Academic literature on the topic 'Uterine glucose uptake'

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Journal articles on the topic "Uterine glucose uptake"

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Chandler, K. D., B. J. Leury, A. R. Bird, and A. W. Bell. "Effects of undernutrition and exercise during late pregnancy on uterine, fetal and uteroplacental metabolism in the ewe." British Journal of Nutrition 53, no. 3 (May 1985): 625–35. http://dx.doi.org/10.1079/bjn19850072.

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1. Uterine, umbilical and, by difference, uteroplacental net uptakes of oxygen, glucose, lactate and 3-hydroxybutyrate (uterine uptake only) were measured in single-pregnant ewes which were either well-fed throughout, or severely undernourished for 8–20 d during late pregnancy. All animals were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10° slope for 60 min.2. Undernutrition did not significantly affect fetal or placental weights at 143 d gestation but caused a 14% decrease in maternal live weight. Uterine blood flow was decreased by 32% and was associ
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Leury, B. J., A. R. Bird, K. D. Chandler, and A. W. Bell. "Glucose partitioning in the pregnant ewe: Effects of undernutrition and exercise." British Journal of Nutrition 64, no. 2 (September 1990): 449–62. http://dx.doi.org/10.1079/bjn19900045.

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Maternal whole-body glucose entry rate and uterine and umbilical net uptakes of glucose and oxygen were measured in single-pregnant ewes which were either well-fed throughout, or fed at 0.3–0.4 predicted energy requirement for 7–21 d during late pregnancy. All ewes were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10° slope for 60 min. Underfed ewes suffered significant decreases in live weight and had lower fetal, but not placental, weights at 140–144 d gestation. Undernutrition also caused large decreases in maternal glycaemia and glucose entry rate, w
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Bell, A. W., J. M. Kennaugh, F. C. Battaglia, E. L. Makowski, and G. Meschia. "Metabolic and circulatory studies of fetal lamb at midgestation." American Journal of Physiology-Endocrinology and Metabolism 250, no. 5 (May 1, 1986): E538—E544. http://dx.doi.org/10.1152/ajpendo.1986.250.5.e538.

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Uterine and umbilical blood flows, the placental clearance of 3H2O, uterine and umbilical uptakes of oxygen, glucose, and lactate were measured in conscious, pregnant sheep at 71-81 days gestation. Fetal weight was 210 +/- 20 g and less than half placental weight. In relation to fetal weight, umbilical flow was 468 +/- 57 ml X min-1 X kg-1, more than double normal values for the mature fetus. Clearance of 3H2O was approximately 12% of the late pregnancy value but high in relation to fetal weight (280 +/- 23 ml X min-1 X kg-1). Fetal oxygen uptake was 10.9 +/- 0.6 ml X min-1 X kg-1, approximate
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Das, Utpala G., Jing He, Richard A. Ehrhardt, William W. Hay, and Sherin U. Devaskar. "Time-dependent physiological regulation of ovine placental GLUT-3 glucose transporter protein." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 279, no. 6 (December 1, 2000): R2252—R2261. http://dx.doi.org/10.1152/ajpregu.2000.279.6.r2252.

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We immunolocalized the GLUT-3 glucose transporter isoform versus GLUT-1 in the late-gestation epitheliochorial ovine placenta, and we examined the effect of chronic maternal hyperglycemia and hypoglycemia on placental GLUT-3 concentrations. GLUT-3 was limited to the apical surface of the trophoectoderm, whereas GLUT-1 was on the basolateral and apical surfaces of this cell layer and in the epithelial cells lining the placental uterine glands. GLUT-3 concentrations declined at 17–20 days of chronic hyperglycemia ( P < 0.05), associated with increased uterine and uteroplacental net glucose up
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Hooper, S. B., D. W. Walker, and R. Harding. "Oxygen, glucose, and lactate uptake by fetus and placenta during prolonged hypoxemia." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 268, no. 2 (February 1, 1995): R303—R309. http://dx.doi.org/10.1152/ajpregu.1995.268.2.r303.

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Our aim was to compare the effects of short (4 h) and prolonged (24 h) periods of reduced uterine blood flow (RUBF) on fetal and placental uptake of O2, glucose, and lactate. In pregnant sheep, uterine and umbilical blood flows were measured under normal conditions and after 4 and 24 h of RUBF. A 50% reduction in uterine blood flow caused a 56% reduction in fetal arterial O2 saturation (SaO2). Umbilical blood flow increased from 325 +/- 33 to 378 +/- 32 ml.min-1.kg-1 (P < 0.05) after 4 h but was not different from pre-RUBF values after 24 h. O2 uptake by the gravid uterus was not altered by
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Reynolds, L. P., C. L. Ferrell, Debra A. Robertson, and S. P. Ford. "Metabolism of the gravid uterus, foetus and utero-placenta at several stages of gestation in cows." Journal of Agricultural Science 106, no. 3 (June 1986): 437–44. http://dx.doi.org/10.1017/s0021859600063309.

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SummaryTo quantify changes in rates of metabolism and nutrient uptake of gravid uteiine, foetal and utero-placental tissues throughout gestation, mature Hereford cows received surgery at 132 ± 0·6 (n = 12), 176 ± 0·5 (n = 8), 220 ±0·4 (n = 11) and 245 ±1·5 (n = 7) days after mating. Indwelling catheters were implanted into a uterine artery and vein of all cows. Foetal catheters also were implanted into an umbilical vein and foetal femoral artery and vein (days 176 and 220) or into a placental artery and two placental veins (days 132 and 245). Approximately 5 days after surgery, deuterium oxide
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Trotta, Ronald J., Manuel A. Vasquez-Hidalgo, Brandon I. Smith, Sarah A. Reed, Kristen E. Govoni, Kimberly A. Vonnahme, and Kendall C. Swanson. "248 Maternal Nutrient Restriction During Mid-gestation Decreases Uteroplacental Release and Fetal Uptake of Essential Amino Acids in Sheep." Journal of Animal Science 99, Supplement_3 (October 8, 2021): 130–31. http://dx.doi.org/10.1093/jas/skab235.238.

