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Journal articles on the topic 'Vaccination/inoculation'

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1

Boylston, Arthur. "The origins of vaccination: no inoculation, no vaccination." Journal of the Royal Society of Medicine 106, no. 10 (2013): 395–98. http://dx.doi.org/10.1177/0141076813499293.

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2

Shah, Shagun Bhatia, Rajiv Chawla, and Anurag Mehta. "SARS-CoV-2: Comparison of Active Immunity Acquired by Natural Exposure versus Inoculation of HCW." Galore International Journal of Health Sciences and Research 6, no. 2 (2021): 54–63. http://dx.doi.org/10.52403/gijhsr.20210408.

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Background: The immune response to vaccination is not expected to be the same in COVID-19 survivors and COVID-naïve population. There is a deficiency of specific guidelines regarding vaccination (number and temporal spacing of doses) for the burgeoning subset of population which has recovered from COVID-19 due to paucity of literature. Methodology: This prospective, observational, single-centric, case-control study compares the IgG-antibody count at two time-points (post first and second inoculation) in 33 COVID-survivors Group-P) and 31 COVID-naïve (Group-N) health care workers. Adverse event
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3

Eldaghayes, Ibrahim, Lisa Rothwell, Michael Skinner, and Pete Kaiser. "Fowlpox virus in chicken’s skin: Persistence and the local immune response at the site of inoculation." Journal of Microbiology and Infectious Diseases 14, no. 3 (2024): 131. http://dx.doi.org/10.5455/jmid.2024.v14.i3.6.

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Background: Fowlpox virus (FPV) has been used as a vector for many years. To date, surprisingly, very little data exist on the persistence of fowlpox vaccines in chicken tissues, or what kind of immune cells respond to vaccination at the site of inoculation. Although both humoral and cellular- mediated immunity (CMI) play a part in overall immunity against FPV, little is known regarding the cell-mediated immune responses to FPV infection. Aim: The main aim of this paper was to measure persistence of fowlpox vaccine in skin tissues following vaccination. Methods: One-day-old chicks were vaccina
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4

Baek, Kyeongbin, Sony Maharjan, Madhav Akauliya, et al. "Comparison of vaccination efficacy using live or ultraviolet-inactivated influenza viruses introduced by different routes in a mouse model." PLOS ONE 17, no. 10 (2022): e0275722. http://dx.doi.org/10.1371/journal.pone.0275722.

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Influenza is a major cause of highly contagious respiratory illness resulting in high mortality and morbidity worldwide. Annual vaccination is an effective way to prevent infection and complication from constantly mutating influenza strains. Vaccination utilizes preemptive inoculation with live virus, live attenuated virus, inactivated virus, or virus segments for optimal immune activation. The route of administration also affects the efficacy of the vaccination. Here, we evaluated the effects of inoculation with ultraviolet (UV)-inactivated or live influenza A virus strains and compared their
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5

Compton, Josh, and Brian Kaylor. "“The Devil and Vaccination” and Inoculation Theory." Journal of Communication and Religion 45, no. 3 (2022): 37–50. http://dx.doi.org/10.5840/jcr20224539.

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“The Devil and Vaccination,” a satirical take on Samuel Coleridge and Robert Southey’s poem, “The Devil’s Thoughts,” appeared in the July 1879 issue of The Vaccination Inquirer and Health Review—a publication that published vaccine-skeptical writings. The poem told the story of the Devil visiting a prison, encountering several people including a father imprisoned for refusing to have one of his children vaccinated. In the present rhetorical analysis, “The Devil and Vaccination” was viewed through the lens of inoculation theory—a theory more commonly used to guide a social scientific approach t
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6

Abd El-Ghany, Wafaa A. "In Ovo Vaccination Technology: An Alternative Approach to Post-Hatch Vaccination in Modern Poultry Operations." Microbiology Research 16, no. 1 (2024): 7. https://doi.org/10.3390/microbiolres16010007.

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Poultry production systems are usually exposed to important infections that could be prevented by vaccination programs. Conventional methods of vaccination such as drinking water; spray, eye, or nose inoculation; and injection are usually given after hatching and have many disadvantages. Therefore, there is a great need for searching of alternative ways for vaccination process. In ovo vaccination technology is now regarded as an alternative approach to post-hatch vaccination in modern poultry operations. This technique is effective, fast, provides uniform vaccine dosing and delivery, is suitab
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7

ELMEDULAN, ARNIELYN, and MERASOL DUYAG. "CONTEXTUAL FACTORS, VACCINATION DETERMINANTS, AND ADHERENCE TO COVID-19 INOCULATION AMONG PREGNANT WOMEN." Sprin Journal of Arts, Humanities and Social Sciences 3, no. 3 (2024): 05–11. http://dx.doi.org/10.55559/sjahss.v3i3.260.

