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Journal articles on the topic 'Uvaria chamae'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Edem, Gabriel. "Exploring the Scientific Basis behind the Therapeutic Efficacy of Uvaria chamae: A Major Plus to Alternative Medicine." New Medical Innovations and Research 4, no. 6 (2023): 01–07. https://doi.org/10.31579/2767-7370/060.

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Background: From time immemorial, medicinal plants have been used in the treatment and management of diseases, Uvaria chamae is such plant. The aim of this study was to unravel and explore the scientific basis of the root extract of the plant behind its effectiveness in ameliorating illnesses using several biochemical and pharmacological assays. Materials and Methods: Uvaria chamae roots were obtained from a local community in Akwa Ibom State of Nigeria. The roots were washed, air-dried, blended and soaked in ethanol for few days, filtered and the filtrate dried in a water bath. The dried samp

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Sani, A., S. Uba, K. I. Omoniyi, and A. H. Mikail. "PHYSICO-CHEMICAL CHARACTERIZATION OF UVARIA CHAMAE OIL AND QUALITY ASSESSMENT OF BIODIESEL PRODUCED FROM Uvaria chamae." FUDMA JOURNAL OF SCIENCES 7, no. 1 (2023): 261–66. http://dx.doi.org/10.33003/fjs-2023-0701-1305.

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This research studied the potential of the seed oil of Uvaria chamae for biodiesel production.The oil was extracted using a soxhlet extractor and n-hexane as a solvent before being transesterified into biodiesel. The results obtained showed a low yield of 12.5 % for the extracted oil. The oil showed a high acid value of 14.02± 0.09 mgKOH/g, which indicated high free fatty acid content and the percentage yield of the biodiesel produced was 88.35± 0.5%. The profile of methyl esters showed that unsaturated linoleic methyl ester was dominant. The results suggested that Uvaria chamae seed oil posse

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Edem GD, Sakpa CL, and Ezeuko VC. "Premalignant features of the prostate can be ameliorated by Uvaria chamae root extract: Modeling prostate cancer with cadmium and alternative treatment option in adult Wistar rats." Ibom Medical Journal 18, no. 1 (2025): 45–59. https://doi.org/10.61386/imj.v18i1.589.

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Background: Prostate cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in males worldwide. Mortality attributed with prostate cancer is strongly associated with the age of an individual with relatively higher incidence noticed among aged males. Aim: The present study was carried out to assess the ameliorative effects of Uvaria chamae root extract on cadmium-induced carcinogenic potentials in adult male Wistar rats. Materials and Methods: Sixty (60) adult male rats weighing between 200-210g were used in the current study. They were randomly divided into 10 grou

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Bamba, Bourahima, Comoé Koffi Donatien Benie, Abou Ouattara, Dahiro Noël Doukourou, Richard Kamou Kamou, and Karamoko Ouattara. "Teneurs en phénols totaux, activités antioxydantes des macérés et décocté des feuilles de Uvaria chamae P. Beauv. (Annonaceae)." International Journal of Biological and Chemical Sciences 15, no. 1 (2021): 54–67. http://dx.doi.org/10.4314/ijbcs.v15i1.6.

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Uvaria chamae est une plante de la biodiversité Ivoirienne utilisée en médecine traditionnelle. Malgré les vertus biologiques et thérapeutiques de cette plante, peu d’informations sur la teneur en phénols totaux et l’activité antioxydante existent. L’objectif de cette étude était d’évaluer la teneur en phénols totaux, l’activité antioxydante de macéré aqueux, de macéré éthanolique et de décocté aqueux des feuilles de Uvaria chamae. La teneur en phénols totaux a été effectuée par la méthode de Folin-Ciocalteu. L’activité antioxydante a été évaluée par la méthode de piégeage du DPPH (2,2-dipheny

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Odunowo, Omobolaji. "In Silico Design of Novel Bioactive Molecules to Treat Breast Cancer with Uvaria Chamae Derivatives: A Computational Approach." Science, Technology & Public Policy 9, no. 1 (2025): 36–46. https://doi.org/10.11648/j.stpp.20250901.14.

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Breast cancer, which causes abnormal growth in breast tissue and can spread to other parts of the body, is difficult to treat due to the detrimental effects of traditional treatments such as radiation, chemotherapy, and surgery. Uvaria chamae a plant from the Annonaceae family, has antioxidant and antiproliferative characteristics, making it an alternative herbal treatment for cancer. The study aims to assess the bioactivity of Uvaria chamae leaf chemicals against the human placental aromatase in the breast cancer signaling pathway using a protein-ligand networking approach and molecular docki

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G.D, Edem. "Cadmium Toxicity in the Seminal Vesicles and Lipid Profile of Wistar Rats: Can Uvaria chamae Ameliorate the Effect?" Clinical Research and Clinical Reports 3, no. 1 (2024): 01–08. http://dx.doi.org/10.31579/2835-8325/060.