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Abstract To examine the effects of maternal nutrient restriction on net uteroplacental flux during mid-gestation, 14 singleton ewes (48.2 ± 4.0 kg body weight) were fed 100% (control; CON; n = 7) or 60% of nutrient requirements (restricted; RES; n = 7) from day 50–90 (mid-gestation). On day 90, uteroplacental blood flow was measured via Doppler ultrasonography and blood samples were collected from the femoral artery, uterine vein, umbilical artery, and umbilical vein. Blood vessel glucose and amino acids (AA) concentrations were measured and arterial-venous (uterine, AV; fetal, va) differences
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Tanner, Amelia R., Cameron S. Lynch, Victoria C. Kennedy, Asghar Ali, Quinton A. Winger, Paul J. Rozance, and Russell V. Anthony. "CSH RNA Interference Reduces Global Nutrient Uptake and Umbilical Blood Flow Resulting in Intrauterine Growth Restriction." International Journal of Molecular Sciences 22, no. 15 (July 29, 2021): 8150. http://dx.doi.org/10.3390/ijms22158150.

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Deficiency of the placental hormone chorionic somatomammotropin (CSH) can lead to the development of intrauterine growth restriction (IUGR). To gain insight into the physiological consequences of CSH RNA interference (RNAi), the trophectoderm of hatched blastocysts (nine days of gestational age; dGA) was infected with a lentivirus expressing either a scrambled control or CSH-specific shRNA, prior to transfer into synchronized recipient sheep. At 90 dGA, umbilical hemodynamics and fetal measurements were assessed by Doppler ultrasonography. At 120 dGA, pregnancies were fitted with vascular cath
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Thureen, Patti J., Susan M. Anderson, and William W. Hay. "Regulation of uterine and umbilical amino acid uptakes by maternal amino acid concentrations." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 279, no. 3 (September 1, 2000): R849—R859. http://dx.doi.org/10.1152/ajpregu.2000.279.3.r849.

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We tested the hypothesis that decreased fetal amino acid (AA) supply, produced by maternal hypoaminoacidemia (low AA) during hyperglycemia (HG), is reversible with maternal AA infusion and regulates fetal insulin concentration ([I]). We measured net uterine and umbilical AA uptakes during maternal HG/low AA concentration ([AA]) and after maternal intravenous infusion of a mixed AA solution. After 5 days HG, all maternal [AA] except glycine were decreased >50%, particularly essential [AA] ( P < 0.00005). Most fetal [AA] also were decreased, especially branched-chain AA ( P < 0.001). Ma
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Wallace, Jacqueline M., Deirdre A. Bourke, Raymond P. Aitken, Neil Leitch, and William W. Hay. "Blood flows and nutrient uptakes in growth-restricted pregnancies induced by overnourishing adolescent sheep." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 282, no. 4 (April 1, 2002): R1027—R1036. http://dx.doi.org/10.1152/ajpregu.00465.2001.

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To establish physiological mechanisms for fetal growth restriction in pregnant adolescent ewes we studied uterine, fetal, and uteroplacental metabolism in ewes offered a high ( n = 12) or moderate ( n = 10) dietary intake. High intakes decreased placental (226 vs. 414 g, P < 0.001) and fetal weight (3,323 vs. 4,626 g, P < 0.01). Uterine blood flow was reduced absolutely (−36%) but proportional to conceptus weight; umbilical blood flow was reduced absolutely (−37%) and per fetal weight (−15%). Uterine oxygen uptake was decreased per conceptus weight (−14%); there was no change in fetal we
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Dissertations / Theses on the topic "Uterine glucose uptake"

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Regnault, Timothy Robert Hume, of Western Sydney Hawkesbury University, Faculty of Agriculture and Horticulture, and School of Agriculture and Rural Development. "Orchestrated partitioning of maternal nutrients during ovine pregnancy." THESIS_FAH_ARD_Regnault_T.xml, 1997. http://handle.uws.edu.au:8081/1959.7/15.

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Ovine placental lactogen (oPL) is postulated to be involved in the repartitioning of maternal nutrients during pregnancy, through its effect on insulin metabolism. Ovine pancreatic insulin responses to exogenous glucose are depressed during pregnancy and this depression becomes more pronounced as gestation advances. In addition, under the hormonal environment of rising oPL and growth hormone (oGH) concentrations, maternal whole body glucose irreversible loss (GIL) increases. The percentage of GIL accounted for by uterine glucose uptake also increases with advancing gestation and increasing lit
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Regnault, Timothy Robert Hume. "Orchestrated partitioning of maternal nutrients during ovine pregnancy." Thesis, View thesis View thesis, 1997. http://handle.uws.edu.au:8081/1959.7/15.

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Ovine placental lactogen (oPL) is postulated to be involved in the repartitioning of maternal nutrients during pregnancy, through its effect on insulin metabolism. Ovine pancreatic insulin responses to exogenous glucose are depressed during pregnancy and this depression becomes more pronounced as gestation advances. In addition, under the hormonal environment of rising oPL and growth hormone (oGH) concentrations, maternal whole body glucose irreversible loss (GIL) increases. The percentage of GIL accounted for by uterine glucose uptake also increases with advancing gestation and increasing lit
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