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Background: Maternal inoculation is the most effective way to combat COVID-19, reducing morbidity in pregnant women and newborns. This study focused on investigating the factors influencing COVID-19 inoculation adherence among pregnant women in a government hospital in Paranaque City, Philippines. Research Method: Conducted through a descriptive-correlational research design involving 245 randomly selected pregnant women, the study employed three researcher-made questionnaires to gather data on contextual factors, vaccination determinants, and adherence to COVID-19 inoculation. Results: The fi
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8

Lan, Zheng, Tongli Zhang, Yu Zhang, et al. "A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccination." F1000Research 14 (May 13, 2025): 493. https://doi.org/10.12688/f1000research.162267.1.

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Background Our understanding of the human immune system’s response to viral respiratory tract infections (VRTIs) and vaccines, including the molecular mechanisms and correlates of protection, remains incomplete. Extensive transcriptomic data from inoculation and vaccination studies have been deposited in publicly available databases. However, these studies are often separate and difficult to locate. Methods To bridge this research gap, we have systematically searched and reviewed publicly available datasets from NCBI Gene Expression Omnibus (GEO), Archive of Functional Genomics Data (ArrayExpr
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9

Jo, Jeong-Eun. "The Endeavors for Universal Vaccinationand Their Impact: Focusing on Smallpox Epidemic in Shanghai, 1938-39." Korean Association for the Social History of Medicine 11 (April 30, 2023): 63–89. http://dx.doi.org/10.32365/kashm.2023.11.3.

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In this paper, we investigated what kind of efforts were made to expand vaccination amid a smallpox epidemic in Shanghai in 1938-39, as well as the significance of such efforts.
 In Shanghai, various strategies were employed to achieve universal vaccination. When it was first introduced, theories of Chinese medicine were borrowed to help people’s understanding, and various media outlets were used to promote the effect and safety of vaccination. Health institutions in the foreign concession and the Chinese elites helped to expand free vaccination. At the time, vaccination was not mandatory
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10

Ramirez, A. G., C. Despres, P. Chalela, et al. "Pilot study of peer modeling with psychological inoculation to promote coronavirus vaccination." Health Education Research 37, no. 1 (2022): 1–6. http://dx.doi.org/10.1093/her/cyab042.

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Abstract Promoting coronavirus vaccination is deterred by misinformation, ranging from elaborate conspiracy theories about sinister purposes to exaggeration of side effects, largely promulgated by social media. In this pilot study, we tested the effects of different messages on actions leading to vaccination. Two theory-based advertisements were produced for Facebook, which provided video testimonials from peer role models recommending vaccination and its benefits while providing psychological inoculation through the models’ acknowledging misinformation, rejecting it and receiving the vaccine.
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11

Mockett, A. P. A., A. Deuter, and Debra J. Southee. "Fowlpox vaccination: Routes of inoculation and pathological effects." Avian Pathology 19, no. 4 (1990): 613–25. http://dx.doi.org/10.1080/03079459008418717.

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12

Lee, Simin, Sameer ul Salam Mattoo, Chang-Gi Jeong, et al. "Intradermal Inoculation of Inactivated Foot-and-Mouth Disease Vaccine Induced Effective Immune Responses Comparable to Conventional Intramuscular Injection in Pigs." Vaccines 12, no. 2 (2024): 190. http://dx.doi.org/10.3390/vaccines12020190.

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All pigs in the Republic of Korea are given the foot-and-mouth disease virus (FMDV) vaccine intramuscularly (IM) as part of the country’s vaccination policy. However, the IM administration of the FMDV vaccine to pig results in residual vaccine components in the muscle and undesirable changes in muscle and soft tissues, causing economic losses in swine production. In this study, we evaluated whether intradermal (ID) vaccination could be proposed as an alternative to IM administration. ID vaccination (0.2 mL on each side of the neck muscle) and IM vaccination (2 mL on each side of the neck muscl
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13

Kim, Jaejo, Seung-Heon Lee, Ha-Hyun Kim, Jong-Hyeon Park, and Choi-Kyu Park. "Heterologous Prime-Boost Vaccination with Commercial FMD Vaccines Elicits a Broader Immune Response than Homologous Prime-Boost Vaccination in Pigs." Vaccines 11, no. 3 (2023): 551. http://dx.doi.org/10.3390/vaccines11030551.

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Three commercial vaccines are administered in domestic livestock farms for routine vaccination to aid for foot-and-mouth disease (FMD) control in Korea. Each vaccine contains distinct combinations of inactivated serotype O and A FMD virus (FMDV) antigens: O/Manisa + O/3039 + A/Iraq formulated in a double oil emulsion (DOE), O/Primorsky + A/Zabaikalsky formulated in a DOE, and O/Campos + A/Cruzeiro + A/2001 formulated in a single oil emulsion. Despite the recommendation for a prime-boost vaccination with the same vaccine in fattening pigs, occasional cross-inoculation is inevitable for many rea
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14

Shchelkunov, S. N., A. A. Sergeev, S. A. Pyankov, K. A. Titova, and S. N. Yakubitskiy. "Smallpox vaccination in a mouse model." Vavilov Journal of Genetics and Breeding 27, no. 6 (2023): 712–18. http://dx.doi.org/10.18699/vjgb-23-82.