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This research investigated the capacity of Uvaria chamae in alleviating cadmium-induced toxicity in the seminal vesicles and lipid profile of Wistar rats, addressing a critical gap in current knowledge. Cadmium, a hazardous heavy metal, poses substantial risks to male reproductive health. Conducted with 25 Wistar rats under controlled conditions, the study involved local sourcing of Uvaria chamae, extracting its bioative ingredients through alcohol maceration. Dosages for cadmium and the extract were meticulously determined for five experimental groups including the control group, with rats ac

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7

Edem, Donatus Gabriel, Christopher Lucky Sakpa, and Vitalis Chukwuma Ezeuko. "Ethanol root extract of <i>Uvaria chamae</i> down-regulates Ki-67 in cadmium chloride-induced prostate pre-malignancy in Wistar rats." Journal of Phytomedicine and Therapeutics 23, no. 2 (2024): 1582–97. https://doi.org/10.4314/jopat.v23i2.15.

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Prostate malignancy is one of the most diagnosed malignancies in men worldwide and a major health problem to men in both developed and developing world. Currently, several medicinal plants have been reported to possess anti-malignant property, hence we decided to investigate this property in Uvaria chamae (UC) on Ki-67 which is a prognostic factor in prostate malignancy. Emphasis was also placed on oxidative stress markers. A total of sixty (60) Wistar rats were used for this investigation and were randomly divided into ten (10) groups of six (6) animals each. Group 1 served as control and rec

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8

EBI, G. C., C. J. Ifeanacho, and T. N. Kamalu. "Antimicrobial properties of Uvaria chamae stem bark." Fitoterapia 70, no. 6 (1999): 621–24. http://dx.doi.org/10.1016/s0367-326x(99)00099-4.

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9

Edem, G. D., K. O. Okon, V. C. Ezeuko, and I. N. Willie. "Anti-tumouric capacity`of <i>Uvaria chamae</i> root extract on cadmium-induced testicular solid mass tumour in Wistar rats." World Journal of Applied Science & Technology 16, no. 1 (2025): 23–28. https://doi.org/10.4314/wojast.v16i1.23.

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This study was carried out to investigate the efficacy of Uvaria chamae root extract on cadmium-induced testicular solid mass tumour. Twenty-five adult male Wistar rats were used and the experiment lasted for 8_weeks. The rats were divided into five groups of five animals each namely: Group one (control) were fed with a normal diet and distilled water, Group two; rats were administered 3_mg/kg of cadmium only, Group three; rats were administered 3_mg/kg of cadmium and treated with 500_mg/kg of Uvaria chamae root extract, Group four; rats were administered 3_mg/kg of cadmium and treated with 10

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C.C, Ogbuanu, Nwagu L.N., Ezeh, C.N., Achara, N.I., and Onwuatuegwu, J.T.C. "Proximate, nutraceutical composition and antimicrobial activities of Uvaria chamea (Udagu) seeds and oil." NEWPORT INTERNATIONAL JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES 4, no. 3 (2024): 1–10. http://dx.doi.org/10.59298/nijses/2023/33.1.0151.

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The study investigated proximate, nutraceutical composition and Antimicrobial activities of Uvaria chamea (Udagu) seeds. Standard methods were used to analyze the plant seeds for the present of nutraceutical and proximate component of the plant Uvaria chamea (Udagu) seeds. While disk diffusion method was employed to assay the the potent of the seed oil as an antimicrobial agent. Result of the proximate revealed that Uvaria chamea (Udagu) seeds contains ash (10.19 %), moisture (5.2 %), crude protein (0.09 %), crude fiber (51.81 %), total fat (26.19 %) and carbohydrate (6.52 %). While nutraceuti

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Nwakaego, Nwokolo Lorreta, Onyekwelu Kenechukwu Chibuike, Ene Martin Chukwugekwu, Adilieje Chioma Marylyn, Ezechukwu Ifunanya Ngozi, and Ezeh Richard Chukwunonye. "IN VITRO ANTIOXIDANT AND FREE RADICAL SCAVENGING POTENTIAL OF METHANOLIC EXTRACTS OF UVARIA CHAMAE LEAVES AND ROOTS." International Journal of Pharmacy and Pharmaceutical Sciences 11, no. 1 (2019): 67. http://dx.doi.org/10.22159/ijpps.2019v11i1.29330.

