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Dissertations / Theses on the topic 'V-Myb'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Rivière, Didier. "Etude structurale par RMN de la protéine v-Myb." Rouen, 2004. http://www.theses.fr/2004ROUES040.

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Les protéines Myb sont des facteurs de transcription capables de contrôler la différentiation et la prolifération cellulaire. Il ne fait aujourd'hui aucun doute que les activités importantes des protéines Myb sont déterminées par leurs domaines fonctionnels. La spectroscopie RMN hétéronucléaire multidimensionnelle a été utilisée pour étudier le domaine de liaison minimale à l'ADN de la protéine v-Myb (R2R3 v-Myb) en phase aqueuse. Nous avons ainsi attribué la quasi-totalité de cette protéine. A l'aide des effets structurants secondaires, nous avons pu estimer les régions hélicoi͏̈dales de cett

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2

SORET, JOHANN. "Specificite du potentiel transformant de l'oncogene v-myb du virus de la myeloblastose aviaire (amv) et mecanismes d'activation du proto-oncogene c-myb." Paris 6, 1989. http://www.theses.fr/1989PA066467.

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L'oncogene v-myb d'amv possede un potentiel transformant restreint aux cellules hematopoietiques. Nos etudes suggerent que l'alteration des regions impliquees dans la constitution du domaine dna binding de v-myb puisse modifier cette specificite et permettre la transformation de fibroblastes de poule. L'analyse des proprietes biologiques de deux mutants qui expriment des sequences v-myb tronquees indique que les produits d'expression correspondants stimulent la proliferation des fibroblastes de poule et pourraient intervenir dans les mecanismes de replication de l'adn. Pour aborder l'etude de

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3

MERZAK, ABDERRAHIM. "Transformation partielle de fibroblastes d'embryon de poule par des mutants de l'oncogene v-myb et cooperation avec l'oncogene ej-h-ras pour la transformation de cellules d'embryon de hamster." Paris 7, 1992. http://www.theses.fr/1992PA077128.

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L'oncogene v-myb, du virus de la myeloblastose aviaire amv, code pour une proteine nucleaire la p48#v##m#y#b. Cette proteine est constituee de trois domaines importants: 1) un domaine amino-terminal de liaison a l'adn formee d'une sequence repetee trois fois (r1,r2,r3); 2) un domaine central transactivateur de la transcription et 3) un domaine de regulation negative de la transcription. L'etude par des mutants de deletion, du role de differents domaines de la p48#v##m#y#b dans sa specificite de transformation a montre que: a) la deletion de la premiere repetition r1 du domaine de liaison a l'a

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4

Li, Ruoping. "Effets de mutations ponctuelles ou de délétions dans l'oncongène v-myb des virus AMW et E26 sur la transformation des cellules myéloi͏̈des et sur la prolifération des cellules de neurorétine de poulet." Lille 1, 1989. http://www.theses.fr/1989LIL10072.

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Clonage moléculaire et séquençage du gène v-myb du rétrovirus aviaire thermosensible ts 143 E26 et mise en évidence d'une mutation impliquée dans la fixation de la protéine myb à l'ADN. Démonstration par mutagénèse du virus E26 que cette mutation est responsable du phénotype thermosensible des cellules transformées par ce virus. Mise en évidence du rôle du gène v-myb dans la stimulation in vitro des cellules de neurorétine de poulet

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5

Bechade, Catherine. "Expression des oncogènes v-myc et v-mil dans les cellules de neurorétine d'embryon de poulet." Paris 7, 1985. http://www.theses.fr/1985PA07F026.

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Le virus de carcinomatose aviaire MH2 est capable d'induire la multiplication des cellules de NR d'embryon de poulet qui normalement ne se divisent pas in vitro. Le génome de MH2 contient deux oncogènes : v-myc et v-mil. Des mutants de MH2 délétés dans le gène v-mil ont perdu la capacité d'induire la prolifération des cellules de NR. Un mutant de MH2 délété dans le gène v-myc a conservé cette propriété. Le produit du gène v-mil est donc nécessaire et suffisant à l'expression de la proprieté mitogène du MH2.