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The monkeypox epidemic, which became unusually widespread among humans in 2022, has brought awareness about the necessity of smallpox vaccination of patients in the risk groups. The modern smallpox vaccine variants are introduced either intramuscularly or by skin scarification. Intramuscular vaccination cannot elicit an active immune response, since tissues at the vaccination site are immunologically poor. Skin has evolved into an immunologically important organ in mammals; therefore, intradermal delivery of a vaccine can ensure reliable protective immunity. Historically, vaccine inoculation i
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15

Dubey, J. P., D. G. Baker, S. W. Davis, J. F. Urban, and S. K. Shen. "Persistence of immunity to toxoplasmosis in pigs vaccinated with a nonpersistent strain of Toxoplasma gondii." American Journal of Veterinary Research 55, no. 7 (1994): 982–87. http://dx.doi.org/10.2460/ajvr.1994.55.07.982.

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Summary Persistence of the vaccine RH strain of Toxoplasma gondii was studied by bioassay and histologically in 14 pigs. Pigs were euthanatized 2, 4, 7, 8, 14, 15, 21, 29, 36, 42, 52, 57, and 76 days after im inoculation with 100,000 T gondii tachyzoites. Viable T gondii tachyzoites derived from the RH strain were isolated by bioassay in mice inoculated with tissues of pigs euthanatized up to 14 days after vaccination. Except for fever, pigs vaccinated im with the RH strain remained clinically normal. Two other pigs inoculated iv with 100,000 T gondii tachyzoites of the RH strain became ill, a
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16

Ghorpade, Ashok. "Inoculation indeterminate leprosy localised to a smallpox vaccination scar." Leprosy Review 78, no. 4 (2007): 398–400. http://dx.doi.org/10.47276/lr.78.4.398.

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17

Kent, Stephen J., C. Jane Dale, Scott Preiss, John Mills, Daniella Campagna, and Damian F. J. Purcell. "Vaccination with Attenuated Simian Immunodeficiency Virus by DNA Inoculation." Journal of Virology 75, no. 23 (2001): 11930–34. http://dx.doi.org/10.1128/jvi.75.23.11930-11934.2001.

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ABSTRACT Delivering attenuated lentivirus vaccines as proviral DNA would be simple and inexpensive. Inoculation of macaques with wild-type simian immunodeficiency virus strain mac239 (SIVmac239) DNA or SIVmac239 DNA containing a single deletion in the 3′nef-long terminal repeat overlap region (nef/LTR) led to sustained SIV infections and AIDS. Injection of SIVmac239 DNA containing identical deletions in both the 5′ LTR and 3′ nef/LTR resulted in attenuated SIV infections and substantial protection against subsequent mucosal SIVmac251 challenge.
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18

Brunton, Joshua S., Regan N. Theiler, Ramila Mehta, Megan E. Branda, Elizabeth Ann L. Enninga, and Vanessa E. Torbenson. "Efficacy of Rubella Vaccination after Co-Inoculation with Rhogam." Viruses 15, no. 9 (2023): 1782. http://dx.doi.org/10.3390/v15091782.

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Congenital rubella syndrome is a constellation of birth defects that can have devastating consequences, impacting approximately 100,000 births worldwide each year. The incidence is much lower in countries that routinely vaccinate their population. In the US, postnatal immunization of susceptible women is an important epidemiological strategy for the prevention of rubella as the Center for Disease Control (CDC) does not recommend administering this vaccine during pregnancy due to its nature as a live attenuated virus vaccine. However, concerns that the co-administration of rubella vaccine with
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19

Mikirtichan, Galina L. "From the history of vaccine prevention: vaccination against smallpox." Russian Pediatric Journal 19, no. 1 (2019): 55–62. http://dx.doi.org/10.18821/1560-9561-2016-19-1-55-62.

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In the article there is considered the history of vaccination against smallpox, first variolation, and then vaccination after its discovery in 1796 by E. Jenner. Until the XVIII century the inoculation method for the protection from smallpox has long been practiced in traditional medicine in several countries, as well as in certain regions of Russia, it differed in the local character, andfailed to arouse widespread. Gradually, in the XVIII century. variolation as a method of protection against smallpox becomes a common heritage and extends from Western Europe to Russia. One of the brakes ofth
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20

Cheng, Ting-Yu, Alexandra Buckley, Albert Van Geelen, et al. "Detection of pseudorabies virus antibody in swine oral fluid using a serum whole-virus indirect ELISA." Journal of Veterinary Diagnostic Investigation 32, no. 4 (2020): 535–41. http://dx.doi.org/10.1177/1040638720924386.

