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Dissertations / Theses on the topic 'UUID'

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1

Roy, Malini. "Shape-shifters : Romantic-era representations of the child in the Wollstonecraft-Godwin family circle." Thesis, University of Oxford, 2008. http://ora.ouls.ox.ac.uk/objects/uuid:59d59e07-eb4d-46b3-a7c972cd12102b2d.

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2

Krznaric, Anton. "License Management for EBITool." Thesis, Högskolan Kristianstad, Sektionen för hälsa och samhälle, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-10175.

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This degree project deals with license management for EBITool. It´s about providing protection and monitoring for a Java Application via a license server, and the construction of it. An analysis that discusses the approach and other possible courses of action is also included. Additionally, it covers a discussion of a prototype implementation of the model solution from the analysis. The prototype is a Java EE application that deploys to JBoss AS7. It´s developed using the JBoss Developer Studio 5.0.0, an Eclipse IDE with JBoss Tools preinstalled. It exposes web services to Java Applications th
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Ruedin, Didier. "Symbolic and ideological representation in national parliaments : a cross-national comparison of the representation of women, ethnic groups and issue positions in national parliaments /." Thesis, University of Oxford, 2009. http://ora.ouls.ox.ac.uk/objects/uuid:94320eba-9ccd-4bfa-90c8-230462fe2eb8.

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4

Andrews, Tara L. "Prolegomena to a critical edition of the Chronicle of Matthew of Edessa, with a discussion of computer-aided methods used to edit the text." Thesis, University of Oxford, 2009. http://ora.ouls.ox.ac.uk/objects/uuid%3A67ea947c-e3fc-4363-a289-c345e61eb2eb.

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5

Spitz, Roland. "Subject and person : an essay on self-reference and personal identity." Thesis, University of Oxford, 1992. http://ora.ox.ac.uk/objects/uuid:52fc98df-408e-4c2e-b3b1-43edaa37cfd3.

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6

Jones, Mark R. "Intersection topologies." Thesis, University of Oxford, 1993. http://ora.ox.ac.uk/objects/uuid:292194e8-84c7-4c42-be33-a915b0e30067.

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7

Walker, Jonathan Charles. "Asymmetric synthesis via iron acyl complexes." Thesis, University of Oxford, 1986. http://ora.ox.ac.uk/objects/uuid:55cfc478-5868-474f-9d2b-532218ec6fd6.

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8

Horscroft, Nigel John. "Orbivirus non-structural protein NS2 : its role in virus replication." Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:9b550db6-dd9d-4127-941f-93eab2b6e038.

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9

Weiss, Michael. "Surfactant adsorption and Marangoni flow in liquid jets." Thesis, University of Oxford, 2004. http://ora.ox.ac.uk/objects/uuid:7e313dbf-30b6-4ad7-8607-c75e89b084eb.

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Sugden, Kimberly J. "Animal ambassadors and talking products : a cultural history of advertising trade-characters." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:4487a28c-b634-4d62-85ec-00afd3f2739b.

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11

Hadley, Gina Louise. "Mechanisms underlying the endogenous neuroprotection of hamartin in ischaemic stroke." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:1560ec7f-15cb-4c2d-b55d-2ac2bc653dfd.

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Introduction: Hamartin has been shown to mediate the endogenous resistance of Cornu Ammonis 3 (CA3) neurons to ischaemia. Proposed mechanisms concern the inhibition of mammalian target of rapamycin (mTOR) which could promote productive autophagy and prevent endoplasmic reticulum (ER) stress. A small molecule targeted at these pathways could protect neurons and buy valuable time for recanalization therapy for stroke. Methods: In vivo, the modified four vessel occlusion model of global cerebral ischaemia was used in male Wistar rats. A temporal and spatial profile for hamartin and mTOR proteins
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Virkar, Shefali Vidya. "The politics of implementing e-government for development : the ecology of games shaping property tax administration in Bangalore city, India." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:1bf0c6ae-213a-4d40-852e-5c0186099644.