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6

Bachnou, Naïma. "Transdifferenciation in vivo et in vitro de myeoblastes cardiaques sous l'effet des oncogenes v-myc et v-erba associes." Paris 7, 1992. http://www.theses.fr/1992PA077219.

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Le virus de la myelocytomatose aviaire mc29 (porteur de l'oncogene v-myc) provoque chez l'embryon d'oiseau infecte a 3 jours d'incubation des tumeurs cardiaques et des anomalies cutanees. L'induction de ces tumeurs nous a incitee a etudier l'effet de v-myc associe a d'autres oncogenes. Avec la construction maheva (v-myc associe a v-erba sous le controle des ltr de mh2) nous confirmons que v-myc induit des rhabdomyomes cardiaques. De plus nous mettons en evidence chez l'embryon de poulet un effet de cooperation in vivo et in vitro entre v-myc et v-erba. Cette cooperation induit une transdiffere

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7

James, Leonard Philip. "Myc and Mad target genes /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/5093.

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8

Bechade, Catherine. "Role des oncogenes v-mil et v-myc dans la multiplication et la transformation des cellules embryonnaires de neuroretine en culture." Paris 7, 1989. http://www.theses.fr/1989PA077176.

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Le retrovirus aviaire mh2 induit la multiplication et la transformation des cellules de neuroretine (nr) d'embryons de poulet qui normalement ne se divisent pas. Le genome du virus mh2 contient deux oncogenes: v-mil et v-myc. L'isolement de mutants de mh2, deletes dans v-mil ou v-myc, nous a permis de preciser les proprietes biologiques de chacun des oncogenes et d'analyser les relations entre l'induction de la division cellulaire et la transformation. Le gene v-mil est responsable de la division des cellules de nr. Par contre, il induit un phenotype de transformation reduit dans les cellules

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9

Turque, Nathalie. "Effet de l'oncogène V-MYC sur la différenciation de la neurorétine d'oiseau in vitro." Lille 1, 1996. http://www.theses.fr/1996LIL10204.

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Par criblage d'une banque d'adnc construite à partir d'arnm provenant de cellules de neuroretine de caille infectées par le rétrovirus mc29 porteur de l'oncogène v-myc, ont été isoles deux clones l'un correspondant au gène pax-qnr, orthologue aviaire du gène pax-6/pax6 codant un facteur de transcription essentiel pour la formation des yeux et le deuxième, qnr-71, codant une protéine du mélanome apparentée au produit du gène silver gène. A cote de son expression déjà documentée dans le système nerveux central, nous avons mis en évidence une expression de pax-6 dans le pancréas, et plus particul

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10

Enikeev, Amir. "Monitorovací systém pro zjištění motility a polohy laboratorních zvířat po anestézii." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2019. http://www.nusl.cz/ntk/nusl-401008.

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This diplom work entitled "Monitoring system for the detection of motility and position of laboratory animals after anesthesia" focuses on the design and implementation of non-contact detection of the rat or mouse position in the enclosure with a transparent cover. The aim of this semester paper is to find suitable methods of realizing contactless detection of the position of a laboratory rat or mouse. This automatic positioning of the animal will be used as the basis for controlling the irradiator in the next follow-up work, which will "shade" animal movement and aim at the scar on the animal

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11

Starostová, Michaela. "Studium variabilního úseku onkoproteinu v-Myb." Master's thesis, 2007. http://www.nusl.cz/ntk/nusl-374380.

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- 4 - Study of the v-Myb oncoprotein variable region The aim of this thesis was to analyze the significance of the variable region of oncoprotein v-Myb. The v-myb oncogene originated in the chick through a natural recombination of the MAV1 retroviral genome with the c-myb gene, which is an important transcriptional regulator involved in hematopoiesis and other important processes in different types of vertebrate cells. In comparison with the c-myb coding sequence, the retroviral v-myb is truncated on N- and C-terminals and includes 11 point mutations. Due to both these changes and the retrovir

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12

Čermák, Vladimír. "Regulace transkripce proteiny rodin Early growth response a Myb." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-328727.

