumors and the functional effects of urotensin II receptor activation. Design: The expression of urotensin II and urotensin II receptor was measured by real time RT-PCR in aldosterone-producing adenoma (n = 22) and pheochromocytoma (n = 10), using histologically normal adrenocortical (n = 6) and normal
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Desai, Nirav, Jameel Sajjad, and William H. Frishman. "Urotensin II." Cardiology in Review 16, no. 3 (2008): 142–53. http://dx.doi.org/10.1097/crd.0b013e31815c8048.

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Giebing, G., M. Tölle, S. Schmidt, A. Oksche, W. Zidek, and M. Van Der Giet. "UROTENSIN II-RECEPTORS SHOW RAPID DESENSITIZATION AFTER STIMULATION WITH UROTENSIN II." Journal of Hypertension 22, Suppl. 2 (2004): S48. http://dx.doi.org/10.1097/00004872-200406002-00161.

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Dubessy, Christophe, Dorthe Cartier, Benoît Lectez, et al. "Characterization of urotensin II, distribution of urotensin II, urotensin II-related peptide and UT receptor mRNAs in mouse: evidence of urotensin II at the neuromuscular junction." Journal of Neurochemistry 107, no. 2 (2008): 361–74. http://dx.doi.org/10.1111/j.1471-4159.2008.05624.x.

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Lafta, Israa A., Nahla A. AL-Bakri, and Wasan A. Abdulhameed. "Expression of Urotensin II of Human Placental Tissues and in Serum in Gestational Diabetic Mellitus in Iraqi Woman." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 01 (2022): 70–73. http://dx.doi.org/10.25258/ijddt.12.1.13.

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The placenta is an organ between the mother and fetus necessary for fetal growth and development. Gestational diabetes mellitus (DM) is the most frequent metabolic condition detected during pregnancy. It is characterized as hyperglycemia of various severity with onset or first detection during pregnancy that does not clearly describe any form of preexisting diabetes. Urotensin II (UII), a pluripotent vasoactive peptide, is important in developing insulin resistance. This study aimed to determine the level of Urotensin II(UII) in placenta and in the serum of diabetic and nondiabetic women. Meth
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Itoh, H., and K. Lederis. "Relationship of urotensin I induced vasodilatory action in rat thoracic aorta to Ca2+ regulation." Canadian Journal of Physiology and Pharmacology 65, no. 3 (1987): 298–302. http://dx.doi.org/10.1139/y87-052.

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The relaxant effects of the synthetic fish neuropeptide urotensin I were examined in helical strips of rat aorta. In K+-depolarized aorta strips, urotensin I and verapamil competitively inhibited Ca2+-induced contractions. Urotensin I relaxed, in a concentration-dependent manner, the contraction produced by the Ca2+ ionophore A23187, whereas verapamil had no effect on this contraction, even at a concentration of 10−5 M. In the absence and presence of extracellular Ca2+, urotensin I inhibited both components of the contractions elicited by norepinephrine or urotensin II, another fish neuropepti
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Strack, Martin, Étienne Billard, David Chatenet, and William D. Lubell. "Urotensin core mimics that modulate the biological activity of urotensin-II related peptide but not urotensin-II." Bioorganic & Medicinal Chemistry Letters 27, no. 15 (2017): 3412–16. http://dx.doi.org/10.1016/j.bmcl.2017.05.088.

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Carotenuto, A., P. Grieco, P. Rovero, and E. Novellino. "Urotensin-II Receptor Antagonists." Current Medicinal Chemistry 13, no. 3 (2006): 267–75. http://dx.doi.org/10.2174/092986706775476061.

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Loirand, Gervaise, Malvyne Rolli-Derkinderen, and Pierre Pacaud. "Urotensin II and atherosclerosis." Peptides 29, no. 5 (2008): 778–82. http://dx.doi.org/10.1016/j.peptides.2007.08.024.

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Hazon, N., C. Bjenning, and J. M. Conlon. "Cardiovascular actions of dogfish urotensin II in the dogfish Scyliorhinus canicula." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 265, no. 3 (1993): R573—R576. http://dx.doi.org/10.1152/ajpregu.1993.265.3.r573.