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The purpose of this thesis is to examine the role of government in encouraging fiscal compliance from the theoretical perspective of the ‘Ecology of Games’; and, both, in tandem with, as well as nuanced by, the analytical model of the ‘Design-Actuality Gap Framework’. Conceptual representations of human behaviour in formal complex institutions, located within Behavioural Economics and Political Game Theory, presuppose that it is possible for government agencies to strategically influence the behavioural preferences and the consumption patterns of individual actors and groups within society. Th
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Vaz, Ana. "Interpersonal influence and network effects on voting behavior : experimental evidence from Mozambique." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:855b1ad0-e77b-4c02-99be-49ce88d50a81.

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During the 2009 Mozambican elections a randomized controlled trial implemented a voter education campaign. My thesis analyses the peer effects triggered by that campaign. The first essay looks at peer effects within the household. The second essay (co-authored with Marcel Fafchamps and Pedro Vicente) focuses on peer effects at the village level. The campaign targeted heads of household or their spouse (i.e., the primary target). In the first essay (Chapter 2) I test the effect of the campaign on other household members. I interpret this effect as evidence of interpersonal influence exerted by
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Schaupp, Anna-Lena. "The role of innate lymphoid cells in intestinal inflammation." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:04f72eb0-8e32-427a-9fe0-b271e71101ef.

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A breakdown of intestinal homeostasis due to dysregulated immune responses against intestinal bacteria underlies the pathogenesis of inflammatory bowel disease (IBD) in genetically susceptible individuals. Amongst mucosal immune cells, innate lymphoid cells (ILCs) are a heterogeneous group of cells whose functions in pathogenic inflammatory processes in the intestine are beginning to emerge from experimental murine models. However, less is known about the role of ILCs in chronic intestinal inflammation in humans. In this thesis, human ILCs were examined in the context of IBD and potential mech
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Ang, Gauri. "Investigating the relationship between sleep, circadian rhythms, and cognition in mouse models of schizophrenia." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:4b0161df-9827-4729-811f-d89c086c7dd1.

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Rackham, Thomas. "Ultrasound segmentation tools and their application to assess fetal nutritional health." Thesis, University of Oxford, 2016. http://ora.ox.ac.uk/objects/uuid:5d102b18-dd32-4004-8aa5-b04242139daa.

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Maternal diet can have a great impact on the health and development of the fetus. Poor fetal nutrition has been linked to the development of a set of conditions in later life, such as coronary heart disease, type 2 diabetes and hypertension, while restricted growth can result in hypogylcemia, hypocalcemia, hypothermia, polycythemia, hyperbilirubinemia and cerebral palsy. High alcohol consumption during pregnancy can result in Fetal Alcohol Syndrome, a condition that can cause growth retardation, lowered intelligence and craniofacial defects. Current biometric assessment of the fetus involves s
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17

Aunesluoma, Juhana. "Britain, Sweden and the Cold War, 1945-54." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:00e60ac6-30f1-49ad-857c-276451937cee.

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This thesis explores the ways in which British policy contributed to Sweden's Western connection in the early cold war. It considers the extent to which an analysis of British policy is necessary to an understanding of how the cold war shaped the Nordic region and whether there was a special part for Britain in the ways in which Sweden sought to be bound to the Western powers economically, politically and militarily. A central conclusion is that British policy was instrumental in establishing the conditions whereby Sweden could reconcile the conflicting demands of its official foreign policy o
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18

Bell, Louise Carol. "Electron transport reactions of denitrification." Thesis, University of Oxford, 1990. https://ora.ox.ac.uk/objects/uuid:9625557a-fe52-4c94-bc1f-a544275df344.