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The regulation of transcription of tens of thousands of genes in a vertebrate organism is an enormously complex phenomenon which entails the participation of thousands of various regulatory proteins. The largest functional category of these regulators is accounted for by sequence-specific DNA-binding proteins known as transcription factors. Proteins of the EGR and Myb families of transcription factors are long-studied regulators of a variety of physiological processes including cellular proliferation and differentiation. The structural and physical aspects of their function have been well char

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13

SELINGER, Martin. "Studium exprese cílových mRNA při pospiviroidní patogenezi v systému "leaf factory"." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-153082.

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The aim of this work was to identify potential mRNA targets of PTGS triggered by viroid-derived small RNAs (vsRNAs) in PSTVd-infected tomato plants (S. lycopersicum L.). We selected 47 possible gene targets using data provided by Prof. Dr. Steger (Heinrich Heine Universität, Düsseldorf, Germany) - the list of 1633 possible target mRNAs from tomato based on vsRNA:mRNA duplex prediction. The vsRNA sequences were obtained by Illumina sequencing of small RNA libraries from healthy and PSTVd-infected tomato plants. By qRT-PCR analysis we identified 6 genes with significantly altered levels of mRNA

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14

Largaespada, David Andrew. "Oncogenic collaboration between V-ABL and C-MYC." 1992. http://catalog.hathitrust.org/api/volumes/oclc/27393129.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1992.<br>Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 153-185).

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15

Hagerty, Marlon. "Trisomy 11, 12, and 16 in v-abl/myc-induced murine plasmacytomagenesis." 2008. http://hdl.handle.net/1993/3028.

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Murine plasmacytoma is induced by plastic implants, injection of paraffin oil or pristane, or through viral infection, and Myc is invariably overexpressed in the tumour cells. Although translocation and juxtaposition of the Myc locus to an immunoglobulin locus is the prominent nonrandom cytogenetic aberration observed, the significance of other karyotypic instabilities in murine plasmacytoma is not clear, including the previously observed occurrence of trisomy 11. As well as identifying new cytogenetic mutations in murine plasmacytomagenesis, this study provides evidence for their combined a

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16

Čáslavová, Kateřina. "Role těhotenství v životě ženy - "Já" nebo "My"." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-351781.

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This thesis presents data gained from qualitative research that took place in Czech Republic from February to June in 2015. Based on semi-structured interview with pregnant women analyses pregnancy experience and understanding of their own physicality. In the theoretical part of this thesis I highlight the approaches of hegemonic discourses of pregnancy and alternative structures in feminist debates. In the next part I focus on poststructuralism. The empirical part of this thesis focuses on two main parts. First, I present physicality of pregnant women and than construction pregnant women as h

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17

Hájková, Anna. "My a Oni v perspektivě společnosti a práva." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-328767.

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Abstract- We and They in the perspective of society and law This work reflects the attitude and perception of a Czech majority towards two different minorities i.e. Vietnamese and Roma. The main goal of this thesis is to describe the cultural aspects and specific values of these two minorities, to present an overview of factors that influence the way the majority and minority interact and live together. These factors are based either on legislation or on social psychological or sociological phenomena of these interactions. This work also tries to offer an answer to the questions regarding the

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18

Schwarzer, Martin. "Vliv probiotických bakterií na alergickou senzibilizaci v modelu alergie I. typu." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-329276.

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The main goal in reversing the allergy epidemic is the development of effective prophylactic strategies. Early life events, such as exposures to microbes, have a major influence on the development of balanced immune responses. Due to their ability to interact with host immune system and to modulate host immune responses probiotics, mainly bifidobacteria and lactobacilli have been used with some success in prevention of allergic disease. In order to be referred to as probiotic, bacterial strain has to undergo rigorous testing. We have selected three new Lactobacillus (L.) strains out of 24 huma

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19

Pavlova, Olga. "Antiutopie. "My" a "Oni" v české a světové próze 20. století." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-313470.

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In this thesis I mainly analyzed the canonical dystopian works, like J. Zamjatin We and G. Orwell 1984, based on this observation I circumscribe the five criteria by which the dystopian fictional world works. In the following sections, I observed the role and place of these criteria in the 20th century Czech literature works.

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20

Spurný, Matěj. "Nejsou jako my. Sociální marginalizace a integrace v období "budování nového řádu" na příkladu menšin v českém pohraničí (1945-1960)." Doctoral thesis, 2010. http://www.nusl.cz/ntk/nusl-300388.

