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1

Charette, J. M., and S. J. Baserga. "The DEAD-box RNA helicase-like Utp25 is an SSU processome component." RNA 16, no. 11 (2010): 2156–69. http://dx.doi.org/10.1261/rna.2359810.

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2

Huang, Weidong, Feng Chen, Quanxin Ma, et al. "Ribosome biogenesis gene DEF/UTP25 is essential for liver homeostasis and regeneration." Science China Life Sciences 63, no. 11 (2020): 1651–64. http://dx.doi.org/10.1007/s11427-019-1635-2.

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3

Bernstein, Kara A., Jennifer E. G. Gallagher, Brianna M. Mitchell, Sander Granneman, and Susan J. Baserga. "The Small-Subunit Processome Is a Ribosome Assembly Intermediate." Eukaryotic Cell 3, no. 6 (2004): 1619–26. http://dx.doi.org/10.1128/ec.3.6.1619-1626.2004.

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ABSTRACT The small-subunit (SSU) processome is a large ribonucleoprotein required for the biogenesis of the 18S rRNA and likely corresponds to the terminal knobs visualized by electron microscopy on the 5′ end of nascent rRNAs. The original purification of the SSU processome of Saccharomyces cerevisiae resulted in the identification of 28 proteins. Here, we characterize 12 additional protein components, including five small-ribosomal-subunit proteins (Rps4, Rps6, Rps7, Rps9, and Rps14) that had previously been copurified. Our multiple criteria for including a component as a bona fide SSU proce
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4

Champion, Erica A., Bennett H. Lane, Meredith E. Jackrel, Lynne Regan, and Susan J. Baserga. "A Direct Interaction between the Utp6 Half-a-Tetratricopeptide Repeat Domain and a Specific Peptide in Utp21 Is Essential for Efficient Pre-rRNA Processing." Molecular and Cellular Biology 28, no. 21 (2008): 6547–56. http://dx.doi.org/10.1128/mcb.00906-08.

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ABSTRACT The small subunit (SSU) processome is a ribosome biogenesis intermediate that assembles from its subcomplexes onto the pre-18S rRNA with yet unknown order and structure. Here, we investigate the architecture of the UtpB subcomplex of the SSU processome, focusing on the interaction between the half-a-tetratricopeptide repeat (HAT) domain of Utp6 and a specific peptide in Utp21. We present a comprehensive map of the interactions within the UtpB subcomplex and further show that the N-terminal domain of Utp6 interacts with Utp18 while the HAT domain interacts with Utp21. Using a panel of
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5

Butterfield, Andrew. "UTP2: Higher-Order Equational Reasoning by Pointing." Electronic Proceedings in Theoretical Computer Science 167 (October 29, 2014): 14–22. http://dx.doi.org/10.4204/eptcs.167.4.

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6

Sato, Manae, Nanase Araki, Masahiro Kumeta, et al. "Interaction, mobility, and phosphorylation of human orthologues of WD repeat-containing components of the yeast SSU processome t-UTP sub-complex." Biochemistry and Cell Biology 91, no. 6 (2013): 466–75. http://dx.doi.org/10.1139/bcb-2013-0062.

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We previously proposed a dynamic scaffold model for inner nuclear structure formation. In this model, structures in inter-chromatin regions are maintained through dynamic interaction of protein complex modules, and WD repeat- and disordered region-rich proteins and others act as scaffolds for these protein complexes. In this study, three WD-repeat proteins, i.e., CIRH1A, UTP15, and WDR43, were found in the nuclear matrix fraction and speculated to be present in the human t-UTP sub-complex of SSU processomes. The results obtained as to their subnuclear localization, binding with each other, mob
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7

Rudra, Dipayan, Jaideep Mallick, Yu Zhao, and Jonathan R. Warner. "Potential Interface between Ribosomal Protein Production and Pre-rRNA Processing." Molecular and Cellular Biology 27, no. 13 (2007): 4815–24. http://dx.doi.org/10.1128/mcb.02062-06.