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A study is reported which demonstrates that electron transport to the reductase reactions of denitrification in the bacterium Thiosphaera pantotropha can occur aerobically. Use of dark-type electrodes has demonstrated that the N<sub>2</sub>O reductase enzyme of this organism is active under aerobic conditions, and that O<sub>2</sub> and N<sub>2</sub>O reduction can occur simultaneously. The reduction of NO<sub>3</sub><sup>-</sup> to N<sub>2</sub> gas, even under aerobic conditions, is shown to proceed via NO as an intermediate. It is concluded that the reaction of NO with O<sub>2</sub> must be
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Robinson, Thurstan H. "City and country in Pisidia from classical antiquity to the Middle Ages : Ariassos, Sia and their territories." Thesis, University of Oxford, 2002. https://ora.ox.ac.uk/objects/uuid:533c8eb5-99a1-4444-9e32-1354d7700566.

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This thesis provides a study of the growth and decline of two small Pisidian urban settlements, Sia and Ariassos, with an especial focus on the relationship, both social and economic, between town and country. The thesis addresses the subject primarily chronologically, although chapter two is diachronic. The first chapter provides an historical and geographical introduction to the subject. The complexities of the ethnic and cultural environment in which the two cities were founded are discussed along with the history of early settlement in the region. The succeeding chapters present, discuss a
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Fine, Philip Arnold. "Some aspects of hemispheric asymmetry and face processing." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:9a298284-651f-4be9-ae82-2d8862154e47.

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The eventual aims of this thesis were threefold. The first was to investigate the patterns of impairments suffered by prosopagnosic subjects, measuring both reaction times and errors, with conclusions being drawn about the heterogeneity of the neurological disorder. Three prosopagnosic subjects were tested on a number of face processing tasks, investigating facial identity matching, facial expression matching and the perception of eye gaze direction. They were found to have different patterns of impairments, reflecting the different causes of their prosopagnosia. The second aim was to investig
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Schlueter, Thorsten. "Banks as financial advisers : a comparative study in English and German law." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:261a382c-f2bd-4607-aa63-462e456e7d56.

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This thesis deals with law concerned with the role of banks as their customers' financial advisers in England and Germany. At present, the law related to financial advice in England and Germany appears to be a motley conglomerate of isolated concepts and lines of authority which fail to form a homogenous body of rules capable of guiding those who are involved in the banking business. Recent developments such as the 'misselling' of pension funds and other investment products have undermined consumer confidence in the financial services industry and have raised the question whether the present l
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22

Hobson, George Hull. "Towards a doctrine of providence : a response to contemporary critiques." Thesis, University of Oxford, 1989. https://ora.ox.ac.uk/objects/uuid:3b13825b-80de-470c-9148-ea9a9fcec8aa.

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This essay is an attempt to find an approach to the Christian doctrine of providence which takes account of modern resistance to traditional formulations even while criticizing some current assumptions that make inevitable --mistakenly, we believe-- a clash between the scientific view of reality and the biblical picture of a governing and intervening God. Our objective is not to develop a doctrine of providence as such, but simply to set in place some of the epistemological and theological conditions that would make such a doctrinal development possible today. Our investigation is set against
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Hernandez-Gomez, Luis Hector. "Crack initiation under shock loading : validation of a new testing technique." Thesis, University of Oxford, 1992. https://ora.ox.ac.uk/objects/uuid:5276163f-74b8-4ec4-bcfe-e77c69f063ac.

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The evaluation of the dynamic fracture properties with the current impact testing techniques is subject of some controversy, because the crack initiation conditions cannot be established with accuracy. Besides, some of them are limited to low loading velocities and the evaluations are made following a static approach. In consequence, a fundamental study is required with two aims, namely, a development of a new impact testing technique and the analysis of the extension of the fracture mechanics concepts to crack initiation under dynamic loading. These are the objectives of this research project
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24

Gregory, David St John. "Prediction, design and characterisation of metal binding sites in antibodies." Thesis, University of Oxford, 1992. https://ora.ox.ac.uk/objects/uuid:630ede76-2db6-4e59-bdbe-d337d4fe07a9.

