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Journal articles on the topic 'Uterine fibroids'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

x, Chetna. "Uterine Fibroids." International Journal of Science and Research (IJSR) 11, no. 9 (2022): 575–76. http://dx.doi.org/10.21275/sr22911131215.

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Nadir qızı Kərimova, Sevinc. "Uterine fibroids." NATURE AND SCIENCE 07, no. 02 (2021): 22–24. http://dx.doi.org/10.36719/2707-1146/07/22-24.

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Fibroids (especially large ones) deform the uterine cavity, compressing the fallopian tubes, making it difficult for sperm to move. In addition, in women with fibroids, in many cases, the hormonal background is disturbed, as a result of which a woman may not ovulate. The factors we have listed can lead to infertility in women. Doctors recommend women with fibroids to treat fibroids during the planning stage of pregnancy or, in some cases, to remove fibroids before pregnancy. A woman can plan a pregnancy 6 months after the fibroid is removed. Key words: fibroma, uterus, pregnancy

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Ali Sheikh, Md Sayed, and Umme Salma. "Determine the Relationship Between Hypertension and Uterine Fibroids." Yemen Journal of Medicine 04, no. 01 (2025): 160–63. https://doi.org/10.63475/yjm.v4i1.0005.

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Background: Numerous studies have linked uterine fibroids to hypertension, suggesting that this condition may be a risk factor unique to women. These days, fibroids are the main cause of myomectomy and hysterectomy. This study aimed to ascertain the relationship between uterine fibroids and hypertension in Saudi women. Methods: This case-control study was carried out between January 2023 and January 2024 on patients with uterine fibroids and non-uterine fibroids who had an appointment for surgery at the gynecological department of the Maternal and Children Hospital (MCH) Sakaka, Aljouf, Saudi

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Sheikh, Md Sayed Ali, and Umme Salma. "Determine the Relationship Between Hypertension and Uterine Fibroids." Yemen Journal of Medicine 4, no. 1 (2025): 160–63. https://doi.org/10.63475/yjm.v4i1.0005.

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Background: Numerous studies have linked uterine fibroids to hypertension, suggesting that this condition may be a risk factor unique to women. These days, fibroids are the main cause of myomectomy and hysterectomy. This study aimed to ascertain the relationship between uterine fibroids and hypertension in Saudi women. Methods: This case-control study was carried out between January 2023 and January 2024 on patients with uterine fibroids and non-uterine fibroids who had an appointment for surgery at the gynecological department of the Maternal and Children Hospital (MCH) Sakaka, Aljouf, Saudi

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Carrino, David A., Sam Mesiano, Nichole M. Barker, William W. Hurd, and Arnold I. Caplan. "Proteoglycans of uterine fibroids and keloid scars: similarity in their proteoglycan composition." Biochemical Journal 443, no. 2 (2012): 361–68. http://dx.doi.org/10.1042/bj20111996.

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Fibrosis is the formation of excess and abnormal fibrous connective tissue as a result of either a reparative or reactive process. A defining feature of connective tissue is its extracellular matrix, which provides structural support and also influences cellular activity. Two common human conditions that result from fibrosis are uterine fibroids (leiomyomas) and keloid scars. Because these conditions share a number of similarities and because their growth is due primarily to excessive extracellular matrix deposition, we compared the proteoglycans of uterine fibroids and keloid scars with corre

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Gurjeva, V. A., O. V. Kolyado, O. V. Remneva, and Yu A. Shadeeva. "Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy." Fundamental and Clinical Medicine 10, no. 1 (2025): 47–55. https://doi.org/10.23946/2500-0764-2025-10-1-47-55.

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Aim. To determine the optimal surgical treatment for uterine fibroids in patients with unfulfilled reproductive through the analysis of pregnancy course and outcomes following uterine artery embolization (UAE) and myomectomy.Materials and Methods. The study assessed pregnancy course and outcomes, as well as neonatal conditions, in 147 patients including those who: 1) underwent UAE; 2) underwent myomectomy; 3) had untreated uterine fibroids; 4) did not have uterine fibroids. Data collection was conducted retrospectively by reviewing medical records, including case histories, pregnancy and

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Abdelmtalab, Mohammed A. A., O. Tahir, K. Hussein, and Kamal Badawi. "Anatomical locations of uterine fibroids in Sudanese women." Anatomy Journal of Africa 9, no. 1 (2020): 1701–6. http://dx.doi.org/10.4314/aja.v9i1.6.

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Uterine fibroids are the commonest uterine neoplasms, they are benign tumors of smooth muscle origin. The study was done to look for the anatomical locations of uterine fibroids and their incidence in Sudanese women at Omdurman Maternity Hospital between 1st July 2014 to 5th October 2015. Their sociodemographic and ultrasound data were collected using a prepared questionnaire. The study included 138 confirmed cases of uterine fibroids out of 2968 investigated cases representing incidence rate of 4.6%. The highest incidence was found in the age group 36-40 years. Most dominant anatomical locati

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Khan, Maimoona Qadir, Zubeida Akhtar, and Jamila M. Naib. "Uterine Fibroids in Pregnancy." Journal of Gandhara Medical and Dental Science 9, no. 3 (2022): 30–33. http://dx.doi.org/10.37762/jgmds.9-3.314.