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Bolus injections of synthetic dogfish urotensin II (0.1-1.0 nmol) into the celiac artery of the conscious dogfish Scyliorhinus canicula (n = 8) resulted in sustained and dose-dependent increases in arterial blood pressure and pulse pressure. A maximum rise in mean arterial pressure of 10.5 +/- 1.2 mmHg (equivalent to 38.6 +/- 4.2% over mean basal values) and a maximum increase in pulse pressure of 3.9 +/- 0.8 mmHg was elicited by injection of 0.5 nmol of peptide. In comparison, a bolus injection of epinephrine (5 nmol) elicited a rise of 24.8 +/- 3.3% in mean arterial pressure. Bolus injection
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Dissertations / Theses on the topic "Urotensin II"

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Batuwangala, Madura Suharshana. "Human urotensin-II receptor desensitisation." Thesis, University of Leicester, 2009. http://hdl.handle.net/2381/7846.

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Human Urotensin-II (U-II) is a cyclic undecapeptide that binds to the U-II receptor UT. The desensitisation mechanisms of the UT receptor (G_{q/11} coupled GPCR) are not well defined and hampered by (1) lack of native (in-vitro) models; (2) paucity of ligands, especially non-peptides and (3) irreversible binding of U-II. There are some limited studies using rat aorta, where a U-II induced primary contractile response was reduced upon a secondary re-challenge after 5-hours. Studies were undertaken to characterise cell lines expressing native (SJCRH30) and recombinant human hUT (HEK293 and CHO)
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Ong, Kwok-leung. "Metabolic syndrome its prevalence and association with urotensin II /." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B3723058X.

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Ong, Kwok-leung, and 王國良. "Metabolic syndrome: its prevalence and association with urotensin II." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B3723058X.

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Eyre, Heather. "Urotensin II in the development of experimental chronic kidney disease." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/urotensin-ii-in-the-development-of-experimental-chronic-kidney-disease(e12bed8b-1bef-4bd1-9b19-5546ce7e1af9).html.

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Urotensin II (UII) is a potent peptide hormone with a complex species and vessel-dependent vascular profile. UII and the homologous UII-related peptide (URP) bind to the g-protein coupled urotensin II receptor (UT) with high affinity. The peptide ligands and receptor have been detected in numerous human and rat tissues including heart, brain and kidney. The kidney is a major source of UII, which appears to act as both an endocrine and paracrine mediator of renal function. UII has been shown to influence renal blood flow, glomerular filtration rate and sodium handling in the renal tubules. More
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Affolter, Jonathan Theodore. "Vasoactive hormone studies in man using urotensin II and vasopressin." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/28010.

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Using the established method of bilateral venous occlusion plethysmography to measure forearm blood flow, combined with intra-arterial infusion of drugs into the brachial artery, we sought to determine the effects of urotensin II on human forearm blood flow. Other methods such as the Aellig venous displacement technique, to assess venous tone, and pulse wave analysis, to quantify arterial stiffness were also used during local and systemic urotensin II intravenous infusions respectively. Doppler flowmetry was used to assess skin microcirculation combined with intra-dermal peptide injection resp
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Bousette, Nicolas. "The role of urotensin-II in atherosclerosis and ischemic cardiomyopathy /." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111848.

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Atherosclerosis, a vascular disease which may lead to coronary artery occlusion and consequent myocardial infarction is primarily caused by dyslipidemia. Ischemic cardiomyopathy due to atherosclerosis is the leading cause of morbidity and mortality in the western world today. Vasoactive factors are increasingly being recognized not only as contributors to atherosclerotic plaque formation, but also to cardiac function and remodeling following ischemic cardiac injury. Urotensin II (UII) is one such vasoactive factor. UII possesses a wide range of cardiovascular effects, from contraction of the r
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Ahmed, Shenge [Verfasser]. "Suche, Reinigung und Identifizierung eines Urotensin II metabolisierenden Enzyms / Shenge Ahmed." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2010. http://d-nb.info/1024335186/34.

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menegolo, mirko. "Human primary aldosteronism: from clinical observations to in-vivo and ex-vivo studies on the pressor effects of Urotensin II." Doctoral thesis, Università degli studi di Padova, 2013. http://hdl.handle.net/11577/3426182.

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In a patient affected by primary aldosteronism we have identified the presence of a pheochromocytoma not secreting catecholamines. The analysis of the transcriptome in the pheochromocytoma revealed a high expression of Urotensin II (UII). UII is a somatostatin-like cyclic 11-aminoacid vasoconstrictor peptide, first identified in the teleost fish caudal-neuro-secretory system and then in humans, that has been demonstrated to be a potent vasoactive peptide involved in the physiology and pathophysiology of the cardiovascular system through mechanisms still largely unknown. Its action is now the
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Egginger, Johann-Günther. "Les urotensines dans le système nerveux central : de l'urotensine-II spinale à un nouveau neuropeptide endocrine, l'URP (urotensin-II-related peptide) : approche cytofonctionnelle chez la souris et le rat." Paris 6, 2006. http://www.theses.fr/2006PA066257.