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The design and creation of a functional metalloanti body is presented. A survey of metalloprotein structures was carried out to determine the common structural features of metal binding sites. Metal ligands were then introduced into hypervariable loop 11 of the anti-lysozyme antibody HyHEL-5 and the site comprehensively modelled. The final model was used as a basis for site-directed mutagenesis and mutant antibodies were produced using a Xenopus laevis oocyte expression system. Antigen binding studies showed the mutants to have an affinity for lysozyme equivalent to the parent antibody, while
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Fido, Deborah R. E. "Teaching controversial environmental issues in 16-19 A level geography : possibilities and problems." Thesis, University of Oxford, 1999. https://ora.ox.ac.uk/objects/uuid:7ff29bea-35bc-416d-ab76-9409fb09d8be.

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Environmental issues are often controversial and involve a range of possible viewpoints or attitudes. They are poorly understood hi the general population and, even amongst well respected scientists, there is often little consensus as to the causes and effects of environmental problems. Teachers are sometimes accused of exacerbating this situation by indoctrinating children with simplistic 'green slogans', rather than teaching a deeper understanding of the complexity of the issues. However, the advice provided for teachers is contradictory: much of the literature on teaching environmental issu
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Winch, Dinah. "Sexual slander and its social context in England, c. 1660-1700, with special reference to Cheshire and Sussex." Thesis, University of Oxford, 1999. https://ora.ox.ac.uk/objects/uuid:907c6610-c584-4da0-afb1-9b2bf9832da5.

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A number of historians have studied the meanings of reputation in early modern English society through the medium of defamation cases in the church courts. More recent work has tended to focus on the gendering of participation in ecclesiastical litigation and the differences in the ways that men and women constructed and maintained their good names. This thesis takes a broader approach, and places defamation cases firmly in their legal and social context. The main focus of this thesis is a sample of defamation cases from the Chester consistory court in the later seventeenth century; this is su
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Lawson, Peter R. "Characterisation of the murine gene and the porcine cDNA for lung surfactant protein D and genetic mapping of murine complement components using a novel approach." Thesis, University of Oxford, 2000. https://ora.ox.ac.uk/objects/uuid:050fecd9-5cd7-4928-b81b-8f9dffee56fc.

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The work in this thesis describes the isolation and characterisation of the mouse surfactant protein D (SP-D) gene (Sftpd). This gene has been show to span 8 exons across 14 kb of DNA sequence and displays an overall organisation similar to the other collectin genes. The complete 5' untranslated region of the mRNA was also cloned which allowed the identification of the transcription start site for SP-D. Subsequently, the analysis of the promoter region of Sftpd revealed positional conservation of a number of transcription factor binding sites between the murine and human SP-D genes and the bov
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Olavesen, Mark G. "Characterisation of a cluster of novel genes in the human major histocompatibility complex." Thesis, University of Oxford, 1993. https://ora.ox.ac.uk/objects/uuid:3340fd57-26ca-4172-8f85-0fb07f2d7d24.

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The human MHC has been shown to be associated with susceptibility to a large number of diseases. Within the MHC class III region, which consists of a ~1,100kb segment of DNA located between the class I and class II multigene families, at least 38 genes have been identified, some of which could be involved in disease susceptibility. Analyses of the homologous mouse H-2S region have localised two loci responsible for susceptibility to experimental autoimmune orchitis, Orch-1, and corticosteroid-induced cleft palate, Cps-1, to an ~100kb segment of DNA. The characterisation of four genes located w
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Cox, Nicholas P. G. "Ideas and action : emergence of technical innovation and financial discourse." Thesis, University of Oxford, 1992. https://ora.ox.ac.uk/objects/uuid:3ab9bd55-c966-4314-9efa-ad9038f4b633.