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OBJECTIVES: To determine the maternal and fetal outcomes associated with uterine fibroids in pregnancy. METHODOLOGY: This study was conducted in the Gynaecology Department of Mardan Medical Complex from January 2018 to December 2019. All pregnant women of any age or parity or gestational age with sonographic evidence of uterine fibroids were included. Demographic details, gestational age, symptoms related to fibrosis, size, number and location of the fibroid, mode of delivery, antenatal, intrapartum and postnatal complication, and neonatal outcome were entered in a predesigned proforma. RESULT

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Alhainiah, Maha, Elaf Aljifry, Ayman Alghamdi, et al. "Safety of pregnancy in uterine fibroids." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 8 (2018): 2985. http://dx.doi.org/10.18203/2320-1770.ijrcog20182924.

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Uterine fibroid is one of the most common intrauterine masses among females at the reproductive age. Pregnancy and uterine fibroids are highly correlated. Pregnancy-related hormones influence the size of uterine fibroids, and fibroids have many impacts on pregnancy. Although most if the uterine fibroids are asymptomatic during pregnancy, serious complications may occur. The main complications include abortion, premature rupture of membranes, premature labor, abruptio placentae, peripartum hemorrhage, fetal malpresentation, fetal intrauterine growth retardation, small for gestational age infant

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Mohson, Khaleel Ibraheem, and Mohammed Ali Jafaar Nori. "Efficiency of Uterine Fibroid Embolization in Symptomatic Iraqi Patients." Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ) 8, no. 2 (2025): 238–41. https://doi.org/10.54133/ajms.v8i2.2016.

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Background: Uterine fibroids are benign tumors of the smooth muscle of the uterus. Uterine artery embolization (UAE), a minimally invasive procedure performed by an interventional radiologist, causes fibroids to shrink and improves symptoms. Objective: To study the effectiveness of UFE in helping symptomatic Iraqi women achieve symptomatic relief. Methods: Fifty patients with symptomatic fibroid(s) who visited Kahramana Medical Center of Interventional Radiology between June 2022 and June 2023 were included in a prospective study. The patients were prepared for UFE under local anesthesia. This

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Made Indira Dianti Sanjiwani and I Made Widianantara. "Peranan Resveratrol terhadap Progresivitas Uterine Fibroid." KELUWIH: Jurnal Kesehatan dan Kedokteran 2, no. 2 (2021): 102–9. http://dx.doi.org/10.24123/kesdok.v2i2.4189.

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Uterine fibroids or leiomyomas are benign neoplasms that occur in the uterus and still become a health problem among women of reproductive age. Predominantly, uterine fibroids are found at productive age but some cases are found after menopause. Based on previous studies, there were 145 cases of uterine fibroids in 2014 and 69.7% were found in women over 40 years. Patients with uterine fibroids show a decreased quality of life with symptoms such as heavy uterine bleeding, pelvic pain, and loss of pregnancy. The pathogenesis of uterine fibroids is still unknown, but genetic factors, cytokines,

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Islam, Dr Md Menhazul, Dr Farzana Alam, Dr Syeeda Showkat, et al. "Impact of Vitamin D Supplementation among the Women with Uterine Fibroid in Different Age Groups." Scholars Journal of Applied Medical Sciences 10, no. 11 (2022): 2052–56. http://dx.doi.org/10.36347/sjams.2022.v10i11.042.

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Background: Uterine fibroid (UF) is a common tumor of the female reproductive system. Though most of the women with fibroids are asymptomatic, approximately 30% of them can mention about some severe symptoms like abnormal uterine bleeding, pelvic pain, anemia, back pain, urinary frequency and even infertility etc. Generally, among the patients with uterine fibroids, prevalence of vitamin D deficiency is found. But, the impact of vitamin D on reduction of the sizes the uterine fibroids are still unknown. Aim of the study: The aim of this study was to assess the impact of vitamin D supplementati

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Yadav, Rajni, Isotou Drammeh, and Mahendra Kumar Sahu. "Exploring uterine fibroids and its treatment in current scenario." IP International Journal of Comprehensive and Advanced Pharmacology 8, no. 3 (2023): 143–48. http://dx.doi.org/10.18231/j.ijcaap.2023.025.

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Uterine Fibroids (leiomyoma) are made of muscle cells and other grow tissues grow in and around of the wall of the uterus. Uterine fibroids benign tumors in women reproduction age worldwide. Many are discovered incidentally on clinically examination. Approximately 30% of women with uterine fibroids will present with severe symptoms, which can include abdominal uterine bleeding, anemia, pelvic pain and constipation. Infertility and recurrent miscarriage may also be symptoms of fibroids, depending on their location and size, especially for sub mucous and intramural myelomas distorting the uterin

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Abdullah, Ayesh Altalhi* Torky Ahmed Arab* Al bandari Khalid Althubaiti* Arwa Muneer Aljuhani*. "OVERVIEW OF MANAGEMENT APPROACHES OF UTERINE FIBROID." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 11 (2018): 12043–52. https://doi.org/10.5281/zenodo.1486097.