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ABSTRACT It has become clear that in Saccharomyces cerevisiae the transcription of ribosomal protein genes, which makes up a major proportion of the total transcription by RNA polymerase II, is controlled by the interaction of three transcription factors, Rap1, Fhl1, and Ifh1. Of these, only Rap1 binds directly to DNA and only Ifh1 is absent when transcription is repressed. We have examined further the nature of this interaction and find that Ifh1 is actually associated with at least two complexes. In addition to its association with Rap1 and Fhl1, Ifh1 forms a complex (CURI) with casein kinas
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8

Kong, RuiRui, Wei Han, H. Weidle Ulrich, Tao Ning, XiaoJuan Du, and Yang Ke. "1A6/DRIM, the human UTP20 functions in 28S and 5.8S rRNA processing." Chinese Science Bulletin 55, no. 17 (2010): 1770–76. http://dx.doi.org/10.1007/s11434-010-3166-8.

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9

Brickman, Timothy J., and Sandra K. Armstrong. "Bordetella Interspecies Allelic Variation in AlcR Inducer Requirements: Identification of a Critical Determinant of AlcR Inducer Responsiveness and Construction of an alcR(Con) Mutant Allele." Journal of Bacteriology 184, no. 6 (2002): 1530–39. http://dx.doi.org/10.1128/jb.184.6.1530-1539.2002.

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ABSTRACT Previous studies established the critical roles of AlcR and alcaligin inducer in positive regulation of alcaligin siderophore biosynthesis and transport genes in Bordetella pertussis and Bordetella bronchiseptica. Transcriptional analyses using plasmid-borne alcR genes of B. pertussis UT25 and B. bronchiseptica B013N to complement the alcR defect of B. bronchiseptica strain BRM13 (ΔalcR1 alcA::mini-Tn5 lacZ1) revealed interspecies differences in AlcR inducer requirements for activation of alcABCDER operon transcription. Whereas the B. pertussis UT25 AlcR protein retained strong induce
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10

An, Weidong, Yifei Du, and Keqiong Ye. "Structural and functional analysis of Utp24, an endonuclease for processing 18S ribosomal RNA." PLOS ONE 13, no. 4 (2018): e0195723. http://dx.doi.org/10.1371/journal.pone.0195723.

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11

Dez, C., M. Dlakic, and D. Tollervey. "Roles of the HEAT repeat proteins Utp10 and Utp20 in 40S ribosome maturation." RNA 13, no. 9 (2007): 1516–27. http://dx.doi.org/10.1261/rna.609807.

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12

Sondalle, S. B., S. J. Baserga, and P. C. Yelick. "The Contributions of the Ribosome Biogenesis Protein Utp5/WDR43 to Craniofacial Development." Journal of Dental Research 95, no. 11 (2016): 1214–20. http://dx.doi.org/10.1177/0022034516651077.

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13

Fu, Zhiqin, Conghui Wang, Yaqing Chen, Xiang Zhang, Xinyu Wang, and Xing Xie. "Down-regulation of UTP23 promotes paclitaxel resistance and predicts poorer prognosis in ovarian cancer." Pathology - Research and Practice 215, no. 11 (2019): 152625. http://dx.doi.org/10.1016/j.prp.2019.152625.

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14

Mouillesseaux, Kevin, and Jau-Nian Chen. "Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos." PLoS ONE 6, no. 9 (2011): e25013. http://dx.doi.org/10.1371/journal.pone.0025013.

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15

Wang, You, Jiangying Liu, Hong Zhao, et al. "Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing." Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773, no. 6 (2007): 863–68. http://dx.doi.org/10.1016/j.bbamcr.2007.04.002.

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16

Bagheri, Negar, Masoud Ahmadzadeh, and Ramin Heydari. "Effects ofPseudomonas fluorescensstrain UTPF5 on the mobility, mortality and hatching of root-knot nematodeMeloidogyne javanica." Archives Of Phytopathology And Plant Protection 47, no. 6 (2013): 744–52. http://dx.doi.org/10.1080/03235408.2013.820868.