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This thesis investigates how people's ideas lead to technical innovations, and looks at the problems and setbacks along the way. The research uses data gathered from two major case-studies, several minor ones, and from a wide range of potential sources of finance for innovation. The majority of this data was obtained through free-format interviews with the people involved, although one of the major case-studies used personal letters to access an innovation at the turn of the century. This demonstrated the utility of 'historical' data for management research. The orientation is qualitative and
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Saith, Ruhi. "Relationships between follicle, oocyte and embryo features and the developmental potential of human IVF embryos : an investigation." Thesis, University of Oxford, 1996. https://ora.ox.ac.uk/objects/uuid:3c970960-6f8e-4c03-9e42-9282ba00f189.

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This dissertation reports on an investigation into relationships between human embryo, oocyte and follicular features and the developmental potential of the associated IVF embryos on transfer. An improved understanding could yield insights into biological factors influencing the development process. Besides, identifying the features associated with a good developmental potential could assist embryologists in an informed selection of the 'best' embryos for transfer. Previous studies with the same broad goal have suffered from a number of limitations. The present study attempts to overcome some
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Board, John Arnold. "Computer simulation of spectral properties of ionic systems." Thesis, University of Oxford, 1986. https://ora.ox.ac.uk/objects/uuid:948decd0-2dc0-42cd-982f-c5d9a3bad1b2.

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The technique of Molecular Dynamics (MD) computer simulation is coupled with the interrelated theories of light scattering and atomic polarisability to develop and test models for the Raman scattering from alkali halide systems. The primary interest is in the spectrum and intensity of the scattering from melts, but scattering from crystals is also considered. Two computationally tractable models for the Raman scattering are developed. One, a qualitative model capable of reproducing light scattering lineshapes in Nal, is based on approximations to the quantum-mechanical transition rates for the
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Sullivan, Kevin P. "Wrestling with angels : a study of the relationship between angels and humans in late Second Temple Judaism and early Christianity." Thesis, University of Oxford, 2002. https://ora.ox.ac.uk/objects/uuid:9d295b26-9dcf-454a-9862-d00b41594573.

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Much of the extant literature from the kte Second Temple and early Christian periods (200BCE 100CE) contains material about angels. This dissertation is an investigation into the understanding during this period of the relationship between angels and humans. It serves two purposes: (1) it contributes to our understanding of ideas about angels in this period by surveying all of the available evidence and considering evidence that has not previously been studied in detail, and (2) it concludes, contrary to recent studies by Fletcher- Louis and Gieschen, that a clear distinction was maintained be
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Mahood, Aurelea Denise. "Books for the morning-room table : popular readings of British modernism, 1920-1929." Thesis, University of Oxford, 2003. https://ora.ox.ac.uk/objects/uuid:03da3ca3-4454-4576-816d-8e66cb8de296.

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This thesis examines the presentation of modernism to mainstream (or non-specialist) readers in England during the 1920s. My research attempts to answer how and why modernism migrated from Blast to Vogue to become, in the words of Raymond Mortimer, 'the new fixed forms of our present moment'. I do this through an analysis of the critical incorporation and commercial assimilation of modernism as played out in three women's magazines The Queen, Vogue and Time and Tide published in Britain between the First and Second World Wars. I look at the networks of writers, publications, editors, reviewers
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Broom, Kerry Anne. "MRI investigation of a model of chronic inflammation in the CNS." Thesis, University of Oxford, 2003. https://ora.ox.ac.uk/objects/uuid:252e7c5e-45e7-4a25-895c-d7f075d8cbfc.

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Magnetic resonance imaging (MRI) is an established clinical tool for diagnosing Multiple Sclerosis (MS), the archetypal CNS neuroinflammatory disease. The aim of this work was to develop and characterise a chronic demyelinating inflammatory lesion, like those in MS, using MRI, histology and immunocytochemistry, to identify MR-markers of disease activity and to correlate these with developing histopathology. The second aim of this work was to investigate the effect of a peripheral infection on a quiescent CNS lesion, since infections have been hypothesised to be important in the exacerbation of
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Gorsuch, Neil M. "The right to receive assistance in suicide and euthanasia, with particular reference to the law of the United States." Thesis, University of Oxford, 2004. https://ora.ox.ac.uk/objects/uuid:688e5b8c-bb06-4d86-abe0-440a7666ffc1.