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<em>In this review we discuss possible management approaches of uterine fibroid. </em><em>Electronic search of journal articles relevant to the management approaches of uterine fibroids was performed through PubMed, and Embase up to 2018, with the following MeSH key words (uterine fibroid, interventions) within PubMed.</em><em> Uterine fibroids (leiomyomas or myomas) are the most popular pelvic tumors and one of the most widespread benignant tumors in women. A large number of women with uterine fibroids either remain asymptomatic or develop syndromes progressively over time. When patients are

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Golubka, Paweł, Agnieszka Wańkowicz, Marian Przylepa, et al. "Pregnant women suffering from uterine fibroids." Polish Journal of Public Health 125, no. 3 (2015): 166–68. http://dx.doi.org/10.1515/pjph-2015-0047.

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Abstract Introduction. Uterine fibroids are the most frequent benign tumors affecting sexual organs in women. It is estimated that they affect 20% of the female population, with the frequency in pregnant women ranging between 0.1-5%. In spite of the progress in the field of medicine, the actual cause of uterine fibroids has yet to be discovered. Aim. Analysis of the recent methods of dealing with uterine fibroids during pregnancy. Material and methods. A review of literature about dealing with pregnant, lying-in and parturient women suffering from uterine fibroids. Results. The research studie

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Poly, Rosemol, Anju Alex, and Usha Christopher. "Wandering Uterine Leiomyoma: A Case Report." International Journal of Research and Review 10, no. 3 (2023): 10–12. http://dx.doi.org/10.52403/ijrr.20230303.

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Wandering fibroids, commonly referred to as parasitic fibroids, are a relatively uncommon kind of extrauterine benign tumour in women of reproductive age. It has no myometrial connections and frequently develops in conjunction with other abdominopelvic structures' blood supply. Due to their odd placements and symptoms, these fibroids are challenging to diagnose by imaging. There are several hypotheses on the origin of parasitic fibroids, including the iatrogenic seeding of fibroid pieces after morcellation in laparoscopic myomectomy, and pedunculated subserosal fibroid separating from its stal

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Saba, Ghaffari, and Rahman Khatibur. "Obstetrics Outcomes of Uterine Fibroids: An Observational Study." International Journal of Current Pharmaceutical Review and Research 16, no. 4 (2024): 305–10. https://doi.org/10.5281/zenodo.12788792.

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Aim: The aim of the present study was to assess the obstetrics outcomes of uterine fibroids and their consequencesin a tertiary hospital.Methods: The present study was an observational study was undertaken in the Department of Obstetrics andGynaecology, Gauri Devi Institute of Medical Science & Hospital, Durgapur, West Bengal, India. The study wasconducted over a period of 12 months. 200 pregnant women who had USG findings of fibroid were enrolled inthis study.Results: The mean age of patients in study was 31 years with standard deviation of 5.85, but majority of patients(42%) were in the

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Tskhay, V. B., S. Zh Badmaeva, A. N. Narkevich, I. I. Tskhay, and A. V. Mikhaylova. "A predictive model for calculating the likelihood of recurrent uterine fibroids after surgical intervention." Fundamental and Clinical Medicine 6, no. 3 (2021): 64–70. http://dx.doi.org/10.23946/2500-0764-2021-6-3-64-70.

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Aim. To develop a predictive model for calculating the likelihood of recurrent uterine fibroids after myomectomy.Materials and Methods. We consecutively recruited 149 women aged 19 to 45 years who underwent myomectomy. Prediction of uterine fibroids was carried out using multivariate analysis including a classification tree (IBM SPSS Statistics). To construct a classification tree for predicting recurrent uterine fibroids, the following patient-related parameters were used as the input features: age, family history, nulliparity, past medical history of myomectomy, obesity, rapid fibroid growth

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Kanwar, Pushp, Mahesh Dixit, and Narendra Kumar Meena. "A Literary Review of Garbhashayarbuda in Ayurveda w.s.r. to Uterine Fibroid." International Research Journal of Ayurveda & Yoga 05, no. 02 (2022): 105–7. http://dx.doi.org/10.47223/irjay.2022.5218.

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Uterine fibroids are most common disease of women in reproductive age. Though uterine fibroids are benign in Nature; they reveal a wide range of symptoms like metrorrhagia, dysmenorrhea, menorrhagia, low back pain etc. Morden treatment protocols include hormonal therapy, myomectomy hysterectomy, and uterine artery embolization. Unwillingness for sustained hormone therapy and panic for surgery brings patients towards to Ayurveda. Ayurveda classics mention various pathological conditions that have features similar to fibroids. Ayurveda it is mandatory to know the correlation of uterine fibroids

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Dobrokhotova, Yu E., and I. Yu Ilina. "Uterine fibroids in premenopausal women." Medical Council, no. 13 (October 10, 2019): 123–28. http://dx.doi.org/10.21518/2079-701x-2019-13-123-128.