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17

Lu, J., M. Sun, and K. Ye. "Structural and functional analysis of Utp23, a yeast ribosome synthesis factor with degenerate PIN domain." RNA 19, no. 12 (2013): 1815–24. http://dx.doi.org/10.1261/rna.040808.113.

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18

Cheng, Jingdong, Benjamin Lau, Giuseppe La Venuta, et al. "90S pre-ribosome transformation into the primordial 40S subunit." Science 369, no. 6510 (2020): 1470–76. http://dx.doi.org/10.1126/science.abb4119.

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Production of small ribosomal subunits initially requires the formation of a 90S precursor followed by an enigmatic process of restructuring into the primordial pre-40S subunit. We elucidate this process by biochemical and cryo–electron microscopy analysis of intermediates along this pathway in yeast. First, the remodeling RNA helicase Dhr1 engages the 90S pre-ribosome, followed by Utp24 endonuclease–driven RNA cleavage at site A1, thereby separating the 5′-external transcribed spacer (ETS) from 18S ribosomal RNA. Next, the 5′-ETS and 90S assembly factors become dislodged, but this occurs sequ
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19

Tenge, Victoria R., Jared Knowles, and Jill L. Johnson. "The Ribosomal Biogenesis Protein Utp21 Interacts with Hsp90 and Has Differing Requirements for Hsp90-Associated Proteins." PLoS ONE 9, no. 3 (2014): e92569. http://dx.doi.org/10.1371/journal.pone.0092569.

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20

Leng, Xue Song, Kai Hua Ran, and Yan Dong Wang. "A Study of Poor Conductor’s Thermal Conductivity Coefficient Measurement." Applied Mechanics and Materials 333-335 (July 2013): 327–31. http://dx.doi.org/10.4028/www.scientific.net/amm.333-335.327.

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When measuring the thermal conductivities of poor conductor with steady-state method, some errors should be introduced through the process of the experimental principle derivation to the experimental data measurement. To satisfy the need of measurement, this study aims to improve the structure of the “TC-I1 Type thermal conductivity measuring apparatus” correspondingly: we placed two fans at the side of the cooling plate, thus effectively control the stability of the strong-force convection cooling environment. This study chose digital thermometer of UT325 Type to collect temperature signals,
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21

Wells, Graeme R., Franziska Weichmann, David Colvin, et al. "The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans." Nucleic Acids Research 44, no. 11 (2016): 5399–409. http://dx.doi.org/10.1093/nar/gkw213.

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22

Wells, Graeme R., Franziska Weichmann, David Colvin, et al. "The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans." Nucleic Acids Research 44, no. 18 (2016): 9016. http://dx.doi.org/10.1093/nar/gkw645.

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23

Pérez-Fernández, Jorge, Pilar Martín-Marcos, and Mercedes Dosil. "Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes." Nucleic Acids Research 39, no. 18 (2011): 8105–21. http://dx.doi.org/10.1093/nar/gkr508.

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24

Zhang, Cheng, Jinzhong Lin, Weixiao Liu, Xining Chen, Rongchang Chen, and Keqiong Ye. "Structure of Utp21 Tandem WD Domain Provides Insight into the Organization of the UTPB Complex Involved in Ribosome Synthesis." PLoS ONE 9, no. 1 (2014): e86540. http://dx.doi.org/10.1371/journal.pone.0086540.

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25

Goldfeder, Mauricio B., and Carla C. Oliveira. "Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA." FEBS Journal 277, no. 13 (2010): 2838–52. http://dx.doi.org/10.1111/j.1742-4658.2010.07701.x.

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26

Bleichert, F., S. Granneman, Y. N. Osheim, A. L. Beyer, and S. J. Baserga. "The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation." Proceedings of the National Academy of Sciences 103, no. 25 (2006): 9464–69. http://dx.doi.org/10.1073/pnas.0603673103.