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Whether to legalize assisted suicide and euthanasia is among the most hotly debated legal and public policy issues today in the United States, as it is in many countries. In this Thesis, I first (in Chapters I and II) isolate the critical questions in this debate, the answers to which will likely determine the fate of assisted suicide and euthanasia in America's courts and legislatures: Is there historical precedent for allowing the practices? Do fairness concerns dictate that we must permit assisted suicide and euthanasia because we allow patients to refuse life-sustaining treatment? Do princ
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Cookson, James. "Supramolecular chemistry using the dithiocarbamate ligand." Thesis, University of Oxford, 2004. https://ora.ox.ac.uk/objects/uuid:88c7067e-37c8-4144-b8ee-dfe7003cb0b6.

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García, Lina María Salazar. "Enablers and constraints of creation and sharing of knowledge assets : a case of NGO policy advocacy." Thesis, University of Oxford, 2006. https://ora.ox.ac.uk/objects/uuid:4b7b0106-4004-45a8-b7d7-fdd1a6f9f60d.

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This dissertation aims to develop and validate a conceptual framework about the enablers and constraints for the creation and sharing of knowledge assets. Knowledge assets are understood as a subset of dispositions to act that is embedded in individuals, groups or artefacts and that allows us to economise the consumption of resources for a given amount of effort (Boisot 1998). The creation of knowledge assets within organisations is seen as a knower-dependent, social and non-linear process of learning that builds on information. Enablers and constraints can be found at any part of this learnin
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Schachner, Lukas Amadeus. "Economic production in the monasteries of Egypt and Oriens, AD 320-800." Thesis, University of Oxford, 2005. https://ora.ox.ac.uk/objects/uuid:5b2807f2-baa2-4d15-9127-b1316d31cd88.

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This thesis is a comprehensive, multi-disciplinary, qualitative and quantitative appraisal of the monastic economy in late Antiquity and the period of early Islam. Based on the textual and archaeological evidence of over 1,000 monasteries in Egypt and Oriens, this thesis combines both an in-depth analysis and an overall appraisal of monastic production. It follows an internal and an external, a microlevel and an integrative approach. It considers literary texts, papyri, inscriptions, colophons and published archaeological remains, especially in Syria and Palestine. The analysis of fieldwork da
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Flavell, W. R. "Electron spectroscopy of metal oxides." Thesis, University of Oxford, 1986. https://ora.ox.ac.uk/objects/uuid:6b72b77e-5bf5-4b48-bf89-77d5a2d78350.

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The validity of the classical dielectric theory of HREELS is investigated. Group theory is employed to obtain a tabulation of SO phonon modes expected to appear strongly in the spectra of given faces of many common crystal structures. The effects of crystalline anisotropy and surface defects are considered in detail. The theoretical investigation is used in conjunction with experiment to obtain a more detailed understanding of the HREELS of rutile (110), (100) and (001) surfaces than has been obtained previously. XPS, UPS and HREELS are used to investigate the surface composition and electroni
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Poli, de Figueiredo Carlos Eduardo. "Membrane transport alterations in disease states." Thesis, University of Oxford, 1992. https://ora.ox.ac.uk/objects/uuid:0b081bcd-4484-474c-bdb0-83e14da8265b.

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The present thesis investigates cell membrane abnormalities in selected diseases. Membrane transport systems are studied in chronic renal failure (CRF), endstage diabetic nephropathy, renal transplantation and atherosclerotic vascular disease. The role of membrane cholesterol concentration in modulating transport activity is also explored. Erythrocyte choline uptake is elevated in CRF and here it is shown that transporter activity returns to normal following a successful kidney transplant. Choline uptake recovers in parallel to the plasma creatinine changes. Plasma factors are suggested to pla
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Lane, Andrew N. "Abd al-Ghani al-Nabulusi's (1641-1731) commentary on Ibn Arabi's 'Fusus al-Hikam' : an analysis and interpretation." Thesis, University of Oxford, 2001. https://ora.ox.ac.uk/objects/uuid:533fc636-91c8-42fd-a40b-ac9771ad591c.