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Uterine fibroids are one of the commonest benign pelvic tumours with an estimated incidence of 20–40% in women during their reproductive years. Incidence rates for uterine fibroid diagnoses were highest in premenopausal age. The gynecologists are frequently faced with need for the administration of menopausal hormone therapy (MHT) in this group of patients with the onset of symptoms associated with estrogen deficiency; however, uterine fibroids represent a relative contraindication for the administration of MHT. In the present paper, we point out the need for conservative therapy of uterine fi

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Thomas, Lizann Elizabeth, Elizabeth Abraham, and Renjitha Bhaskaran. "Does vitamin D play a role in uterine fibroids? A case control study." Panacea Journal of Medical Sciences 13, no. 2 (2023): 323–27. http://dx.doi.org/10.18231/j.pjms.2023.062.

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Uterine fibroids are monoclonal tumors of uterine smooth muscle cells. They are found in 20-40% of females in the reproductive age group. Ovarian hormones play an important role in its etiology. Recent studies have shown that low serum 25(OH)vitamin D levels are associated with increased risk of uterine fibroids. To investigate the association between serum vitamin D levels and uterine fibroids.A case control study was conducted in a tertiary care hospital among 183 women between the age of 18-50 years with uterine fibroids who attended obstetrics and gynecology department and 183 women of the

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Ugwu, Favour Ebube, and Hyma P. "UTERINE FIBROIDS-A COMPREHENSIVE REVIEW." Journal of Advanced Scientific Research 14, no. 02 (2023): 01–08. http://dx.doi.org/10.55218/jasr.202314201.

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Uterine fibroid is a non-cancerous growth in the female uterus of a reproductive woman, ranging from age 40s andabove. Even though according to research, females of age 20s and 30s also have few chances of this growth in theiruterus, as long as they have reach a child bearing age (reproductive age); in this stage it is encouraged that such individualis treated with immediate effect to avoid the continuous multiplication of this growth. “Uterine fibroid embolism” can bea good choice for treatment, which is a minimally invasive technique. In other cases, where the fibroid case hasmultiplied so m

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Anuradha, R., and G. Rathi. "Presence and Impact of Uterine Fibroids in Women with Menstrual and Premenstrual Syndrome – A Statistical Analysis." International Journal of Membrane Science and Technology 10, no. 2 (2023): 3107–13. http://dx.doi.org/10.15379/ijmst.v10i2.3055.

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A number of non-invasive alternatives to hysterectomy are available for treating uterine fibroids, but they may not effectively relieve all symptoms. As a result, it has become increasingly important to use patient-reported outcomes to assess the success of these alternative therapies in reducing uterine fibroid symptoms. These symptoms can range from heavy menstrual bleeding to dysmenorrhea for women who experience menstrual and premenstrual syndrome. To standardize the assessment of fibroid-related symptoms, the Uterine Fibroid Indicators and Analysis of Patient Recovery survey form (UFS-APR

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Micić, Jelena, Maja Macura, Mladen Andjić, et al. "Currently Available Treatment Modalities for Uterine Fibroids." Medicina 60, no. 6 (2024): 868. http://dx.doi.org/10.3390/medicina60060868.

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Uterine fibroids (leiomyomas and myomas) are the most common benign gynecological condition in patients presenting with abnormal uterine bleeding, pelvic masses causing pressure or pain, infertility and obstetric complications. Almost a third of women with fibroids need treatment due to symptoms. Objectives: In this review we present all currently available treatment modalities for uterine fibroids. Methods: An extensive search for the available data regarding surgical, medical and other treatment options for uterine fibroids was conducted. Review: Nowadays, treatment for fibroids is intended

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Fatima, Amani, Shahryar Ahmad, Abdullah Meraj, et al. "ASSOCIATION OF UTERINE FIBROIDS AND HYPOTHYROIDISM AMONG WOMEN OF REPRODUCTIVE AGE." Insights-Journal of Health and Rehabilitation 3, no. 3 (Health & Allied) (2025): 148–54. https://doi.org/10.71000/9y86pe22.

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Background: Uterine fibroids are among the most common benign tumors in women of reproductive age, often associated with hormonal imbalances. Hypothyroidism, another hormone-related disorder, has been reported to influence gynecological health, including menstrual irregularities and infertility. Since both conditions are hormonally driven, the possibility of an interrelation between thyroid dysfunction—particularly elevated thyroid-stimulating hormone (TSH) levels—and fibroid development warrants investigation to inform clinical assessment and management strategies. Objective: To assess the re

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Rawat, Rajneesh, Manik Gedam, Jyoti Baghel, and Shalini Baghel. "A rare association of uterine leiomyoma with mesenteric vein thrombosis and bowel gangrene: case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 4 (2021): 1721. http://dx.doi.org/10.18203/2320-1770.ijrcog20211167.