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Objective: This study investigated the in vitro antioxidant and free radical potentials of methanol extracts of Uvaria chamae leaves and roots.Methods: Fresh Uvaria chamae leaves and roots were air dried, pulverized and extracted using methanol. Phytochemical, total phenolic, flavonoids, antioxidant and tannin contents, DPPH, hydroxyl, and superoxide radical scavenging properties of the extracts were determined using standard methods.Results: In vitro antioxidant potentials revealed that methanol extract of Uvaria chamae leaves contains vitamin A (4871±79.21 I. U) and vitamin C (1.72±0.02%) wh

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Obia, O. C., M. A. Sonibare, and S. A. Adebodunb. "Pharmacognostic standards for Uvaria chamae P. Beauv. leaves (Annonaceae)." Nigerian Journal of Pharmaceutical Research 18, no. 2 (2023): 113–23. http://dx.doi.org/10.4314/njpr.v18i2.3.

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Background : Standardisation as a tool in quality control ensures purity, safety and efficacy of herbal medicines. Uvaria chamae from the family Annonaceae has wide medicinal application which includes its use as a febrifuge and as an anti-inflammatory.Objective: The study was aimed at developing some Pharmacognostic standards for the leaves of U. chamae.Material and Methods: Uvaria chamae plant was collected, identified and authenticated. Fresh leaves were examined macroscopically and microscopically based on standard procedures. Fluorescence behavior was assessed by adding various reagents a

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Jacques Ezechiel, Lokonon, Agbogba Felicienne, Medoatinsa Esperance, et al. "SAFETY OF UVARIA CHAMAE P. BEAUV ROOTS AQUEOUS EXTRACTS IN WISTAR RATS." International Journal of Advanced Research 10, no. 05 (2022): 782–87. http://dx.doi.org/10.21474/ijar01/14770.

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Uvaria chamae is used in the treatment of sickle cell crisis in Benin. The aim of this work is to determine the safety of Uvaria chamae roots aqueous extract in wistar rats. The aqueous extract was obtained by maceration. The tests for Acute Oral Toxicity (AOT) and of Sub-Chronic Oral Toxicity (SCT) respectively by forced gavage in a single dose of 2000 mg / Kg and 200 mg / Kg of body weight for 28 days were performed on female Wistar rats. The weight of the animals, serum creatinine, transaminases and the number of white blood cells were determined on day 0 and then on day 14 and day 28 respe

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14

Enabulele, O. I., and L. J. Ifeka. "Immunomodulatory and antimicrobial activities of methanol extract of Uvaria chamae leaves in rats." Bayero Journal of Pure and Applied Sciences 15, no. 1 (2022): 271–76. http://dx.doi.org/10.4314/bajopas.v15i1.36.

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The immunomodulatory and antimicrobial effects of methanol extract air-dried, powdered leaves of methanol extract of Uvaria chamae (MEUL) was evaluated in this study using standard methods. Graded doses (50 mg/kg body weight, 100 mg/kg body weight, 200 mg/kg body weight and 400 mg/kg body weight) of the extract were administered to winster rats. The control group was given dimethyl sulphoxide (DMSO). Immunomodulatory effect was assessed by delayed type hypersensitivity (DTH) and haemagglutination. Antimicrobial activity of the extract against some clinical bacteria isolates was also conducted.

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15

Bamba, Bourahima, Comoé Koffi Donatien Benie, Dahiro Noél Doukourou, et al. "Comparative study of the anticoagulant powers of the aqueous macerate, ethanolic macerate and aqueous decoction of the leaves of Uvaria chamae P. Beauv. (Annonaceae)." Journal of Drug Delivery and Therapeutics 11, no. 2-S (2021): 82–88. http://dx.doi.org/10.22270/jddt.v11i2-s.4668.

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Data on the anticoagulant power of Uvaria chamae, a plant used in traditional medicine, remain unknown despite its many therapeutic and biological virtues. The present study aimed to compare the anticoagulant effects of aqueous macerate, ethanolic macerate and aqueous decoction of U. chamae leaves. The anticoagulant activity of macerated and decocted U. chamae was evaluated in vitro against endogenous and exogenous coagulation pathways in a pool of displaced normal plasmas. These two pathways are explored using two global and chronometric tests including Cephalin-Kaolin Time (TCK) and Prothrom

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Ireh, Nwanneka Emilian, Emmanuel Chidiebere Ezeh, Okechukwu Paul Nsude, Kingsley John Orie, and Charles Chukwuma Chime. "Synthesis and Physico-mechanical Characterization of Polystyrene Blended with Uvaria chamae Seed Oil (UCSO) Used as a Plasticizer." Journal of Applied Chemical Science International 15, no. 1 (2024): 10–21. http://dx.doi.org/10.56557/jacsi/2024/v15i18530.