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We evaluated the detection of pseudorabies virus (PRV) antibodies in swine oral fluid. Oral fluid and serum samples were obtained from 40 pigs allocated to 4 treatment groups (10 pigs/group): negative control (NC); wild-type PRV inoculation (PRV 3CR Ossabaw; hereafter PRV); PRV vaccination (Ingelvac Aujeszky MLV; Boehringer Ingelheim; hereafter MLV); and PRV vaccination followed by PRV inoculation at 21 d post-vaccination (MLV-PRV). Using a serum PRV whole-virus indirect IgG ELISA (Idexx Laboratories) adapted to the oral fluid matrix, PRV antibody was detected in oral fluid samples from treatm
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21

Weiss, Robin A., and José Esparza. "The prevention and eradication of smallpox: a commentary on Sloane (1755) ‘An account of inoculation’." Philosophical Transactions of the Royal Society B: Biological Sciences 370, no. 1666 (2015): 20140378. http://dx.doi.org/10.1098/rstb.2014.0378.

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Sir Hans Sloane's account of inoculation as a means to protect against smallpox followed several earlier articles published in Philosophical Transactions on this procedure. Inoculation (also called ‘variolation’) involved the introduction of small amounts of infectious material from smallpox vesicles into the skin of healthy subjects, with the goal of inducing mild symptoms that would result in protection against the more severe naturally acquired disease. It began to be practised in England in 1721 thanks to the efforts of Lady Mary Wortley Montagu who influenced Sloane to promote its use, in
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22

Shchelkunov, Sergei N., Aleksander A. Sergeev, Ksenia A. Titova, et al. "Comparison of the Effectiveness of Transepidemal and Intradermal Immunization of Mice with the Vacinia Virus." Acta Naturae 14, no. 4 (2023): 111–18. http://dx.doi.org/10.32607/actanaturae.11857.

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The spread of the monkeypox virus infection among humans in many countries outside of Africa, which started in 2022, is now drawing the attention of the medical and scientific communities to the fact that immunization against this infection is sorely needed. According to current guidelines, immunization of people with the first-generation smallpox vaccine based on the vaccinia virus (VACV) LIVP strain, which is licensed in Russia, should be performed via transepidermal inoculation (skin scarification, s.s.). However, the long past experience of using this vaccination technique suggests that it
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23

Chen, M. J., C. Y. Wu, R. Chen, and Y. W. Wang. "HPV Vaccination and Cervical Cancer Screening in Taiwan." Journal of Global Oncology 4, Supplement 2 (2018): 235s. http://dx.doi.org/10.1200/jgo.18.94300.

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Background and context: Cervical cancer has been one of the most important cancers over the last 3 decades in Taiwan, and it still is among the top 10 cause of death for women. Aim: The aim of the policy was to achieving the following KPIs: HPV vaccine inoculation rate to 60%; 30-69 year Papanicolaou test screening rate ≥ 70%; and cervical cancer mortality dropped to 3.3/105 (baseline 1995 = 11/105). Strategy/Tactics: We provided annual Pap test for all women aged 30 years or more since 1995 and encourage women to screen at least every 3 years. We will introduce national HPV vaccination progra
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Piontkowski, Michael D., and Douglas W. Shivvers. "Evaluation of a commercially available vaccine against Corynebacterium pseudotuberculosis for use in sheep." Journal of the American Veterinary Medical Association 212, no. 11 (1998): 1765–68. http://dx.doi.org/10.2460/javma.1998.212.11.1765.

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Objective To evaluate the efficacy of a commercially available bacterin-toxoid vaccine for preventing Corynebacterium pseudotuberculosis-induced abscesses in sheep. Design Prospective randomized controlled trial. Animals 31 mixed-breed sheep seronegative for C pseudotuberculosis. Procedure Sheep were randomly assigned to vaccinate (n = 20) or nonvaccinate (11; control) groups. Sheep in the vaccinate group received 2 doses of serial A or serial B bacterin-toxoid vaccine at 4-week intervals. Serologic testing was conducted after vaccination to document an antibody response to vaccination. All sh
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Sulewska, Hanna, Karolina Ratajczak, Alicja Niewiadomska, and Katarzyna Panasiewicz. "The use of microorganisms as bio-fertilizers in the cultivation of white lupine." Open Chemistry 17, no. 1 (2019): 813–22. http://dx.doi.org/10.1515/chem-2019-0089.

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AbstractThe agricultural usability of bio-fertilizers, particularly including microbiological seed vaccines meet the recommendations for integrated protection/cultivation applicable in Poland. Combined vaccination seeds with Rhizobium bacteria together with endophitic bacteria from the group of Plant Growth Promoting Rhizobacteria (PGPR), increase the efficiency of biological nitrogen fixation and therefore stimulate the development and yielding of legume crops. This hypothesis was verified in a series of field experiments with white lupine conducted between 2016 and 2018 at Złotniki, Poland.
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Musser, Jeffrey M. B., and Kevin L. Anderson. "Effect of vaccination with an Escherichia coli bacterin-toxoid on milk production in dairy cattle." Journal of the American Veterinary Medical Association 209, no. 7 (1996): 1291–93. http://dx.doi.org/10.2460/javma.1996.209.07.1291.