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Uterine fibroids are the most common benign pelvic tumors in women. There are many complications reported with fibroids. However, mesenteric vein thrombosis and small bowel gangrene caused by a uterine fibroid are rare. This manuscript reports a rare case of 40 year female with a large uterine fibroid associated with mesenteric vein thrombosis and bowel ischemia. She underwent exploratory laparotomy in which resection of gangrenous bowel including jejunum and ileum was done along with left sided jejunostomy and right sided ileostomy. Total abdominal hysterectomy with bilateral salpingooophorec

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Aganezova, Natalia V., Sergey S. Aganezov, and Maria M. Buryak. "Characteristics of fibroid nodes in dynamics when using multiphasic and monophasic combined hormonal contraceptives." Journal of obstetrics and women's diseases 74, no. 1 (2025): 14–25. https://doi.org/10.17816/jowd636389.

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BACKGROUND: The increasing prevalence of uterine fibroids at the age of 20–35 years and late fertility intentions are modern trends in women’s lives. Combined hormonal contraceptives level out cyclic fluctuations of sex steroids in the natural menstrual cycle; can be used by patients with fibroid nodes for contraception; and have a protective effect on uterine fibroids. The literature does not provide comparative data on the use of multi- and monophasic combined hormonal contraceptives with ethinyl estradiol by patients with uterine fibroids. AIM: The aim of this study was to assess the charac

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Ahn, Dao Le Thi, Vu Duong Van, Thang Vuong Toan, and Anh Nguyen Duy. "#357 : Uterine Fibroids Treatment Using Radio Frequency Ablation at Hanoi Obstetrics and Gynecology Hospital, Vietnam: A Preliminary Assessment." Fertility & Reproduction 05, no. 04 (2023): 538. http://dx.doi.org/10.1142/s2661318223742935.

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Complicated uterine fibroids in young women, who wish to preserve fertility, and/ or unwilling to undergo surgery, or those having uterine fibroids deemed difficult for surgical intervention, need a less invasive and effective treatment method. Objectives: To evaluate the results of treatment of uterine fibroids by Radio Frequency Ablation (RFA) at Hanoi Obstetrics and Gynecology Hospital, Vietnam (HOGH) for 8 months. Materials and Methods: A cross-sectional study with longitudinal follow-up. Patients with symptomatic uterine fibroids including abnormal uterine bleeding, pelvic pain, anemia; i

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TATARCHUK, T. F., N. V. KOSEY, S. I. REGEDA, O. V. ZANKO, and K. D. PLAKSIIEVA. "TO THE QUESTION ON UTERINE FIBROIDS DURING PREGNANCY." Scientific digest of association of obstetricians and gynecologists of Ukraine, no. 1(47) (September 8, 2021): 54–59. http://dx.doi.org/10.35278/2664-0767.1(47).2021.242698.

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Uterine fibroids is an extremely common tumor of the female reproductive system, among whose manifestations are infertility, spontaneous abortions, incorrect fetal position, placenta previa, premature delivery, bleeding during and after delivery, and an increased risk of cesarean section. According to the literature, myomas are changing in size during pregnancy and in the postpartum period. Aim of the study. To assess the dynamics of uterine fibroid size change during pregnancy and the effect of an existing uterine fibroid on the course of pregnancy and labor. Materials and methods. Outpatient

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Jones, Siân, Peter O'Donovan, and David Toub. "Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids." Obstetrics and Gynecology International 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/194839.

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The use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which entails the conversion of an external electromagnetic or ultrasound waves into intracellular mechanical energy, generating heat. What has emerged from two decades of peer-reviewed research is the concept that hyperthermic fibroid ablation, regardless of the thermal energy source, can create large area

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Shivani, Chauhan, and Megha Bahuguna Dr. "MANAGEMENT OF UTERINE FIBROID THROUGH AYURVEDA – A CASE STUDY." World Journal of Pharmaceutical Science and Research 4, no. 2 (2025): 892–98. https://doi.org/10.5281/zenodo.15302631.

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Uterine fibroid (leiomyomas, fibromyomas or simply myomas) are generally benign uterine neoplasms, commonly encountered in gynaecological practice (5-20% of women in the reproductive age group). They are slow growing tumours and take 3-5 years to be clinically palpable, unlike ovarian tumours. The fibroids are located in uterine and extra uterine are - A) Uterine = i) intramural / interstitial- grow within interstitial wall 75% ii) Sub mucous - grow towards peritoneal surface 5% iii) Sub serous - grow towards the uterine cavity 15% B) Extra uterine- most common in cervical fibroid.Le

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Ng, Vivian Wai-Yan, and Vincent Yuk-Tong Cheung. "Ultrasound-Guided High-Intensity Focused Ultrasound of Uterine Fibroids and Adenomyosis: An 11-Year Experience from a Single Center in Hong Kong." Journal of Clinical Medicine 13, no. 16 (2024): 4788. http://dx.doi.org/10.3390/jcm13164788.

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Introduction: This study evaluated the efficacy and safety of ultrasound-guided high-intensity focused ultrasound (HIFU) in treating symptomatic uterine fibroids and adenomyosis. Methods: HIFU treatments performed in premenopausal women with symptomatic uterine fibroids and adenomyosis were analyzed retrospectively. Lesion volume reduction, change in symptoms of menstrual pain, and quality of life were examined. Major and minor complications, together with re-intervention rates, were evaluated. Results: Eighty-one HIFU treatments were performed in seventy-nine premenopausal women. The follow-u

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Swati. "An Observational Study Assessing Clinical Profile and Factors Associated with Uterine Fibroids at Tertiary Care Hospital." International Journal of Current Pharmaceutical Review and Research 15, no. 10 (2023): 529–33. https://doi.org/10.5281/zenodo.11634958.