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Polystyrene has long been recognized as a versatile and cost-effective material used in several industries, such as packaging, consumer electronics, building, medical, and and food service disposables. The current research focuses on the synthesis and physico-mechanical characterization of polystyrene blended with Uvaria chamae seed oil (UCSO), used as a plasticizer. UCSO was extracted with hexane and used as a plasticizer in the suspension polymerization of styrene. The findings on the quality of the oil are as follows: oil content (12.54%), specific gravity at 25 oC (0.94 ± 0.00), acid value

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17

Monon KONE, Ouolouho Seydou COULIBALY, Adrien Mani KOUANGBE, Karamoko OUATTARA, and Adama COULIBALY. "Evaluation of the antioxidant and antibacterial activity of aqueous and ethanoic extracts of two medicinal plants used to treat diarrhea in Côte d’Ivoire." GSC Biological and Pharmaceutical Sciences 21, no. 3 (2022): 014–20. http://dx.doi.org/10.30574/gscbps.2022.21.3.0452.

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This study was initiated to evaluate the antioxidant and antibacterial activities of aqueous and ethanoic extracts of Anthocleista djalonensis and Uvaria chamae, two plants of the African pharmacopoeia used by the peoples of the northern Côte d’Ivoire to treat severe cases of diarrhea. A series of extraction by maceration was carried out. The extracts obtained were assayed by the colorimetric method and their antioxidant activity determined by spectrophotometer using the free radical scavenging (DPPH) and iron reduction (FRAP) methods. Dilution and agar diffusion methods on Mueller Hinton medi

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Ujah, Godwin, Emmanuel Busayo, Bassey Emeng, and Patience Kalu. "High doses of Uvaria chamae root extract impair sperm motility and viability." Lekovite sirovine, no. 41 (2021): 58–62. http://dx.doi.org/10.5937/leksir2141058u.

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Uvaria chamae is a tropical medicinal plant with documented antimicrobial and antimalarial activities. Agents with these activities are known to impair fertility. This study investigated the antifertility effects of ethanolic extract of U. chamae on male albino Wistar rats. Two different oral doses; 56.6 mg/kg body weight and 113.2 mg/kg body weight of the extracts were administered to low dose and high dose group, respectively. A third group served as control and received 2 mL of distilled water. There were five animals in each group. Administration lasted six weeks after which animals were s

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Fall, Djibril, Christophe Gleye, Xavier Franck, Alain Laurens, and Reynald Hocquemiller. "Cis -Bullatencin, a Linear Acetogenin from Roots of Uvaria Chamae." Natural Product Letters 16, no. 5 (2002): 315–21. http://dx.doi.org/10.1080/10575630290026437.

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Ita, Basil. "Antioxidant Activity of Cnestis ferruginea and Uvaria chamae Seed Extracts." British Journal of Pharmaceutical Research 16, no. 1 (2017): 1–8. http://dx.doi.org/10.9734/bjpr/2017/32924.

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Chikaodili, N. Obi-Ezeani, L. Onuike Amuche, J. Onuora Ifeoma, et al. "Evaluation of Fasting Plasma Glucose, Lipid Profile and Atherogenic Index of Diabetic Rats treated with Aqueous Extract of Uvaria chamae Leaves." International Journal of Life Sciences Research 11, no. 3 (2023): 24–29. https://doi.org/10.5281/zenodo.8203033.

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<strong>Abstract:</strong> Diabetes mellitus is one of the oldest non-communicable diseases affecting a greater proportion of the world’s population. <em>Uvaria chamae</em> is a medicinal plant with various health benefits. The study evaluated the fasting plasma glucose (FPG), lipid profile and atherogenic index of plasma (AIP) in diabetic rats treated with aqueous extract of <em>U. chamae</em> leaves. Diabetes was induced with alloxan monohydrate (150mg/kg body weight) intraperitoneally. Thirty (30) albino wistar rats were randomly assigned into 5 groups (I-V) of 6 rats each. Groups I a

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Koudokpon, H., N. Armstrong, T. V. Dougnon, et al. "Antibacterial Activity of Chalcone and Dihydrochalcone Compounds from Uvaria chamae Roots against Multidrug-Resistant Bacteria." BioMed Research International 2018 (August 27, 2018): 1–10. http://dx.doi.org/10.1155/2018/1453173.