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This thesis is an analysis and interpretation of six chapters from al-Nabulusi's commentary. One of these is an account of his intentions for writing the commentary and the other five are commentaries on parts of the Fusus al-hikam. These chapters chosen from al-Nabulusi's commentary treat important subjects in the Fusus al-hikam which exemplify Ibn 'Arabi's thought particularly well. They are concerned with certain issues which were perceived to have a special importance in the Islamic religious tradition. One issue, for example, is that of Pharaoh's profession of faith which was a prominent
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White, Ben. "Consultation, commissions and context : a comparative study of the Law Commission and the Australian Law Reform Commission." Thesis, University of Oxford, 2004. https://ora.ox.ac.uk/objects/uuid:3e4ac1be-ae55-40b2-8f2f-4421d0cfa243.

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This thesis compares the consultation conducted by the Law Commission ('LC') and the Australian Law Reform Commission ('ALRC'). Its first goal is to describe the process in detail, which begins with the purposes of consultation. Next, the process of consultation is described with a discussion of each of the techniques employed by the Commissions. Although there is much overlap in how the LC and the ALRC consult, they do approach the exercise differently and these differences are discussed. The description of the Commissions' consultation concludes by examining its impact. A second goal is to c
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Howells, David. "Vacuum deposited coatings on polyester films." Thesis, University of Oxford, 2006. https://ora.ox.ac.uk/objects/uuid:14c63b4c-1dad-4420-8d96-c15ff9188c57.

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The work contained in this thesis examines how the properties of polyester film substrates affect the structure and performance of thin coatings vacuum-deposited upon them, particularly with regards to their function as gas barriers for use in packaging. By modifying the surface of a PET film prior to deposition, with either oxygen or argon plasma, an increase in adhesion between the polymer and coating by 50% occurs for both aluminium and SiOₓ layers. A reduction in the density of pinhole defects is also observed after such treatment. A set of silicon oxide (SiOₓ) coatings, deposited using a
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Farr, Helen Katherine. "The eukaryotic flagellum in health and disease." Thesis, University of Oxford, 2007. https://ora.ox.ac.uk/objects/uuid:665ed1ac-1b40-44fb-8cec-966fefcebe03.

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The 9 + 2 microtubule axoneme of flagella and cilia represents one of the most iconic structures built by eukaryotic cells and organisms. Some cilia are motile, whilst others serve as sensory organelles, and can variously possess 9+2, 9+0 axonemes and other associated structures. The recent emergence of ciliary dysfunction as a cause of human disease has renewed interest in these organelles, with several genomic and proteomic studies of cilia and flagella now published from various systems. I identified ten genes from such screens, and functionally characterised them in the flagellate protozoa
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Blanchard, Rohner Géraldine. "Persistence of protection against invasive bacteria : memory B cell responses in infants after immunisation." Thesis, University of Oxford, 2008. https://ora.ox.ac.uk/objects/uuid:328b5ab7-6dbd-48fb-b5e6-b682c060753a.

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Rapid waning of antibody and vaccine effectiveness is observed following infant immunisation with protein-polysaccharide conjugate vaccines. This is despite the demonstrable presence of immunological memory. However, disease can develop within a few days of carriage acquisition of encapsulated bacteria. Persistence of functional antibody, therefore, appears to be the key determinant of long-term protection against invasive bacterial diseases. Antibody persistence is thought to depend on the survival of long-lived plasma cells and memory B cells generated in germinal centres (GC). Using the ELI
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Clark, Melanie Jane. "The structure of MRC OX-2 membrane glycoprotein." Thesis, University of Oxford, 1985. https://ora.ox.ac.uk/objects/uuid:4a98764e-7d08-4cda-a3aa-f50409c63383.