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AbstractAim: The aim of the present study to assess the clinical profile and factors associated with uterine fibroids attertiary health care center.Material & Methods: This was a prospective study carried out in department of obstetrics and Gynaecology forthe period of nine months . Study population were patients presenting with uterine fibroid. Total 200 patients werestudied during study period.Results: Majority of the patients were in the age group of 31 -40 years followed by 41-50 years. Fibroid was notseen below 20 years. Majority of the patients with fibroid were with parity 1-2. 22 p

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Obiozor AA and Obiozor CG. "Large submucous uterine fibroid mass." Ibom Medical Journal 7, no. 2 (2024): 362–64. http://dx.doi.org/10.61386/imj.v7i2.453.

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Background: Uterine fibroids or leiomyomas, are common benign tumors originating from the smooth muscle cells of the uterus. While typically asymptomatic, large submucous fibroids can cause significant clinical manifestations, including abnormal uterine bleeding, pelvic pain, and reproductive issues. Radiological imaging, such as ultrasound, played a crucial role in the accurate diagnosis and characterization of these fibroids, guiding appropriate clinical management decisions. Methods: We present a case report of a 28-year-old female with complaints of heavy menstrual bleeding and pelvic disc

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Emmanuel Kobina Mesi, Edzie, Dzefi-Tettey Klenam, Brakohiapa Edmund Kwakye, et al. "Evaluation of the anatomical locations and sizes of uterine fibroids from ultrasound examination in Ghana." African Health Sciences 23, no. 4 (2023): 438–50. http://dx.doi.org/10.4314/ahs.v23i4.48.

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Background: Uterine fibroids locations and sizes, have significant influences on the quality of life of women especially pregnantwomen and on live birth rate.Objectives: To determine the anatomical locations and sizes of uterine fibroids and assess any possible associations with age groups.Methods: This retrospective study reviewed the locations and sizes of a total of 3,542 patients who were ultrasonographically diagnosed with uterine fibroids from January 2019 to December 2021. The obtained data were analysed using GNU PSPP, and Python on Jupyter Notebook with statistical significance level

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Udobi, S.I, A.C Onuh, J.I Udobi, and C.O. Ezeama. "Correlation Of Structural Uterine Abnormalities With Abnormal Uterine Bleeding Among Premenopausal Women With Infertility." International Journal Of Health & Medical Research 02, no. 09 (2023): 315–22. https://doi.org/10.5281/zenodo.8383117.

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Objective: To document the various structural uterine abnormalities detected on transabdominal ultrasonography (TAUS) and hysterosalpingography (HSG) of premenopausal women with infertility and abnormal uterine bleeding (AUB) and determine whether the structural abnormalities correlate well with the clinical forms of AUB among the patients. Methodology: This is a prospective and analytical study of 98 infertile women with history of AUB, referred for HSG. Clinical history including the forms of AUB were obtained from the subjects. Subjects were evaluated with TAUS and HSG after obtaining both

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Jamaluddin, M. Fairuz B., Yi-An Ko, Manish Kumar, et al. "Proteomic Profiling of Human Uterine Fibroids Reveals Upregulation of the Extracellular Matrix Protein Periostin." Endocrinology 159, no. 2 (2017): 1106–18. http://dx.doi.org/10.1210/en.2017-03018.

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Abstract The central characteristic of uterine fibroids is excessive deposition of extracellular matrix (ECM), which contributes to fibroid growth and bulk-type symptoms. Despite this, very little is known about patterns of ECM protein expression in fibroids and whether these are influenced by the most common genetic anomalies, which relate to MED12. We performed extensive genetic and proteomic analyses of clinically annotated fibroids and adjacent normal myometrium to identify the composition and expression patterns of ECM proteins in MED12 mutation–positive and mutation–negative uterine fibr

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R. Podder, Manjiri, Rahul Podder, and Poonam V. Shivkumar. "Demographic parameters of women with uterine fibroids presenting as abnormal uterine bleeding." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 7 (2018): 2915. http://dx.doi.org/10.18203/2320-1770.ijrcog20182906.

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Background: Uterine fibroids are commonest benign uterine tumors. Only about 25% women with fibroids are symptomatic. Around 70-80% are discovered incidentally during routine pelvic examination. Using ultrasonography screening, some authors have estimated a cumulative incidence of 70% in all women by age 50. Symptoms attributable to fibroids are mainly abnormal uterine bleeding (AUB), pelvic pressure, pain, and reproductive dysfunction. Heavy and/or prolonged menses is the typical bleeding pattern with myomas. Uterine fibroids are a leading cause of hysterectomy in perimenopausal women, thus,

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Yoon, Sang-Wook, Chan Lee, Kyoung Ah Kim, and Sang Heum Kim. "Contrast-Enhanced Dynamic MR Imaging of Uterine Fibroids as a Potential Predictor of Patient Eligibility for MR Guided Focused Ultrasound (MRgFUS) Treatment for Symptomatic Uterine Fibroids." Obstetrics and Gynecology International 2010 (2010): 1–4. http://dx.doi.org/10.1155/2010/834275.