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Objective To determine whether vaccination of lactating cattle with an Escherichia coli J5 bacterin-toxoid would produce a significant short-term change in milk production. Design Randomized, controlled clinical trial. Animals 84 healthy, lactating cows (42 Holsteins and 42 Jerseys). Procedure Control and vaccinated cows were paired on the basis of breed, days in milk, daily milk production 1 week prior to vaccination, and parity. One cow in each pair was inoculated IM with a commercially available bacterin-toxoid according to label directions; the other cow was given saline solution. Cows wer
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27

Leachman, Sancy A., Robert E. Tigelaar, Mark Shlyankevich, et al. "Granulocyte-Macrophage Colony-Stimulating Factor Priming plus Papillomavirus E6 DNA Vaccination: Effects on Papilloma Formation and Regression in the Cottontail Rabbit Papillomavirus-Rabbit Model." Journal of Virology 74, no. 18 (2000): 8700–8708. http://dx.doi.org/10.1128/jvi.74.18.8700-8708.2000.

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ABSTRACT A cottontail rabbit papillomavirus (CRPV) E6 DNA vaccine that induces significant protection against CRPV challenge was used in a superior vaccination regimen in which the cutaneous sites of vaccination were primed with an expression vector encoding granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine that induces differentiation and local recruitment of professional antigen-presenting cells. This treatment induced a massive influx of major histocompatibility complex class II-positive cells. In a vaccination-challenge experiment, rabbit groups were treated by E6 DNA v
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Li, Xiaoguang, Chao Liang, and Xiumei Xiao. "SARS-CoV-2 Neutralizing Antibody Levels Post COVID-19 Vaccination Based on ELISA Method—A Small Real-World Sample Exploration." Vaccines 9, no. 10 (2021): 1139. http://dx.doi.org/10.3390/vaccines9101139.

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This study investigated the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies following inoculation with the coronavirus disease (COVID-19) vaccine. From June to July 2021, 127 participants who had completed COVID-19 vaccination (inactivated SARS-CoV-2 vaccine, 64; CoronaVac, 61; CanSino, 2) were recruited and tested using SARS-CoV-2 neutralizing antibody kits. The positive detection rate (inhibition of neutralizing antibodies ≥ 30%) was calculated and stratified according to population characteristics and inoculation time. The positive rate of n
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Moya, Daniel, Diego Gómez, Paul Patiño, Nicolas Nohad Altamirano, Marcela Balzarini, and Karin Freitag. "Shoulder Injury Related to Vaccine Administration Following Misplaced SARS-CoV-2 Vaccination: A Case Report and Review of Literature." Journal of Orthopaedic Case Reports 12, no. 3 (2022): 100–103. http://dx.doi.org/10.13107/jocr.2022.v12.i03.2736.

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Introduction: To confront the SARS-CoV-2 pandemic, a large share of the population must be immunized. Intramuscular vaccination of the shoulder is the preferred technique as it is easily exposed and guarantees a good immune reaction. Local side effects, such as pain and swelling, are common after deltoid inoculation. They usually resolve within 3 days. Shoulder injury related to vaccine administration (SIRVA) should be considered if the symptoms persist. The aim of this presentation is to describe a typical case of SIRVA after SARS-CoV-2 vaccination and provide information to the general ortho
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Kishida, Shigefumi, Takaaki Nakaya, and Katsuro Hagiwara. "Vaccination with Melanoma Cells Infected with Recombinant Newcastle Disease Virus Suppresses Tumor Metastasis." SOJ Immunology 6, no. 1 (2018): 1–6. http://dx.doi.org/10.15226/2372-0948/6/1/00165.

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Newcastle Disease Virus (NDV) is an RNA virus, which infects several tumor cells and shows cellular toxicity towards them. The antitumor activity of NDV has been reported in several tumors. In this study, we evaluated the antitumor effect of a NDV-infected melanoma cell vaccine on lung metastasis based on tumor-specific immune responses in a mouse model. B16 mouse melanoma cells were infected with the GFP-expressing recombinant NDV (rNDV) to prepare the vaccine (rNDV-BV). C57BL/6 mice were then immunized twice with rNDV-BV and intravenously inoculated with B16 cells, and the number of metastas
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Xiang, Hui, Xiaojun Tang, Meng Xiao, et al. "Study on Status and Willingness towards Hepatitis B Vaccination among Migrant Workers in Chongqing, China: A Cross-Sectional Study." International Journal of Environmental Research and Public Health 16, no. 20 (2019): 4046. http://dx.doi.org/10.3390/ijerph16204046.

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Background: Rural-to-urban migrant workers may serve as a bridge population for the cross-regional spread of hepatitis B vaccination (HBV) due to frequent shifts between their work areas and homelands, and they are less likely to be covered by the national hepatitis B (HB) immunization program. This study aimed to investigate the current inoculation status of HB vaccine among migrant workers and the willingness to be vaccinated among non-vaccinated ones. Methods: We conducted a cross-sectional survey using anonymous interviews with migrant workers selected by two-stage cluster sampling from Ju
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Vitebskaya, Alisa V., Alexander B. Malahov, and Alexey Y. Rtishchev. "Vaccination and diabetes mellitus type 1 in children." Diabetes mellitus 21, no. 5 (2018): 409–18. http://dx.doi.org/10.14341/dm9345.

