Academic literature on the topic 'Usnic acid concentration'

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Journal articles on the topic "Usnic acid concentration"

1

Yano-Melo, Adriana Mayumi, Carlos Vicente, and Lauro Xavier-Filho. "Influence of Cladonia substellata Vainio extracts and usnic acid on germination and growth of Allium cepa L. seedlings." Bryophyte Diversity and Evolution 16, no. 1 (1999): 11–15. http://dx.doi.org/10.11646/bde.16.1.5.

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The effect of lichen extracts obtained from Cladonia substellata and its main constituent, usnic acid, on the germination and growth of onion (Allium cepa L.) seedlings was investigated. No significant inhibitory effect of the lichen extracts and usnic acid on germination was found, except of usnic acid at the concentration of 726.7 mM. Growth inhibition of the radicle and of the hypocotyl of the seedlings was found for the total extract and for usnic acid in concentrations of 290.6 mM and 726.7 mM.
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2

Bačkor, M., J. Hudá, M. Repčák, W. Ziegler§, and M. Bačkorová. "The Influence of pH and Lichen Metabolites (Vulpinic Acid and (+) Usnic Acid) on the Growth of the Lichen Photobiont Trebouxia 1rregularis." Lichenologist 30, no. 06 (1998): 577–82. http://dx.doi.org/10.1017/s0024282992000574.

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AbstractThe quantitative response to two lichen metabolites, vulpinic acid and (+) usnic acid, on biomass production by the photobiontTrebouxia irregularis, isolated from the lichenCladina mitis, was determined experimentally. The presence of usnic acid resulted in inhibition of photobiont growth, and the effect depended on the pH of the culture medium. The concentration effect of usnic acid was observed. The application of vulpinic acid almost completely inhibited the growth ofT.irregularisand no significant differences were found among samples at different medium pH values.
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3

Bačkor, M., J. Hudá, M. Repčák, W. Ziegler§, and M. Bačkorová. "The Influence of pH and Lichen Metabolites (Vulpinic Acid and (+) Usnic Acid) on the Growth of the Lichen Photobiont Trebouxia Irregularis." Lichenologist 30, no. 6 (1992): 577–82. http://dx.doi.org/10.1006/lich.1998.0166.

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AbstractThe quantitative response to two lichen metabolites, vulpinic acid and (+) usnic acid, on biomass production by the photobiont Trebouxia irregularis, isolated from the lichen Cladina mitis, was determined experimentally. The presence of usnic acid resulted in inhibition of photobiont growth, and the effect depended on the pH of the culture medium. The concentration effect of usnic acid was observed. The application of vulpinic acid almost completely inhibited the growth of T.irregularis and no significant differences were found among samples at different medium pH values.
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4

Khramchankova, V., and R. Novikau. "Extraction efficiency analysis of usnic acid from lichens of Belarusian Polesie." Bulletin of Science and Practice 4, no. 6 (2018): 23–32. https://doi.org/10.5281/zenodo.1289323.

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The extraction efficiency of usnic acid by acetone, ethanol and benzene from lichens Evernia prunastri, Ramalina pollinaria and Cladonia arbuscula was investigated. The methods of cold maceration of biomass with the appropriate solvent and extraction in the Soxhlet apparatus — directly and with preliminary cold maceration of the biomass with hexane were used. The extraction efficiency of usnic acid from the biomass Evernia prunastri and Ramalina pollinaria was greatest when using the method of cold maceration with hexane for 7 days, followed by extraction with ethanol in the Soxhlet appa
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5

Fitriani, Lili, Afifah, Friardi Ismed, and Amri Bakhtiar. "Hydrogel Formulation of Usnic Acid and Antibacterial Activity Test Against Propionibacterium acne." Scientia Pharmaceutica 87, no. 1 (2018): 1. http://dx.doi.org/10.3390/scipharm87010001.

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Usnic acid is known for its remarkable antimicrobial activity. The aim of this research was to formulate hydrogel of usnic acid and evaluate the antibacterial activity against Propionibacterium acne. Due to low solubility of usnic acid, solid dispersion was prepared using PVP K-30. In this study, intact usnic acid (UA) and usnic acid-solid dispersion (UA-SD) was formulated in hydrogel using several gelling agents: Aqupec HV-505, sodium alginate and HPMC K 100M. Concentration of each gelling agent was optimized for hydrogel base. All of hydrogel base showed homogenous gel, pH at range 5.37–6.33
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6

SMEDS, Annika I., and Minna-Maarit KYTÖVIITA. "Determination of usnic and perlatolic acids and identification of olivetoric acids in Northern reindeer lichen (Cladonia stellaris) extracts." Lichenologist 42, no. 6 (2010): 739–49. http://dx.doi.org/10.1017/s002428291000037x.