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Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a non-invasive treatment approach for symptomatic uterine fibroids. One imaging characteristic considered in selecting patients who may benefit from MRgFUS of their uterine fibroids is the signal intensity of the fibroid compared with surrounding myometrium on T2-weighted MR images. Previous reports suggest that hyper-intense fibroids are less amenable to MRgFUS compared with iso- or hypo-intense fibroids. In this case study, we utilized contrast-enhanced dynamic MR imaging to further characterize the vascularity of a hyper-inten

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Dubinskaya, E. D., S. N. Kolesnikova, E. V. Aleshkina, and A. S. Gasparov. "Chronic sterile inflammation in the pathogenesis of benign myometrial diseases." Voprosy ginekologii, akušerstva i perinatologii 23, no. 1 (2024): 84–93. http://dx.doi.org/10.20953/1726-1678-2024-1-84-93.

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This article presents an analysis of current literary sources on the role of chronic sterile inflammation in the development of proliferative diseases of the myometrium (adenomyosis, uterine fibroids). DAMPs (damage-associated molecular patterns) are considered as a significant marker of inflammation severity in these diseases. The pathogenesis of both uterine fibroids and adenomyosis is based on similar mechanisms related to chronic sterile inflammation in response to abnormal cell division. Neoangiogenesis, neoneurogenesis and fibrosis are likely to be the result of inflammation and contribu

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Goswami, Sunita, and Rashmi Sharma. "AN AYURVEDIC REVIEW OF UTERINE FIBROIDS." International Journal of Advanced Research 10, no. 01 (2022): 177–81. http://dx.doi.org/10.21474/ijar01/14028.

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Uterine fibroidsare the most common solid benign tumours in women of reproductive age. Histologically this tumour is composed of smooth muscle and fibrous connective tissue, called as uterine leiomyoma, myoma, fibromyoma. Uterine fibroid related symptoms negatively impact physical and social activities, womens health related quality of life and work productivity.The postmenopausal incidence, although postmenopausal leiomyomas are smaller and fewer. Though uterine fibroids are non-cancerous in character they exhibit a wide range of symptoms like dysmenorrhea, menorrhagia, metrorrhagia, lower ba

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Don, Emma E., Mei-An Middelkoop, Wouter J. K. Hehenkamp, Velja Mijatovic, Arjan W. Griffioen, and Judith A. F. Huirne. "Endometrial Angiogenesis of Abnormal Uterine Bleeding and Infertility in Patients with Uterine Fibroids—A Systematic Review." International Journal of Molecular Sciences 24, no. 8 (2023): 7011. http://dx.doi.org/10.3390/ijms24087011.

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Uterine fibroids are the most common benign tumors in women, with abnormal uterine bleeding (AUB) as the main reported symptom. Additionally, an association between fibroids and infertility has been established, especially if the fibroid protrudes in the uterine cavity. Hormonal therapy is associated with side-effects and as well as hysterectomy, which is incompatible with a desire to conceive. To improve treatment, it is essential to unravel the etiology of fibroid-related symptoms. We aim to evaluate endometrial angiogenesis in women with fibroids, with and without AUB, and the influence of

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Ivanova, Yoana G., Muhammad Gohar, Elitsa H. Gyokova, Angel D. Yordanov, and Dobromir D. Dimitrov. "Use of High-Intensity Focused Ultrasound (HIFU) in Treating Uterine Fibroids: A Case Report." Journal of Biomedical and Clinical Research 15, no. 2 (2022): 178–81. http://dx.doi.org/10.2478/jbcr-2022-0025.

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Summary Uterine fibroids are the most common benign uterine tumours in women of reproductive age. They can present with different symptoms, including menorrhagia, cramping lower abdominal pain, bloating, urinary/bowel symptoms, spotting, and infertility. Management could be medical and surgical. Other options include uterine artery embolization and non-invasive treatment with high-intensity focused ultrasound (HIFU). We present a case of a 32-year-old woman with menorrhagia and severe pelvic pain. Ultrasound examination revealed an intramural myoma measuring 93x98x87 mm. The patient signed inf

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Costa, Ana R., Ana P. Carvalho, Diana R. Martins, et al. "Series of 55 pregnancies following ulipristal acetate treatment of symptomatic uterine fibroids." Journal of Endometriosis and Pelvic Pain Disorders 12, no. 3-4 (2020): 170–75. http://dx.doi.org/10.1177/2284026520932468.