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This study presents antimicrobial properties of Uvaria chamae roots, commonly used for the treatment of various infections in south Benin. Their constituents were extracted and then fractionated in order to isolate the active ingredients. Antimicrobial susceptibility tests were performed against several multidrug-resistant bacteria using the Mueller Hilton well agar diffusion method. Results showed that ethanol extracts were highly active against Gram-positive cocci. This activity was more extensive than that measured from conventional broad-spectrum antibiotics. Indeed, vancomycin-resistant e

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Oluremi, B. B., J. J. Oloche, P. D. Abiona, and C. B. Ofudi. "Antibacterial, Antibiofilm Activities and Toxicity of <i>Uvaria chamae</i> P. Beauv (Annonaceae)." Nigerian Journal of Pharmaceutical Research 20, no. 1 (2024): 91–98. http://dx.doi.org/10.4314/njpr.v20i1.10.

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Background: Bacteria biofilms are a serious global health concern. The rapid increase of antimicrobial resistance in diarrheagenic bacteria due to biofilm formation has limited the clinical usefulness of some antibiotics in circulation. Objectives: Uvaria chamae has shown broad spectrum antibacterial activity, hence the need to study its antibiofilm activity against enteroaggregative Escherichia coli (EAEC) strains implicated in paediatric diarrhoea. Methods: Samples of authenticated U. chamae root, stem and leaf were collected, air-dried, ground and extracted by cold maceration in dichloromet

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Monon, KONE, Seydou COULIBALY Ouolouho, Mani KOUANGBE Adrien, OUATTARA Karamoko, and COULIBALY Adama. "Evaluation of the antioxidant and antibacterial activity of aqueous and ethanoic extracts of two medicinal plants used to treat diarrhea in Côte d'Ivoire." GSC Biological and Pharmaceutical Sciences 21, no. 3 (2022): 014–20. https://doi.org/10.5281/zenodo.7653050.

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This study was initiated to evaluate the antioxidant and antibacterial activities of aqueous and ethanoic extracts of <em>Anthocleista djalonensis</em> and <em>Uvaria chamae</em>, two plants of the African pharmacopoeia used by the peoples of the northern Côte d’Ivoire to treat severe cases of diarrhea. A series of extraction by maceration was carried out. The extracts obtained were assayed by the colorimetric method and their antioxidant activity determined by spectrophotometer using the free radical scavenging (DPPH) and iron reduction (FRAP) methods. Dilution and

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Okwu, Donatus Ebere, and Friday Iroabuchi. "Phytochemical Composition and Biological Activities of Uvaria chamae and Clerodendoron splendens." E-Journal of Chemistry 6, no. 2 (2009): 553–60. http://dx.doi.org/10.1155/2009/190346.

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Uvaria chamaeP. Beauv andClerodendron splendensA Cheval are known to have various medicinal and therapeutic properties. Their anti-inflammatory and oxytocic properties were assessed in this study. The extracts and aspirin were found to inhibit carrageenan-induced paw oedema on albino rats and mice with a strong activity in aspirin having (80.43 %) inhibition whileU. chamaeandC. splendenshave 69.57% and 47.83% inhibition respectively. The plants extract exhibition and uterine contraction activity on guinea pig. Phytochemical studies on the plants revealed the presence of bioactive components co

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Koffi, Affouet Muriel, Coffi Kanko, Harisolo Ramiarantsoa, et al. "Dérivés phénoliques et benzéniques des huiles essentielles de trois Uvaria (Annonaceae) de Côte-d'Ivoire : Uvaria chamae (P.Beauv), Uvaria afzelii (Sc. Elliot) et Uvaria sp. (Aké Assi)." Comptes Rendus Chimie 7, no. 10-11 (2004): 997–1002. http://dx.doi.org/10.1016/j.crci.2003.12.024.

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Madubunyi, I. I., C. J. Njoko, E. O. Ibeh, and A. B. Chime. "Antihepatotoxic and Trypanocidal Effects of the Root Bark Extract of Uvaria chamae." International Journal of Pharmacognosy 34, no. 1 (1996): 34–40. http://dx.doi.org/10.1076/phbi.34.1.34.13173.

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Gabriel, Ada, Mamman Mohammed, Mohammed G. Magaji, Yusuf P. Ofemile, Ameh P. Matthew, and Isaac O. Akefe. "In Vitro and In Vivo Neutralizing Activity of Uvaria chamae Leaves Fractions on the Venom of Naja nigricollis in Albino Rat and Bovine Blood." Recent Patents on Biotechnology 14, no. 4 (2020): 295–311. http://dx.doi.org/10.2174/1872208314666200903152129.