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This work considers the changing attitudes of Czech society and its political élite towards minorities in the restored nation-state of Czechoslovakia after the Second World War and in the period of the coming to power of the Czechoslovak Communist Party and the stabilization of its dictatorship. To this end, it examines three very heterogeneous minority groups: the ethnic Germans remaining after the expulsions, the Gypsies (Roma), and the Volhynian Czechs. The Czech borderlands (former Sudetenland) were a distinctive space; the processes that took place there are analysed in detail in this wor

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21

Kadavá, Anna. "Velký Bratr a my : Jak se konstruuje soukromí v interakci diváka s formátem reality TV." Master's thesis, 2006. http://www.nusl.cz/ntk/nusl-265800.

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The central theme of this diploma is the construction of privacy in reality TV shows. Process design privacy I tried to show with strategies Television text that jsoi in reality TV shows to the formation of private use. The subject of this thesis was illustrated by looking at the three programs listed simultaneously in the Czech Republic (VyVolení Big Brother and Wife Swap), as these resources and methods used and how to participate the resulting experience private audience. Presentation of privacy in these programs I examined as key moments that are offered by their creators audience potentia

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22

Pýcha, Jaroslav. "Využití dichotomie My versus Oni v předvolebních projevech Joe Bidena a Donalda Trumpa z roku 2020." Master's thesis, 2021. http://www.nusl.cz/ntk/nusl-446509.

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This thesis aims to analyze the camping speeches of the two major candidates running for President of the Unites States in the 2020 general election and to inspect the ways in which both the candidates utilize the Us versus Them dichotomy. In doing so, the thesis provides a critique of the texts produced by the candidates and seeks to unveil their ideological motivation. As categorizing entities has a profound effect on the audience and their perception of reality, the goal is not only to unveil what entities the candidates discuss, but also to determine how they classify these entities. In ad

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23

Janušová, Martina. "Jan Pelár, muzikant, jenž by neměl být zapomenut." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-347671.

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Jan Pelar is an integral part of the cultural heritage of Wallachia. He personally represented Wallachian culture at Ethnographic Exhibition in Prague in 1895. On this occasion he obtained his first musician concession. Reportedly, he composed the Wallachian anthem, "My sme Valaši" on his way to Prague. This work will focus on his musical career and his personal life which was extraordinary. This work will focus on his musical career, his extraordinary personal life and his legacy to younger musicians.

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24

Tučková, Sabina. "Identita a mezietnické vztahy mladých Sarajevanů: Kdo stojí na opačných stranách mostu?" Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-346954.

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Sarajevo is a city in which, for centuries, people of different religions and ethnicities have lived together. But the war in the early 1990s partitioned the country into almost ethnically homogenous parts. The aim of this work is to find out, how young people between the ages of 18 - 29 years old perceive the identity of contemporary Sarajevo and to what extent they identify with the official narrative of Sarajevo as a multi-ethnic city. An online survey was conducted in March 2016 by a sample of 66 young Bosniaks, Bosnian Serbs, and Bosnian Croats. The research examines how they identify wit

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25

Škoda, Martin. "Instagram jako prostředek pro šíření trendů v gastronomii se zaměřením na specifika České republiky." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-415530.

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This diploma thesis discusses Instagram as a means for spreading trends in gastronomy with a focus on gastronomy and related trends in the field specifically from the Czech Republic. The author tries to map the influences that the online environment can have on their formation, especially the social network Instagram. After a thorough acquaintance with the environment of social networks, the social network Instagram, its influence on the spread of experiences, trends and the media environment in general, is described in more detail. The author seeks to clarify whether what is happening on this

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26

BRISUDOVÁ, Eva. "Rozvoj myšlenkových a komunikačních dovedností dětí předškolního věku v kontextu Filozofie pro děti." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-385118.

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The diploma thesis consists of theoretical and practical part. The theoretical part deals with a definition of important concepts such as philosophy for children, historical development of this program, personality of a child, communication and thinking of pre-school children. The practical part is conceived as a controlled dialogue with children in preschool education, with a great emphasis on expressing their emotions and experiencing a given situation.

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