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Introduction: Treatment with ulipristal acetate effectively controls excessive bleeding due to uterine fibroids and reduces their size. Uterine fibroid size reduction is expected to improve the results of the myomectomy and the reproductive prospects of the patient. Methods: Retrospective and descriptive analysis of a series of 53 patients who achieved pregnancy after being treated for symptomatic uterine fibroids. The primary endpoints were pregnancy and birth outcomes in women with symptomatic uterine fibroids that conceived following at least one course of therapy with ulipristal acetate 5

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Asaolu, Oluseyi Ayoola, David Tolulope Ejiroghene Ejenobo, and Olubunmi Abraham Alabi. "Laparoscopic Myomectomy for Huge Uterine Fibroid in Sub-Saharan Africa: A Case Report." African Journal of Reproduction and Gynaecological Endoscopy 8, no. 1 (2023): 32–36. http://dx.doi.org/10.4103/ajrge.ajrge_9_23.

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Abstract The prevalence of extensive and multiple uterine fibroids among the Black African population is a significant concern, as it limits the available management options. The focus on girl child education and improvement in women empowerment have contributed to an increased demand for less invasive options in the management of uterine fibroids. This trend aims to improve cosmesis and, more importantly, facilitate an early return to work and normal activity. In sub-Saharan Africa, the available management options for uterine fibroids have primarily been limited to abdominal myomectomy and h

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Matsushima, Hisakazu, Ken Kageyama, Akira Yamamoto, et al. "Observation of Intramural Fibroid Expulsion on MRI after Uterine Artery Embolization." Case Reports in Radiology 2021 (August 14, 2021): 1–5. http://dx.doi.org/10.1155/2021/7970894.

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Uterine artery embolization (UAE) is a type of noninvasive treatment for symptomatic uterine fibroids. One of the complications of UAE is fibroid expulsion. Here, we report a case of a 45-year-old woman who underwent UAE for an intramural fibroid, which resulted in fibroid expulsion. To the best of our knowledge, there are only few reports of expulsion of intramural fibroids. The process of fibroid protrusion from the myometrium into the uterine cavity was depicted on magnetic resonance imaging (MRI) in this case. We discuss the risk factors and mechanisms of fibroid expulsion after UAE.

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Khotanlou, Hassan, Alireza Fallahi, Mohammad Ali Oghabian, and Mohammad Pooyan. "SEGMENTATION OF UTERINE FIBROID ON MR IMAGES BASED ON CHAN–VESE LEVEL SET METHOD AND SHAPE PRIOR MODEL." Biomedical Engineering: Applications, Basis and Communications 26, no. 02 (2014): 1450030. http://dx.doi.org/10.4015/s1016237214500306.

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Uterine fibroids are common tumors of female pelvis. Uterine artery embolization (UAE) is an effective treatment of symptomatic uterine fibroids by shrinkage of the size of these tumors. Segmentation of the fibroid region is essential for an accurate treatment strategy. Complex fibroids anatomy, nonhomogeneity region and missing boundary in some cases make this task very challenging. In this paper, we present a method to robustly segment these fibroids on magnetic resonance image (MRI). Our method is based on combination of two steps; Chan–Vese level set method and geometric shape prior model.

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Zaitseva, Marina, Sarah J. Holdsworth-Carson, Luke Waldrip, et al. "Aberrant expression and regulation of NR2F2 and CTNNB1 in uterine fibroids." REPRODUCTION 146, no. 2 (2013): 91–102. http://dx.doi.org/10.1530/rep-13-0087.

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Uterine fibroids are the most common benign tumour afflicting women of reproductive age. Despite the large healthcare burden caused by fibroids, there is only limited understanding of the molecular mechanisms that drive fibroid pathophysiology. Although a large number of genes are differentially expressed in fibroids compared with myometrium, it is likely that most of these differences are a consequence of the fibroid presence and are not causal. The aim of this study was to investigate the expression and regulation of NR2F2 and CTNNB1 based on their potential causal role in uterine fibroid pa

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Aneeta, Kumari, and Sinha Puja. "Clinico-Epidemiological Spectrum and Factors Associated with Uterine Fibroids." International Journal of Current Pharmaceutical Review and Research 16, no. 4 (2024): 239–43. https://doi.org/10.5281/zenodo.12788695.

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Aim: The aim of the present study to assess the clinical profile and factors associated with uterine fibroids attertiary health care center.Material & methods: This was a prospective study carried out in the Department of Obstetrics and Gynaecology,SKMCH, Muzaffarpur, Bihar, India for the period of 1 year. Study population were patients presenting withuterine fibroid. Total 100 patients were studied during study period.Results: Majority of the patients were in the age group of 31 -40 years followed by 41-50 years. Fibroid was notseen below 20 years. Majority of the patients with fibroid we

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Li, Bo, Fangfang Wang, Lingying Chen, and Haofei Tong. "Global epidemiological characteristics of uterine fibroids." Archives of Medical Science 19, no. 6 (2023): 1802–10. http://dx.doi.org/10.5114/aoms/171786.

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IntroductionThe aim of the study was to examine the burden of uterine fibroids at global, regional and national levels in terms of age and the Socio-demographic Index (SDI).Material and methodsData were extracted from the GBD 2019 dataset. Estimated annual percentage changes (EAPCs) were calculated to assess the incidence of uterine fibroids, and trends in disability-adjusted life years (DALYs) were examined. All measures examined were stratified by region, country, age and SDI to assess the effects of these variables on the incidence of uterine fibroids.ResultsThe global age-standardized inci

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