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Background: Snakebite envenomation is a global priority ranked top among other neglected tropical diseases. There is a folkloric claim that Uvaria chamae is beneficial for the management of snakebite and wounds in African ethnobotanical surveys. Besides, there are many registered patents asserting the health benefits of U. chamae. Objective: This study aimed to investigate U. chamae’s potentials and identify candidates for the development of tools for the treatment and management of N. nigricollis envenomation. Methods: Freshly collected U. chamae leaves were air-dried, powdered, and extracted

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Jean, Robert Klotoé. "Anti-inflammatory properties of Uvaria chamae used in traditional Beninese medicine (West Africa)." Journal of Biodiversity and Environmental Sciences (JBES) 24, no. 1 (2024): 40–50. https://doi.org/10.5281/zenodo.13770871.

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Inflammatory diseases are still a major public health concern. Their management is problematic due to the harmful side-effects of anti-inflammatory drugs traditionally used in conventional medicine. Medicinal plants are a credible source for research into new anti-inflammatory drug. This study aimed to explore the anti-inflammatory properties of the roots of <em>Uvaria chamae</em>. Anti-inflammatory activity was explored using the red blood cell membrane stability test and the formalin-induced &oelig;dema model in rats. TNFα assay was used to assess immunomodulatory activity. This m

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Johnson, Atim, and Patricia Uwa. "Eco-friendly synthesis of iron nanoparticles using Uvaria chamae: Characterization and biological activity." Inorganic and Nano-Metal Chemistry 49, no. 12 (2019): 431–42. http://dx.doi.org/10.1080/24701556.2019.1661448.

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Thomas, Paul S., and Emmanuel E. Essien. "Antiglycation, antioxidant, and cytotoxic activities of Uvaria chamae root and essential oil composition." Natural Product Research 34, no. 6 (2018): 880–83. http://dx.doi.org/10.1080/14786419.2018.1504048.

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Adepiti, Awodayo O., Deborah O. Olufuwa, and Ololade A. Oyedapo. "Pharmacognostic and physicochemical evaluation of the leaf and root of <i>Uvaria chamae</i> (P. Beauv.) annonaceae." Nigerian Journal of Natural Products and Medicine 26, no. 1 (2023): 33–41. http://dx.doi.org/10.4314/njnpm.v26i1.5.

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The ethnomedicinal use of Uvaria chamae (P. Beauv) Annonaceae as an antimalarial has been scientifically justified. This study was carried out to determine the pharmacognostic and physicochemical characters of its leaf and root with a view to establishing pharmacopoeial parameters for their quality control. The fresh leaf and root of U. chamae, collected and authenticated in the IFE Herbarium, Obafemi Awolowo University, Nigeria, were preserved in ethanol (50%) while some were oven-dried and powdered. Organoleptic evaluation of the fresh samples and microscopy of the powders were carried out a

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Akolade, Oladipupo R., Alaribe S. Chinwe, Balogun T. Olalekan, et al. "Haematological and Genotoxicity Evaluations of Phytochemical Compounds from n-Hexane Extract of Uvaria chamae Stem on Selected Organs in Mice." Annals of Science and Technology 3, no. 1 (2018): 28–34. http://dx.doi.org/10.2478/ast-2018-0012.

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AbstractPhytochemical constituents of plants extracts have been well investigated as leads for drug discovery and development. However, aside their immense medicinal properties, their safety is also of paramount importance, therefore evaluating the toxicity of plants extracts and their phytochemicals is an important aspect of quality measures to meet the requirements for consumption.This study was done to identify the volatile phytochemical compounds present in n-hexane extract of Uvaria chamae stems (UCSH) with the aid of gas chromatography-mass spectrometry (GC-MS) and to evaluate the effect

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Okereke, A., O. Sanni, J. Mbonu, et al. "Evaluation of Phytochemical Constituents of Fresh Roots Aqueous and Ethanolic Extracts of the Medicinal Plants of Uvaria chamae, Anthocleista djalonensis and Euadenia eminens." Journal of Applied Sciences and Environmental Management 27, no. 3 (2023): 543–48. http://dx.doi.org/10.4314/jasem.v27i3.18.