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AbstractThe ecologically important lichen Cladonia stellaris forms thick carpets in boreal forest floors. In addition to affecting temperature and water conditions in the soil underneath, the secondary metabolites formed by the lichen layer are of ecological interest. In this paper, we investigated the distribution of lichen acids in C. stellaris collected at different latitudes in Finland and developed methods to quantify the two optical enantiomers of usnic acid separately. The lichen extracts were analysed by high-performance liquid chromatography (HPLC) with UV and mass spectrometric (MS)
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7

Araújo, Hallysson Douglas Andrade de, Hianna Arely Milca Fagundes Silva, José Guedes da Silva Júnior, Mônica Camelo Pessoa de Azevedo Albuquerque, Luana Cassandra Breitenbach Barroso Coelho, and André de Lima Aires. "The Natural Compound Hydrophobic Usnic Acid and Hydrophilic Potassium Usnate Derivative: Applications and Comparisons." Molecules 26, no. 19 (2021): 5995. http://dx.doi.org/10.3390/molecules26195995.

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Usnic acid is the best-studied lichen metabolite, presenting several biological activities, such as antibacterial, immunostimulating, antiviral, antifungal, anti-inflammatory, and antiparasitic agents; despite these relevant properties, it is a hydrophobic and toxic molecule. In this context, scientific research has driven the development of innovative alternatives, considering usnic acid as a source of raw material in obtaining new molecules, allowing structural modifications (syntheses) from it. The purpose is to optimize biological activities and toxicity, with less concentration and/or res
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8

Pires, Regina Helena, Rodrigo Lucarini, and Maria Jose Soares Mendes-Giannini. "Effect of Usnic Acid on Candida orthopsilosis and C. parapsilosis." Antimicrobial Agents and Chemotherapy 56, no. 1 (2011): 595–97. http://dx.doi.org/10.1128/aac.05348-11.

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ABSTRACTThe activity of usnic acid againstCandida orthopsilosisandCandida parapsilosison planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potentin vitroactivities against differentCandidaspecies were obtained. The metabolic activity of sessile cells ofC. parapsilosiscomplex was reduced by 80% at four times the 80% inhibitory concentration. Thein vitrostudies support further efforts to determine whether usnic acid can be used clinically to cure patients withCandidainfections.
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9

Kikowska, Małgorzata, Barbara Thiem, Karolina Jafernik, et al. "Effect of Elicitation with (+)-Usnic Acid on Accumulation of Phenolic Acids and Flavonoids in Agitated Microshoots of Eryngium alpinum L." Molecules 26, no. 18 (2021): 5532. http://dx.doi.org/10.3390/molecules26185532.

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The present work was aimed at studying the potential of elicitation on the accumulation of phenolic compounds in in vitro shoot cultures of Eryngium alpinum L., a protected plant from the Apiaceae family. The study examined the influence of (+)-usnic acid on the biomass growth as well as on the biosynthesis of the desired flavonoids and phenolic acids in the cultured microshoots. The phenolic compound content was determined by HPLC-DAD. The flavonoid of the highest concentration was isoquercetin, and the phenolic acids of the highest amount were rosmarinic acid, caffeic acid and 3,4-dihydroxyp
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10

Petrová, Klaudia, Miriam Bačkorová, Zuzana Demčišáková, et al. "Usnic Acid Isolated from Usnea antarctica (Du Rietz) Reduced In Vitro Angiogenesis in VEGF- and bFGF-Stimulated HUVECs and Ex Ovo in Quail Chorioallantoic Membrane (CAM) Assay." Life 12, no. 9 (2022): 1444. http://dx.doi.org/10.3390/life12091444.

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Natural products include a diverse set of compounds of drug discovery that are currently being actively used to target tumor angiogenesis. In the present study, we evaluated the anti-angiogenic activities of secondary metabolite usnic acid isolated from Usena antarctica. We investigated the in vitro effects on proliferation, migration, and tube formation of VEGF- and bFGF-stimulated HUVECs. Ex ovo anti-angiogenic activity was evaluated using the CAM assay. Our findings demonstrated that usnic acid in the concentration of 33.57 µM inhibited VEGF (25 ng/mL) and bFGF (30 ng/mL)-induced HUVECs pro
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