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The mouse monoclonal antibody MRC OX-2 recognises a rat cell surface glycoprotein of M<sub>R</sub> about 45,000 which is expressed on brain and lymphoid tissues. The OX-2 antigen is of interest because its tissue distribution and biochemical properties are similar to Thy-1, a cell surface antigen which is known to have a structure resembling an immunoglobulin domain. In this thesis, the structure of OX-2 antigen is determined to evaluate whether it shares sequence homology with Thy-1 and immunoglobulins. OX-2 antigen was purified from rat brain by monoclonal antibody affinity chromatography, a
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Leitz, Christian. "The economic relations between Nazi Germany and Franco Spain, 1936-1945." Thesis, University of Oxford, 1994. https://ora.ox.ac.uk/objects/uuid:4b43eb26-a59b-4b94-ad66-1f00dafc2ba5.

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During the course of the Spanish Civil War Nazi Germany's intervention on behalf of General Francisco Franco and his fellow insurgents became increasingly dominated by economic considerations. National Socialist policies vis-à-vis Nationalist Spain developed into a programme of large-scale economic exploitation. Under the command of Hermann Goring two companies were founded in Spain in late July 1936 (HISMA) and in Berlin in early October 1936 (ROWAK) to take control not only of National Socialist supply operations for Franco but also of the whole economic relationship between Nazi Germany an
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Saldanha, Richard A. "Graph-theoretic methods in discrimination and classification." Thesis, University of Oxford, 1998. https://ora.ox.ac.uk/objects/uuid:3a06dee1-00e9-4b56-be8e-e991a570ced6.

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This thesis is concerned with the graphical modelling of multivariate data. The main aim of graphical modelling is to provide an easy to understand visual representation of, often complex, data relationships by fitting graphs to data. The graphs consist of nodes denoting random variables and connecting lines or edges are used to depict variable dependencies. Equivalently, the absence of particular edges in a graph describe conditional independencies between random variables. The resulting structure is called a conditional independence graph. The use of conditional independence graphs as a guid
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Abbott, Shaun Douglas. "Mechanistic studies on isopenicillin N synthase." Thesis, University of Oxford, 1991. https://ora.ox.ac.uk/objects/uuid:0124fa37-2d7a-43b5-a3e9-c49be4125be2.

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The mechanism of penicillin formation through the action of the enzyme isopenicillin N synthase (IPNS) on the substrate δ-(L-α-aminoadipoyl)-L-cysteinyl-D-valine and synthetic analogues, still raises many unresolved questions, despite many years' extensive investigation. In order to investigate the stereochemistry of formation of the second ring in the product, N-δ-(L-α-aminoadipoyl)-3α-hydroxymethylpenicillin, resulting from incubation of δ-(L-α-aminoadipoyl)- L-cysteinyl-D-vinylglycine with IPNS, the deuterium labelled tripeptides δ-(L-α-aminoadipoyl)- L-cysteinyl-E-[3,4-<sup>2</sup>H<sub>2<
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Morgan, Gareth Edwin. "The transcriptional regulation of the gene for human clotting factor IX." Thesis, University of Oxford, 1997. https://ora.ox.ac.uk/objects/uuid:62bd1e20-2cf6-430a-9649-53d942fa09f1.

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Haemophilia B Leyden is a rare form of haemophilia B in which patients suffer from a bleeding disorder in childhood but completely recover in adulthood. These patients all have point mutations in the gene promoter between nucleotides -21→+13 which cause this altered expression pattern. An unusual patient with a -26 G→C mutation, haemophilia B Brandenburg, did not recover from his bleeding disorder during puberty. It was suggested that this was due to the disruption of the binding of the androgen receptor (AR) to an androgen response element (ARE) in the promoter (-36→- 22). To obtain further e
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