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Phytochemicals are bioactive plant chemicals nutrients typically found in fruits, vegetables, grains, and other plant foods which may provide desirable health benefits beyond basic nutrition and can help reduce risks of major chronic diseases. This study was conducted to evaluate the phytochemical constituents of fresh roots ethanolic and aqueous extracts of medicinal plants of Uvaria chamae, Anthocleista djalonensis and Euadenia eminens using standard methods of phytochemical screening and Gas Chromatography - Mass Spectrometry (GC-MS) analysis. Phytochemical screening revealed a diverse arra

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Udoji, Ndidi Juliana, Felix E. Okieimen, and Osamuyi Henry Uwumarongie. "Effect of methanolic extract of Uvaria chamae and Cassytha filiformis on reproductive hormones of female albino rats." International Journal of Biological and Chemical Sciences 15, no. 5 (2022): 1717–24. http://dx.doi.org/10.4314/ijbcs.v15i5.1.

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The high cost of treating infertility and its associated risk prompted the need to search for a plant with fertility potentials. The effect of sub -acute (28) administration of methanolic extracts of of Uvaria chamae and Cassytha filiformis on reproductive hormones of female albino rat was investigated. A total of fourty (40) rats were used for the experiment and divided into four groups: positive and negative control groups, with two other experimental groups. The control groups receive five animals each, whereas the other two experimental groups received 15 rats each. Fifteen female albino r

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Olumese, Fidelis E., Iyere O. Onoagbe, Gerald I. Eze, and Felix O. Omoruyi. "Subchronic toxicity study of ethanolic extract of Uvaria chamae root in rats." Tropical Journal of Pharmaceutical Research 17, no. 5 (2018): 831. http://dx.doi.org/10.4314/tjpr.v17i5.12.

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Madiba, M., B. B. Oluremi, Z. Gulube, et al. "Anti-Streptococcus mutans, anti-adherence and anti-acidogenic activity of Uvaria chamae P. Beauv." Journal of Ethnopharmacology 300 (January 2023): 115673. http://dx.doi.org/10.1016/j.jep.2022.115673.

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Abu, Thomas, Edia Rex-Ogbuku, and Koki Idibiye. "A review: secondary metabolites of Uvaria chamae p. Beauv. (Annonaceae) and their biological activities." International Journal of Agriculture, Environment and Food Sciences 2, no. 4 (2018): 177–85. http://dx.doi.org/10.31015/jaefs.18031.

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Adepiti, Awodayo O., and Ezekiel O. Iwalewa. "Evaluation of the combination of Uvaria chamae (P. Beauv.) and amodiaquine in murine malaria." Journal of Ethnopharmacology 193 (December 2016): 30–35. http://dx.doi.org/10.1016/j.jep.2016.07.035.

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Afassinou, Y. M., L. K. Tokou, Y. I. Sossou, et al. "Evaluation de la toxicité subchronique in-vivo des extraits de trois plantes utilisées dans le traitement de l’hypertension artérielle dans la région autonome du Grand Lomé." Journal de la Recherche Scientifique de l’Université de Lomé 26, no. 2 (2024): 63–77. http://dx.doi.org/10.4314/jrsul.v26i2.13.

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Introduction : l’utilisation de la médecine traditionnelle dans le traitement de l’hypertension artérielle est courante au Togo. L’objectif de cette étude est d’évaluer la toxicité sub-chronique de trois plantes médicinales utilisées dans le traitement de l’hypertension artérielle à Lomé. Matériels et Méthodes : il s’est agi d’une étude expérimentale réalisée sur une période de 4 mois du 1 er août au 30 novembre 2022. Elle a consisté à évaluer la toxicité sur 28 jours de trois extraits de plantes médicinales utilisées pour traiter l’hypertension artérielle dans le district sanitaire du Grand L

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Nana, Olga, Jean Pierre Abdou, Danielle Sinkam Gozo, Fabrice Fekam Boyom, and Jean Momeni. "FT-IR Analysis of Ultrasonic-assisted Extracts of Total Alkaloid and Total Phenolic Contents from Uvaria chamae (Annonaceae) Root Bark and its Biological Effects." European Journal of Medicinal Plants 36, no. 3 (2025): 88–105. https://doi.org/10.9734/ejmp/2025/v36i31265.

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Background: The concept of sustainable development relevant nowadays creates a beneficial approach both environmentally and economically eco-friendly. This motivates the use of an innovative extraction technique with a positive environmental impact to obtain the active ingredients of plants. Aims: Besides Fourier Transform Infrared (FTIR) spectroscopy analysis of U. chamae root bark extracts. This study investigates the antioxidant and antiplasmodial potential of various crude extracts from the root bark of Uvaria chamae P. Beauv (Annonaceae). Methods: Two extraction techniques and different s

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Oboho, Diligent. "Gas Chromatography-Mass Spectroscopy and Histopathological Effects of Methanol Leaf Extract of Uvaria chamae on the Midgut of Sitophilus zeamais." International Journal of Agriculture and Biology 26, no. 06 (2021): 695–701. http://dx.doi.org/10.17957/ijab/15.1884.