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27

Karami, Muhammad, Ainalem Nega, Ahdyeh Mosadegh, and Hamid Nikraz. "Evaluation of Permanent Deformation of BRA Modified Asphalt Paving Mixtures Based on Dynamic Creep Test Analysis." Advanced Engineering Forum 16 (April 2016): 69–81. http://dx.doi.org/10.4028/www.scientific.net/aef.16.69.

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The main objective this study is to evaluate the permanent deformation of buton rock asphalt (BRA) modified asphalt paving mixtures using dynamic creep test so that long term deformation behavior of asphalt mixtures can be characterized. The dynamic creep test was conducted on unmodified and BRA modified asphalt mixture using UTM25 machine. Asphalt cement of C170 from a regional supplier in Western Australia was used as the base asphalt binder for unmodified asphalt mixture; and BRA modified asphalt mixtures were made by substituting the base asphalt with 10, 20, and 30% (by weight of total as
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28

Wada, Kouko, Manae Sato, Nanase Araki, et al. "Dynamics of WD-repeat containing proteins in SSU processome components." Biochemistry and Cell Biology 92, no. 3 (2014): 191–99. http://dx.doi.org/10.1139/bcb-2014-0007.

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Nine WD-repeat containing proteins in human SSU processome components have been found in a HeLa cell nuclear matrix fraction. In these proteins, t-UTP sub-complex components, i.e., CIRH1A, UTP15, and WDR43, were shown to be immobilized in the fibrillar centers of nucleoli in living cells. In this study, the dynamics of the remaining six proteins fused with green fluorescent protein (GFP), i.e., PWP2-GFP, TBL3-GFP, GFP-UTP18, GFP-NOL10, GFP-WDR46, and GFP-WDSOF1, were examined in living cells. The findings were as follows. (i) The majority of UTP-B sub-complex components, i.e., PWP2-GFP, TBL3-G
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29

Choque, Elodie, Marlène Marcellin, Odile Burlet-Schiltz, Olivier Gadal, and Christophe Dez. "The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit inSaccharomyces cerevisiae." RNA Biology 8, no. 6 (2011): 1158–72. http://dx.doi.org/10.4161/rna.8.6.17699.

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30

Uteile, F. R., M. I. Godwin-Egein, and V. C. Okereke. "Evaluation of Growth of Toxigenic Strain of Aspergillus flavus on Turmeric-Based Media at Different Water Activities." NIGERIAN ANNALS OF PURE AND APPLIED SCIENCES 1 (March 13, 2019): 8–12. http://dx.doi.org/10.46912/napas.55.

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Climatic conditions of the rain forest ecological zone of Nigeria favour the growth of Aspergillus flavus and subsequent aflatoxin production. This study was carried out to investigate the effect of water activity (0.85, 0.9, 0.95, 0.98 and 0.995 a ) on the lag phase prior to growth and mycelial growth of a toxigenic strain of A. flavus on turmeric-based media at 28±2oC after 12 days incubation period. Four different varieties; UT14, UT25, UT35 and UT46 obtained from National Root Crop Research Institute (NRCRI), Abia State and used in the preparation of the different media. A toxigenic strain
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31

Carrillo-Fasio, J. A., J. A. Martínez-Gallardo, F. Ayala-Tafoya, C. A. López-Orona, R. Allende-Molar, and J. E. Retes-Manjarrez. "Screening for Resistance to Meloidogyne enterolobii in Capsicum annuum Landraces From Mexico." Plant Disease 104, no. 3 (2020): 817–22. http://dx.doi.org/10.1094/pdis-04-19-0718-re.