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Influence of vaccination on the risk of developing diabetes mellitus type 1 (DM1) has been studied by different researchers for several decades. In rodents, vaccination can prevent development of DM1. This review summarises existing literature and discusses the results of a 2016 meta-analysis, pertaining to vaccination and DM1. No vaccines appear to increase the risk of DM1. Additional investigations are needed to determine if vaccines can be considered protective against DM1.
 Patients with DM1 are at increased risk of morbidities from controllable infections. Children with DM1 should re
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Mohammad, Tasneem F., and Craig G. Burkhart. "The Importance of Vaccination Against HPV." Open Dermatology Journal 8, no. 1 (2014): 1–3. http://dx.doi.org/10.2174/1874372201408010001.

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The human papillomavirus is a DNA virus that is involved in the pathogenesis of several benign and malignant lesions. Although numerous types of HPV exist, vaccines currently target HPV’s 6, 11, 16, and 18, which are the most commonly implicated in verrucae and oral-genital neoplasms. Although the HPV vaccine has been recommended as part of the vaccination schedule in adolescents for several years, widespread inoculation has not yet become common practice. It is imperative that vaccination be more broadly instituted to decrease the incidence of HPV related lesions in both males and females
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Sumner, Rebecca P., Hongwei Ren, and Geoffrey L. Smith. "Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy." Journal of General Virology 94, no. 5 (2013): 1121–26. http://dx.doi.org/10.1099/vir.0.049700-0.

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Vectors based on vaccinia virus (VACV), the vaccine used to eradicate smallpox, are currently popular candidates for the vaccination against numerous infectious diseases including malaria and AIDS. Although VACV induces robust cellular and humoral responses, enhancing the safety and efficacy of these vectors remains an important area of research. Here, we describe the enhanced immunogenicity of a recombinant VACV Western Reserve (WR) strain lacking the immunomodulatory protein C6 (vΔC6). Intradermal infection of mice with vΔC6 was shown previously to induce smaller lesions, indicating viral at
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Cuschieri, Sarah, Amalia Hatziyianni, Marios Kantaris, Antonis Kontemeniotis, Mamas Theodorou, and Elena Pallari. "Same Pandemic Yet Different COVID-19 Vaccination Roll-Out Rates in Two Small European Islands: A Comparison between Cyprus and Malta." Healthcare 10, no. 2 (2022): 222. http://dx.doi.org/10.3390/healthcare10020222.

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A mass vaccination strategy is estimated to be the long-term solution to control COVID-19. Different European countries have committed to vaccination strategies with variable population inoculation rates. We sought to investigate the extent to which the COVID-19 vaccination strategies, inoculation rate, and COVID-19 outcome differ between Cyprus and Malta. Data were obtained from the Ministry of Health websites and COVID-19 dashboards, while vaccination data were obtained from the European Centre for Disease Prevention and Control until mid-June, 2021. Comparative assessments were performed be
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Penkert, Rhiannon R., Nehali Patel, Richard J. Webby, Ted M. Ross, and Julia L. Hurwitz. "Month of Influenza Virus Vaccination Influences Antibody Responses in Children and Adults." Vaccines 9, no. 2 (2021): 68. http://dx.doi.org/10.3390/vaccines9020068.

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The improvement of influenza virus vaccines and the development of a universal product have been long-standing goals in pre-clinical and clinical research. To meet these goals and to understand the strengths and weaknesses of current vaccine strategies, scientists routinely study human responses toward seasonal influenza vaccines. This research is frequently performed with clinical samples taken throughout an influenza season, often without strict attention to the month of inoculation for each study participant. Here, we ask how the timing of vaccination affects outcomes. Results demonstrate s
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ИСАЕВА, А. М., Ф. Е. РУСТАМОВА, Р. У. МУХАМБЕТОВА, et al. "FREQUENCY OF POST-VACCINATION REACTIONS AFTER COVID-19 VACCINATION." Farmaciâ Kazahstana, no. 4 (September 16, 2022): 34–38. http://dx.doi.org/10.53511/pharmkaz.2022.66.39.006.

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Проведен анализ среди 100 терапевтов-резидентов НАО «Национальный медицинский университет» имени С.Д.Асфендиярова, для выявления побочных эффектов после вакцинации от COVID-19. В исследование вошли следующие вакцины: Pfizer, Спутник V, Vero Cell и QazVac. В нашем исследовании мужчины составили 52% всех респондентов (n=52). В исследовании участвовали резиденты от 24 до 27 лет. Средний возраст участников составил 25,5±0,7 лет. По результатам нашего исследования, доля побочных эффектов после прививания Pfizer составила 53,3%. Причиной высокого показателя является количество резидентов, прививавши
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FEW, MARTHA. "Circulating smallpox knowledge: Guatemalan doctors, Maya Indians and designing Spain's smallpox vaccination expedition, 1780–1803." British Journal for the History of Science 43, no. 4 (2010): 519–37. http://dx.doi.org/10.1017/s000708741000124x.