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The present study was carried out to assess the effect of methanol leaf extract of Uvaria chamae using Gas Chromatography-Mass Spectrum (GC-MS) to determine the phytochemicals present and its effect on the histology of midgut of maize weevil, Sitophilus zeamais. Insects were administered with 10 mg/kg of the plant extract using diffusion method where insects were put in a petri dish containing various concentrations and observed to see the stage they begin to die due to toxicity and observed for 5 min. They were collected into foil processing paper and fixed in Bouins fluid for 24 h, repacked

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James. "IN VIVO NEUTRALIZATION OF NAJA NIGRICOLLIS VENOM BY UVARIA CHAMAE." American Journal of Biochemistry and Biotechnology 9, no. 3 (2013): 224–34. http://dx.doi.org/10.3844/ajbbsp.2013.224.234.

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Madubunyi, Ifeanyi I. "Hepatoprotective activity of Uvaria chamae root bark methanol extract against acetaminophen-induced liver lesions in rats." Comparative Clinical Pathology 21, no. 2 (2010): 127–35. http://dx.doi.org/10.1007/s00580-010-1072-8.

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Kaboré, Kayaba, Crépin Ibingou Dibala, Hemayoro Sama, Mamounata Diao, Marius K. Somda, and Mamoudou H. Dicko. "Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso." Biochemistry Research International 2024 (March 26, 2024): 1–8. http://dx.doi.org/10.1155/2024/1289859.

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The study aimed to evaluate phenolic content and antioxidant and antibacterial potentials of the fractions of the hydroethanolic extract of Uvaria chamae leaves, a food plant from Burkina Faso. Thus, the hexane, dichloromethane, ethyl acetate, and butanol fractions of the hydroalcoholic extract after drying were used to determine phenolic compound content, antioxidant activity, and antimicrobial potential on strains of pathogenic bacteria responsible for food contamination. Phytochemical analyses were performed according to standardized methods, while antioxidant activity was evaluated by DPPH

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K., Koudouvo, Denou A., Esseh K., et al. "Ethnobotanical Survey of Endangered Antimalarial and Analgesic Plants of Togo for the Safeguard of the Medicinal Biodiversity." Journal of Agriculture and Ecology Research International 12, no. 2 (2017): 1–9. https://doi.org/10.9734/JAERI/2017/29303.

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The correlation between the threat of species and the use of medicinal plants is necessary for the preservation of this biodiversity. However, in Sub-Saharan Africa, particularly in Togo, where the majority of the population use herbal medicines as first health care recourse, few actions are undertaken to make available the medicinal plants. This study aims for the identification of endangered antimalarial and analgesic medicinal plants. Ethnobotanical surveys were realized with Togolese traditional medicine practitioners of Maritime and Lomé-Commune Health Regions. Semi structured interview,

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Koudokpon, H., N. Armstrong, T. V. Dougnon, et al. "Erratum to “Antibacterial Activity of Chalcone and Dihydrochalcone Compounds from Uvaria chamae Roots against Multidrug-Resistant Bacteria”." BioMed Research International 2019 (March 3, 2019): 1. http://dx.doi.org/10.1155/2019/5962198.

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Negbenebor, H. E., W. A. Makanjuola, A. A. Denloye, and S. Nura. "Toxicity of powdered and ethanolic extracts of Uvaria chamae (Annonaceae) Bark on selected stored product insect pests." African Journal of Biotechnology 17, no. 11 (2018): 350–55. http://dx.doi.org/10.5897/ajb2017.16257.

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Obas, Jennifer Nkeiru, David Chukwu Obasi, and Kingsley Nwonu Agbafo. "Uvaria chamae Stem Extracts Possess Nephroprotective and Cardioprotective Effects Against Carbon Tetrachloride-Induced Toxicity in Albino Rats." Asian Journal of Biological Sciences 16, no. 4 (2023): 692–712. http://dx.doi.org/10.3923/ajbs.2023.692.712.

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Kongstad, Kenneth T., Sileshi G. Wubshet, Lasse Kjellerup, Anne-Marie Lund Winther, and Dan Staerk. "Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv." Fitoterapia 105 (September 2015): 102–6. http://dx.doi.org/10.1016/j.fitote.2015.06.013.

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