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En 2003, un peptide apparenté à l’urotensine-II (UII), l’urotensin-II-related peptide (URP), a été isolé à partir d’extraits de cerveau de rat. Dans l’hypothèse de l’existence de marqueurs communs aux motoneurones et aux neurones endocrines, nous avons étudié l’expression centrale des gènes de l’UII et de l’URP chez la souris et le rat. Par une approche cytofonctionnelle, nous avons montré que ces deux peptides ainsi que leurs ARNm sont exprimés au sein de motoneurones appartenant à la moelle épinière et particulièrement au niveau lombo-sacré ; l’URP est aussi localisé dans des fibres de l’émi
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Sorato, Elisa. "Attività pro-angiogenica di urotensina-II su cellule endoteliali vascolari umane." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3427531.

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Urotensin-II (U-II) is a cyclic peptide, originally isolated from the urophysis of the goby Gillichthys mirabilis. The human form of U-II (hU-II) is a cyclic undecapeptide. Mature hU-II is synthesized from a large precursor molecule, the prepro-U-II, whose mRNA has been found in many tissues. U-II has been identified as the endogenous ligand of a specific high-affinity receptor, recently identified as the orphan receptor GPR14 which has been renamed urotensin receptor (UT). The human UT isoform belongs to the class A superfamily of G-protein-coupled receptors. The principal physiological role
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Book chapters on the topic "Urotensin II"

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Albanese, Isabella, and Adel Schwertani. "Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease." In Biomarkers in Cardiovascular Disease. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-7678-4_6.

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Albanese, Isabella, and Adel Schwertani. "Circulating Vasoactive Peptide Urotensin II and Relationships with Cardiovascular Disease." In Biomarkers in Cardiovascular Disease. Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7741-5_6-1.

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Mallamaci, Francesca, Daniela Leonardis, and Maria Borrajo. "Role of Novel Biomarkers in Chronic Kidney Disease: Urotensin II." In Cardiorenal Syndrome. Springer Milan, 2010. http://dx.doi.org/10.1007/978-88-470-1463-3_23.

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Brkovic, A., P. Lampron, M. Létourneau, and A. Fournier. "Identification of Key-Residues of Urotensin II, a Potent Mammalian Vasoconstrictor." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_338.

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Grieco, Paolo, Riccardo Patacchini, Alfonso Carotenuto, Carlo A. Maggi, Ettore Novellino, and Paolo Rovero. "Design, Synthesis and Conformational Analysis of Human Urotensin II (U-II) Analogues with Lactam Bridge." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_293.

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Konno, Norifumi. "Urotensin II." In Handbook of Hormones. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-12-801028-0.00011-8.

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Konno, Norifumi. "Urotensin II." In Handbook of Hormones. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-820649-2.00038-3.

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LIHRMANN, ISABELLE, HOWARD A. BERN, and HUBERT VAUDRY. "Urotensin II and Urotensin II–Related Peptide." In Handbook of Biologically Active Peptides. Elsevier, 2006. http://dx.doi.org/10.1016/b978-012369442-3/50112-4.

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Lihrmann, Isabelle, Hervé Tostivint, Howard Bern, and Hubert Vaudry. "Urotensin II Peptides." In Handbook of Biologically Active Peptides. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-385095-9.00127-5.

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Davenport, Anthony. "Urotensin-II Receptor." In xPharm: The Comprehensive Pharmacology Reference. Elsevier, 2007. http://dx.doi.org/10.1016/b978-008055232-3.60208-9.

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Conference papers on the topic "Urotensin II"

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Merlino, Francesco, Ali M. Yousif, Salvatore Di Maro, et al. "Synthesis of N-Methyl and Azasulfuryl Urotensin-II(4-11) Derivatives." In The 24th American Peptide Symposium. Prompt Scientific Publishing, 2015. http://dx.doi.org/10.17952/24aps.2015.184.

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Wang, Dan, Xiangjun Li, and Cai Li. "The effects of urotensin II and its receptor in rat renal interstitial fibrosis." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6029049.

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Grieco, Paolo, Michele Caraglia, Silvia Zappavigna, et al. "Urotensin-II Receptor Regulates Cell Mobility/Invasion and Determines Prognosis of Bladder Cancer." In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.078.

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