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Meloidogyne enterolobii has become an economically important plant parasitic nematode worldwide because of its high aggressiveness, increasing geographic distribution, wide host range, and pathogenicity in pepper (Capsicum annuum) cultivars carrying resistance genes to Meloidogyne incognita, Meloidogyne arenaria, and Meloidogyne javanica. The objectives of this study were to identify landraces of peppers resistant to M. enterolobii and analyze the relationship between resistance indicators and the phenotype parameters of plant height, stem width, leaf length, leaf width, relative chlorophyll,
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32

HODGE, KENYAITA M., SUMEI LU, MICHELLE LEONARD, et al. "CRISPR Mediated Deletion of a Proxy 19.2kb Distal to the T2D GWAS-Implicated SLC30A8 R325W Variant Impacts RAD21 and UTP23 Gene Expression in HepG2 Cells." Diabetes 67, Supplement 1 (2018): 1714—P. http://dx.doi.org/10.2337/db18-1714-p.

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33

Black, Joshua J., Richa Sardana, Ezzeddine W. Elmir, and Arlen W. Johnson. "Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae." PLOS Genetics 16, no. 12 (2020): e1009215. http://dx.doi.org/10.1371/journal.pgen.1009215.

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The first metastable assembly intermediate of the eukaryotic ribosomal small subunit (SSU) is the SSU Processome, a large complex of RNA and protein factors that is thought to represent an early checkpoint in the assembly pathway. Transition of the SSU Processome towards continued maturation requires the removal of the U3 snoRNA and biogenesis factors as well as ribosomal RNA processing. While the factors that drive these events are largely known, how they do so is not. The methyltransferase Bud23 has a role during this transition, but its function, beyond the nonessential methylation of ribos
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34

Zorkoltseva, I. V., N. M. Belonogova, G. R. Svishcheva, A. V. Kirichenko, and T. I. Axenovich. "In silico mapping of coronary artery disease genes." Vavilov Journal of Genetics and Breeding 23, no. 8 (2020): 1037–46. http://dx.doi.org/10.18699/vj19.585.

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To date, more than 100 loci associated with coronary artery disease (CAD) have been detected in large-scale genome-wide studies. For some of the several hundreds of genes located in these loci, roles in the pathogenesis of the disease have been shown. However, the genetic mechanisms and specific genes controlling this disease are still not fully understood. This study is aimed at in silico search for new CAD genes. We performed a gene-based association analysis, where all polymorphic variants within a gene are analyzed simultaneously. The analysis was based on the results of the genome-wide as
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35

Hohrman, Kaitlyn, Davi Gonçalves, Kevin A. Morano, and Jill L. Johnson. "Disrupting progression of the yeast Hsp90 folding pathway at different transition points results in client-specific maturation defects." Genetics 217, no. 3 (2021). http://dx.doi.org/10.1093/genetics/iyab009.

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Abstract The protein molecular chaperone Hsp90 (Heat shock protein, 90 kilodalton) plays multiple roles in the biogenesis and regulation of client proteins impacting myriad aspects of cellular physiology. Amino acid alterations located throughout Saccharomyces cerevisiae Hsp90 have been shown to result in reduced client activity and temperature-sensitive growth defects. Although some Hsp90 mutants have been shown to affect activity of particular clients more than others, the mechanistic basis of client-specific effects is unknown. We found that Hsp90 mutants that disrupt the early step of Hsp7
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36

Sharifi, Rouhallah, Masoud Ahmadzadeh, Abbas Sharifi-Tehrani, and Khalil Talebi-Jahromi. "Pyoverdine Production in Pseudomonas Fluorescens UTPF5 and its Association with Suppression of Common Bean Damping off Caused by Rhizoctonia Solani (Kühn)." Journal of Plant Protection Research 50, no. 1 (2010). http://dx.doi.org/10.2478/v10045-010-0013-5.

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37

Yamase, Y., H. Horibe, K. Kato, et al. "P3718Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz745.0572.

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Abstract Background Given that substantial genetic components have been shown in ischemic stroke, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH), a heritability may be higher in early-onset than late-onset individuals with these conditions. Although genome-wide association studies have identified various genes and loci significantly associated with ischemic stroke, ICH, or intracranial aneurysm mainly in European ancestry populations, genetic variants that contribute to susceptibility to these disorders in Japanese individuals remain to be identified definitively. Purpose Th
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