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AbstractDrawing on the rich but mostly overlooked history of Guatemala's anti-smallpox campaigns in the 1780s and 1790s, this paper interweaves an analysis of the contribution of colonial medical knowledges and practical experiences with the construction and implementation of imperial science. The history of the anti-smallpox campaigns is traced from the introduction of inoculation in Guatemala in 1780 to the eve of the Spanish Crown-sponsored Royal Maritime Vaccination Expedition in 1803. The paper first analyses the development of what Guatemalan medical physician José Flores called his ‘loc
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L, Poincelot. "Onset of Protection of FeLV Vaccine Containing Purified P45 FeLV-Envelope Antigen after One Single Injection of Primary Vaccination in Cats." Vaccines & Vaccination Open Access 8, no. 2 (2023): 1–7. http://dx.doi.org/10.23880/vvoa-16000167.

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Feline Leukaemia Virus (FeLV) is a viral pathogen causing fatal disease in cat populations worldwide, mainly in young kittens with outdoor access. This study aimed to assess the protection against feline leukaemia virus (FeLV), provided by a FeLV vaccine containing purified p45 FeLV-envelope antigen (Leucogen®) after one single injection of primary vaccination in kittens. Twenty-five 9-week-old cats, negative for FeLV antibodies and antigens the day of vaccination, were randomized into two groups. One group of 10 kittens was not vaccinated and kept as control, and one group of 15 animals recei
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Wu, Shipo, Zhe Zhang, Rui Yu, et al. "Intramuscular Delivery of Adenovirus Serotype 5 Vector Expressing Humanized Protective Antigen Induces Rapid Protection against Anthrax That May Bypass Intranasally Originated Preexisting Adenovirus Immunity." Clinical and Vaccine Immunology 21, no. 2 (2013): 156–64. http://dx.doi.org/10.1128/cvi.00560-13.

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ABSTRACTDeveloping an effective anthrax vaccine that can induce a rapid and sustained immune response is a priority for the prevention of bioterrorism-associated anthrax infection. Here, we developed a recombinant replication-deficient adenovirus serotype 5-based vaccine expressing the humanized protective antigen (Ad5-PAopt). A single intramuscular injection of Ad5-PAopt resulted in rapid and robust humoral and cellular immune responses in Fisher 344 rats. Animals intramuscularly inoculated with a single dose of 108infectious units of Ad5-PAopt achieved 100% protection from challenge with 10
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Guo, Chinlin, and Wei-Chiao Chang. "Modeling-Based Estimate of the Vaccination Rate, Lockdown Rules and COVID-19." Healthcare 9, no. 10 (2021): 1245. http://dx.doi.org/10.3390/healthcare9101245.

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COVID-19 has become a severe infectious disease and has caused high morbidity and mortality worldwide. Restriction rules such as quarantine and city lockdown have been implemented to mitigate the spread of infection, leading to significant economic impacts. Fortunately, development and inoculation of COVID-19 vaccines are being conducted on an unprecedented scale. The effectiveness of vaccines raises a hope that city lockdown might not be necessary in the presence of ongoing vaccination, thereby minimizing economic loss. The question, however, is how fast and what type of vaccines should be in
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Lowen, Anice C., John Steel, Samira Mubareka, Elena Carnero, Adolfo García-Sastre, and Peter Palese. "Blocking Interhost Transmission of Influenza Virus by Vaccination in the Guinea Pig Model." Journal of Virology 83, no. 7 (2009): 2803–18. http://dx.doi.org/10.1128/jvi.02424-08.

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ABSTRACT Interventions aimed at preventing viral spread have the potential to effectively control influenza virus in all age groups, thereby reducing the burden of influenza illness. For this reason, we have examined the efficacy of vaccination in blocking the transmission of influenza viruses between guinea pigs. Three modes of immunization were compared: (i) natural infection; (ii) intramuscular administration of whole, inactivated influenza virus in 2 doses; and (iii) intranasal inoculation with live attenuated influenza virus in 2 doses. The ability of each immunization method to block the
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Rubins, Kathleen, and David A. Relman. "Progression of the Lesion at the Site of Inoculation after Smallpox Vaccination." New England Journal of Medicine 348, no. 5 (2003): 414. http://dx.doi.org/10.1056/nejmicm020924.

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SHAFEI, SAMY M., ELHAM A. EL-EBIARY, SAFWAT K. ROFAIIL, and SAHER M. GERGIS. "EVALUATION OF FOWL CHOLERA VACCINE BY MICE VACCINATION AND CHALLENGE INOCULATION SYSTEM." Egyptian Journal of Agricultural Research 81, no. 1 (2003): 311–22. http://dx.doi.org/10.21608/ejar.2003.276332.

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45

Thompson, Angela T. "To Save the Children: Smallpox Inoculation, Vaccination, and Public Health in Guanajuato, Mexico, 1797-1840." Americas 49, no. 4 (1993): 431–55. http://dx.doi.org/10.2307/1007408.

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When smallpox threatened the Mexican province of Guanajuato in October 1797, Juan de Riaño, the Intendant of Guanajuato, instituted a program of inoculation to protect the children of his province against the disease. Realizing that many parents would resist having their children inoculated, he decided to provide an example by having his own six children inoculated first, thereby encouraging other parents to bring their children forward. Accordingly, a physician made deep scratches in the arms of his children, three of whom were under the age of five, and rubbed organic matter containing live
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Pépin, Michel, Pierre Pardon, José Marly, Frédéric Lantier, and Jorge Luis Arrigo. "Acquired immunity after primary caseous lymphadenitis in sheep." American Journal of Veterinary Research 54, no. 6 (1993): 873–77. http://dx.doi.org/10.2460/ajvr.1993.54.06.873.

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Summary Caseous lymphadenitis (cla) caused by Corynebacterium pseudotuberculosis is a worldwide disease of sheep and goats and is characterized by development of pyogranulomas in lymph nodes and lungs. Control of this disease by vaccination remains controversial, although toxoid vaccines are now commercially available in some countries. To determine the efficacy of acquired immunity to control cla, the effect of primary infection on subsequent challenge exposure was investigated. Adult seronegative ewes were primarily inoculated with a streptomycin-sensitive strain of C pseudotuberculosis on t
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Araki, Tooru, Aya Kodera, Kunimi Kitada, et al. "Analysis of factors associated with development of Bacille Calmette–Guérin inoculation site change in patients with Kawasaki disease." Journal of International Medical Research 46, no. 4 (2018): 1640–48. http://dx.doi.org/10.1177/0300060518760462.

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Objective The present study was performed to identify factors associated with a Bacille Calmette–Guérin (BCG) inoculation site change in patients with Kawasaki disease (KD). Methods Among patients who had received BCG vaccination and treatment for KD at our hospital from 2005 through 2016, 177 patients born in 2005 through 2016 were enrolled. The patients were divided into those with (n = 83, change group) and without (n = 94, no-change group) a BCG site change, and the patient demographics, clinical severity, blood examination results, and echocardiographic findings were compared between the
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Fensterle, Joachim, Leander Grode, Jürgen Hess, and Stefan H. E. Kaufmann. "Effective DNA Vaccination Against Listeriosis by Prime/Boost Inoculation with the Gene Gun." Journal of Immunology 163, no. 8 (1999): 4510–18. http://dx.doi.org/10.4049/jimmunol.163.8.4510.

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Abstract Protective immunity against Listeria monocytogenes strongly depends on CD8+ T lymphocytes, and both IFN-γ secretion and target cell killing are considered relevant to protection. We analyzed whether we could induce a protective type 1 immune response by DNA vaccination with the gene gun using plasmids encoding for two immunodominant listerial Ags, listeriolysin and p60. To induce a Th1 response, we 1) coprecipitated a plasmid encoding for GM-CSF, 2) employed a prime/boost vaccination schedule with a 45-day interval, and 3) coinjected oligodeoxynucleotides (ODN) containing immunostimul
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Pukhalsky, Alexander L., Galina V. Shmarina, Maria S. Bliacher, et al. "Cytokine profile after rubella vaccine inoculation: evidence of the immunosuppressive effect of vaccination." Mediators of Inflammation 12, no. 4 (2003): 203–7. http://dx.doi.org/10.1080/09629350310001599639.

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Background:Immunization with live virus vaccines may cause an immunosuppression with lymphopaenia, impaired cytokine production and defective lymphocyte response to mitogenes. These abnormalities were described in subjects vaccinated against measles. This study was performed to analyse the host immune response related to immunosuppression in subjects vaccinated with live attenuated rubella vaccine.Methods:Eighteen schoolgirls, aged 11-13 years, were vaccinated with live attenuated rubella vaccine Rudivax®. Before immunization, and 7 and 30 days after, peripheral blood was collected. Cellular f
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Pryor, Grace E., Kelsea Marble, Ferdinand T. Velasco, Christoph U. Lehmann, and Mujeeb A. Basit. "COVID-19 Mass Vaccination Resource Calculator." Applied Clinical Informatics 12, no. 04 (2021): 774–77. http://dx.doi.org/10.1055/s-0041-1733849.

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Abstract Background Despite the recent emergency use authorization of two vaccines for the prevention of the 2019 novel coronavirus (COVID-19) disease, vaccination rates are lower than expected. Vaccination efforts may be hampered by supply, delivery, storage, patient prioritization, administration infrastructure or logistics problems. To address the last issue, our institution is sharing publically a calculator to optimize the management of staffing and facility resources in an outpatient mass vaccination effort. Objective By sharing our calculator locally and through this paper, we aim to he
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